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Stephanie H Cook, Robert-Paul Juster, Benjamin J Calebs, Justin Heinze, Alison L Miller
Much of the extant scientific research examining hypothalamic-pituitary-adrenal (HPA)-axis functioning is conducted among White heterosexuals. Very little research examines HPA-axis functioning between different minority groups. Individuals who identify as both sexual and racial minorities may experience increased stigma and discrimination that can affect HPA-axis functioning. In the current study, we examined diurnal cortisol rhythm in young White gay men (WGM) compared to young Black gay men (BGM). The sample consisted of 70 healthy gay men (mean [SD] age=22...
October 13, 2016: Psychoneuroendocrinology
C Dial, K Doh, I Thiam, P Ndoye Roth, C Moreira, G Woto-Gaye
OBJECTIVES: Describe the macroscopic and microscopic profiles of retinoblastoma (RB) in Senegal and correlate histological criteria with progression to establish severity factors. METHODOLOGY: We realized a retrospective study over 10 years (January 2005-December 2014). Only patients (n=67) who underwent histological analysis of the enucleation specimen (n=68) were followed until the end of the study. RESULTS: The tumor measured an average of 3...
October 17, 2016: Journal Français D'ophtalmologie
J L NDiaye, B Cissé, E H Ba, J F Gomis, C T Ndour, J F Molez, F B Fall, C Sokhna, B Faye, E Kouevijdin, F K Niane, M Cairns, J F Trape, C Rogier, O Gaye, B M Greenwood, P J M Milligan
BACKGROUND: It is recommended that children aged 3 months to five years of age living in areas of seasonal transmission in the sub-Sahel should receive Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) during the malaria transmission season. The purpose of this study was to evaluate the safety of SMC with SPAQ in children when delivered by community health workers in three districts in Senegal where SMC was introduced over three years, in children from 3 months of age to five years of age in the first year, then in children up to 10 years of age...
2016: PloS One
Jonathan Israel
In Barbarism and Religion, his six-volume work on the "Enlightenments" of Edward Gibbon, J. G. A. Pocock argues for a "family of enlightenments," disputing accounts, particularly Venturi's and Gay's, of it as a unified phenomenon. This article asserts, however, that Pocock's reconfiguration of different national contexts to emphasize the diversity of strands of the Enlightenment underestimates their commonality and the degree to which they fall into the recognizable currents of radical and moderate. Ultimately, Pocock's attention to the ecclesiastical and theological dimensions of the Enlightenment undermines rather than supports his argument for its pluralism...
2016: Journal of the History of Ideas
Rachel H Farr
Controversy continues to surround parenting by lesbian and gay (LG) adults and outcomes for their children. As sexual minority parents increasingly adopt children, longitudinal research about child development, parenting, and family relationships is crucial for informing such debates. In the psychological literature, family systems theory contends that children's healthy development depends upon healthy family functioning more so than family structure. From the framework of family stress theory, it was expected that longitudinal outcomes for school-age children adopted in infancy could be distinct among those with same-sex versus other-sex parents (N = 96 families)...
October 20, 2016: Developmental Psychology
Jeremy T Goldbach, Ethan H Mereish, Claire Burgess
BACKGROUND: Prescription drug, e-cigarette, smokeless tobacco, and synthetic marijuana use has risen dramatically in the United States over the past decade. OBJECTIVES: This paper investigates the use of risky substances among adolescents, and examines disparities between sexual minority (i.e., mostly heterosexual and lesbian, gay, bisexual; LGB) and heterosexual adolescents in use of novel and emerging substances. Given the public health risk and the imminence of these substances in the media, emerging drug use was examined in a county wide sample of adolescents in a Southern state...
October 19, 2016: Substance Use & Misuse
David R Driscoll, Saadia A Karim, Makoto Sano, David M Gay, Wright Jacob, Jun Yu, Yusuke Mizukami, Aarthi Gopinathan, Duncan I Jodrell, T R Jeffry Evans, Nabeel Bardeesy, Michael N Hall, Brian J Quattrochi, David S Klimstra, Simon T Barry, Owen J Sansom, Brian C Lewis, Jennifer P Morton
mTOR signaling controls several critical cellular functions and is deregulated in many cancers, including pancreatic cancer. To date, most efforts have focused on inhibiting the mTORC1 complex. However, clinical trials of mTORC1 inhibitors in pancreatic cancer have failed, raising questions about this therapeutic approach. We employed a genetic approach to delete the obligate mTORC2 subunit Rictor and identified the critical times during which tumorigenesis requires mTORC2 signaling. Rictor deletion resulted in profoundly delayed tumorigenesis...
October 6, 2016: Cancer Research
John B Fleming, Michelle Nicole Burns
OBJECTIVE: Internalized homonegativity is linked to psychological distress in sexual minorities and is thus a potential treatment target in this population. Previous studies have shown that evaluative conditioning (EC) can modify self-esteem, another self-directed attitude. The present study aimed to determine if EC deployed over the Internet could modify self-esteem and internalized homonegativity. METHOD: Gay men recruited online (N = 184) were randomly assigned to a control group or an experimental condition...
October 18, 2016: Journal of Clinical Psychology
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No abstract text is available yet for this article.
October 17, 2016: BMJ: British Medical Journal
Richard Lemke, Mathias Weber
This study investigates how men who have sex with men (MSM) use chat and dating sites based on theories of stigma-related offline behavior and online self-disclosure. We hypothesize that hidden MSM (those who self-label as heterosexual or who hide their same-sex sexual attraction from family, friends, acquaintances, or a female romantic partner) differ to open MSM in how they behave on gay chat and dating sites and in offline gay venues. Drawing on a survey of 12,002 MSM, we show that hidden MSM tend to mask their identity on gay chat and dating sites while avoiding offline gay venues...
October 18, 2016: Journal of Homosexuality
David J Brennan, Greta R Bauer, Kaitlin Bradley, Oth Vilaythong Tran
OBJECTIVES: Research on sexual minority men (gay, bisexual and other men who have sex with men) was examined with regard to the measures of sexual orientation used, the methods of research, and the main health outcomes under study. METHODS: We conducted a systematic review of English-language quantitative studies of the health of sexual minority men published in 2010 (n = 250). RESULTS: This snapshot of the literature revealed that research on sexual minority men overwhelmingly focused on HIV, STIs, and sexual health for which sexual orientation was most commonly defined behaviorally...
October 18, 2016: Journal of Homosexuality
Gülşah Kemer, Ezgi Toplu Demirtaş, Amber L Pope, Esra Ummak
The aim of the current study was to examine the psychometric properties of the Lesbian, Gay, and Bisexual Identity Scale (LGBIS; Mohr & Kendra, 2011) in a Turkish sample. Three hundred and ten LGB individuals participated and completed the Turkish version of the LGBIS (LGBIS-TR) along with the Satisfaction with Life, Positive and Negative Affect, and Self-Compassion Scales. Confirmatory factor analysis results yielded a good-fit for eight subscales of the LGBIS-TR. We also obtained satisfactory criterion validity and internal consistency reliability...
October 18, 2016: Journal of Homosexuality
Betty Ferrell, Elaine Wittenberg, Vanessa Battista, Gay Walker
OBJECTIVE: The goal of this study was to explore nurse experiences in communication with children about spiritual topics in order to develop training in this area. BACKGROUND: Although spiritual care is essential in pediatric palliative care, few providers receive training about communication with ill children about spirituality. METHODS: Researchers developed a brief survey to prompt nurses to reflect on pediatric palliative care experiences that included spiritual discussions...
October 18, 2016: Journal of Palliative Medicine
Ritch C Savin-Williams, Brian M Cash, Mark McCormack, Gerulf Rieger
This exploratory study assessed physiological, behavioral, and self-report measures of sexual and romantic indicators of sexual orientation identities among young men (mean age = 21.9 years) with predominant same-sex sexual and romantic interests: those who described themselves as bisexual leaning gay (n = 11), mostly gay (n = 17), and gay (n = 47). Although they were not significantly distinguishable based on physiological (pupil dilation) responses to nude stimuli, on behavioral and self-report measures a descending linear trend toward the less preferred sex (female) was significant regarding sexual attraction, fantasy, genital contact, infatuation, romantic relationship, sex appeal, and gazing time to the porn stimuli...
October 17, 2016: Archives of Sexual Behavior
Christina Dyar, Brian A Feinstein, Nicholas R Eaton, Bonita London
The negative impact of discrimination on mental health among lesbian, gay, and bisexual populations has been well documented. However, the possible mediating roles of sexual orientation rejection sensitivity and rejection-based proximal stress in the association between discrimination and internalizing symptoms remain unclear. Rejection-based proximal stress is a subset of proximal stressors that are theorized to arise from concerns about and expectations of sexual orientation-based rejection and discrimination...
October 17, 2016: Archives of Sexual Behavior
Tyrel J Starks, Michael A Castro, Juan P Castiblanco, Brett M Millar
The existing literature has identified that beliefs about the interpersonal meaning of condom use are a significant predictor of condomless anal sex (CAS). Some have suggested that condom use in this context may function as a form of nonverbal communication. This study utilized attachment theory as a framework and tested a hypothesized model linking adult attachment to CAS through communication skills and condom expectancies. An online survey was completed by 122 single, HIV-negative gay and bisexual (GB) men living in the U...
October 17, 2016: Archives of Sexual Behavior
Diane J Davies, Jon R Heylings, Heather Gayes, Timothy J McCarthy, M Catherine Mack
A new in vitro model based on the electrical resistance properties of the skin barrier has been established in this laboratory. The model utilises a tape stripping procedure in dermatomed pig skin that removes a specific proportion of the stratum corneum, mimicking impaired barrier function observed in humans with damaged skin. The skin penetration and distribution of chemicals with differing physicochemical properties, namely; Benzoic acid, 3-Aminophenol, Caffeine and Sucrose has been assessed in this model...
October 14, 2016: Toxicology in Vitro: An International Journal Published in Association with BIBRA
Kerstin Gerst Emerson, Jennifer Gay
The goals of this study were 1) to test the relative contribution of light-intensity and moderate-to-vigorous intensity physical activity (MVPA) to Cardiovascular Disease (CVD) risk in older adults, and 2) to examine the influence of ethnicity. We used pooled data from the 2003-2004 and 2005-2006 waves of the National Health and Nutritional Examination Survey (NHANES). The sample consisted of 1,171 White, Black and Mexican American adults aged 65 and older. Using ordinary least squares regression, we showed no statistically significant relationship between lower CVD risk with light intensity activity...
October 13, 2016: Journal of Aging and Physical Activity
Christi R McGeorge, Thomas Stone Carlson, Candice A Maier
The purpose of this study was to explore (a) faculty members' beliefs about the ethics of reparative therapy and referring lesbian, gay, and bisexual (LGB) clients, (b) course content related to reparative therapy and referral of LGB clients, and (c) positions taken by programs associated with reparative therapy and referral of LGB clients. A total of 117 faculty members from accredited family therapy programs completed an online survey for this study. While the vast majority of faculty members reported that reparative therapy is unethical, there was less agreement related to the ethics of referring LGB clients, which may highlight the need for clearer ethical guidelines to regulate this potentially harmful practice...
October 17, 2016: Journal of Marital and Family Therapy
Charles Furlotte, James W Gladstone, Robert F Cosby, Kerri-Ann Fitzgerald
This qualitative study describes expectations, concerns, and needs regarding long-term care (LTC) homes and home care services of 12 older lesbian and gay couples living in Canada. Our findings reflect four major themes: discrimination, identity, expenditure of energy, and nuanced care. Discrimination involved concerns about covert discrimination; loss of social buffers as one ages; and diminished ability to advocate for oneself and one's partner. Identity involved anticipated risk over disclosing one's sexual identity; the importance of being identified within a coupled relationship; and the importance of access to reference groups of other gay seniors...
October 17, 2016: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
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