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alcohol withdrawal syndrome

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https://www.readbyqxmd.com/read/27850538/900-alternative-approach-to-alcohol-withdrawal-syndrome
#1
Jennifer Severing, Adam Manko, William Healy, Derek Brown, Manu Kaushal, Christopher Kempe, Jessica Kynyk
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850515/877-correlation-between-mminds-and-ciwa-ar-scoring-tools-in-patients-with-alcohol-withdrawal-syndrome
#2
Audrey Littlefield, Claire Chan, Dawn Cooper, Jason Heavner, Jeanette Kurtz, Margaret Pisani, Mojdeh Heavner
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850144/504-phenobarbital-versus-benzodiazepines-in-the-treatment-of-alcohol-withdrawal-syndrome
#3
Douglas Hsu, John Marshall, George Abdallah, Randy Hollins, Peter Clardy, Michael Donnino, Kenneth Mukamal
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27816567/efficacy-and-safety-of-adjunctive-bitopertin-versus-placebo-in-patients-with-suboptimally-controlled-symptoms-of-schizophrenia-treated-with-antipsychotics-results-from-three-phase-3-randomised-double-blind-parallel-group-placebo-controlled-multicentre-studies
#4
Dragana Bugarski-Kirola, Nakao Iwata, Snjezana Sameljak, Carol Reid, Thomas Blaettler, Laurie Millar, Tiago Reis Marques, George Garibaldi, Shitij Kapur
BACKGROUND: Many patients with schizophrenia require high doses of medication for their ongoing psychotic symptoms. Glutamate theories and findings from studies showing efficacy of sarcosine, an endogenous, non-selective glycine-reuptake inhibitor mediated by GlyT1, offer an alternative approach. We undertook the SearchLyte trial programme to examine the efficacy of bitopertin, a selective GlyT1-mediated glycine-reuptake inhibitor, as an adjunctive treatment to ongoing antipsychotic treatment...
December 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27734823/-ibogaine-structure-influence-on-human-body-clinical-relevance
#5
REVIEW
Zygmunt Zdrojewicz, Bartłomiej Kuszczak, Natalia Olszak
Ibogaine is a natural chemical compound, which belongs to the indole alkaloid family. It can be naturally found within the root bark of african plant Tabernanthe iboga. Ibogaine plays a significant role among tribal cultures. Ibogaine, in small amount, causes reduction of hunger, thirst and exhaustion. In bigger amount, however, it can cause intensive visions. Other effects include reduction or complete disappearance of absitnence symptoms visible in people addicted to the nicotine, alcohol, methamphetamine, cocaine or opioids, what has been scientifically proven after the tests on animals and small groups of people...
July 29, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27733668/evaluation-of-a-symptom-triggered-benzodiazepine-protocol-utilizing-sas-and-ciwa-ar-scoring-for-the-treatment-of-alcohol-withdrawal-syndrome-in-the-critically-ill
#6
Soumitra Sen, Philip Grgurich, Amanda Tulolo, Andrew Smith-Freedman, Yuxiu Lei, Anthony Gray, James Dargin
BACKGROUND: There are limited data on the efficacy of symptom-triggered therapy for alcohol withdrawal syndrome (AWS) in the intensive care unit (ICU). OBJECTIVE: To evaluate the safety and efficacy of a symptom-triggered benzodiazepine protocol utilizing Riker Sedation Agitation Scale (SAS) scoring for the treatment of AWS in the ICU. METHODS: We performed a before-and-after study in a medical ICU. A protocol incorporating SAS scoring and symptom-triggered benzodiazepine dosing was implemented in place of a protocol that utilized the Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar) scale and fixed benzodiazepine dosing...
October 12, 2016: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/27699780/diet-and-headache-part-1
#7
Vincent T Martin, Brinder Vij
BACKGROUND: The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES: To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of elimination diets in the prevention of headache disorders METHODS: This represents part 1 of a narrative review of the role of diet in the prevention of migraine and other headache disorders...
October 2016: Headache
https://www.readbyqxmd.com/read/27586815/alcohol-withdrawal-syndrome-mechanisms-manifestations-and-management
#8
REVIEW
S Jesse, G Bråthen, M Ferrara, M Keindl, E Ben-Menachem, R Tanasescu, E Brodtkorb, M Hillbom, M A Leone, A C Ludolph
The alcohol withdrawal syndrome is a well-known condition occurring after intentional or unintentional abrupt cessation of heavy/constant drinking in patients suffering from alcohol use disorders (AUDs). AUDs are common in neurological departments with patients admitted for coma, epileptic seizures, dementia, polyneuropathy, and gait disturbances. Nonetheless, diagnosis and treatment are often delayed until dramatic symptoms occur. The purpose of this review is to increase the awareness of the early clinical manifestations of AWS and the appropriate identification and management of this important condition in a neurological setting...
January 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27542731/baclofen-to-prevent-agitation-in-alcohol-addicted-patients-in-the-icu-study-protocol-for-a-randomised-controlled-trial
#9
Mickael Vourc'h, Fanny Feuillet, Pierre-Joachim Mahe, Véronique Sebille, Karim Asehnoune
BACKGROUND: Alcohol is the leading psychoactive substance consumed in France, with about 15 million regular consumers. The National institute on Alcohol Abuse and Alcoholism (NIAAA) considers alcohol abuse to be more than 14 units of alcohol a week for men and 7 units for women. The specific complication of alcoholism is the alcohol withdrawal syndrome. Its incidence reaches up to 30 % and its main complications are delirium tremens, restlessness, extended hospital stay, higher morbidity, and psychiatric and cognitive impairment...
August 19, 2016: Trials
https://www.readbyqxmd.com/read/27484692/are-alcohol-anti-relapsing-and-alcohol-withdrawal-drugs-useful-in-cannabinoid-users
#10
Patrycja Kleczkowska, Irena Smaga, Małgorzata Filip, Magdalena Bujalska-Zadrozny
Cannabinoids are still classified as illegal psychoactive drugs despite their broad and increasingly acknowledged therapeutic potential. These substances are most famous for their wide recreational use, particularly among young adults to either alter the state of consciousness, intensify pleasure induced by other psychoactive substances or as an alternative to the previously abused drugs. It is important to emphasize that cannabinoids are often taken together with a variety of medications intended for the treatment of alcohol use disorder (AUD) or alcohol withdrawal syndrome (AWS)...
November 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/27456905/-alcoholism-at-the-end-of-1980-s-and-beginning-of-2010-s
#11
A V Nemtsov, A V Orlov
AIM: To study the 20-years' clinical alteration and alcoholism basing on the changes in its clinical symptoms and course. MATERIAL AND METHODS: The study included 527 alcoholics with formed alcohol withdrawal syndrome: 181 alcoholics were examined in 1988-1990 (Group 1) and 346 alcoholics in 2011-2012 (Group 2). RESULTS AND CONCLUSION: In Group 1, vodka consumption dominated at all stages of alcoholism. Group 2 included 172 alcoholics with the domination of vodka consumption and 174 alcoholics with mixed consumption...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27383853/missed-opportunities-for-health-promotion-intervention-in-the-management-of-alcohol-withdrawal-syndrome
#12
Jessica Johnson, David E Wilson, Bennett P deBoisblanc
OBJECTIVE: We aimed to characterize utilization of evidence-based health promotion practices not included in Alcohol Withdrawal Syndrome (AWS) guidelines, such as vaccinations and counseling services, hypothesizing that missed opportunities for health promotion intervention would abound. METHODS: Retrospective medical record review of 99 patients presenting to a safety-net academic medical center with AWS between August 1, 2012 and March 31, 2013. RESULTS: Thiamine replacement (70%), tobacco cessation counseling (28%), influenza or pneumonia vaccination (25% and 28% respectively), psychiatric counseling (70%), referral to alcohol support group or treatment center(40%), and screening for viral hepatitis and HIV (39% and 44%, respectively) were documented by healthcare providers at lower than optimal frequency...
March 2016: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27303314/trait-impulsivity-and-anhedonia-two-gateways-for-the-development-of-impulse-control-disorders-in-parkinson-s-disease
#13
Jean-Luc Houeto, Robin Magnard, Jeffrey W Dalley, David Belin, Sebastien Carnicella
Apathy and impulsivity are two major comorbid syndromes of Parkinson's disease (PD) that may represent two extremes of a behavioral spectrum modulated by dopamine-dependent processes. PD is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta to which are attributed the cardinal motor symptoms of the disorder. Dopamine replacement therapy (DRT), used widely to treat these motor symptoms, is often associated with deficits in hedonic processing and motivation, including apathy and depression, as well as impulse control disorders (ICDs)...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27212829/central-pontine-myelinolysis-in-a-case-of-alcohol-dependence-syndrome
#14
Kaushik Chatterjee, Austin B Fernandes, Sunil Goyal, Sunitha Shanker
Osmotic Demyelination Syndrome includes Central Pontine Myelinolysis and Extrapontine Myelinolysis. This condition has been described in cases of chronic Alcohol Dependence Syndrome and in rapid correction of hyponatremia. Though we frequently see patients with Alcohol Dependence Syndrome presenting with complicated withdrawal, Central Pontine Myelinolysis remains largely undetected and under-reported in literature. We present here a case of protracted Delirium Tremens where MRI brain revealed Central Pontine Myelinolysis...
July 2015: Industrial Psychiatry Journal
https://www.readbyqxmd.com/read/27207572/the-role-of-barbiturates-for-alcohol-withdrawal-syndrome
#15
REVIEW
Katherine Martin, Andrew Katz
BACKGROUND: Benzodiazepine-resistant cases of alcohol withdrawal syndrome are common, and therefore alternate treatments are needed. OBJECTIVE: Our aim was to conduct a systematic review of published reports on the use of barbiturates for alcohol withdrawal syndrome. METHODS: We performed a systematic literature search of PUBMED for relevant citations that described the use of barbiturates either alone or in conjunction with other pharmacological agents to treat alcohol withdrawal syndrome...
July 2016: Psychosomatics
https://www.readbyqxmd.com/read/27198074/-postictal-psychoses-clinical-and-neurobiological-findings
#16
B de Toffol, K Kanemoto
Psychosis in epilepsy can be categorized in relation to seizures in two main categories: interictal psychosis and postictal psychosis. Postictal psychosis (PIP) is a specific syndrome in relation to seizure activity: a clear temporal relation exists between the psychotic state of sudden onset and a precipitating bout of complex partial or generalized seizures. However, this very specific syndrome is not included as such within the DSM-5, and PIP belongs to the category "Psychotic disorder due to another medical condition"...
May 16, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27196747/management-of-acute-alcohol-withdrawal-syndrome-in-critically-ill-patients
#17
REVIEW
Deepali Dixit, Jeffrey Endicott, Lisa Burry, Liz Ramos, Siu Yan Amy Yeung, Sandeep Devabhakthuni, Claire Chan, Anthony Tobia, Marilyn N Bulloch
Approximately 16-31% of patients in the intensive care unit (ICU) have an alcohol use disorder and are at risk for developing alcohol withdrawal syndrome (AWS). Patients admitted to the ICU with AWS have an increased hospital and ICU length of stay, longer duration of mechanical ventilation, higher costs, and increased mortality compared with those admitted without an alcohol-related disorder. Despite the high prevalence of AWS among ICU patients, no guidelines for the recognition or management of AWS or delirium tremens in the critically ill currently exist, leading to tremendous variability in clinical practice...
July 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27190276/intermittent-hypoxia-training-protects-cerebrovascular-function-in-alzheimer-s-disease
#18
Eugenia B Manukhina, H Fred Downey, Xiangrong Shi, Robert T Mallet
Alzheimer's disease (AD) is a leading cause of death and disability among older adults. Modifiable vascular risk factors for AD (VRF) include obesity, hypertension, type 2 diabetes mellitus, sleep apnea, and metabolic syndrome. Here, interactions between cerebrovascular function and development of AD are reviewed, as are interventions to improve cerebral blood flow and reduce VRF. Atherosclerosis and small vessel cerebral disease impair metabolic regulation of cerebral blood flow and, along with microvascular rarefaction and altered trans-capillary exchange, create conditions favoring AD development...
June 2016: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27180426/serum-antioxidant-parameters-in-patients-poisoned-by-different-xenobiotics
#19
COMPARATIVE STUDY
Piotr Hydzik, Mirosław Krośniak, Renata Francik, Ewa Gomółka, Ebru Derici Ebru, Paweł Zagrodzki
There is a great diversity of the acute drugs overdose cases in clinical toxicology. Clinical situation is complicated by the coexistence of factors predisposing to the development of adverse drug reactions (chronic use of drugs, polypharmacy, alcohol or drugs dependence, nutritional disorders) and by the presence of chronic organ damage, especially the liver and the kidney. The aim of this study was to evaluate whether there are sensitive plasma markers belonging to the antioxidant system in patients exposed to various xenobiotics...
March 2016: Acta Poloniae Pharmaceutica
https://www.readbyqxmd.com/read/27168398/treatment-of-alcohol-withdrawal-syndrome-with-and-without-dexmedetomidine
#20
Muna Beg, Sara Fisher, Dana Siu, Sudhir Rajan, Lawrence Troxell, Vincent X Liu
CONTEXT: Studies suggest that dexmedetomidine-an intravenous central-acting α2-adrenergic agonist that effectively reduces anxiety among critically ill patients-is being used in patients with severe alcohol withdrawal. However, evidence supporting its use is limited, and it is not approved for this indication. OBJECTIVE: To assess the effect of dexmedetomidine on severe alcohol withdrawal symptoms and to compare its use with benzodiazepines alone. DESIGN: A retrospective, cohort study of 77 patients admitted to the adult medical intensive care unit with severe alcohol withdrawal between January 1, 2009, and October 31, 2013...
2016: Permanente Journal
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