keyword
https://read.qxmd.com/read/38524040/lumbar-subarachnoid-peritoneal-shunting-deteriorates-superficial-siderosis-associated-with-a-dural-defect
#1
Narutada Ando, Yusuke Nakazawa, Takeshi Miyata, Takenori Ogura, Wataru Shiraishi, Taketo Hatano
Superficial siderosis is a disease in which hemosiderin is deposited under the leptomeninges and subpial layers of hindbrain structures, e.g., the cerebellum, brainstem, and eighth cranial nerve. The main symptoms of superficial siderosis are cerebellar ataxia, hearing loss, cognitive decline, and myelopathy. The activities of daily living of patients with superficial siderosis are severely impaired due to the progressive symptoms. Here, we report a patient with superficial siderosis whose symptoms deteriorated after lumbar subarachnoid-peritoneal (L-P) shunt surgery...
February 2024: Curēus
https://read.qxmd.com/read/38519448/transcerebellar-ventriculoperitoneal-shunt-for-management-of-presumed-arachnoid-diverticulum-in-the-fourth-ventricle-of-a-dog
#2
Sophie Wyatt, Joe Fenn, Elsa Beltran
OBJECTIVE: To describe the approach for placement of a transcerebellar fourth ventriculoperitoneal shunt for management of presumed fourth ventricle arachnoid diverticulum and secondary obstructive hydrocephalus of a dog. To describe the outcome of this procedure. STUDY DESIGN: Case report. ANIMALS: Male entire English springer spaniel, 3 years 9 months of age. METHODS: The dog was initially presented for management of acute, progressive, and multifocal brainstem and forebrain dysfunction...
March 22, 2024: Veterinary Surgery
https://read.qxmd.com/read/38510885/the-top-100-most-cited-journal-articles-on-hydrocephalus
#3
REVIEW
Laurel A Seltzer, Mitchell W Couldwell, R Shane Tubbs, C J Bui, Aaron S Dumont
Hydrocephalus represents a significant burden of disease, with more than 383,000 new cases annually worldwide. When the magnitude of this condition is considered, a centralized archive of pertinent literature is of great clinical value. From a neurosurgical standpoint, hydrocephalus is one of the most frequently treated conditions in the field. The focus of this study was to identify the top 100 journal articles specific to hydrocephalus using bibliometric analysis. Using the Journal of Citation Report database, 10 journals were identified...
February 2024: Curēus
https://read.qxmd.com/read/38496536/molecular-signatures-of-normal-pressure-hydrocephalus-a-large-scale-proteomic-analysis-of-cerebrospinal-fluid
#4
Aida Kamalian, Siavash Shirzadeh Barough, Sara G Ho, Marilyn Albert, Mark G Luciano, Sevil Yasar, Abhay Moghekar
Given the persistent challenge of differentiating idiopathic Normal Pressure Hydrocephalus (iNPH) from similar clinical entities, we conducted an in-depth proteomic study of cerebrospinal fluid (CSF) in 28 shunt-responsive iNPH patients, 38 Mild Cognitive Impairment (MCI) due to Alzheimer's disease, and 49 healthy controls. Utilizing the Olink Explore 3072 panel, we identified distinct proteomic profiles in iNPH that highlight significant downregulation of synaptic markers and cell-cell adhesion proteins. Alongside vimentin and inflammatory markers upregulation, these results suggest ependymal layer and transependymal flow dysfunction...
March 4, 2024: bioRxiv
https://read.qxmd.com/read/38486858/improve-the-diagnosis-of-idiopathic-normal-pressure-hydrocephalus-by-combining-abnormal-cortical-thickness-and-ventricular-morphometry
#5
JOURNAL ARTICLE
Yifeng Yang, Meijing Yan, Xiao Liu, Shihong Li, Guangwu Lin
BACKGROUND: The primary imaging markers for idiopathic Normal Pressure Hydrocephalus (iNPH) emphasize morphological measurements within the ventricular system, with no attention given to alterations in brain parenchyma. This study aimed to investigate the potential effectiveness of combining ventricular morphometry and cortical structural measurements as diagnostic biomarkers for iNPH. METHODS: A total of 57 iNPH patients and 55 age-matched healthy controls (HC) were recruited in this study...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38467373/the-potential-role-of-the-gut-microbiota-in-the-development-of-idiopathic-normal-pressure-hydrocephalus-inph-a-matter-or-coincidence
#6
JOURNAL ARTICLE
Felice Buscemi, Fabio Torregrossa, Giovanni Grasso
No abstract text is available yet for this article.
March 9, 2024: World Neurosurgery
https://read.qxmd.com/read/38464824/comparing-the-long-term-cardiovascular-outcomes-of-lumbo-peritoneal-ventriculo-peritoneal-or-non-shunting-treatment-after-idiopathic-normal-pressure-hydrocephalus-a-nationwide-retrospective-cohort-study
#7
JOURNAL ARTICLE
Cheng-Di Chiu, Po-Fan Chiu, Chih-Ying Wu, Hei-Tung Yip, You-Pen Chiu, Hui-Ru Ji, Kai-Cheng Hsu, Fuu-Jen Tsai, Robert Chen-Hao Chang
Purpose: With advances in medical technology, the average lifespan has increased, leading to a growing significance of idiopathic normal pressure hydrocephalus (iNPH), particularly in the elderly population. Most patients with iNPH have been treated either with ventriculo-peritoneal shunts (VPS) or conservative measures. However, lumbo-peritoneal shunts (LPS) have emerged as an alternative treatment option for iNPH in recent decades, extensive research still lacks comparing outcomes with LPS to those with VPS or non-surgical treatment...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/38462633/the-glymphatic-system-in-migraine-and-other-headaches
#8
REVIEW
Maria Grazia Vittorini, Aysenur Sahin, Antonin Trojan, Sevil Yusifli, Tamta Alashvili, Gonçalo V Bonifácio, Ketevan Paposhvili, Viktoria Tischler, Christian Lampl, Simona Sacco
Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial vessels and communicating with the subarachnoid space. It is separated from vessels by the blood brain barrier and from brain tissue by the endfeet of the astrocytes rich in aquaporin 4, a membrane protein which controls the water flow along the perivascular space...
March 11, 2024: Journal of Headache and Pain
https://read.qxmd.com/read/38457801/a-ventriculomegaly-feature-computational-pipeline-to-improve-the-screening-of-normal-pressure-hydrocephalus-on-ct
#9
JOURNAL ARTICLE
Sharada Kadaba Sridhar, Rui Kuang, Jen Dysterheft Robb, Uzma Samadani
OBJECTIVE: The objective of this study was to develop a computational pipeline that extracts objective features of ventriculomegaly from non-contrast CT (NCCT) for the accurate classification of idiopathic normal pressure hydrocephalus (NPH) from headache controls (HCs), Alzheimer's dementia (AD), and posttraumatic encephalomalacia (PTE). METHODS: Patients with possible NPH (n = 79) and a subset with definite NPH (DefNPH; n = 29) were retrospectively identified in the Veterans Affairs Informatics and Computing Infrastructure system, along with the AD (n = 62), PTE (n = 53), and HC (n = 59) cohorts...
March 8, 2024: Journal of Neurosurgery
https://read.qxmd.com/read/38454478/freezing-of-gait-in-idiopathic-normal-pressure-hydrocephalus
#10
JOURNAL ARTICLE
Carl-Johan Kihlstedt, Jan Malm, Alfonso Fasano, David Bäckström
BACKGROUND: Reports of freezing of gait (FoG) in idiopathic normal pressure hydrocephalus (iNPH) are few and results are variable. This study's objective was to evaluate the frequency of FoG in a large cohort of iNPH patients, identify FoG-associated factors, and assess FoG's responsiveness to shunt surgery. METHODS: Videotaped standardized gait protocols with iNPH patients pre- and post-shunt surgery (n = 139; median age 75 (71-79) years; 48 women) were evaluated for FoG episodes by two observers (Cohens kappa = 0...
March 8, 2024: Fluids and Barriers of the CNS
https://read.qxmd.com/read/38450246/17-years-of-experience-with-shunt-systems-in-normal-pressure-hydrocephalus-from-differential-pressure-to-gravitational-valves
#11
JOURNAL ARTICLE
Julian Zipfel, Cristina Kohlmann-Dell'Acqua, Susan Noell, Leonidas Trakolis
OBJECTIVE: Complication rate of shunting for normal pressure hydrocephalus (NPH) has significantly improved over the last decades. Especially the use of overdrainage protection has reduced the incidence of subdural hematoma and collections. However, gravitational valves were associated with other complications of shunt dysfunction. We present our 17 years of experience with patients with normal pressure hydrocephalus who changed from a differential pressure valve to a gravitational valve system...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38444692/pleomorphic-adenoma-of-the-parotid-gland-concomitant-with-tuberculosis-infection-a-case-report-and-review-of-the-literature
#12
Dorra Chiboub, Nadia Romdhane, Esma Jameleddine, Emna Rejeb, Fatma Khanchel, Raja Jouini, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek
Tuberculosis of the salivary glands and particularly of the parotid gland is a localization that remains rare even in endemic countries. The association of intra parotid tuberculosis with a benign tumor has been found only in rare cases in literature. A 50-year-old woman with a history of normal pressure hydrocephalus treated surgically, non-smoker, presented with a right parotid swelling progressively increasing in size for 3 years. Clinical examination revealed a 4 cm long, firm, mobile, painless parotid swelling without inflammatory signs and without accessory lymphadenopathy...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38443374/functional-analysis-of-the-human-perivascular-subarachnoid-space
#13
JOURNAL ARTICLE
Per Kristian Eide, Geir Ringstad
The human subarachnoid space harbors the cerebrospinal fluid, which flows within a landscape of blood vessels and trabeculae. Functional implications of subarachnoid space anatomy remain far less understood. This study of 75 patients utilizes a cerebrospinal fluid tracer (gadobutrol) and consecutive magnetic resonance imaging to investigate features of early (i.e. within 2-3 h after injection) tracer propagation within the subarachnoid space. There is a time-dependent perivascular pattern of enrichment antegrade along the major cerebral artery trunks; the anterior-, middle-, and posterior cerebral arteries...
March 5, 2024: Nature Communications
https://read.qxmd.com/read/38440378/utilizing-kinematic-analysis-of-postural-instability-as-an-objective-measure-to-aid-in-distinguishing-between-normal-pressure-hydrocephalus-and-parkinson-s-disease
#14
JOURNAL ARTICLE
Jacob T Hanson, Luke T Sabal, James N Jean, Alec Jonason, Reid Johnson, Thomas Lisko, Yeng Moua, Robert A McGovern
OBJECTIVE: Patients with normal pressure hydrocephalus (NPH) and Parkinson's Disease (PD) can clinically appear quite similar at baseline evaluation. We sought to investigate the use of kinematic assessment of postural instability (PI) using inertial measurement units (IMUs) as a mechanism of differentiation between the two disease processes. METHODS: 20 patients with NPH, 55 patients with PD, and 56 age-matched, healthy controls underwent quantitative pull test examinations while wearing IMUs at baseline...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38438818/symptoms-and-signs-did-not-predict-outcome-after-surgery-a-prospective-study-of-143-patients-with-idiopathic-normal-pressure-hydrocephalus
#15
JOURNAL ARTICLE
Kerstin Andrén, Carsten Wikkelsø, Katarina Laurell, Lena Kollén, Per Hellström, Mats Tullberg
OBJECTIVE: To determine the utility of symptoms, signs, comorbidities and background variables for the prediction of outcome of treatment in iNPH. METHODS: A prospective observational study of consecutively included iNPH patients, who underwent neurological, physiotherapeutic and neuropsychological assessments before and after shunt surgery. The primary outcome measure was the total change on the iNPH scale, and patients were defined as improved postoperatively if they had improved by at least five points on that scale...
March 5, 2024: Journal of Neurology
https://read.qxmd.com/read/38437677/management-of-shunt-dysfunction-using-noninvasive-intracranial-pressure-waveform-monitoring-illustrative-case
#16
JOURNAL ARTICLE
Raphael Bertani, Caio Perret, Stefan Koester, Paulo Santa Maria, Savio Batista, Sophia de Andrade Cavicchioli, Sany Tomomi de Almeida Rocha Arita, Ruy Monteiro, Gianne Lucchesi, Fernando Augusto Vasconcellos, Matheus Miranda, Wellingson Silva Paiva, Fernando Gomes Pinto
BACKGROUND: Normal pressure hydrocephalus (NPH) treatment consists of using valves for drainage, as it is for hydrocephalus in general. Despite this, complications can occur, putting the patient at risk, and neurological monitoring is crucial. OBSERVATIONS: A 61-year-old male, who had been diagnosed with NPH 3 years prior and was being treated with a ventriculoperitoneal shunt with a programmable valve, presented to the emergency department because of a traumatic brain injury due to a fall from standing height...
March 4, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38420055/normal-pressure-hydrocephalus-like-appearance-in-myotonic-dystrophy-type-1
#17
Asuka Suzuki, Koji Hayashi, Yuka Nakaya, Maho Hayashi, Kouji Hayashi, Yasutaka Kobayashi, Mamiko Sato
Myotonic dystrophy type 1 (DM1) is one of the monogenic neurological diseases that neurologists most often experience. DM1 can develop several symptoms, including muscle weakness, gait disturbance, urinary incontinence, and cognitive decline. Other hand, normal pressure hydrocephalus (NPH) is more frequent in the elderly population and is characterized by a triad of symptoms, gait disturbance, urinary urge incontinence, and cognitive decline. Therefore, some symptoms overlap between DM1 and NPH. In this report, we described a case of DM1 that presented with a triad of NPH, and NPH-like changes in brain images...
January 2024: Curēus
https://read.qxmd.com/read/38419649/corrigendum-comparison-of-cerebrospinal-fluid-space-between-probable-normal-pressure-hydrocephalus-and-alzheimer-s-disease
#18
Hongliang Li, Chunyan Liu, Hong Tai, Youping Wei, Taizhong Shen, Qiong Yang, Keyang Zheng, Yan Xing
[This corrects the article DOI: 10.3389/fnagi.2023.1241237.].
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38393959/neuronal-pentraxin-2-correlates-with-neurodegeneration-but-not-cognition-in-idiopathic-normal-pressure-hydrocephalus-inph
#19
JOURNAL ARTICLE
Megha Patel, Yifan Zhang, Mei-Fang Xiao, Paul Worley, Abhay Moghekar
AIM OF THE STUDY: Neuronal pentraxin-2 (NPTX2) is a synaptic protein responsible for modulating plasticity at excitatory synapses. While the role of NPTX2 as a novel synaptic biomarker in cognitive disorders has been elucidated recently, its role in idiopathic normal pressure hydrocephalus (iNPH) is not yet understood. CLINICAL RATIONALE FOR STUDY: To determine if NPTX2 predicts cognition in patients with iNPH, and whether it could serve as a predictive marker for shunt outcomes...
February 23, 2024: Neurologia i Neurochirurgia Polska
https://read.qxmd.com/read/38373634/clinical-features-of-pasteurellosis-without-an-animal-bite-or-scratch-in-comparison-with-bite-scratch-pasteurellosis
#20
JOURNAL ARTICLE
Tsubasa Asaeda, Takashi Ueda, Yasuhiro Nozaki, Yasushi Murakami, Mika Morosawa, Hiroko Inaba, Hitoshi Ogashiwa, Miki Doi, Kazuhiko Nakajima, Manabu Shirakawa, Akifumi Nakamura, Naoto Ikeda, Yuya Sugiyama, Yoshihiro Wada, Takahiro Ito, Yoshio Takesue
Pasteurellosis is a common zoonotic infection that occurs after an animal bite or scratch (B/S). We compared the clinical features of six patients with non-B/S pasteurellosis with those of 14 patients with B/S infections. Pasteurella multocida was identified with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in all six non-B/S infections, whereas 13 of the 14 B/S infections were identified with diagnostic kits. The non-B/S infections were pneumonia (n = 3), skin and soft tissue infections (n = 2), and bacteremia (n = 1)...
February 17, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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