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https://www.readbyqxmd.com/read/28537691/the-influence-of-previous-robotic-experience-in-the-initial-learning-curve-of-laparoscopic-radical-prostatectomy
#1
José Anastácio Dias, Marcos F Dall'oglio, João Roberto Colombo, Rafael F Coelho, William Carlos Nahas
INTRODUCTION: This study analyzed the impact of the experience with Robotic-Assisted Laparoscopic Prostatectomy (RALP) on the initial experience with Laparoscopic Radical Prostatectomy (LRP) by examining perioperative results and early outcomes of 110 patients. LRPs were performed by two ro-botic fellowship trained surgeons with daily practice in RALP. PATIENTS AND METHODS: 110 LRP were performed to treat aleatory selected patients. The patients were divided into 4 groups for prospective analyses...
May 23, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28533151/low-rates-of-androgen-deprivation-therapy-use-with-salvage-radiation-therapy-in-patients-with-prostate-cancer-after-radical-prostatectomy
#2
David D Yang, Vinayak Muralidhar, Brandon A Mahal, Michelle D Nezolosky, Shelby A Labe, Marie E Vastola, Ninjin Boldbaatar, Martin T King, Neil E Martin, Peter F Orio, Tni K Choueiri, Quoc-Dien Trinh, Robert B Den, Daniel E Spratt, Karen E Hoffman, Felix Y Feng, Paul L Nguyen
OBJECTIVE: The RTOG 9601 and GETUG-AFU 16 randomized controlled trials demonstrated that the addition of androgen deprivation therapy (ADT) to salvage radiation therapy (SRT) improves progression-free and, for RTOG 9601, overall survival. We examined national trends in the use of ADT with SRT. MATERIALS AND METHODS: Of the 484,009 patients in the National Cancer Database from 2004 to 2012 with localized or locally advanced prostate cancer treated with radical prostatectomy (RP), 4,200 men received SRT (≥6mo after surgery)...
May 19, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28532136/correlation-of-preoperative-and-radical-prostatectomy-gleason-score-examining-the-predictors-of-upgrade-and-downgrade-results
#3
Gholamreza Pourmand, Shahram Gooran, Seyed Reza Hossieni, Fateme Guitynavard, Majid Safavi, Amirsina Sharifi, Ehsan Mokhtari
Preoperative Gleason score (GS) obtained from Trans Rectal Ultra Sonography (TRUS) is the most common grading system to evaluate the appropriate treatment for patients with clinically localized prostate cancer. But this method showed upgraded and downgraded results in comparison to Gleason score obtained from radical prostatectomy. The current study aimed to determine clinical or pathological variables to reduce the differences between biopsy and radical prostatectomy Gleason scores.Through retrospective review of 52 patients with radical prostatectomy, this study examined the correlations of preoperative Gleason score with age, prostate volume, PSA level, PSA density, digital rectal exam findings and percentage of positive core needle biopsies across two groups, including patients with preoperative GS≤6 (i...
April 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28530629/-laparoendoscopic-single-site-less-ureteral-reimplantation
#4
Pedro M Cabrera Castillo, Felipe Cáceres Jiménez
OBJECTIVE: To present in detail our surgical technique and to show our initial experience with ureteral reimplantation using the transumbilical LESS approach to treat patients with ureteral stenosis secondary to various diseases and surgical complications. METHODS: We performed 7 ureteral reimplantations from February 2012, using the multichannel Richard- Wolf (KeyPort) platform placed transumbilical by a small 2-2,5 cm transversal incision. We always use a 3.5 mm minilaparoscopy accessory trocar in the right iliac fossa, that is crucial to perform the laparoscopic suturing safely for the patient and in an optimal time...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530220/presence-of-invasive-cribriform-or-intraductal-growth-at-biopsy-outperforms-percentage-grade-4-in-predicting-outcome-of-gleason-score-3-4-7-prostate-cancer
#5
Charlotte F Kweldam, Intan P Kümmerlin, Daan Nieboer, Ewout W Steyerberg, Chris H Bangma, Luca Incrocci, Theodorus H van der Kwast, Monique J Roobol, Geert J van Leenders
Relative increase of grade 4 and presence of invasive cribriform and/or intraductal carcinoma have individually been associated with adverse outcome of Gleason score 7 (GS 7) prostate cancer. The objective of this study was to investigate the relation of Gleason grade 4 tumor percentage (%GG4) and invasive cribriform and/or intraductal carcinoma in GS 3+4=7 prostate cancer biopsies. We reviewed 1031 prostate cancer biopsies from the European Randomized Study of Screening for Prostate Cancer. In total 370 men had G3+4=7...
May 19, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28529746/morphological-changes-in-peri-prostatic-sympathetic-ganglion-cells-in-aging-males
#6
Lea Rath-Wolfson, Asaf Shvero, Golan Bubis, Galina Buzaverov, Aliza Zeidman, Edward Ram, Rumelia Koren
A significant part of morbidity in elderly male patients involves the pelvic organs and their autonomic neural regulation. The aim of the current study was to report the histopathological changes in the peri-prostatic ganglia in elderly males. The sympathetic ganglia from 36 prostatectomy specimens, 26 due to carcinoma of the prostate and 10 prostates from total cystectomies for transitional cell carcinoma, were examined. The age range was 54-88 years. A total of 5,075 ganglion cells were counted in all the specimens...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28528811/ability-of-a-genomic-classifier-to-predict-metastasis-and-prostate-cancer-specific-mortality-after-radiation-or-surgery-based-on-needle-biopsy-specimens
#7
Paul L Nguyen, Zaid Haddad, Ashley E Ross, Neil E Martin, Samineh Deheshi, Lucia L C Lam, Jijumon Chelliserry, Jeffrey J Tosoian, Tamara L Lotan, Daniel E Spratt, Radka S Stoyanova, Sanoj Punnen, Kaye Ong, Christine Buerki, Maria Aranes, Tyler Kolisnik, Jennifer Margrave, Kasra Yousefi, Voleak Choeurng, Elai Davicioni, Bruce J Trock, Christopher J Kane, Alan Pollack, John W Davis, Felix Y Feng, Eric A Klein
BACKGROUND: Decipher is a validated genomic classifier developed to determine the biological potential for metastasis after radical prostatectomy (RP). OBJECTIVE: To evaluate the ability of biopsy Decipher to predict metastasis and Prostate cancer-specific mortality (PCSM) in primarily intermediate- to high-risk patients treated with RP or radiation therapy (RT). DESIGN, SETTING, AND PARTICIPANTS: Two hundred and thirty-five patients treated with either RP (n=105) or RT±androgen deprivation therapy (n=130) with available genomic expression profiles generated from diagnostic biopsy specimens from seven tertiary referral centers...
May 18, 2017: European Urology
https://www.readbyqxmd.com/read/28528448/prostate-cancer-related-anxiety-in-long-term-survivors-after-radical-prostatectomy
#8
Valentin H Meissner, Kathleen Herkommer, Birgitt Marten-Mittag, Jürgen E Gschwend, Andreas Dinkel
PURPOSE: Knowledge of the psychological distress of long- and very long-term (>10 years) prostate cancer (PC) survivors is limited. This study intended to examine the parameters influencing anxiety related to prostate-specific antigen (PSA) and PC in long-term survivors after radical prostatectomy. METHODS: We surveyed 4719 PC survivors from the German multicenter prospective database "Familial Prostate Cancer." We evaluated the association of PC-related anxiety (MAX-PC) with sociodemographic characteristics, family history of PC, global health status/quality of life (EORTC QLQ-C30), depression and anxiety (PHQ-2; GAD-2), latest PSA level, time since radical prostatectomy, and current therapy...
May 21, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28526916/-salvage-radiotherapy-with-antiandrogen-therapy-after-prostatectomy-significant-overall-survival-benefit-compared-to-radiotherapy-alone
#9
Gregor Goldner
No abstract text is available yet for this article.
May 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28526462/-sudden-motor-and-sensorial-loss-due-to-retroperitoneal-hematoma-during-postoperative-periods-a-case-report
#10
Pelin Şen, Havva Gül Gültekin, İsmail Caymaz, Ömer Özel, Ayda Türköz
A 68 year-old male patient was hospitalized for radical prostatectomy. He had no abnormal medical history including neurological deficit before the operation. Prior to general anesthesia, an epidural catheter was inserted in the L3-4 interspace for intraoperative and postoperative analgesia. After surgery for nine hours, he developed confusion and flaccid paralysis of bilateral lower extremities occurred. No pathology was detected from cranial computed tomography and diffusion magnetic resonance imaging no pathology was detected...
May 16, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28525665/urinary-artificial-sphincter-zsi-375-for-treatment-of-stress-urinary-incontinence-in-men-5-and-7-years-follow-up-report
#11
Christophe Llorens, Tobias Pottek
STUDY DESIGN: This is a retrospective, non-randomised study. OBJECTIVES: The aim of this study was to evaluate safety and efficacy of artificial urinary sphincter ZSI 375 inserted in male patients with stress urinary incontinence (SUI). METHODS: Between May 2009 and January 2017, 45 men with SUI underwent ZSI 375 device insertion. Operations were performed in two French centres by one surgeon. Complications and pad used to manage continence were recorded...
May 18, 2017: Urologia
https://www.readbyqxmd.com/read/28525664/near-infrared-fluorescence-with-indocyanine-green-for-diagnostics-in-urology-initial-experience
#12
Andrey O Morozov, Yuri G Alyaev, Leonid M Rapoport, Dmitrii G Tsarichenko, Eugene A Bezrukov, Denis V Butnaru, Eugene S Sirota
INTRODUCTION: Fluorescence imaging with indocyanine green is used in urology for the detection of sentinel lymph nodes and identification of prostate margins in radical prostatectomy for delineation of resection zone and selective clamping of vessels in partial nephrectomy; for identification and evaluation of length of ureteral strictures; for assessment of perfusion and viability of anastomoses during reconstructive stage of cystectomy. Safety of this technique is proven, while its diagnostic value and usefulness is still controversial...
May 16, 2017: Urologia
https://www.readbyqxmd.com/read/28525448/18f-fluorocholine-pet-ct-complementing-the-role-of-dynamic-contrast-enhanced-mri-for-providing-comprehensive-diagnostic-workup-in-prostate-cancer-patients-with-suspected-relapse-following-radical-prostatectomy
#13
Shelvin Kumar Vadi, Baljinder Singh, Rajender K Basher, Ankit Watts, Ashwani K Sood, Anupam Lal, Nandita Kakkar, S K Singh
PURPOSE: The aim of this study was to compare the diagnostic performance of F-fluorocholine (FCH) PET/CT and dynamic contrast-enhanced MRI (DCE-MRI) of pelvis in restaging prostate cancer (PC) patients with biochemical recurrence (BCR) following radical prostatectomy (RP). METHODS: Twenty PC patients who had undergone RP and had BCR were recruited in this study. All the patients underwent whole-body FCH PET/CT and DCE-MRI of the pelvis. An overall pattern of recurrent disease was analyzed, and diagnostic accuracy for the detection of pelvic disease recurrence by the 2 modalities was evaluated by taking histopathologic analysis as the criterion standard...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28523407/heterogeneous-oncologic-outcomes-according-to-surgical-pathology-in-high-risk-prostate-cancer-implications-for-better-risk-stratification-and-preoperative-prediction-of-oncologic-outcomes
#14
Seung-Kwon Choi, Myungsun Shim, Myong Kim, Myungchan Park, Sangmi Lee, Cheryn Song, Hyung-Lae Lee, Hanjong Ahn
PURPOSE: To evaluate the better risk stratification based on surgical pathology, and to predict oncologic outcomes after radical prostatectomy (RP) with a better scoring system in high-risk prostate cancer (PCa) patients. METHODS: We evaluated high-risk PCa patients (PSA >20 ng/ml, ≥cT3a, or Gleason score 8-10) who underwent RP between 2007 and 2013 at our institute. We classified patients into three groups according to their pathologic outcomes: favorable (pT2, Gleason score ≤7, and node negative), intermediate (specimen-confined disease (pT2-3a, node negative PCa with negative surgical margins) but not in the favorable group), and unfavorable (the remaining patients)...
May 18, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28522740/initial-experience-with-volumetric-68-ga-psma-i-t-pet-ct-for-assessment-of-whole-body-tumor-burden-as-a-quantitative-imaging-biomarker-in-patients-with-prostate-cancer
#15
Sebastian Schmuck, Christoph A von Klot, Christoph Henkenberens, Jan M Sohns, Hans Christiansen, Hans-Jürgen Wester, Tobias L Ross, Frank M Bengel, Thorsten Derlin
A quantitative imaging biomarker is desirable to provide a comprehensive measure of whole-body tumor burden in patients with metastatic prostate cancer, and to standardize the evaluation of treatment-related changes. Therefore, we evaluated whether prostate specific membrane antigen (PSMA) ligand positron emission tomography/computed tomography (PET/CT) may be applied to provide PSMA-derived volumetric parameters for quantification of whole-body tumor burden. Methods: 101 patients who underwent a (68)Ga-PSMA I&T PET/CT because of increasing prostate specific antigen (PSA) levels after radical prostatectomy were included in this retrospective analysis...
May 18, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28522288/grade-group-underestimation-in-prostate-biopsy-predictive-factors-and-outcomes-in-candidates-for-active-surveillance
#16
François Audenet, François Rozet, Matthieu Resche-Rigon, Rémy Bernard, Alexandre Ingels, Dominique Prapotnich, Rafael Sanchez-Salas, Marc Galiano, Eric Barret, Xavier Cathelineau
OBJECTIVE: We intended to analyze the outcomes and predictive factors for underestimating the prostate cancer (PCa) grade group (GG) from prostate biopsies in a large monocentric cohort of patients treated by minimally invasive radical prostatectomy (RP). MATERIALS AND METHODS: Using a monocentric prospectively maintained database, we included 3062 patients who underwent minimally invasive RP between 2006 and 2013. We explored clinicopathologic features and outcomes associated with a GG upgrade from biopsy to RP...
April 26, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28520339/reply-by-the-authors-re-artificial-urinary-sphincter-for-urinary-incontinence-after-radical-prostatectomy-a-historical-cohort-from-2004-to-2015
#17
Augusto Cesar Soares Dos Santos, Luíza de Oliveira Rodrigues, Daniela Castelo Azevedo, Lélia Maria de Almeida Carvalho, Mariana Ribeiro Fernandes, Sandra de Oliveira Sapori Avelar, Maria Glória Cruvinel Horta, Silvana Márcia Bruschi Kelles
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28520338/re-artificial-urinary-sphincter-for-urinary-incontinence-after-radical-prostatectomy-a-historical-cohort-from-2004-to-2015
#18
Jose Carlos Truzzi, Carlos Alberto Ricetto Sacomani, Jose Antonio Prezzoti
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28520337/pde-5-inhibitors-should-be-used-post-radical-prostatectomy-as-erection-function-rehabilitation-opinion-no
#19
EDITORIAL
Jonathan Clavell-Hernández, Run Wang
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28520336/pde-5-inhibitors-should-be-used-post-radical-prostatectomy-as-erection-function-rehabilitation-opinion-yes
#20
EDITORIAL
Laith M Alzweri, Arthur L Burnett
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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