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Giant cell arteritis

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https://www.readbyqxmd.com/read/29024993/ultrasonographic-findings-as-diagnostic-and-follow-up-tool-in-cranial-giant-cell-arteritis
#1
Yoshinori Taniguchi, Hirofumi Nishikawa, Eri Amano, Shimpei Fujimoto, Yoshio Terada
No abstract text is available yet for this article.
August 28, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29024675/tempo-ral-was-the-heart-of-the-matter
#2
Francesco Pellegrini, Daniele Cirone, Piernicola Machin, Rod Foroozan
A 71-year-old woman was admitted with fever, headache and weight loss associated with elevated inflammatory markers. She developed acute bilateral ophthalmoplegia and asymmetrical ptosis rapidly followed by anterior ischemic optic neuropathy. Although the first temporal artery biopsy (TAB) was negative, contralateral TAB revealed features consistent with giant cell arteritis. Even while under steroid therapy, the patient died a few days later from myocardial infarction. Acute bilateral complete ophthalmoplegia is a rare presentation of a limited number of possible diseases...
October 9, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29020715/diagnosis-and-management-of-polymyalgia-rheumatica
#3
Olwyn Jones, Fraser Birrell
Polymyalgia rheumatica (PMR) is a common inflammatory condition of unknown aetiology with a prevalence of 1 in 133 in the over 50s, and a female to male ratio of 2:1. Symptoms develop over a matter of weeks; typically bilateral shoulder or pelvic girdle pain and stiffness, that is worse in the mornings. Associated symptoms include low-grade fever, malaise, fatigue, low mood, poor appetite, and weight loss. There is no specific diagnostic test for PMR but the usual pattern is a commensurate rise in CRP and ESR...
December 2016: Practitioner
https://www.readbyqxmd.com/read/29020600/trial-of-tocilizumab-in-giant-cell-arteritis
#4
LETTER
John H Stone, Micki Klearman, Neil Collinson
New England Journal of Medicine, Volume 377, Issue 15, Page 1493-1495, October 2017.
October 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29020599/trial-of-tocilizumab-in-giant-cell-arteritis
#5
LETTER
(no author information available yet)
No abstract text is available yet for this article.
October 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29016409/anterior-ischemic-optic-neuropathy-due-to-calciphylaxis
#6
Magne S Sivertsen, Erik H Strøm, Kim M A Endre
A 72-year-old woman experienced anterior ischemic optic neuropathy in her left eye. The funduscopic and fluorescein angiographic findings were strongly suggestive of giant cell arteritis. Temporal artery biopsy revealed extensive calcification in the vessel wall consistent with calciphylaxis. This unusual disorder should be considered in the differential diagnosis of anterior ischemic optic neuropathy, particularly the arteritic form.
October 6, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28994265/recognition-of-giant-cell-arteritis-in-patients-with-polymyalgia-rheumatica-who-have-a-stroke-a-cautionary-tale
#7
Donald H Gutteridge, Frank L Mastaglia
An 82-year-old woman with polymyalgia rheumatica (PMR) on prednisone 7 mg daily was admitted to an acute stroke unit with a right homonymous hemianopia, a left posterior cerebral artery occlusion and occipital lobe infarct. She had raised inflammatory markers, did not have a temporal artery biopsy, and was discharged on the same dose of prednisone. After 21 months, off prednisone, her ophthalmologist, concerned about giant cell arteritis (GCA), restarted prednisone 40 mg daily, with rapid, profound visual improvement...
October 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28993535/teaching-neuroimages-giant-cell-arteritis-presenting-with-acute-ischemic-strokes-due-to-diffuse-intracranial-stenoses
#8
Odysseas Kargiotis, Apostolos Safouris, Vasileios N Petrou, Georgios Magoufis, Eleftherios Stamboulis, Georgios Tsivgoulis
No abstract text is available yet for this article.
October 10, 2017: Neurology
https://www.readbyqxmd.com/read/28987704/the-role-of-colour-doppler-ultrasonography-of-facial-and-occipital-arteries-in-patients-with-giant-cell-arteritis-a-prospective-study
#9
Rok Ješe, Žiga Rotar, Matija Tomšič, Alojzija Hočevar
OBJECTIVE: Colour Doppler Sonography (CDS) in giant cell arteritis (GCA) allows the study of involvement of cranial arteries other than the temporal arteries, which are inconvenient to biopsy, such as the facial (FaA), and occipital (OcA) arteries. We aimed to estimate the frequency of the FaA, and OcA involvement in GCA; and to explore the clinical characteristics of these subgroups of patients. METHODS: From 1 January 2014 to 31 December 2016 we prospectively performed a CDS of the FaA, and OcA in addition to the temporal (TA), and the extracranial supra-aortic arteries in all newly diagnosed patients suspected of having GCA...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28975885/pet-ct-findings-in-patients-with-polymyalgia-rheumatica-without-symptoms-of-cranial-ischaemia
#10
Alexander Lund-Petersen, Anne Voss, Helle Laustrup
INTRODUCTION: Polymyalgia rheumatica (PMR) is an inflammatory disorder that affects the elderly. At present, evidence is limited regarding the usefulness of positron emission tomography-computed tomography (PET-CT) in the diagnosis of PMR. This study aimed to compare patient characteristics and symptoms with PET-CT findings in a Danish population of PMR patients without clinical symptoms of giant cell arteritis. METHODS: The medical records of 50 Danish PET-CT-scanned patients with PMR were reviewed...
October 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28973818/incremental-costs-in-giant-cell-arteritis
#11
Michael Mounié, Nadège Costa, Laurent Sailler, Maryse Lapeyre-Mestre, Robert Bourrel, Nicolas Savy, Laurent Molinier, Grégory Pugnet
OBJECTIVES: To assess and compare direct costs between giant cell arteritis (GCA) patients and matched-controls and identify incremental cost drivers. METHODS: We carried out a population-based, retrospective, cohort study using the French National Health Insurance System Database. Cost analysis was performed from the French health insurance perspective and took into account direct medical and non-medical costs (€, 2014). Costs were evaluated according to different cost components and divided into periods of 6 months for the accurate assessment of care consumption...
October 3, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28968895/discrepancies-between-vascular-and-systemic-inflammation-in-large-vessel-vasculitis-an-important-problem-revisited
#12
Gokhan Keser, Kenan Aksu, Haner Direskeneli
A lack of absolute correlation between systemic inflammation parameters and ongoing vascular disease activity is an important problem in some patients with large vessel vasculitis, especially Takayasu arteritis (TAK). Systemic and vascular wall inflammation in TAK are obviously interrelated, but sometimes they may act independently. There are clear discrepancies between these two types of inflammation, including cytokine patterns and responses to treatment. Vascular and systemic inflammation may also be discordant in two subgroups of giant cell arteritis...
September 7, 2017: Rheumatology
https://www.readbyqxmd.com/read/28968856/interleukin-6-flags-infection-in-tocilizumab-treated-giant-cell-arteritis
#13
Christoph T Berger, Mike Recher, Thomas Daikeler
No abstract text is available yet for this article.
September 8, 2017: Rheumatology
https://www.readbyqxmd.com/read/28968695/increased-expression-of-interleukin-22-in-patients-with-giant-cell-arteritis
#14
Alessandro Zerbini, Francesco Muratore, Luigi Boiardi, Francesco Ciccia, Martina Bonacini, Lucia Belloni, Alberto Cavazza, Luca Cimino, Antonio Moramarco, Riccardo Alessandro, Aroldo Rizzo, Maria Parmeggiani, Carlo Salvarani, Stefania Croci
Objectives: GCA is characterized by arterial remodelling driven by inflammation. IL-22 is an attractive cytokine which acts at the crosstalk between immune and stromal cells. We hypothesized that IL-22 might be induced in GCA and might be involved in disease pathogenesis. Methods: Patients subjected to temporal artery biopsies (TABs) naïve from therapy were enrolled: 27 biopsy-proven GCA, 8 biopsy-negative GCA, 21 biopsy-negative non-GCA patients. Expression of IL-22 was determined in TABs by immunohystochemistry, in plasma by ELISA, in peripheral blood mononuclear cells by real-time PCR and flow cytometry...
September 7, 2017: Rheumatology
https://www.readbyqxmd.com/read/28957963/an-update-on-the-role-of-epigenetics-in-systemic-vasculitis
#15
Patrick Coit, Haner Direskeneli, Amr H Sawalha
PURPOSE OF REVIEW: The purpose of this review is to discuss recent observations of epigenetic changes related to the complex pathogenesis of systemic vasculitides and their contribution to the field. RECENT FINDINGS: There have been new observations of epigenetic changes in vasculitis and their potential role in disease pathogenesis in antineutrophil cytoplasmic antibody-associated vasculitis, giant-cell arteritis, Kawasaki disease, Behçet's disease, and IgA vasculitis...
September 27, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28953579/fluorine-18-fluoro-2-deoxyglucose-positron-emission-tomography-uptake-in-the-superficial-temporal-and-vertebral-arteries-in-biopsy-positive-giant-cell-arteritis
#16
Anthony Michael Sammel, Edward Hsiao, Leslie Schrieber, Beatrice Janssen, Peter Youssef, Clare L Fraser, Chih-Hung Kuo, Hamish Dunn, Dale L Bailey, Paul Roach, Geoffrey Schembri, Elizabeth Bailey, Katherine Nguyen, Peter Farmakis, Rodger Laurent
No abstract text is available yet for this article.
September 26, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28937523/cytomegalovirus-retinitis-associated-with-occlusive-vasculopathy-in-an-elderly-human-immunodeficiency-virus-negative-man
#17
Kareem Moussa, Thuy Doan, Jay M Stewart, Jessica Shantha, John Gonzales, Nisha Acharya, Emmett T Cunningham
PURPOSE: To present a case of cytomegalovirus (CMV) retinitis associated with occlusive vasculopathy presenting as sudden unilateral loss of vision in a human immunodeficiency virus-negative elderly man. METHODS: Clinical case report and literature review. RESULTS: An 84-year-old Chinese man with diabetes mellitus and primary open-angle glaucoma was seen in consultation by our uveitis service for evaluation of sudden vision loss in the right eye...
September 20, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28922343/tocilizumab-actemra-for-giant-cell-arteritis
#18
(no author information available yet)
No abstract text is available yet for this article.
September 25, 2017: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/28916549/positron-emission-tomography-computerized-tomography-in-newly-diagnosed-patients-with-giant-cell-arteritis-who-are-taking-glucocorticoids
#19
Alison H Clifford, Elana M Murphy, Steven C Burrell, Mathew P Bligh, Ryan F MacDougall, J Godfrey Heathcote, Mathieu C Castonguay, Min S Lee, Kara Matheson, John G Hanly
OBJECTIVE: Large vessel uptake on positron emission tomography/computerized tomography (PET/CT) supports the diagnosis of giant cell arteritis (GCA). Its value, however, in patients without arteritis on temporal artery biopsy and in those receiving glucocorticoids remains unknown. We compared PET/CT results in GCA patients with positive (TAB+) and negative temporal artery biopsies (TAB-), and controls. METHODS: Patients with new clinically diagnosed GCA starting treatment with glucocorticoids underwent temporal artery biopsy and PET/CT...
September 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28914854/-giant-cell-arteritis-genetic-and-epigenetic-aspects
#20
S V Guliaev, L A Strizhakov, P I Novikov, N A Mukhin, V V Fomin
The paper describes clinical cases in 2 patients (brothers) with giant cell arteritis. It analyzes the genetic and epigenetic aspects of the disease. The data available in the Russian and foreign literature are given.
2017: Terapevticheskiĭ Arkhiv
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