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endoscopic mucosal resection

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https://www.readbyqxmd.com/read/28342132/endoscopic-mucosal-resection-versus-esophagectomy-for-intramucosal-adenocarcinoma-in-the-setting-of-barrett-s-esophagus
#1
Chao Li, Denise Tami Yamashita, Jeffrey David Hawel, Drew Bethune, Harry Henteleff, James Ellsmere
BACKGROUND: Esophagectomy has been the standard of care for patients with intramucosal adenocarcinoma (IMC) in the setting of Barrett's esophagus. It is, however, associated with significant post-operative morbidity and mortality. Endoscopic mucosal resection (EMR) offers a minimally invasive approach with lesser morbidity. This study investigates the transition from esophagectomy to EMR for IMC with respect to eradication rates, post-operative morbidity, and long-term survival. METHODS: Patients diagnosed with IMC from 2005 to 2013 were identified retrospectively...
March 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28342125/underwater-endoscopic-mucosal-resection-is-associated-with-fewer-recurrences-and-earlier-curative-resections-compared-to-conventional-endoscopic-mucosal-resection-for-large-colorectal-polyps
#2
Robert J Schenck, Darius A Jahann, James T Patrie, Edward B Stelow, Dawn G Cox, Dushant S Uppal, Bryan G Sauer, Vanessa M Shami, Daniel S Strand, Andrew Y Wang
BACKGROUND: Studies comparing the efficacy and safety of conventional saline-assisted piecemeal endoscopic mucosal resection (EMR) to underwater EMR (UEMR) without submucosal lifting of colorectal polyps are lacking. The objective of this study was to compare the efficacy and safety of EMR to UEMR of large colorectal polyps. METHODS: Two hundred eighty-nine colorectal polyps were removed by a single endoscopist from 7/2007 to 2/2015 using EMR or UEMR. 135 polyps (EMR: 62, UEMR: 73) that measured ≥15 mm and had not undergone prior attempted polypectomy were evaluated for rates of complete macroscopic resection and adverse events...
March 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28341823/a-case-with-serrated-polyposis-syndrome-controlled-by-multiple-applications-of-endoscopic-mucosal-resection-and-endoscopic-submucosal-dissection
#3
Daisuke Suzuki, Satohiro Matsumoto, Hirosato Mashima
BACKGROUND Serrated polyposis syndrome (SPS) is characterized by numerous hyperplastic polyps and sessile serrated adenoma/polyp (SSA/P) in the large intestine. SSA/P is known to transform into malignant lesions through the serrated pathway instead of the adenoma-carcinoma sequence. Early diagnosis with lower gastrointestinal endoscopy and early treatment are now considered to be essential. CASE REPORT We had an experience with a case of SPS to which endoscopic treatment was applied in multiple sessions. Endoscopic treatment was performed for 16 lesions in total, and the pathological findings were SSA/P for 15 and adenoma for the other lesion...
March 25, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28338468/endoscopic-mucosal-resection-for-high-grade-dysplasia-and-intramucosal-carcinoma-a-canadian-experience
#4
Denise Tami Yamashita, Chao Li, Drew Bethune, Harry Henteleff, James Ellsmere
BACKGROUND: Endoscopic mucosal resection (EMR) is increasingly being used as a first-line treatment for Barrett esophagus (BE) with high-grade dysplasia (HGD) and intramucosal adenocarcinoma (IMC). We reviewed our experience with endoscopic treatment of BE with HGD and IMC at our institution with respect to eradication rates, complications and long-term recurrence. METHODS: We performed a single-centre retrospective review of all patients referred between October 2010 and August 2014 for EMR with dysplastic BE or IMC...
April 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28337479/technical-feasibility-of-line-assisted-complete-closure-technique-for-large-mucosal-defects-after-colorectal-endoscopic-submucosal-dissection
#5
Minoru Kato, Yoji Takeuchi, Yasushi Yamasaki, Masamichi Arao, Sho Suzuki, Taro Iwatsubo, Kenta Hamada, Yusuke Tonai, Satoki Shichijo, Noriko Matsuura, Hiroko Nakahira, Takashi Kanesaka, Tomofumi Akasaka, Noboru Hanaoka, Koji Higashino, Noriya Uedo, Ryu Ishihara, Hiroyasu Iishi
Background and study aims Complete closure of large mucosal defects after colorectal endoscopic submucosal dissection (C-ESD) is considered impossible in most cases because of the limited width of the open clip. We therefore invented a simple closure technique using clip-and-line, named "line-assisted complete closure (LACC)", and assessed its technical feasibility. Patients and methods Between January and February 2016, we performed LACC in 11 patients after C-ESD and included them in this retrospective feasibility study...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28337366/natural-history-of-early-gastric-cancer-a-case-report-and-literature-review
#6
Tomohiro Iwai, Masao Yoshida, Hiroyuki Ono, Naomi Kakushima, Kohei Takizawa, Masaki Tanaka, Noboru Kawata, Sayo Ito, Kenichiro Imai, Kinichi Hotta, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi
Early detection and treatment decrease the mortality rate associated with gastric cancer (GC). However, the natural history of GC remains unclear. An 85-year-old woman was referred to our hospital for evaluation of a gastric tumor. Esophagogastroduodenoscopy identified a 6 mm, flat-elevated lesion at the lesser curvature of the antrum. A biopsy specimen showed a well-differentiated tubular adenocarcinoma. The depth of the lesion was estimated to be intramucosal. Although the lesion met the indications for endoscopic resection, periodic endoscopic follow-up was performed due to the patient's advanced age and comorbidities...
March 2017: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/28329876/underwater-endoscopic-mucosal-resection-for-complete-r0-removal-of-a-residual-adenoma-at-a-perforated-scar-in-a-patient-with-colostomy
#7
Kazuya Hosotani, Kenichiro Imai, Kinichi Hotta, Sayo Ito, Hiroyuki Ono
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28321377/single-layer-repair-of-large-anterior-skull-base-defects-without-vascularized-mucosal-flap
#8
Frederick Yoo, Marilene B Wang, Marvin Bergsneider, Jeffrey D Suh
Objectives Bilateral anterior skull base (ASB) defects following endoscopic endonasal tumor resection are most commonly repaired utilizing multilayered reconstruction with a vascularized mucosal flap. Single-layer closure of large ASB defects has been described in the literature but this technique has yet to gain a widespread use. We report our experience with a series of patients who underwent reconstruction of large ASB defects using a single-layer intradural graft, without nasoseptal flaps. We also compared the use of acellular dermal matrix (AlloDerm, LifeCell, Branchburg, New Jersey, United States) or collagen matrix xenograft (Duramatrix, Stryker, Kalamazoo, Michigan, United States) as the graft biomaterial...
April 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28317588/applicability-of-endoscopic-submucosal-dissection-for-undifferentiated-early-gastric-cancer-mixed-histology-of-poorly-differentiated-adenocarcinoma-and-signet-ring-cell-carcinoma-is-a-worse-predictive-factor-of-nodal-metastasis
#9
In Seob Lee, Sol Lee, Young Soo Park, Chung Sik Gong, Jeong Hwan Yook, Byung Sik Kim
BACKGROUND: Endoscopic submucosal dissection (ESD) is not considered an appropriate treatment for undifferentiated early gastric cancer (UEGC) due to the higher risk of nodal metastases. We aimed to investigate predictive factors for nodal metastases in UEGCs, determine whether the tumor histology is an independent factor for it, and explore whether ESD is applicable for UEGC. METHODS: We reviewed the medical records of 1837 patients who underwent curative gastrectomy for poorly differentiated adenocarcinoma, signet ring cell carcinoma, and a mixed type of both tumors between 2008 and 2012...
March 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28316766/colonic-laterally-spreading-tumor-diagnosed-as-an-early-cancer-and-treated-with-endoscopic-mucosal-resection-a-case-report-and-review-of-literature
#10
Mohamad Abdelaziz, Motaz Sayed
Laterally spreading tumors (LSTs) are generally defined as superficial lesions ≥10 mm in diameter that typically extend laterally rather than vertically along the colonic wall. Such lesions are now increasingly reported because of increased awareness and the introduction of chromo and magnifying colonoscopy. Although the clinicopathological characteristics and the efficacy of endoscopic management of LSTs have been defined in Japanese cohorts, reports from the Middle East are lacking where surgical resection is the mainstay of treatment...
January 2017: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28316760/handling-and-pathology-reporting-of-gastrointestinal-endoscopic-mucosal-resection
#11
REVIEW
Bita Geramizadeh, David A Owen
Endoscopic mucosal resection (EMR) is a non-invasive alternative to surgery that is now frequently used for resection of early lesions in both upper and lower parts of the gastrointestinal (GI) tract. One of the main advantages of these techniques is providing tissue for histopathological examination. Pathological examination of endoscopically resected specimens of GI tract is a crucial component of these procedures and is useful for prediction of both the risk of metastasis and lymph node involvement. As the first step, it is very important for the pathologist to handle the EMR gross specimen in the correct way: it should be oriented, and then the margins should be labeled and inked accurately before fixation...
January 2017: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28316622/risk-factors-for-additional-surgery-after-iatrogenic-perforations-due-to-endoscopic-submucosal-dissection
#12
Gi Jun Kim, Sung Min Park, Joon Sung Kim, Jeong Seon Ji, Byung Wook Kim, Hwang Choi
Objectives. Endoscopic resection (ER) is commonly performed to treat gastric epithelial neoplasms and subepithelial tumors. The aim of this study was to predict the risk factors for surgery after ER-induced perforation. Methods. We retrospectively reviewed the data on patients who received gastric endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) between January 2010 and March 2015. Patients who were confirmed to have perforation were classified into surgery and nonsurgery groups...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28301879/laparoscopic-transgastric-circumferential-stapler-assisted-vs-endoscopic-esophageal-mucosectomy-in-a-porcine-model
#13
Daniel C Steinemann, Andreas Zerz, Philip C Müller, Peter Sauer, Anja Schaible, Felix Lasitschka, Anne-Catherine Schwarz, Beat P Müller-Stich, Georg R Linke
Background and study aims Extensive endoscopic mucosal resection (EMR) for Barrett's esophagus (BE) may lead to stenosis. Laparoscopic, transgastric, stapler-assisted mucosectomy (SAM) with the retrieval of a circumferential specimen is proposed. Methods SAM was evaluated in two phases. The feasibility of SAM and the quality of specimens were assessed in eight animals. The mucosal healing was evaluated in a 6-week survival experiment comparing SAM (n = 6) with EMR (n = 6). The ratio of the esophageal lumen width (REL) at the resection level measured on fluoroscopy at 6 weeks divided by the width immediately after resection was compared...
March 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/28288842/thermo-sensitive-isopentane-aerification-for-mucosal-lift-during-endoscopic-resection-in-animal-models-with-video
#14
Wenjie Liu, Min Wang, Lili Zhao, Min Wang, Xiang Wang, Zhining Fan, Li Liu
BACKGROUND AND AIMS: Mucosal lift is critical for successful endoscopic treatment. Normal saline solution (NS) is widely used as the submucosal filler, but its short persistency restricts clinical endoscopic submucosal dissection (ESD) procedure. In this study, thermo-sensitive isopentane was introduced for submucosal injection. With a 27.8°C boiling point, liquid isopentane could be easily applied, whereas gasification inflation could provide great support for submucosal lifting at body temperature...
March 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28288471/early-stage-gastric-cancer-can-be-found-in-improved-atrophic-mucosa-over-time-from-successful-helicobacter-pylori-eradication
#15
Atsushi Majima, Osamu Handa, Yuji Naito, Osamu Dohi, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Yoshito Itoh
BACKGROUND/AIMS: Early-stage gastric cancer (EGC) is detected even after successful Helicobacter pylori eradication. This study is aimed at clarifying the clinicopathological characteristics of EGC detected after successful H. pylori eradication. METHODS: This retrospective study analyzed 57 cases of EGC detected after successful H. pylori eradication and resected endoscopically at Kyoto Prefectural University of Medicine, between January 2009 and June 2014. Clinicopathological findings of 57 cases (H...
March 14, 2017: Digestion
https://www.readbyqxmd.com/read/28286800/solitary-fibrous-tumor-of-the-stomach
#16
Faisal Inayat, Qulsoom Hussain, Khurram Shafique, Abu Hurairah, Evan B Grossman
Solitary fibrous tumor is a rare mesenchymal neoplasm that usually originates from the pleura, but has been reported in other extrapleural locations. We report a rare case of a solitary fibrous tumor of the stomach, which was successfully treated with endoscopic mucosal resection.
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28281119/hybrid-endoscopic-mucosal-resection-and-full-thickness-resection-a-new-approach-for-resection-of-large-non-lifting-colorectal-adenomas-with-video
#17
Benjamin Meier, Karel Caca, Arthur Schmidt
BACKGROUND: Clip-assisted endoscopic full-thickness resection (EFTR) with an over-the-scope device has been recently described to be feasible and effective for the resection of non-lifting adenomas in the lower gastrointestinal tract. However, tumor size is the major limitation of that technique. We describe a hybrid technique using endoscopic mucosal resection (EMR) in ten patients with large non-lifting colorectal adenomas to reduce tumor size and facilitate clip-assisted EFTR. METHODS: Data of ten consecutive patients (median age 72...
March 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28279463/endoscopic-management-of-early-esophagogastric-cancer
#18
REVIEW
Qurat-Ul-Ain Rizvi, Arrhchanah Balachandran, Doreen Koay, Prateek Sharma, Rajvinder Singh
Esophagogastric cancer accounts for the second most common cause of cancer-related mortality worldwide. Significant efforts have been made to detect these malignancies at an earlier stage through the implementation of screening programs in high-risk individuals using advanced diagnostic techniques. Endoscopic management techniques, such as endoscopic mucosal resection and endoscopic submucosal dissection, have consistently demonstrated excellent outcomes in the management of these lesions. These techniques are associated with a lower risk of morbidity and mortality when compared with traditional surgical management...
April 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28275832/endoscopic-treatment-of-high-grade-dysplasia-and-early-esophageal-cancer
#19
Francisco Schlottmann, Marco G Patti, Nicholas J Shaheen
BACKGROUND: The emergence of novel endoscopic modalities has challenged the role of surgery for patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD) or early esophageal adenocarcinoma. AIM: The aim of this study was to review the available evidence of the endoscopic treatment of HGD and early esopahgeal adenocarcinoma. RESULTS: For most patients with BE and HGD, endoscopic ablative therapy is the preferred treatment strategy...
March 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28274828/wide-field-endoscopic-mucosal-resection-in-the-small-bowel-management-of-a-rare-cause-of-jejunal-intussusception-by-double-balloon-enteroscopy
#20
Nikolaos Koukias, Erasmia Vlachou, Peter Wylie, Edward J Despott
No abstract text is available yet for this article.
February 12, 2017: Digestive and Liver Disease
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