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https://www.readbyqxmd.com/read/29775988/effects-of-different-resistance-training-frequencies-on-fat-in-overweight-obese-older-women
#1
Edilaine F Cavalcante, Alex S Ribeiro, Matheus A do Nascimento, Analiza M Silva, Crisieli M Tomeleri, Hellen C G Nabuco, Fábio L C Pina, Jerry L Mayhew, Marzo E Da Silva-Grigoletto, Danilo R P da Silva, Steven J Fleck, Edilson S Cyrino
AIM: This study compared the effect of different resistance training (RT) frequencies on total, android, gynoid and trunk body fat in overweight/obese older women. METHODS: Fifty-seven overweight/obese older women (66.9±5.3 years and 39.9±4.9% body fat) were randomly assigned to one of three groups: a group performing RT twice a week (G2X), a group performing RT three times a week (G3X), or a non-exercise control group (CG). Both training groups performed the same 12-week RT program consisting of 8 exercises that trained all major muscle groups...
May 18, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29774118/proteomic-profiling-of-skeletal-and-cardiac-muscle-in-cancer-cachexia-alterations-in-sarcomeric-and-mitochondrial-protein-expression
#2
Angie M Y Shum, Anne Poljak, Nicholas L Bentley, Nigel Turner, Timothy C Tan, Patsie Polly
Background: Cancer cachexia is observed in more than 50% of advanced cancer patients, and impairs quality of life and prognosis. A variety of pathways are likely to be dysregulated. Hence, a broad-spectrum understanding of the disease process is best achieved by a discovery based approach such as proteomics. Results: More than 300 proteins were identified with > 95% confidence in correct sequence identification, of which 5-10% were significantly differentially expressed in cachectic tissues ( p -value of 0...
April 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/29772529/microbial-bio-fuels-a-solution-to-carbon-emissions-and-energy-crisis
#3
Arun Kumar, Sumit Kaushal, Shubhini A Saraf, Jay Shankar Singh
Increasing energy demand, limited fossil fuel resources and climate change have prompted development of alternative sustainable and economical fuel resources such as crop-based bio-ethanol and bio-diesel. However, there is concern over use of arable land that is used for food agriculture for creation of biofuel. Thus, there is a renewed interest in the use of microbes particularly microalgae for bio-fuel production. Microbes such as micro-algae and cyanobacteria that are used for biofuel production also produce other bioactive compounds under stressed conditions...
June 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/29772439/long-noncoding-rna-meg3-inhibits-proliferation-of-chronic-myeloid-leukemia-cells-by-sponging-microrna21
#4
Ziye Li, Lin Yang, Xiaojun Liu, Ziyuan Nie, Jianmin Luo
The long noncoding RNA (lnc) maternally expressed 3 (MEG3) is downregulated in many types of cancers. However, the relationship between lncRNA MEG3, microRNA-21 (miR-21) and chronic myeloid leukemia (CML) blast crisis is unknown. This study examined bone marrow samples from 40 CML patients and 10 healthy donors. Proliferation and apoptosis assays, real-time polymerase chain reaction (PCR), bisulfite sequencing PCR, Western blotting, luciferase assay, RNA pull-down, RNA immunoprecipitation (RIP), co-immunoprecipitation (CoIP) and Chromatin immunoprecipitation (ChIP) were performed...
May 14, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29771757/teaching-mental-health-first-aid-in-the-school-setting-a-novel-approach-to-improving-outcomes-for-common-adolescent-mental-disorders
#5
Laura M Hart, Georgina R Cox, Lucy Lees
PURPOSE OF REVIEW: Common adolescent mental disorders, such as depression, often go untreated and severely impact health and educational outcomes. The purpose of this review is to describe what is currently known about school-based mental health interventions and to describe a new intervention, Mental Health First Aid training. RECENT FINDINGS: Universal and selective prevention and treatment programmes have been widely evaluated, though population-level dissemination remains elusive...
May 15, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29771745/national-institute-on-drug-abuse-international-program-improving-opioid-use-disorder-treatment-through-international-research-training
#6
Steven W Gust, Judy McCormally
PURPOSE OF REVIEW: For more than 25 years, the National Institute on Drug Abuse (NIDA) has supported research-training programs, establishing a global research network and expanding the knowledge base on substance use disorders. International research to inform approaches to opioid addiction is particularly important and relevant to the United States, where opioid misuse, addiction, and overdose constitute an emerging public health crisis. This article summarizes the NIDA International Program and illustrates its impact by reviewing recent articles about treatment approaches for opioid use disorders (OUD)...
May 15, 2018: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29771554/perceived-crisis-and-reforms-issues-explanations-and-remedies
#7
Paul De Boeck, Minjeong Jeon
An overview and discussion is made of the perceived replication crisis in terms of end problems, explanations, and remedies. Following a discussion of a published large-scale replication study and a review of the meta-analysis literature, we come to the conclusion that many effects are small and that on average the variance of the effects is roughly 10% to 25% of the population variance, most likely because of context dependencies. The proposed explanations such as questionable and suboptimal research practices (low power, poor measurement quality, and the use of NHST) are discussed, as well as more distal explanatory factors such as journals, funding agencies, and institutions...
May 17, 2018: Psychological Bulletin
https://www.readbyqxmd.com/read/29770727/a-survival-analysis-of-the-last-great-european-plagues-the-case-of-nonantola-northern-italy-in-1630
#8
Guido Alfani, Marco Bonetti
This paper develops the first survival analysis of a large-scale mortality crisis caused by plague. For the time-to-event analyses we used the Cox proportional hazards regression model. Our case study is the town of Nonantola during the 1630 plague, which was probably the worst to affect Italy since the Black Death. Individual risk of death did not depend on sex, grew with age (peaking at ages 40-60 and then declining), was not affected by socio-economic status, and was positively associated with household size...
May 17, 2018: Population Studies
https://www.readbyqxmd.com/read/29770417/single-layer-znmn-2-m-si-ge-sn-zinc-nitrides-as-promising-photocatalysts
#9
Yujie Bai, Gaixia Luo, Lijuan Meng, Qinfang Zhang, Ning Xu, Haiyang Zhang, Xiuqiang Wu, Fanjie Kong, Baolin Wang
Searching for two-dimensional semiconductor materials that are suitable for visible-light photocatalytic water splitting provides a sustainable solution to deal with the future energy crisis and environmental problems. Herein, based on first-principles calculations, single-layer ZnMN2 (M = Si, Ge, Sn) zinc nitrides are proposed as efficient photocatalysts for water splitting. Stability analyses show that the single-layer ZnMN2 zinc nitrides exhibit energetic and dynamical stability. The electronic properties reveal that all of the single-layer ZnMN2 zinc nitrides are semiconductors...
May 17, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29770106/perceptions-about-authentic-leadership-development-south-african-occupational-therapy-students-camp-experience
#10
Fatima Hendricks, Susan Toth-Cohen
Background: Twenty-three years into democracy, concern is deepening regarding the slow progress of Occupational Therapy (OT) in South Africa, especially with regard to diversity and inclusion within OT. Methods: This study explores authentic leadership development primarily among Black OT students attending a pilot Occupational Therapy Association of South Africa (OTASA) National Student Leadership Camp. It seeks to ascertain their perceptions on leadership and leadership development...
2018: Occupational Therapy International
https://www.readbyqxmd.com/read/29770095/zika-virus-where-to-from-here
#11
EDITORIAL
P K Muchaal
After the waves of reported cases of infection with Zika virus swept across the Americas in 2015-16, the overall transmission of the virus in the Western Hemisphere declined in 2017. Between June 8 and August 31, 2017, only 16 new cases of Zika virus infection, all travel-related, were reported in Canada. This represents an 88% reduction in the cases recorded during the same time frame in 2016. Herd immunity undoubtedly constrains the transmission of the virus in endemic regions. However, while most countries in the Americas are no longer observing continuous transmission in the form of sustained increases over time, some areas are experiencing a notable resurgence...
January 4, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29769367/similarities-between-military-and-medical-service-stigma-of-seeking-mental-health-assistance
#12
EDITORIAL
Fergus Gardiner, E C Gardiner
Studies have identified that there are many barriers to treatment of mental health illnesses in military populations, including the negative-associated stigma. One such barrier includes perceptions of weakness, leading to concerns about leadership and competency and being seen as malingering. Furthermore, similarities can be seen in civilian health professionals, where concerns of negative perceptions can limit reporting and treatment of mental health illnesses. Despite the frequency of stressful events, military and health professionals do not become immune to stress and are often ill prepared to cope with acute stressors that can often build on each other until emotional exhaustion and/or crisis point...
May 16, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29769233/muscle-tensions-merge-to-cause-a-dna-replication-crisis
#13
Daniel Brayson, Chin Yee Ho, Catherine M Shanahan
In this issue, Wang et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201708137) show that disruption to different mechanical domains of muscle cells converge at the linker of nucleoskeleton to cytoskeleton complex to affect DNA endoreplication potentially via barrier to autointegration factor-mediated epigenetic mechanisms.
May 16, 2018: Journal of Cell Biology
https://www.readbyqxmd.com/read/29768607/-the-medicalization-of-life-hybrids-against-the-dichotomy-nature-culture
#14
Anahi Sy
This paper aims to analyze the process of medicalization in current societies, starting from the description of the way in which medicine gradually appropriated various aspects of everyday life that were once part of the life cycle of people. At the theoretical level, we are based on authors such as Descola and Latour, who problematize the dichotomy between Nature and Culture, and propose the need to think from a superior episteme. Methodologically, this theoretical proposal enables an analysis of the medicalization that can illuminate what is hidden in the discourse and biomedical practices: the sociocultural, political and economic processes that are part of these "objects" of Medicine...
May 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29767842/more-than-just-co-2-recycling-corticular-photosynthesis-as-a-mechanism-to-reduce-the-risk-of-an-energy-crisis-induced-by-low-oxygen
#15
Christiane Wittmann, Hardy Pfanz
Reassimilation of internal CO2 via corticular photosynthesis (PScort ) has an important effect on the carbon economy of trees. However, little is known about its role as a source of O2 supply to the stem parenchyma and its implications in consumption and movement of O2 within trees. PScort of young Populus nigra (black poplar) trees was investigated by combining optical micro-optode measurements with monitoring of stem chlorophyll fluorescence. During times of zero sap flow in spring, stem oxygen concentrations (cO2 ) exhibited large temporal changes...
May 16, 2018: New Phytologist
https://www.readbyqxmd.com/read/29767481/supporting-care-home-staff-to-manage-residents-care-safely-and-avoid-admissions
#16
Susan Wills, Dena Ross
The community matron care homes team (CHT) was set up in Sandwell, West Midlands in 2011 to support care home staff to manage residents' care safely and reduce unplanned and/or avoidable use of acute health services. The service was reviewed in 2015 and attention focused on care homes with the highest levels of hospital use and emergency 999 services. Working with these care home staff and health professionals, a training and education opportunity to aid staff to manage residents in crisis was sourced, organised and implemented...
May 16, 2018: Nursing Older People
https://www.readbyqxmd.com/read/29765399/a-seasonal-time-series-model-based-on-gene-expression-programming-for-predicting-financial-distress
#17
Ching-Hsue Cheng, Chia-Pang Chan, Jun-He Yang
The issue of financial distress prediction plays an important and challenging research topic in the financial field. Currently, there have been many methods for predicting firm bankruptcy and financial crisis, including the artificial intelligence and the traditional statistical methods, and the past studies have shown that the prediction result of the artificial intelligence method is better than the traditional statistical method. Financial statements are quarterly reports; hence, the financial crisis of companies is seasonal time-series data, and the attribute data affecting the financial distress of companies is nonlinear and nonstationary time-series data with fluctuations...
2018: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/29765356/soluble-and-cell-cell-mediated-drivers-of-proteasome-inhibitor-resistance-in-multiple-myeloma
#18
REVIEW
Mariah L Farrell, Michaela R Reagan
It is becoming clear that myeloma cell-induced disruption of the highly organized bone marrow components (both cellular and extracellular) results in destruction of the marrow and support for multiple myeloma (MM) cell proliferation, survival, migration, and drug resistance. Since the first phase I clinical trial on bortezomib was published 15 years ago, proteasome inhibitors (PIs) have become increasingly common for treatment of MM and are currently an essential part of any anti-myeloma combination therapy...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29764917/the-path-to-victory-a-beginner-s-guide-to-success-using-commercial-research-antibodies
#19
REVIEW
Simon L Goodman
Commercial research antibodies are crucial tools in modern cell biology and biochemistry. In the USA some $2 billion a year are spent on them, but many are apparently not fit-for-purpose, and this may contribute to the 'reproducibility crisis' in biological sciences. Inadequate antibody validation and characterization, lack of user awareness, and occasional incompetence amongst suppliers have had immense scientific and personal costs. In this Opinion, I suggest some paths to make the use of these vital tools more successful...
May 15, 2018: Journal of Cell Science
https://www.readbyqxmd.com/read/29764495/cancer-mortality-in-serbia-1991-2015-an-age-period-cohort-and-joinpoint-regression-analysis
#20
Milena Ilic, Irena Ilic
BACKGROUND: As the result of dramatic political changes, civil wars, and a long-term refugee crisis from the end of the last to beginning of this century, the population of Serbia has experienced significant health problems. The aim of this study was to assess cancer mortality trends in Serbia. METHODS: This nationwide study was carried out to analyze cancer mortality in Serbia during 1991-2015 using official data. The age-standardized mortality rates (per 100,000) were calculated by direct standardization, using the world standard population by Segi...
April 10, 2018: Cancer communications
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