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https://www.readbyqxmd.com/read/29784977/cryptococcus-neoformans-sexual-reproduction-is-controlled-by-a-quorum-sensing-peptide
#1
Xiuyun Tian, Guang-Jun He, Pengjie Hu, Lei Chen, Changyu Tao, Ying-Lu Cui, Lan Shen, Weixin Ke, Haijiao Xu, Youbao Zhao, Qijiang Xu, Fengyan Bai, Bian Wu, Ence Yang, Xiaorong Lin, Linqi Wang
Bacterial quorum sensing is a well-characterized communication system that governs a large variety of collective behaviours. By comparison, quorum sensing regulation in eukaryotic microbes remains poorly understood, especially its functional role in eukaryote-specific behaviours, such as sexual reproduction. Cryptococcus neoformans is a prevalent fungal pathogen that has two defined sexual cycles (bisexual and unisexual) and is a model organism for studying sexual reproduction in fungi. Here, we show that the quorum sensing peptide Qsp1 serves as an important signalling molecule for both forms of sexual reproduction...
May 21, 2018: Nature Microbiology
https://www.readbyqxmd.com/read/29784522/expanding-couples-based-hiv-testing-and-counseling-in-the-united-states-findings-from-a-nationwide-online-survey-of-partnered-adults
#2
Ji-Young Lee, Jason W Mitchell
Couples-based HIV testing and counseling (CHTC) is currently available only for gay male couples in the United States, but other types of couples could benefit from this service. Our cross-sectional, online study collected data from 536 partnered adults to assess interest in using CHTC and associated factors. Adjusted odds ratios were calculated with ordinal logistic regression to analyze factors associated with greater interest in using CHTC. Most participants were female, White, non-Hispanic, and/or students who were dating exclusively and sexually active...
April 23, 2018: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29782296/sexual-behaviors-attitudes-and-knowledge-about-sexually-transmitted-infections-a-cross-sectional-study-in-romania
#3
Alecsandra Iulia Grad, Simona Corina Senilă, Rodica Cosgarea, Alexandru Dumitru Tataru, Stefan Cristian Vesa, Mihaela Laura Vica, Horea Vladi Matei, Loredana Ungureanu
Sexually transmitted infections (STIs) are serious public health problems. Little is known about sex knowledge, attitudes, and sexual behaviors among young adults in Romania; an effective preventive campaigns should be based on an appropriate understanding of these factors. The aim of the present study was to obtain data about sexual behavior, attitudes, and knowledge about STIs among university students aged 18-25 in Romania. 3872 persons completed an internet-based questionnaire, advertised on Facebook, regarding sexual behavior, attitudes, and knowledge about STIs from January 28 to February 28, 2016...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29778770/age-related-prevalence-and-twelve-month-incidence-of-illicit-drug-use-in-a-cohort-of-australian-gay-and-bisexual-men-results-from-the-flux-study
#4
Fengyi Jin, Mohamed A Hammoud, Lisa Maher, Louisa Degenhardt, Adam Bourne, Toby Lea, Stefanie Vaccher, Jeffrey Grierson, Bridget Haire, Garrett P Prestage
BACKGROUND: We report prevalence and incidence of drug use initiation in Australian gay and bisexual men (GBM) participating in an online cohort study. METHODS: Between September 2014 and June 2015, 1,710 GBM were enrolled in the Following Lives Undergoing Change Study and followed-up six monthly. Participants were asked about measures of lifetime use at baseline and recent use (last six months) at all visits. Drug use initiation was defined as men who reported having never used a specific drug prior to baseline and reported recent use at follow-up...
May 12, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29775991/redefining-perinatal-experience-a-philosophical-exploration-of-a-hypothetical-case-of-gender-diversity-in-labour-and-birth
#5
Brianna Richardson, Sheri Price, Marsha Campbell-Yeo
OBJECTIVE AND AIMS: Using a queer phenomenological approach, the objective of this philosophical analysis is to explore the transgender experience in highly gendered clinical areas, such as the birth unit, and make recommendations on how to provide perinatal care that is inclusive of gender diversity within these areas. This paper aims to describes a hypothetical clinical experience to provide insight on the institutional barriers that currently exist and to provide nurses and midwives with pragmatic strategies to enhance gender-diverse care in general and gendered clinical areas...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29773663/factors-associated-with-condom-use-and-hiv-testing-among-young-men-who-have-sex-with-men-a-cross-sectional-survey-in-a-random-online-sample-in-sweden
#6
Klara Johansson, Kristina Ingemarsdotter Persson, Charlotte Deogan, Ziad El-Khatib
OBJECTIVES: The objectives are to analyse social determinants of sexual health behaviour (condom use and HIV testing) among young, internet-active, cis men who have sex with men (MSM) in a high-income country. The aspects of sexual health behaviour analysed here are condomless anal intercourse with one or more new or casual partner(s), condomless anal intercourse during the most recent sex with a man and HIV testing. METHODS: A randomised sample of men active on Sweden's main online community for Lesbian, Gay, Bisexual and Trans people responded to an online survey (response rate 19%)...
May 17, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29771782/differential-patterns-of-risk-and-vulnerability-suggest-the-need-for-novel-prevention-strategies-for-black-bisexual-men-in-the-hptn-061-study
#7
Typhanye V Dyer, Maria R Khan, Rotrease Regan, Nina T Harawa, LaRon E Nelson, Leo Wilton, Lei Wang, Lili Peng, San San Ou, Steve Shoptaw
BACKGROUND: Black men who have sex with men (BMSM); some who also have sex with women (BMSMW), account for over 70% of new HIV infections in the US representing an elevated HIV risk in this group, also informing risks for HIV transmission to other BMSM and female sexual partners. SETTINGS: We examined trajectories of self-reported substance use, HIV-related sexual risk behaviors and psychosocial vulnerabilities among BMSMW versus BMSM over a one-year study period...
May 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29770367/engaging-religious-leaders-to-support-hiv-prevention-and-care-for-gays-bisexual-men-and-other-men-who-have-sex-with-men-in-coastal-kenya
#8
Evans Gichuru, Bernadette Kombo, Noni Mumba, Salla Sariola, Eduard J Sanders, Elise M van der Elst
In Kenyan communities, religious leaders are important gatekeepers in matters of health and public morality. In a context that is generally homophobic, religious leaders may aggravate or reduce stigmatization of sexual minorities such as gay and bisexual men, and other men who have sex with men (GBMSM). Literature indicates mixed results in efforts to encourage religious leaders to work effectively and sensitively with issues regarding HIV and sexuality. This paper describes the implementation of an engagement intervention with religious leaders from different denominations, which took place following a homophobic hate attack that was led by local religious leaders, at an HIV research clinic for GBMSM on the Kenyan coast...
2018: Critical Public Health
https://www.readbyqxmd.com/read/29766438/sexual-orientation-differences-in-outpatient-psychiatric-treatment-and-antidepressant-usage-evidence-from-a-population-based-study-of-siblings
#9
Richard Bränström, Mark L Hatzenbuehler, Petter Tinghög, John E Pachankis
In the past two decades, population-based health surveys have begun including measures of sexual orientation, permitting estimates of sexual orientation disparities in psychiatric morbidity and differences in treatment utilization. The present study takes advantage of the high-quality, comprehensive nationwide health registry data available in Sweden to examine whether psychiatric outpatient treatment for various diagnoses and antidepressant medication usage are greater in sexual minority individuals compared to their siblings...
May 15, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29763683/sexual-and-gender-minority-cigarette-smoking-disparities-an-analysis-of-2016-behavioral-risk-factor-surveillance-system-data
#10
Leah Hoffman, Janine Delahanty, Sarah E Johnson, Xiaoquan Zhao
We examined the association between lesbian, gay, bisexual, and transgender (LGBT) identity, cigarette and e-cigarette use, and potential risk factors in the United States. Using data from 198,057 adults in 26 states in the 2016 Behavioral Risk Factor Surveillance System (BRFSS), we estimated the prevalence of cigarette use, e-cigarette use, and potential risk factors by gender identity and sexual identity. Overall and sex-stratified bivariate and multivariate logistic regressions examined whether the relationship between sexual and gender identity and cigarette and e-cigarette use persisted after adjusting for demographics, socio-economic status, and other unhealthy behaviors...
May 12, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29762177/neuropsychological-phenotypes-among-men-with-and-without-hiv-disease-in-the-multicenter-aids-cohort-study
#11
Samantha A Molsberry, Yu Cheng, Lawrence Kingsley, Lisa Jacobson, Andrew J Levine, Eileen Martin, Eric N Miller, Cynthia A Munro, Ann Ragin, Ned Sacktor, James T Becker
OBJECTIVE: Mild forms of HIV-associated neurocognitive disorder (HAND) remain prevalent in the combination anti-retroviral therapy (cART) era. This study's objective was to identify neuropsychological subgroups within the Multicenter AIDS Cohort Study (MACS) based on the participant-based latent structure of cognitive function and to identify factors associated with subgroups. DESIGN: The MACS is a four-site longitudinal study of the natural and treated history of HIV disease among gay and bisexual men...
May 11, 2018: AIDS
https://www.readbyqxmd.com/read/29754596/sharing-solutions-for-a-reasoned-and-evidence-based-response-chemsex-party-and-play-among-gay-and-bisexual-men
#12
Adam Bourne, Jason Ong, Mark Pakianathan
This Special Issue of Sexual Health examines research and healthcare practice relating to sexualised drug use among gay, bisexual and other men who have sex with men (GBMSM), colloquially known as 'chemsex' or 'party and play' (PnP). It draws together evidence relating to the epidemiology, sociology and psychology of chemsex, as well as the policy, community and clinical interventions that are required to ensure men have access to high-quality health care that meets their needs and reduces harm. Findings and discussions within the Issue emphasise the need to sensitively, non-judgementally and meaningfully engage with gay men about their engagement in chemsex in order to help improve their sexual health and wider wellbeing...
April 2018: Sexual Health
https://www.readbyqxmd.com/read/29741980/sexual-orientation-group-differences-in-perceived-stress-and-depressive-symptoms-among-young-adults-in-the-united-states
#13
Evan A Krueger, Ilan H Meyer, Dawn M Upchurch
PURPOSE: Overall, sexual minorities have poorer mental health than heterosexual individuals, and stress is thought to underlie such disparities. However, sexual minorities include both those identifying as lesbian, gay, or bisexual (LGB) and many who do not (e.g., individuals identifying as mostly heterosexual, or as heterosexual but with discordant same-sex attractions or behaviors), and little is known about the mental health or stress experiences of non-LGB identified sexual minorities...
May 9, 2018: LGBT Health
https://www.readbyqxmd.com/read/29734218/depressive-symptoms-and-problematic-alcohol-and-other-substance-use-in-1-476-gay-bisexual-and-other-men-who-have-sex-with-men-at-three-research-sites-in-kenya
#14
Christine Korhonen, Makobu Kimani, Elizabeth Wahome, Fredrick Otieno, Duncan Okall, Robert C Bailey, Gary W Harper, Robert R Lorway, Monika Doshi, John Mathenge, Joshua Kimani, Eduard J Sanders, Susan M Graham
OBJECTIVE: Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS: Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6)...
May 3, 2018: AIDS
https://www.readbyqxmd.com/read/29728348/the-acceptability-and-feasibility-of-implementing-a-bio-behavioral-enhanced-surveillance-tool-for-sexually-transmitted-infections-in-england-mixed-methods-study
#15
Sonali Wayal, David Reid, Paula B Blomquist, Peter Weatherburn, Catherine H Mercer, Gwenda Hughes
BACKGROUND: Sexually transmitted infection (STI) surveillance is vital for tracking the scale and pattern of epidemics; however, it often lacks data on the underlying drivers of STIs. OBJECTIVE: This study aimed to assess the acceptability and feasibility of implementing a bio-behavioral enhanced surveillance tool, comprising a self-administered Web-based survey among sexual health clinic attendees, as well as linking this to their electronic health records (EHR) held in England's national STI surveillance system...
May 4, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29722275/eliminating-hiv-hcv-co-infection-in-gay-and-bisexual-men-is-it-achievable-through-scaling-up-treatment
#16
Rachel Sacks-Davis, Alisa E Pedrana, Nick Scott, Joseph S Doyle, Margaret E Hellard
Broad availability of direct-acting antiviral therapy for hepatitis C virus (HCV) raises the possibility that HCV prevalence and incidence can be reduced through scaling-up treatment, leading to the elimination of HCV. High rates of linkage to HIV care among HIV-infected gay and bisexual men may facilitate high uptake of HCV treatment, possibly making HCV elimination more achievable in this group. Areas covered: This review covers HCV elimination in HIV-infected gay and bisexual men, including epidemiology, spontaneous clearance and long term sequelae in the absence of direct-acting antiviral therapy; direct-acting antiviral therapy uptake and effectiveness in this group; HCV reinfection following successful treatment; and areas for further research...
May 3, 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29720541/risk-of-type-2-diabetes-among-lesbian-bisexual-and-heterosexual-women-findings-from-the-nurses-health-study-ii
#17
Heather L Corliss, Nicole A VanKim, Hee-Jin Jun, S Bryn Austin, Biling Hong, Molin Wang, Frank B Hu
OBJECTIVE: Lesbian and bisexual (LB) women are more likely than heterosexual women to exhibit risk factors for type 2 diabetes, but studies estimating the burden of type 2 diabetes among LB women are uncommon and limited to cross-sectional designs. This study investigated incidence of type 2 diabetes in LB women and heterosexual women in a large, longitudinal U.S. cohort. RESEARCH DESIGN AND METHODS: Women participating in the Nurses' Health Study II ages 24-44 years in 1989 were prospectively followed through 2013...
May 2, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29720151/aids-incidence-trends-at-presentation-and-during-follow-up-among-hiv-at-risk-populations-a-15-year-nationwide-cohort-study-in-taiwan
#18
Chun-Yuan Lee, I-An Jen, Yu-Ching Lan, Yung-Feng Yen, Pei-Hung Chuang, Marcelo Chen, Yun Lee, Yi-Ming A Chen
BACKGROUND: Although Taiwan has implemented several important interventions for various HIV-at-risk populations to combat the HIV epidemic, little is known regarding AIDS incidence at presentation and during follow-up among the various HIV-at-risk populations in Taiwan. A better understanding of AIDS incidence trends would help improve patient care and optimize public health strategies aimed at further decreasing HIV-related morbidity and mortality. METHODS: Data from Taiwan Centers for Disease Control-operated Notifiable Diseases Surveillance System and Taiwan National Health Insurance Research Database (1998-2012) was divided into five cohort periods (consecutive 3-year groups)...
May 3, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29718921/a-tale-of-swinger-insects-signatures-of-past-sexuality-between-divergent-lineages-of-a-parthenogenetic-weevil-revealed-by-ribosomal-intraindividual-variation
#19
Marcela S Rodriguero, Sonia A Wirth, Josefina S Alberghina, Analía A Lanteri, Viviana A Confalonieri
Naupactus cervinus (Boheman) (Curculionidae, Naupactini) is a parthenogenetic weevil native to the Paranaense Forest which displays high levels of genetic variation. Two divergent clades were identified, one ranging in forest areas (Forest clade), and the other in open vegetation areas (Grassland clade). Both of them have individuals with high levels of heterozygosity in ribosomal sequences. Investigation of intraindividual variation in ITS1 sequences through cloning and posterior sequencing suggested that mating between both groups most likely occurred in the Paranaense Forest after a secondary contact, which led to fixed heterozygotes as a consequence of parthenogenesis...
2018: PloS One
https://www.readbyqxmd.com/read/29718524/advocacy-and-awareness-integrating-lgbtq-health-education-into-the-prelicensure-curriculum
#20
Paula L McNiel, Kathleen M Elertson
BACKGROUND: An identified gap in the curriculum related to lesbian, gay, bisexual, transgender, and queer (LGBTQ) health needs prompted nursing faculty to implement a collaborative educational offering. LGBTQ individuals experience significant health disparities, compared with heterosexual counterparts. Enhancing established LGBTQ population-specific training to highlight health disparities and awareness of special health care needs was piloted with two clinical groups of senior baccalaureate nursing students (N = 16)...
May 1, 2018: Journal of Nursing Education
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