keyword
https://read.qxmd.com/read/38451439/concomitant-polymyalgia-rheumatica-and-giant-cell-arteritis-associated-with-cystic-echinococcosis-a-rare-geriatric-case
#21
JOURNAL ARTICLE
Bahar Bektan Kanat, Gulru Ulugerger Avci, Tevhide Betul Icli, Alper Doventas
INTRODUCTION: Parasitic infections could be an important triggering factor for autoimmune diseases. We present a clinical case of concomitant polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) induced with cystic echinococcosis (CE). CASE PRESENTATION: A 74-year-old male was admitted with a 2-month history of progressive pain at the shoulders and hip, movement restriction, and constitutional symptoms. As a result of the examinations performed due to rheumatological complaints, PMR and GCA were diagnosed...
March 7, 2024: Acta Parasitologica
https://read.qxmd.com/read/38450427/comment-on-treatment-of-giant-cell-arteritis-with-ultra-short-glucocorticoids-and-tocilizumab-the-role-of-imaging-in-a-prospective-observational-study
#22
JOURNAL ARTICLE
https://read.qxmd.com/read/38449952/through-the-eyes-of-uncertainty-giant-cell-arteritis-and-lyme-neuroborreliosis-in-a-story-of-vision-loss
#23
Leo Wan, Audrey Yan, Erin Reese, John Thomas, Mark Kissinger
Acute vision loss is a prevalent clinical manifestation associated with a broad spectrum of differential diagnoses, encompassing demyelinating diseases, neoplastic processes, autoimmune disorders, and infectious conditions. A rare but noteworthy infectious etiology contributing to acute vision loss is neurological Lyme disease (Lyme neuroborreliosis)-induced optic neuritis. Lyme disease, a vector-borne illness caused by the spirochete Borrelia burgdorferi , has the potential to affect multiple physiological systems and unfolds in three distinct stages...
February 2024: Curēus
https://read.qxmd.com/read/38449885/low-incidence-of-malignancy-in-patients-with-suspected-polymyalgia-rheumatica-or-giant-cell-arteritis-examined-with-fdg-pet-ct
#24
JOURNAL ARTICLE
Tanja Fromberg Gorlen, Jane Maestri Brittain, Mikkel Østergaard, Barbara Malene Fischer, Uffe Møller Døhn, Lene Terslev
INTRODUCTION: The need to systematically examine patients suspected of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) for malignancy is controversial. The aim of this study was to assess the frequency of malignancy in patients with suspected PMR and/or GCA who have been referred to a 2-deoxy-2-[18 F]fluoro-D-glucose positron emission tomography with computed tomography (FDG-PET/CT) as part of the diagnostic investigation. METHOD: The records of all patients referred to FDG-PET/CT from Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup with the suspicion of PMR and/or GCA during a two-year period, were retrospectively reviewed...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38446427/navigating-the-diagnostic-challenges-of-giant-cell-arteritis-in-a-general-rheumatology-practice-time-for-a-change
#25
JOURNAL ARTICLE
Ivana Ilic, Ioannis Koulas, Lara El Khoury
No abstract text is available yet for this article.
March 5, 2024: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://read.qxmd.com/read/38442463/imaging-to-predict-early-relapses-after-treatment-discontinuation-in-patients-with-large-vessel-giant-cell-arteritis-a-cohort-study
#26
JOURNAL ARTICLE
Andrea K Hemmig, Christof Rottenburger, Luan Baruti, Noemi Mensch, Markus Aschwanden, Diego Kyburz, Maurice Pradella, Daniel Staub, Mihaela Stegert, Christoph T Berger, Stephan Imfeld, Gregor Sommer, Thomas Daikeler
OBJECTIVES: To investigate the value of [18 F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and magnetic resonance imaging (MRI) in predicting relapse after treatment discontinuation in patients with large-vessel giant cell arteritis (LV-GCA). METHODS: This study included patients with LV-GCA whose treatment was discontinued between 2018 and 2023. All patients underwent PET/CT and/or MRI at the time of treatment discontinuation in clinical remission...
February 28, 2024: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/38436149/tomographic-ultrasound-for-three-dimensional-visualization-of-temporal-arteries
#27
JOURNAL ARTICLE
M Naumovska, U Dahlstrand, L Engqvist, M Cinthio, J Albinsson, R Sheikh, A Merdasa, M Malmsjo
OBJECTIVE: Conventional two-dimensional ultrasound has been assessed for the non-invasive diagnosis of giant cell arteritis (GCA), but the results are operator dependent, resulting in low sensitivity. Tomographic three-dimensional (3D) ultrasound is a novel technique that enables the objective documentation of vessel geometry. Here, for the first time, its utility is assessed for visualizing temporal arteries. METHOD: The temporal artery of 14 healthy subjects and three subjects with suspected GCA was examined using tomographic 3D ultrasound...
March 4, 2024: Scandinavian Journal of Rheumatology
https://read.qxmd.com/read/38428963/orbital-and-optic-nerve-sheath-involvement-and-pupil-involving-cranial-nerve-3-palsy-in-giant-cell-arteritis
#28
JOURNAL ARTICLE
Salma A Dawoud, Noor-Us-Sabah Ahmad, Erin M Shriver, Sophia M Chung
Giant cell arteritis (GCA) can present with atypical presentations that are diagnostically challenging. An 84-year-old woman with a history of breast adenocarcinoma treated with lumpectomy and radiation 2 years prior presented with a seizure-like episode.
March 1, 2024: Journal of Rheumatology
https://read.qxmd.com/read/38428111/mir-146a-and-mir-146b-regulate-the-expression-of-icam-1-in-giant-cell-arteritis
#29
JOURNAL ARTICLE
Martina Bonacini, Alessandro Rossi, Ilaria Ferrigno, Francesco Muratore, Luigi Boiardi, Alberto Cavazza, Alessandra Bisagni, Luca Cimino, Luca De Simone, Angelo Ghidini, Giuseppe Malchiodi, Marc Corbera-Bellalta, Maria Cinta Cid, Alessandro Zerbini, Carlo Salvarani, Stefania Croci
Giant cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries. MiRNAs are small, non-coding RNAs that inhibit gene expression at post-transcriptional level. Several miRNAs have been shown to be dysregulated in temporal artery biopsies (TABs) from GCA patients, but their role is unknown. The aims of the present work were: to gain insight into the link between inflammation and miRNA up-regulation in GCA; to identify the role of miR-146a and miR-146b. Primary cultures from TABs were treated with IL-1β, IL-6, soluble IL-6R (sIL6R), IL-17, IL-22, IFNγ, LPS and PolyIC...
February 29, 2024: Journal of Autoimmunity
https://read.qxmd.com/read/38425727/south-african-flag-sign-to-a-giant-coronary-artery-aneurysm
#30
Rakavi Rathinasamy, Nirmal Ghati, Neeraj Parakh, Sanjeev Kumar, Akshay Kumar Bisoi, Sudheer Arava, Rajiv Narang, Balram Bhargava
BACKGROUND: Coronary arteritis leading to aneurysm is one of the unusual presentations of IgG4-related disease. Acute myocardial infarction as a complication of IgG4-related giant coronary artery aneurysm is even rarer. CASE SUMMARY: We describe the case of a 56-year-old gentleman who presented to our institute with Canadian Cardiovascular Society (CCS) class III angina. His symptoms were persistent even with high-dose antianginal medications. He had an acute coronary syndrome two weeks back for which he was treated conservatively in a peripheral health centre...
February 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38418203/referral-of-patients-with-suspected-polymyalgia-rheumatica-how-complete-is-our-view-of-planet-pmr
#31
EDITORIAL
Dario Camellino, Eric L Matteson
No abstract text is available yet for this article.
February 28, 2024: Annals of the Rheumatic Diseases
https://read.qxmd.com/read/38396307/surgical-and-endovascular-cerebral-revascularization-for-cerebral-vasculitis-with-inflammatory-vessel-stenosis-a-case-series
#32
JOURNAL ARTICLE
Simon Schieferdecker, Julian Caspers, Weiss Daniel, Jan Frederick Cornelius, Sajjad Muhammad
Autoimmune vasculitides affect the cerebral vasculature significantly in a considerable number of cases. When immunosuppressive treatments fail to prevent stenosis in cerebral vessels, treatment options for affected patients become limited. In this case series, we present four cases of pharmacoresistant vasculitis with recurrent transient ischemic attacks (TIAs) or stroke successfully treated with either extracranial-intracranial (EC-IC) bypass surgery or endovascular stenting. Both rescue treatments were effective and safe in the selected cases...
February 23, 2024: Acta Neurochirurgica
https://read.qxmd.com/read/38395494/effect-of-combined-treatment-with-prednisone-and-methotrexate-versus-prednisone-alone-over-laboratory-parameters-in-giant-cell-arteritis
#33
RANDOMIZED CONTROLLED TRIAL
Ines Perez-Sancristobal, Paula Alvarez-Hernandez, Cristina Lajas-Petisco, Benjamin Fernandez-Gutierrez
OBJECTIVE: To compare the effect of combined treatment with prednisone and methotrexate (MTX) versus prednisone alone over laboratory parameters in giant cell arteritis (GCA). PATIENTS AND METHODS: We performed a double-blind, placebo-controlled, randomized clinical trial about usefulness of treatment with prednisone and MTX versus prednisone and placebo in GCA (Ann Intern Med 2001;134:106-114). As a part of follow-up of patients (n=42), we performed laboratory analysis in 20 time points during the two-year period of follow-up...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38395453/new-blood-biomarkers-and-imaging-for-disease-stratification-and-monitoring-of-giant-cell-arteritis
#34
JOURNAL ARTICLE
Alessandro Tomelleri, Christian Dejaco
Relapses and late complications remain a concern in giant cell arteritis (GCA). Monitoring strategies are required to effectively tailor treatment and improve patients' outcomes. Current monitoring of GCA is based on clinical assessment and evaluation of traditional inflammatory markers such as C reactive protein and erythrocyte sedimentation rate; however, this approach has limited value in patients receiving interleukin (IL)-6 blocking agents. New blood biomarkers that are less dependent on the IL-6 axis such as IL-23, B cell activating factor, osteopontin and calprotectin have been explored, but none of them has yet accumulated sufficient evidence to qualify as a routine follow-up parameter...
February 23, 2024: RMD Open
https://read.qxmd.com/read/38391344/giant-cell-arteritis-causing-mesenteric-ischemia-without-cranial-manifestations-report-of-an-unusual-case
#35
JOURNAL ARTICLE
Pritika Kushwaha, Meeta Singh, Priyanka Bellichuki, Rajdeep Singh
Giant cell arteritis is a medium to large vessel vasculitis involving most commonly temporal arteries, vertebral and ophthalmic arteries. Giant cell arteritis causing mesenteric ischemia is not so frequent, more so if it occurs without cranial manifestations. Here we present an unusual case of a 26-year-old male patient presenting with subacute intestinal obstruction due to giant cell arteritis leading to mesenteric ischemia.
July 6, 2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38384323/anxiety-and-depression-in-patients-with-giant-cell-arteritis
#36
JOURNAL ARTICLE
Joana Martins-Martinho, André Ponte, Eduardo Dourado, Nikita Khmelinskii, Sofia C Barreira, Ana R Cruz-Machado, Carla Macieira, Vítor Teixeira, Ana M Rodrigues, Diogo Telles-Correia, João E Fonseca, Cristina Ponte
OBJECTIVES: To compare the prevalence of anxiety and depression in patients with GCA with that in the general population, using the Hospital Anxiety and Depression Scale (HADS), and to identify independent predictors of these psychiatric manifestations in patients with GCA. METHODS: We conducted a cross-sectional study including all patients diagnosed with GCA followed during 1 year in a vasculitis outpatient clinic. The HADS and 36-item Short Form (SF-36) questionnaires were prospectively collected...
2024: Rheumatology Advances in Practice
https://read.qxmd.com/read/38375531/characterising-polymyalgia-rheumatica-on-whole-body-18-f-fdg-pet-ct-an-atlas
#37
REVIEW
Claire E Owen, Aurora M T Poon, Bonnia Liu, David F L Liew, Lee Pheng Yap, Victor Yang, Jessica L Leung, Christopher R McMaster, Andrew M Scott, Russell R C Buchanan
The impact of modern imaging in uncovering the underlying pathology of PMR cannot be understated. Long dismissed as an inflammatory syndrome with links to the large vessel vasculitis giant cell arteritis (GCA), a pathognomonic pattern of musculotendinous inflammation is now attributed to PMR and may be used to confirm its diagnosis. Among the available modalities, 18 F-fluorodeoxyglucose (18 F-FDG) PET/CT is increasingly recognized for its high sensitivity and specificity, as well as added ability to detect concomitant large vessel GCA and exclude other relevant differentials like infection and malignancy...
2024: Rheumatology Advances in Practice
https://read.qxmd.com/read/38368558/varicella-zoster-virus-mimicking-giant-cell-arteritis
#38
JOURNAL ARTICLE
Joana Martins-Martinho, Inês Pintado Maury, Inês Leal, Cristina Ponte
No abstract text is available yet for this article.
January 14, 2024: ARP Rheumatol
https://read.qxmd.com/read/38366635/follow-up-ultrasound-examination-in-patients-with-newly-diagnosed-giant-cell-arteritis
#39
JOURNAL ARTICLE
Valentin S Schäfer, Christian Dejaco, Pantelis Karakostas, Charlotte Behning, Peter Brossart, Lara C Burg
OBJECTIVES: Ultrasound is a standard tool to diagnose giant cell arteritis (GCA). Until now, only few studies investigated the role of ultrasound in the follow-up of GCA. The aim of this study was to assess the changes in the intima media thickness (IMT), total number of affected arteries and provisional OMERACT GCA ultrasonography score (OGUS) in a 12-months follow-up period. METHODS: Patients with newly diagnosed GCA were prospectively enrolled. Ultrasound examinations of facial, temporal, carotid, vertebral and axillary arteries were performed at baseline, after three, six, nine and 12 months...
February 15, 2024: Rheumatology
https://read.qxmd.com/read/38359942/paget-disease-as-a-rare-mimicker-of-giant-cell-arteritis
#40
JOURNAL ARTICLE
Madalyn Walsh, Jennifer Strouse, Brittany Bettendorf
Paget disease (PD) is a skeletal disorder that is characterized by excessive osteoclast activity and subsequent increased osteoblast activity that leads to disorganized bone formation. Here, we report a case of a patient whose symptoms initially raised concern for giant cell arteritis (GCA), but further clinical examination ultimately led to an alternative diagnosis.
February 15, 2024: Journal of Rheumatology
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