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https://www.readbyqxmd.com/read/29771187/advanced-stage-breast-cancer-is-associated-with-catheter-tip-thrombus-formation-following-implantable-central-venous-port-placement
#1
Mina S Makary, Alexander Lionberg, Mamdouh Khayat, Maryam B Lustberg, Jamal AlTaani, Xueliang J Pan, Richard R Layman, Subha V Raman, Rachel M Layman, Joshua D Dowell
Purpose Catheter-tip associated thrombosis is not uncommon in patients with implantable central venous ports; however, the prevalence and clinical impact of this complication on patient management is unclear. This study aims to identify risk factors for thrombus formation in a large population receiving serial echocardiograms (echo) following port placement. Methods A total of 396 female breast cancer patients underwent internal jugular vein chest port placement between 2007 and 2013 and received echo studies every third month...
January 1, 2018: Phlebology
https://www.readbyqxmd.com/read/29770862/is-latin-america-ready-to-identify-anaplastic-large-cell-lymphoma-in-breast-implants-patients-regional-encounter-during-the-national-plastic-surgery-meeting-in-cancun-mexico
#2
EDITORIAL
Guillermo Ramos-Gallardo, Jesus Cuenca-Pardo, Lazaro Cardenas-Camarena, Hector Duran-Vega, Eugenio Rodríguez-Olivares, Jorge Enrique Bayter-Marin, Gerardo Levelier De Doig Alvear, Guillermo Vazquez, Montserrat Fontbona-Torres, Ricardo Galán-Suárez, Gabriela Guzman-Stein, Sergio Guzmán-Padilla, Guillermo Echeverría-Roldán, Jose Fernando Silva-Gavarrete, Alfonso Vallarta-Rodríguez, Livia Contreras-Bulnes, Carlos Guillemro Oaxaca-Escobar, Isabel Caravantes-Cortes, María Eugenia Flores, Jorge Cowes-McGowen, María Liz Maciel-Sosa, Ricardo Delgado-Binasco, Linda Rincón-Rubio
INTRODUCTION: Anaplastic large cell lymphoma associated with breast implants is receiving increased attention. Most cases have been reported in Europe, North America (USA and Canada), Australia and New Zealand. Fewer cases have been reported in Latin America (including Mexico), Africa and Asia. METHODS: This report was delivered during our national plastic surgery meeting in Cancun in May 2017. Before the meeting, two participants reviewed the literature. The review was performed using the following information sources: PubMed, Embase, Cochrane, Fisterra, Google Scholar and LILACS, with entries from 1980 to August 2015 in several languages (English, Spanish, French and Portuguese)...
May 16, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29767713/commentary-on-hypochlorous-acid-versus-povidone-iodine-containing-irrigants-which-antiseptic-is-more-effective-for-breast-implant-pocket-irrigation
#3
Roger N Wixtrom
No abstract text is available yet for this article.
May 14, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29758415/anti-tumor-effects-of-propranolol-adjuvant-activity-on-a-transplanted-murine-breast-cancer-model
#4
Somayeh Ashrafi, Reza Shapouri, Ahmad Shirkhani, Mehdi Mahdavi
Propranolol (Pro), a non-specific β-adrenergic blocking drug, competitively prevents the binding of catecholamines to receptors and suppresses cancer cells. The anti-tumor activity of propranolol has been proved in different kinds of cancers. In this study, we assessed the adjuvant activity of propranolol combined with a tumor vaccine model on the immunological parameters of breast tumor-bearing mice. Breast tumor pieces were implanted into the flank of inbred BALB/C female mice from stock mice. Tumor-bearing mice were treated with tumor antigen lysate vaccine and propranolol/Vaccine (Pro/Vac) combination (as treatment groups), propranolol and PBS (as control groups) for 5 consecutive days, every 12 h...
May 11, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29757359/commentary-on-novel-proteomic-assay-of-breast-implants-reveals-proteins-with-significant-binding-differences-implications-for-surface-coating-and-biocompatibility
#5
https://www.readbyqxmd.com/read/29756165/study-on-the-dose-modification-factor-of-strut-adjusted-volume-implant-savi-with-a-169-yb-source-using-mcnp4c
#6
Seyed Milad Vahabi, Mostean Bahreinipour, Mojtaba Shamsaie Zafarghandi
The SAVI has gained widespread use for accelerated partial breast irradiation (APBI) brachytherapy. Treatments with SAVI produce inherent heterogeneities including variable backscatter due to proximity to the tissue-air interface and variable cavity contents, causing inaccuracy in the dose calculation. In this study, a model of SAVI with sources of 169 Yb developed recently was defined and simulations with MCNP4C code of Monte Carlo were performed through different scenarios to assess the effects of these heterogeneities on the dose distribution...
May 13, 2018: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/29755559/inhibitory-effect-of-viola-odorata-extract-on-tumor-growth-and-metastasis-in-4t1-breast-cancer-model
#7
Hiva Alipanah, Mohammad Reza Bigdeli, Mohammad Ali Esmaeili
Viola odorata as a medical herb is used in liver disorders and relieving cancer pain. In the present study, the cytotoxic, antioxidant, and anti-metastatic properties of Viola odorata hydro-alcoholic extract (VOE) were investigated in 4T1 breast cancer model. After treatment of 4T1 breast cancer cells with VOE, cell viability was measured by MTT assay. The implanted mice were treated with different concentration of VOE (50, 150 and 250 mg/kg) for 21 days. Levels of lactate dehydrogenase (LDH), γ -glutamyl transferase (GGT), alkaline phosphatase (ALP), carcinoembryonic antigen (CEA) and cancer antigen 15-3(CA15-3) in serum, and also catalase (CAT) and superoxide dismutase (SOD) activities in tumor tissue were measured...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29750761/-toradol%C3%A2-following-breast-surgery-is-there-an-increased-risk-of-hematoma
#8
Brittany N Nguyen, Ruth J Barta, Christine Stewart, Cherrie A Heinrich
BACKGROUND: Ketorolac tromethamine (Toradol), a nonsteroidal antiinflammatory drug, is used with increased frequency given its success in postoperative pain control and the subsequent decreased need for narcotics. Its use has been limited in plastic surgery for fear of postoperative bleeding and hematoma formation. In this study of breast surgery patients, we investigated whether ketorolac increased the risk of postoperative hematoma formation. METHODS: After obtaining institutional review board approval, we retrospectively reviewed the records of patients undergoing breast surgery (breast reduction and autologous or implant based reconstruction) from January 2012 through December 2014...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29750759/immediate-two-stage-prosthetic-breast-reconstruction-failure-radiation-is-not-the-only-culprit
#9
Thomas C Lam, Robert Borotkanics, Frank Hsieh, James Salinas, John Boyages
BACKGROUND: Immediate prosthetic breast reconstruction produces a satisfactory aesthetic result with high levels of patient satisfaction. However, with the broader indication for post-mastectomy adjuvant radiation, many patients are advised against immediate breast reconstruction because of concerns of implant loss and infection particularly as most patients also require chemotherapy. This retrospective cohort study examines outcomes for patients who underwent immediate two-stage prosthetic breast reconstruction after mastectomy with or without adjuvant chemotherapy or radiotherapy (RT)...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29746276/deepithelialized-skin-reduction-preserves-skin-and-nipple-perfusion-in-immediate-reconstruction-of-large-and-ptotic-breasts
#10
Danielle H Rochlin, Dung H Nguyen
BACKGROUND: Women with large and/or ptotic breasts are often not considered candidates for nipple-sparing mastectomy (NSM) and/or immediate breast reconstruction given difficulties avoiding ischemic complications and achieving a favorable aesthetic result. We report a novel technique involving deepithelialized skin reduction to simultaneously reduce the skin envelope and preserve perfusion to the skin and nipple in immediate breast reconstruction for women that fit this high-risk anatomic profile...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29746274/combined-autologous-and-prosthetic-breast-reconstruction-defining-the-upper-limits-of-safe-expansion-in-obesity
#11
Joshua H Choo, Thomas J Lee, Steven A Schulz, Mitchell Buller, Bradon J Wilhelmi
BACKGROUND: Combined latissimus dorsi and prosthetic reconstruction is a useful reconstructive option in patients with a history of breast radiation who are not good candidates for abdominally based autologous reconstruction. One difficulty, particularly in obese patients, is that the thickness of the flap can impair port localization, increasing the risk of inadvertent puncture during expansion. The authors sought to investigate the upper limits of tissue thickness at which tissue expansion can be reliably performed...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29741462/complications-risk-factors-and-patients-reported-outcomes-after-skin-sparing-mastectomy-followed-by-breast-reconstruction-in-women-with-brca-mutations
#12
Ingvild O Moberg, Inger Schou Bredal, Michael R Schneider, Kim A Tønseth, Ellen Schlichting
BACKGROUND: Women with a BRCA mutation have the option of undergoing prophylactic mastectomy and immediate breast reconstruction; however, the potential negative effects of reconstruction on women's physical and psychological well-being are unclear. This study aimed to investigate complications, patient-reported pain, health-related quality-of-life (HRQoL) and satisfaction following reconstructive surgery at Oslo University Hospital between 2006 and 2013. METHODS: Data were collected retrospectively from the records of 238 patients...
May 9, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29741263/the-2017-who-update-on-mature-t-and-natural-killer-nk-cell-neoplasms
#13
REVIEW
E Matutes
Over the last decade, there has been a significant body of information regarding the biology of the lymphoid neoplasms. This clearly supports the need for updating the 2008 WHO (World Health Organization) classification of haematopoietic and lymphoid tumours. The 2017 WHO classification is not a new edition but an update and revision of the 4th edition. New provisional entities but not new definitive entities are included, and novel molecular data in most of the entities and changes in the nomenclature in few of them have been incorporated...
May 2018: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/29740971/target-position-reproducibility-in-left-breast-irradiation-with-deep-inspiration-breath-hold-using-multiple-optical-surface-control-points
#14
Aurora Fassi, Giovanni B Ivaldi, Paola Tabarelli de Fatis, Marco Liotta, Ilaria Meaglia, Patrizia Porcu, Lea Regolo, Marco Riboldi, Guido Baroni
The aim of this study was to investigate the use of 3D optical localization of multiple surface control points for deep inspiration breath-hold (DIBH) guidance in left-breast radiotherapy treatments. Ten left-breast cancer patients underwent whole-breast DIBH radiotherapy controlled by the Real-time Position Management (RPM) system. The reproducibility of the tumor bed (i.e., target) was assessed by the position of implanted clips, acquired through in-room kV imaging. Six to eight passive fiducials were positioned on the patients' thoraco-abdominal surface and localized intrafractionally by means of an infrared 3D optical tracking system...
May 8, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29736675/influence-of-flap-thickness-on-nipple-projection-after-nipple-reconstruction-using-a-modified-star-flap
#15
Naohiro Ishii, Jiro Ando, Michiko Harao, Masaru Takemae, Kazuo Kishi
BACKGROUND: In nipple reconstruction, the width, length, and thickness of modified star flaps are concerns for long-term reconstructed nipple projection. However, the flap's projection has not been analyzed, based on its thickness. The aim of the present study was to investigate how flap thickness in a modified star flap influences the resulting reconstructed nipple and achieves an appropriate flap width in design. METHODS: Sixty-three patients who underwent nipple reconstruction using a modified star flap following implant-based breast reconstruction between August 2014 and July 2016 were included in this case-controlled study...
May 7, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29736283/chronic-pulmonary-silicone-embolism-from-breast-augmentation-is-not-a-common-finding-in-explanted-lungs
#16
Jarmanjeet Singh, Hanine Inaty, Sanjay Mukhopadhyay, Atul C Mehta
Objective: Acute pulmonary silicone embolism (APSE) related to subcutaneous silicone injections is a well-known entity. Recently, a few cases of pathologically confirmed chronic pulmonary silicone embolism (CPSE) from breast implants have been reported. The prevalence of CPSE in women with breast augmentation is unknown. This study was done to determine the prevalence of CPSE in female lung transplant recipients with a history of breast augmentation and to determine whether breast augmentation plays a role in chronic lung diseases requiring lung transplantation...
2018: Pulmonary Medicine
https://www.readbyqxmd.com/read/29734445/a-multicenter-analysis-examining-patients-undergoing-conversion-of-implant-based-breast-reconstruction-to-abdominally-based-free-tissue-transfer
#17
Ruya Zhao, Bao Ngoc N Tran, Andres F Doval, Gloria Broadwater, Kate J Buretta, Jonah P Orr, Bernard T Lee, Scott T Hollenbeck
BACKGROUND:  Breast implant placement is the most common method for postmastectomy reconstruction. For patients who develop complications associated with implant-based reconstruction, additional surgeries may be challenging. This study examined implant-based reconstruction failure in patients undergoing salvage with abdominal free tissue transfer. METHODS:  We conducted an Institutional Review Board approved, multicenter retrospective study of patients with implant-based primary breast reconstruction followed by implant removal and subsequent abdominal free tissue transfer between 2006 and 2016...
May 7, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29729897/injectable-magnetic-supramolecular-hydrogel-with-magnetocaloric-liquid-conformal-property-prevents-the-post-operative-recurrence-in-a-breast-cancer-model
#18
Haoan Wu, Lina Song, Ling Chen, Wei Zhang, Yi Chen, Fengchao Zang, Hong Chen, Ming Ma, Ning Gu, Yu Zhang
Locoregional recurrence of breast cancer after tumor resection represents several clinical challenges. Here, we demonstrate that co-delivery of chemotherapy and thermotherapeutic agents by a magnetic supramolecular hydrogel (MSH) following tumor resection prevents tumor recurrence in a breast cancer mouse model. The self-assembled MSH was designed through the partial inclusion complexation associated with the threading of α-CD on the copolymer moieties on the surface of the PEGylated iron oxide (Fe3 O4 ) nanoparticles, which enables shear-thinning injection and controllable thermoreversible gel-sol transition...
May 3, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29727209/perturbation-of-epithelial-apicobasal-polarity-by-rhomboid-family-1-gene-overexpression
#19
Xue-Mei Peng, Shan Gao, Hui-Ting Deng, Hong-Xing Cai, Zhuan Zhou, Rong Xiang, Qiang-Zhe Zhang, Lu-Yuan Li
The human rhomboid family (RHBDF)1 gene is highly expressed in breast cancer under clinical conditions but not in normal mammary gland tissues. Silencing the RHBDF1 gene in breast cancer xenograft tumors leads to inhibition of tumor growth. We show in this study that artificially raising RHBDF1 protein levels in the mammary epithelial cells MCF-10A results in severe perturbations of the ability of the cells to form lumen-containing acini, either in 3-dimensional cell cultures or implanted in mouse mammary fat pads...
May 4, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29726913/breast-implant-registries-a-call-to-action
#20
Ingrid Hopper, Susannah Ahern, Tu Q Nguyen, Catherine Mulvany, John J McNeil, Anand K Deva, Howard Klein, Birgit Stark, Hinne A Rakhorst, Rodney D Cooter
No abstract text is available yet for this article.
May 3, 2018: Aesthetic Surgery Journal
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