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Joost R C Lameijer, Angela Coolen, Adri C Voogd, Luc J Strobbe, Marieke W J Louwman, Dick Venderink, Vivian C Tjan-Heijnen, Lucien E M Duijm
PURPOSE: To determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography. METHODS: We included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clinical data were collected for all recalls. Screening outcome was determined for recalled women with or without evaluation of contralateral breast abnormalities. RESULTS: Of 3,995 recalls (recall rate 3...
April 17, 2018: European Radiology
Arianna Ferrari, Luca Bertolaccini, Piergiorgio Solli, Paola Oriana Di Salvia, David Scaradozzi
Lung cancer is the leading cause of cancer death and second most common cancer among both men and women, but most of them are detected when patients become symptomatic and in late-stage. Chest radiography (CR) is a basic technique for the investigation of lung cancer and has the benefit of convenience and low radiation dose, but detection of malignancy is often difficult. The introduction of computed tomography (CT) for screening has increased the proportion of lung cancer detected but with higher exposure dose and higher costs...
March 2018: Annals of Translational Medicine
Mina Yousefi, Adam Krzyżak, Ching Y Suen
Digital breast tomosynthesis (DBT) was developed in the field of breast cancer screening as a new tomographic technique to minimize the limitations of conventional digital mammography breast screening methods. A computer-aided detection (CAD) framework for mass detection in DBT has been developed and is described in this paper. The proposed framework operates on a set of two-dimensional (2D) slices. With plane-to-plane analysis on corresponding 2D slices from each DBT, it automatically learns complex patterns of 2D slices through a deep convolutional neural network (DCNN)...
April 12, 2018: Computers in Biology and Medicine
Hironari Masuda, Shuji Taketomi, Hiroshi Inui, Naoya Shimazaki, Nobuhiro Nishihara, Seikai Toyooka, Hirotaka Kawano, Takumi Nakagawa
PURPOSE: Anterior cruciate ligament (ACL) reconstruction using a bone-patellar tendon-bone (BTB) graft is known to provide secure fixation due to the direct bone-to-bone integration of the bone plug and bone tunnel. It is important to know the time required for bone integration when designing the postoperative rehabilitation protocol or deciding when the patient can return to competition-level activity, especially if the patient is an athlete. However, because reports are scarce, the period necessary for bone-to-bone integration after ACL reconstruction using a BTB graft remains unclear...
April 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Ryoko Ohashi, Michinobu Nagao, Izumi Nakamura, Takahiro Okamoto, Shuji Sakai
BACKGROUND: The aim of this study was to determine if the diagnostic performance of breast lesion examinations could be improved using both digital breast tomosynthesis (DBT) and conventional digital mammography (CDM). METHODS: Our institutional review board approved the protocol, and patients were provided the opportunity to opt out of the study. A total of 628 patients aged 22-91 years with abnormal screening results or clinical symptoms were consecutively enrolled between June 2015 and March 2016...
April 12, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Stephen L Rose, Julie L Shisler
OBJECTIVE: The question of benefits versus harms of breast cancer screening for women younger than 50 years old has been the subject of debate. We investigate if the addition of tomosynthesis to mammography improves screening performance outcomes for women in this age group. MATERIALS AND METHODS: Screening performance for 59,921 patients (41,542 digital mammography and 18,379 tomosynthesis) younger than 50 years old was collected from a community-based screening network from January 1, 2015, to December 31, 2015...
April 9, 2018: AJR. American Journal of Roentgenology
Kimberly M Ray, Jessica H Hayward, Bonnie N Joe
Breast MR imaging has been shown to identify unsuspected sites of cancer in the ipsilateral breast in 16% of women with newly diagnosed breast cancer. Breast MR imaging identifies occult cancer in the contralateral breast in 3% to 5% of women. Early evidence suggests that the added value of MR imaging for staging may be attenuated in women who also undergo tomosynthesis, particularly those with nondense breasts. Breast MR imaging is complementary to ultrasound imaging in evaluating regional nodal basins. Ongoing prospective randomized clinical trials should clarify the impact of preoperative breast MR imaging on clinical outcomes...
May 2018: Magnetic Resonance Imaging Clinics of North America
Anna Vlahiotis, Brian Griffin, A Thomas Stavros, Jay Margolis
Background: Little data exist on real-world patterns and associated costs of downstream breast diagnostic procedures following an abnormal screening mammography or clinical exam. Objectives: To analyze the utilization patterns in real-world clinical settings for breast imaging and diagnostic procedures, including the frequency and volume of patients and procedures, procedure sequencing, and associated health care expenditures. Materials and methods: Using medical claims from 2011 to 2015 MarketScan Commercial and Medicare Databases, adult females with breast imaging/diagnostic procedures (diagnostic mammography, ultrasound, molecular breast imaging, tomosynthesis, magnetic resonance imaging, or biopsy) other than screening mammography were selected...
2018: ClinicoEconomics and Outcomes Research: CEOR
Melissa A Durand
Digital breast tomosynthesis (DBT) has improved conventional mammography by increasing cancer detection while reducing recall rates. However, these benefits come at the cost of increased radiation dose. Synthesized mammography (s2D) has been developed to provide the advantages of DBT with nearly half the radiation dose. Since its F.D.A. approval, multiple studies have evaluated the clinical performance of s2D. In clinical practice, s2D images are not identical to conventional 2D images and are designed for interpretation with DBT as a complement...
April 4, 2018: Diagnostics
Ravi K Samala, Heang-Ping Chan, Lubomir M Hadjiiski, Mark A Helvie, Caleb Richter, Kenny Cha
Deep learning models are highly parameterized, resulting in difficulty in inference and transfer learning for image recognition tasks. In this work, we propose a layered pathway evolution method to compress a deep convolutional neural network (DCNN) for classification of masses in digital breast tomosynthesis (DBT). The objective is to prune the number of tunable parameters while preserving the classification accuracy. In the first stage transfer learning, 19,632 augmented regions-of-interest (ROIs) from 2,454 mass lesions on mammograms were used to train a pre-trained DCNN on ImageNet...
April 4, 2018: Physics in Medicine and Biology
Xuan-Anh Phi, Alberto Tagliafico, Nehmat Houssami, Marcel J W Greuter, Geertruida H de Bock
BACKGROUND: This study aimed to systematically review and to meta-analyse the accuracy of digital breast tomosynthesis (DBT) versus digital mammography (DM) in women with mammographically dense breasts in screening and diagnosis. METHODS: Two independent reviewers identified screening or diagnostic studies reporting at least one of four outcomes (cancer detection rate-CDR, recall rate, sensitivity and specificity) for DBT and DM in women with mammographically dense breasts...
April 3, 2018: BMC Cancer
Carin Meltzer, Jenny Vikgren, Bengt Bergman, David Molnar, Rauni Rossi Norrlund, Asmaa Hassoun, Bengt Gottfridsson, Magnus Båth, Åse A Johnsson
Purpose To investigate the performance of digital tomosynthesis (DTS) for detection and characterization of incidental solid lung nodules. Materials and Methods This prospective study was based on a population study with 1111 randomly selected participants (age range, 50-64 years) who underwent a medical evaluation that included chest computed tomography (CT). Among these, 125 participants with incidental nodules 5 mm or larger were included in this study, which added DTS in conjunction with the follow-up CT and was performed between March 2012 and October 2014...
April 3, 2018: Radiology
Kyung Soo Lee, Myung Jin Chung
No abstract text is available yet for this article.
April 3, 2018: Radiology
Muhammad U Ghani, Molly D Wong, Farid H Omoumi, Bin Zheng, Laurie L Fajardo, Aimin Yan, Xizeng Wu, Hong Liu
This study compared the detectability of simulated tumors using a high-energy X-ray inline phase sensitive digital breast tomosynthesis (DBT) prototype and a commercial attenuation-based DBT system. Each system imaged a 5-cm thick modular breast phantom with 50-50 adipose-glandular percentage density containing contrast-detail (CD) test objects to simulate different tumor sizes. A commercial DBT system acquired 15 projection views over 15 degrees (15d-15p) was used to acquire the attenuation-based projection views and to reconstruct the conventional DBT slices...
March 2018: Physica Medica: PM
Taghreed I Alshafeiy, Jonathon V Nguyen, Carrie M Rochman, Brandi T Nicholson, James T Patrie, Jennifer A Harvey
Purpose To compare the outcome of architectural distortion (AD) without associated mass only on digital breast tomosynthesis (DBT) with AD seen at two-dimensional (2D) mammography and to evaluate if the incidence of malignancy is influenced by the presence of a correlate at ultrasonography (US). Materials and Methods This retrospective study had institutional review board approval and was HIPAA compliant. All consecutive cases in which patients with AD were ultimately assigned Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 categories from 2009 to 2016 were reviewed by three readers for visibility (2D vs DBT)...
March 27, 2018: Radiology
Gilda Boroumand, Ida Teberian, Laurence Parker, Vijay M Rao, David C Levin
OBJECTIVE: There have been many recent developments in breast imaging, including the 2009 revision of the U.S. Preventive Services Task Force's breast cancer screening guidelines and the approval of digital breast tomosynthesis (DBT) for clinical use in 2011. The objective of this study is to evaluate screening mammography utilization trends among the Medicare population from 2005 to 2015 and examine the volume of DBT studies performed in 2015, the first year for which procedural billing codes for DBT are available...
March 23, 2018: AJR. American Journal of Roentgenology
Bhavika K Patel, Matthew Covington, Victor J Pizzitola, Roxanne Lorans, Marina Giurescu, William Eversman, John Lewin
OBJECTIVE: As experience and aptitude in digital breast tomosynthesis (DBT) have increased, radiologists are seeing more areas of architectural distortion (AD) on DBT images compared with standard 2D mammograms. The purpose of this study is to report our experience using tomosynthesis-guided vacuum-assisted biopsies (VABs) for ADs that were occult at 2D mammography and ultrasound and to analyze the positive predictive value for malignancy. MATERIALS AND METHODS: We performed a retrospective review of 34 DBT-detected ADs that were occult at mammography and ultrasound...
March 23, 2018: AJR. American Journal of Roentgenology
Masoud Jadidi, Magnus Båth, Sven Nyrén
OBJECTIVE: To compare the quality of images obtained with two different protocols with different acquisition time and the influence from image post processing in a chest digital tomosynthesis (DTS) system. METHODS: 20 patients with suspected lung cancer were imaged with a chest X-ray equipment with tomosynthesis option. Two examination protocols with different acquisition times (6.3 s and 12 s) were performed on each patient. Both protocols were presented with two different image post processing (standard DTS processing and more advanced processing optimised for chest radiography)...
March 22, 2018: British Journal of Radiology
Etta D Pisano
No abstract text is available yet for this article.
April 2018: Radiology
Francesca Caumo, Giovanna Romanucci, Kylie Hunter, Manuel Zorzi, Silvia Brunelli, Petra Macaskill, Nehmat Houssami
BACKGROUND: The Verona population-based breast cancer (BC) screening program provides biennial mammography to women aged 50-69 years. Based on emerging evidence of enhanced detection, the program transitioned to digital breast tomosynthesis (DBT) screening. METHODS: This is a prospective pilot evaluation of DBT with synthesised 2D mammography screening implemented during April 2015-March 2017; the rate and characteristics of cancers detected at DBT screening were compared with those detected at the preceding digital mammography (DM) screening round (April 2013-March 2015) in the same screening program...
March 20, 2018: Breast Cancer Research and Treatment
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