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Wound managment

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https://www.readbyqxmd.com/read/29923636/multiphotonic-staging-of-chronic-wounds-and-evaluation-of-sterile-optical-transparent-bacterial-nanocellulose-covering-a-diagnostic-window-into-human-skin
#1
S Springer, M Zieger, U C Hipler, J Lademann, V Albrecht, R Bueckle, C Meß, M Kaatz, V Huck
BACKGROUND: Diagnostics of healing, infection, and inflammation in chronic wounds in comparison with physiological wound healing in acute wounds may help for therapy decisions toward individualized therapy management. With emerging new optical techniques the coupling of optical diagnostic devices with tissue provides a great challenge. Traditional coupling with cover slips is used since the early days of microscopy. In modern health care, hygienic covering of surfaces is necessary to avoid infections and cross-contaminations...
June 20, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29922571/careful-interpretation-of-the-wound-status-is-needed-with-use-of-antibiotic-impregnated-biodegradable-synthetic-pure-calcium-sulfate-beads-series-of-39-cases
#2
Aditya Menon, Rajeev Soman, Camilla Rodrigues, Sanjay Phadke, Vikas M Agashe
Introduction: The use of antibiotic impregnated biodegradable synthetic high purity calcium sulfate (SHPCS) beads is frequently reported as they offer increased concentration of antibiotics locally, without need for removal. However some wound discharge following their use has been noted. The purpose of this study was to determine any correlation between wound discharge and infection remission. Methodology: Retrospective study of 39 cases of Osteoarticular infections from April 2013 to November 2016 in whom SHPCS beads were used...
2018: Journal of Bone and Joint Infection
https://www.readbyqxmd.com/read/29921799/nutritional-requirements-of-lung-transplant-recipients-challenges-and-considerations
#3
REVIEW
Valerie Jomphe, Larry C Lands, Genevieve Mailhot
An optimal nutritional status is associated with better post-transplant outcomes and survival. Post-lung transplant nutrition management is however particularly challenging as lung recipients represent a very heterogeneous group of patients in terms of age, underlying diseases, weight status and presence of comorbidities. Furthermore, the post-transplant period encompasses several stages characterized by physiological and pathophysiological changes that affect nutritional status of patients and necessitate tailored nutrition management...
June 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29921408/treatment-of-symptomatic-oral-mucositis-with-sodium-hyaluronate-and-synthetic-amino-acid-precursors-of-collagen-in-patients-undergoing-haematopoietic-stem-cell-transplantation
#4
T Ruggiero, R Pol, D Camisassa, S Simiele, L Giaccone, S Carossa
The purpose of the study is to evaluate the clinical effects of Mucosamin® (a spray preparation containing sodium hyaluronate combined with a pool of amino acids of precursor collagen, including L-Proline, L-Leucine, L-Lysine and glycine) on wound healing and pain management of oral mucositis after hematopoietic stem cell transplantation. The importance of professional dental hygiene by dental hygienist in reducing the severity of oral mucositis as unique therapy or in addition to therapy with Mucosamin® was also evaluated...
May 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29921386/autologous-platelet-rich-plasma-for-treatment-of-venous-leg-ulcers-a-prospective-controlled-study
#5
D Etugov, V Mateeva, G Mateev
Venous leg ulcers (VLUs) are chronic difficult-to-treat wounds which affect around 1-2% of the world population. Conventional methods for treatment such as mechanical debridement, occlusive dressings and local antibiotics in case of infection, often lack effectiveness. Autologous platelet-rich plasma (PRP) is an alternative method in the treatment of chronic wounds. PRP contains inflammatory mediators, growth factors, and cytokines that modulate the wound microenvironment to create a better chance for healing...
May 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29920593/radial-artery-fascial-flow-through-free-flap-for-complex-cerebral-revascularization-technical-notes-and-long-term-neurologic-and-radiographic-outcomes
#6
Robert C Rennert, Kristine Ravina, Ben A Strickland, Joshua Bakhsheshian, Joseph Carey, Jonathan J Russin
BACKGROUND: Surgical innovation is critical for the management of challenging cerebrovascular pathology. Flow-through free flaps are versatile composite grafts that combine viable tissue with a revascularization source. Neurosurgical experience with these flaps is limited. OBJECTIVE: To provide an in-depth technical description of the radial artery fascial (and fasciocutaneous) flow-through free flap (RAFF and RAFCF, respectively) for complex cerebral revascularizations...
June 16, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29920252/anti-allodynic-and-anti-hyperalgesic-activities-of-fentanyl-loaded-dermal-clay-fldc-dressings-in-rat-model-of-second-degree-burn-injury
#7
Srinath Rangappa, Krishnaswamy K Rangan, Tirumalai S Sudarshan, S Narasimha Murthy
Second degree burn injury is the most common type of burn injury which usually takes 2-3 weeks for complete healing. However, such patients suffer with intense pain associated with development of hyperalgesia and allodynia. Here, we prepare a silver clay patch using Montmorillonite clay, betaine and silver nitrate. Later, the silver clay patches were loaded with fentanyl. Further, the patches were fabricated into burn wound dressings. The dressings were first subjected to ex vivo skin penetration studies and were later evaluated for thermal hyperalgesia and mechanical allodynia using second degree burn injury rodent model...
June 16, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29917335/assessment-and-management-of-older-people-with-venous-leg-ulcers
#8
Marie Todd
A venous leg ulcer (VLU) is defined as the loss of skin below the knee on the leg or foot in the presence of venous disease, which takes more than two weeks to heal. The prevalence of VLUs is increasing, especially in older people, which will increase the demand for nursing care. Development of a lower leg ulcer should trigger immediate assessment of risk factors for chronic venous disease followed by action to identify the cause and initiate treatment, which should prevent progression to more complex and chronic problems...
June 19, 2018: Nursing Older People
https://www.readbyqxmd.com/read/29916889/a-new-technique-in-management-of-depressed-posttracheostomy-scars
#9
Sevgi Kurt Yazar, Erkan Yüce, Merdan Serin, Memet Yazar, Zeliha Gül, Fatih Irmak, Serhat Selami Şirvan
BACKGROUND: The goals of tracheostomy scar revision are filling of the depressed area, providing easy sliding of skin over the trachea. There are various techniques described to correct this situation. In this article, a modification of split sternocleidomastoid (SCM) muscle flap used in the correction of posttracheostomy defects is described. METHODS: Thirteen patients who had depressed scars after tracheostomy are included in this study. The mean patient age was 44 years (range, 27-56 years)...
June 19, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29915804/using-advanced-wound-care-and-hyperbaric-oxygen-to-manage-wound-complications-following-treatment-of-vulvovaginal-carcinoma
#10
C Griffiths, R S Howell, H Boinpally, E Jimenez, E Chalas, F Musa, S Gorenstein
Postoperative management of patients with vulvar cancer is associated with a high incidence of poor wound healing and radiation -induced late tissue necrosis. This case series demonstrates the impact on wound healing with the use of hyperbaric oxygen therapy and advanced wound care following radical vulvectomy and/or radiation therapy. A retrospective case series was performed of all patients from 2016 to 2017 with lower genital cancer who underwent radical surgery with or without chemoradiation treatment, experienced wound dehiscence or late tissue radionecrosis, and were treated with advanced wound care, including hyperbaric oxygen therapy (HBO)...
May 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29912253/-prevalence-and-susceptibility-pattern-of-bacteria-isolated-from-infected-chronic-wounds-in-adult-patients
#11
Víctor Silva, Alicia Marcoleta, Viviana Silva, Dángelo Flores, Teresa Aparicio, Isabel Aburto, Cecilia Latrach, Naldy Febré
BACKGROUND: Chronic wounds are considered a public health problem that may be complicated by bacterial infections, mainly caused by resistant strains. AIM: To study the bacteria prevalence and antimicrobial susceptibility in samples from adult patients with chronic wounds. METHODS: Patients treated at National Institute of Wounds Foundation between May and July 2014, with chronic ulcers in lower extremities with clinical inflammatory signs were recluted...
April 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29910997/periodontal-treatment-in-cancer-patients-an-interdisciplinary-approach
#12
A M Decker, L S Taichman, N J D'Silva, R S Taichman
Purpose of Review: Dental care is an essential component in the comprehensive treatment for the cancer patient. As such, a review of the literature was completed to determine the relationships between periodontal and dental care in the cancer patient and provide strategic suggestions. Recent Findings: Periodontal treatment must be personalized depending on the patient's current oral health status, systemic status, and progress in treatment. Oral mucositis, periodontal status, and osteonecrosis of the jaw (ONJ) remain periodontal concerns in the cancer patient...
March 2018: Current Oral Health Reports
https://www.readbyqxmd.com/read/29910571/leprosy-associated-chronic-wound-management-using-biomaterials
#13
Srinivasan Sivasubramanian, Sambasivam Mohana, Paulraj Maheswari, Victor Victoria, Ramar Thangam, Jayashri Mahalingam, Gayathri Chandrasekar-Janebjer, Vincent Savariar, Balaraman Madhan, Palani Gunasekaran, Satish S Kitambi
Background: Deformities and neuropathic chronic ulcers are the common features associated with leprosy-cured individuals that impact their quality of life and impair rehabilitation efforts. The challenging aspects for treatment of chronic wounds are the factors that inhibit healing. We reasoned that limited success of various therapeutic interventions could be due to the fact that leprosy-cured individual's physiology gets acclimatized to having a chronic wound that any therapeutic intervention is counterbalanced to maintain status quo at the wound site...
April 2018: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/29909087/critical-appraisal-of-the-quality-of-evidence-addressing-the-diagnosis-prognosis-and-management-of-peripheral-artery-disease-in-patients-with-diabetic-foot-ulceration
#14
Stephen R Ali, Baris A Ozdemir, Robert J Hinchliffe
AIMS: There is a paucity of robust evidence on prevention and management of diabetic foot ulcers (DFUs) to inform treatment. This study appraises the current quality of the evidence addressing diagnosis, prognosis, and management of peripheral artery disease (PAD) in patients with DFUs using a newly devised 21 point scoring (TOPS) disease specific research appraisal tool published by the International Working Group on the Diabetic Foot (IWGDF) and European Wound Management Association...
June 13, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29908932/comparison-of-open-and-closed-hand-fractures-and-the-effect-of-urgent-operative-intervention
#15
Shobhit V Minhas, Louis W Catalano
PURPOSE: To establish and compare the incidence of 30-day postoperative infection in surgically managed open and closed metacarpal and phalangeal fractures, and to determine whether open fractures treated urgently had a lower incidence of postoperative infection. METHODS: We conducted a retrospective analysis of patient demographics, comorbidities, and 30-day infection rates of patients undergoing operative fixation of metacarpal, proximal, or middle phalanx fractures from 2008 to 2015 using the American College of Surgeons' National Surgical Quality Improvement Program database...
June 13, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29908624/vaginoplasty-complications
#16
REVIEW
Cecile A Ferrando
Complications after vaginoplasty surgery for the transgender woman exist. These adverse outcomes can be minor and easily treatable, whereas others are considered major events and require ongoing care. Adverse outcomes can be immediate or remote after surgery and include bleeding, hematoma, infection, delayed wound healing, neovaginal stenosis, visceral injury, and fistula. Patients may also experience pelvic floor disorders after surgery. Providers performing these surgeries and those providers caring for postoperative patients should be aware of the incidence of these complications and the treatment options that exist to manage them...
July 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29907602/improvised-first-aid-techniques-for-terrorist-attacks
#17
EDITORIAL
Andrew Loftus, Harvey Pynn, Paul Parker
Terrorist acts occur every day around the world. Healthcare professionals are often present as bystander survivors in these situations, with none of the equipment or infrastructure they rely on in their day-to-day practice. Within several countries there has been a move to disseminate the actions to take in the event of such attacks: in the UK, Run, Hide, Tell , and in the USA, Fight Back This paper outlines how a very basic medical knowledge combined with everyday high-street items can render highly effective first aid and save lives...
June 15, 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29907210/nonoperative-management-of-penetrating-abdominal-solid-organ-injuries-in-children
#18
Reid Sakamoto, Kazuhide Matsushima, Amory de Roulet, Kristine Beetham, Aaron Strumwasser, Damon Clark, Kenji Inaba, Demetrios Demetriades
BACKGROUND: Nonoperative management (NOM) of penetrating solid organ injuries (SOI) has not been well described in the pediatric population. The objective of this study was to characterize the epidemiology, injury patterns, and factors associated with trial and failure of NOM. METHODS: This is a retrospective cohort analysis of the National Trauma Data Bank for the period of 2007-2014. The study population included patients ≤18 y with penetrating injury to the liver, spleen, or kidney...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29907107/complete-abdominal-wound-and-anastomotic-leak-with-diffuse-peritonitis-closure-achieved-by-an-abdominal-vacuum-sealing-drainage-in-a-critical-ill-patient-a-case-report
#19
Yusuke Fujii, Yoshitsugu Tajima, Shunsuke Kaji, Takashi Kishi, Yoshiko Miyazaki, Takahito Taniura, Noriyuki Hirahara
BACKGROUND: Negative pressure wound therapy (NPWT) is a widely accepted technique to treat local infectious wounds of the skin, subcutaneous tissue, fascia, or muscle. Recently, several reports describing the efficacy of NPWT for various types of fistulas and anastomotic leaks have been published. We herein describe a patient with an open abdominal wound due to colonic anastomotic leakage and diffuse peritonitis, in whom abdominal vacuum sealing (AVS) as a modified NPWT was useful for the management of this complex wound...
June 15, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29906614/assessing-risk-and-related-complications-after-reversal-of-combat-associated-ostomies
#20
Luke R Johnston, Matthew J Bradley, Carlos J Rodriguez, Michael P McNally, Eric A Elster, James E Duncan
BACKGROUND: During the past decade of conflict, numerous casualties sustained injuries requiring the formation of an ostomy. However, outcomes in those casualties undergoing ostomy reversal have yet to be analyzed. We review the experience and identify risk factors for complications after ostomy reversal in a series of combat casualties at our military treatment facility. STUDY DESIGN: A retrospective review of combat casualties managed with a diverting ostomy who underwent ostomy reversal at our military treatment facility over a 13 year period...
June 12, 2018: Journal of the American College of Surgeons
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