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https://www.readbyqxmd.com/read/29230524/one-view-digital-breast-tomosynthesis-as-a-stand-alone-modality-for-breast-cancer-detection-do-we-need-more
#1
Alejandro Rodriguez-Ruiz, Albert Gubern-Merida, Mechli Imhof-Tas, Susanne Lardenoije, Alexander J T Wanders, Ingvar Andersson, Sophia Zackrisson, Kristina Lång, Magnus Dustler, Nico Karssemeijer, Ritse M Mann, Ioannis Sechopoulos
PURPOSE: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. MATERIALS AND METHODS: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT)...
December 11, 2017: European Radiology
https://www.readbyqxmd.com/read/29206596/value-of-a-computer-aided-detection-system-based-on-chest-tomosynthesis-imaging-for-the-detection-of-pulmonary-nodules
#2
Yoshitake Yamada, Eisuke Shiomi, Masahiro Hashimoto, Takayuki Abe, Masaki Matsusako, Yukihisa Saida, Kenji Ogawa
Purpose To assess the value of a computer-aided detection (CAD) system for the detection of pulmonary nodules on chest tomosynthesis images. Materials and Methods Fifty patients with and 50 without pulmonary nodules underwent both chest tomosynthesis and multidetector computed tomography (CT) on the same day. Fifteen observers (five interns and residents, five chest radiologists, and five abdominal radiologists) independently evaluated tomosynthesis images of 100 patients for the presence of pulmonary nodules in a blinded and randomized manner, first without CAD, then with the inclusion of CAD marks...
December 4, 2017: Radiology
https://www.readbyqxmd.com/read/29190506/mammographic-density-and-breast-cancer-risk-in-breast-screening-assessment-cases-and-women-with-a-family-history-of-breast-cancer
#3
Stephen W Duffy, Oliver W E Morrish, Prue C Allgood, Richard Black, Maureen G C Gillan, Paula Willsher, Julie Cooke, Karen A Duncan, Michael J Michell, Hilary M Dobson, Roberta Maroni, Yit Y Lim, Hema N Purushothaman, Tamara Suaris, Susan M Astley, Kenneth C Young, Lorraine Tucker, Fiona J Gilbert
BACKGROUND: Mammographic density has been shown to be a strong independent predictor of breast cancer and a causative factor in reducing the sensitivity of mammography. There remain questions as to the use of mammographic density information in the context of screening and risk management, and of the association with cancer in populations known to be at increased risk of breast cancer. AIM: To assess the association of breast density with presence of cancer by measuring mammographic density visually as a percentage, and with two automated volumetric methods, Quantra™ and VolparaDensity™...
November 27, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29186172/geometric-calibration-of-a-stationary-digital-breast-tomosynthesis-system-based-on-distributed-carbon-nanotube-x-ray-source-arrays
#4
Changhui Jiang, Na Zhang, Juan Gao, Zhanli Hu
Stationary digital breast tomosynthesis (sDBT) with distributed X-ray sources based on carbon nanotube (CNT) field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based approach with seven geometric parameters, all of which can be obtained from only one projection datum of the phantom...
2017: PloS One
https://www.readbyqxmd.com/read/29176921/foveated-model-observers-to-predict-human-performance-in-3d-images
#5
Miguel A Lago, Craig K Abbey, Miguel P Eckstein
We evaluate 3D search requires model observers that take into account the peripheral human visual processing (foveated models) to predict human observer performance. We show that two different 3D tasks, free search and location-known detection, influence the relative human visual detectability of two signals of different sizes in synthetic backgrounds mimicking the noise found in 3D digital breast tomosynthesis. One of the signals resembled a microcalcification (a small and bright sphere), while the other one was designed to look like a mass (a larger Gaussian blob)...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29174225/diagnostic-accuracy-of-digital-breast-tomosynthesis-in-the-evaluation-of-palpable-breast-abnormalities
#6
Jeffrey R Hawley, Justine K Kang-Chapman, Sarah E Bonnet, Amy L Kerger, Clayton R Taylor, Barbaros S Erdal
RATIONALE AND OBJECTIVES: The role of digital breast tomosynthesis (DBT) in evaluating palpable abnormalities has not been evaluated and its accuracy compared to 2D mammography is unknown. The purpose of this study was to evaluate combined 2D mammography, DBT, and ultrasound (US) at palpable sites. MATERIALS AND METHODS: Two breast imagers reviewed blinded consecutive cases with combined 2D mammograms and DBT examinations performed for palpable complaints. By consensus, 2D and DBT findings were recorded and compared to US...
November 23, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29173918/evaluation-of-digital-tomosynthesis-reconstruction-algorithms-used-to-reduce-metal-artifacts-for-arthroplasty-a-phantom-study
#7
Tsutomu Gomi, Rina Sakai, Masami Goto, Hidetake Hara, Yusuke Watanabe, Tokuo Umeda
To investigate methods to reduce metal artifacts during digital tomosynthesis for arthroplasty, we evaluated five algorithms with and without metal artifact reduction (MAR)-processing tested under different radiation doses (0.54, 0.47, and 0.33mSv): adaptive steepest descent projection onto convex sets (ASD-POCS), simultaneous algebraic reconstruction technique total variation (SART-TV), filtered back projection (FBP), maximum likelihood expectation maximization (MLEM), and SART. The algorithms were assessed by determining the artifact index (AI) and artifact spread function (ASF) on a prosthesis phantom...
October 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/29173123/screening-digital-mammography-recall-rate-does-it-change-with-digital-breast-tomosynthesis-experience
#8
Olivia DiPrete, Ana P Lourenco, Grayson L Baird, Martha B Mainiero
Purpose To compare screening mammography recall rate, cancer detection rate (CDR), and positive predictive values (PPVs) for digital mammography before and after radiologist experience with digital breast tomosynthesis (DBT). Materials and Methods This retrospective study was approved by the institutional review board and compliant with HIPAA. The authors reviewed screening mammography audit data obtained from 2009 to 2014, during which 108 276 digital mammographic examinations were performed (50 062 before and 58 214 after experience with DBT)...
November 28, 2017: Radiology
https://www.readbyqxmd.com/read/29161236/quantitative-investigation-of-the-edge-enhancement-in-in-line-phase-contrast-projections-and-tomosynthesis-provided-by-distributing-microbubbles-on-the-interface-between-two-tissues-a-phantom-study
#9
Di Wu, Molly Donovan Wong, Yuhua Li, Laurie Fajardo, Bin Zheng, Xizeng Wu, Hong Liu
The objective of this study was to quantitatively investigate the ability to distribute microbubbles along the interface between two tissues, in an effort to improve the edge and/or boundary features in phase contrast imaging. The experiments were conducted by employing a custom designed tissue simulating phantom, which also simulated a clinical condition where the ligand-targeted microbubbles are self-aggregated on the endothelium of blood vessels surrounding malignant cells. Four different concentrations of microbubble suspensions were injected into the phantom: 0%, 0...
November 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29159881/characterization-of-photon-counting-multi-slit-breast-tomosynthesis
#10
Karl Berggren, Björn Cederström, Mats Lundqvist, Erik Fredenberg
PURPOSE: It has been shown that breast tomosynthesis may improve sensitivity and specificity compared to 2D mammography, resulting in increased detection-rate of cancers or lowered call-back rates. The purpose of this study is to characterize a spectral photon-counting multi-slit breast tomosynthesis system that is able to do single-scan spectral imaging with multiple collimated x-ray beams. The system differs in many aspects compared to conventional tomosynthesis using energy-integrating flat-panel detectors...
November 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/29153373/improving-digital-breast-tomosynthesis-reading-time-a-pilot-multi-reader-multi-case-study-using-concurrent-computer-aided-detection-cad
#11
Corinne Balleyguier, Julia Arfi-Rouche, Laurent Levy, Patrick R Toubiana, Franck Cohen-Scali, Alicia Y Toledano, Bruno Boyer
PURPOSE: Evaluate concurrent Computer-Aided Detection (CAD) with Digital Breast Tomosynthesis (DBT) to determine impact on radiologist performance and reading time. MATERIALS AND METHODS: The CAD system detects and extracts suspicious masses, architectural distortions and asymmetries from DBT planes that are blended into corresponding synthetic images to form CAD-enhanced synthetic images. Review of CAD-enhanced images and navigation to corresponding planes to confirm or dismiss potential lesions allows radiologists to more quickly review DBT planes...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29132564/tomosynthesis-in-breast-cancer-imaging-how-does-it-fit-into-preoperative-evaluation-and-surveillance
#12
REVIEW
Mohammad Eghtedari, Catherine Tsai, Julie Robles, Sarah L Blair, Haydee Ojeda-Fournier
An important limitation of conventional two-dimensional mammography is the overlap of dense breast tissue obscuring masses. Digital breast tomosynthesis (DBT) has emerged as a mammographic technology that overcomes this limitation and is considered an overall better mammogram. DBT has been shown to detect significantly more breast cancer than conventional two-dimensional mammography, and to decrease the number of callbacks for diagnostic evaluation from screening mammography. Usually the callback evaluation is deemed to be overlap of tissue requiring no further management...
January 2018: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/29131762/strengths-and-weaknesses-of-synthetic-mammography-in-screening
#13
Linda Ratanaprasatporn, Sona A Chikarmane, Catherine S Giess
Synthetic mammography (SM) consists of two-dimensional images reconstructed from digital breast tomosynthesis (DBT) data. Unlike standard full-field digital mammography (FFDM), SM does not require additional radiation exposure. SM is being introduced in breast imaging centers because early clinical data demonstrate that synthetic images are comparable to FFDM in cancer detection, positive predictive values, and recall rates. SM has completely replaced FFDM in some practices. Thus, an understanding of SM and its strengths and weaknesses compared with those of FFDM is essential...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29129518/breast-cancer-screening-with-digital-breast-tomosynthesis-4-year-experience-and-comparison-with-national-data
#14
Huay-Ben Pan, Kam-Fai Wong, Anthony Yao, Giu-Cheng Hsu, Chen-Pin Chou, Huei-Lung Liang, Jer-Shyung Huang, Hung-Ju Li, Shu-Chin Wang, Tsung-Lung Yang
BACKGROUND: To determine if mammography combined with tomosynthesis (DBT) leads to superior performance in screening for breast cancer compared to digital mammography alone. METHODS: We retrospectively collected data from A) the results of population-based mammography-screening provided by the National Cancer Registry in Taiwan, and B) the results from all screening mammography performed with DBT from 2012 through 2015 at Veterans General Hospital Kaohsiung (VGHKS) since the institution of DBT at the end of 2011...
November 9, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29125329/digital-breast-tomosynthesis-findings-may-be-different-in-her2-positive-breast-cancer-patients-according-to-hormone-receptor-status
#15
Kadri Altundag
No abstract text is available yet for this article.
November 21, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29101985/acr-appropriateness-criteria-%C3%A2-monitoring-response-to-neoadjuvant-systemic-therapy-for%C3%A2-breast-cancer
#16
Priscilla J Slanetz, Linda Moy, Paul Baron, Roberta M diFlorio, Edward D Green, Samantha L Heller, Anna I Holbrook, Su-Ju Lee, Alana A Lewin, Ana P Lourenco, Bethany Niell, Ashley R Stuckey, Sunita Trikha, Nina S Vincoff, Susan P Weinstein, Monica M Yepes, Mary S Newell
Patients with locally advanced invasive breast cancers are often treated with neoadjuvant chemotherapy prior to definitive surgical intervention. The primary aims of this approach are to: 1) reduce tumor burden thereby permitting breast conservation rather than mastectomy; 2) promptly treat possible metastatic disease, whether or not it is detectable on preoperative staging; and 3) potentially tailor future chemotherapeutic decisions by monitoring in-vivo tumor response. Accurate radiological assessment permits optimal management and planning in this population...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29101979/acr-appropriateness-criteria-%C3%A2-breast-cancer-screening
#17
Martha B Mainiero, Linda Moy, Paul Baron, Aarati D Didwania, Roberta M diFlorio, Edward D Green, Samantha L Heller, Anna I Holbrook, Su-Ju Lee, Alana A Lewin, Ana P Lourenco, Kara J Nance, Bethany L Niell, Priscilla J Slanetz, Ashley R Stuckey, Nina S Vincoff, Susan P Weinstein, Monica M Yepes, Mary S Newell
Breast cancer screening recommendations are based on risk factors. For average-risk women, screening mammography and/or digital breast tomosynthesis is recommended beginning at age 40. Ultrasound (US) may be useful as an adjunct to mammography for incremental cancer detection in women with dense breasts, but the balance between increased cancer detection and the increased risk of a false-positive examination should be considered in the decision. For intermediate-risk women, US or MRI may be indicated as an adjunct to mammography depending upon specific risk factors...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29098168/comparing-search-patterns-in-digital-breast-tomosynthesis-and-full-field-digital-mammography-an-eye-tracking-study
#18
Avi Aizenman, Trafton Drew, Krista A Ehinger, Dianne Georgian-Smith, Jeremy M Wolfe
As a promising imaging modality, digital breast tomosynthesis (DBT) leads to better diagnostic performance than traditional full-field digital mammograms (FFDM) alone. DBT allows different planes of the breast to be visualized, reducing occlusion from overlapping tissue. Although DBT is gaining popularity, best practices for search strategies in this medium are unclear. Eye tracking allowed us to describe search patterns adopted by radiologists searching DBT and FFDM images. Eleven radiologists examined eight DBT and FFDM cases...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29070984/added-value-of-digital-breast-tomosynthesis-combined-with-digital-mammography-according-to-reader-agreement-changes-in-bi-rads-rate-and-follow-up-management
#19
Francesca Galati, Flaminia Marzocca, Erica Bassetti, Maria L Luciani, Sharon Tan, Carlo Catalano, Federica Pediconi
BACKGROUND: The aim of this study was to evaluate the added value of digital breast tomosynthesis (DBT) when combined with digital mammography (DM) in BI-RADS assessment and follow-up management. METHODS: From February 2014 to January 2015, 214 patients underwent DM and DBT, acquired with a Siemens Mammomat Inspiration unit. 2 expert readers independently reviewed the studies in 2 steps: DM and DM+DBT, according to BI-RADS rate. Patients with BI-RADS 0, 3, 4, and 5 were recalled for work-up...
September 2017: Breast Care
https://www.readbyqxmd.com/read/29066138/evidence-on-synthesized-two-dimensional-mammography-versus-digital-mammography-when-using-tomosynthesis-three-dimensional-mammography-for-population-breast-cancer-screening
#20
REVIEW
Nehmat Houssami
One limitation of using digital breast tomosynthesis (3-dimensional [3D] mammography) technology with conventional (2-dimensional [2D]) mammography for breast cancer (BC) screening is the increased radiation dose from dual acquisitions. To resolve this problem, synthesized 2D (s2D) reconstruction images similar to 2D mammography were developed using tomosynthesis acquisitions. The present review summarizes the evidence for s2D versus digital mammography (2D) when using tomosynthesis (3D) for BC screening to address whether using s2D instead of 2D (alongside 3D) will yield similar detection measures...
September 28, 2017: Clinical Breast Cancer
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