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Splenic infarction

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https://www.readbyqxmd.com/read/27921152/proximal-occlusion-of-medium-sized-vessels-with-the-penumbra-occlusion-device-a-study-of-safety-and-efficacy
#1
E Jambon, F Petitpierre, V Brizzi, V Dubuisson, Y Le Bras, N Grenier, F Cornelis
PURPOSE: To retrospectively investigate the safety and efficacy of hybrid proximal coiling of various medium-sized vessels (4 to 8 mm) using the Penumbra Occlusion Device (POD). MATERIALS AND METHODS: From October 2014 to February 2016, 37 proximal embolizations were performed with PODs in 36 patients (mean age: 50.8, range: 10-86; 29 male, 7 female). Vessel occlusions were achieved under fluoroscopic guidance using a 2.7 French microcatheter. Among the 36 vessels targeted, 16 were splenic arteries, 11 renal arteries, 4 mesenteric arteries, 3 arteriovenous fistulae, 1 iliac artery, and 1 gonadal vein...
December 5, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27920483/outcomes-of-partial-splenic-embolization-in-patients-with-massive-splenomegaly-due-to-idiopathic-portal-hypertension
#2
Omer Ozturk, Gonca Eldem, Bora Peynircioglu, Taylan Kav, Aysegul Görmez, Barbaros Erhan Cil, Ferhun Balkancı, Cenk Sokmensuer, Yusuf Bayraktar
AIM: To determine the outcomes of partial splenic embolization (PSE) for massive splenomegaly due to idiopathic portal hypertension (IPH). METHODS: In this prospective study, we evaluated the characteristics and prognosis of consecutive patients with IPH who underwent PSE for all indications at a single medical center between June 2009 and January 2015. The inclusion criteria were: presence of hypersplenism, massive splenomegaly, and resultant pancytopenia. The exclusion criteria were: presence of other diseases causing portal hypertension...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27919929/interleukin-37-and-dendritic-cells-treated-with-interleukin-37-plus-troponin-i-ameliorate-cardiac-remodeling-after-myocardial-infarction
#3
Ruirui Zhu, Haitao Sun, Kunwu Yu, Yucheng Zhong, Huairui Shi, Yuzhen Wei, Xin Su, Wenbin Xu, Quan Luo, Fangyuan Zhang, Zhengfeng Zhu, Kai Meng, Xiaoqi Zhao, Yuzhou Liu, Yi Mao, Peng Cheng, Xiaobo Mao, Qiutang Zeng
BACKGROUND: Excessive immune-mediated inflammatory reactions play a deleterious role in postinfarction ventricular remodeling. Interleukin-37 (IL-37) emerges as an inhibitor of both innate and adaptive immunity. However, the exact role of IL-37 and IL-37 plus troponin I (TnI)-treated dendritic cells (DCs) in ventricular remodeling after myocardial infarction (MI) remains elusive. METHODS AND RESULTS: MI was induced by permanent ligation of the left anterior descending artery...
December 5, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27802212/contrast-enhanced-ultrasound-to-evaluate-organ-microvascularization-after-operative-versus-endovascular-treatment-of-visceral-artery-aneurysms
#4
Karin Pfister, Piotr M Kasprzak, Ernst M Jung, René Müller-Wille, Walter Wohlgemuth, Reinhard Kopp, Wilma Schierling
PURPOSE: To evaluate the organ microvascularization after operative versus endovascular treatment of visceral artery aneurysms (VAAs) by contrast-enhanced ultrasound (CEUS) and colour-coded duplex sonography (CCDS). METHOD AND MATERIALS: Between April 1995 to January 2016, 168 patients (78 males, 90 females; median age: 62 years) were diagnosed with VAAs at our hospital site. 60/168 patients (36%) fulfilled treatment criteria and had either open (29/60, 48%) or endovascular (31/60, 52%) aneurysm repair...
October 12, 2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27777380/aging-dysregulates-d-and-e-series-resolvins-to-modulate-cardiosplenic-and-cardiorenal-network-following-myocardial-infarction
#5
Ganesh V Halade, Vasundhara Kain, Laurence M Black, Sumanth D Prabhu, Kevin A Ingle
Post-myocardial infarction (MI), overactive inflammation is the hallmark of aging, however, the mechanism is unclear. We hypothesized that excess influx of omega 6 fatty acids may impair resolution, thus impacting the cardiosplenic and cardiorenal network post-MI. Young and aging mice were fed on standard lab chow (LC) and excess fatty acid (safflower oil; SO)-enriched diet for 2 months and were then subjected to MI surgery. Despite similar infarct areas and left ventricle (LV) dysfunction post-MI, splenic mass spectrometry data revealed higher levels of arachidonic acid (AA) derived pro-inflammatory metabolites in young-SO, but minimal formation of docosanoids, D- and E- series resolvins in SO-fed aged mice...
October 18, 2016: Aging
https://www.readbyqxmd.com/read/27773790/partial-mhc-class-ii-constructs-as-novel-immunomodulatory-therapy-for-stroke
#6
Gil Benedek, Arthur A Vandenbark, Nabil J Alkayed, Halina Offner
The worldwide prevalence of stroke continues to rise despite recent successes in treating acute ischemic stroke. With limited patient eligibility and associated risk of tPA and mechanical thrombectomy, new preventive and therapeutic modalities are needed to stave the rising wave of stroke. Inflammation plays a key role in brain damage after cerebral ischemia, and novel therapies that target pro-inflammatory cells have demonstrated promise for treatment for stroke. Partial MHC class II constructs have been shown to prevent and/or reverse clinical signs of various inflammatory diseases such as experimental autoimmune encephalomyelitis, collagen-induced arthritis and experimental autoimmune uveitis, by reducing the number and frequency of activated cells in the damaged CNS...
October 31, 2016: Neurochemistry International
https://www.readbyqxmd.com/read/27757174/direct-needle-puncture-and-embolization-of-splenic-artery-pseudoaneurysm-in-case-of-chronic-atrophic-calcific-pancreatitis
#7
Amit Shrivastava, Jagadeesh Singh Rampal, D Nageshwar Reddy, Guduru Venkat Rao
BACKGROUND: Gastro-Intestinal bleeding remains a frequent clinical dilemma and common cause of hospitalization, morbidity and mortality. CASE REPORT: We report a case of pseudo aneurysm of splenic artery developed after an episode of acute on chronic pancreatitis which was treated by direct percutaneous puncture of pseudoaneurysm and embolization by coils. CONCLUSIONS: The aim was to preserve the main splenic artery and avoid the complications of splenic artery embolization like infarcts and abscess...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27752606/spontaneous-dissection-of-celiac-trunk-with-concurrent-splenic-artery-dissection
#8
Seo In Lee, Jin Joo Kim, Hyuk Jun Yang, Keun Lee
Isolated spontaneous dissection of the celiac trunk is rarely diagnosed in acute abdominal pain. We present two cases of celiac trunk and splenic artery dissection with splenic infarction. Patients were successfully managed and stabilized by medical treatment. Isolated celiac trunk dissection can be fatal, therefore providers should be careful not to overlook this entity.
December 2015: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/27733945/segmental-arterial-mediolysis-mimics-systemic-vasculitis
#9
Melike Kalfa, Hayriye Kocanaoğulları, Gonca Karabulut, Hakan Emmungil, Celal Çınar, Zevcet Yılmaz, Sercan Gücenmez, Yasemin Kabasakal
Segmental arterial mediolysis (SAM) is a rare, nonarteriosclerotic, noninflammatory vascular disease and mostly affects medium-to-large sized abdominal arteries as well as presents with hemorrhages in the abdominal cavity. We report the case of a patient with SAM of the celiac, right renal, jejunal branch of the superior mesenteric, left gastric, and splenic arteries who was diagnosed by excluding other causes and in whom transcatheter embolization was performed in two different sessions, but he died because of an undefined reason...
September 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27661203/laparoscopic-treatment-of-presinusoidal-schistosomal-portal-hypertension-associated-with-postoperative-endoscopic-treatment-results-of-a-new-approach
#10
Renata P Colaneri, Fabrício F Coelho, Roberto de Cleva, Paulo Herman
AIM: To propose a laparoscopic treatment for schistosomal portal hypertension. METHODS: Ten patients with schistosomiasis and portal hypertension, with previous gastrointestinal hemorrhage from esophageal varices rupture, were evaluated. Patients were subjected to a laparoscopic procedure, with ligature of splenic artery and left gastric vein. Upper gastrointestinal endoscopy was performed on the 30th postoperative day, when esophageal varices diameter was measured and band ligature performed...
September 22, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27645145/the-spleen-contributes-importantly-to-myocardial-infarct-exacerbation-during-post-ischemic-reperfusion-in-mice-via-signaling-between-cardiac-hmgb1-and-splenic-rage
#11
Yikui Tian, Dongfeng Pan, Mahendra D Chordia, Brent A French, Irving L Kron, Zequan Yang
The spleen plays a critical role in post-infarct myocardial remodeling. However, the role of the spleen in exacerbating myocardial infarction (MI) during acute ischemia/reperfusion (I/R) injury is unknown. The present study tests the hypothesis that splenic leukocytes are activated by substances released from ischemic myocardium to subsequently exacerbate myocardial injury during reperfusion. The left coronary artery in C57BL/6 mice underwent various durations of occlusion followed by 60 min of reperfusion (denoted as min/min of I/R) with or without splenectomy prior to I/R injury...
November 2016: Basic Research in Cardiology
https://www.readbyqxmd.com/read/27617630/group-b-streptococcal-tricuspid-valve-endocarditis-with-splenic-infarction-after-an-elective-abortion
#12
P Zhu, Y Sun, S Zheng
Tricuspid valve endocarditis is mainly found in intravenous drug abusers, and with splenic infarction in obstetric and gynaecologic practice is rare. We report the case of a 37-year-old woman with tricuspid infective endocarditis and splenic infarction after an elective abortion. The infected tricuspid valve and infarcted spleen were removed at one-stage operation. Systemic circulation arterial embolism should be considered when treating patients with right-sided endocarditis and a history of obstetrical procedures...
February 18, 2016: West Indian Medical Journal
https://www.readbyqxmd.com/read/27611010/partial-splenic-embolization-to-permit-continuation-of-systemic-chemotherapy
#13
Jose Hugo M Luz, Paula M Luz, Edson Marchiori, Leonardo A Rodrigues, Hugo R Gouveia, Henrique S Martin, Igor M Faria, Roberto R Souza, Roberto de Almeida Gil, Alexandre de M Palladino, Karina B Pimenta, Henrique S de Souza
Systemic chemotherapy treatments, commonly those that comprise oxaliplatin, have been linked to the appearance of distinctive liver lesions that evolves to portal hypertension, spleen enlargement, platelets sequestration, and thrombocytopenia. This outcome can interrupt treatment or force dosage reduction, decreasing efficiency of cancer therapy. We conducted a prospective phase II study for the evaluation of partial splenic embolization in patients with thrombocytopenia that impeded systemic chemotherapy continuation...
September 9, 2016: Cancer Medicine
https://www.readbyqxmd.com/read/27609328/safety-and-effectiveness-of-total-splenic-vessel-ligations-in-paediatric-patients-with-splenomegaly
#14
Chen Zhen, Ma Lishuang, Zhang Jinshan, Qiao Guoliang, Zhang Zhen, Liu Shuili, Zhang Jun, Guan Kaoping, Li Long
BACKGROUNDS: Splenomegaly may contribute to hypersplenism and can result in thrombocytopenia. Many approaches are used to treat splenomegaly; however, the current management of splenomegaly has intrinsic limitations or disadvantages. Now, we initiate a new approach, that of total splenic vessel (artery and vein) ligations (TSVLs) in paediatric patients with splenomegaly. The purpose of our study is to evaluate the results obtained with TVSLs procedure for paediatric patients. PATIENTS AND METHODS: Seventeen paediatric patients with splenomegaly were screened for enrolment into this retrospective analysis...
October 2016: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/27603351/hereditary-pancreatitis-of-3-chinese-children-case-report-and-literature-review
#15
Li-Na Dai, Ying-Wei Chen, Wei-Hui Yan, Li-Na Lu, Yi-Jing Tao, Wei Cai
BACKGROUND: Hereditary pancreatitis (HP) is quite rare and is distinguished by incomplete penetrance presentation as early-onset relapsing pancreatitis, usually beginning in childhood. HP is now known to be commonly relevant to mutations in the PRSS1 (gene-encoding cationic trypsinogen), SPINK1 (serine protease inhibitor, Kazal type 1), CFTR (cystic fibrosis), carboxypeptidase A1 (CPA1), and chymotrypsin C (CTRC) genes as reported in some Caucasian studies. HP has a variable spectrum of severity and may develop complications...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27599418/mantle-cell-lymphoma-presenting-with-spontaneous-splenic-rupture
#16
Yukako Maeda-Sakagami, Yasuhiro Tanaka, Yusuke Koba, Isaku Shinzato, Takayuki Ishikawa
A 48-year-old man was transferred to our emergency room because of sudden-onset epigastric pain and nausea. Abdominal contrast-enhanced computed tomography (CT) showed splenomegaly with splenic infarction and intra-abdominal bleeding, suggestive of splenic rupture. An emergent open splenectomy was performed. His spleen was markedly swollen and showed continuous bleeding due to a laceration. On histopathological examination, his spleen was filled with abnormal tumor cells. He was diagnosed as having mantle cell lymphoma based on the findings of immunohistochemical and cytogenetic analyses of the spleen...
August 2016: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/27592617/biomimicking-platelet-monocyte-interactions-as-a-novel-targeting-strategy-for-heart-healing
#17
Bill Cheng, Elsie K W Toh, Kun-Hung Chen, Yuan-Chih Chang, Che-Ming J Hu, Han-Chung Wu, Lee-Young Chau, Peilin Chen, Patrick C H Hsieh
In patients who survive myocardial infarction, many go on to develop congestive heart failure (CHF). Despite ongoing efforts to develop new approaches for postinfarction therapy, there are still no effective therapeutic options available to CHF patients. Currently, the delivery of cardioprotective drugs relies entirely on passive uptake via the enhanced permeability and retention (EPR) effect which occurs in proximity to the infarction site. However, in ischemic disease, unlike in cancer, the EPR effect only exists for a short duration postinfarction and thus insufficient for meaningful cardioprotection...
September 5, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27545464/-application-of-da-vinci-surgical-robot-in-the-dissection-of-splenic-hilar-lymph-nodes-for-gastric-cancer-patients-with-total-gastrectomy
#18
Kun Yang, Xinzu Chen, Weihan Zhang, Xiaolong Chen, Jiankun Hu
OBJECTIVE: To investigate the feasibility and safety of Da Vinci surgical robot in the dissection of splenic hilar lymph nodes for gastric cancer patients with total gastrectomy. METHODS: Clinical data of two cases who underwent total gastrectomy for cardia cancer at our department in January 2016 were analyzed retrospectively. RESULTS: Two male patients were 62 and 55 years old respectively, with preoperative diagnosis as cT2-3N0M0 and cT1-2N0M0 gastric cancer by gastroscope and biopsy, and both received robotic total gastrectomy spleen-preserving splenic hilar lymph node dissection successfully...
August 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27510310/surgical-treatment-for-thoracoabdominal-intra-aortic-thrombus-with-multiple-infarctions-a-case-report
#19
Kenichiro Uchida, Mitsuharu Hosono, Toshihiko Shibata, Daisuke Kaku, Tomonori Yamamoto, Takafumi Terada, Naoki Shinyama, Yasumitsu Mizobata
BACKGROUND: Mobile intra-aortic thrombus without atherosclerosis, aneurysm, or congenital coagulopathy is very rare, and there are few reports especially in young or middle-aged patients. Furthermore, there are presently no established guidelines or common strategies for the treatment of mobile intra-aortic thrombus. In this case report, we describe the first case of intra-aortic thrombus caused by secondary erythrocytosis and describe the recommended treatment strategy for intra-aortic thrombus...
2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27499832/splenic-artery-aneurysm-presenting-as-a-submucosal-gastric-lesion-a-case-report
#20
Jenny Tannoury, Khalil Honein, Bassam Abboud
We are reporting the rare case of splenic artery aneurysm of 4 cm of diameter presenting as a sub mucosal lesion on gastro-duodenal endoscopy. This aneurysm was treated by endovascular coil embolization and stent graft implantation. The procedure was uneventful. On day 1, the patient presented an acute severe epigastric pain and cardiovascular arrest. Abdominal computed tomography scan showed an active leak of the intravenous contrast dye in the peritoneum from the splenic aneurysm. We performed an emergent resection of the aneurysm, and peritoneal lavage...
July 25, 2016: World Journal of Gastrointestinal Endoscopy
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