Christine U Lee, Matthew W Urban, Gina K Hesley, Benjamin G Wood, Thomas R Meier, Beiyun Chen, Blake A Kassmeyer, Nicholas B Larson, A Lee Miller, James L Herrick, James W Jakub, Mara A Piltin
OBJECTIVE: We have studied the use of polymethyl methacrylate (PMMA) as an alternative biopsy marker that is readily detectable with ultrasound Doppler twinkling in cases of in vitro, ex vivo, or limited duration in vivo settings. This study investigates the long-term safety and ultrasound Doppler twinkling detectability of a PMMA breast biopsy marker following local perturbations and different dwell times in a 6-mo animal experiment. METHODS: This study, which was approved by our Institutional Animal Care and Use Committee, involved three pigs and utilized various markers, including PMMA (Zimmer Biomet), 3D-printed, and Tumark Q markers...
April 3, 2024: Ultrasound in Medicine & Biology