keyword
https://read.qxmd.com/read/38530345/vitamin-d-deficiency-and-its-association-with-vitamin-d-receptor-gene-variants-among-malaysian-women-with-hypertensive-disorders-in-pregnancy-protocol-for-a-nutrigenomics-study
#1
JOURNAL ARTICLE
Yakubu Ibrahim, Nurul Iftida, Norshariza Nordin, Amilia Afzan Mohd Jamil
BACKGROUND: Vitamin D deficiency has been associated with hypertensive disorders in pregnancy (HDP). The risk of developing HDP was reported to be further augmented among individuals with a vitamin D receptor (VDR) genetic variant. However, the reported roles of VDR variants in hypertensive disorders are inconsistent among different populations. Given the relatively higher incidence of vitamin D deficiency among Malaysian pregnant women and the high incidence of HDP in this population, we hypothesize that there may be associations between the risk of vitamin D deficiency and HDP with VDR genetic variants...
March 26, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38494687/vitamin-d-nutritional-status-in-early-pregnancy-and-its-relationship-with-periconceptional-multiple-micronutrients-supplementation
#2
JOURNAL ARTICLE
Chun-Jing Wang, Zhao Li, Yin-Xiao Bai, Wen-Ying Meng, Chun-Yi Liu, Lei Jin, Jie Zhang, Ming-Yuan Jiao, Lei Jin
BACKGROUND AND OBJECTIVES: To assess the vitamin D nutritional status (VDN) of pregnant women in early pregnancy and investigate the effects of periconceptional supplementation with multiple micronutrients (MMs) on this status. METHODS AND STUDY DESIGN: Data were taken from the Pregnancy Health Care System and Hospital Information System in 2018 in Beijing. Vitamin D nutritional status in early pregnancy was evaluated among 4,978 pregnant women, and 4,540 women who took folic acid only (FA) or multiple mi-cronutrients supplements (MM) during the periconceptional period, were include to estimate the associations between periconceptional supplementation with MM and prevalence of vitamin D deficiency or insufficiency with logistic regression model...
March 2024: Asia Pacific Journal of Clinical Nutrition
https://read.qxmd.com/read/38461819/the-influence-of-vitamin-d-on-pregnancy-and-outcomes-current-knowledge-and-future-perspectives
#3
Zhanar Kurmangali, Bibigul Abdykalykova, Aimen Kurmangali, Danat Zhantagulov, Milan Terzic
Vitamin D deficiency increases the risk of adverse pregnancy outcomes. The high prevalence of vitamin D deficiency worldwide requires the analysis of scientific publications to make recommendations for the prevention, management and treatment of vitamin D deficiency in pregnant women. The purpose of the research was to explore the relationship between pathology and pregnancy outcomes with serum 25-hydroxycholecalciferol levels and vitamin D supplementation. A literature search was performed for systematic literature reviews with meta-analyses published between January 2018 and February 2023...
March 8, 2024: Gynecologic and Obstetric Investigation
https://read.qxmd.com/read/38461776/effect-modification-by-maternal-vitamin-d-status-in-the-association-between-prenatal-exposure-to-per-and-polyfluoroalkyl-substances-and-neurodevelopment-in-2-year-old-children
#4
JOURNAL ARTICLE
Yu Gao, Yan Zhang, Jiajun Luo, Dandan Mao, Xiaoning Lei, Chong Liu, Shanyu Zhang, Qian Yao, Jiong Li, Jun Zhang, Xiaodan Yu, Ying Tian
BACKGROUND: Pregnant women in the Shanghai Birth Cohort (SBC) of China faced dual threats of per- and polyfluoroalkyl substances (PFAS) exposure and vitamin D (VD) insufficiency, potentially impacting offspring neurodevelopment. However, little is known about whether maternal VD status modifies PFAS-related neurodevelopment effect. OBJECTIVES: To explore the modifying role of maternal VD status in the effect of prenatal PFAS exposure on childhood neurodevelopment...
March 5, 2024: Environment International
https://read.qxmd.com/read/38442813/trimester-specific-effect-of-maternal-co-exposure-to-organophosphate-esters-and-phthalates-on-preschooler-cognitive-development-the-moderating-role-of-gestational-vitamin-d-status
#5
JOURNAL ARTICLE
Mengjuan Lu, Gan Hong, Qiong Zhou, Feifei Han, Xiaorui Wang, Fu Zhang, Juan Tong, Kun Huang, Hui Gao, Shuangqin Yan, Zhongxiu Jin, Qunan Wang, Fangbiao Tao
Organophosphate esters (OPEs) and phthalate acid esters (PAEs) are prevalent endocrine-disrupting chemicals (EDCs). Humans are often exposed to OPEs and PAEs simultaneously through multiple routes. Given that fetal stage is a critical period for neurodevelopment, it is necessary to know whether gestational co-exposure to OPEs and PAEs affects fetal neurodevelopment. However, accessible epidemiological studies are limited. The present study included 2, 120 pregnant women from the Ma'anshan Birth Cohort (MABC) study...
March 3, 2024: Environmental Research
https://read.qxmd.com/read/38432714/the-effects-of-prenatal-and-postnatal-high-dose-vitamin-b-12-supplementation-on-human-milk-vitamin-b-12-a-randomized-double-blind-placebo-controlled-trial-in-tanzania
#6
JOURNAL ARTICLE
Dongqing Wang, Setareh Shahab-Ferdows, Omar N Lweno, Daniela Hampel, Balama Method, Cara A Yelverton, Christine H Nguyen, Said Aboud, Lindsay H Allen, Wafaie W Fawzi
BACKGROUND: Vitamin B-12 status in human milk (HM) has critical implications for infant growth and development. Few studies have separately evaluated the effects of prenatal and postnatal maternal high-dose vitamin B-12 supplementation on HM vitamin B-12 concentration. OBJECTIVES: This randomized controlled trial aimed to assess the effects of prenatal and postnatal vitamin B-12 supplementation on HM vitamin B-12 at 6 wk and 7 mo postpartum. METHODS: Pregnant women were enrolled in Dar es Salaam, Tanzania, between 2001 and 2004...
March 2024: American Journal of Clinical Nutrition
https://read.qxmd.com/read/38422005/vitamin-d-levels-of-pregnant-immigrant-women-and-developmental-disorders-of-language-learning-and-coordination-in-offspring
#7
JOURNAL ARTICLE
Bianca Arrhenius, Heljä-Marja Surcel, Susanna Hinkka Yli-Salomäki, Alan Brown, Keely Cheslack-Postava, Andre Sourander
BACKGROUND: Prenatal vitamin D deficiency is a common health concern among immigrants. No previous studies have examined the associations between prenatal vitamin D levels and developmental disorders of language, scholastic skills, and coordination in an immigrant sample. METHODS: The sample included 542 immigrant mothers of cases with language, scholastic, coordination or mixed developmental disorders, 443 immigrant mothers of controls without these disorders and 542 Finnish mothers of controls...
2024: PloS One
https://read.qxmd.com/read/38421481/reference-gene-validation-in-the-embryonic-and-postnatal-brain-in-the-rat-hyperhomocysteinemia-model
#8
JOURNAL ARTICLE
Anna A Kovalenko, Alexander P Schwarz, Anastasiia D Shcherbitskaia, Anastasiia V Mikhel, Dmitrii S Vasilev, Alexander V Arutjunyan
Maternal hyperhomocysteinemia (HCY) induced by genetic defects in methionine cycle enzymes or vitamin imbalance is known to be a pathologic factor that can impair embryonal brain development and cause long-term consequences in the postnatal brain development as well as changes in the expression of neuronal genes. Studies of the gene expression on this model requires the selection of optimal housekeeping genes. This work aimed to analyze the expression stability of housekeeping genes in offspring brain. Pregnant female Wistar rats were treated daily with a 0...
February 29, 2024: Neurotoxicity Research
https://read.qxmd.com/read/38418231/effects-of-vitamin-d-levels-during-pregnancy-on-prematurity-a-systematic-review-protocol
#9
JOURNAL ARTICLE
Olívia Barbosa, Margarida Sim-Sim, Marta Pereira Silvestre, Cristina Pedro, Dulce Cruz
INTRODUCTION: Prematurity is an urgent public health problem worldwide. Recent studies associate maternal hypovitaminosis D during pregnancy with an increased risk of prematurity. However, the evidence on this association remains inconclusive, and there is lack of consensus in the literature. The exact mechanism by which low vitamin D levels may increase the risk of preterm birth is not yet fully understood. Nevertheless, it is known that vitamin D may play a role in maintaining a healthy pregnancy by regulating inflammation and immunomodulation by acting on the maternal and fetal immune systems...
February 28, 2024: BMJ Open
https://read.qxmd.com/read/38413986/improvements-in-lung-function-following-vitamin-c-supplementation-to-pregnant-smokers-are-associated-with-buccal-dna-methylation-at-5-years-of-age
#10
JOURNAL ARTICLE
Lyndsey E Shorey-Kendrick, Cindy T McEvoy, Kristin Milner, Julia Harris, Julie Brownsberger, Robert S Tepper, Byung Park, Lina Gao, Annette Vu, Cynthia D Morris, Eliot R Spindel
BACKGROUND: We previously reported in the "Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function" randomized clinical trial (RCT) that vitamin C (500 mg/day) supplementation to pregnant smokers is associated with improved respiratory outcomes that persist through 5 years of age. The objective of this study was to assess whether buccal cell DNA methylation (DNAm), as a surrogate for airway epithelium, is associated with vitamin C supplementation, improved lung function, and decreased occurrence of wheeze...
February 27, 2024: Clinical Epigenetics
https://read.qxmd.com/read/38408566/an-8-week-vitamin-d3-fortified-fruit-drink-supplementation-increases-serum-ferritin-concentration-a-randomized-controlled-trial-in-malaysian-women-with-low-iron-stores
#11
JOURNAL ARTICLE
Nursyafiqah Aqilah Suhaimi, Loh Su Peng, Norhafizah Ab Manan, Nurzalinda Zalbahar, Muhammad Najib Mohamad Alwi, Salma Faeza Ahmad Fuzi
BACKGROUND: Limited randomized controlled trial (RCT) evidence supports the association between vitamin D deficiency and anemia risk, highlighting the necessity for further investigations into the role of vitamin D in influencing iron status OBJECTIVE/DESIGN: An 8-week double-blind RCT was carried out to determine the effect of vitamin D3-fortified fruit drink consumption (4000 IU) on vitamin D and iron status biomarkers among iron-deficient women (serum ferritin of <20 μg/L) SUBJECTS/SETTING: A total of 45 healthy, non-pregnant/lactating subjects aged 18-40 years [mean (SD): 25...
February 24, 2024: Journal of the Academy of Nutrition and Dietetics
https://read.qxmd.com/read/38407272/short-communications-one-carbon-metabolite-supplementation-to-nutrient-restricted-beef-heifers-affects-placental-vascularity-during-early-pregnancy
#12
JOURNAL ARTICLE
Chutikun Kanjanaruch, Kerri A Bochantin, Bethania J Dávila Ruiz, Jessica Syring, Yssi Entzie, Layla King, Pawel P Borowicz, Matthew S Crouse, Joel S Caton, Carl R Dahlen, Alison K Ward, Lawrence P Reynolds
We hypothesized that restricted maternal nutrition and supplementation of one-carbon metabolites (OCM; methionine, folate, choline, and vitamin B12) would affect placental vascular development during early pregnancy. A total of 43 cows were bred, and 32 heifers successfully became pregnant with female calves, leading to the formation of four treatment groups: CON - OCM (n=8), CON + OCM (n=7), RES - OCM (n=9), and RES + OCM (n=8). The experimental design was a 2 × 2 factorial, with main factors of dietary intake affecting average daily gain: control (CON; 0...
February 26, 2024: Journal of Animal Science
https://read.qxmd.com/read/38391407/are-maternal-vitamin-d-25-oh-d-levels-a-predisposing-risk-factor-for-neonatal-growth-a-cross-sectional-study
#13
JOURNAL ARTICLE
Artemisia Kokkinari, Maria Dagla, Evangelia Antoniou, Aikaterini Lykeridou, Georgios Iatrakis
BACKGROUND: Neonatal bone mass may potentially be influenced by existing maternal vitamin D (25(OH)D) levels. Few studies evaluated maternal vitamin D deficiency (VDD) with neonatal anthropometrics such as weight, height and head circumference (HC), especially in Greece, which is a Mediterranean country with plenty of sunshine and consequently benefits the synthesis of 25(OH)D. We investigated this potential association in Greece, taking into account the administration or not of prenatal vitamin D supplements...
February 5, 2024: Clinics and Practice
https://read.qxmd.com/read/38379394/biomarkers-associated-with-cardiovascular-disease-in-women-with-spontaneous-preterm-birth-a-case-control-study
#14
JOURNAL ARTICLE
Elin Täufer Cederlöf, Susanne Lager, Anders Larsson, Inger Sundström Poromaa, Bertil Lindahl, Anna-Karin Wikström, Christina Christersson
INTRODUCTION: Women with spontaneous preterm birth have an increased risk of cardiovascular disease later in life. Studies suggest potential pathophysiological mechanisms in common, but whether these could be identified by measurement of soluble circulating protein biomarkers in women with spontaneous preterm birth is unknown. The aim of this study was to determine if protein biomarkers associated with cardiovascular disease distinguish women with spontaneous preterm birth from healthy controls, both at pregnancy and at follow up...
February 20, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38370042/nutritional-intake-and-determinants-of-nutritional-quality-changes-from-pregnancy-to-postpartum-a-longitudinal-study
#15
JOURNAL ARTICLE
Mathilda Forsby, Erik Hulander, Anna Amberntsson, Petra Brembeck, Anna Winkvist, Linnea Bärebring, Hanna Augustin
Nutrient requirements vary across the reproductive cycle, but research on changes in nutritional intake and quality from pregnancy to beyond the lactation period is limited. Thus, we aimed to study nutritional intake and quality changes, among Swedish pregnant participants from late pregnancy to 18 months postpartum and to study the determinants of nutritional quality changes. Participants ( n  = 72) were studied longitudinally from the third trimester of pregnancy and postpartum (2 weeks 4, 12, and 18 months postpartum)...
February 2024: Food Science & Nutrition
https://read.qxmd.com/read/38368233/a-review-of-dairy-food-intake-for-improving-health-for-black-women-in-the-us-during-pregnancy-fetal-development-and-lactation
#16
JOURNAL ARTICLE
Yolanda Lawson, Kevin B Comerford, Edith P Mitchell
Pregnancy and lactation are special life stages that require regular nutritional and medical attention to help protect the health of the mother and promote the growth and development of the offspring. Despite an increased focus on maternal and fetal health over the last several decades, the rates of pregnancy-related morbidity and mortality are increasing in the United States (US). On average, Black women who are pregnant or lactating face greater health disparities and birth complications than other racial/ethnic groups in the US...
February 16, 2024: Journal of the National Medical Association
https://read.qxmd.com/read/38356841/the-effect-of-folic-acid-b12-d-and-e-vitamins-and-melatonin-levels-in-the-follicular-fluid-taken-by-the-intracytoplasmic-sperm-injection-method-on-pregnancy
#17
JOURNAL ARTICLE
Kenan Demir, Suleyman Tumer Caliskan, Sebahattin Celik, Muhterem Akdeniz, Rumeysa Yilmaz Goc
OBJECTIVE: It has been demonstrated that the composition of the follicular fluid and many internal/external factors affect success in subfertile couples undergoing intracytoplasmic sperm injection (ICSI). We examined the effect of folic acid, B12, D, and E vitamins and melatonin values in follicular fluid on pregnancy in women with low, normal, and high ovarian reserves who underwent ICSI. METHODS: Our study was conducted at Samsun Medical Park Hospital between January 2021 and February 2022...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38350553/microrna-125b-regulates-vitamin-d-resistance-by-targeting-cyp24a1-in-the-progression-of-gestational-diabetes-mellitus
#18
JOURNAL ARTICLE
K L Milan, Ravichandran Jayasuriya, Harithpriya Kannan, M Anuradha, Kunka Mohanram Ramkumar
Vitamin D deficiency is prevalent in pregnancy and has been associated with increased occurrences of preeclampsia, cesarean delivery, neonatal bacterial vaginosis, and gestational diabetes. CYP24A1, recognized as a key factor in vitamin D metabolism homeostasis, encodes 24-hydroxylase responsible for converting 25(OH)D3 and 1,25(OH)2D3 into inactive metabolites. Recently, we have reported CYP24A1 overexpression in patients with gestational diabetes mellitus (GDM) and trophoblast cells exposed to hyperglycemia...
February 11, 2024: Journal of Steroid Biochemistry and Molecular Biology
https://read.qxmd.com/read/38348147/pregnancy-and-lactation-related-osteoporosis-in-a-22-year-old-woman
#19
Ali Ghassa, Yara Hodifa, Qais Falhout
KEY CLINICAL MESSAGE: Any pregnant or lactating woman with severe constant back pain, PLO must be kept in mind due to its effect on the quality of life of the mother and her child. ABSTRACT: A 22-year-old woman, who delivered her first child 5 months ago and is now breastfeeding her baby, presented with mid-back pain. After investigations, including laboratory tests, X-rays, and bone density measurements, the diagnosis was PLO. The patient is being treated with calcium, vitamin D, and alendronate besides discontinuation of lactation...
February 2024: Clinical Case Reports
https://read.qxmd.com/read/38347382/mediating-effect-of-insulin-like-growth-factor-i-underlying-the-link-between-vitamin-d-and-gestational-diabetes-mellitus
#20
JOURNAL ARTICLE
Lingling Cui, Zhiqian Li, Xiaoli Yang, Huijun Zhou, Zhengya Zhang, Yuting Gao, Lina Ren, Yibo Wang, Ruijie Sun, Linpu Ji, Linlin Hua
Vitamin D was well-known to be associated with gestational diabetes mellitus (GDM). Insulin-like growth factor-I (IGF-I) has been linked to vitamin D and GDM, respectively. We hypothesize that changes in IGF-I metabolism induced by 25(OH)D3 might contribute to GDM. Therefore, we investigated the independent and combined relationships of serum 25(OH)D3 and IGF-I concentrations with GDM risk, and the mediation effect of IGF-I on 25(OH)D3 . A total of 278 pregnant women (including 125 cases and 153 controls) were recruited in our current study...
February 12, 2024: Reproductive Sciences
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