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Wound managment

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https://www.readbyqxmd.com/read/29456901/awake-craniotomy-for-the-treatment-of-a-cortical-pseudoaneurysm-in-a-pregnant-patient
#1
Hirad Hedayat, Daniel R Felbaum, John E Reynolds, Rashid M Janjua
Neurosurgical pathologies presenting during pregnancy are uncommon. If present, the situation creates a unique diagnostic, observational, and therapeutic challenge as both lives are placed at potential risk. Surgical procedures during pregnancy are approached carefully as physiological stressors associated with surgery and anesthesia may cause fetal or maternal compromise. We present the only known case of a pseudoaneurysm treated with an awake craniotomy, allowing us to abate the risks associated with general anesthesia in pregnancy...
December 7, 2017: Curēus
https://www.readbyqxmd.com/read/29455840/cardiac-surgery-outcomes-in-patients-with-chronic-lymphocytic-leukemia
#2
Yuanjia Zhu, Andrew J Toth, Ashley M Lowry, Eugene H Blackstone, Brian T Hill, Stephanie L Mick
BACKGROUND: Surgical outcomes of patients with chronic lymphocytic leukemia (CLL) undergoing cardiac surgery are limited. Our objectives were to investigate hospital morbidity and mortality after open cardiac surgery in CLL versus non-CLL patients. METHODS: From May 1995 to May 2015, 157 patients with CLL and 55,917 without and older than 47 years underwent elective cardiac surgery at Cleveland Clinic. By Rai criteria, 79 CLL patients (56%) were low risk (class 0), 13 (9...
February 15, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29453974/genetically-modified-bone-mesenchymal-stem-cells-with-tgf-%C3%AE-3-improve-wound-healing-and-reduce-scar-tissue-formation-in-a-rabbit-model
#3
Mingyong Li, Lin Qiu, Wei Hu, Xiang Deng, Hanfeng Xu, Youhan Cao, Zijian Xiao, Liangyu Peng, Shawn Johnson, Lyundup Alexey, Paul A Kingston, Qing Li, Yuanyuan Zhang
Extensive scar tissue formation often occurs after severe burn injury, trauma, or as one of complications after surgical intervention. Despite significant therapeutic advances, it is still a significant challenge to manage massive scar tissue formation while also promoting normal wound healing. The goal of this study was to investigate the therapeutic effect of bone mesenchymal stem cells (BMSCs) that were genetically modified to overexpress transforming growth factor-beta 3 (TGF-β 3 ), an inhibitor of myofibroblast proliferation and collagen type I deposition, on full-thickness cutaneous wound healing in a rabbit model...
February 14, 2018: Experimental Cell Research
https://www.readbyqxmd.com/read/29452627/case-series-of-18-patients-with-lower-extremity-wounds-treated-with-a-concentrated-surfactant-based-gel-dressing
#4
Catherine R Ratliff
The purpose of this case series was to assess the performance of a concentrated surfactant-based gel (CSG) dressing on 18 patients in the outpatient setting over 4 weeks. Wounds selected were full thickness, had been presented for greater than 4 weeks, and were located on the lower extremities. Patients were given the CSG dressing and instructed on its use. On follow-up clinic visits, the wound was assessed, measurements were obtained, Pressure Ulcer Scale for Healing (PUSH) Tool scores completed, and satisfaction with the dressing was solicited...
March 2018: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/29451938/the-management-of-cerebrospinal-fluid-leak-after-anterior-cervical-decompression-surgery
#5
Jiliang Zhai, Ripul R Panchal, Ye Tian, Shujie Wang, Lijuan Zhao
Cerebrospinal fluid (CSF) leak is a rare but potentially troublesome and occasionally catastrophic complication after anterior cervical decompression surgery. There is limited literature describing this complication, and the management of CSF leak varies. The aim of this study was to retrospectively review the treatment of cases with CSF leak and develop a management algorithm. A series of 14 patients with CSF leak from January 2011 to May 2016 were included in this study. Their characteristics, management of CSF leak, and outcomes were documented...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29451600/american-tegumentary-leishmaniasis-diagnostic-and-treatment-challenges-in-a-clinical-case
#6
Jully Oyama, Fabiana Borges Padilha Ferreira, Carolina Cella Conter, Daniele Stéfanie Sara Lopes Lera-Nonose, Áquila Carolina Fernandes Herculano Ramos-Milaré, Eneide Aparecida Sabaini Venazzi, Thaís Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni
This clinical case presents a patient with a raised and ulcerative lesion with erythematous edges in the mouth, on the lower lip that was unsuccessfully treated as herpes labialis. Clinical data and laboratory tests (Montenegro skin test, indirect immunofluorescence, direct parasite search and polymerase chain reaction) led to the diagnosis of American tegumentary leishmaniasis caused by Leishmania (Viannia) sp. Treatment with pentavalent antimonial (Glucantime®) for 120 days was not effective and administration of amphotericin B for 30 days resulted in wound healing...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29445967/the-use-of-free-nonvascularized-fibular-graft-in-the-induced-membrane-technique-to-manage-post-traumatic-bone-defects
#7
Barakat El-Alfy, Mazen Abulsaad, Wail Lotfy Abdelnaby
PURPOSE: The aim of the present study is to assess the results of free nonvascularized fibular graft in the induced membrane technique to manage bone defects. MATERIALS AND METHODS: Fifteen patients with segmental skeletal defects were treated by the induced membrane technique using free nonvascularized fibular graft. The ages ranged from 20 to 48 years with an average of 32 years. The cause of the defects was post-traumatic bone loss in all cases. The defects were located in the distal femur in nine cases, proximal tibia in two cases and middle third of the tibia in four cases...
February 14, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29444705/health-economic-evaluation-of-moist-wound-care-in-chronic-cutaneous-leishmaniasis-ulcers-in-afghanistan
#8
Hans-Christian Stahl, Faridullah Ahmadi, Sami Mohammad Nahzat, Heng-Jin Dong, Kurt-Wilhelm Stahl, Rainer Sauerborn
BACKGROUND: The present health economic evaluation in Afghanistan aims to support public health decision makers and health care managers to allocate resources efficiently to appropriate treatments for cutaneous leishmaniasis (CL) elicited by Leishmania tropica or Leishmania major. METHODS: A decision tree was used to analyse the cost and the effectiveness of two wound care regimens versus intra-lesional antimony in CL patients in Afghanistan. Costs were collected from a societal perspective...
February 14, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29443439/complexity-of-the-relationships-of-pain-posttraumatic-stress-and-depression-in-combat-injured-populations-an-integrative-review-to-inform-evidence-based-practice
#9
Nicholas A Giordano, Christine Bader, Therese S Richmond, Rosemary C Polomano
BACKGROUND: Understanding the complex interrelationships between combat injuries, physical health, and mental health symptoms is critical to addressing the healthcare needs of wounded military personnel and veterans. The relationship between injury characteristics, pain, posttraumatic stress disorder (PTSD), and depression among combat-injured military personnel is unique to modern conflicts and understudied in the nursing literature. AIM: This integrative review synthesizes clinical presentations and relationships of combat injury, PTSD, depression, and pain in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) United States military service members and veterans...
February 14, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29441656/patterns-of-wounding-in-hamadryas-baboons-papio-hamadryas-in-north-american-zoos
#10
Jodi N Wiley, Austin Leeds, Kamisha D Carpenter, Corinne J Kendall
In North American zoos, hamadryas baboons (Papio hamadryas) have traditionally been housed as single one-male units (single male groups). In recent years, efforts have been made to house hamadryas in groups composed of multiple one-male units (multi-male groups) to more closely mirror their natural social structure, in addition to all-male or bachelor groups to manage surplus males. Given that the majority of social conflict in hamadryas occurs between males during the acquisition and defense of females, it was thought that managing hamadryas in these multi-male groups would result in increased rates of wounding...
February 14, 2018: Zoo Biology
https://www.readbyqxmd.com/read/29440808/intranasal-ketamine-for-the-management-of-incidental-pain-during-wound-dressing-in-cancer-patients-a-pilot-study
#11
Nivedita Page, Vivek Nirabhawane
Introduction: Cancer wounds need regular dressing; else they develop infection, foul odor, and in extreme cases, maggots. Patients resist dressing due to the severe incidental pain during dressing. Intranasal ketamine was tried as an analgesic to reduce this incidental pain. Materials and Methods: Twenty patients with wounds requiring regular dressing were selected; these patients had a basal pain score of 4/10 and incidental pain score of 7/10 during four consecutive dressings...
January 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29439892/a-human-bite-on-the-scrotum-case-report-and-review-of-management-in-the-emergency-department
#12
Dorothy Ng, Thomas Chan, Sohil Pothiawala
BACKGROUND: Human bites involving the genitalia rarely present to the emergency department (ED). They have the potential to cause life-threatening secondary infections as well as serious physical and functional damage. CASE REPORT: We report a case of an adult male who sustained a human bite to the scrotum, resulting in a ragged laceration on the anterior scrotum, with a devascularized flap and necrotic edges overlying the wound. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Human bites to the scrotum are rare and, hence, the experience of emergency physicians treating patients presenting with these injuries may be minimal...
February 10, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29438147/ulcerated-basal-cell-carcinomas-masquerading-as-venous-leg-ulcers
#13
Catherine N Tchanque-Fossuo, Jillian W Millsop, Mary Ann Johnson, Sara E Dahle, R Rivkah Isseroff
BACKGROUND: Nonmelanoma skin cancers rarely arise from venous leg ulcers (VLUs). Although basal cell carcinoma (BCC) is the most common nonmelanoma skin cancer, its association with lower-extremity ulcers is not as frequently reported as other malignancies. OBJECTIVE: To report a case series of biopsy-proven BCC from lower-extremity ulcers of patients who presented at a multispecialty wound clinic. METHODS: Four male patients (mean age, 82...
March 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29438143/identifying-pain-and-effects-on-quality-of-life-from-chronic-wounds-secondary-to-lower-extremity-vascular-disease-an-integrative-review
#14
Stacy Newbern
GENERAL PURPOSE: To provide information to enable better assessment and management of patients with lower extremity vascular disease (LEVD) chronic wound pain. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you will be able to: ABSTRACT: A lack of wound pain validation and provider understanding about the effect of pain on quality of life are the biggest barriers to pain management for patients with chronic wound pain...
March 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29436991/antibacterial-strategies-for-wound-dressing-preventing-infection-and-stimulating-healing
#15
Zhengwen Li, Menno Knetsch
Wound management is an important and increasing global issue. Infection of a wound can cause a delay in wound healing and pain, but also more serious complications like tissue necrosis or even sepsis, which can lead to loss of tissue, limbs or life. Antibacterial agents have been introduced into wound infection care. In this review, we provide an insight into the current antibacterial strategies of wound dressings, including wound infection process, antibacterial agents, and controlled drug release systems...
February 13, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29435826/efficacy-of-bovine-lactoferrin-in-the-post-surgical-treatment-of-patients-suffering-from-bisphosphonate-related-osteonecrosis-of-the-jaws-an-open-label-study
#16
Francesco Calvani, Antimo Cutone, Maria Stefania Lepanto, Luigi Rosa, Valentino Valentini, Piera Valenti
Osteonecrosis of the jaws is an emerging pathological condition characterized by un-exposure or exposure of the necrotic bone, independently from the etiology. This term is usually referred to medication-related osteonecrosis of the jaws due to severe adverse reaction to certain medicines, as bisphosphonates, used for the treatment of cancer and osteoporosis. The management of patients with Bisphosphonate-Related Osteonecrosis of the Jaws (BRONJ) remains challenging because surgical and medical interventions may not eradicate this pathology...
February 12, 2018: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/29433670/genistein-induced-anticancer-effects-on-pancreatic-cancer-cell-lines-involves-mitochondrial-apoptosis-g-0-g-1-cell-cycle-arrest-and-regulation-of-stat3-signalling-pathway
#17
Yi-Liang Bi, Min Min, Wei Shen, Yan Liu
BACKGROUND: Genistein is a natural flavonoid that has been reported to exhibit anticancer effects against different types of cancers which include, but are not limited to, breast and oral squamous cell carcinoma. PURPOSE: The present study was designed to evaluate the anticancer effects of the natural flavonoid genistein against pancreatic cancer cell lines and to explore the underlying mechanism. METHODS: Antiproliferative activity was investigated by MTT assay...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29432357/perspectives-of-oncology-nurses-on-complementary-and-alternative-medicine-in-turkey-a-cross-sectional-survey
#18
Zehra Gok Metin, Nur Izgu, Canan Karadas, Ayse Arikan Donmez
In Turkey, between 22.1% and 84.1% of patients with cancer use complementary and alternative medicine (CAM). However, few CAM-related studies have focused on the perspective of oncology nurses. This study aimed to determine the knowledge, attitudes, and practices of Turkish oncology nurses regarding CAM. A descriptive cross-sectional survey of 127 participants was conducted in Ankara, Turkey. A semistructured questionnaire including characteristics, knowledge, attitudes, and practices of oncology nurses toward CAM was administered to participants...
March 2018: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29432322/acute-compartment-syndrome-an-expert-survey-of-orthopedic-trauma-association-ota-members
#19
Cory Collinge, Basem Attum, Paul Tornetta, William Obremskey, Jaimo Ahn, Gudrun Mirick, Andrew Schmidt, Clay Spitler, Chad Coles, Peter Krause
OBJECTIVES: The goal of this study was to describe current opinions of orthopedic trauma experts regarding acute compartment syndrome (ACS). DESIGN: Web-based survey SETTING:: N/A PARTICIPANTS:: Active Orthopedic Trauma Association (OTA) members METHODS:: A 25 item web-based questionnaire was advertised to active members of the OTA. Using a cross-sectional survey study design, we evaluated the perceived importance of ACS, as well as preferences in diagnosis and treatment...
January 24, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29432043/prehospital-application-of-hemostatic-agents-in-iraq-and-afghanistan
#20
Steven G Schauer, Michael D April, Jason F Naylor, Joseph K Maddry, Allyson A Arana, Michael A Dubick, Andrew D Fisher, Cord W Cunningham, Anthony E Pusateri
INTRODUCTION: Hemorrhage is the leading cause of death on the battlefield. Development of chitosan- and kaolin-based hemostatic agents has improved hemorrhage control options. Sparse data exists on the use of these agents in the prehospital, combat setting. We describe recent use of these agents and compare patients receiving hemostatic to the baseline population. METHODS: We used a series of emergency department (ED) procedure codes to identify patients within the Department of Defense Trauma Registry (DODTR) from January 2007 to August 2016...
February 12, 2018: Prehospital Emergency Care
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