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https://www.readbyqxmd.com/read/27932267/human-pre-pik3c2b-an-intronic-cis-element-with-dual-function-of-activation-and-repression
#1
Jayant Maini, Mohsen Ghasemi, Deepti Yandhuri, Suman S Thakur, Vani Brahmachari
The Polycomb/Trithorax Responsive Elements (PRE/TREs) are the cis-regulatory sequences that interact with both repressive (PcG) as well as activating (TrxG) complexes. However, most of the mammalian PREs are demonstrated to interact with the repressive polycomb (PcG) complexes only. We have carried out an unbiased search for proteins interacting with human PRE-PIK3C2B (hPRE-PIK3C2B) based on DNA affinity purification followed by mass spectrometry and identified MLL, MLL4 and WDR87 among other proteins in three biological replicates in HEK, U87 and HeLa cell lines...
December 5, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27929700/the-mediating-effects-of-coping-strategies-on-the-relationship-between-secondary-traumatic-stress-and-burnout-in-professional-caregivers-in-the-uae
#2
Abdalla A R M Hamid, Saif A Musa
BACKGROUND: Professional caregivers dealing with traumatized victims or mental health clients are at increased risk for developing the same symptoms as persons who are exposed directly to the trauma. AIMS: This research was aimed at examining the relationship between secondary traumatic stress, burnout and coping strategies in 502 professional caregivers who work in schools, hospitals, charity institutes and welfare centers in the United Arab Emirates (UAE). A further aim was to test the mediating effect of coping on the relationship between burnout and secondary traumatic stress...
December 8, 2016: Journal of Mental Health
https://www.readbyqxmd.com/read/27929608/an-open-trial-of-mindfulness-based-stress-reduction-for-young-adults-with%C3%A2-social-anxiety-disorder
#3
Aslak Hjeltnes, Helge Molde, Elisabeth Schanche, Jon Vøllestad, Julie Lillebostad Svendsen, Christian Moltu, Per-Einar Binder
The present study investigated mindfulness-based stress reduction (MBSR) for young adults with a social anxiety disorder (SAD) in an open trial. Fifty-three young adults in a higher education setting underwent a standard eight-week MBSR program. Eight participants (15%) did not complete the program. Participants reported significant reductions in SAD symptoms and global psychological distress, as well as increases in mindfulness, self-compassion, and self-esteem. Using intention-to-treat (ITT) analyses, effect sizes ranged from large to moderate for SAD symptoms (Cohen's d = 0...
December 8, 2016: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/27928859/mindfulness-interventions-for-psychosis-a-systematic-review-of-the-literature
#4
REVIEW
J Aust, T Bradshaw
: WHAT IS KNOWN ON THE SUBJECT?: Psychosis and the more specific diagnosis of schizophrenia constitute a major psychiatric disorder which impacts heavily on the self-esteem, functioning and quality of life of those affected. A number of mindfulness therapies have been developed in recent years, showing promising results when used with people with the disorder. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: This review of the literature included only randomized controlled trials (RCTs), rather than other typically less robust methods of research (e...
December 8, 2016: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/27923897/empathy-sympathy-and-compassion-in-healthcare-is-there-a-problem-is-there-a-difference-does-it-matter
#5
David Jeffrey
No abstract text is available yet for this article.
December 2016: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/27922178/lessons-from-the-homeless-civil-and-uncivil-interactions-with-nurses-self-care-behaviors-and-barriers-to-care
#6
Wendy M Woith, Cindy Kerber, Kim S Astroth, Sheryl H Jenkins
BACKGROUND: Civility, rooted in social justice, is a fundamental value of nursing. Homeless people are particularly at risk for experiencing uncivil behavior from nurses. PURPOSE: The purpose of this study was to explore homeless people's perceptions of their interactions with nurses. METHOD: In this descriptive, qualitative study, we interviewed 15 homeless adults who described their experiences with nurses. The interview guide, developed by the researchers, consisted of open-ended questions and probes...
December 6, 2016: Nursing Forum
https://www.readbyqxmd.com/read/27920946/insights-in-public-health-substance-use-in-pregnant-women-in-hawai-i-extending-our-capacity-and-compassion
#7
Rebecca Delafield, Tricia E Wright
Substance use can have serious consequences for the health and well-being of individuals. The problem is of particular concern when it involves pregnant women due to health risks for the mother and the fetus. In utero exposure to either legal (eg, alcohol, cigarettes, and certain prescription drugs) or illicit (eg, amphetamines, cocaine, and opioids) substances can result in potentially serious and long-lasting health problems for infants. Available data from Hawai'i indicate that substance use among pregnant women is higher than national targets, which reflect the fact that there is essentially no acceptable rate of use of these substances...
November 2016: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/27920736/protective-effect-of-self-compassion-to-emotional-response-among-students-with-chronic-academic-stress
#8
Yonghong Zhang, Xi Luo, Xianwei Che, Wenjie Duan
The literature has shown that self-compassion is a protective factor of an individual's emotional response to chronic stress. However, this stress-buffering effect has not been completely analyzed in individuals who report significantly high academic stress. The present study explored the role of self-compassion in a group of undergraduate students who experience chronic academic stress. A total of 208 undergraduate students who were preparing for the Postgraduate Entrance Examination (PEE) were recruited and completed the Self-Compassion Scale, Adolescent Self-Rating Life Event Check List, and Positive and Negative Affect Schedule...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27917534/a-concept-analysis-of-compassionate-midwifery
#9
Diane Ménage, Elizabeth Bailey, Susan Lees, Jane Coad
AIM: To report a concept analysis of compassionate midwifery. BACKGROUND: Recently, compassion has been incorporated into United Kingdom nursing and midwifery language through strategy, policy, recruitment and education. Professional standards direct midwives to practise compassionately therefore the concept of compassionate midwifery exists, although this has yet to be explored as a concept in the UK or internationally. An understanding of what constitutes compassionate midwifery has the potential to increase midwifery knowledge and improve practice...
November 16, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27917136/decentering-the-self-reduced-bias-in-self-vs-other-related-processing-in-long-term-practitioners-of-loving-kindness-meditation
#10
Fynn-Mathis Trautwein, José R Naranjo, Stefan Schmidt
Research in social neuroscience provides increasing evidence that self and other are interconnected, both on a conceptual and on an affective representational level. Moreover, the ability to recognize the other as "like the self" is thought to be essential for social phenomena like empathy and compassion. Meditation practices such as loving-kindness meditation (LKM) have been found to enhance these capacities. Therefore, we investigated whether LKM is associated to an increased integration of self-other-representations...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27916513/empathy-and-its-discontents
#11
REVIEW
Paul Bloom
What role does the experience of feeling what you think others are feeling - often known as 'empathy' - have in moral deliberation and moral action? Empathy has many fans and there is abundant evidence that it can motivate prosocial behavior. However, empathy is narrow in its focus, rendering it innumerate and subject to bias. It can motivate cruelty and aggression and lead to burnout and exhaustion. Compassion is distinct from empathy in its neural instantiation and its behavioral consequences and is a better prod to moral action, particularly in the modern world we live in...
December 1, 2016: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/27910584/fitting-of-the-thomson-scattering-density-and-temperature-profiles-on-the-compass-tokamak
#12
E Stefanikova, M Peterka, P Bohm, P Bilkova, M Aftanas, M Sos, J Urban, M Hron, R Panek
A new technique for fitting the full radial profiles of electron density and temperature obtained by the Thomson scattering diagnostic in H-mode discharges on the COMPASS tokamak is described. The technique combines the conventionally used modified hyperbolic tangent function for the edge transport barrier (pedestal) fitting and a modification of a Gaussian function for fitting the core plasma. Low number of parameters of this combined function and their straightforward interpretability and controllability provide a robust method for obtaining physically reasonable profile fits...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909465/group-and-individual-mindfulness-based-cognitive-therapy-mbct-are-both-effective-a-pilot-randomized-controlled-trial-in-depressed-people-with-a-somatic-disease
#13
Maya J Schroevers, K Annika Tovote, Evelien Snippe, Joke Fleer
Depressive symptoms are commonly reported by individuals suffering from a chronic medical condition. Mindfulness-based cognitive therapy (MBCT) has been shown to be an effective psychological intervention for reducing depressive symptoms in a range of populations. MBCT is traditionally given in a group format. The aim of the current pilot RCT was to examine the effects of group-based MBCT and individually based MBCT for reducing depressive symptoms in adults suffering from one or more somatic diseases. In this study, 56 people with a somatic condition and comorbid depressive symptoms (i...
2016: Mindfulness
https://www.readbyqxmd.com/read/27909464/mindfulness-and-self-compassion-as-unique-and-common-predictors-of-affect-in-the-general-population
#14
Angélica López, Robbert Sanderman, Maya J Schroevers
In contrast to the increased research interest in the benefits of mindfulness and self-compassion, relatively few studies have examined their unique and combined effects in predicting affect. This cross-sectional study examined the predictive value of mindfulness and self-compassion for depressive symptoms, negative affect, and positive affect in a large representative sample of community adults (N = 1736). The Five Facets of Mindfulness Questionnaire (FFMQ) was used as a measure of mindfulness and the Self-Compassion Scale (SCS) as a measure of self-compassion...
2016: Mindfulness
https://www.readbyqxmd.com/read/27909417/defining-contemplative-science-the-metacognitive-self-regulatory-capacity-of-the-mind-context-of-meditation-practice-and-modes-of-existential-awareness
#15
Dusana Dorjee
The term 'contemplative' is now frequently used in the fast growing field of meditation research. Yet, there is no consensus regarding the definition of contemplative science. Meditation studies commonly imply that contemplative practices such as mindfulness or compassion are the subject of contemplative science. Such approach, arguably, contributes to terminological confusions in the field, is not conducive to the development of an overarching theory in contemplative science, and overshadows its unique methodological features...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27909161/test-of-a-social-cognitive-model-of-well-being-among-breast-cancer-survivors
#16
Trisha L Raque-Bogdan, Robert W Lent, Brooke Lamphere
Given the potentially long-standing emotional impact of breast cancer, theoretical models are needed to identify critical resources and coping strategies that optimize survivors' long-term adjustment. This study tested a model of well-being recovery with breast cancer survivors at 4 years post-treatment. Structural equation modeling was used to examine relationships between affect, loneliness, self-compassion, self-efficacy for coping with cancer, well-being, and life satisfaction. Two model variations offered good fit to the data, accounting for large portions of the variance in well-being and life satisfaction...
December 1, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27903035/the-inherited-chronic-pain-patient
#17
Paul Grinzi
BACKGROUND: The 'inherited' patient, where a patient switches to a new doctor, is a common and potentially challenging scenario, especially where drugs of dependence are involved. There are few resources to guide general practitioners (GPs) with an approach that ensures compassion and rational clinical decision-making. OBJECTIVE: The aim of this article is to guide GPs in an approach to taking over the care of an inherited patient and focuses on considerations of rational prescribing...
December 2016: Australian Family Physician
https://www.readbyqxmd.com/read/27902121/celebrating-innovation
#18
Alison Whyte
'These examples of nursing innovation from all corners of Yorkshire and the Humber truly demonstrate the breadth of nursing skill, experience and leadership across the region,' says RCN Yorkshire and the Humber regional director Glenn Turp. 'They speak volumes about the commitment and compassion of nurses and their dedication to patient care.'
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27898142/sv%C3%A3-ra-samtal-med-patienter-tr%C3%A3-nas-p%C3%A3-kurs-med-sk%C3%A3-despelare-en-medveten-strategi-hj%C3%A3-lper-b%C3%A3-de-l%C3%A3-kare-och-patient
#19
Anders Danielsson, Hanna Dahlstrand, Franziska Edvinsson, Mattias Tranberg, Anna Wrangsjö, Carl-Johan Fürst
The physician's communication skill influences the patient's mental and physical wellbeing, as well as the physician's own experience of stress. Most patients wish to be informed about their disease, by physicians who are honest, gives time, sustains hope, listens and shows compassion and empathy. Even though there are established guidelines on how to break bad news, the physician must find out and respond to the unique reactions and needs of each individual, in order to communicate successfully. There is no consensus on how to construct and evaluate communication skills training programs for physicians, and more RCT-studies are requested...
November 22, 2016: Läkartidningen
https://www.readbyqxmd.com/read/27898134/quality-pain-care-for-older-adults-in-an-era-of-suspicion-and-scrutiny
#20
Barbara St Marie, Paul Arnstein
In two decades, the pendulum has swung from focusing on the undertreatment of pain by prescribers who fail to use medically necessary opioid agents to an intense focus on overprescribing opioid medications and the harms they cause. Within these two extremes rests the older adult with pain and in need of safe and effective care. Today, health care providers are practicing in an era of scrutiny, with new guidelines and regulations superseding their compassion and clinical judgment about the best treatment options when older adults have pain across the care continuum...
December 1, 2016: Journal of Gerontological Nursing
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