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https://www.readbyqxmd.com/read/27908166/improved-targeting-accuracy-of-lung-tumor-biopsies-with-scanning-beam-digital-x-ray-tomosynthesis-image-guidance
#1
Geoff Nelson, Meng Wu, Cameron Hinkel, Ganesh Krishna, Tobias Funk, Jarrett Rosenberg, Rebecca Fahrig
PURPOSE: Electromagnetic navigation bronchoscopy (ENB) provides improved targeting accuracy during transbronchial biopsies of suspicious nodules. The greatest weakness of ENB-based guidance is the registration divergence that exists between the planning CT, acquired days or weeks before the intervention, and the patient on the table on the day of the intervention. Augmenting ENB guidance with real-time tomosynthesis imaging during the intervention could mitigate the divergence and further improve the yield of ENB-guided transbronchial biopsies...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27908154/mass-detection-in-digital-breast-tomosynthesis-deep-convolutional-neural-network-with-transfer-learning-from-mammography
#2
Ravi K Samala, Heang-Ping Chan, Lubomir Hadjiiski, Mark A Helvie, Jun Wei, Kenny Cha
PURPOSE: Develop a computer-aided detection (CAD) system for masses in digital breast tomosynthesis (DBT) volume using a deep convolutional neural network (DCNN) with transfer learning from mammograms. METHODS: A data set containing 2282 digitized film and digital mammograms and 324 DBT volumes were collected with IRB approval. The mass of interest on the images was marked by an experienced breast radiologist as reference standard. The data set was partitioned into a training set (2282 mammograms with 2461 masses and 230 DBT views with 228 masses) and an independent test set (94 DBT views with 89 masses)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27908152/design-of-a-model-observer-to-evaluate-calcification-detectability-in-breast-tomosynthesis-and-application-to-smoothing-prior-optimization
#3
Koen Michielsen, Johan Nuyts, Lesley Cockmartin, Nicholas Marshall, Hilde Bosmans
PURPOSE: In this work, the authors design and validate a model observer that can detect groups of microcalcifications in a four-alternative forced choice experiment and use it to optimize a smoothing prior for detectability of microcalcifications. METHODS: A channelized Hotelling observer (CHO) with eight Laguerre-Gauss channels was designed to detect groups of five microcalcifications in a background of acrylic spheres by adding the CHO log-likelihood ratios calculated at the expected locations of the five calcifications...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27888024/performance-of-photon-counting-breast-computed-tomography-digital-mammography-and-digital-breast-tomosynthesis-in-evaluating-breast-specimens
#4
Ann-Christin Rößler, Willi Kalender, Daniel Kolditz, Christian Steiding, Veikko Ruth, Caroline Preuss, Sandra Christina Peter, Barbara Brehm, Matthias Hammon, Rüdiger Schulz-Wendtland, Evelyn Wenkel
RATIONALE AND OBJECTIVES: This study compared a novel photon-counting breast computed tomography (pcBCT) system with digital mammography (DM) and digital breast tomosynthesis (DBT) systems. For this reason, surgical specimens were examined with all three techniques and rated by three observers. MATERIALS AND METHODS: A total of 30 surgical specimens were investigated with DM, DBT, and pcBCT; the associated images were shown to three experienced radiologists. Findings (22 microcalcifications and 23 mass lesions) were recorded and compared to the results of the pathological examination...
November 22, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27870337/breast-cancers-found-with-digital-breast-tomosynthesis-a-comparison-of-pathology-and-histologic-grade
#5
Wei-Shin Wang, Lara Hardesty, James Borgstede, Jayme Takahashi, Sharon Sams
To compare the pathology and histologic grading of breast cancers detected with digital breast tomosynthesis to those found with conventional digital mammography. The institutional review board approved this study. A database search for all breast cancers diagnosed from June 2012 through December 2013 was performed. Imaging records for these cancers were reviewed and patients who had screening mammography with tomosynthesis as their initial examination were selected. Five dedicated breast imaging radiologists reviewed each of these screening mammograms to determine whether the cancer was visible on conventional digital mammography or whether tomosynthesis was needed to identify the cancer...
November 2016: Breast Journal
https://www.readbyqxmd.com/read/27861206/comparison-of-the-detection-rate-of-simulated-microcalcifications-in-full-field-digital-mammography-digital-breast-tomosynthesis-and-synthetically-reconstructed-2-dimensional-images-performed-with-2-different-digital-x-ray-mammography-systems
#6
Sabine Peters, Martin Hellmich, Alexander Stork, Jörn Kemper, Olga Grinstein, Michael Püsken, Leandra Stahlhut, Sonja Kinner, David Maintz, Kathrin Barbara Krug
OBJECTIVE: The aim of this study was to compare the microcalcification detectability in an anthropomorphic phantom model regarding number, size, and shape in full-field digital mammography (FFDM), synthetically reconstructed 2-dimensional (Synthetic-2D) images, and digital breast tomosynthesis (DBT) performed with 2 different x-ray mammography systems. MATERIALS AND METHODS: Simulated microcalcifications of different numbers (0 to >39), sizes (diameter, 100-800 μm), and shapes (round vs heterogeneous) were scattered by random distribution on 50 film phantoms each divided in 4 quadrants...
November 17, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27854006/mammography-an-update-of-the-eusobi-recommendations-on-information-for-women
#7
Francesco Sardanelli, Eva M Fallenberg, Paola Clauser, Rubina M Trimboli, Julia Camps-Herrero, Thomas H Helbich, Gabor Forrai
: This article summarises the information to be offered to women about mammography. After a delineation of the aim of early diagnosis of breast cancer, the difference between screening mammography and diagnostic mammography is explained. The need to bring images and reports from the previous mammogram (and from other recent breast imaging examinations) is highlighted. Mammography technique and procedure are described with particular attention to discomfort and pain experienced by a small number of women who undergo the test...
November 16, 2016: Insights Into Imaging
https://www.readbyqxmd.com/read/27842661/diagnostic-performance-of-digital-breast-tomosynthesis-with-a-wide-scan-angle-compared-to-full-field-digital-mammography-for-the-detection-and-characterization-of-microcalcifications
#8
Paola Clauser, Georg Nagl, Thomas H Helbich, Katja Pinker-Domenig, Michael Weber, Panagiotis Kapetas, Maria Bernathova, Pascal A T Baltzer
OBJECTIVES: To assess the diagnostic performance of digital breast tomosynthesis (DBT), with a wide scan-angle, compared to full-field digital mammography (FFDM), for the detection and characterization of microcalcifications. METHODS: IRB approval was obtained for this retrospective study. We selected 150 FFDM and DBT (50 benign and 50 malignant histologically verified microcalcifications, 50 cases classified as BI-RADS 1). Four radiologists evaluated, in separate sessions and blinded to patients' history and histology, the presence of microcalcifications...
December 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27837442/non-calcified-ductal-carcinoma-in-situ-of-the-breast-comparison-of-diagnostic-accuracy-of-digital-breast-tomosynthesis-digital-mammography-and-ultrasonography
#9
Xiaohui Su, Qing Lin, Chunxiao Cui, Wenjian Xu, Zhimin Wei, Jie Fei, Lili Li
BACKGROUND: To retrospectively compare the diagnostic accuracy of digital breast tomosynthesis (DBT), digital mammography (DM), and ultrasonography (US) in non-calcified ductal carcinoma in situ (DCIS, include DCIS with micro-invasion). PATIENTS AND METHODS: Ninety-eight patients with non-calcified DCIS (include DCIS with micro-invasion) were enrolled in our study. Breast carcinoma in situ was confirmed by surgical pathologic evaluation. Our Institutional Review Board granted approval and the participating women provided written informed consent...
November 11, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27814818/digital-breast-tomosynthesis-utilization-in-the-united-states-a-survey-of-physician-members-of-the-society-of-breast-imaging
#10
Lara A Hardesty, Sarah M Kreidler, Deborah H Glueck
PURPOSE: To assess utilization of digital breast tomosynthesis (DBT) and examine criteria for offering DBT to patients. METHODS: We created an online survey for physician members of the Society of Breast Imaging to assess their use of DBT. The questions covered availability of DBT at the participant's practice, whether DBT was used for clinical care or research, clinical decision rules guiding patient selection for DBT, costs associated with DBT, plans to obtain DBT, and breast imaging practice characteristics...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27814817/digital-breast-tomosynthesis-and-the-challenges-of-implementing-an-emerging-breast-cancer-screening-technology-into-clinical-practice
#11
Christoph I Lee, Constance D Lehman
Emerging imaging technologies, including digital breast tomosynthesis, have the potential to transform breast cancer screening. However, the rapid adoption of these new technologies outpaces the evidence of their clinical and cost-effectiveness. The authors describe the forces driving the rapid diffusion of tomosynthesis into clinical practice, comparing it with the rapid diffusion of digital mammography shortly after its introduction. They outline the potential positive and negative effects that adoption can have on imaging workflow and describe the practice management challenges when incorporating tomosynthesis...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27807699/position-paper-on-screening-for-breast-cancer-by-the-european-society-of-breast-imaging-eusobi-and-30-national-breast-radiology-bodies-from-austria-belgium-bosnia-and-herzegovina-bulgaria-croatia-czech-republic-denmark-estonia-finland-france-germany-greece
#12
Francesco Sardanelli, Hildegunn S Aase, Marina Álvarez, Edward Azavedo, Henk J Baarslag, Corinne Balleyguier, Pascal A Baltzer, Vanesa Beslagic, Ulrich Bick, Dragana Bogdanovic-Stojanovic, Ruta Briediene, Boris Brkljacic, Julia Camps Herrero, Catherine Colin, Eleanor Cornford, Jan Danes, Gérard de Geer, Gul Esen, Andrew Evans, Michael H Fuchsjaeger, Fiona J Gilbert, Oswald Graf, Gormlaith Hargaden, Thomas H Helbich, Sylvia H Heywang-Köbrunner, Valentin Ivanov, Ásbjörn Jónsson, Christiane K Kuhl, Eugenia C Lisencu, Elzbieta Luczynska, Ritse M Mann, Jose C Marques, Laura Martincich, Margarete Mortier, Markus Müller-Schimpfle, Katalin Ormandi, Pietro Panizza, Federica Pediconi, Ruud M Pijnappel, Katja Pinker, Tarja Rissanen, Natalia Rotaru, Gianni Saguatti, Tamar Sella, Jana Slobodníková, Maret Talk, Patrice Taourel, Rubina M Trimboli, Ilse Vejborg, Athina Vourtsis, Gabor Forrai
: EUSOBI and 30 national breast radiology bodies support mammography for population-based screening, demonstrated to reduce breast cancer (BC) mortality and treatment impact. According to the International Agency for Research on Cancer, the reduction in mortality is 40 % for women aged 50-69 years taking up the invitation while the probability of false-positive needle biopsy is <1 % per round and overdiagnosis is only 1-10 % for a 20-year screening. Mortality reduction was also observed for the age groups 40-49 years and 70-74 years, although with "limited evidence"...
November 2, 2016: European Radiology
https://www.readbyqxmd.com/read/27807331/-comparison-of-the-diagnostic-efficiency-between-digital-breast-tomosynthesis-and-full-field-digital-mammography
#13
Siqing Cai, Jianxiang Yan, Donglu Cai, Meiling Huang, Lisheng Yan
To explore the effect of digital breast tomosynthesis (DBT) on the classification of breast imaging-reporting and data system (BI-RADS) and its significance.
 Methods: A total of 832 patients with breast diseases, who came from Second Clinical College of Fujian Medical University from May 2013 to November 2013, were collected. The patients were examined by double position radiography (including craniocaudol and mediolateral oblique) and COMBO mode [including DBT and full-field digital mammography (FFDM)]...
October 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27806582/response-to-comment-on-large-area-cmos-active-pixel-sensor-x-ray-imager-for-digital-breast-tomosynthesis-analysis-modeling-and-characterization-%C3%A2-med-phys-43-1578-1579-2016
#14
Chumin Zhao, Anastasios C Konstantinidis, Jerzy Kanicki
No abstract text is available yet for this article.
November 2016: Medical Physics
https://www.readbyqxmd.com/read/27786548/advances-in-digital-breast-tomosynthesis
#15
Regina J Hooley, Melissa A Durand, Liane E Philpotts
OBJECTIVE: Digital breast tomosynthesis (DBT) has rapidly emerged as an important new imaging tool that reduces the masking effect of overlapping fibroglandular tissue, thereby improving breast cancer detection. This article will review key features of DBT including technique, clinical implementation, and benign and malignant imaging findings. We will also present the benefits of DBT in screening, diagnostic workup, and image-guided biopsy. CONCLUSION: Tomosynthesis improves interpretive performance and will likely replace conventional 2D mammography in clinical practice...
October 27, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27782687/assessing-task-performance-in-ffdm-dbt-and-synthetic-mammography-using-uniform-and-anthropomorphic-physical-phantoms
#16
Lynda C Ikejimba, Stephen J Glick, Kingshuk Roy Choudhury, Ehsan Samei, Joseph Y Lo
PURPOSE: The purpose of this study is to quantify the differences in detectability between full field digital mammography (FFDM), digital breast tomosynthesis (DBT), and synthetic mammography (SM) for challenging, low contrast signals, in the context of both a uniform and an anthropomorphic, textured phantom. METHODS: Images of the phantoms were acquired using a Hologic Selenia Dimensions system. Images were taken at 50%, 100%, and 200% of the dose delivered under automatic exposure control (AEC)...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27776658/replacing-single-view-mediolateral-oblique-mlo-digital-mammography-dm-with-synthesized-mammography-sm-with-digital-breast-tomosynthesis-dbt-images-comparison-of-the-diagnostic-performance-and-radiation-dose-with-two-view-dm-with-or-without-mlo-dbt
#17
Hyo-Jin Kang, Jung Min Chang, Joongyub Lee, Sung Eun Song, Sung Ui Shin, Won Hwa Kim, Min Sun Bae, Woo Kyung Moon
OBJECTIVES: To evaluate the diagnostic performance and radiation dose of single view cranio-caudal (CC) digital mammography (DM) plus mediolateral oblique (MLO) digital breast tomosynthesis (DBT) combined with synthesized mammography (SM) in comparison with two-view DM with or without DBT. MATERIAL AND METHODS: This study was approved by our institutional review board, and informed consent was obtained from 130 women. Paired two-view DM and single MLO-DBT with SM images were acquired, and four independent retrospective reading sessions of different combinations of DM, SM and DBT were performed for the presence of malignant tumors using jackknife alternative free-response receiver operator curve (JAFROC) methods...
November 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27769015/breast-density-bd-assessment-with-digital-breast-tomosynthesis-dbt-agreement-between-quantra%C3%A2-and-5th-edition-bi-rads-%C3%A2
#18
Ernest U Ekpo, Claudia Mello-Thoms, Mary Rickard, Patrick C Brennan, Mark F McEntee
PURPOSE: To assess the agreement between digital breast tomosynthesis (DBT) breast density (BD) assessment made using Quantra™ and fifth edition BI-RADS(®). MATERIALS AND METHODS: This board approved study involved BD assessment of 234 women undergoing DBT investigation. BD estimation was performed from the raw DBT images using Quantra™ 3 (v.2.1.1, Hologic, Bedford MA). BI-RADS(®) assessment was performed using prior digital mammograms displayed simultaneously with 2D images synthesized from DBT by three radiologists using the fifth edition BI-RADS(®) (A, B, C, D)...
December 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27762599/dose-reduction-in-tomosynthesis-of-the-wrist
#19
Anton S Becker, Katharina Martini, Kai Higashigaito, Roman Guggenberger, Gustav Andreisek, Thomas Frauenfelder
OBJECTIVE: The purpose of this study was to quantitatively and qualitatively determine the impact of radiation dose reduction on the image noise and quality of tomosynthesis studies of the wrist. MATERIALS AND METHODS: Imaging of six cadaver wrists was performed with tomosynthesis in anteroposterior position at a tube voltage of 60 kV and tube current of 80 mA and subsequently at 60 or 50 kV with different tube currents of 80, 40, or 32 mA. Dose-area products (DAP) were obtained from the electronically logged protocol...
October 20, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27759428/comparison-of-digital-tomosynthesis-and-chest-radiography-for-the-detection-of-pulmonary-nodules-systematic-review-and-meta-analysis
#20
Jun H Kim, Kyung H Lee, Kyoung-Tae Kim, Hyun J Kim, Hyeong S Ahn, Yeo J Kim, Ha Y Lee, Yong S Jeon
OBJECTIVE: To compare the diagnostic accuracy of digital tomosynthesis (DTS) with that of chest radiography for the detection of pulmonary nodules by meta-analysis. METHODS: A systematic literature search was performed to identify relevant original studies from 1 January 1 1976 to 31 August 31 2016. The quality of included studies was assessed by quality assessment of diagnostic accuracy studies-2. Per-patient data were used to calculate the sensitivity and specificity and per-lesion data were used to calculate the detection rate...
December 2016: British Journal of Radiology
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