keyword
MENU ▼
Read by QxMD icon Read
search

Radiation therapy

keyword
https://www.readbyqxmd.com/read/29356235/contribution-of-intraoperative-radiotherapy-iort-for-therapeutic-de-escalation-in-early-breast-cancer-report-of-a-single-institution-s-experience
#1
Julien Barrou, Agnes Tallet, Monique Cohen, Marie Bannier, Max Buttarelli, Laurence Gonzague, Camille Jauffret, Eric Lambaudie, Sandrine Rua, Margueritte Tyran, Leonel Varela, Gilles Houvenaeghel
The spread of systematic screening and the emergence of oncoplastic techniques allow more breast conservative treatment associating lumpectomy and external beam radiation therapy. In order to furthermore facilitate the patient's treatment, intraoperative radiation therapy (IORT) has been developed. The oncological safety of this technique has been studied, and is considered acceptable. Many questions remain unsolved in regard of the toxicity of this procedure as well as the patient's selection criteria. In this study, we present the first results and complications rate of patients treated by IORT in a single French institution...
January 22, 2018: Breast Journal
https://www.readbyqxmd.com/read/29355969/primary-liver-sarcomas-in-the-modern-era-resection-or-transplantation
#2
Ioannis T Konstantinidis, Carolijn Nota, Zeljka Jutric, Philip Ituarte, Warren Chow, Peiguo Chu, Gagandeep Singh, Susanne G Warner, Laleh G Melstrom, Yuman Fong
BACKGROUND AND OBJECTIVES: Primary liver sarcomas (PLS) are rare. Published series are limited by small numbers of patients. METHODS: We reviewed the National Cancer Database (2004-2014) for patients who underwent surgical resection of PLS. RESULTS: Of 237 patients identified, the majority were female (60.8%), with median age of 52 years. Histologies were: epithelioid hemangioendothelioma (n = 67), angiosarcoma (n = 64), leiomyosarcoma (n = 33), embryonal rhabdomyosarcoma (n = 31), carcinosarcoma (n = 16), giant cell sarcoma (n = 14), spindle cell sarcoma (n = 12)...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355797/cyberknife-radiosurgery-in-the-multimodal-management-of-patients-with-cushing-s-disease
#3
Justin M Moore, Elisa Sala, Alvaro Amorin, Hector Martinez, Aprotim C Bhowmik, Steven D Chang, Scott G Soltys, Griffith R Harsh, Laurence Katznelson
OBJECTIVE: Surgery is the primary treatment for Cushing's disease (CD). However, when surgery is not successful at normalizing hypercortisolism, adjuvant radiation, such as stereotactic radiosurgery (SRS), may be useful to improving biochemical control. METHODS: We completed a retrospectively cohort study of consecutively treated patients with CyberKnife (CK) radiosurgery for active CD at Stanford Hospital and Clinics. RESULTS: As first line treatment, all patients underwent transsphenoidal surgery with histological demonstration of an adrenocorticotropic hormone (ACTH) producing pituitary adenoma...
January 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29355615/a-competing-risk-model-of-first-failure-site-after-definitive-chemo-radiation-therapy-for-locally-advanced-non-small-cell-lung-cancer
#4
Lotte Nygård, Ivan R Vogelius, Barbara M Fischer, Andreas Kjær, Seppo W Langer, Marianne Aznar, Gitte F Persson, Søren M Bentzen
INTRODUCTION: The aim of the study was to build a model of first failure site and lesion specific failure probability after definitive chemo-radiotherapy for inoperable non-small cell lung cancer (NSCLC). METHODS: We retrospectively analyzed 251 patients receiving definitive chemo/radiotherapy for NSCLC at a single institution between 2009-2015. All patients were FDG PET/CT scanned for radiotherapy planning. Clinical patient data and FDG PET standardized uptake values from primary tumor and nodal lesions were analyzed using multivariate cause-specific Cox regression...
January 18, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29354876/evaluating-treatment-patterns-for-small-cell-carcinoma-of-the-colon-using-the-national-cancer-database-ncdb
#5
Sadhana Balasubramanyam, Barrett P O'Donnell, Benjamin L Musher, Pavan M Jhaveri, Michelle S Ludwig
OBJECTIVE(S): The objective of this study was to characterize the clinicopathological prognostic factors and treatment patterns for small cell carcinoma (SCC) of the colon, a rare disease without standard treatment guidelines. METHODS: We analyzed clinicopathological and treatment variables for 503 cases of histologically proven SCC colon entered into the National Cancer Database (NCDB) between 2004 and 2013. Survival curves were generated using Kaplan-Meier and compared by the log-rank test...
January 22, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29354756/multifocal-intradural-extramedullary-anaplastic-ependymoma-of-the-spine
#6
Ananya Chakravorty, Ellen Frydenberg, Tint Tint Shein, John Ly, Peter Earls, Timothy Steel
Ependymomas are neuroectodermal tumours arising from the ependymal lining of the ventricles and central canal of the spinal cord. Intradural extramedullary (IDEM) ependymomas which are multifocal, and/or anaplastic (WHO grade III) at presentation are exceedingly rare. We present the second case of multifocal anaplastic IDEM ependymoma in the literature. A 47-year old female presented with left gluteal and thigh pain radiating to the groin associated with paraesthesiae. She had a normal neurological examination...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29354587/botulinum-toxin-type-a-injection-for-neuropathic-pain-in-a-patient-with-a-brain-tumor-a-case-report
#7
Kyung Eun Nam, Joon Sung Kim, Bo Young Hong, Bomi Sul, Hyehoon Choi, So Yeon Jun, Seong Hoon Lim
Neuropathic pain is usually managed pharmacologically, rather than with botulinum toxin type A (BTX-A). However, medications commonly fail to relieve pain effectively or have intolerable side effects. We present the case of a 62-year-old man diagnosed with an intracranial chondrosarcoma, which was removed surgically and treated with radiation therapy. He suffered from neuropathic pain despite combined pharmacological therapy with gabapentin, amitriptyline, tramadol, diazepam, and duloxetine because of adverse effects...
December 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29354390/radiotherapy-and-glioma-stem-cells-searching-for-chinks-in-cellular-armor
#8
Seamus P Caragher, Sean Sachdev, Atique Ahmed
Purpose of the review: Radiation became a pillar of oncologic treatment in the last century and provided a powerful and effective locoregional treatment of solid malignancies. After achieving some of the first cures in lymphomas and skin cancers, it assumed a key role in curative treatment of epithelioid malignancies. Despite success across a variety of histologic types, glioblastoma (GBM), the most common primary brain tumor afflicting adults, remains ultimately resistant to current radiation strategies...
December 2017: Current Stem Cell Reports
https://www.readbyqxmd.com/read/29354236/gamma-knife-radiosurgery-for-cancer-metastasized-to-the-ocular-choroid
#9
Kyung Rae Cho, Kyung Min Lee, Gyule Han, Se Woong Kang, Jung-Il Lee
Objective: Choroidal metastases (CMs) are the most common intraocular tumor. Management is mainly radiation therapy with goals of pain control and visual improvement. However, many radiation-related complications are reported. Since gamma knife radiosurgery (GKS) for CM was first reported in 1995, few cases have been reported. We report 7 cases of CMs treated with GKS. Methods: From April 2011 to November 2014, 7 patients with CM underwent GKS. Their median age at treatment was 64 years (range, 51-71 years)...
January 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29353840/-7-radiation-therapy-for-prostate-cancer
#10
Tomohiko Tanino, Nobue Uchida
No abstract text is available yet for this article.
2018: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/29353699/near-infrared-heat-lamp-therapeutic-effect-on-paraoxonase-1-and-myeloperoxidase-as-potential-biomarkers-of-redox-state-changes-induced-by-%C3%AE-irradiation-in-albino-rats
#11
N Abdel-Magied, A G Ahmed, S M Shedid
Infrared radiation has a potential therapeutic effect in some diseases. The aim of this study was to estimate the therapeutic role of near infrared heat lamp (NIRHL) on the variations of the activity of paraoxonase 1 (PON1) and myeloperoxidase (MPO), in relation to lipid disorders, associated with oxidative stress in rats gamma-irradiated. In addition, study the effect of the duration of NIRHL treatment. Animals were divided into six groups. The results revealed that irradiated rats treated with NIRHL 20 min/once/day showed positive modulation of PON1 and MPO linked to significant improvement of lipid disorders evidenced by lower triglycerides, low density lipoprotein cholesterol (LDL-C), oxidized low density lipoprotein cholesterol (oxLDL-C) and higher density lipoprotein cholesterol (HDL-C) as well as significant amelioration of redox state, manifested by markedly increase of glutathione (GSH) content, total antioxidant capacity (TAC) associated with a noticeable decrease of pro-inflammatory cytokines...
January 16, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29353666/erratum-to-hafeez-s-mcdonald-f-lalondrelle-s-et-al-clinical-outcomes-of-image-guided-adaptive-hypofractionated-weekly-radiation-therapy-for-bladder-cancer-in-patients-unsuitable-for-radical-treatment-int-j-radiat-oncol-biol-phys-2017-98-115-122
#12
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353665/erratum-to-wang-sy-kelly-g-gross-c-et%C3%A2-al-information-needs-of-older-women-with-early-stage-breast-cancer-when-making-radiation-therapy-decisions-int-j-radiat-oncol-biol-phys-2017-98-733-740
#13
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353660/intraoperative-electron-radiation-therapy-in%C3%A2-retroperitoneal-sarcoma
#14
Falk Roeder, Ingo Alldinger, Matthias Uhl, Ladan Saleh-Ebrahimi, Simon Schimmack, Gunhild Mechtersheimer, Markus W Büchler, Jürgen Debus, Robert Krempien, Alexis Ulrich
PURPOSE: To report our experience with surgery, intraoperative radiation therapy (IORT), and external beam radiation therapy (EBRT) in retroperitoneal soft-tissue sarcoma. METHODS AND MATERIALS: We conducted a retrospective evaluation of 156 patients (69 primary, 87 recurrent) treated with IORT since 1991. The dominant histology was dedifferentiated liposarcoma (49%); 89% of lesions were high grade. Median tumor size was 11 cm. Surgery resulted in gross complete resection in 92%, and 65% had microscopically positive margins...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353659/trends-in-cardiac-mortality-in-patients-with-locally-advanced-non-small-cell-lung-cancer
#15
Waqar Haque, Vivek Verma, Mohamad Fakhreddine, E Brian Butler, Bin S Teh, Charles B Simone
PURPOSE: To use the Surveillance, Epidemiology, and End Results (SEER) database to compare cardiac-specific mortality (CSM) between left- and right-sided locally advanced non-small cell lung cancer (LA-NSCLC) patients treated with definitive radiation therapy; and to stratify these patients over fixed time intervals to assess for differences in events by treatment era. METHODS AND MATERIALS: The SEER database was queried for patients with stage III NSCLC who received radiation therapy to compare CSM between left- and right-sided primary cases at 5 time intervals: 1988-1992, 1993-1997, 1998-2002, 2003-2007, and 2008-2012...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353658/tumor-control-and-toxicity-for-common-stereotactic-body-radiation-therapy-dose-fractionation-regimens-in-stage-i-non-small-cell-lung-cancer
#16
Kevin L Stephans, Neil M Woody, Chandana A Reddy, Matthew Varley, Anthony Magnelli, Tingliang Zhuang, Peng Qi, Gregory M M Videtic
PURPOSE: To examine the impact of stereotactic body radiation therapy (SBRT) dose on outcomes in early-stage non-small cell lung cancer in a large single-institution series. METHODS AND MATERIALS: We reviewed 600 patients treated from 2003 to 2012 for early-stage non-small cell lung cancer. The SBRT dose was at physician discretion on the basis of tumor size and location. Peripheral tumors were treated to 60 Gy in 3 fractions (homogeneous planning), 48-50 Gy in 4-5 fractions, or 30-34 Gy in 1 fraction...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353656/systematic-review-of-normal-tissue-complication-models-relevant-to-standard-fractionation-radiation-therapy-of-the-head-and-neck-region-published-after-the-quantec-reports
#17
REVIEW
N Patrik Brodin, Rafi Kabarriti, Madhur K Garg, Chandan Guha, Wolfgang A Tomé
There has recently been an increasing interest in model-based evaluation and comparison of different treatment options in radiation oncology studies. This is partly driven by the considerable technical advancements in radiation therapy of the last decade, leaving radiation oncologists with a multitude of options to consider. In lieu of randomized trials comparing all of these different treatment options for varying indications, which is unfeasible, treatment evaluations based on normal tissue complication probability (NTCP) models offer a practical alternative...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353655/cost-effectiveness-of-primary-radiation-therapy-versus-radical-prostatectomy-for-intermediate-to-high-risk-prostate-cancer
#18
Jennifer A Dorth, W Robert Lee, Junzo Chino, Robert Abouassaly, Rodney J Ellis, Evan R Myers
PURPOSE: To compare, using a cost-effectiveness analysis, the quality-adjusted life expectancy (QALE) and cost between the 2 treatment options for intermediate- to high-risk prostate cancer: (1) radiation (RT) with androgen deprivation therapy (ADT) or (2) radical prostatectomy (RP) followed by adjuvant RT for patients with risk factors. METHODS AND MATERIALS: Our Markov model allowed patients to transition between health states with yearly probabilities of developing cancer recurrence and/or toxicity...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353654/magnetic-resonance-imaging-guided-adaptive-radiation-therapy-a-game-changer-for-prostate-treatment
#19
REVIEW
Angela U Pathmanathan, Nicholas J van As, Linda G W Kerkmeijer, John Christodouleas, Colleen A F Lawton, Danny Vesprini, Uulke A van der Heide, Steven J Frank, Simeon Nill, Uwe Oelfke, Marcel van Herk, X Allen Li, Kathryn Mittauer, Mark Ritter, Ananya Choudhury, Alison C Tree
Radiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator allows for accurate soft tissue tracking with the capacity to replan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MRI-only workflow, and real-time adaptive planning...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29353652/modeling-of-normal-tissue-complications-using-imaging-and-biomarkers-after-radiation-therapy-for-hepatocellular-carcinoma
#20
Issam El Naqa, Adam Johansson, Dawn Owen, Kyle Cuneo, Yue Cao, Martha Matuszak, Latifa Bazzi, Theodore S Lawrence, Randall K Ten Haken
PURPOSE: To develop normal tissue complications (NTCP) models for hepatocellular cancer (HCC) patients who undergo liver radiation therapy (RT) and to evaluate the potential role of functional imaging and measurement of blood-based circulating biological markers before and during RT to improve the performance of these models. METHODS AND MATERIALS: The data from 192 HCC patients who had undergone RT from 2005 to 2014 were evaluated. Of the 192 patients, 146 had received stereotactic body RT (SBRT) and 46 had received conventional RT to a median physical tumor dose of 49...
February 1, 2018: International Journal of Radiation Oncology, Biology, Physics
keyword
keyword
13302
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"