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https://www.readbyqxmd.com/read/28823113/dual-mode-endomicroscopy-for-detection-of-epithelial-dysplasia-in-the-mouth-a-descriptive-pilot-study
#1
Nico Bodenschatz, Catherine F Poh, Sylvia Lam, Pierre Lane, Martial Guillaud, Calum E MacAulay
Dual-mode endomicroscopy is a diagnostic tool for early cancer detection. It combines the high-resolution nuclear tissue contrast of fluorescence endomicroscopy with quantified depth-dependent epithelial backscattering as obtained by diffuse optical microscopy. In an in vivo pilot imaging study of 27 oral lesions from 21 patients, we demonstrate the complementary diagnostic value of both modalities and show correlations between grade of epithelial dysplasia and relative depth-dependent shifts in light backscattering...
August 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28823038/ultrastructural-morphology-and-phylogeny-of-henneguya-gilbert-n-sp-myxozoa-infecting-the-teleostean-cyphocharax-gilbert-characiformes-curimatidae-from-brazil
#2
Graça Casal, Sérgio C São Clemente, Leila Lopes, Sónia Rocha, Nilza Felizardo, Elsa Oliveira, Saleh Al-Quraishy, Carlos Azevedo
This paper describes light and ultrastructural observations and molecular analysis of a fish-infecting myxosporean, Henneguya gilbert n. sp., which was found infecting the gill epithelium of the commercially important freshwater teleost fish Cyphocharax gilbert (Curimatidae) collected in the estuarine region of Guandu River, Rio de Janeiro State, Brazil. The parasite occurs in the gills, forming whitish spherical to ellipsoidal polysporic cysts measuring up to ~ 750 μm, and displaying asynchronous development...
August 19, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28823025/nanomedicine-associated-with-photodynamic-therapy-for-glioblastoma-treatment
#3
REVIEW
Leonardo B de Paula, Fernando L Primo, Antonio C Tedesco
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most recurrent and malignant astrocytic glioma found in adults. Biologically, GBMs are highly aggressive tumors that often show diffuse infiltration of the brain parenchyma, making complete surgical resection difficult. GBM is not curable with surgery alone because tumor cells typically invade the surrounding brain, rendering complete resection unsafe. Consequently, present-day therapy for malignant glioma remains a great challenge. The location of the invasive tumor cells presents several barriers to therapeutic delivery...
August 19, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/28823016/de-novo-synthesis-of-linoleic-acid-in-multiple-collembola-species
#4
Miriama Malcicka, Joachim Ruther, Jacintha Ellers
Many ecological interactions in communities take place between consumers and the organisms they feed on. Continuous surplus of specific nutritional compounds in the diet may lead to evolutionary changes in the metabolic capacity of the consumer, leaving the biosynthesis of such compounds prone to genetic decay and render organisms auxotrophic. A nutrient that is essential to many organisms is the unsaturated fatty acid, linoleic acid (LA; 18:2n-6), which is important in the maintenance of cell membrane fluidity and as a precursor for signaling molecules...
August 19, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28822990/%C3%AE-%C3%AE-mangostins-induces-autophagy-and-shows-synergistic-effectwith-gemcitabine-in-pancreatic-cancer-cell-lines
#5
Myoungjae Kim, Young-Won Chin, Eun Joo Lee
Pancreatic cancer is one of the most lethal and aggressive cancers in the world. However, no effective treatment is currently available for pancreatic cancer. The objective of this study was to determine the anti-pancreatic cancer effect of α-mangostin (αM) and γ-mangostin (γM) extracted from the pericarp of Garcinia mangostana L.. Both αM and γM reduced the viability of pancreatic cancer cells MIA PaCa-2 and PANC-1 in a dose-dependent manner. These compounds induced apoptosis by increasing c-PARP and c-Caspase 3 levels...
August 21, 2017: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/28822927/comparative-ozone-responses-of-cutleaf-coneflowers-rudbeckia-laciniata-var-digitata-var-ampla-from-rocky-mountain-and-great-smoky-mountains-national-parks-usa
#6
Howard S Neufeld, Jennifer Johnson, Robert Kohut
Cutleaf coneflower (Rudbeckia laciniata L. var. digitata) is native to Great Smoky Mountains National Park (GRSM) and an ozone bioindicator species. Variety ampla, whose ozone sensitivity is less well known, is native to Rocky Mountain National Park (ROMO). In the early 2000s, researchers found putative ozone symptoms on var. ampla and rhizomes were sent to Appalachian State University to verify that the symptoms were the result of ozone exposure. In 2011, potted plants were exposed to ambient ozone from May to August...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822911/maullinia-braseltonii-sp-nov-rhizaria-phytomyxea-phagomyxida-a-cyst-forming-parasite-of-the-bull-kelp-durvillaea-spp-stramenopila-phaeophyceae-fucales
#7
Pedro Murúa, Franz Goecke, Renato Westermeier, Pieter van West, Frithjof C Küpper, Sigrid Neuhauser
Phytomyxea are obligate endoparasites of angiosperm plants and Stramenopiles characterised by a complex life cycle. Here Maullinia braseltonii sp. nov., an obligate parasite infecting the bull kelp Durvillaea (Phaeophyceae, Fucales) from the South-Eastern Pacific (Central Chile and Chiloe Island) and South-Western Atlantic (Falkland Islands, UK) is described. M. braseltonii causes distinct hypertrophies (galls) on the host thalli making it easily identifiable in the field. Sequence comparisons based on the partial 18S and the partial 18S-5...
July 13, 2017: Protist
https://www.readbyqxmd.com/read/28822859/a-facile-method-to-prepare-green-nano-phosphors-with-a-large-stokes-shift-and-solid-state-enhanced-photophysical-properties-based-on-surface-modified-gold-nanoclusters
#8
C H Cheng, H Y Huang, M J Talite, W C Chou, J M Yeh, C T Yuan
Colloidal nano-materials, such as quantum dots (QDs) have been applied to light-conversion nano-phosphors due to their unique tunable emission. However, most of the QDs involve toxic elements and are synthesized in a hazardous solvent. In addition, conventional QD nano-phosphors with a small Stokes shift suffered from reabsorption losses and aggregation-induced quenching in the solid state. Here, we demonstrate a facile, matrix-free method to prepare eco-friendly nano-phosphors with a large Stokes shift based on aqueous thiolate-stabilized gold nanoclusters (GSH-AuNCs) with simple surface modifications...
August 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28822848/tetracarboxy-phthalocyanines-from-excited-state-dynamics-to-photodynamic-inactivation-against-bovine-herpesvirus-type-1
#9
Leandro H Z Cocca, Taise M A Oliveira, Fernando Gotardo, Amanda V Teles, Ricardo Menegatti, Jonathas P Siqueira, Cleber R Mendonça, Luiz A M Bataus, Anderson O Ribeiro, Thalita F M Souza, Guilherme R L Souza, Pablo J Gonçalves, Leonardo De Boni
Herein we present the excited state dynamic of zinc and aluminum tetracarboxy-phthalocyanines (ZnPc and AlPc) and its application in the photodynamic inactivation (PDI) of Bovine herpesvirus type 1 (BoHV-1) in vitro. The excited state dynamic provides valuable data to describe the excited state properties of potential optical limiters and/or photosensitizers (PSs), such as: the excited state cross-sections, fluorescence lifetime and triplet state quantum yield. The excited state characterization was performed using three different Z-scan techniques: Single Pulse, White Light Continuum and Pulse Train...
August 12, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28822799/effect-of-application-sequence-of-fluoride-and-cpp-acp-on-remineralization-of-white-spot-lesions-in-primary-teeth-an-in-vitro-study
#10
Ola B Al-Batayneh, Reem A Jbarat, Susan N Al-Khateeb
OBJECTIVE: To explore how application sequence of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride influences remineralization of enamel white spot lesions (WSL) in primary teeth. DESIGN: In this in-vitro study, artificial WSLs were created in 130 primary teeth. Teeth were divided into 4 groups (n=27) and a control group (n=22) and exposed to one of the following remineralization regimens for 10 weeks: Group-1; 500ppm fluoride dentifrice; Group-2; 10% w/v CPP-ACP; Group-3; fluoride applied first, then CPP-ACP; Group-4; CPP-ACP applied first, then fluoride, and Group-5 was control...
August 10, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28822796/papillary-ductal-plugging-is-a-mechanism-for-early-stone-retention-in-brushite-stone-disease
#11
James C Williams, Michael S Borofsky, Sharon B Bledsoe, Andrew P Evan, Fredric L Coe, Elaine M Worcester, James E Lingeman
PURPOSE: Mechanisms of early stone retention within the kidney are understudied and poorly understood. To date, attachment via Randall's plaque is the only widely accepted theory in this regard, best described in idiopathic calcium oxalate stone formers. Brushite stone formers are known to have distinct papillary morphology relative to calcium oxalate stone formers. As such, we sought to determine whether stone attachment mechanisms in such patients may be similarly unique. MATERIALS AND METHODS: Patients undergoing percutaneous and or ureteroscopic procedures for stone removal were consented for endoscopic renal papillary examination and individual stone collection...
August 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28822697/head-and-neck-myiasis-a-case-series-and-review-of-the-literature
#12
José Alcides Almeida de Arruda, Leni Verônica de Oliveira Silva, Pedro Urquiza Jayme Silva, Eugênia Leal de Figueiredo, Gerhilde Callou, Ricardo Alves Mesquita, Belmiro Cavalcanti do Egito Vasconcelos
OBJECTIVE: This study describes 9 cases of myiasis affecting the head and neck region and discusses the demographic distribution, treatment, clinical characteristics, and sequelae of the disease in light of the literature. STUDY DESIGN: The study was performed in 2 steps. In the first part, 9 cases seen over a period of 10 years at the Emergency Department of Hospital da Restauração in Brazil were studied. In the second part, a literature search was performed in PubMed for articles on head and neck myiasis published from 1975 to March 2017...
July 5, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28822451/-the-value-of-serum-free-light-chain-in-differential-diagnosis-of-monoclonal-gammopathy-of-renal-significance
#13
C Li, Y B Wen, H Li, W Su, J Li, J F Cai, L M Chen, X M Li, X W Li
Objective: To investigate the value of serum free light chain (FLC) in differential diagnosis of monoclonal gammopathy of renal significance (MGRS). Methods: Forty-nine hospitalized patients who underwent renal biopsy in Peking Union Medical College Hospital between January 2013 and December 2015 were included. Monoclonal gammopathy was detected by serum protein electrophoresis (SPE), serum immunofixation electrophoresis (IFE), urine IFE and serum FLC. All patients were classified as MGRS (n=32) and monoclonal gammopathy of undetermined significance (MGUS) (n=17)...
August 8, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28822339/effects-of-simulated-n-deposition-on-foliar-nutrient-status-n-metabolism-and-photosynthetic-capacity-of-three-dominant-understory-plant-species-in-a-mature-tropical-forest
#14
Qinggong Mao, Xiankai Lu, Hui Mo, Per Gundersen, Jiangming Mo
Anthropogenic increase of nitrogen (N) deposition has threatened forest ecosystem health at both regional and global scales. In N-limited ecosystems, atmospheric N input is regarded as an important nutrient source for plant growth. However, it remains an open question on how elevated N deposition affects plant growth in N-rich forest ecosystems. To address this question, we used a simulated N deposition experiment in an N-rich mature tropical forest of southern China, with N addition levels as 0kgNha(-1)yr(-1) (Control), 50kgNha(-1)yr(-1) (Low-N), 100kgNha(-1)yr(-1) (Middle-N) and 150kgNha(-1)yr(-1) (High-N), respectively...
August 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822337/photocatalysis-of-estrone-in-water-and-wastewater-comparison-between-au-tio2-nanocomposite-and-tio2-and-degradation-by-products
#15
Kireesan Sornalingam, Andrew McDonagh, John L Zhou, Md Abu Hasan Johir, Mohammad Boshir Ahmed
Gold-modified TiO2 (Au-TiO2) photocatalysts were utilised for the degradation of estrone (E1), a major endocrine disrupting chemical in water and wastewater. Au-TiO2 catalysts were synthesised by a deposition-precipitation method with gold loadings of 0-8% (wt%). The Au-TiO2 nanocomposite exhibited superior activity compared to P25 TiO2 under UVA (λ=365nm), cool white (λ>420nm) and green (λ=523nm) light emitting diodes (LEDs), for treating 1mgl(-1) of E1. The 4wt% Au loading was found to produce the best photocatalytic activity with a rate constant of 2...
August 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822328/the-effects-of-haptic-input-on-biomechanical-and-neurophysiological-parameters-of-walking-a-scoping-review
#16
REVIEW
Alison R Oates, Laura Hauck, Renato Moraes, Kathryn M Sibley
Walking is an important component of daily life requiring sensorimotor integration to be successful. Adding haptic input via light touch or anchors has been shown to improve standing balance; however, the effect of adding haptic input on walking is not clear. This scoping review systematically summarizes the current evidence regarding the addition of haptic input on walking in adults. Following an established protocol, relevant studies were identified using indexed data bases (Medline, EMBASE, PsychINFO, Google Scholar) and hand searches of published review articles on related topics...
August 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28822291/highly-absorbing-multispectral-near-infrared-polymer-nanoparticles-from-one-conjugated-backbone-for-photoacoustic-imaging-and-photothermal-therapy
#17
Haobin Chen, Jian Zhang, Kaiwen Chang, Xiaoju Men, Xiaofeng Fang, Libo Zhou, Dongliang Li, Duyang Gao, Shengyan Yin, Xuanjun Zhang, Zhen Yuan, Changfeng Wu
Semiconducting polymers with specific absorption are useful in various applications, including organic optoelectronics, optical imaging, and nanomedicine. However, the optical absorption of a semiconducting polymer with a determined structure is hardly tunable when compared with that of inorganic semiconductors. In this work, we show that the optical absorption of polymer nanoparticles from one conjugated backbone can be effectively tuned through judicious design of the particle morphology and the persistence length of polymers...
August 12, 2017: Biomaterials
https://www.readbyqxmd.com/read/28822289/assessing-differences-between-ostwald-ripening-and-coalescence-by-rheology-laser-diffraction-and-multiple-light-scattering
#18
J Santos, N Calero, L A Trujillo-Cayado, M C Garcia, J Muñoz
This contribution deals with the study of the influence of surfactant ratio, namely triblock copolymer (Pluronic PE9400) to polyoxyethylene glycerol fatty acid ester (Levenol C201), on the stability of emulsions formulated with a mixture of two biosolvents (N,N Dimethyl Decanamide and D-limonene), which find applications as carriers of agrochemicals. Emulsions containing Pluronic, regardless of the concentration studied, underwent Ostwald ripening while coalescence controlled the destabilization process of emulsions containing Levenol C201 as the only emulsifier...
August 14, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28822288/two-sides-of-the-coin-part-2-colloid-and-surface-science-meets-real-biointerfaces
#19
Barry W Ninham, Kåre Larsson, Pierandrea Lo Nostro
Part 1 revisited developments in lipid and surfactant self assembly over the past 40 years [1]. New concepts emerged. Here we explore how these developments can be used to make sense of and bring order to a range of complex biological phenomena. Together with Part 1, this contribution is a fundamental revision of intuition at the boundaries of Colloid Science and Biological interfaces from a perspective of nearly 50 years. We offer new insights on a unified treatment of self assembly of lipids, surfactants and proteins in the light of developments presented in Part 1...
August 5, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28822287/blue-light-induced-free-radicals-from-riboflavin-in-degradation-of-crystal-violet-by-microbial-viability-evaluation
#20
Ji-Yuan Liang, Jeu-Ming P Yuann, Zong-Jhe Hsie, Shiuh-Tsuen Huang, Chiing-Chang Chen
Crystal violet (CV) is applied in daily use mainly as a commercial dye and antimicrobial agent. Waste water containing CV may affect aquatic ecosystems. Riboflavin, also known as vitamin B2, is non-toxic and an essential vitamin required for the functions of the human body. Riboflavin is photosensitive to UV and visible light in terms of generating reactive oxygen species. This study investigated the potential application of blue light on riboflavin, so as to come up with an effective way of degrading CV during its treatment...
August 12, 2017: Journal of Photochemistry and Photobiology. B, Biology
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