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https://www.readbyqxmd.com/read/29682106/nitric-oxide-from-good-to-bad
#1
REVIEW
Paul M Vanhoutte
This essay summarizes a lecture presented on October 19th, 2017, during the 58th Annual Meeting of the Japanese College of Angiology in Nagoya, Japan. The lecture summarizes several instances where the absence of relaxations of isolated blood vessels in response to endothelium-dependent vasodilator agonists, which cause activation of endothelial nitric oxide synthase (eNOS) and consequent production of endothelium-derived nitric oxide (NO) and stimulation of soluble guanylyl cyclase (sGC) in underlying vascular smooth muscle, or hypoxia are curtailed or reversed to endothelium-dependent contractions...
March 25, 2018: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29577764/-immunoadsorption-in-a-patient-with-dilated-cardiomyopathy-the-first-case-in-hungary
#2
Pál Soltész, Melinda Vass, Ágnes Diószegi, Ivetta Mányiné Siket, Ildikó Garai, Csaba Kun, Orsolya Bene, Attila Kertész, István Édes
Dilated cardiomyopathy is the main cause of heart transplantation. The etiology is unknown in almost half of the cases. Many cardiac specific antibodies have been identified till now which can cause decreased cardiac function, ventricular tachycardia or sudden heart death. The prognosis of DCM is poor despite the development of medical treatment. Immunoadsorption is hopeful since, with the removal of antibodies, cardiac function and NYHA class can improve and LVAD/heart transplantation-free survival can be prolonged...
April 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29552442/carotid-strain-measurement-in-patients-with-pseudoxanthoma-elasticum-hint-for-a-different-pathomechanism
#3
Sebastian Gorgonius Passon, Viviane Küllmar, Anna Katharina Blatzheim, Kristin Solveig Pausewang, Max Jonathan Stumpf, Doris Hendig, Martin Gliem, Simon Pingel, Robert Schueler, Dirk Skowasch, Najib Schahab, Georg Nickenig, Christian Alexander Schaefer
Pseudoxanthoma Elasticum (PXE), caused by autosomal-recessive mutations in the ATP-binding cassette transporter (ABCC6) gene, is known for high prevalence of atherosclerosis. A novel method investigating elastic properties of arteries in atherosclerotic patients is vascular strain analysis. We compared 44 PXE patients with peripheral artery disease (PXE+PAD group) with 50 control patients, each 25 without (control group) and with PAD (PAD group). All participants underwent an angiological examination including ankle-brachial index (ABI) and were examined with speckle-tracking based vascular strain analysis of common carotid arteries, measuring radial displacement (r...
February 2018: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/29507564/the-usefulness-of-duplex-doppler-ultrasound-in-the-angiological-and-dermatological-diagnosis-of-patients-with-blue-toe-syndrome
#4
Katarzyna Pawlaczyk, Marcin Gabriel, Daria A Strzelecka-Węklar, Zbigniew Krasiński, Michal Stanisic, Zofia Gabriel, Łukasz Dzieciuchowicz, Zygmunt Adamski
Introduction: Peripheral microembolism is one of the most frequent causes of acute limb ischemia. In order to effectively prevent relapses it is essential to localize and eliminate the source of embolism. Aim: To evaluate the role of Duplex Doppler ultrasound examination in identifying the causes of blue toe syndrome (BTS). Material and methods: The group of 165 patients with clinical symptoms of BTS on their upper limbs ( n = 16) and lower limbs ( n = 149) was investigated...
October 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29498878/-effect-of-pulsatility-on-markers-of-vascular-damage-in-patients-with-implanted-continuous-flow-mechanical-circulatory-support
#5
Peter Ivák, Jan Piťha, Ivana Králová Lesná, Ivan Netuka
Ventricular assist devices are an important therapeutic modality in advanced surgical therapy of end-stage heart failure. Previously most frequently used devices generated mainly non-pulsatile blood flow. Despite indisputable clinical success of this therapy, we encounter complications specific to the devices generating continuous flow. Complications are mainly attributed to changes in shear stress and subsequent changes of the blood vessel characteristics, mainly of endothelium. Effect of continuous flow on the vasculature and blood elements, therefore, became a subject of intense recent research...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29471558/indication-technique-and-long-term-results-after-shoulder-arthrodesis-performed-with-plate-fixation
#6
Ulrich Irlenbusch, Olaf Rott, Lars Irlenbusch
AIM: Arthrodesis of the shoulder joint is a radical event, so it is difficult to explain its significance to patients. It has been the last resort in hopeless cases. Knowledge of long-term results and evaluation of advantages and disadvantages seems to be helpful in this regard. METHODS: Eleven patients with mean age of 45 (31 - 58) years were operated between 2000 and 2013. All patients could be included in the investigation (FU mean 8.5 [3 - 16] years; 8 male and 3 female; right 9, left 2)...
February 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29412008/subtraction-ct-angiography-in-head-and-neck-with-low-radiation-and-contrast-dose-dual-energy-spectral-ct-using-rapid-kv-switching-technique
#7
Guangming Ma, Yong Yu, Haifeng Duan, Yuequn Dou, Yongjun Jia, Xirong Zhang, Chuangbo Yang, Xiaoxia Chen, Dong Han, Changyi Guo, Taiping He
OBJECTIVE: To investigate the application of low radiation and contrast dose spectral CT angiology using rapid kV-switching technique in the head and neck with subtraction method for bone removal. METHODS: This prospective study was approved by the local ethics committee. 64 cases for head and neck CT angiology were randomly divided into Groups A (n = 32) and B (n = 32). Group A underwent unenhanced CT with 100 kVp, 200 mA and contrast-enhanced CT with spectral CT mode with body mass index-dependent low dose protocols...
March 7, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29337442/-angiology-and-haemostasis-highlights-on-some-new-data-in-2017
#8
Pierre Fontana, Helia Robert-Ebadi, Françoise Boehlen, Marc Righini
New data support the fact that prophylactic anticoagulation with direct oral anticoagulants is effective and safe for the long-term prevention of venous thromboembolism. This type of treatment is dedicated for a subgroup of patients only, which is described in this article. With regard to major bleedings occurring with these anticoagulants, new data have been added to those already available for idarucizumab, a specific antagonist of dabigatran. Finally, we summarize the data regarding a breakthrough molecule, emicizumab, which could potentially open a new era in the management of people with haemophilia A...
January 10, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29212334/-hyperlipoprotienemias-and-not-only-atherosclerosis-fragments-from-history-and-present
#9
Richard Češka
The examples from the history, as well as the recent view, clearly demonstrate a great change in the perception of hyperlipoprotienemias and dyslipidemias (HLP and DLP) at the end of 20th and at the beginning of 21st century. Our aim is not a complex overview about HLP and DLP. We just want to describe the changing position and importance of these diseases in clinical medicine. We will touch cardiology, angiology, but also diabetology, hepatology and gastroenterology (pancreas). HLP and DLP, which started as a research topic in laboratory became clinically interesting as risk factors of atherosclerosis...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29147169/uncomplicated-acute-type-b-aortic-dissection-selection-guidelines-for-tevar
#10
Emilia Krol, Jean M Panneton
Traditionally, the surgical management of acute type B aortic dissections was reserved for patients with signs of malperfusion, rapid expansion, retrograde dissection or rupture. The adjunct of endovascular techniques has brought a paradigm shift, leaning towards preventing long term dissection complications. Multiple risk factors have been proposed to identify patients at risk for long term aortic complications. The patients, who are offered a prophylactic endovascular therapy for uncomplicated aortic dissection, should be selected carefully, and offered intervention by an experienced team in a high-volume center...
September 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29081660/implementing-clinical-process-management-of-vascular-wounds-in-a-tertiary-facility-impact-evaluation-of-a-performance-improvement-project
#11
Giampiero Avruscio, Ilaria Tocco-Tussardi, Greta Bordignon, Vincenzo Vindigni
BACKGROUND: Chronic vascular wounds have a significant economic and social impact on our society calling for allocation of a great deal of attention and resources. Efforts should be oriented toward the achievement of the most effective and efficient clinical management. The Angiology Unit at the University Hospital of Padova, Italy, developed a performance improvement project to enhance the quality of practice for vascular ulcers. METHODS: The project consisted in a multistep process comprising a critical revision of the previous clinical process management, staff education, tightening connections between operators and services, and creation of a position for a wound care nurse...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28832093/-heart-without-smoke-educational-campaign-the-role-of-patient-education-in-secondary-prevention-of-cardiovascular-disease
#12
Zbigniew Siudak, Agata Krawczyk-Ożóg, Iwona Twarda, Iwona Franczak, Renata Rajtar-Salwa, Stanisław Bartuś, Jacek Godlewski, Dariusz Dudek
BACKGROUND: Nicotine addiction is the strongest factor in the increase of the risk of recurrent ischaemic events. AIM: The aim of the study was to analyse the effectiveness of a smoking cessation educational programme in a population of patients hospitalised with acute myocardial infarction within the "Heart without smoke" campaign. METHODS: In this study, we included 100 consecutive patients, active smokers, hospitalised with acute myocardial infarction (STEMI or NSTEMI) at the Centre for Invasive Cardiology, Angiology, and Electrotherapy in Pinczow, Poland in the period from January to December 2015 (12 months)...
2018: Kardiologia Polska
https://www.readbyqxmd.com/read/28795884/results-of-directly-applied-activated-carbon-cloth-in-chronic-wounds-a-preliminary-study
#13
H S Scheer, M Kaiser, U Zingg
OBJECTIVE: Activated carbon (AC) has been used in wound therapy as an active substance inside dressings. Applying AC directly on a wound is a new concept. The aim of this study was to analyse the outcomes of chronic wounds which were managed with directly applied activated carbon knitted cloth (ACC, Zorflex) in Swiss patients. METHOD: A retrospective analysis of the records of all patients with chronic wounds treated with ACC between 1 October 2013 and 31 December 2015 in an outpatient wound clinic...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28714619/-intermittent-claudication-and-critical-limb-ischemia-from-diagnosis-to-management
#14
Pierre-Henri Morère
In case of atheromatous disease, the practitioner should be part of a multidisciplinary decision due to the associated comorbities. The angiologic assessment is of paramount importance in the diagnosis of peripheral artery disease even when the diagnosis seems clear. Unfortunately the patient is very often straightforward sent to radiological investigations who are faster. In all stages of peripheral artery disease, the medical treatment should be tried first except in case of critical limb ischemia where an invasive approach must be performed for revascularisation...
March 1, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28682727/bacterial-prevalence-and-antibiotic-resistance-in-clinical-isolates-of-diabetic-foot-ulcers-in-the-northeast-of-tamaulipas-mexico
#15
Mario Sánchez-Sánchez, Wendy Lizeth Cruz-Pulido, Eduardo Bladinieres-Cámara, Rodrigo Alcalá-Durán, Gildardo Rivera-Sánchez, Virgilio Bocanegra-García
Diabetic foot ulcers (DFUs) are a serious and common problem in patients with diabetes mellitus and constitute one of the major causes of lower extremity amputation. The microbiological profile of DFUs depends on the acute or chronic character of the wound. Aerobic gram-positive cocci are the predominant organisms isolated from DFUs. Diabetic foot biopsies from patients admitted to the Angiology and Vascular Surgery Hospital of the Northeast, in Reynosa, Tamaulipas from December 2011 to April 2016 were analyzed...
June 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28593338/-diagnostic-workup-and-therapy-of-acute-venous-diseases
#16
REVIEW
T Silber, K Schweinzer, A Strölin
Acute venous diseases, especially deep leg and pelvic vein thrombosis, present an angiological emergency and can lead to acute life-threatening events such as pulmonary embolism. Long-term consequences may be postthrombotic syndromes. In addition to stroke and myocardial infarction, deep leg and pelvic vein thrombosis are one of the most common cardiovascular diseases. Early diagnosis and rapid initiation of therapy are important.
August 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28532589/erosive-pustular-dermatosis-of-the-leg-a-prospective-multicentre-observational-study-of-36-cases
#17
P Nicol, G Perceau, C Barbe, P Bernard
BACKGROUND: Erosive pustular dermatosis of the leg (EPDL) is a poorly understood entity first described by Lanigan and Cotteril in 1987. Its clinical diagnosis is based on exclusion since the physiopathology is unknown. The primary objective of this investigation was to specify the clinical aspects and outcomes in a prospective study. The secondary objectives were to describe associated diseases, the circumstances of occurrence, and the laboratory tests used. PATIENTS AND METHODS: This was a prospective study that included 45 patients selected by members of the Angiology-Dermatology Group of the SFD (French Dermatology Society) at 13 centres between 01/09/2013 and 31/10/2014...
October 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28516250/-choosing-wisely-recommendations-in-angiology
#18
O J Müller, R Sternitzky
BACKGROUND: The Choosing wisely initiative addresses measures of high medical impact which are frequently not appropriately performed according to expert opinion. OBJECTIVE: To increase the quality of indications by providing supportive information on diagnostic and therapeutic measures in the field of angiology. MATERIALS AND METHODS: As part of the Choosing wisely initiative, the German Society of Angiology has constructed five positive recommendations on underused measures and five negative recommendations concerning those possibly overused...
June 2017: Der Internist
https://www.readbyqxmd.com/read/28514385/-the-effects-of-diosmin-and-hesperidin-on-capillary-blood-flow-of-upper-limbs-in-patients-with-secondary-raynaud-s-syndrome
#19
A M Zudin, A G Gritsenko, I T Hadzhishvili
The article discusses the effects of diosmin and hesperidin on capillary blood flow in patients with secondary Raynaud's syndrome (RS). Raynaud's syndrome a difficult problem of modern angiology, since in its development there is a large range of disorders of the capillary blood flow of the limbs. Currently, the main way of therapy in patients with secondary Raynaud's syndrome is the use of either calcium channel blockers (if angiospastic stage of the disease), or prostaglandins of group E1 (with tropho-paralytic stage of secondary RS)...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28490974/the-introduction-of-biosimilars-of-low-molecular-weight-heparins-in-europe-a-critical-review-and-reappraisal-endorsed-by-the-italian-society-for-haemostasis-and-thrombosis-siset-and-the-italian-society-for-angiology-and-vascular-medicine-siapav
#20
REVIEW
Davide Imberti, Marco Marietta, Hernan Polo Friz, Claudio Cimminiello
Recently, the European Medicines Agency (EMA) authorized the introduction and marketing of Thorinane® and Inhixa®, biosimilars of the Low Molecular Weight Heparin (LMWH) enoxaparin. The authorization path is considerably different from the guidelines published by the EMA in 2009, as well as from the recommendations from the International Society on Thrombosis and Haemostasis published in 2013. Indeed, both of them recommended that LMWHs biosimilars therapeutic equivalence should be demonstrated in at least one adequately designed clinical trial...
2017: Thrombosis Journal
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