keyword
MENU ▼
Read by QxMD icon Read
search

Artery

keyword
https://www.readbyqxmd.com/read/28945061/a-comparative-study-of-cfd-of-canine-model-of-common-carotid-fusiform-aneurysm-and-vertebrobasilar-fusiform-aneurysm-in-human-patients
#1
Shewei Guo, Peng Jiang, Jian Liu, Xinjian Yang, Chuhan Jiang, Youxiang Li, Zhongxue Wu
BACKGROUND: Intracranial fusiform aneurysm (IFA) is a relatively uncommon subgroup of aneurysms. There are few reports that focus on the hemodynamics of IFA. In this study, we compared the hemodynamics of the canine model of common carotid fusiform aneurysm and vertebrobasilar fusiform aneurysms in human patients. METHODS: Five male mongrel dogs were randomly chosen, and there unilateral common carotid artery (CCA) and external jugular vein were surgically exposed individually...
September 22, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28944999/systemic-redistribution-of-the-intramyocardially-injected-mesenchymal-stem-cells-by-repeated-remote-ischaemic-post-conditioning
#2
Qin Jiang, Tao Yu, Keli Huang, Hao Zhang, Zhe Zheng, Shengshou Hu
We investigated the effect of repeated remote ischaemic post-conditioning (RIPoC) on the organ distribution of the intramyocardially injected MSCs in rat myocardial ischemia model. Myocardial ischemia of adult female Sprague-Dawley rats was induced by 30-min. obstruction of the left anterior descending coronary artery. Repeated RIPoC was induced after ischemia with three cycles of 5-min. occlusion and reperfusion of the limb with the frequency of half a day, 1 or 2 days, respectively. Compared with that by single RIPoC, repeated RIPoC transiently reduced oxidative stress, lipid peroxidation and inflammation in ischaemic myocardium; the gene expression of stromal cell-derived factor-1 alpha (SDF-1α) was consistently induced by repeated RIPoC procedures...
September 25, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28944992/ginsenoside-rb1-enhances-atherosclerotic-plaque-stability-by-skewing-macrophages-to-the-m2-phenotype
#3
Xue Zhang, Ming-Hao Liu, Lei Qiao, Xin-Yu Zhang, Xiao-Ling Liu, Mei Dong, Hong-Yan Dai, Mei Ni, Xiao-Rong Luan, Jun Guan, Hui-Xia Lu
Atherosclerosis (AS) is characterized as progressive arterial plaque, which is easy to rupture under low stability. Macrophage polarization and inflammation response plays an important role in regulating plaque stability. Ginsenoside Rb1 (Rb1), one of the main active principles of Panax Ginseng, has been found powerful potential in alleviating inflammatory response. However, whether Rb1 could exert protective effects on AS plaque stability remains unclear. This study investigated the role of Rb1 on macrophage polarization and atherosclerotic plaque stability using primary peritoneal macrophages isolated from C57BL/6 mice and AS model in ApoE(-/-) mice...
September 25, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28944947/posttraumatic-cerebral-infarction-after-decompressive-craniectomy-for-traumatic-brain-injury-incidence-risk-factors-and-outcome
#4
Tsung-Ming Su, Chu-Mei Lan, Tsung-Han Lee, Fu-Yuan Shih, Shih-Wei Hsu, Cheng-Hsien Lu
AIM: To investigate the incidence, timing, risk factors of posttraumatic cerebral infarction (PTCI) and its influence on mortality in patients with moderate to severe traumatic brain injury (TBI). MATERIAL AND METHODS: After reviewing the medical records and radiographs over a 6-year period, 173 patients with moderate to severe TBI were enrolled to determine the risk factors for the development of PTCI following unilateral decompressive craniectomy (DC). RESULTS: The incidence of PTCI following DC was 31...
July 23, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28944942/paramedian-forehead-flap-for-repair-of-refractory-high-flow-anterior-skull-base-csf-leak
#5
Jeremy Ciporen, Brandon Lucke-Wold, Haley Gillham, David Cua, Jason Kim, Paul Akins
AIM: The paramedian forehead flap (PMFF) has been well described for nasal reconstruction. However, it has never been reported for use in the repair of high flow anterior skull base cerebral spinal fluid (CSF) leaks. MATERIAL AND METHODS: The patient is a 55 yo African American male cocaine abuser who initially presented with a high flow anterior skull base CSF leak, extensive pneumocephalus, and intra-cerebral and intra-ventricular abscesses with an oro-nasal-cerebral fistula...
July 11, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28944940/ruptured-distal-accessory-anterior-cerebral-artery-aneurysm-a-case-report-and-literature-review
#6
Alperen Sirin, Ulas Cikla, Kutluay Uluc, Mustafa Kemal Baskaya
Aneurysms of the distal anterior cerebral artery (dACA) are rare, consisting only 2-6% of all intracranial aneurysms. dACA aneurysms are often associated with anomalies such as azygous, bihemispheric and triplication of ACA. Among these anomalies accessory anterior cerebral artery (accACA) is an anatomical variant found in 3.3% to 15% of the population. Here we report a case of a 60-year-old female who presented with a Hunt and Hess grade II, Fisher grade III subarachnoid hemorrhage secondary to a ruptured saccular aneurysm originating from the pericallosal-callosomarginal artery bifurcation at the A3 segment of the accessory ACA and underwent an uncomplicated microsurgical clipping...
July 12, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28944915/neuroprotective-effect-of-total-flavonoids-from-ilex-pubescens-against-focal-cerebral-ischemia-reperfusion-injury-in-rats
#7
Xiaoyan Fang, Yujie Li, Jingyi Qiao, Ying Guo, Mingsan Miao
Ilex pubescens is commonly used in traditional Chinese medicine to treat cardiovascular and cerebrovascular diseases, such as coronary artery disease and stroke. However, the underlying mechanisms remain to be fully elucidated. The aim of the present study was to investigate the effects of Ilex pubescens total flavonoids (IPTF) on neuroprotection and the potential mechanisms in a rat model of focal cerebral ischemia/reperfusion (I/R) injury. Rats were pretreated with intragastric administration of IPTF at doses of 200 and 100 mg/kg for 5 days; middle cerebral artery occlusion surgery was then performed to induce cerebral I/R injury...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944913/oleanolic-acid-alleviates-diabetic-rat-carotid-artery-injury-through-the-inhibition-of-nlrp3-inflammasome-signaling-pathways
#8
Qian An, Qian Hu, Bing Wang, Wenjun Cui, Fei Wu, Yu Ding
The overexpression of inflammasome components is correlated with diabetes‑associated complications. Oleanolic acid is a triterpenoid compound which is important in arterial injury. The present study evaluated whether oleanolic acid improved diabetic rat carotid artery injury through the inhibition of nucleotide‑binding domain, leucine‑rich‑containing family, pyrin domain‑containing‑3 (NLRP3) inflammasomes signaling pathways. A diabetic rat model was induced using streptozotocin (60 mg/kg) and underwent carotid artery injury...
September 25, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944912/dhhp%C3%A2-6-attenuates-cerebral-ischemia%C3%A2-reperfusion-injury-in-rats-through-the-inhibition-of-apoptosis
#9
Yingshi Ji, Xin Yan, Yang Hu, Huan Xue, Jianfeng Sun, Huaqiu Chen, Jiayu Zhang, Liping Wang, Baigong Xue, Li Sun
As a novel reactive oxygen species (ROS) scavenger, deuterohemin His peptide‑6 (DhHP‑6) has been demonstrated to prolong the lifespan of Caenorhabditis elegans and has also exhibited protective effects in myocardial ischemia‑reperfusion injury. Whether similar effects occur during cerebral ischemia‑reperfusion (CIR) injury remains to be elucidated. The present study evaluated the function of DhHP‑6 and its underlying mechanisms in a middle cerebral artery occlusion (MCAO) model in rats. The focal transient MCAO model was implemented using the Longa method of ischemia for 2 h followed by reperfusion for 22 h in male Wistar rats...
September 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944878/gene-expression-analysis-regulation-of-key-genes-associated-with-mycophenolate-mofetil-treatment-of-symptomatic-carotid-artery-stenosis
#10
Feng Jin, Kai Wang, Xiaochuan Sun, Zhanpu Zhang, Ping Han
The present study analyzed gene expression arrays to identify differentially-expressed genes (DEGs) between mycophenolate mofetil (MMF)‑treated and placebo‑treated patients with symptomatic carotid artery stenosis (SCAS). In addition, the key genes involved in the pharmacology of MMF treatment in patients with SCAS were identified. The gene expression dataset was obtained from a Gene Expression Omnibus database, which included 9 MMF‑treated and 11 placebo‑treated samples. The DEGs were identified between MMF and placebo groups using R software...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944871/shear-stress-induces-human-aortic-endothelial-cell-apoptosis-via-interleukin%C3%A2-1-receptor%C3%A2-associated-kinase-2%C3%A2-induced-endoplasmic-reticulum-stress
#11
Longfei Pan, Zhou Hong, Lei Yu, Yanxia Gao, Rui Zhang, Hui Feng, Lijuan Su, Gang Wang
Atherosclerosis is characterized by localized lesions distributed in the arterial tree due to the shear stress produced by blood flow. Endothelial cells are directly affected by alterations in blood flow. Dysfunction and injury to endothelial cells has been hypothesized to initiate the pathological processes of atherosclerosis. The present study aimed to investigate the mechanism of shear stress‑induced endothelial cellular apoptosis. Shear stress was generated using an artificial device to mimic the impact of disturbed blood flow on cultured human aortic endothelial cells (HAECs)...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944854/effect-of-hippocampal-l%C3%A2-nbp-on-bdnf-and-trkb-expression-and-neurological-function-of-vascular-dementia-rats
#12
Yujing Huang, Zhaohui Li, Guangxian Nan
The pathogenesis of vascular dementia (VD) is associated with neuronal degeneration, apoptosis or necrosis following ischemic brain injury. L‑butylphthalide (L‑NBP), has been demonstrated to exhibit potent anti‑ischemic and anti‑VD effects, however the associated specific mechanism remains to be elucidated. The present study generated a VD rat model, in which the effect of L‑NBP on neurological function and expression levels of brain‑derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (TrkB) were observed...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944828/protective-effects-of-gv1001-on-myocardial-ischemia%C3%A2-reperfusion-injury
#13
Ji-Eun Chang, Hyun Jun Kim, Sanghoon Jheon, Cheong Lim
The potential cardioprotective effects of the novel vaccine peptide GV1001 were evaluated in myocardial ischemia‑reperfusion injury induced rat models. GV1001 is a human telomerase reverse transcriptase derived peptide, which has been reported to possess both anti‑tumor and anti‑inflammatory effects. The normal saline (control group) and various concentrations (0.001‑10 mg/kg) of GV1001 were administered directly to the right ventricle anterior wall before induction of ischemia. The was induced by Tightening the snare around the left anterior descending coronary artery for 40 min, before releasing the snare for 10 min induced the myocardial ischemia‑reperfusion injury and was conducted in Sprague‑Dawley rats...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944827/cerebral-ischemia-reperfusion-injury-induces-airway-mucus-hypersecretion-in-rats-and-activates-il%C3%A2-13%C3%A2-associated-inflammatory-mechanisms
#14
Baoning Xu, Lei Zhang, Yuqin Che, Chengyang Song, Wenjun Jiang, Jianhua Fan, Dali Tian
The majority of patients that suffer a stroke have excessive sputum, which accelerates the development of pulmonary complications. However, it is unclear whether cerebral ischemia and reperfusion (I/R) injury induces mucus hypersecretion, and the potential role of inflammation remains unknown. In the present study, the reversible middle cerebral artery occlusion model was applied in rats to induce cerebral I/R injury. The rats were grouped according to the duration of reperfusion (6, 12, 24, 48 and 72 h). Neurological dysfunction was evaluated by Longa scoring and lung dry‑to‑wet weight (dw/ww) ratios were determined to reflect the degree of mucus secretion...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944741/the-application-of-nanoparticles-for-neuroprotection-in-acute-ischemic-stroke
#15
Lepei Chen, Xiaoling Gao
Stroke still represents one of the most common causes of death and disability worldwide. Acute ischemic stroke (AIS), caused by brain arterial occlusion resulting from a thrombus or embolus, is the most common form of stroke. However, current therapies in AIS are inadequate, and the only US FDA approved treatment is the thrombolytic drug Alteplase. Therefore, establishing effective therapeutic strategies for AIS is urgently needed. Using nanoparticle-based technologies to deliver neuroprotective agents to the ischemic area has attracted increasing attention of late...
October 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28944708/partial-thrombosis-of-an-anterior-communicating-artery-aneurysm-prior-to-endovascular-coiling-with-intra-procedural-distal-thrombus-embolization
#16
Will Guest, Dipanka Sarma, Thomas Marotta
Thromboembolic stroke from migration of thrombus formed in non-giant intracranial aneurysms is a recognized but rare event. We describe a case of partial thrombosis of a 7 mm anterior communicating artery aneurysm, which embolized to the right callosomarginal artery in the brief time interval between two sequential diagnostic angiograms performed as part of elective endovascular coiling, and before any instrumentation had been advanced into the intracranial circulation. To our knowledge, this is the first reported case of aneurysmal thrombus embolization observed angiographically in near real time...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28944705/influence-of-carotid-tortuosity-on-internal-carotid-artery-access-time-in-the-treatment-of-acute-ischemic-stroke
#17
Z O Kaymaz, O Nikoubashman, M A Brockmann, M Wiesmann, C Brockmann
Purpose Carotid artery anatomy is thought to influence internal carotid artery access time (ICA-AT) in patients requiring mechanical thrombectomy for acute ischemic stroke. This study investigates the association between ICA-AT and carotid anatomy. Material and methods Computed tomography angiography (CTA) data of 76 consecutive patients presenting with acute ischemic stroke requiring mechanical thrombectomy for middle cerebral artery or carotid T occlusion were evaluated. The supraaortic extracranial vasculature was analyzed regarding take-off angles and curvature of the affected side...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28944620/intracoronary-snaring-of-the-retrograde-guidewire-how-to-overcome-extreme-takeoff-angles-in-chronic-total-occlusion-percutaneous-coronary-intervention
#18
Lorenzo Azzalini, Luciano Candilio, Mauro Carlino, Antonio Colombo
Extreme angulation of coronary artery takeoff represents a challenge for wiring and device advancement in percutaneous coronary intervention (PCI). This anatomic feature is particularly adverse in cases of chronic total occlusion (CTO) of the ostial-proximal segment of the target vessel. In this setting, the retrograde approach can help getting access to the occlusion. However, difficulties might arise at the critical step of wire externalization, due to the need to overcome the extreme ostial angle. Here, we describe a case of successful CTO PCI of the proximal circumflex artery, which presented an extreme angle at its takeoff...
September 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28944581/a-new-one-step-procedure-for-pulmonary-valve-implantation-of-the-melody-valve-simultaneous-prestenting-and-valve-implantation
#19
Younes Boudjemline
OBJECTIVES: To describe a new modification, the one-step procedure, that allows interventionists to pre-stent and implant a Melody valve simultaneously. BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) is the standard of care for managing patients with dysfunctional right ventricular outflow tract, and the approach is standardized. METHODS: Patients undergoing PPVI using the one-step procedure were identified in our database. Procedural data and radiation exposure were compared to those in a matched group of patients who underwent PPVI using the conventional two-step procedure...
September 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28944572/sizing-of-patent-ductus-arteriosus-in-adults-for-transcatheter-closure-using-the-balloon-pull-through-technique
#20
Nabil A Shafi, Gagan D Singh, Thomas W Smith, Jason H Rogers
OBJECTIVES: To describe a novel balloon sizing technique used during adult transcatheter patent ductus arteriosus (PDA) closure. In addition, to determine the clinical and procedural outcomes in six patients who underwent PDA balloon sizing with subsequent deployment of a PDA occluder device. BACKGROUND: Transcatheter PDA closure in adults has excellent safety and procedural outcomes. However, PDA sizing in adults can be challenging due to variable defect size, high flow state, or anatomical complexity...
September 25, 2017: Catheterization and Cardiovascular Interventions
keyword
keyword
13330
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"