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endoscopic mucosal resection

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https://www.readbyqxmd.com/read/29142518/local-recurrence-and-subsequent-endoscopic-treatment-after-endoscopic-piecemeal-mucosal-resection-with-or-without-precutting-in-the-colorectum
#1
Myeongsook Seo, Eun Mi Song, Gwang Un Kim, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Byong Duk Ye, Seung-Jae Myung, Suk-Kyun Yang, Jeong-Sik Byeon
Background/Aims: Precutting before endoscopic piecemeal mucosal resection (EPMR) may increase colorectal polyp resection effectiveness. We aimed to identify risk factors for recurrence after conventional EPMR (CEPMR) and precut EPMR (PEPMR) and investigated endoscopic treatment outcomes for recurrent cases. Methods: The medical records of patients with colorectal polyps treated by EPMR were analyzed. Patients without follow-up surveillance colonoscopies were excluded...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29136630/one-to-one-correspondence-locations-of-resected-polyps-after-endoscopic-resection-using-catcher-tagged-method-a-randomized-prospective-study
#2
Hirohito Mori, Hideki Kobara, Nobuya Kobayashi, Noriko Nishiyama, Seiki Kobayashi, Takaharu Yagi, Tsutomu Masaki
BACKGROUND/AIMS: Multiple colorectal polyps with a diameter in the range of 10-19 mm are unable to be retrieved through a 3-mm endoscopic channel by the aspiration method. This study aims to assess the usefulness of Catcher Tag retrieval, which not only allows the accurate identification of the resected location but also enables the easiest retrieval in a short time without any special device. METHODS: One hundred thirty five patients (483 polyps) were diagnosed with colorectal neoplasm, and 64 patients (225 polyps) were enrolled and randomly allocated into the Net forceps group (NET) and the Catcher Tagged group (TAG)...
November 14, 2017: Digestion
https://www.readbyqxmd.com/read/29133196/cold-endoscopic-mucosal-resection-of-large-sessile-serrated-polyps-at-colonoscopy-with-video
#3
Nicholas J Tutticci, David G Hewett
BACKGROUND AND AIMS: The optimal technique for the resection of sessile serrated polyps (SSPs) is unknown, with established limitations and risks with conventional polypectomy. Although cold snare polypectomy is safe, the efficacy of piecemeal resection for large lesions is untested. In this study, we evaluate the safety and efficacy of cold endoscopic mucosal resection (EMR) for large SSPs. METHODS: Patients presenting for elective colonoscopy at an academic endoscopy center with 1 or more SSPs ≥10mm in size were enrolled, excluding those on anticoagulants or antiplatelets other than aspirin...
November 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29129090/screening-and-prevention-strategies-and-endoscopic-management-of-early-esophageal-cancer
#4
James A Kim, Pari M Shah
Esophageal cancer is the 8th most common cancer worldwide and the 6th most common cause of cancer-related death. Its two main subtypes, esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC), have varying incidences globally, but recent decades have seen a demonstrated rise of EAC in Western countries whereas ESCC remains highly prevalent in Eastern Africa, Central Asia, and China. Screening interventions have focused on using endoscopy to identify Barrett's esophagus (BE) as a precursor to EAC, and squamous cell dysplasia prior to onset of ESCC...
October 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/29124126/safe-management-of-laparoscopic-endoscopic-cooperative-surgery-for-superficial-non-ampullary-duodenal-epithelial-tumors
#5
Yasunori Otowa, Shingo Kanaji, Yoshinori Morita, Satoshi Suzuki, Masashi Yamamoto, Yoshiko Matsuda, Takeru Matsuda, Taro Oshikiri, Tetsu Nakamura, Fumiaki Kawara, Shinwa Tanaka, Tsukasa Ishida, Takashi Toyonaga, Takeshi Azuma, Yoshihiro Kakeji
Background and study aims  Endoscopic submucosal dissection (ESD) for duodenal tumors results in a high delayed perforation rate due to the thinness of the duodenal wall. In most cases with perforation after duodenal ESD, additional surgery is needed due to severe peritonitis. A newly developed procedure, laparoscopic endoscopic cooperative surgery for duodenal tumors (D-LECS), may help to avoid perforation after ESD. In our institution, patients with superficial non-ampullary duodenal epithelial tumors (SNADET) smaller than 50 mm which could not have en-bloc resection by endoscopic mucosal resection were treated with D-LECS...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29118553/endoscopic-management-of-colorectal-adenomas
#6
REVIEW
Benjamin Meier, Karel Caca, Andreas Fischer, Arthur Schmidt
Colorectal adenomas are well known precursors of invasive adenocarcinoma. Colonoscopy is the gold standard for adenoma detection. Colonoscopy is far more than a diagnostic tool, as it allows effective treatment of colorectal adenomas. Endoscopic resection of colorectal adenomas has been shown to reduce the incidence and mortality of colorectal cancer. Difficult resection techniques are available, such as endoscopic mucosal resection, endoscopic submucosal dissection and endoscopic full-thickness resection. This review aims to provide an overview of the different endoscopic resection techniques and their indications, and summarizes the current recommendations in the recently published guideline of the European Society of Gastrointestinal Endoscopy...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29110039/-endoscopic-and-surgical-treatment-of-early-gastric-and-esophageal-carcinoma
#7
REVIEW
T Haist, M Knabe, A May, D Lorenz
BACKGROUND: The treatment of early gastric (EGC) and esophageal carcinomas (EEC) is an interdisciplinary challenge. The risk of lymph node metastasis (LNM) is the crucial point in choosing the correct treatment option. OBJECTIVE: This article gives an overview of the current treatment options and provides help in choosing the correct therapy. METHOD: Current concepts and therapy algorithms are presented on the basis of a literature review and data from our own center...
November 6, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29106761/a-case-of-diminutive-duodenal-deep-submucosal-invasive-adenocarcinoma-resected-by-endoscopic-mucosal-resection
#8
Naoki Yorita, Yoji Sanomura, Shinji Tanaka
A 50-year-old man underwent esophagogastroduodenoscopy, which revealed a tiny duodenal polypoid tumor 4 mm in diameter in the descending part of the duodenum. The tumor had no depressive area. Narrow-band imaging magnifying endoscopic findings revealed regular surface and vessel patterns. This article is protected by copyright. All rights reserved.
November 6, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29105290/endoscopic-resection-of-large-colorectal-adenomas-clinical-experience-of-a-tertiary-referral-center
#9
Liat Mlynarsky, Shira Zelber-Sagi, Eliaz Miller, Revital Kariv
BACKGROUND: Colorectal cancer is a leading cause for cancer-related mortality. Adenomatous polyps are typically resected endoscopically to prevent cancer while giant and complex polyps are managed surgically. No criteria clearly define the indications for surgical versus endoscopic resection. AIM: To evaluate factors associated with short-term efficacy and safety of endoscopic resection of large (≥20mm) and giant (≥40mm) adenomas. METHODS: Consecutive cases with colonic adenomas larger than 20mm, resected endoscopically were included...
November 4, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29104470/critical-role-of-p53-and-k-ras-in-the-diagnosis-of-early-colorectal-cancer-a-one-year-single-center-analysis
#10
Hui-Ying Lu, Ri-Tian Lin, Guang-Xi Zhou, Tian-Ming Yu, Zhan-Ju Liu
Background: Colorectal cancer (CRC) is strongly associated with colorectal polyps, which has become the third most common cancer in China. In the present study, we revealed the susceptible population and risk factors of colorectal polyps, and analyzed the expression of Ki-67, p53 and K-ras in the intestinal mucosa of patients with colorectal polyps in order to explore their significance in the detection and prognosis of CRC at an early stage. Materials and Methods: Total 801 cases of colorectal polyps were collected during endoscopic resection including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD)...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29103533/diagnosis-and-management-of-barrett-related-neoplasia-in-the-modern-era
#11
REVIEW
Lysandra Voltaggio, Elizabeth A Montgomery
Whereas in the past, pathologists were hesitant to diagnose high-grade dysplasia in patients with Barrett esophagus, because this diagnosis prompted esophagectomy, current international consensus is that endoscopic treatment is the management for high-grade dysplasia and intramucosal carcinoma. Furthermore, many centers advocate endoscopic ablation for low-grade dysplasia. As such, establishing a diagnosis of dysplasia has become the key step; separation between the grades of dysplasia is less critical. This article offers some criteria for separating dysplasia from reactive changes, discusses pitfalls in interpreting endoscopic mucosal resection specimens, and outlines management strategies...
December 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/29101561/non-exposure-simple-suturing-endoscopic-full-thickness-resection-ness-eftr-versus-laparoscopic-wedge-resection-a-randomized-controlled-trial-in-a-porcine-model
#12
Hong Man Yoon, Chan Gyoo Kim, Jong Yeul Lee, Soo-Jeong Cho, Myeong-Cherl Kook, Bang Wool Eom, Keun Won Ryu, Young-Woo Kim, Il Ju Choi
BACKGROUND: Current endoscopic full-thickness resection (EFTR) methods produce transmural communication and expose the tumor to the peritoneum. An EFTR method with a simple suturing technique that does not expose the gastric mucosa to the peritoneum (non-exposure simple suturing, NESS) was recently developed. To date, there have been no prospective studies that compare EFTR with laparoscopic wedge resection in human or animal. The aim of this study was to compare outcomes between NESS-EFTR and laparoscopic wedge resection (LWR) using the linear staplers in a randomized animal study...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29101560/feasibility-and-outcomes-of-underwater-endoscopic-mucosal-resection-for-%C3%A2-%C3%A2-10%C3%A2-mm-colorectal-polyps
#13
Keith Siau, Sauid Ishaq, Sergio Cadoni, Toshio Kuwai, Abdulkani Yusuf, Noriko Suzuki
BACKGROUND: Underwater endoscopic mucosal resection (UEMR) is an emerging strategy for the management of colorectal polyps. We aimed to evaluate the efficacy and safety of UEMR for clinically significant (≥ 10 mm) colorectal polyps. METHODS: We performed a prospective dual-centre study of polyps ≥ 10 mm undergoing UEMR between June 2014 and March 2017. Outcomes measured comprised: (1) completeness of resection at index UEMR, (2) intraprocedural and 30-day complications, (3) rates and predictors of submucosal lift, en bloc resection, polyp/adenoma recurrence and (4) pain score...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29098434/resection-outcomes-and-recurrence-rates-of-endoscopic-submucosal-dissection-esd-and-hybrid-esd-for-colorectal-tumors-in-a-single-italian-center
#14
Reza V Milano, Edi Viale, Michael J Bartel, Chiara Notaristefano, Pier Alberto Testoni
BACKGROUND: Endoscopic submucosal dissection (ESD) and hybrid-ESD techniques are treatment modalities for colorectal neoplasia, although mostly used in the Eastern hemisphere. Only few data on ESD for colorectal neoplasia have been published in the West. We report the outcomes of colorectal ESD and hybrid ESD in a single Italian center. METHODS: We retrospectively evaluated the outcomes of all ESD and hybrid-ESD procedures for colorectal neoplasia performed over the first 2-year experience from a prospectively recorded database...
November 2, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29095708/updates-in-the-management-of-sinonasal-mucosal-melanoma
#15
Meghan M Crippen, Suat Kılıç, Jean A Eloy
PURPOSE OF REVIEW: Sinonasal mucosal melanoma (SNMM) is an aggressive cancer with a poor prognosis. Although there is significant study surrounding the treatment of sinonasal malignancies and cutaneous melanomas, the rarity of this tumor has largely precluded robust outcomes analyses. The authors of this review seek to provide an overview of the recent literature related to the treatment of SNMM with added context from our institutional experience with this disease. RECENT FINDINGS: In the surgical management of sinonasal malignancies and SNMM specifically, resection via endoscopic endonasal technique appears to offer comparable oncologic outcomes versus an open approach...
October 31, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29093627/oval-mucosal-opening-bloc-biopsy-after-incision-and-widening-by-ring-thread-traction-for-submucosal-tumor
#16
Hirohito Mori, Hideki Kobara, Yu Guan, Yasuhiro Goda, Nobuya Kobayashi, Noriko Nishiyama, Tsutomu Masaki
Gastric submucosal tumors (SMTs) less than 2 cm are generally considered benign neoplasms, and endoscopic observation is recommended, but SMTs over 2 cm, 40% of which are gastrointestinal stromal tumors (GISTs), have malignant potential. Although the Japanese Guidelines for GIST recommend partial surgical resection for GIST over 2 cm with malignant potential as well as en bloc large tissue sample to obtain appropriate and large specimens of SMTs, several reports have been published on tissue sampling of SMTs, such as with endoscopic ultrasound sound fine needle aspiration, submucosal tunneling bloc biopsy, and the combination of bite biopsy and endoscopic mucosal resection...
October 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29084075/the-safety-and-efficacy-of-endoscopic-submucosal-dissection-for-early-gastric-cancer-with-concomitant-liver-cirrhosis
#17
Mohamed Barakat, Bhanu Singh, Carolyn Salafia, Saphwat Eskaros
OBJECTIVE/BACKGROUND: Endoscopic submucosal dissection (ESD) allows en bloc resection of lesions with R0 margins; however, it has a higher risk of bleeding and perforation compared with endoscopic mucosal resection. Surgical intervention for early gastric cancer (EGC) has been associated with an increased risk of bleeding in patients with liver cirrhosis (LC). Our aim was to assess the safety and efficacy of ESD in patients with EGC and concomitant LC. PATIENTS AND METHODS: We performed a systematic review of Medline and Cochrane database followed by a pooled data-analysis...
October 27, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29079895/early-esophageal-cancer-with-epidermization-diagnosed-and-treated-with-endoscopic-resection
#18
Satoshi Yamanouchi, Yukiko Sako, Shinsuke Suemitsu, Kousuke Tsukano, Satoshi Kotani, Ryusaku Kusunoki, Youichi Miyaoka, Tatsuya Miyake, Hirofumi Fujishiro, Naruaki Kohge, Tomohiko Yamamoto, Hideyuki Ohnuma
The patient was a 57-year-old man who had undergone endoscopic submucosal dissection for early esophageal cancer (distance from incisor tooth, 30 cm) when he was 50 years of age. Pathological findings showed squamous cell carcinoma invading the lamina muscularis mucosae and mild lymphatic invasion. Considering the possibility of lymph node metastasis and distant metastasis, we administered radiation chemotherapy (CDDP+ 5-FU, total radiation 41.4 Gy) in the same year. Two years later, follow-up endoscopy revealed a white, flat, elevated lesion in the thoracic esophagus (distance from incisor tooth, 36 cm) that was not stained by Lugol's iodine...
October 27, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29078688/endoscopic-mucosal-ablation-and-resection-of-barrett-s-esophagus-and-related-diseases
#19
REVIEW
Juan A Muñoz-Largacha, Virginia R Litle
The prevalence of gastroesophageal reflux disease as well as the incidence of Barrett's esophagus (BE) has increased in the Western world over the last decades. The chronic reflux of gastric secretions injuries the esophageal mucosa and triggers cellular and molecular changes inducing the transformation of the normal squamous mucosa into columnar metaplastic epithelium. BE is a premalignant condition that can progress to low-grade dysplasia, high-grade dysplasia and ultimately esophageal adenocarcinoma. An early diagnosis of dysplastic changes and the adoption of appropriate therapeutic approaches are essential to improve patient outcomes and survival...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29075796/-surgical-management-for-early-stage-gastric-cancer
#20
REVIEW
K Ludwig, D Möller, J Bernhardt
BACKGROUND: In the last decade the implementation of the new technique of endoscopic submucosal dissection (ESD) and the rapid progression of laparoscopic gastric cancer (LAG) resection with an adequate lymphadenectomy (LAD) have played an increasing role in the treatment of patients with early stage gastric cancer (EGC). OBJECTIVE: A systematic review of the currently available data in the literature was carried out to evaluate the contemporary surgical management for treatment of EGC...
October 26, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
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