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https://www.readbyqxmd.com/read/27915250/importance-of-fumarate-and-nitrate-reduction-regulatory-protein-for-proliferation-for-intestinal-proliferation-of-vibrio-vulnificus
#1
Takehiro Kado, Takashige Kashimoto, Kohei Yamazaki, Shunji Ueno
The sepsis caused by Vibrio vulnificus is characterized by an average incubation period of 26 hours and a high mortality rate exceeding 50%. The fast growth and dissemination of V. vulnificus in vivo lead to poor clinical outcomes in patients. Therefore, elucidation of the proliferation mechanisms of this organism in vivo may lead to development of an effective therapeutic strategy. In this study, we focused on the low oxygen concentration in the intestinal milieu because of its drastic difference from that in the air...
December 2, 2016: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/27915196/identification-and-characterization-of-a-new-dapoxetine-impurity-by-nmr-transformation-of-n-oxide-by-cope-elimination
#2
András Darcsi, Ákos Rácz, Szabolcs Béni
Unknown impurity associated with the degradation process of dapoxetine base was isolated. The structure elucidation of this new compound using accurate mass data, IR and NMR spectroscopy is presented herein. The unambiguous resonance assignment concluded to the formation of geometrical isomers of cinnamyloxynaphtalenes via Cope elimination of dapoxetin-N-oxide, the major oxidative and metabolic degradation product of dapoxetine. An efficient and simple synthetic approach has also been developed for the synthesis of dapoxetine-N-oxide for the first time and cinnamyloxynaphtalene in order to confirm the proposed degradation pathway and structures of the degradation products...
November 27, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27915098/organic-liquid-mobility-induced-by-smoldering-remediation
#3
L Kinsman, J L Torero, J I Gerhard
Laboratory column experiments plus analytical and numerical modeling together suggest that, under certain conditions, downward organic liquid mobilization can occur and impact smoldering behavior. This applies for organic liquids mixed with inert sand subjected to smoldering as thermal treatment. The observed effects include increased peak temperatures (here by up to 35%) and increased treatment times (here by up to 30%). Downward organic liquid migration occurs when (i) injected Darcy air flux is less than a threshold value (here less than 3cm/s), (ii) treatment systems are tall (here 90cm, not 30cm), and (iii) the organic liquid is temperature-sensitive (viscosity less than 0...
November 18, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27915048/protective-effects-of-green-tea-and-its-main-constituents-against-natural-and-chemical-toxins-a-comprehensive-review
#4
REVIEW
Maryam Rameshrad, Bibi Marjan Razavi, Hossein Hosseinzadeh
Toxins are natural or chemical poisonous substances with severe side effects on health. Humans are generally exposed by widespread toxic contaminations via air, soil, water, food, fruits and vegetables. Determining a critical antidote agent with extensive effects on different toxins is an ultimate goal for all toxicologists. Traditional medicine is currently perceived as a safe and natural approach against toxins. In this regard, we focused on the protective effects of green tea (Camellia sinensis) and its main components such as catechin, epicatechin, epicatechin gallate, gallocatechin, epigallocatechin and epigallocatechin gallate as a principal source of antioxidants against both natural and chemical toxins...
November 30, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27914859/fine-and-ultrafine-atmospheric-particulate-matter-at-a-multi-influenced-urban-site-physicochemical-characterization-mutagenicity-and-cytotoxicity
#5
Yann Landkocz, Frédéric Ledoux, Véronique André, Fabrice Cazier, Paul Genevray, Dorothée Dewaele, Perrine J Martin, Capucine Lepers, Anthony Verdin, Lucie Courcot, Saâd Boushina, François Sichel, Maurizio Gualtieri, Pirouz Shirali, Dominique Courcot, Sylvain Billet
Particulate Matter (PM) air pollution is one of the major concerns for environment and health. Understanding the heterogeneity and complexity of fine and ultrafine PM is a fundamental issue notably for the assessment of PM toxicological effects. The aim of this study was to evaluate mutagenicity and cytotoxicity of a multi-influenced urban site PM, with or without the ultrafine fraction. For this purpose, PM2.5-0.3 (PM with aerodynamic diameter ranging from 0.3 to 2.5 μm) and PM2.5 were collected in Dunkerque, a French coastal industrial city and were extensively characterized for their physico-chemical properties, including inorganic and organic species...
November 30, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27914830/dermatophagoides-pteronyssinus-changes-in-sensitisation-in-the-past-11-years-and-comparison-with-other-centres-in-mexico
#6
E M Navarrete-Rodríguez, J R Fernández-Soto, B E Del Rio-Navarro, O J Saucedo-Ramírez, J J L Sienra-Monge
BACKGROUND: House dust mites are a ubiquitous air allergen in the human habitat. It has been shown that exposure to them is a fundamental factor in sensitisation and development of atopic disease. The objective of the study was to analyse changes in sensitisation to Dermatophagoides pteronyssinus (Der p.) in children treated in a tertiary level care hospital in Mexico City for a period of 11 years and compare with other studies carried out in Mexico. METHODS: A retrospective study was performed at the Hospital Infantil de México Federico Gómez (HIMFG)...
November 30, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27914781/incident-air-kerma-to-absorbed-organ-dose-conversion-factors-for-breast-and-lung-in-pa-thorax-radiography-the-effect-of-patient-thickness-and-radiation-quality
#7
A Kelaranta, P Toroi, P Vock
PURPOSE: Converting the measurable quantities to patient organ doses in projection radiography is usually based on a standard-sized patient model and a specific radiation quality, which are likely to differ from the real situation. Large inaccuracies can therefore be obtained in organ doses, because organ doses are dependent on the exposure parameters, exposure geometry and patient anatomy. In this study, the effect of radiation quality and patient thickness on the organ dose conversion factors were determined...
November 30, 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27914775/assessment-of-background-gamma-radiation-levels-using-airborne-gamma-ray-spectrometer-data-over-uranium-deposits-cuddapah-basin-india-a-comparative-study-of-dose-rates-estimated-by-agrs-and-pgrs
#8
D Srinivas, V Ramesh Babu, I Patra, Shailesh Tripathi, M S Ramayya, A K Chaturvedi
The Atomic Minerals Directorate for Exploration and Research (AMD) has conducted high-resolution airborne gamma ray spectrometer (AGRS), magnetometer and time domain electromagnetic (TDEM) surveys for uranium exploration, along the northern margins of Cuddapah Basin. The survey area includes well known uranium deposits such as Lambapur-Peddagattu, Chitrial and Koppunuru. The AGRS data collected for uranium exploration is utilised for estimating the average absorbed rates in air due to radio-elemental (potassium in %, uranium and thorium in ppm) distribution over these known deposit areas...
November 30, 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27914645/comparison-of-diverse-estimation-methods-for-personal-exposure-to-air-pollutants-and-associations-with-allergic-symptoms-the-allergy-gene-environment-link-angel-study
#9
Young-Min Kim, Jihyun Kim, Youngshin Han, Byung-Jae Lee, Dong-Chull Choi, Hae-Kwan Cheong, Byoung-Hak Jeon, Inbo Oh, Gwi-Nam Bae, Jae Young Lee, Chang-Heok Kim, SungChul Seo, Su Ryeon Noh, Kangmo Ahn
We estimated the exposure to ambient air pollutants and analyzed the associations with allergic diseases. We enrolled 177 children with atopic dermatitis (AD) and 70 asthmatic adults living in Seoul Metropolitan Area, Korea, and followed for 17months between August 2013 and December 2014. Parents or patients recorded symptom scores on a daily basis. Exposure to particulate matter with a diameter <10μm (PM10) and nitrogen dioxide (NO2) was estimated in four different ways in each individual, using the AQ1 (measurements from the nearest air quality monitoring station to residential houses), AQ2 (measurements modified from AQ1 with the indoor level of air pollutants and time activity of each individual), AQ1-DI, and AQ2-DI (measurements modified from AQ1 and AQ2, respectively, with daily inhalation intakes of air pollutants)...
November 30, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27914642/chemical-and-physical-properties-of-biomass-burning-aerosols-and-their-ccn-activity-a-case-study-in-beijing-china
#10
Zhijun Wu, Jing Zheng, Yu Wang, Dongjie Shang, Zhoufei Du, Yuanhang Zhang, Min Hu
Biomass burning emits large amounts of both trace gases and particles into the atmosphere. It plays a profound role in regional air quality and climate change. In the present study, an intensive campaign was carried out at an urban site in Beijing, China, in June 2014, which covered the winter wheat harvest season over the North China Plain (NCP). Meanwhile, two evident biomass-burning events were observed. A clear burst in ultrafine particles (below 100nm in diameter, PM1) and subsequent particle growth took place during the events...
November 30, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27914443/converting-sunlight-into-audible-sound-by-means-of-the-photoacoustic-effect-the-heliophone
#11
N B Roozen, C Glorieux, L Liu, M Rychtáriková, T Van der Donck, A Jacobs
One hundred and thirty-five years after Alexander Graham Bell and his assistant Charles Sumner Tainter explored the photoacoustic effect, and about 40 years after Rosencwaig and Gersho modeled the effect in a photoacoustic cell configuration, the phenomenon is revisited in a "Heliophone" device that converts sunlight into sound. The light is focused on a carbon blackened copper coated Kapton foil in an acoustic cell by means of a compound parabolic collimator, and its intensity is modulated by a mechanical chopper...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27914440/computational-study-of-the-piccolo-evidence-for-chaotic-tones
#12
N Giordano
Direct numerical solutions of the Navier-Stokes equations have been used to compute tones produced by a model of the piccolo. The behavior depends on the angle at which the air jet is directed at the embouchure hole and the displacement of the jet center from the embouchure edge. Values of the jet angle and displacement are found that produce pure tones with spectra similar to those of real piccolo tones. The behavior of calculated tones as a function of the blowing speed u is studied, and it is found that unsteady behavior can occur depending on the value of u, the jet angle, and the jet displacement...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27914397/predicting-the-sabine-absorption-coefficients-of-fibrous-absorbers-for-various-air-backing-conditions-with-a-frequency-dependent-diffuseness-correction
#13
Cheol-Ho Jeong
Fibrous absorbers can be installed with various air backing conditions to fulfil a given low frequency acoustic requirement. Since absorber manufacturers cannot provide the absorption coefficients for all possible mounting conditions, acousticians have difficulties knowing the absorption characteristics of their own configurations. This study aims to predict the absorption coefficient for various mounting conditions from a single measurement of an arbitrary mounting condition by extracting the air flow resistivity of the test specimen and the frequency-dependent effect of the chamber on the measured absorption coefficients...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27914351/photocatalytic-degradation-of-industrial-pulp-and-paper-mill-effluent-using-synthesized-magnetic-fe2o3-tio2-treatment-efficiency-and-characterizations-of-reused-photocatalyst
#14
Wennie Subramonian, Ta Yeong Wu, Siang-Piao Chai
In this work, heterogeneous photocatalysis was used to treat pulp and paper mill effluent (PPME). Magnetically retrievable Fe2O3-TiO2 was fabricated by employing a solvent-free mechanochemical process under ambient conditions. Findings elucidated the successful incorporation of Fe2O3 into the TiO2 lattice. Fe2O3-TiO2 was found to be an irregular and slightly agglomerated surface morphology. In comparison to commercial P25, Fe2O3-TiO2 exhibited higher ferromagnetism and better catalyst properties with improvements in surface area (58...
November 30, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27914309/unique-approach-to-sensorimotor-training-with-a-new-device-combining-air-cushion-with-stochastic-translations-a-prospective-randomized-controlled-clinical-trial
#15
Christian Mittermaier, Maximilian Schindler, Benjamin Loader, Thomas Waldhoer, Clemens Ambrozy, Richard Crevenna, Karin Pieber
Sensorimotor training with a wide variety of available devices represents an important component in rehabilitation and prevention of different sports injuries and chronic diseases. The purpose of this study was to evaluate the effects of a sensorimotor training with a newly developed device, which consists of an instable platform moving on an air cushion, providing dynamic balance training by tilting and unanticipated stochastic translations on postural control. Seventy-two healthy young subjects were included in this prospective, randomized, controlled, and observer-blinded study...
November 25, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27914271/individual-exposure-estimates-may-be-erroneous-when-spatiotemporal-variability-of-air-pollution-and-human-mobility-are-ignored
#16
Yoo Min Park, Mei-Po Kwan
This study aims to empirically demonstrate the necessity to consider both the spatiotemporal variability of air pollution and individual daily movement patterns in exposure and health risk assessment. It compares four different types of exposure estimates generated by using (1) individual movement data and hourly air pollution concentrations; (2) individual movement data and daily average air pollution data; (3) residential location and hourly pollution levels; and (4) residential location and daily average pollution data...
November 30, 2016: Health & Place
https://www.readbyqxmd.com/read/27914144/outdoor-air-pollution-and-pterygium-in-korea
#17
Ki Woong Lee, Yoon Hyeong Choi, Sung Ha Hwang, Hae Jung Paik, Mee Kum Kim, Won Ryang Wee, Dong Hyun Kim
We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008-2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], ozone [O₃], nitrogen dioxide [NO₂], and sulfur dioxide levels [SO₂]) for 2 years preceding the ocular examinations were acquired...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27914026/limbal-stem-cell-and-oral-mucosal-epithelial-transplantation-from-ex-vivo-cultivation-in-lscd-induced-rabbits-histology-and-immunologic-study-of-the-transplant-epithelial-sheet
#18
Napaporn Tananuvat, Kanokkan Bumroongkit, Chainarong Tocharusa, Umnat Mevatee, Aphisek Kongkaew, Somsanguan Ausayakhun
PURPOSE: To evaluate the results of cultivated limbal epithelial and oral mucosal epithelial transplantation (CLET and COMET) in limbal stem cell deficiency (LSCD)-induced rabbit model. MATERIALS AND METHODS: Six New Zealand white rabbits were divided into two groups of three rabbits each. Limbal tissue was harvested from the first group, and oral mucosal biopsy was obtained from the second group. The tissues were cultured using an explant technique with amniotic membrane as a substrate and co-culture with the 3T3 fibroblast and air-lifting method...
December 2, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27913958/the-effect-of-mass-transfer-parameterization-and-ice-retention-on-the-scavenging-and-redistribution-of-so2-by-a-deep-convective-cloud
#19
Vladan Vučković, Dragana Vujović
A chemistry module with the aqueous chemistry coupled with the complex 3D nonhydrostatic atmospheric model is used to investigate how the representation of gas-aqueous mass transfer and ice retention affect the SO2 redistribution in the presence of a convective cloud. Gas uptake to the liquid water is calculated using both Henry's law equilibrium (HE) and kinetic mass transport (KMT). The constant retention coefficients for SO2 (k ret = 0.46) and for H2O2 (k ret = 0.64) are used. It is shown that the amount of SO2 in the air at higher altitudes (10-12 km) is greater when partial retention (PR) is included...
December 2, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27913918/new-technique-to-prevent-prolonged-air-leak-use-of-tachosuture-technique
#20
Tatsuya Nishida, Iwao Mikami, Yoshitaka Fujii
Prolonged air leak (defined as air leak >7 days), caused by pulmonary resection or alveolar-pleural fistula, increases postoperative morbidity, prolongs hospital stay and increases healthcare costs. We describe a new technique ('Tachosuture' technique) to prevent prolonged air leak. The key point of this new technique is that air leak is classified into three types and an absorbable suture is added to a TachoSil(®) patch in each type to prevent detachment from the lung parenchyma. Between August 2013 and March 2016, 40 patients underwent thoracoscopic surgery using 'Tachosuture' technique...
December 2, 2016: General Thoracic and Cardiovascular Surgery
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