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https://www.readbyqxmd.com/read/29150985/general-illness-and-psychological-factors-in-patients-with-chronic-nasal-symptoms
#1
Naveed Kara, Alexander C Yao, Julia Newton, Vincent Deary, James O'Hara, Janet A Wilson
OBJECTIVES: Only a minority of patients referred to specialists with sinonasal symptoms have clear evidence of chronic rhinosinusitis. This study aims to estimate the prevalence of and associations between (i) general illness factors (fatigue, autonomic dysfunction) and (ii) psychological factors (anxiety, depression, somatisation, personality traits) in patients presenting with sinonasal symptoms. DESIGN: The following validated questionnaires were administered to patients: the Sino-Nasal Outcome Test-22 (SNOT-22) to identify symptom burden, Composite Autonomic Symptom Score-31 (COMPASS-31) measuring autonomic function, Chalder fatigue questionnaire, Patient Health Questionnaire-15 (PHQ-15) addressing somatisation symptoms, Hospital Anxiety and Depression Scale (HADS), and the International Personality Item Pool-50 (IPIP-50)...
November 18, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29149520/compassion-in-practice-evaluating-the-awareness-involvement-and-perceived-impact-of-a-national-nursing-and-midwifery-strategy-amongst-health-care-professionals-in-nhs-trusts-in-england
#2
Helen Allan, Mike O'Driscoll, Liang Liu, Kevin Corbett, Laura Serrant
AIM: To report the findings from an evaluation of the impact of the Compassion in Practice Vision & Strategy (CiPVS) (National Health Service England (NHSE), 2012) on nursing, midwifery and care staff. BACKGROUND: The CiPVS was a programme of work to highlight the importance of compassionate care following the Francis Report in 2013 into the deficits in care in an NHS hospital trust. It was launched by NHS England in 2012 at a time when fiscal cuts were introduced by the Department of Health in England...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29144981/barriers-to-self-compassion-for-female-survivors-of-childhood-maltreatment-the-roles-of-fear-of-self-compassion-and-psychological-inflexibility
#3
Derrecka M Boykin, Sara J Himmerich, Caitlin M Pinciotti, Lindsay M Miller, Lynsey R Miron, Holly K Orcutt
Preliminary evidence has demonstrated the benefits of targeting self-compassion in the treatment of posttraumatic stress disorder (PTSD). However, survivors of childhood maltreatment may present with unique challenges that compromise the effectiveness of these and other PTSD treatments. Specifically, childhood maltreatment victims often exhibit a marked fear and active resistance of self-kindness and warmth (i.e., fear of self-compassion). Victims may also attempt to control distressing internal experiences in a way that hinders engagement in value-based actions (i...
November 13, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29144881/improving-graduation-rates-for-african-americans-in-drug-court-importance-of-human-relationships-and-barriers-to-gaining-and-sustaining-employment
#4
John Robert Gallagher, Anne Nordberg, Alyssa R Dibley
Drug courts have been an important part of the criminal justice system since 1989. They continue to expand throughout the United States because nearly three decades of research has shown that they are more effective than other interventions, such as traditional probation. There is a pattern, though, in some drug courts where African Americans are less likely to graduate than their Caucasian counterparts. This qualitative study explores this phenomenon by asking African American participants (n = 31) their views on the most helpful aspects of drug court and how drug court could be more helpful in supporting them in graduating the program...
November 16, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29138278/a-cytoplasmic-compass-is-necessary-for-cell-survival-and-triple-negative-breast-cancer-pathogenesis-by-regulating-metabolism
#5
Lu Wang, Clayton K Collings, Zibo Zhao, Kira Alia Cozzolino, Quanhong Ma, Kaiwei Liang, Stacy A Marshall, Christie C Sze, Rintaro Hashizume, Jeffrey Nicholas Savas, Ali Shilatifard
Mutations and translocations within the COMPASS (complex of proteins associated with Set1) family of histone lysine methyltransferases are associated with a large number of human diseases, including cancer. Here we report that SET1B/COMPASS, which is essential for cell survival, surprisingly has a cytoplasmic variant. SET1B, but not its SET domain, is critical for maintaining cell viability, indicating a novel catalytic-independent role of SET1B/COMPASS. Loss of SET1B or its unique cytoplasmic-interacting protein, BOD1, leads to up-regulation of expression of numerous genes modulating fatty acid metabolism, including ADIPOR1 (adiponectin receptor 1), COX7C, SDC4, and COQ7 Our detailed molecular studies identify ADIPOR1 signaling, which is inactivated in both obesity and human cancers, as a key target of SET1B/COMPASS...
November 14, 2017: Genes & Development
https://www.readbyqxmd.com/read/29135927/design-and-calibration-of-a-novel-bio-inspired-pixelated-polarized-light-compass
#6
Guoliang Han, Xiaoping Hu, Junxiang Lian, Xiaofeng He, Lilian Zhang, Yujie Wang, Fengliang Dong
Animals, such as Savannah sparrows and North American monarch butterflies, are able to obtain compass information from skylight polarization patterns to help them navigate effectively and robustly. Inspired by excellent navigation ability of animals, this paper proposes a novel image-based polarized light compass, which has the advantages of having a small size and being light weight. Firstly, the polarized light compass, which is composed of a Charge Coupled Device (CCD) camera, a pixelated polarizer array and a wide-angle lens, is introduced...
November 14, 2017: Sensors
https://www.readbyqxmd.com/read/29133680/nurturing-neurosurgery-with-basics-and-compassion-%C3%A2-some-thoughts
#7
Subhash R Dharker
No abstract text is available yet for this article.
November 2017: Neurology India
https://www.readbyqxmd.com/read/29132880/rivaroxaban-with-or-without-aspirin-in-patients-with-stable-peripheral-or-carotid-artery-disease-an-international-randomised-double-blind-placebo-controlled-trial
#8
Sonia S Anand, Jackie Bosch, John W Eikelboom, Stuart J Connolly, Rafael Diaz, Peter Widimsky, Victor Aboyans, Marco Alings, Ajay K Kakkar, Katalin Keltai, Aldo P Maggioni, Basil S Lewis, Stefan Störk, Jun Zhu, Patricio Lopez-Jaramillo, Martin O'Donnell, Patrick J Commerford, Dragos Vinereanu, Nana Pogosova, Lars Ryden, Keith A A Fox, Deepak L Bhatt, Frank Misselwitz, John D Varigos, Thomas Vanassche, Alvaro A Avezum, Edmond Chen, Kelley Branch, Darryl P Leong, Shrikant I Bangdiwala, Robert G Hart, Salim Yusuf
BACKGROUND: Patients with peripheral artery disease have an increased risk of cardiovascular morbidity and mortality. Antiplatelet agents are widely used to reduce these complications. METHODS: This was a multicentre, double-blind, randomised placebo-controlled trial for which patients were recruited at 602 hospitals, clinics, or community practices from 33 countries across six continents. Eligible patients had a history of peripheral artery disease of the lower extremities (previous peripheral bypass surgery or angioplasty, limb or foot amputation, intermittent claudication with objective evidence of peripheral artery disease), of the carotid arteries (previous carotid artery revascularisation or asymptomatic carotid artery stenosis of at least 50%), or coronary artery disease with an ankle-brachial index of less than 0·90...
November 10, 2017: Lancet
https://www.readbyqxmd.com/read/29132879/rivaroxaban-with-or-without-aspirin-in-patients-with-stable-coronary-artery-disease-an-international-randomised-double-blind-placebo-controlled-trial
#9
Stuart J Connolly, John W Eikelboom, Jackie Bosch, Gilles Dagenais, Leanne Dyal, Fernando Lanas, Kaj Metsarinne, Martin O'Donnell, Anthony L Dans, Jong-Won Ha, Alexandr N Parkhomenko, Alvaro A Avezum, Eva Lonn, Liu Lisheng, Christian Torp-Pedersen, Petr Widimsky, Aldo P Maggioni, Camilo Felix, Katalin Keltai, Masatsugu Hori, Khalid Yusoff, Tomasz J Guzik, Deepak L Bhatt, Kelley R H Branch, Nancy Cook Bruns, Scott D Berkowitz, Sonia S Anand, John D Varigos, Keith A A Fox, Salim Yusuf
BACKGROUND: Coronary artery disease is a major cause of morbidity and mortality worldwide, and is a consequence of acute thrombotic events involving activation of platelets and coagulation proteins. Factor Xa inhibitors and aspirin each reduce thrombotic events but have not yet been tested in combination or against each other in patients with stable coronary artery disease. METHODS: In this multicentre, double-blind, randomised, placebo-controlled, outpatient trial, patients with stable coronary artery disease or peripheral artery disease were recruited at 602 hospitals, clinics, or community centres in 33 countries...
November 10, 2017: Lancet
https://www.readbyqxmd.com/read/29132286/the-gendered-experiences-of-children-in-child-headed-households-in-swaziland
#10
Nozipho Mkhatshwa
This study investigated the gender dynamics of living in child-headed households (CHHs) in a rural area in Swaziland that experiences high levels of drought, poverty and HIV and AIDS. Using a qualitative research methodology, the study examined ways in which children in CHHs meet their daily family needs and address their vulnerabilities according to their gender, focusing on the experiences of the children. The study sample consisted of 10 households, with 5 boy and 5 girl-headed households from the chiefdoms within the area...
December 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/29131716/compassion-focused-therapy-as-an-intervention-for-adult-survivors-of-sexual-abuse
#11
Lisa McLean, Stanley R Steindl, Matthew Bambling
Child sexual abuse can have long-term negative impacts across psychological, physical, and interpersonal domains. Some of the common issues for survivors of sexual abuse include shame and self-blame, attachment-based difficulties, avoidant coping strategies, and reduced capacity for self-compassion. Compassion-focused therapy is a transdiagnostic intervention that specifically responds to these concerns. Compassion-focused therapy was originally developed for clients who experience high levels of shame and self-criticism and aims to strengthen the soothing and affiliative system through the cultivation of compassion...
November 13, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29129740/survey-on-neonatal-end-of-life-comfort-care-guidelines-across-america
#12
Shelly Haug, Sara Farooqi, Christopher G Wilson, Andrew Hopper, Grace Oei, Brian Carter
CONTEXT: Infants of age < 1 year have the highest mortality rate in pediatrics. The American Academy of Pediatrics (AAP) published guidelines for palliative care in 2013, however, significant variation persists among local protocols addressing neonatal comfort care at the end-of-life (EOL). OBJECTIVES: The purpose of this study was to evaluate current neonatal EOL comfort care practices and clinician satisfaction across America METHODS: After Institutional Review Board approval (516005), an anonymous, electronic survey was sent to members of the AAP Section on Neonatal-Perinatal Medicine...
November 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29129639/determinants-of-histone-h3k4-methylation-patterns
#13
Luis M Soares, P Cody He, Yujin Chun, Hyunsuk Suh, TaeSoo Kim, Stephen Buratowski
Various factors differentially recognize trimethylated histone H3 lysine 4 (H3K4me3) near promoters, H3K4me2 just downstream, and promoter-distal H3K4me1 to modulate gene expression. This methylation "gradient" is thought to result from preferential binding of the H3K4 methyltransferase Set1/complex associated with Set1 (COMPASS) to promoter-proximal RNA polymerase II. However, other studies have suggested that location-specific cues allosterically activate Set1. Chromatin immunoprecipitation sequencing (ChIP-seq) experiments show that H3K4 methylation patterns on active genes are not universal or fixed and change in response to both transcription elongation rate and frequency as well as reduced COMPASS activity...
November 16, 2017: Molecular Cell
https://www.readbyqxmd.com/read/29125338/providing-high-quality-care-at-the-end-of-life-the-role-of-education-and-guidance
#14
Jill Dobson
Palliative care in the UK has been ranked as the best in the world. So where did palliative care go so wrong that a 168-page document is required to inform staff how to care for dying patients if it has been going so well for so long? Those nearing the end of their life deserve to be given optimum care, attention, compassion and consideration, but this is not always the case. The Liverpool Care Pathway was a tool originally devised to help health professionals provide high-quality end-of-life care to people in the final phase of life...
November 9, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29120304/an-examination-of-school-and-student-level-characteristics-associated-with-the-likelihood-of-students-meeting-the-canadian-physical-activity-guidelines-in-the-compass-study
#15
Amanda Harvey, Guy Faulkner, Lora Giangregorio, Scott T Leatherdale
OBJECTIVES: To examine school- and student-level correlates of physical activity. METHODS: Cross-sectional Year 2 data collected from 45 298 grade 9-12 students attending 89 secondary schools in the COMPASS study were examined using multi-level modelling to predict the likelihood of students a) achieving 60 minutes of moderate to vigorous physical activity (MVPA) daily; and b) achieving the Canadian Society for Exercise Physiology (CSEP) activity guideline for youth (60 minutes/MVPA daily, vigorous physical activity at least three days in a week, and resistance training at least three days in a week)...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29120280/self-compassion-mediates-the-relationship-between-mindfulness-and-borderline-personality-disorder-symptoms
#16
Hannah J Scheibner, Anna Daniels, Simon Guendelman, Franca Utz, Felix Bermpohl
Individuals suffering from borderline personality disorder (BPD) experience difficulties with mindfulness. How mindfulness influences BPD symptoms, however, is still unknown. We hypothesized that the relationship between mindfulness and BPD symptoms would be mediated by self-compassion. In study 1, we recruited 29 individuals with BPD and 30 group-matched healthy controls. In study 2, we complemented our results with findings from a larger, nonclinical sample of 89 participants that were recruited during an open-house event at the local university...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29120197/a-three-component-model-of-future-time-perspective-across-adulthood
#17
Margund K Rohr, Dennis T John, Helene H Fung, Frieder R Lang
Although extensive findings underscore the relevance of future time perspective (FTP) in the process of aging, the assumption of FTP as a unifactorial construct has been challenged. The present study explores the factorial structure of the FTP scale (Carstensen & Lang, 1996) as one of the most widely used measures (Ntotal = 2,170). Results support that FTP reflects a higher-order construct that consists of 3 interrelated components-Opportunity, Extension, and Constraint. It is suggested that the flexible usage of the FTP scale as an all compassing 10-item measure or with focus on specific components depends on the concrete research question...
November 2017: Psychology and Aging
https://www.readbyqxmd.com/read/29120193/feel-the-way-with-a-vibrotactile-compass-does-a-navigational-aid-aid-navigation
#18
Steven M Weisberg, Daniel Badgio, Anjan Chatterjee
Knowing where north is provides a navigator with invaluable information for learning and recalling a space, particularly in places with limited navigational cues, like complex indoor environments. Although north is effectively used by orienteers, pilots, and military personnel, very little is known about whether nonexpert populations can or will use north to create an accurate representation of an indoor space. In the current study, we taught people 2 nonoverlapping routes through a complex indoor environment, with which they were not familiar-a university hospital with few windows and several turns...
November 9, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/29119775/binge-drinking-and-academic-performance-engagement-aspirations-and-expectations-a-longitudinal-analysis-among-secondary-school-students-in-the-compass-study
#19
Karen A Patte, Wei Qian, Scott T Leatherdale
INTRODUCTION: The longitudinal relationship between binge drinking and academic engagement, performance, and future aspirations and expectations was examined among a cohort of secondary school students. METHODS: In separate multinomial generalized estimating equations models, linked data from Year 1 (Y1: 2012-2013), Year 2 (Y2: 2013-2014), and Year 3 (Y3: 2014-2015) of the COMPASS study (N = 27 112) were used to test the relative likelihood of responses to seven academic indices when binge drinking was initiated in varying frequencies, adjusting for gender, grade, race/ethnicity, tobacco use, and the individual mean of the predictor and all time-varying covariates...
November 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29119672/self-compassion-and-psychological-distress-in-parents-of-young-people-and-adults-with-intellectual-and-developmental-disabilities
#20
Suzanne Robinson, Richard P Hastings, Jonathan A Weiss, Jaffni Pagavathsing, Yona Lunsky
BACKGROUND: Parenting an individual with intellectual and developmental disabilities (IDD) can be challenging, particularly during adulthood. It is important to better understand ways of supporting families as individuals with IDD age. Self-compassion is a potential internal coping resource for parents, and is strongly linked to positive mental health outcomes, though research has yet to examine it in parents of adults with IDD. METHOD: The current study examines the association between self-compassion and measures of well-being for 56 parents of adults with IDD...
November 9, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
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