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M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray
Oral cancer is one of the most prevalent form of cancer and its severity is aggrandized specially among the socio-economically backward population in developing countries. A major fraction of patient population is unable to avail diagnosis for oral cancer due to scarcity of state-of-the-art infrastructure and experienced oral and maxillofacial pathologist. Contemporary gold standard of oral cancer confirmation relies on biopsy report. But biopsy is invasive and thus patients are usually reluctant to undergo this test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, S Patsa, A Dasgupta, N Anjum, M Chakraborty, S Mukhopadhyay, J G Ray
Oral cancer is one of the most prevalent form of cancer and its severity is aggrandized specially among the socio-economically backward population in developing countries. A major fraction of patient population is unable to avail diagnosis for oral cancer due to scarcity of state-of-the-art infrastructure and experienced oral and maxillofacial pathologist. Contemporary gold standard of oral cancer confirmation relies on biopsy report. But biopsy is invasive and thus patients are usually reluctant to undergo this test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Dipanker Singh Mankotia, Guru Dutta Satyarthee, Bhoopendra Singh, Bhawani Shankar Sharma
Association of Dandy-Walker syndrome with occipital meningocele (OMC) is extremely rare and about thirty cases are reported till date in the Western literature. However, OMC is classified by Talamonti et al. into small, large, and giant categories with respective diameters were upto 5 cm in small, large with 5-9 cm, and giant with >9 cm. Usually the size of OMC progressively increases as raised intracranial pressure leads to compensatory cerebrospinal fluid escape into sac with the growth of children. Authors report an interesting case of an 18-month-old female child with extra-gigantic OMC, whose size was almost same since birth, representing the first case of its kind, who underwent successful surgical repair...
October 2016: Journal of Pediatric Neurosciences
Tobias T Tauböck, Thomas Attin
Bulk-fill resin composites represent an innovative class of dental composite materials, developed to simplify and expedite the restoration process. They can be adequately photopolymerized up to 4–5mm composite thickness and therefore permit a more economical restorative approach as compared to conventional resin composites. The current paper summarizes the most important facts on bulk-fill composite materials and provides recommendations for the successful use of these materials in daily practice based on upto-date in vitro and in vivo research...
2016: Swiss Dental Journal
Abhishek Purkayastha, Neelam Sharma, Abhishek Pathak, Bhupendra Nath Kapur, Vibha Dutta
Retinoblastoma (Rb) is a common childhood malignancy but bilateral Rb with metastasis to parotids is very uncommon. To the best of our knowledge, bilateral Rb metastasizing to parotids is very rare and this is the fifth such case reported in world literature till date in a 2-year-old male child who underwent exenteration of left eye for bilateral Rb and later developed recurrent metastasis to left parotid requiring parotidectomy. A year later he presented again with swelling left parotid region extending from occipital region reaching upto left anterior chest wall with intra-cranial extension on magnetic resonance imaging...
April 2016: Translational Pediatrics
S A Khan, N Muhammad, M A Khan, A Kamal, Z U Rehman, S Khan
Bardet-Biedl syndrome (BBS) is an autosomal recessive multisystemic human genetic disorder characterized by six major defects including obesity, mental retardation, renal anomalies, polydactyly, retinal degeneration and hypogenitalism. In several cases of BBS, few other features such as metabolic defects, cardiovascular anomalies, speech deficits, hearing loss, hypertension, hepatic defects and high incidence of diabetes mellitus have been reported as well. The BBS displays extensive genetic heterogeneity. To date, 19 genes have been mapped on different chromosomes causing BBS phenotypes having varied mutational load of each BBS gene...
July 2016: Clinical Genetics
V Sreelakshmi, Annie Abraham
ETHNOPHARMACOLOGICAL RELEVANCE: Cataract is the clouding or opacity that develops in the eye's lens and is considered to be an unavoidable consequence of aging due to irreversible lens damage. Free radicals and oxidant species are reported to be the major factor responsible for the onset and pathology of cataract. No pharmacological measures are formulated to treat cataract blindness and surgical removal of the opaque lens is the only remedy till date. Boosting of antioxidant potential of the lens is proved to prevent cataract and many indigenous plants have been screened for anticataractogenic potential in the last decades...
February 3, 2016: Journal of Ethnopharmacology
Amit Kumar Sinha, Hamada AbdElgawad, Gaurav Zinta, Antony Franklin Dasan, Rindra Rasoloniriana, Han Asard, Ronny Blust, Gudrun De Boeck
Salinity fluctuation is one of the main factors affecting the overall fitness of marine fish. In addition, water borne ammonia may occur simultaneously with salinity stress. Additionally, under such stressful circumstances, fish may encounter food deprivation. The physiological and ion-osmo regulatory adaptive capacities to cope with all these stressors alone or in combination are extensively addressed in fish. To date, studies revealing the modulation of antioxidant potential as compensatory response to multiple stressors are rather lacking...
2015: PloS One
N R Shapla, M A Islam, S M Shahida, Z Parveen, Y S Lipe
This observational study was carried out to identify the various types of high risk pregnancy and to determine the maternal and foetal outcome. The study was carried out on 206 pregnant high risk women in the Gynecology and Obstetrics department of Border Guard Hospital, Dhaka from January 2012 to December 2012. During mentioned period among 598 pregnant women 206 high risk pregnancy cases were randomly selected. Pregnant women (gestational age from 34 weeks upto 40 weeks) having medical condition and pregnancy related high risk factors were included and uncomplicated pregnancy, pregnancy before 37 weeks, post dated pregnancy were excluded from this study...
April 2015: Mymensingh Medical Journal: MMJ
Damini Singh, Divya Goel, Rakesh Bhatnagar
Brucella abortus is the etiologic agent of Brucellosis, a zoonotic infection affecting a wide range of animals. It is a highly infectious disease of pandemic potential reporting over 500,000 new human cases annually. Till date, there is no reported vaccine for humans and the available animal vaccines are unsafe, therefore a safe and effective subunit vaccine is highly sought for. In this study, we have evaluated rL7/L12 protein encapsulated in microparticles of PLGA (85:15), a biocompatible and biodegradable polymer approved by FDA for human use...
June 4, 2015: Vaccine
M A Haque, M Khalil, S Z Sultana, S Mannan, M M Uddin, M Hossain, A Ara, S Choudhury, N J Shammi
This cross sectional descriptive study was done by using nonprobability sampling technique and performed by examining 63 (sixty three) cerebellum. Out of them 40 postmortem human cerebellum collected from Bangladeshi cadavers of both sexes (male 25 and female 15) age ranging from 5 to 60 years and 23 cerebellums from caesarian section of intrauterine death cases of both sexes (male 14 and female 9) age ranging from 34 to 41 weeks of gestation. Specimens were collected from dead bodies autopsied on different dates from April' 2009 to September' 2009 at the autopsy laboratory of department of Forensic Medicine and prenatal cases from Gynaecology and Obstetrics Department of Mymensingh Medical College, Mymensingh...
January 2015: Mymensingh Medical Journal: MMJ
Michael Darmon, Sandra Malak, Isabelle Guichard, Benoit Schlemmer
Tumor lysis syndrome is characterized by the massive destruction of malignant cells and the release in the extra-cellular space of their content. While Tumor lysis syndrome may occur spontaneously before treatment, it usually develops shortly after the initiation of cytotoxic chemotherapy. These metabolites can overwhelm the homeostatic mechanisms with development of hyperuricaemia, hyperkalaemia, hyperphosphataemia, and hypocalcaemia. These biological manifestations may lead to clinical manifestations including, acute kidney injury, seizure, or sudden death that require intensive care...
September 2008: Revista Brasileira de Terapia Intensiva
Aarti Nagayach, Nisha Patro, Ishan Patro
Diabetes Mellitus is associated with increased risk of cognitive and behavioural disorders with hitherto undeciphered role of glia. Glia as majority population in brain serve several vital functions, thus require pertinent revelation to further explicate the mechanisms affecting the brain function following diabetes. In this study we have evaluated glial changes in terms of phenotypic switching, proliferation and expression of activation cell surface markers and associated cellular degeneration in hippocampus following STZ-induced diabetes and caused cognitive impairments...
September 2014: Metabolic Brain Disease
M Iwasaki
According to the ministry of Health, Labour and welfare of Japan, Cancer has been the leading cause of death in Japan since 1981. ([1]) As per the data in 2010, in Japan, one in every three deaths was due to cancer. ([2]) The Japanese Government has introduced so far, three terms of 10 years strategies for Cancer control since 1984 till date. The budget allocated for cancer control in 2009 was 52.5 billion yen in Japan. ([3]) Lung is the leading site for cancer in both males and females in Japan. In males, following the lung, stomach, liver, colon and pancreas are other leading sites while in the females, stomach, colon, pancreas and breast are the other leading sites...
2012: Journal of Stem Cells & Regenerative Medicine
Alok Sen, A Khetarpal
BACKGROUND: Strategic blood reserves are an important component in meeting blood needs and this can be accomplished through the establishment of a frozen blood program. METHODS: One hundred units of packed RBC were glycerolized using the Haemonetics ACP 215 automated cell processor and placed in a -86 °C deep freezer for freezing and storage. Product weight, hematocrit, RBC count, WBC count and hemoglobin were recorded prior to freezing. Twenty five bags were thawed and deglycerolized after every three months starting at one year from the date of first glycerolization In addition to the earlier parameters the bags were assessed for supernatant osmolality, pH, supernatant hemoglobin, ATP levels and supernatant potassium and from these red cell recovery, percentage hemolysis, supernatant glycerol and red cell viability were estimated...
October 2013: Medical Journal, Armed Forces India
S Akhtar, W Bhat, A Magdum, P R W Stanley
INTRODUCTION: Melanoma in situ (MIS) is a non-invasive lesion accounting for up to 27% of all melanomas by Coory et al. (2006).(1) MIS may be a precursor to invasive disease. The Lentigo Maligna (LM) subgroup of MIS carries upto a 4.7% lifetime risk of developing an invasive component by Agarwal-Antal et al. (2002).(2) Surgical excision is recommended however other modalities of treatments are possible. In this study we aim to assess whether histological margins following excision of in situ melanoma has any bearing on recurrence or progression to malignancy...
March 2014: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Sharbati R Singh, Rohtas Singh, Sanjay Kalia, Sunita Dalal, A K Dhawan, Rajwant K Kalia
Bamboos (family Poaceae) are the most beautiful and useful plants on the Earth, mainly found in the tropical and sub-tropical regions of the world. Bamboos are fast growing and early maturing, but lack of proper management of bamboo resources is leading to rapid reduction of the existing bamboosetum. Bamboo propagation through seeds is limited due to long flowering cycle of upto 120 years, seed sterility and short seed viability. Infrequent and unpredictable flowering events coupled with peculiar monocarpic behaviour i...
January 2013: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
Erhan Tatar, Adam Uslu, Ahmet Aykas, Funda Tasli, Ozgur Oztekin, Gulsum Akgun Cagliyan
BACKGROUND: Recurrent episodes of venous thrombosis have been closely correlated with JAK2 V617F mutation. Upto date, JAK2 gene mutation has not been defined as a prothrombic risk factor in renal transplant recipients. Herein; we present a case of portosplenic vein thrombosis in a primary renal transplant recipient with JAK2 V617F mutation who had no history of prior venous thromboembolism or thrombophilia. CASE PRESENTATION: A 59 year old female caucasian patient with primary kidney transplant admitted with vague abdominal pain at left upper quadrant...
2013: BMC Nephrology
Praveen V Date, Mitesh D Patel, Sharmila B Majee, Abdul Samad, Padma V Devarajan
The present study discloses the design of folate anchored Rifampicin-Poly methylvinylether maleic anhydride copolymer (Gantrez AN-119, Gantrez) nanoparticles (RFMGzFa) by ionic complexation. Folic acid was anchored to the preformed drug loaded nanoparticles. Folic acid was anchored in different concentration by simply varying the amount of folic acid added during preparation. RFMGzFa nanoparticles were prepared by emulsion solvent diffusion method. Gantrez AN-119 rapidly hydrolyzes in aqueous medium releasing carboxylic acid groups, to create an acidic environment...
May 2013: Journal of Biomedical Nanotechnology
Berardino De Bari, Filippo Alongi, Pierfrancesco Franco, Patrizia Ciammella, Tarik Chekrine, Lorenzo Livi, Barbara A Jereczek-Fossa, Andrea Riccardo Filippi
PURPOSE: Radiotherapy (RT) has an established role in the treatment of prostate cancer patients. Despite the large number of patients treated with RT, some issues about optimal techniques, doses, volumes, timing, and association with androgen deprivation are still subject of debate. The aim of this survey was to determine the patterns of choice of Italian radiation oncologists in two different clinical cases of prostate cancer patients treated with radical RT. STUDY DESIGN: During the 2010 Italian Association of Radiation Oncology (AIRO) National congress, four different clinical cases were presented to attending radiation oncologists...
October 2013: La Radiologia Medica
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