keyword
MENU ▼
Read by QxMD icon Read
search

Premenopausal

keyword
https://www.readbyqxmd.com/read/29440863/adverse-effects-with-finasteride-5-mg-day-for-patterned-hair-loss-in-premenopausal-women
#1
Rui Oliveira-Soares, Marisa C André, Miguel Peres-Correia
No abstract text is available yet for this article.
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29437023/serum-dhea-s-testosterone-and-cortisol-levels-in-female-patients-with-schizophrenia
#2
Suheyla Dogan Bulut, Serdar Bulut, Ayse G Gundogmus, Cigdem Aydemir
OBJECTIVE: Recent studies have shown that sex hormones play a role in the development of schizophrenia and the severity of disease symptoms. However, study results have been inconsistent. This study compares the relationship between the severity of disease symptoms and levels of testosterone, and DHEA-S and cortisol in premenopausal female patients with schizophrenia and a matched group of healthy controls. METHODS: The study sample included 32 women who were diagnosed as having schizophrenia according to DSM-IV TR criteria, and 32 age- and sex-matched healthy controls...
February 11, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29435713/incidence-of-infusion-hypersensitivity-reaction-after-withholding-dexamethasone-premedication-in-early-breast-cancer-patients-not-experiencing-two-previous-cycles-of-infusion-hypersensitivity-reaction-for-weekly-paclitaxel-chemotherapy
#3
Napa Parinyanitikul, Walailuk Tanpipattanakul, Nattaya Poovorawan, Thanapoom Rattananupong, Poranee Laoitthi, Piyada Sithidetphaiboon, Suebpong Thanasanvimon, Virote Sriuranpong
BACKGROUND: Premedication with dexamethasone is an essential part of the prevention of hypersensitivity reaction (HSR) associated with taxane administration. However, the possibility of stopping dexamethasone premedication has been investigated in previous studies to reduce the steroid's adverse events; however, either the result or the particular protocol was limited. Thus, our study aimed to evaluate the incidence of HSR after dexamethasone premedication discontinuation after lack of HSR in two previous weekly paclitaxel infusions...
February 12, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29434315/association-of-gut-microbial-communities-with-plasma-lipopolysaccharide-binding-protein-lbp-in-premenopausal-women
#4
Jessica S Citronberg, Keith R Curtis, Emily White, Polly A Newcomb, Katherine Newton, Charlotte Atkinson, Xiaoling Song, Johanna W Lampe, Meredith Aj Hullar
The mechanisms by which obesity increases cancer risk are unclear, but some lines of evidence suggest that gut microbial communities (GMC) may contribute to chronic inflammation in obese individuals through raised systemic levels of lipopolysaccharides (LPS). We evaluated associations of the GMC in stool with plasma LPS-binding protein (LBP, a measure of LPS) and C-reactive protein (CRP) concentrations in 110 premenopausal women in the United States. Diet was assessed using 3-day food records and GMCs were evaluated using pyrosequencing of the 16S rRNA gene...
February 12, 2018: ISME Journal
https://www.readbyqxmd.com/read/29433827/adipocytokines-and-breast-cancer
#5
REVIEW
Jiajia Li, Xianghui Han
A substantial number of studies have revealed that a growing list of cancers might be influenced by obesity. In this regard, one of the most prominent and well-characterized cancers is breast cancer, the leading cause of cancer death among women. Obesity is associated with an increased risk for the occurrence and development of breast cancer particular in postmenopausal women. Moreover, the relationship between adiposity and breast cancer risk is complex, with associations that differ depending on when body size is assessed (eg, premenopausal vs postmenopausal obesity) and when breast cancer is diagnosed (ie, premenopausal vs postmenopausal disease)...
January 8, 2018: Current Problems in Cancer
https://www.readbyqxmd.com/read/29428305/high-molecular-weight-adiponectin-is-inversely-associated-with-sympathetic-activity-in-polycystic-ovary-syndrome
#6
Soulmaz Shorakae, Sally K Abell, Danielle S Hiam, Elisabeth A Lambert, Nina Eikelis, Eveline Jona, Carolina Ika Sari, Nigel K Stepto, Gavin W Lambert, Barbora de Courten, Helena J Teede
OBJECTIVE: To examine the role of high-molecular-weight (HMW) adiponectin and its relationship to sympathetic activity in women with polycystic ovary syndrome (PCOS). DESIGN: Cross sectional study using biobanked samples. SETTING: Not applicable. PATIENT(S): Premenopausal women with PCOS (n = 46, Rotterdam diagnostic criteria) and without PCOS (n = 22). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): High-molecular-weight adiponectin levels with secondary outcomes of sympathetic activity and leptin levels...
February 7, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29426984/breast-cancer-subtype-and-survival-by-parity-and-time-since-last-birth
#7
H De Mulder, A Laenen, H Wildiers, K Punie, A Poppe, C Remmerie, H Lefrère, I Nevelsteen, A Smeets, E Van Nieuwenhuysen, S Han, E Van Limbergen, G Floris, I Vergote, P Neven
BACKGROUND: Pregnancy affects breast cancer risk but how it affects the subtype and prognosis remain controversial. We studied the effect of parity and time since last birth on breast cancer subtype and outcome. PATIENTS AND METHODS: We conducted a retrospective multivariate cohort study including all premenopausal women with early breast cancer aged ≤ 50 years (N = 1306) at diagnosis at the University Hospitals Leuven (Jan. 2000-Dec. 2009). Primary study endpoints were the breast cancer subtype, disease-free survival, and distant disease-free survival by parity and time since last birth...
February 10, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29424790/differences-in-local-and-systemic-tenofovir-pharmacokinetics-among-premenopausal-versus-postmenopausal-women-exposed-to-tenofovir-1-vaginal-gel
#8
Andrea Ries Thurman, Neelima Chandra, Nazita Yousefieh, Thomas Kimble, Sharon M Anderson, Mackenzie Cottrell, Craig Sykes, Angela Kashuba, Jill L Schwartz, Gustavo F Doncel
OBJECTIVE: We describe and compare the local and systemic pharmacokinetics (PK) of tenofovir (TFV) and TFV-diphosphate (TFV-DP) in healthy premenopausal (PRE) and postmenopausal (POST) women using TFV 1% gel and correlate local PK to other mucosal endpoints. METHODS: PRE (n = 20) and POST (n = 17) women used two doses of TFV 1% vaginal gel, separated by 2 hours. Blood and cervico-vaginal (CV) samples were obtained 3 and 23 hours after the second dose. PRE women used gel in the follicular and luteal phases of the menstrual cycle...
February 7, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29423901/impact-of-physiological-hormonal-fluctuations-on-18f-fluorodeoxyglucose-uptake-in-breast-cancer
#9
Kanae K Miyake, Yuji Nakamoto, Shigehira Saji, Tomoharu Sugie, Kensuke Kurihara, Shotaro Kanao, Debra M Ikeda, Masakazu Toi, Kaori Togashi
PURPOSE: Premenopausal physiologic steroid levels change cyclically, in contrast to steady state low levels seen in postmenopausal patients. The purpose of this study was to evaluate whether 18F-fluorodeoxyglucose (18F-FDG) uptake in breast cancer is influenced by physiological hormonal fluctuations. METHODS: A total of 160 primary invasive breast cancers from 155 females (54 premenopausal, 101 postmenopausal) who underwent 18F-FDG positron emission tomography/computed tomography before therapy were retrospectively analyzed...
February 8, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29423438/breast-cancer-risk-factors-and-mammographic-density-among-high-risk-women-in-urban-china
#10
Hyuna Sung, Jiansong Ren, Jing Li, Ruth M Pfeiffer, Yong Wang, Jennifer L Guida, Yi Fang, Jufang Shi, Kai Zhang, Ni Li, Shen Wang, Luopei Wei, Nan Hu, Gretchen L Gierach, Min Dai, Xiaohong R Yang, Jie He
Elevated mammographic density (MD) is an established breast cancer risk factor. Studies examining relationships between MD and breast cancer risk factors are limited in China, where established breast cancer risk factors are less prevalent but dense breasts are more prevalent than Western countries. This study included 11,478 women (45-69 years; 36% premenopausal) participating in an ongoing national cancer screening program in 11 urban provinces in China and predicted as having high-risk for breast cancer...
2018: NPJ Breast Cancer
https://www.readbyqxmd.com/read/29423115/association-between-cyp17-t-34c-rs743572-and-breast-cancer-risk
#11
Jing Sun, Hong Zhang, Meiyan Gao, Zhishu Tang, Dongyan Guo, Xiaofei Zhang, Zhu Wang, Ruiping Li, Yan Liu, Wansen Sun, Xi Sun
Association between CYP17 T-34C (rs743572) polymorphism and breast cancer (BC) risk was controversial. In order to derive a more definitive conclusion, we performed this meta-analysis. We searched in the databases of PubMed, EMBASE and Cochrane for eligible publications. Pooled odds ratios (ORs) with 95% confidence intervals (95% CIs) were used to assess the strength of association between CYP17 T-34C polymorphism and breast cancer risk. Forty-nine studies involving 2,7104 cases and 3,4218 control subjects were included in this meta-analysis...
January 9, 2018: Oncotarget
https://www.readbyqxmd.com/read/29422346/bone-loss-in-women-with-brca1-and-brca2-mutations
#12
C Bethan Powell, Amy Alabaster, Nicole Stoller, Mary Anne Armstrong, Chelsea Salyer, Isabella Hamilton, Tina Raine-Bennett
OBJECTIVE: Estimate the prevalence and identify risk factors for bone loss in women with BRCA mutations. METHODS: Women, age 40 and older, with BRCA mutations identified from the Breast Cancer Surveillance database at Kaiser Permanente Northern California were invited to participate and undergo a dual-energy x-ray absorptiometry scan to assess for bone loss (osteopenia or osteoporosis). Multivariable logistic regression analysis was performed to assess clinical factors associated with bone loss...
February 5, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29420395/ulipristal-acetate-for-treatment-of-symptomatic-uterine-leiomyomas-a-randomized-controlled-trial
#13
James A Simon, William Catherino, James H Segars, Rick E Blakesley, Anna Chan, Vilma Sniukiene, Ayman Al-Hendy
OBJECTIVE: To assess efficacy and tolerability of ulipristal acetate, a selective progesterone receptor modulator, for treatment of symptomatic uterine leiomyomas. METHODS: This phase 3, double-blind, placebo-controlled study enrolled premenopausal women (aged 18-50 years) with abnormal uterine bleeding, one or more discrete leiomyomas, and uterine size 20 weeks of gestation or less. Patients were randomized 1:1:1 to 5 mg ulipristal, 10 mg ulipristal, or placebo once daily for 12 weeks followed by 12-week drug-free follow-up...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29416771/menopause-and-adipose-tissue-mir-19a-3p-is-sensitive-to-hormonal-replacement
#14
Reeta Kangas, Cristina Morsiani, Grazia Pizza, Catia Lanzarini, Pauliina Aukee, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen, Eija K Laakkonen, Miriam Capri
Tissue-specific effects of 17β-estradiol are delivered via both estrogen receptors and microRNAs (miRs). Menopause is known to affect the whole-body fat distribution in women. This investigation aimed at identifying menopause- and hormone replacement therapy (HRT)-associated miR profiles and miR targets in subcutaneous abdominal adipose tissue and serum from the same women. A discovery phase using array technology was performed in 13 women, including monozygotic twin pairs discordant for HRT and premenopausal young controls...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29410349/non-targeted-profiling-of-circulating-micrornas-in-women-with-polycystic-ovary-syndrome-pcos-effects-of-obesity-and-sex-hormones
#15
Mora Murri, María Insenser, Elena Fernández-Durán, José L San-Millán, Manuel Luque-Ramírez, Héctor F Escobar-Morreale
PURPOSE: Circulating micro-ribonucleic acids (miRNAs) are small noncoding RNA molecules that influence gene transcription. We conducted the present profiling study to characterize the expression of circulating miRNAs in lean and obese patients with polycystic ovary syndrome (PCOS), the most common endocrine and metabolic disorder in premenopausal women. BASIC PROCEDURES: We selected 11 control women, 12 patients with PCOS and 12 men so that they were similar in terms of body mass index...
February 1, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29410107/laparoscopic-vs-transvaginal-cuff-closure-after-total-laparoscopic-hysterectomy-a-randomized-trial-by-the-italian-society-of-gynecologic-endoscopy
#16
Stefano Uccella, Mario Malzoni, Antonella Cromi, Renato Seracchioli, Giuseppe Ciravolo, Francesco Fanfani, Fevzi Shakir, Salvatore Gueli Alletti, Francesco Legge, Roberto Berretta, Giacomo Corrado, Lucia Casarella, Paolo Donarini, Margherita Zanello, Emanuele Perrone, Baldo Gisone, Enrico Vizza, Giovanni Scambia, Fabio Ghezzi
BACKGROUND: Vaginal cuff dehiscence following hysterectomy is considered an infrequent but potentially devastating complication. Different possible techniques for cuff closure have been proposed to reduce this threatening adverse event. OBJECTIVE: Aim of the present randomized study has been to compare laparoscopic and transvaginal suture of the vaginal vault at the end of a total laparoscopic hysterectomy (TLH), in terms of incidence of vaginal dehiscence and vaginal cuff complications...
January 31, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29409816/mutational-analysis-of-rad51c-and-rad51d-genes-in-hereditary-breast-and-ovarian-cancer-families-from-murcia-southeastern-spain
#17
Ana Isabel Sánchez-Bermúdez, Ma Desamparados Sarabia-Meseguer, Ángeles García-Aliaga, Miguel Marín-Vera, José Antonio Macías-Cerrolaza, Pilar Sánchez Henaréjos, Verónica Guardiola-Castillo, Francisco Ayala-de la Peña, José Luis Alonso-Romero, José Antonio Noguera-Velasco, Francisco Ruiz-Espejo
RAD51C and RAD51D have been defined as susceptibility genes for hereditary breast and ovarian cancer syndrome in several studies. In the present study, a mutation analysis of these genes was performed on non BRCA1/2 families. RAD51C and RAD51D genes were analyzed in 141 and 77 families, respectively. The analysis included direct sequencing and multiple ligation probe analysis. The RAD51C pathogenic variant c.404G > A was identified in a breast and ovarian cancer family (0.7%), while the RAD51D pathogenic variant c...
January 31, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29409520/factors-associated-with-menstrual-cycle-irregularity-and-menopause
#18
Jinju Bae, Susan Park, Jin-Won Kwon
BACKGROUND: A regular menstrual cycle is an important indicator of a healthy reproductive system. Previous studies reported obesity, stress, and smoking as the factors that are associated with irregular menstruation and early menopause. However, the integrative effects of these modifiable risk factors have not been fully understood. This study aimed to investigate the modifiable risk factors of menstrual cycle irregularity and premature menopause, as well as their individual and combined effects among adult women in Korea...
February 6, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29408747/risk-factors-for-ovarian-involvement-in-young-and-premenopausal-endometrioid-endometrial-cancer-patients
#19
Jun Li, Qin Zhu, Bingyi Yang, Chengcheng Ning, Xiaoxia Liu, Xuezhen Luo, Xiaojun Chen
OBJECTIVE: This study aimed to investigate the incidence of ovarian malignant involvement in young and premenopausal endometrioid endometrial cancer and study the possible risk factors. METHODS: Premenopausal patients 45 years of age or younger with endometrioid endometrial cancer treated at the OB/GYN Hospital of Fudan University between 2009 and 2013 were identified. The incidence of ovarian malignant involvement in young and premenopausal endometrioid endometrial cancer patients were calculated and the possible risk factors were investigated...
January 31, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29404807/physical-activity-during-adolescence-and-young-adulthood-and-the-risk-of-breast-cancer-in-brca1-and-brca2-mutation-carriers
#20
Jacqueline Lammert, Jan Lubinski, Jacek Gronwald, Tomasz Huzarski, Susan Armel, Andrea Eisen, Wendy S Meschino, Henry T Lynch, Carrie Snyder, Charis Eng, Olufunmilayo I Olopade, Ophira Ginsburg, William D Foulkes, Christine Elser, Stephanie A Cohen, Marion Kiechle, Steven A Narod, Joanne Kotsopoulos
BACKGROUND: Physical activity is inversely associated with the risk of breast cancer among women in the general population. It is not clear whether or not physical activity is associated with the risk of BRCA-associated breast cancer. METHODS: We conducted a case-control study of 443 matched pairs of BRCA mutation carriers to evaluate the association between physical activity and breast cancer risk. Moderate and vigorous physical activities at ages 12-13, ages 14-17, ages 18-22, ages 23-29 and ages 30-34 were determined using the Nurses' Health Study II Physical Activity Questionnaire...
February 5, 2018: Breast Cancer Research and Treatment
keyword
keyword
13421
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"