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endoscopic mucosal resection

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https://www.readbyqxmd.com/read/28924587/colorectal-endoscopic-submucosal-dissection-predictors-and-neoplasm-related-gradients-of-difficulty
#1
Federico Iacopini, Yutaka Saito, Antonino Bella, Takuji Gotoda, Patrizia Rigato, Walter Elisei, Fabrizio Montagnese, Giampaolo Iacopini, Guido Costamagna
BACKGROUND AND STUDY AIM:  The role of colorectal endoscopic submucosal dissection (ESD) is standardized in Japan and East Asia, but technical difficulties hinder its diffusion. The aim was to identify predictors of difficulty for each neoplasm type. METHODS:  A competent operator performed all procedures. ESD difficulty was defined as: en bloc with a slow speed (< 0.07 cm (2) /min; 30 × 30 mm neoplasm in > 90 min), conversion to endoscopic mucosal resection, or resection abandonment...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28917905/characterization-of-a-water-soluble-chitosan-derivative-and-its-potential-for-submucosal-injection-in-endoscopic-techniques
#2
Hidemi Hattori, Hironori Tsujimoto, Kazuo Hase, Masayuki Ishihara
To examine the potential of chitosan-based agents for submucosal injection in endoscopic techniques, a chitosan derivative was prepared with lactose moieties linked to the amino groups of its glucosamine units (CH-LA). After dissolving CH-LA in neutral pH solutions, including physiological saline (CH-LA-S), its response to different concentrations of anionic glycosaminoglycans and proteins in the surrounding environment was examined. The CH-LA-S form changed in the presence of sulfated glycosaminoglycans (heparin, chondroitin sulfate, and mucin) and protein (fibrinogen)...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28904301/a-case-of-gastric-lipoma-resected-by-endoscopic-submucosa-dissection-with-difficulty-in-preoperative-diagnosis
#3
Mizue Ichinose, Takuto Hikichi, Yukiko Kanno, Naohiko Gunji, Masashi Fujita, Masahito Kuroda, Kumiko Terashima, Yoshinori Sato, Satoshi Kawana, Yuko Hashimoto, Hiromasa Ohira, Masayuki Miyata
A 66-year-old man was referred to our hospital with an increasing subepithelial lesion in the gastric antrum. Using esophagogastroduodenoscopy, a tumor with a steep, 20-mm-high rise protruding in the lumen was observed. The mucosal surface of the tumor was reddish, with ulcers forming at the base. Moreover, the tumor was mobile and soft. A biopsy specimen was taken from the ulcer, but tumor tissue was not collected from the submucosa. Endoscopic ultrasonography (EUS) showed a high echoic mass in the submucosa...
September 14, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28900992/-clinicopathologic-characteristics-and-prognosis-of-rectal-neuroendocrine-neoplasms
#4
Tao Liu, Ping Liu, Tao Wu, Yisheng Pan, Guowei Chen, Pengyuan Wang, Yong Jiang, Yingchao Wu, Xin Wang
OBJECTIVE: To study the clinicopathologic characteristics and prognosis of rectal neuroendocrine neoplasms (NENs). METHODS: From January 2000 to May 2017, 84 patients were diagnosed as NENs by pathology and underwent surgical treatment in Peking University First Hospital. Their clinicopathological characteristics, surgial options and prognosis were analyzed retrospectively. RESULT: Among these 84 cases, 67 cases were NET G1, 6 cases were NET G2, 10 cases were NEC G3 and 1 case was MANEC G3...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28900991/-transanal-endoscopic-microsurgery-for-treatment-of-rectal-neuroendocrine-tumors
#5
Qianqian Shao, Guole Lin, Huizhong Qiu
OBJECTIVE: To assess the efficacy of full-thickness excision using transanal endoscopic microsurgery (TEM) in the treatment of rectal neuroendocrine tumors (NET). METHODS: Clinicopathological and follow-up data of 90 rectal NET patients who underwent TEM between December 2006 and December 2016 at our department were retrospectively analyzed. TEM was performed as primary excision in 66 patients and as the second complete surgery because of suspected positive margin of samples after colonoscopic polypectomy in 24 patients...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28899721/clinical-challenges-and-images-in-gastroenterology-endoscopic-resection-of-esophageal-mucosal-bridge
#6
Abhilash Perisetti, Debdeep Banerjee, Benjamin Tharian
No abstract text is available yet for this article.
September 9, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28898922/cold-versus-hot-endoscopic-mucosal-resection-for-nonpedunculated-colorectal-polyps-sized-6-10-mm-a-randomized-trial
#7
Vasilios Papastergiou, Konstantina D Paraskeva, Maria Fragaki, Ioannis Dimas, Emmanouil Vardas, Angeliki Theodoropoulou, Nicoletta Mathou, Athanasios Giannakopoulos, Konstantinos Karmiris, Afroditi Mpitouli, Dimitra Apessou, Linda Giannikaki, John A Karagiannis, Grigorios Chlouverakis, Gregorios A Paspatis
Background and study aims Cold snare polypectomy is an established method for the resection of small colorectal polyps; however, significant incomplete resection rates still leave room for improvement. We aimed to assess the efficacy of cold snare endoscopic mucosal resection (CS-EMR), compared with hot snare endoscopic mucosal resection (HS-EMR), for nonpedunculated polyps sized 6 - 10 mm. Patients and methods This study was a dual-center, randomized, noninferiority trial. Consecutive adult patients with at least one nonpedunculated polyp sized 6 - 10 mm were enrolled...
September 12, 2017: Endoscopy
https://www.readbyqxmd.com/read/28894617/idiopathic-myointimal-hyperplasia-of-mesenteric-veins-of-the-ileum-and-colon-in-a-patient-with-crohn-s-disease-a-case-report-and-brief-review-of-the-literature
#8
Sharon J Song, Stuti G Shroff
Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare disease characterized by intimal smooth muscle proliferation, leading to the thickening of small to medium-sized mesenteric veins. This vascular disease mimics inflammatory bowel disease (IBD) clinically and endoscopically, while showing ischemic mucosal changes without the classic features of IBD on biopsy. Given the mixed picture, this entity is frequently misdiagnosed. Surgical resection of the diseased bowel segment reveals the true etiology of the pathology and is curative...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28893560/endoscopic-mucosal-resection-is-superior-to-rectal-suction-biopsy-for-analysis-of-enteric-ganglia-in-constipation-and-dysmotility
#9
Kenneth Barshop, Field F Willingham, William R Brugge, Lawrence R Zukerberg, Braden Kuo
BACKGROUND AND AIMS: Patients with chronic constipation or motility disorders may be referred for rectal suction biopsy (RSB) to rule out Hirschsprung's disease (HD). RSB may not be successful beyond infancy due to the increased thickness of rectal mucosa. Endoscopic mucosal resection (EMR) could improve the diagnostic yield for HD when compared with traditional RSB because of the larger and deeper samples acquired for analysis. METHODS: In this prospective, single-center study, patients referred for RSB were offered enrollment for concurrent EMR...
September 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28884225/safety-of-endoscopic-mucosal-resection-emr-of-large-non-pedunculated-colorectal-adenomas-in-the-elderly
#10
K Bronsgeest, J F Huisman, A Langers, J J Boonstra, B E Schenk, W H de Vos Tot Nederveen Cappel, H F A Vasen, J C H Hardwick
BACKGROUND: Endoscopic mucosal resection (EMR) has been proven to be safe and effective for the treatment of colorectal adenomas. However, data are limited on the safety of this technique for large polyps and in elderly patients. Aims of our study were to examine the bleeding and perforation rates in patients with large non-pedunculated adenomas (≥20mm) and to evaluate the influence of size (≥40mm) and age (≥75 years) on the complication rates. METHODS: In this multicenter retrospective study, patients who underwent EMR of non-pedunculated adenomas ≥20mm between January 2012 and March 2016 were included...
September 8, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28881059/pancreas-preserving-duodenectomy-after-living-donor-liver-transplantation-for-invasive-cytomegalovirus-disease
#11
Rodrigo Vincenzi, Eduardo A Fonseca, Paulo Chapchap, Marcel C C Machado, Karina M O Roda, Helry L Candido, Marcel R Benavides, Marco A D'Assuncao, Rogerio C Afonso, Plinio Turine, Fernando P Marson, João Seda Neto
CMV infection plays an important role in the postoperative course following solid organ transplantation. We present the case of an 11-year-old male patient who underwent LDLT due to severe hepatopulmonary syndrome and biliary cirrhosis. Four weeks after LDLT, he developed persistent GI bleeding and was subjected to repeated endoscopic treatment and radiological arterial embolization to stop the bleeding from duodenal ulcers. Diagnostic workup was negative for CMV disease. Because the bleeding persisted, surgical treatment was indicated, and a pancreas-preserving duodenectomy was performed...
September 7, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28877814/limited-resection-of-the-duodenum-for-nonampullary-duodenal-tumors-with-review-of-the-literature
#12
REVIEW
Daisuke Hashimoto, Kota Arima, Akira Chikamoto, Katsunobu Taki, Risa Inoue, Takayoshi Kaida, Takaaki Higashi, Katsunori Imai, Toru Beppu, Hideo Baba
The surgical management of duodenal pathology is challenging because of its retroperitoneal position and shared blood supply with the pancreas. We present three types of limited resection of the duodenum for the removal of superficial or small nonampullary duodenal (NADL) lesions, and also a review of the English literature regarding management, such as endoscopic resection and limited duodenal resection. Ten cases underwent limited resections of the duodenum for superficial or small NADL lesions from 2011 to 2015...
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28874418/therapeutic-endoscopy-related-gi-bleeding-and-thromboembolic-events-in-patients-using-warfarin-or-direct-oral-anticoagulants-results-from-a-large-nationwide-database-analysis
#13
Naoyoshi Nagata, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Kazuhiro Watanabe, Junichi Akiyama, Naomi Uemura, Ryota Niikura
OBJECTIVE: To compare the risks of postendoscopy outcomes associated with warfarin with direct oral anticoagulants (DOACs), taking into account heparin bridging and various types of endoscopic procedures. DESIGN: Using the Japanese Diagnosis Procedure Combination database, we identified 16 977 patients who underwent 13 types of high-risk endoscopic procedures and took preoperative warfarin or DOACs from 2014 to 2015. One-to-one propensity score matching was performed to compare postendoscopy GI bleeding and thromboembolism between the warfarin and DOAC groups...
September 5, 2017: Gut
https://www.readbyqxmd.com/read/28874041/the-advantage-of-an-endoscopic-submucosal-tunneling-technique-for-rectal-carcinoid-tumors
#14
Hideki Kobara, Hirohito Mori, Li Chei, Shintaro Fujihara, Noriko Nishiyama, Tsutomu Masaki
Endoscopic treatment can be a curative option for small carcinoid tumors with an extremely low risk of metastasis. Since most carcinoid tumors are characterized by a specific growth pattern in the submucosal (SM) layer, specialized endoscopic techniques for deeper resection to achieve clear vertical margins are needed. The endoscopic submucosal dissection (ESD) method in the SM space is superior to conventional endoscopic mucosal resection. However, the standard ESD technique sometimes fails to provide complete deep SM dissection due to insufficient SM lifting...
September 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28871579/a-case-of-pedunculated-esophageal-leiomyoma-successfully-treated-by-endoscopic-mucosal-resection
#15
Shingo Tsuda, Masashi Matsushima, Takayoshi Suzuki, Aya Kawanishi, Joaquim Carreras, Jun Nakamura, Yoko Tsukune, Tetsufumi Uchida, Jun Koike, Muneki Igarashi, Tetsuya Mine, Yutaka Imai
Leiomyoma is one of the most commonly observed esophageal submucosal tumors, often appearing as a smooth-surfaced and semicircular protruded lesion. It sometimes grows toward the esophageal lumen and may be pedunculated in rare cases. We encountered a case of a pedunculated esophageal submucosal tumor diagnosed before treatment as a leiomyoma originating in the muscularis mucosae of a 68-year-old man. As the tumor arose in the muscularis mucosae, it could be safely resected via an endoscopic procedure. Only one case of pedunculated leiomyoma has been reported to date, and we herein report the second case, which was successfully treated by a minimally invasive endoscopic technique...
September 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28870046/-the-chinese-consensus-for-screening-diagnosis-and-management-of-barrett-s-esophagus-and-early-adenocarcinoma-2017-wanning
#16
(no author information available yet)
Patients with Barrett's esophagus (BE)/columnar lined esophagus (CLE) and adenocarcinoma are increasing, in whom 0.61% BE/CLE would develop to adenocarcinoma. The prognosis of esophageal cancer is related to the tumor stage at diagnosis. To standardize the screening, diagnosis and therapy of BE and adenocarcinoma in China, 31 digestive diseases and digestive endoscopy experts and digestive histologists drafted the consensus on the basis of clinical experience and references. The consensus defined BE as a complication of gastroesophageal reflux disease...
September 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28859952/predictors-of-post-colonoscopy-emergency-department-use
#17
Laurie B Grossberg, Alina Vodonos, Konstantinos Papamichael, Victor Novack, Mandeep Sawhney, Daniel A Leffler
BACKGROUND AND AIMS: Unplanned hospital visits within 7 days of colonoscopy was recently proposed as a quality measure. It is unknown if patient, procedure, or endoscopist characteristics predict post-colonoscopy emergency department (ED) visits. Our aim was to determine the incidence and relatedness of ED visits within 7 days of colonoscopy, and to identify predictors of post-colonoscopy ED use. METHODS: In this retrospective, single-center, cohort study, we evaluated outpatient colonoscopies performed at a tertiary academic medical center or affiliated facility between January 2008 and September 2013...
August 28, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28859713/draf-iii-frontal-sinus-surgery-how-i-do-it
#18
A Simon Carney
BACKGROUND: The Draf III approach to the frontal sinus can be used during revision endoscopic sinus surgery for chronic rhinosinusitis and to provide access for tumor resection, mucoceles, and repair of cerebrospinal fluid leaks. OBJECTIVE: To describe a simple and safe way to perform a Draf III approach by using the "outside-in" approach. METHODS: By using a 0° endoscope and a single 15°, 5-mm, coarse diamond burr, the main steps of the procedure are the following: (1) elevation of the mucosal flaps and creation of the septal window, (2) drilling out the frontal beak, (3) creation of neo-ostium and removal of the interfrontal septum, (4) joining the neo-ostium with the frontal recesses, (5) smoothing off the cavity and lowering of the "frontal T," and (6) use of mucosal flaps and grafts to cover exposed bone...
September 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28852321/systematic-review-of-giant-gastric-lipomas-reported-since-1980-and-report-of-two-new-cases-in-a-review-of-117110-esophagogastroduodenoscopies
#19
Mitchell S Cappell, Charlton E Stevens, Mitual Amin
AIM: To systematically review the syndrome of giant gastric lipomas, report 2 new illustrative cases. METHODS: Literature systematically reviewed using PubMed for publications since 1980 with following medical subject heading/keywords: ("giant lipoma") AND ("gastric") OR [("lipoma") and ("gastric") and ("bleeding")]. Two authors independently reviewed literature, and decided by consensus which articles to incorporate. Computerized review of pathology/endoscopy records at William Beaumont Hospitals, Royal Oak and Troy, Michigan, January 2005-December 2015, revealed 2 giant gastric lipomas among 117110 consecutive esophagogastroduodenoscopies (EGDs), which were thoroughly reviewed, including re-review of original endoscopic photographs, radiologic images, and pathologic slides...
August 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28845102/endoscopic-electrocautery-incision-therapy-for-benign-lower-gastrointestinal-tract-anastomotic-strictures
#20
REVIEW
Deepanshu Jain, Naemat Sandhu, Shashideep Singhal
Benign anastomotic strictures can occur in up to 22% of patients who undergo colonic or rectal resection. Traditionally, surgery was the preferred method of treatment, but, over time, endoscopic techniques, such as balloon dilation, have become the preferred modality. However, a high stricture recurrence rate of up to 18-20% and the increased risk of perforation due to uncontrolled stretching are its major drawbacks. Endoscopic electrocautery incision (EECI) allows for controlled mucosal incision in predetermined locations of stricture...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
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