keyword
https://read.qxmd.com/read/38652067/machine-learning-based-perivascular-space-volumetry-in-alzheimer-disease
#1
JOURNAL ARTICLE
Katerina Deike, Andreas Decker, Paul Scheyhing, Julia Harten, Nadine Zimmermann, Daniel Paech, Oliver Peters, Silka D Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Okka Kimmich, Jens Wiltfang, Claudia Bartels, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H Munk, Annika Spottke, Nina Roy, Michael Wagner, Sandra Roeske, Michael T Heneka, Frederic Brosseron, Alfredo Ramirez, Laura Dobisch, Steffen Wolfsgruber, Luca Kleineidam, Renat Yakupov, Melina Stark, Matthias C Schmid, Moritz Berger, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Gabor C Petzold, Anja Schneider, Alexander Effland, Alexander Radbruch
OBJECTIVES: Impaired perivascular clearance has been suggested as a contributing factor to the pathogenesis of Alzheimer disease (AD). However, it remains unresolved when the anatomy of the perivascular space (PVS) is altered during AD progression. Therefore, this study investigates the association between PVS volume and AD progression in cognitively unimpaired (CU) individuals, both with and without subjective cognitive decline (SCD), and in those clinically diagnosed with mild cognitive impairment (MCI) or mild AD...
April 23, 2024: Investigative Radiology
https://read.qxmd.com/read/38647181/motor-band-sign-is-specific-for-amyotrophic-lateral-sclerosis-and-corresponds-to-motor-symptoms
#2
JOURNAL ARTICLE
Charlotte Zejlon, Stefan Sennfält, Johannes Finnsson, Bryan Connolly, Sven Petersson, Tobias Granberg, Caroline Ingre
OBJECTIVE: Magnetic resonance imaging can detect neurodegenerative iron accumulation in the motor cortex, called the motor band sign. This study aims to evaluate its sensitivity/specificity and correlations to symptomatology, biomarkers, and clinical outcome in amyotrophic lateral sclerosis. METHODS: This prospective study consecutively enrolled 114 persons with amyotrophic lateral sclerosis and 79 mimics referred to Karolinska University Hospital, and also 31 healthy controls...
April 22, 2024: Annals of Clinical and Translational Neurology
https://read.qxmd.com/read/38635167/how-theory-of-mind-leads-to-positive-first-impressions
#3
JOURNAL ARTICLE
Chloe C Hudson, Mark A Sabbagh, Kate L Harkness
A common conjecture is that social success relies on "theory of mind"-the everyday skill of imputing mental states to others. We test the hypothesis that individuals with stronger theory of mind skills and motivation garner more positive first impressions because of how they interact with others. Participants included 334 young adults who were paired with a peer for a first-time meeting. Dyads completed a cooperative Lego-building task, which was videotaped and later coded for behavioral manifestations of theory of mind by independent raters...
April 18, 2024: Journal of Experimental Psychology. General
https://read.qxmd.com/read/38624223/validation-of-the-delirium-observation-screening-scale-in-long-term-care-facilities-in-flanders
#4
JOURNAL ARTICLE
Kelly Sabbe, Roos van der Mast, Tinne Dilles, Bart Van Rompaey
AIM: The aim of this study was to validate the Delirium Observation Screening Scale (DOSS) in a population of long-term care facility (LTCF) residents in Flanders. Currently there is no validated screening tool for delirium available for the population in this setting in Flanders. METHODS: A multisite, cross-sectional study was conducted in six LTCFs. A total of 338 residents aged 65 years and older were included. Sociodemographic and clinical data, including data from the Montreal Cognitive Assessment (MoCA), Confusion Assessment Method (CAM) and DOSS, were obtained by three trained nurse researchers...
April 16, 2024: Geriatrics & Gerontology International
https://read.qxmd.com/read/38614955/inter-rater-agreement-between-patient-and-proxy-reported-cognitive-functioning-in-intensive-care-unit-patients-a-cohort-study
#5
JOURNAL ARTICLE
Malin Brandvold, Tone Rustøen, Milada Hagen, Jan Stubberud, Mark van den Boogaard, Kristin Hofsø
BACKGROUND: Health status, including cognitive functioning before critical illness, is associated with long-term outcomes in intensive care unit survivors. Premorbid data are therefore of importance in longitudinal studies. Few patients can self-report at intensive care admission. Consequently, proxy assessments of patients' health status are used. However, it remains unclear how accurately proxies can report on an intensive care patient's cognitive status. OBJECTIVES: The aim of this study was to examine the agreement between patient- and proxy-reporting of the Cognitive Failures Questionnaire and to compare the agreement between proxy reports using the latter questionnaire and the Informant Questionnaire of Cognitive Decline in the Elderly as a reference...
April 12, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://read.qxmd.com/read/38614044/influence-of-anosognosia-on-patient-reported-outcomes-for-psychiatric-symptoms-and-quality-of-life-in-huntington-s-disease
#6
JOURNAL ARTICLE
David A Isaacs, Kaitlyn R Hay, Jennifer Hoadley, Katherine E McDonell, Amy E Brown, Amy Wynn, Daniel O Claassen, Jessie Gibson
INTRODUCTION: Anosognosia, defined as reduced awareness of one's deficit or symptom, is common in Huntington's disease (HD) and detectable at each disease stage. The impact of anosognosia on self-reporting in HD populations is critical to understand given growing use of patient-reported outcomes in HD clinical care and research. We aimed to determine the influence of anosognosia on patient-reported outcome measures assessing psychiatric symptoms and quality of life in HD. METHODS: We enrolled HD patients to complete a battery of patient-reported and rater-administered measures, including the Anosognosia Scale, at baseline and 6 months later...
April 9, 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38597895/the-socialvidstim-a-video-database-of-positive-and-negative-social-evaluation-stimuli-for-use-in-social-cognitive-neuroscience-paradigms
#7
JOURNAL ARTICLE
Laura M Tully, Mary Blendermann, Jeffrey R Fine, Lauren N Zakskorn, Matilda Fritz, Gabriella E Hamlett, Shannon T Lamb, Anna K Moody, Julenne Ng, Narimes Parakul, Bryn M Ritter, Raisa Rahim, Grace Yu, Sandra L Taylor
This paper describes the SocialVidStim - a database of video stimuli available to the scientific community depicting positive and negative social evaluative and neutral statements. The SocialVidStim comprises 53 diverse individuals reflecting the demographic makeup of the United States, ranging from 9-41 years old, saying 20-60 positive and 20-60 negative social evaluative statements (e.g., "You are a very trustworthy/annoying person"), and 20-60 neutral statements (e.g., "The sky is blue"), totaling 5,793 videos post-production...
April 10, 2024: Social Cognitive and Affective Neuroscience
https://read.qxmd.com/read/38591829/safety-intervention-for-improving-functioning-in-suicidal-attempters-strong-a-secondary-prevention-study-study-rationale-and-research-protocol
#8
JOURNAL ARTICLE
Natalia Roberto, Mireia Vazquez, Joaquim Radua, Jose Carlos Pariente, Emma Muñoz-Moreno, Carlos Laredo, Lorenzo Bracco, Tábatha Fernández, Sara Martín-Parra, Anabel Martínez-Aran, Jose Sánchez-Moreno, Pilar Saiz, Miguel Ruiz-Veguilla, Roger Borras, Alba Toll, Matilde Elices, Paolo Brambilla, Philippe Courtet, Víctor Perez-Solà, Eduard Vieta, Iria Grande
BACKGROUND: Suicide is one of the most largely preventable causes of death worldwide. The aim of the STRONG study is to assess the effectiveness of a specific intervention (an extended Safety Planning Intervention) called iFightDepression-SURVIVE (iFD-S) in suicidal attempters by changes in psychosocial functioning. As secondary outcomes, quality of life, cognitive performance, clinical state and neuroimaging correlates will be considered. OBJECTIVE: To describe the rationale and design of the STRONG study, an extension of the SURVIVE study, a national multicenter cohort about on prevention in suicidal attempters...
August 25, 2023: Span J Psychiatry Ment Health
https://read.qxmd.com/read/38588968/establishing-the-reliability-of-the-step-test-evaluation-of-performance-on-stairs-steps-in-multiple-sclerosis
#9
JOURNAL ARTICLE
Patrick G Monaghan, Ana M Daugherty, Nora E Fritz
OBJECTIVE: To establish the inter- and intra-rater reliability of The Step Test Evaluation of Performance on Stairs (STEPS) for people with Multiple Sclerosis (PwMS) and examine its relation to clinical mobility measures, cognition, and activity levels. DESIGN AND SETTING: STEPS performance was rated by three raters at the initial visit. Two raters observed the STEPS performance via videotape at the initial visit and then one week later. Participants also completed in lab clinical mobility tests and cognitive assessments at their initial visit...
April 6, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38582026/hippocampal-subfields-and-thalamic-nuclei-associations-with-clinical-outcomes-in-multiple-sclerosis-an-ultrahigh-field-mri-study
#10
JOURNAL ARTICLE
Tales Santini, Chenyi Chen, Wen Zhu, Jr-Jiun Liou, Elizabeth Walker, Shruthi Venkatesh, Nadim Farhat, Andrea Sajewski, Salem Alkhateeb, Manojkumar Saranathan, Zongqi Xia, Tamer S Ibrahim
BACKGROUND: Previous studies have shown that thalamic and hippocampal neurodegeneration is associated with clinical decline in Multiple Sclerosis (MS). However, contributions of the specific thalamic nuclei and hippocampal subfields require further examination. OBJECTIVE: Using 7 Tesla (7T) magnetic resonance imaging (MRI), we investigated the cross-sectional associations between functionally grouped thalamic nuclei and hippocampal subfields volumes and T1 relaxation times (T1-RT) and subsequent clinical outcomes in MS...
February 27, 2024: Multiple Sclerosis and related Disorders
https://read.qxmd.com/read/38570060/reliability-of-proxy-reports-on-patient-reported-outcomes-measures-in-stroke-an-updated-systematic-review
#11
JOURNAL ARTICLE
Claire Reimer, Sherlissa Ali-Thompson, Raseel Althawadi, Niall O'Brien, Catherine Nora Moran, Anne Hickey
OBJECTIVES: With the rising global burden of stroke-related morbidity, and increased focus on patient-centered healthcare, patient reported outcome measures (PROMs) are increasingly used to inform healthcare decision-making. Some stroke patients with cognitive or motor impairments are unable to respond to PROMs, so proxies may respond on their behalf; the reliability of which remains unclear. The aim of the study is to update a 2010 systematic review to investigate the inter-rater reliability of proxy respondents answering PROMs for stroke patients...
April 1, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38566948/reliability-of-clinical-judgment-for-evaluation-of-informed-consent-in-mental-health-settings-and-the-validation-of-the-evaluation-of-informed-consent-to-treatment-eict-scale
#12
JOURNAL ARTICLE
Nicola Di Fazio, Donato Morena, Federica Piras, Fabrizio Piras, Nerisa Banaj, Giuseppe Delogu, Felice Damato, Paola Frati, Vittorio Fineschi, Stefano Ferracuti, Gabriele Sani, Claudia Dacquino
INTRODUCTION: The competence assessment to give informed consent in the legal and healthcare settings is often performed merely through clinical judgment. Given the acknowledged limited reliability of clinician-based evaluation in the mental health sector, particularly for the assessment of competence to consent, our objective was to ascertain the dependability of clinical judgment when evaluating the ability of schizophrenia patients to make choices about their health. METHODS: The potential convergence between clinical evaluation and scores from a new standardized assessment (the "Evaluation of Informed Consent to Treatment" - "EICT" scale) was therefore tested...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38566288/when-stroke-survivors-self-ratings-are-inconsistent-with-the-ratings-of-others-a-cohort-study-examining-biopsychosocial-factors-associated-with-impaired-self-awareness-of-functional-abilities
#13
JOURNAL ARTICLE
Kate V Cameron, Jennie L Ponsford, Dean P McKenzie, Renerus J Stolwyk
Background Stroke survivors' self-ratings of functional abilities are often inconsistent with ratings assigned by others (e.g. clinicians), a phenomenon referred to as 'impaired self-awareness' (ISA). There is limited knowledge of the biopsychosocial contributors and consequences of post-stroke ISA measured across the rehabilitation journey. This multi-site cohort study explored biopsychosocial correlates of ISA during subacute rehabilitation (inpatient) and at 4 months post-discharge (community-dwelling)...
February 2024: Brain Impairment: a Multidisciplinary Journal of the Australian Society for the Study of Brain Impairment
https://read.qxmd.com/read/38566178/cross-cultural-adaptation-and-psychometric-validation-of-point-of-care-outcome-assessment-tools-in-chinese-palliative-care-clinical-practice
#14
JOURNAL ARTICLE
Yunyun Dai, Claire E Johnson, Jinfeng Ding, Yongyi Chen, Alanna Connolly, Lianjun Wang, Barbara A Daveson
BACKGROUND: A standardized national approach to routinely assessing palliative care patients helps improve patient outcomes. However, a quality improvement program-based on person centered outcomes within palliative care is lacking in Mainland China. The well-established Australian Palliative Care Outcome Collaboration (PCOC) national model improves palliative care quality. This study aimed to culturally adapt and validate three measures that form part of the PCOC program for palliative care clinical practice in China: The PCOC Symptom Assessment Scale (PCOC SAS), Palliative Care Problem Severity Scale (PCPSS), Palliative Care Phase...
April 3, 2024: BMC Palliative Care
https://read.qxmd.com/read/38557214/response-latencies-during-confrontation-picture-naming-in-aphasia-are-proxy-measurements-sufficient
#15
JOURNAL ARTICLE
Barnali Mazumdar, Nora De la Mora, Teresa Roberts, Alexander Swiderski, Maria Kapantzoglou, Gerasimos Fergadiotis
PURPOSE: Anomia, or word-finding difficulty, is a prevalent and persistent feature of aphasia, a neurogenic language disorder affecting millions of people in the United States. Anomia assessments are essential for measuring performance and monitoring outcomes in clinical settings. This study aims to evaluate the reliability of response time (RT) annotation based on spectrograms and assess the predictive utility of proxy RTs collected during computerized naming tests. METHOD: Archival data from 10 people with aphasia were used...
April 1, 2024: Journal of Speech, Language, and Hearing Research: JSLHR
https://read.qxmd.com/read/38549098/validation-of-a-viable-delirium-detection-test-performed-by-nurses-and-physicians-during-routine-patient-care
#16
JOURNAL ARTICLE
Rashad Soboh, Sharon Gino-Moor, Nizar Jiris, Shira Ginsberg, Ron Oliven
BACKGROUND: Delirium is a frequent mental impairment in geriatric patients hospitalized in acute care facilities. It carries a high risk of complications and is often the first symptom of acute illness. It is clearly important to identify the development of delirium at an early stage, and several short and effective diagnostic tests have been developed and validated for this purpose. Despite this, patients on hospital wards are seldom monitored for signs of emergent delirium, suggesting that compliance with guidelines would be improved by introducing a simpler and more user-friendly test...
March 28, 2024: BMC Geriatrics
https://read.qxmd.com/read/38528366/capuchin-monkeys-sapajus-cebus-apella-categorization-of-photos-of-unknown-male-conspecifics-suggests-attention-to-fwhr-and-a-dominance-bias
#17
JOURNAL ARTICLE
Ashley M Meacham, Meghan J Sosnowski, Heather M Kleider-Offutt, Sarah F Brosnan
The ability to quickly perceive others' rank minimizes costs by helping individuals behave appropriately when interacting with strangers. Indeed, humans and at least some other species can quickly determine strangers' rank or dominance based only on physical features without observing others' interactions or behavior. Nonhuman primates can determine strangers' ranks by observing their interactions, and some evidence suggests that at least some cues to dominance, such as facial width-to-height ratio (fWHR), are also present in other primates...
March 25, 2024: American Journal of Primatology
https://read.qxmd.com/read/38501898/assessing-the-accuracy-of-generative-conversational-artificial-intelligence-in-debunking-sleep-health-myths-mixed-methods-comparative-study-with-expert-analysis
#18
JOURNAL ARTICLE
Nicola Luigi Bragazzi, Sergio Garbarino
BACKGROUND: Adequate sleep is essential for maintaining both individual and public health, positively affecting cognition and well-being, and reducing chronic disease risks. It also plays a significant role in driving the economy, public safety, and managing healthcare costs. Digital tools, including websites, sleep trackers, and apps, are key in promoting sleep health education. Conversational Artificial Intelligence (AI) like ChatGPT offers accessible, personalized advice on sleep health but raises concerns about potential misinformation...
March 14, 2024: JMIR Formative Research
https://read.qxmd.com/read/38483862/street-wise-dog-testing-feasibility-and-reliability-of-a-behavioural-test-battery-for-free-ranging-dogs-in-their-natural-habitat
#19
JOURNAL ARTICLE
Svenja Capitain, Giulia Cimarelli, Urša Blenkuš, Friederike Range, Sarah Marshall-Pescini
Behavioural scientists are increasingly recognizing the need to conduct experiments in the wild to achieve a comprehensive understanding of their species' behaviour. For domestic dogs (Canis familiaris), such progress has been slow. While the life in human households is often regarded as dogs' natural habitat, this classification disregards most of the global dog population. The value of experimentally testing free-ranging dogs' cognition and behaviour is increasingly being recognized, but no comprehensive test batteries have been conducted on those populations so far, leaving the feasibility and reliability of such endeavours unknown...
2024: PloS One
https://read.qxmd.com/read/38472235/classification-and-automatic-scoring-of-arousal-intensity-during-sleep-stages-using-machine-learning
#20
JOURNAL ARTICLE
Hyewon Han, Min Jae Seong, Janghun Hyeon, Eunyeon Joo, Junhyoung Oh
Arousal during sleep can result in sleep fragmentation and various physiological effects, impairing cognitive function and raising blood pressure and heart rate. However, the current definition of arousal has limitations in assessing both amplitude and duration, making it challenging to measure sleep fragmentation accurately. Moreover, there is inconsistency among inter-raters in arousal scoring, which renders it susceptible to subjective variability. Therefore, this study aims to identify a highly accurate classifier for each sleep stage by employing optimized feature selection and machine learning models...
March 12, 2024: Scientific Reports
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