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Fractures

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https://www.readbyqxmd.com/read/28239825/upregulated-serum-sclerostin-level-in-the-t2dm-patients-with-femur-fracture-inhibits-the-expression-of-bone-formation-remodeling-associated-biomarkers-via-antagonizing-wnt-signaling
#1
Y Wu, S-Y Xu, S-Y Liu, L Xu, S-Y Deng, Y-B He, S-C Xian, Y-H Liu, G-X Ni
OBJECTIVE: Bone formation/remodeling-associated biomarkers, such as osteocalcin, amino pro-peptide of type 1 collagen (P1NP) and CrossLaps (CTX) have been deregulated in type 2 diabetes mellitus (T2DM) patients. In particular, the T2DM-associated sclerostin markedly inhibits the bone formation, suppresses the osteoblast activity and downregulates the bone turnover. PATIENTS AND METHODS: In the present study, we examined the serum levels of sclerostin, osteocalcin, P1NP and CTX in the T2DM patients...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28238963/surgical-repair-of-massive-rotator-cuff-tendon-tears-autologous-quadriceps-tendon-graft-versus-arthroscopic-repair
#2
C Tempelaere, P Desmoineaux, F Lespagnol, J Pierrart, P Beaufils, N Pujol
INTRODUCTION: Massive rotator cuff tear repair results are variable. The main purpose of this study was to compare functional outcome between two procedures: open repair by autologous quadriceps-patella tendon patch, and arthroscopic suture. The study hypothesis was that there is no significant difference in results between the two techniques. MATERIAL AND METHODS: A retrospective study included all patients younger than 70 years operated on from 1995 to 2013 for massive rotator cuff tear...
February 23, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28238921/geometric-alteration-of-renal-arteries-after-fenestrated-grafting-and-the-impact-on-renal-function
#3
Jiale Ou, Yiu-Che Chan, Crystal Yin-Tung Chan, Stephen W K Cheng
OBJECTIVE: This study aims to investigate the degree of geometric change on renal arteries and its impact on renal function after fenestrated endovascular aortic repair (fEVAR). METHODS: Twenty-five patients with fEVAR were included. There were 47 renal arteries target vessels and 43 of these (22 left and 21 right vessels) stented successfully. Their preoperative and first postoperative follow-up computed tomography (CT) images were reconstructed using the Aquarius workstation (TeraRecon, San Mateo, CA, USA)...
February 24, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28238673/bisphosphonate-use-after-hip-fracture-in-older-adults-a%C3%A2-nationwide-retrospective-cohort-study
#4
Peter Nordström, Annika Toots, Yngve Gustafson, Karl-Göran Thorngren, Ami Hommel, Anna Nordström
OBJECTIVES: The aim of this study was to investigate the association between bisphosphonate use and the risk of new fracture in a nationwide cohort of individuals with previous hip fractures, with emphasis on individuals above 80 years of age. DESIGN, SETTING, AND PARTICIPANTS: From a nationwide cohort with hip fracture (2006-2012) (n = 93, 601), each individual prescribed bisphosphonates after hip fracture (n = 5845) was matched with up to three individuals not prescribed bisphosphonates, resulting in a cohort of 21,363 individuals...
February 23, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28238606/comparison-of-associations-of-dxa-and-ct-visceral-adipose-tissue-measures-with-insulin-resistance-lipid-levels-and-inflammatory-markers
#5
John T Schousboe, Lisa Langsetmo, Ann V Schwartz, Brent C Taylor, Tien N Vo, Allyson M Kats, Elizabeth Barrett-Connor, Eric S Orwoll, Lynn M Marshall, Iva Miljkovic, Nancy E Lane, Kristine E Ensrud
Visceral adipose tissue (VAT) measured by computed tomography (CT) is related to insulin resistance, lipids, and serum inflammatory markers. Our objective was to compare the strength of the associations of VAT measured using dual-energy X-ray absorptiometry (DXA-VAT) and CT (CT-VAT) with insulin resistance, serum lipids, and serum markers of inflammation. For 1117 men aged 65 and older enrolled in the Osteoporotic Fractures in Men Study, the cross-sectional associations of DXA-VAT and CT-VAT with homeostasis model assessment of insulin resistance (homa2ir), C-reactive protein, and high-density lipoprotein (HDL) cholesterol were estimated with regression models and compared using a Hausman test...
February 23, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28238366/modeling-potential-occupational-inhalation-exposures-and-associated-risks-of-toxic-organics-from-chemical-storage-tanks-used-in-hydraulic-fracturing-using-aermod
#6
Huan Chen, Kimberly E Carter
Various toxic chemicals used in hydraulic fracturing fluids may influence the inherent health risks associated with these operations. This study investigated the possible occupational inhalation exposures and potential risks related to the volatile organic compounds (VOCs) from chemical storage tanks and flowback pits used in hydraulic fracturing. Potential risks were evaluated based on radial distances between 5 m and 180 m from the wells for 23 contaminants with known inhalation reference concentration (RfC) or inhalation unit risks (IUR)...
February 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28238301/the-impact-of-hemocoagulase-for-improvement-of-coagulation-and-reduction-of-bleeding-in-fracture-related-hip-hemiarthroplasty-geriatric-patients-a-prospective-single-blinded-randomized-controlled-study
#7
Meiguang Qiu, Xuming Zhang, Hongru Cai, Zhixian Xu, Hao Lin
BACKGROUND: Uncontrolled bleeding is associated with poor outcomes and mortality in geriatric patients undergoing hemiarthroplasty. Hemocoagulase agkistrodon is a hemocoagulative, anti-hemorrhagic enzyme complex from Deinagkistrodon acutus snake venom. This study aimed to investigate the efficacy of hemocoagulase agkistrodon on coagulation and bleeding outcomes in fracture-related hemiarthroplasty. PATIENTS AND METHODS: This was a prospective, single-blinded, randomized controlled trial carried out between October 2013 and September 2014 in 96 geriatric patients undergoing hemiarthroplasty for unilateral femoral neck fracture...
November 27, 2016: Injury
https://www.readbyqxmd.com/read/28238222/calcium-and-phosphorus-supplementation-of-human-milk-for-preterm-infants
#8
REVIEW
Jane E Harding, Jess Wilson, Julie Brown
BACKGROUND: Preterm infants are born with low skeletal stores of calcium and phosphorus. Preterm human milk provides insufficient calcium and phosphorus to meet the estimated needs of preterm infants for adequate growth. Supplementation of human milk with calcium and phosphorus may improve growth and development of preterm infants. OBJECTIVES: To determine whether addition of calcium and phosphorus supplements to human milk leads to improved growth and bone metabolism of preterm infants without significant adverse effects...
February 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28238199/increased-number-of-community-living-older-adults-attending-an-emergency-department-with-falls-and-fractures-north-dublin-experience
#9
C W Fan, J Duggan, D Rodger, E Brazil, F McCarthy
BACKGROUND: The number of attendances to emergency department (ED) due to falls and fractures increases as the population ages. The community-based falls prevention strategy may reduce the number of falls requiring medical attention. AIM: Our aim was to determine the changes over time in community-living older adults on the number of attendances to an urban ED over a 5 year period. METHODS: Community-living adults aged ≥65 years from a catchment attending with falls and fractures to an ED in 2010 and 2014 were identified through an electronic patient record...
February 25, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28238043/cementless-and-locked-prosthesis-for-the-treatment-of-3-part-and-4-part-proximal-humerus-fractures-prospective-clinical-evaluation-of-hemi-and-reverse-arthroplasty
#10
E Boyer, G Menu, F Loisel, R Saadnia, J Uhring, A Adam, S Rochet, P Clappaz, E Baudouin, T Lascar, R Cermeno, L Obert
INTRODUCTION: Cemented stem remains the gold standard for prosthesis in trauma. The purpose of this study was to evaluate the functional and radiological outcomes of a cementless, trauma-specific locked stem (hemi and reverse) for 3- and 4-part proximal humeral fractures. MATERIALS AND METHODS: One hundred and thirty-four 3- and 4-part fractures have been treated by locked stem, 69 with hemiarthroplasty [mean age 68 years (50-90)] and 65 with reversed [mean age 78 years (66-91)]...
February 25, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28238018/the-iliotibial-tract-imaging-anatomy-injuries-and-other-pathology
#11
REVIEW
Russell Flato, Giovanni J Passanante, Matthew R Skalski, Dakshesh B Patel, Eric A White, George R Matcuk
The iliotibial tract, also known as Maissiat's band or the iliotibial band, and its associated muscles function to extend, abduct, and laterally rotate the hip, as well as aid in the stabilization of the knee. A select group of associated injuries and pathologies of the iliotibial tract are seen as sequela of repetitive stress and direct trauma. This article intends to educate the radiologist, orthopedist, and other clinicians about iliotibial tract anatomy and function and the clinical presentation, pathophysiology, and imaging findings of associated pathologies...
February 25, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28238012/two-revision-surgeries-on-cemented-custom-made-tumor-prostheses
#12
Yukihiro Yoshida, Yuki Okamura, Mamoru Akita, Masashi Taniguchi, Toshio Kojima, Eiji Osaka, Yasuaki Tokuhashi
We performed revision surgery in 2 patients for stem fracture of a cemented tumor prosthesis that occurred more than 25 years after the initial surgery. For revision, the global modular replacement system (GMRS) was used. However, as bone cement in the bone could not be adequately removed, stems with respective diameters of 11 and 12.5 mm were used. In revision surgery for cemented tumor prostheses, adequate removal of residual bone cement is optimal. However, when there is a risk of fracture, it may be appropriate to insert a thicker stem after reaming the femoral canal as much as possible, and then fix the stem using the cement-in-cement method...
February 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28237620/the-national-hip-fracture-database-nhfd-using-a-national-clinical-audit-to-raise-standards-of-nursing-care
#13
EDITORIAL
Antony Johansen, Christopher Boulton, Karen Hertz, Michael Ellis, Vivienne Burgon, Sunil Rai, Rob Wakeman
The National Hip Fracture Database (NHFD) is a key clinical governance programme for staff working in trauma wards across England, Wales and Northern Ireland. It uses prospectively collected information about the 65,000 people who present with hip fracture each year, and links these with information about the quality of care and outcome for each individual. The NHFD can, therefore, provide a picture of the care offered to frail older people with this injury - people who, between them, occupy nearly half of inpatient trauma beds...
January 23, 2017: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/28237567/low-cost-intra-articular-distraction-technique-using-kirschner-wires-and-a-toothed-lamina-spreader
#14
Stephen Joseph Shymon, Thomas Gregory Harris
We describe a low-cost (instrument cost) technique for joint distraction using 2 Kirschner wires and a toothed lamina spreader in lieu of a Hintermann distractor. The described technique allows for temporary intra-articular distraction and visualization and preservation of the articular surface with extra-articular instrumentation. The technique can also allow for closed reduction and percutaneous treatment in cases of soft tissue compromise. Additionally, the technique uses common orthopedic surgical instruments, leading to a minimal learning curve for novice surgeons...
February 22, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28237218/stereotactic-ablative-body-radiotherapy-for-the-treatment-of-spinal-oligometastases
#15
J H Chang, S Gandhidasan, R Finnigan, D Whalley, R Nair, A Herschtal, T Eade, A Kneebone, J Ruben, M Foote, S Siva
AIMS: To report multicentre outcomes of patients with spinal oligometastases treated with stereotactic ablative body radiotherapy (SABR). The primary objective was to estimate the widespread failure-free survival (WFFS) at 2 years - defined as freedom from metastases not amenable to local salvage therapy and death. MATERIALS AND METHODS: Patients with one to three metastases treated with spinal SABR between January 2010 and July 2014 at four academic institutions were included in this retrospective review...
February 22, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28236870/neuraxial-anesthesia-after-local-anesthesia-for-management-of-percutaneous-vertebroplasty-complication-during-vertebroplasty
#16
Hüseyin Balkarlı, Mesut Kılıç, İbrahim Öztürk
Percutaneous vertebroplasty is a relatively safe, simple and commonly performed interventional procedure for the management of vertebral compression fractures. However, serious complications are rarely reported in the procedure. Those are pulmonary embolism, severe infection, paraplegia and an occurrence of a new fracture in an adjacent vertebra after vertebroplasty. Acute complications are generally associated with the procedure. We present the case of neuraxial anesthesia, developed after local anesthesia with 8mL of 2% prilocaine, in a 68-year-old woman who underwent percutaneous vertebroplasty after an osteoporotic collapsed fracture in the L1 vertebra due to trauma...
March 2017: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/28236695/investigation-of-the-elastic-modulus-tensile-and-flexural-strength-of-five-skull-simulant-materials-for-impact-testing-of-a-forensic-skin-skull-brain-model
#17
Lisa Falland-Cheung, J Neil Waddell, Kai Chun Li, Darryl Tong, Paul Brunton
Conducting in vitro research for forensic, impact and injury simulation modelling generally involves the use of a skull simulant with mechanical properties similar to those found in the human skull. For this study epoxy resin, fibre filled epoxy resin, 3D-printing filaments (PETG, PLA) and self-cure acrylic denture base resin were used to fabricate the specimens (n=20 per material group), according to ISO 527-2 IBB and ISO20795-1. Tensile and flexural testing in a universal testing machine was used to measure their tensile/flexural elastic modulus and strength...
February 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28236610/zopiclone-use-and-risk-of-fractures-in-older-people-population-based-study
#18
Prasad S Nishtala, Te-Yuan Chyou
OBJECTIVES: The primary objective was to evaluate the risk of fractures associated with use of zopiclone, a new Z-hypnotic, in a population-based cohort of older people in New Zealand (NZ) in a real-world setting. The secondary objective was to examine a nonlinear relationship with age and risk for fractures in zopiclone users. DESIGN: Population-based cohort study with a case-crossover design. SETTING: A nationwide representative sample of New Zealanders aged 65 years and older sourced from the pharmaceutical collections and hospital discharges...
February 21, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28236603/computational-modelling-of-bone-fracture-healing-under-partial-weight-bearing-exercise
#19
Lihai Zhang, Saeed Miramini, Martin Richardson, Peter Ebeling, David Little, Yi Yang, Zhiyong Huang
A great deal of evidence suggests that partial weight-bearing exercise plays an important role in bone fracture healing. However, current physiotherapy program tends to follow the "Let's try it and see" strategy due to the lack of a fundamental understanding of in vivo mechanical environment required for the better healing outcomes. The purpose of present study is to develop an innovative framework to predict the healing outcomes as a result of post-surgical physical therapy. The raw acceleration data corresponding to a series of walking tests is firstly captured by ActiGraph accelerometers, and then used as input to theoretically estimate the peak ground reaction force (PGRF) and peak loading rate (PLR)...
February 21, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28236552/postoperative-impact-of-diabetes-chronic-kidney-disease-hemodialysis-and-renal-transplant-after-total-hip-arthroplasty
#20
Beau J Kildow, Perez Agaba, Brian F Moore, Rhett K Hallows, Michael P Bolognesi, Thorsten M Seyler
BACKGROUND: The prevalence of diabetes mellitus (DM), chronic kidney disease (CKD), hemodialysis (HD), and renal transplantation (RT) is increasing. This study assessed postoperative complications among diabetic patients with CKD, HD, or post-RT after total hip arthroplasty (THA). METHODS: Four cohorts were created using a nationwide database: DM&THA, DM&CKD&THA, DM&HD&THA, and DM&RT&THA. Cohorts were matched to a control group by age and gender. Thirty-day medical complications and 90-day and 2-year surgical complications were evaluated...
January 21, 2017: Journal of Arthroplasty
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