keyword
https://read.qxmd.com/read/38537086/effect-of-dexmedetomidine-on-the-incidence-of-postoperative-acute-kidney-injury-in-living-donor-liver-transplantation-recipients-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Hye-Mee Kwon, Sa-Jin Kang, Sang-Bin Han, Jae Hwan Kim, Sung-Hoon Kim, In-Gu Jun, Jun-Gol Song, Gyu-Sam Hwang
BACKGROUND: Acute kidney injury (AKI) is one of the most common complications after living-donor liver transplantation (LDLT) that has great impact on recipient and graft outcomes. Dexmedetomidine is reported to decrease the incidence of AKI. In the current study, we investigated whether intraoperative dexmedetomidine infusion would reduce the AKI following LDLT. MATERIAL AND METHODS: In total, 205 adult patients undergoing elective LDLT were randomly assigned to the dexmedetomidine group (n=103) or the control group (n=102)...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38533301/impact-and-prevalence-of-comorbidities-and-complications-on-the-severity-of-covid-19-in-association-with-age-gender-obesity-and-pre-existing-smoking-a-meta-analysis
#2
REVIEW
Soulandi Djorwé, Amale Bousfiha, Néhémie Nzoyikorera, Joseph Nyandwi, Bellamine Kawthar, Abderrahim Malki
BACKGROUND: COVID-19 patients usually present multiple comorbidities and complications associated with severe forms of SARS-CoV-2 infection. This study aimed to assess the risk factors and prevalence of comorbidities and complications contributing to the severity of COVID-19. METHODS: This meta-analysis was performed according to PRISMA guidelines. We searched various databases, including PubMed, Google Scholar, and Scopus (between 2020 and 2023), for eligible studies for this meta-analysis...
2024: BioMedicine
https://read.qxmd.com/read/38533295/hemodynamic-determinants-of-cardiac-surgery-associated-acute-kidney-injury
#3
JOURNAL ARTICLE
Sevag Demirjian, Faisal Bakaeen, W H Wilson Tang, Chase Donaldson, Jon Taliercio, Anne Huml, Crystal A Gadegbeku, A Marc Gillinov, Steven Insler
OBJECTIVES: Examine the: 1) relative role of hemodynamic determinants of acute kidney injury (AKI) obtained in the immediate postcardiac surgery setting compared with established risk factors, 2) their predictive value, and 3) extent mediation via central venous pressure (CVP) and mean arterial pressure (MAP). DESIGN: Retrospective observational study. The main outcome of the study was moderate to severe AKI, per kidney disease: improving global outcomes, within 14 days of surgery...
April 2024: Critical care explorations
https://read.qxmd.com/read/38531564/investigation-of-renal-perfusion-and-pathological-changes-in-patients-with-acute-kidney-disease-and-tubulointerstitial-nephritis-using-intravoxel-incoherent-motion-and-arterial-spin-labelling-mri-a-prospective-observational-study-protocol
#4
JOURNAL ARTICLE
Jiajia Liu, Rui Wang, Jianxing Qiu, Tao Su
INTRODUCTION: Acute kidney injury (AKI) is a critical condition with a complex aetiology and different outcomes, where haemodynamic dysfunction, renal hypoperfusion and inflammation serve as key contributors to its development and progression. Early and accurate diagnosis is vital for initiating targeted treatments like fluid resuscitation, vasoactive agents or steroid therapy, which are essential for improving patient outcomes. Intravoxel incoherent motion (IVIM) MRI assesses both capillary perfusion and tissue water diffusion, while arterial spin labelling (ASL) MRI measures renal blood flow without the need for contrast...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38525502/pyxinol-fatty-acid-ester-derivatives-j16-against-aki-by-selectively-promoting-m1-transition-to-m2c-macrophages
#5
JOURNAL ARTICLE
Yaru Wang, Changcheng Li, Jingyi Chen, Xiaoli Cui, Binghuan Wang, Yuezeng Wang, Dayu Wang, Jinping Liu, Jing Li
Acute kidney injury (AKI) is a common, multicause clinical condition that, if ignored, often progresses to chronic kidney disease (CKD) and end-stage kidney disease, with a mortality rate of 40-50%. However, there is a lack of universal treatment for AKI. Inflammation is the basic pathological change of early kidney injury, and inflammation can exacerbate AKI. Macrophages are the primary immune cells involved in the inflammatory microenvironment of kidney disease. Therefore, regulating the function of macrophages is a crucial breakthrough for the AKI intervention...
March 25, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38524020/an-investigation-of-contrast-induced-acute-kidney-injury-in-patients-undergoing-percutaneous-coronary-intervention-a-cross-sectional-study-from-pakistan
#6
JOURNAL ARTICLE
Zair Hassan, Usha Kumari, Umaima Wasim, Sanjana Kumari, Nikhil Reddy Daggula, Salim Surani, Hazir Ullah
Background and objective Contrast-induced acute kidney injury (CIAKI) is a complication observed among individuals undergoing primary percutaneous coronary intervention (PCI) and is associated with high morbidity and mortality rates. It is characterized by an elevation in serum creatinine (SCr) levels >0.5 mg/dl or a 50% relative increase in SCr from the baseline value following exposure to contrast within a 48- to 72-hour timeframe, in the absence of any alternative causes for acute kidney injury (AKI)...
February 2024: Curēus
https://read.qxmd.com/read/38523999/filling-in-the-gaps-ethylene-glycol-poisoning-presenting-with-isolated-lactate-and-osmolar-gaps
#7
Caden Quintanilla, Justin Panthappattu, Davood Hosseini, Karan Omidvari
Ethylene glycol (EG) is an organic compound used in antifreeze. In 2020 alone, there were 5,277 EG exposures, with only 617 reported as intentional ingestions. Therefore, encountering EG toxicity is rare; however, it is essential to identify it promptly based on a focused history, exam, and rapid identification of commonly associated EG-induced metabolic derangements. If the diagnosis is not made within 12 hours of ingestion or exposure, severe morbidity and mortality can occur. Previous reports of EG poisoning have occurred in the setting of a lactate gap (LG) and osmolar gap (OG); however, they also had commonly associated findings of EG toxicity such as high anion gap acidosis (HAGMA), acute kidney injury (AKI), hypocalcemia, calcium oxalate stones, and suggestive histories of EG ingestion...
February 2024: Curēus
https://read.qxmd.com/read/38517149/digital-variance-angiography-in-patients-undergoing-lower-limb-arterial-recanalization-cost-effectiveness-analysis-within-the-english-healthcare-setting
#8
JOURNAL ARTICLE
Amir Ansaripour, Eoin Moloney, Michael Branagan-Harris, Lorenzo Patrone, Mehdi Javanbakht
Aim: Digital variance angiography (DVA) is a recently developed image processing method capable of improving image quality compared with the traditionally used digital subtraction angiography (DSA), among patients undergoing lower limb x-ray angiography. This study aims to explore the potential cost-effectiveness of DVA from an English National Health Service perspective. Materials & methods: A two-part economic model, consisting of a decision tree and a Markov model, was developed to consider the costs and health outcomes associated with the use of DVA as part of current practice imaging, compared with x-ray angiography using standard DSA...
March 22, 2024: Journal of Comparative Effectiveness Research
https://read.qxmd.com/read/38516472/nephrological-detrimental-impacts-resulting-from-novel-immunotherapy-drugs-used-in-the-treatment-of-cancer-a-systematic-review
#9
REVIEW
Amisha Jaiswal, Kainaat Shergill, Kusalik Boppana, Naiela E Almansouri, Saloni Bakkannavar, Youmna Faheem, Tuheen Sankar Nath
The most recent advancements in cancer therapy center on efficiently and conveniently enhancing a patient's natural immune system. Immune checkpoint inhibitors (ICIs) are antibodies that target cytotoxic thymus (T) lymphocyte antigen-4 (CTLA-4) and its receptor. They function by stimulating T-cell activity against malignancies. Immune-related adverse events (irAEs) are a distinct class of inflammatory side effects that are specific to a given organ. Antineoplastic medications can impact any part of the kidney, leading to the development of proteinuria, hypertension, electrolyte abnormalities, glomerulonephritis, and both acute and chronic interstitial nephritis...
February 2024: Curēus
https://read.qxmd.com/read/38516106/risk-of-acute-kidney-injury-in-critically-ill-patients-with-covid-19-compared-with-seasonal-influenza-a-retrospective-cohort-study
#10
JOURNAL ARTICLE
Pauline Yeung Ng, April Ip, Andrew Kei-Yan Ng, Simon Wai-Ching Sin, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Desmond Yat-Hin Yap
BACKGROUND: The SARS-CoV-2 virus can bind to angiotensin-converting enzyme 2 receptors on host renal cells and may cause acute kidney injury (AKI). The comparative risks of AKI in patients severely ill with COVID-19 and influenza A have not been examined. METHODS: This is a retrospective cohort study including patients with positive PCR results for SARS-CoV-2 or influenza A virus admitted to the intensive care units (ICUs) of 15 public hospitals in Hong Kong between 1st January 2013 and 30th April 2023...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38512840/acute-kidney-injury-in-hospitalized-children-with-proteinuria-a-multicenter-retrospective-analysis
#11
JOURNAL ARTICLE
Katelyn H Baggett, Tomas Manghi, Vonn Walter, Neal J Thomas, Michael A Freeman, Conrad Krawiec
BACKGROUND AND OBJECTIVE: Acute kidney injury (AKI) is a common complication in hospitalized pediatric patients. Previous studies focused on adults found that proteinuria detected during an admission urinalysis is fit to serve as an indicator for AKI and associated clinical outcomes. The objective of this study is to evaluate if proteinuria on the first day of hospital services in hospitalized children is associated with AKI, need for renal replacement therapy, shock and/or antibiotic use, critical care services, and all-cause mortality at 30 days, hypothesizing that it is associated with these outcomes...
2024: PloS One
https://read.qxmd.com/read/38511219/parental-obesity-predisposes-offspring-to-kidney-dysfunction-and-increased-susceptibility-to-ischemia-reperfusion-injury-in-a-sex-dependent-manner
#12
JOURNAL ARTICLE
Jussara M do Carmo, John E Hall, Xuemei Dai, Nikaela Aitken, Kylie Larson, Emilio M Luna-Suarez, Zhen Wang, Ana C M Omoto, Alan Mouton, Xuan Li, Luzia N S Furukawa, Viktoria Woronik, Alexandre A da Silva
Although obesity is recognized as a risk factor for cardiorenal and metabolic diseases, the impact of parental obesity on the susceptibility of their offspring to renal injury at adulthood is unknown. We examined the impact of parental obesity on offspring kidney function, morphology, and markers of kidney damage after acute kidney injury (AKI). Offspring from normal (N) diet-fed C57BL/6J parents were fed either N (NN) or a high fat (H) diet (NH) from weaning until adulthood. Offspring from obese H diet-fed parents were fed N (HN) or H diet (HH) after weaning...
March 21, 2024: American Journal of Physiology. Renal Physiology
https://read.qxmd.com/read/38510762/acute-kidney-injury-in-patients-undergoing-extracorporeal-membrane-oxygenation-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
Aswin Surjit, Bipi Prasannan, Jobin Abraham, Anuroop Balagopal, Vavullipathy Narayanan Unni
AIMS AND BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a mode of extracorporeal therapy to support oxygenation of patients with severe cardiac or respiratory failure. Studies have shown that acute kidney injury (AKI) can worsen the outcome in these patients. This study aims to assess the incidence and outcome of AKI in patients on ECMO support. MATERIALS AND METHODS: This retrospective study included 64 patients who underwent ECMO for more than 24 hours...
January 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38509215/extracellular-vesicles-secreted-from-mesenchymal-stem-cells-ameliorate-renal-ischemia-reperfusion-injury-by-delivering-mir-100-5p-targeting-fkbp5-akt-axis
#14
JOURNAL ARTICLE
Guo Chen, Xinyuan Li, Xiang Zhou, Yang Li, Haitao Yu, Xiang Peng, Xuesong Bai, Chunlin Zhang, Zhenwei Feng, Yuhua Mei, Li Li, Yu Liu, Xin Gou, Yuanbin Jiang
The incidence of acute kidney injury (AKI) due to ischemia-reperfusion (IR) injury is increasing. There is no effective treatment for AKI, and because of this clinical challenge, AKI often progresses to chronic kidney disease, which is closely associated with poor patient outcomes and high mortality rates. Small extracellular vesicles from human umbilical cord mesenchymal stem cells (hUCMSC-sEVs) play increasingly vital roles in protecting tissue function from the effects of various harmful stimuli owing to their specific biological features...
March 20, 2024: Scientific Reports
https://read.qxmd.com/read/38509206/a-pilot-study-to-explore-patterns-and-predictors-of-delayed-kidney-decline-after-cardiopulmonary-bypass
#15
JOURNAL ARTICLE
Ahmed Zaky, Duraid S Younan, Bradley Meers, David Miller, Ryan L Melvin, David Benz, James Davies, Brent Kidd, Mali Mathru, Ashita Tolwani
There is no current consensus on the follow up of kidney function in patients undergoing cardiopulmonary bypass (CPB). The main objectives of this pilot study is to collect preliminary data on kidney function decline encountered on the first postoperative visit of patients who have had CPB and to identify predictors of kidney function decline post hospital discharge. Design: Retrospective chart review. Adult patients undergoing open heart procedures utilizing CPB. Patient demographics, type of procedure, pre-, intra-, and postoperative clinical, hemodynamic echocardiographic, and laboratory data were abstracted from electronic medical records...
March 20, 2024: Scientific Reports
https://read.qxmd.com/read/38504176/burden-and-risk-profile-of-acute-kidney-injury-in-severe-covid-19-pneumonia-admissions-a-finding-from-jimma-university-medical-center-ethiopia
#16
JOURNAL ARTICLE
Ebrahim Kelil Umer, Abel Tezera Abebe, Yabets Tesfaye Kebede, Nardos Tilahun Bekele
BACKGROUND: Acute kidney injury (AKI) is a serious complication of the Corona Virus Disease of 2019 (COVID-19). However, data on its magnitude and risk factors among hospitalized patients in Ethiopia is limited. This study aimed to determine the magnitude of AKI and associated factors among patients admitted for severe COVID-19 pneumonia. METHODS: An institution-based retrospective cross-sectional study was conducted among 224 patients admitted to Jimma University Medical Center in Ethiopia for severe COVID-19 pneumonia from May 2020 to December 2021...
March 20, 2024: BMC Nephrology
https://read.qxmd.com/read/38500492/transient-acute-kidney-injury-after-chimeric-antigen-receptor-t-cell-therapy-in-patients-with-hematological-malignancies
#17
JOURNAL ARTICLE
Juan León-Román, Gloria Iacoboni, Sheila Bermejo, Cecilia Carpio, Mónica Bolufer, Clara García-Carro, Mario Sánchez-Salinas, Carla Alonso-Martínez, Oriol Bestard, Pere Barba, María José Soler
BACKGROUND: Acute kidney injury (AKI) occurs in 30% of patients infused with chimeric antigen receptor (CAR) T-cells. The purpose of this study was to identify risk factors and long-term outcomes after AKI in patients who received CAR T-cell therapy. METHODS: Medical records of 115 adult patients with R/R hematological malignancies treated with CD19-targeted CAR T-cells at Vall d'Hebron University Hospital between July 2018 and May 2021. Baseline demographic data including age, gender, ethnicity, body mass index (BMI), and co-morbidities, as well as the type of hematological neoplasia and prior lines of therapy were collected...
March 2024: Clinical Kidney Journal
https://read.qxmd.com/read/38499002/acute-and-chronic-kidney-dysfunction-and-prognosis-following-thrombectomy-for-ischemic-stroke
#18
JOURNAL ARTICLE
Mickaël Bobot, Jean-François Hak, Barbara Casolla, Jean-Daniel Dehondt, Stéphane Burtey, Emilie Doche, Laurent Suissa
INTRODUCTION: Patients with Chronic Kidney Disease (CKD) have an increased risk of stroke and CKD seems associated with worse outcome after a stroke. The main objective of our study RISOTTO was to evaluate the influence of CKD and Acute Kidney Injury (AKI) on the clinical outcome and mortality of ischemic stroke patients after thrombolysis and/or thrombectomy. METHODS: This multicenter cohort study included patients in the acute phase of ischemic stroke due to a large artery occlusion managed by thrombectomy...
March 18, 2024: American Journal of Nephrology
https://read.qxmd.com/read/38496155/profile-of-acute-kidney-injury-in-the-pediatric-age-group-in-a-tertiary-care-hospital-a-prospective-observational-study
#19
JOURNAL ARTICLE
Ishan Kapil, Anil Kumar Goel, Manas R Sahoo
BACKGROUND AND OBJECTIVES: Acute kidney injury (AKI) is a menace in the pediatric intensive care unit (PICU) and is responsible for significant morbidity and mortality all over the world. There are limited data available on pediatric AKI in central India. Our primary objective is to determine the clinical, etiological, and outcome profile of AKI in the pediatric age group of 3 months to 15 years admitted to the All India Institute of Medical Sciences (AIIMS), Raipur. The secondary objective(s) is to predict the association of mortality in children diagnosed with AKI and to estimate the number of patients developing chronic kidney disease (CKD) at three-month follow-up...
February 2024: Curēus
https://read.qxmd.com/read/38495365/advancing-community-care-and-access-to-follow-up-after-acute-kidney-injury-hospitalization-design-of-the-after-aki-randomized-controlled-trial
#20
JOURNAL ARTICLE
Meha Bhatt, Eleanor Benterud, Taylor Palechuk, Coralea Bignell, Nasreen Ahmed, Kerry McBrien, Matthew T James, Neesh Pannu
BACKGROUND: Acute kidney injury (AKI) is a common complication among hospitalized patients with long-term implications including chronic kidney disease (CKD). Although models are available to predict the risk of advanced CKD after AKI, there is limited evidence regarding follow-up for patients with AKI after hospital discharge, resulting in variable follow-up care. A risk-stratified follow-up approach may improve appropriateness and efficiency of management for CKD among patients at risk of declining kidney function following AKI...
2024: Canadian Journal of Kidney Health and Disease
keyword
keyword
13400
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.