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https://www.readbyqxmd.com/read/28641070/elmo-proteins-transduce-g-protein-coupled-receptor-signal-to-control-reorganization-of-actin-cytoskeleton-in-chemotaxis-of-eukaryotic-cells
#1
Xuehua Xu, Tian Jin
Chemotaxis, which is chemoattractant-guided directional cell migration, plays major roles in recruitment of neutrophils, the metastasis of cancer cells, and the development of the model organism Dictyostelium discoideum. These cells share remarkable similarities in the signaling pathways by which they control chemotaxis. They all use a G protein-coupled receptor (GPCR)-mediated signal transduction pathway to sense the chemotactic gradient to guide cell migration. Diverse chemokines activate Rac through conserved GPCR signaling pathways...
June 22, 2017: Small GTPases
https://www.readbyqxmd.com/read/28635987/integrative-review-of-facility-interventions-to-manage-compassion-fatigue-in-oncology-nurses
#2
Dorien Wentzel, Petra Brysiewicz
PROBLEM IDENTIFICATION: Oncology nurses are regularly exposed to high-stress situations that may lead to compassion fatigue, and many institutions have implemented interventions to reduce burnout in nurses, but knowledge on the feasiblity, effectiveness, and nurses' experience of interventions is lacking.
. LITERATURE SEARCH: Electronic search of literature published from 1992-2015 was performed to evaluate in-facility interventions to manage compassion fatigue in oncology nurses...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28635466/a-profession-to-be-proud-of
#3
Caroline Shuldham
We have to admire the responses of individuals and organisations to the Grenfell Tower fire and the recent terrorist attacks, where major incident plans were activated. Our colleagues, nurses and the wider healthcare teams showed heroism, expertise, compassion and commitment.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28634765/a-450-year-old-turkish-poem-on-medical-ethics
#4
REVIEW
Halil Tekiner
The Ottoman physician-poet Nidai of Ankara (1509 to post-1567) studied medicine in Crimea and served as a court physician in Istanbul during the reign of Sultan Selim II. Nidai marked the classical period of Ottoman medicine particularly with his acclaimed works and translations in Turkish, among which Manafi al-Nas (Benefits of People, 1566) became widely known. The final chapter of Manafi al-Nas also is known independently under the name Vasiyyetname (Last Will), which is a remarkable guide on medical ethics...
June 20, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28633990/cellular-gauge-symmetry-and-the-li-organization-principle-a-mathematical-addendum-quantifying-energetic-dynamics-in-physical-and-biological-systems-through-a-simple-geometric-tool-and-geodetic-curves
#5
REVIEW
Alexander Yurkin, Arturo Tozzi, James F Peters, Pedro C Marijuán
The present Addendum complements the accompanying paper "Cellular Gauge Symmetry and the Li Organization Principle"; it illustrates a recently-developed geometrical physical model able to assess electronic movements and energetic paths in atomic shells. The model describes a multi-level system of circular, wavy and zigzag paths which can be projected onto a horizontal tape. This model ushers in a visual interpretation of the distribution of atomic electrons' energy levels and the corresponding quantum numbers through rather simple tools, such as compasses, rulers and straightforward calculations...
June 17, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28630895/glass-eels-anguilla-anguilla-have-a-magnetic-compass-linked-to-the-tidal-cycle
#6
Alessandro Cresci, Claire B Paris, Caroline M F Durif, Steven Shema, Reidun M Bjelland, Anne Berit Skiftesvik, Howard I Browman
The European eel (Anguilla anguilla) has one of the longest migrations in the animal kingdom. It crosses the Atlantic Ocean twice during its life history, migrating between the spawning area in the Sargasso Sea and Europe, where it is widely distributed. The leptocephalus larvae drift with the Gulf Stream and other currents for more than a year and metamorphose into glass eels when they arrive on the continental shelf and move toward coastal areas. The mechanisms underlying glass eel orientation toward the coast and into freshwater systems are poorly known...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28629886/-evaluation-of-the-effectiveness-of-a-mindfulness-and-self-compassion-program-to-reduce-stress-and-prevent-burnout-in-primary-care-health-professionals
#7
Gloria Aranda Auserón, M Rosario Elcuaz Viscarret, Carmen Fuertes Goñi, Victoria Güeto Rubio, Pablo Pascual Pascual, Enrique Sainz de Murieta García de Galdeano
OBJECTIVE: To evaluate the effectiveness of a Mindfulness and Self-Compassion Program on the levels of stress and burnout in Primary Care health professionals. DESIGN: Randomised, controlled clinical trial. PARTICIPANTS AND SETTING: Training in Mindfulness was offered to 1,281 health professionals in Navarra (Spain) Primary Care, and 48 of them accepted. The participants were randomly assigned to groups: 25 to the intervention group, and the remaining 23 to the control group...
June 16, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28629436/disease-compass-a-navigation-system-for-disease-knowledge-based-on-ontology-and-linked-data-techniques
#8
Kouji Kozaki, Yuki Yamagata, Riichiro Mizoguchi, Takeshi Imai, Kazuhiko Ohe
BACKGROUND: Medical ontologies are expected to contribute to the effective use of medical information resources that store considerable amount of data. In this study, we focused on disease ontology because the complicated mechanisms of diseases are related to concepts across various medical domains. The authors developed a River Flow Model (RFM) of diseases, which captures diseases as the causal chains of abnormal states. It represents causes of diseases, disease progression, and downstream consequences of diseases, which is compliant with the intuition of medical experts...
June 19, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28629360/conceptualisation-of-job-related-wellbeing-stress-and-burnout-among-healthcare-workers-in-rural-ethiopia-a-qualitative-study
#9
Medhin Selamu, Graham Thornicroft, Abebaw Fekadu, Charlotte Hanlon
BACKGROUND: Wellbeing of healthcare workers is important for the effective functioning of health systems. The aim of this study was to explore the conceptualisations of wellbeing, stress and burnout among healthcare workers in primary healthcare settings in rural Ethiopia in order to inform the development of contextually appropriate interventions. METHODS: A qualitative study was conducted in a rural zone of southern Ethiopia. A total of 52 frontline primary healthcare workers participated in in-depth interviews (n = 18) or Focus Group Discussions (FGDs) (4 groups, total n = 34)...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28627907/the-role-of-empathy-in-experiencing-vicarious-anxiety
#10
Jocelyn Shu, Samuel Hassell, Jochen Weber, Kevin N Ochsner, Dean Mobbs
With depictions of others facing threats common in the media, the experience of vicarious anxiety may be prevalent in the general population. However, the phenomenon of vicarious anxiety-the experience of anxiety in response to observing others expressing anxiety-and the interpersonal mechanisms underlying it have not been fully investigated in prior research. In 4 studies, we investigate the role of empathy in experiencing vicarious anxiety, using film clips depicting target victims facing threats. In Studies 1 and 2, trait emotional empathy was associated with greater self-reported anxiety when observing target victims, and with perceiving greater anxiety to be experienced by the targets...
June 19, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28627073/determination-of-radical-radical-distances-in-light-active-proteins-and-their-implication-for-biological-magnetoreception
#11
Daniel Nohr, Bernd Paulus, Ryan Rodriguez, Asako Okafuji, Robert Bittl, Erik Schleicher, Stefan Weber
Light-generated short-lived radial pairs have been suggested to play pivotal roles in cryptochromes and photolyases. Chryptochromes are very probably involved in magnetic compass sensing in migratory birds and the magnetic-field-dependent behavior of insects. We examined photo-generated transient states in the cryptochrome of Drosophila melanogaster and in the structurally related DNA-repair enzyme Escherichia coli DNA photolyase. Using pulsed EPR spectroscopy, the exchange and dipolar contributions to the electron spin-spin interaction were determined in a straightforward and direct way...
June 19, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28622407/challenges-and-lessons-learned-in-implementing-a-community-academic-partnership-for-drug-prevention-in-a-native-hawaiian-community
#12
Susana Helm, Kanoelani Davis, Anonymous Youth Participants Haumana
OBJECTIVE: The broad purpose of this project is to improve health in Native Hawaiian communities through the prevention of substance use. Our community-academic partnership (CAP) team developed an intervention called Puni Ke Ola for this purpose. This paper provides a brief overview of the intervention, then describes challenges and lessons learned in piloting Puni Ke Ola. METHODS: A single module of the Puni Ke Ola intervention was implemented, after which the intervention leaders (N=3) convened for a debriefing meeting...
June 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28620966/the-embodied-nurse-interdisciplinary-knowledge-exchange-between-compassionate-nursing-and-recent-developments-in-embodied-leadership-studies
#13
Kushwanth Koya, Jane Anderson, Petia Sice
AIM: To report a potential knowledge exchange between nursing studies and the results obtained from a study conducted into the attributes of embodied leadership. BACKGROUND: Leadership theories have been applied to evaluate, improve and train nursing practitioners in several previous studies. However, leadership research has entered a new phase where the focus is to produce sustainable leaders through authenticity and compassion, the same two characteristics identified as being of most success in emergent nursing practice...
June 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28618572/functional-window-of-the-avian-compass
#14
Vishvendra Singh Poonia, Kiran Kondabagil, Dipankar Saha, Swaroop Ganguly
The functional window is an experimentally observed property of the avian compass that refers to its selectivity around the geomagnetic-field strength. We show that the simple radical-pair model, using biologically feasible hyperfine parameters, can qualitatively explain the salient features of the avian compass as observed in behavioral experiments: its functional window, as well as disruption of the compass action by radio-frequency fields of specific frequencies. Further, we show that adjustment of the hyperfine parameters can tune the functional window, suggesting a possible mechanism for its observed adaptation to field variation...
May 2017: Physical Review. E
https://www.readbyqxmd.com/read/28618054/ethics-intimacy-and-sexuality-in-aged-care
#15
Catherine Cook, Vanessa Schouten, Mark Henrickson, Sandra Mcdonald
AIM: To analyse the accounts of staff, family and residents in order to advance ethical insights into intimacy and sexuality in residential care. BACKGROUND: Discourses of ageing readily construct people in residential aged care as post-sexual, vulnerable and at risk of sexual exploitation and therefore expressions of intimacy and sexuality may be responded to as deviant and inherently risky. Staff may manage decision-making tacitly, without recourse to policies and education...
June 15, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28617735/evaluating-the-effectiveness-of-using-a-progressive-muscle-relaxation-technique-on-the-self-efficacy-of-breastfeeding-in-mothers-with-preterm-infants
#16
Soheila Karbandi, Seyedeh Maryam Hosseini, Seyedeh Asieh Hosseini, Farshad Sadeghi, Maryam Hesari, Reza Masoudi
BACKGROUND: Breast milk is a God-given gift that conveys a mother's love and compassion and that is made according to the needs and age of the child. Mothers who are interested in the welfare of their newborns tend to breastfeed their children. Training programs have been shown to improve breastfeeding self-efficacy in terms of both duration and amount. PURPOSE: The aim of this study was to evaluate the effect of using the progressive muscle relaxation (PMR) technique on the self-efficacy of breastfeeding in mothers with preterm infants...
June 14, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28617025/confronting-the-new-epidemic-integrated-care-for-opioid-use-disorders
#17
Christine N Runyan, Amber L Hewitt, Stephen A Martin, Daniel Mullin
The inaugural Collaborative Family Health Care (CFHA) regional conference took place March 17, 2017, in St. Louis, Missouri. The conference theme was opioid use disorders and the potential of medication-assisted treatment using team-based care to address this epidemic. The conference ended with an emphasis on the importance of and strategies for self-care among caregivers working with this population and their families. This intensive meeting was crafted as a proof in concept for CFHA; however, the content was timely with regard to its importance in health care as well as compelling in the opportunity for collaborative care to offer an effective approach...
June 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/28614047/estimating-how-extra-calories-from-alcohol-consumption-are-likely-an-overlooked-contributor-to-youth-obesity
#18
Kate Battista, Scott T Leatherdale
INTRODUCTION: Youth obesity rates in Canada continue to rise. In this study, we produced conservative estimates of the potential excess calories from alcohol use across different alcohol consumption patterns common among Canadian youth to assess whether alcohol use should be considered in future obesity prevention strategies. METHODS: Using data from 10 144 Grade 12 students participating in the COMPASS study (2013/14), we estimated the number of calories consumed per year from alcohol consumption...
June 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28614041/effect-of-short-term-research-training-programs-on-medical-students-attitudes-toward-aging
#19
Dilip V Jeste, Julie Avanzino, Colin A Depp, Maja Gawronska, Xin Tu, Daniel D Sewell, Steven F Huege
Strategies to build a larger workforce of physicians dedicated to research on aging are needed. One method to address this shortage of physician scientists in geriatrics is short-term training in aging research for early-stage medical students. The authors examined the effects of two summer research training programs, funded by the National Institutes of Health, on medical students' attitudes toward aging, using the Carolina Opinions on Care of Older Adults (COCOA). The programs combined mentored research, didactics, and some clinical exposure...
June 14, 2017: Gerontology & Geriatrics Education
https://www.readbyqxmd.com/read/28612453/compassionate-attention-and-regulation-of-eating-behaviour-a-pilot-study-of-a-brief-low-intensity-intervention-for-binge-eating
#20
Cristiana Duarte, José Pinto-Gouveia, R James Stubbs
A low-intensity 4-week intervention that included components of compassion, mindfulness, and acceptance was delivered to women diagnosed with binge eating disorder. Participants were randomly assigned to 1 of 2 conditions: intervention (n = 11) or waiting list control (n = 9). Participants in the intervention condition were invited to practise mindfulness, soothing rhythm breathing, and compassionate imagery practices with a focus on awareness and acceptance of emotional states and triggers to binge eating and engagement in helpful actions...
June 13, 2017: Clinical Psychology & Psychotherapy
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