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Splenic infarction

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https://www.readbyqxmd.com/read/29351102/fatal-sickling-triggered-by-massive-foreign-particle-embolism-a-case-report-of-unrecognized-indwelling-venous-catheter-drug-abuse-in-sickle-cell-disease
#1
Christopher A Febres-Aldana, Lydia Hernandez Howard
Sickle cell disease (SCD) manifests itself with vaso-occlusive episodes leading to infarction. Placement of intravascular catheters provides a useful route for management of pain crises as well as other complications. However, catheter misuse is a commonly unrecognized problem, which can have lethal consequences. We present a case of fatal splenic sequestration/hyperhemolysis secondary to foreign body pulmonary and systemic embolization due to intravenous administration of hydromorphone pills in a young woman with SCD...
January 18, 2018: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29331296/a-case-of-autosplenectomy-in-sickle-cell-trait-following-an-exposure-to-high-altitude
#2
Uday Yanamandra, Reena Das, Pankaj Malhotra, Subhash Varma
A 24-year-old man presented with acute abdominal pain upon ascent to moderate altitude (3500 m). An immediate evaluation revealed a splenic infarct, and he was evacuated to sea level. Upon recovery, he was sent back to 3500 m without detailed etiological evaluation, whereupon he experienced recurrent episodes of left-side subcostal pain. Imaging suggested autosplenectomy, and workup revealed a negative thrombophilia profile but was positive for sickle cell trait (SCT). Individuals with SCT can be asymptomatic until exposure to severe hypoxia, upon which they can manifest clinically as sickle cell syndrome...
January 10, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29321842/splenic-pedicle-control-during-laparoscopic-de-capsulation-of-a-giant-splenic-cyst
#3
Osama Elhardello, Basil J Ammori
Splenic cysts are a rare entity in the Western population and are either true cysts (primary, 25%) or pseudocysts (secondary, 75%) complicating trauma, haemorrhage or infarction. Congenital or simple splenic cysts are the commonest primary cysts and surgery is recommended for cysts larger than 5 cm as these are prone to infection, bleeding or rupture and for symptomatic or complicated cysts. Splenic preservation techniques using the laparoscopic approach are the most prevalent. We present a case of a giant painful simple splenic cyst treated with laparoscopic de-capsulation with application of a new technique for achieving vascular control, whereby control of the splenic pedicle was achieved using a Nylon tape...
January 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29310334/clinical-efficacy-of-spleen-preserving-distal-pancreatectomy-with-or-without-splenic-vessel-preservation-a-meta-analysis
#4
Ningning Sun, Guangjun Lu, Likun Zhang, Xiaoling Wang, Chunmin Gao, Jieliang Bi, Xiaoyi Wang
OBJECTIVE: The meta-analysis was performed to investigate the clinical efficacy of spleen-preserving distal pancreatectomy with splenic vessel preservation (SPDP-SVP) and spleen-preserving distal pancreatectomy with splenic vessel resection (SPDP-SVR). METHODS: Potential articles were searched on the databases of Pubmed, Embase, and Chinese National Knowledge Infrastructure (CNKI) from January 1988 until March 2017. Weight mean difference (WMD) with 95% confidence interval (CI) was applied to compare the efficacy of SPDP-SVP and SPDP-SVR...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29308370/splenic-infarction-in-two-members-of-the-family-with-sickle-cell-trait-a-case-report-of-rare-complication
#5
Mithilesh Kumar Sinha, Babita Raghuwanshi, Nerbadyswari Deep Bag, Apurba Barman
Sickle cell trait is a highly prevalent condition. It is not a disease. However, it has been associated with few rare complications. Splenic infarction is one among them. The altitude-related hypoxia is the most common predisposing factor for this. The simultaneous occurrence of this complication in more than one member of a family is so rare that possibly, it is the only second such case report. We encountered this in two members of a family, the father and his son. They were on a religious visit to a 12,756 feet high mountain cave, when they developed pain left upper abdomen...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29284415/streptococcus-agalactiae-infective-endocarditis-complicated-by-multiple-mycotic-hepatic-aneurysms-and-massive-splenic-infarction-a-case-report
#6
Pietro Achilli, Angelo Guttadauro, Paolo Bonfanti, Sabina Terragni, Luca Fumagalli, Ugo Cioffi, Francesco Gabrielli, Matilde De Simone, Marco Chiarelli
BACKGROUND: The burden of disease caused by Streptococcus agalactiae has increased significantly among older adults in the last decades. Group B streptococcus infection can be associated with invasive disease and severe clinical syndromes, such as meningitis and endocarditis. CASE PRESENTATION: We present the case of a 56-year-old man who developed multiple mycotic aneurysms of the right hepatic artery and massive splenic infarction as rare complications of Streptococcus agalactiae infective endocarditis...
December 29, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29224017/the-il-2-anti-il-2-complex-attenuates-cardiac-ischaemia-reperfusion-injury-through-expansion-of-regulatory-t-cells
#7
Junhui Xiao, Kunwu Yu, Ming Li, Chuanyin Xiong, Yuzhen Wei, Qiutang Zeng
BACKGROUND/AIMS: Regulatory T cells (Tregs) can suppress immunologic damage in myocardial ischaemia/reperfusion injury (MIRI), however, the isolation and ex vivo expansion of these cells for clinical application remains challenging. Here, we investigated whether the IL-2/anti-IL-2 complex (IL-2C), a mediator of Treg expansion, can attenuate MIRI in mice. METHODS: Myocardial I/R was surgically induced in male C57BL/6 mice, aged 8-10 weeks, that were randomly assigned to 1) sham group (Sham), 2) Phosphate Buffered Saline (PBS), 3) IL-2-anti-IL-2 Ab complex (IL-2C), or 4) sham group, 5) PBS, 6) IL-2C after MIRI, or 7) IL-2C, 8) IL-2C+anti-CD25 mAbs, or 9) IL-2C; 10) IL-2C+anti-TGF-β1 mAbs, 11) IL-2C+anti-IL-10 mAbs...
December 7, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29221152/distal-embolization-versus-combined-embolization-techniques-for-blunt-splenic-injuries-comparison-of-the-efficacy-and-complications
#8
Yon-Cheong Wong, Cheng-Hsien Wu, Li-Jen Wang, Huan-Wu Chen, Kuo-Ching Yuan, Being-Chuan Lin, Yu-Pao Hsu, Shih-Ching Kang
Comparable failure rates of distal or proximal transcatheter arterial embolization (TAE) techniques for blunt splenic injuries have been reported. This study is to investigate the efficacy and complication of combining both TAE techniques. We included 26 patients of blunt splenic injuries for TAE therapy and randomized them into distal TAE and combined TAE groups. A prospective study was performed to compare their demographics, clinical parameters, hemograms, post-TAE splenic infarct volumes, splenic abscess and pancreatitis between the two groups...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29208262/splenic-infarction-and-rupture-due-to-melioidosis
#9
Deng-Wei Chou, Yie-Wen Lin
No abstract text is available yet for this article.
December 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29188161/an-invasive-case-of-left-sided-endocarditis-caused-by-pseudomonas-aeruginosa-in-a-patient-with-history-of-intravenous-drug-abuse
#10
Ankit Mahajan, Mohammad Amer, Ahmad Awan, Fasil Tiruneh, Charu Gandotra, Bryan Curry
Infective endocarditis, caused by Pseudomonas aeruginosa, is rarely seen in clinical practice. It has been reported mainly in intravenous drug abusers (IVDA). We present a case of a 63-year-old male who presented with abdominal pain and fever. Computed tomography (CT) abdomen showed splenic and renal infarct. The blood culture grew Pseudomonas aeruginosa. A transthoracic echocardiogram showed aortic insufficiency with 13 mm mobile vegetation. The patient was started on ceftazidime and tobramycin and, later on, surgery was done for aortic valve replacement...
September 27, 2017: Curēus
https://www.readbyqxmd.com/read/29159070/primary-cytomegalovirus-infection-in-immunocompetent-adults-in-the-united-states-a-case-series
#11
Nathanial Nolan, Umme-Aiman Halai, Hariharan Regunath, LPatrick Smith, Christian Rojas-Moreno, William Salzer
Primary Cytomegalovirus (CMV) infection is often not suspected as a cause of fever of unknown origin (FUO) in immune-competent adults. We present a case-series of symptomatic primary CMV infection in immunocompetent adults presenting as fever of unknown origin (FUO). All patients with CMV serology tested between November 2008 and June 2016 underwent chart review. Cases were defined as those between 18 and 65 years of age with documented fever and elevated serum anti-CMV IgM. Exclusion criteria were organ specific CMV disease, positive serum anti-EBV IgM, or presence of any immunocompromising condition...
2017: IDCases
https://www.readbyqxmd.com/read/29158925/splenic-infarct-and-pulmonary-embolism-as-a-rare-manifestation-of-cytomegalovirus-infection
#12
Prashanth Rawla, Anantha R Vellipuram, Sathyajit S Bandaru, Jeffrey Pradeep Raj
Cytomegalovirus (CMV) is a type of herpes infection that has a characteristic feature of maintaining lifelong latency within the host cell. CMV manifestations can cover a broad spectrum from fever to as severe as pancytopenia, hepatitis, retinitis, meningoencephalitis, Guillain-Barre syndrome, pneumonia, and thrombosis. Multiple case reports of thrombosis associated with CMV have been reported. Deep vein thrombosis or pulmonary embolism is more common in immunocompetent patients while splenic infarct is more common in immunocompromised patients...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/29131251/ischemic-stroke-and-st-elevation-myocardial-infarction-revealing-infective-endocarditis
#13
G-R Joliat, N Halkic, O Pantet, N Ben-Hamouda
In this clinical scenario, we report the case of a patient who presented multiple embolic complications due to mitral infective endocarditis (IE). A 68-year-old woman had extended right hepatectomy for hilar cholangiocarcinoma. Unfortunately, she had multiple postoperative complications and had to be transferred to the Intensive Care Unit. During this stay, we have diagnosed an Enterococcus faecium IE after the occurrence of multiple embolic complications (myocardial infarction, ischemic stroke, digital emboli, splenic emboli, and renal emboli)...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29124843/splenic-vessel-preservation-versus-splenic-vessel-resection-in-laparoscopic-spleen-preserving-distal-pancreatectomy
#14
Baohua Hou, Dailan Xiong, Sheng Chen, Tingting Ma, Chuanzhao Zhang, Yu Zhou, Zi Yin
BACKGROUND: Laparoscopic spleen-preserving distal pancreatectomy for low-grade malignant pancreas tumours was recently demonstrated and can be performed with splenic vessel preservation (SVP) or splenic vessel resection (SVR). Whether one approach is superior to another is still a matter of debate. METHODS: A systematic literature search (PubMed, Embase, Science Citation Index, Springer-Link and Cochrane Central Register of Controlled Trials) was performed. Pooled intra- and post-operative outcomes were evaluated...
November 9, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29078991/splenic-infarction-due-a-common-infection
#15
Javier García-Vázquez, Raquel Plácido Paias, Manuel Portillo Márquez
No abstract text is available yet for this article.
October 24, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29065703/safety-and-effectiveness-of-transarterial-embolization-for-splenic-artery-hemorrhage-in-patients-undergoing-radical-gastrectomy
#16
Kichang Han, Man-Deuk Kim, Michael Diffley, Joon Ho Kwon, Gyoung Min Kim, Woosun Choi, Yong Seek Kim, Junhyung Lee, Jong Yun Won, Do Yun Lee
Background Perigastric lymph nodes are dissected during gastrectomy, potentially resulting in life-threatening postoperative bleeding. Purpose To evaluate the safety and effectiveness of transarterial embolization (TAE) for bleeding from the splenic artery in patients who underwent gastrectomy. Material and Methods Between January 2004 and December 2016, 14,523 patients underwent gastrectomy at our institution, and ten patients (nine men; mean age = 64.7 years; age range = 51-80 years) underwent TAE for postoperative bleeding from the splenic artery...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29059593/splenectomy-protects-aged-mice-from-injury-after-experimental-stroke
#17
Anjali Chauhan, Abdullah Al Mamun, Gabriel Spiegel, Nia Harris, Liang Zhu, Louise D McCullough
Elderly stroke patients and aged animals subjected to experimental stroke have significantly worse functional recovery and higher mortality compared to younger subjects. Activation of the peripheral immune system is known to influence stroke outcome. Prior studies have shown that splenectomy reduces ischemic brain injury in young mice. As immune function changes with aging, it is unclear whether splenectomy will confer similar benefits in aged animals. We investigated the contribution of spleen to brain injury after cerebral ischemia in aged male mice...
September 28, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29046754/splenic-infarct-in-a-patient-with-infectious-mononucleosis-a-rare-presentation
#18
Mustafa Noor, Maryam Sadough, Stephanie Chan, Gurkeerat Singh
We report a case of a 25-year-old obese, currently smoking, female diagnosed with EBV infectious mononucleosis. The patient complained of sudden onset abdominal pain with progressively increasing intensity in the left upper quadrant. Abdominal CT scan showed a wedge infarct of the spleen. We present this rare case that EBV may cause splenic infarct in young adults.
October 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29044906/long-term-follow-up-of-a-massive-conservatively-treated-splenic-infarction-in-a-young-adolescent
#19
Gabriella D'Angelo, Lucia Marseglia, Tiziana Russo, Eloisa Gitto, Pietro Impellizzeri
No abstract text is available yet for this article.
October 18, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29016391/perioperative-and-long-term-outcome-of-the-warshaw-technique-in-laparoscopic-spleen-preserving-distal-pancreatectomy
#20
Kazuhiro Suzumura, Etsuro Hatano, Toshihiro Okada, Jiro Fujimoto
PURPOSE: The purpose of this study was to compare the safety and outcomes of laparoscopic splenic vessel preservation (Lap-SVP) to those of laparoscopic Warshaw technique (Lap-WT). MATERIALS AND METHODS: Fourteen patients underwent Lap-SVP and 5 patients underwent Lap-WT. Their clinical data and outcomes of the 2 procedures were compared. RESULTS: The operative time, intraoperative blood loss, clinically relevant pancreatic fistula, and the rate of splenic infarction were significantly higher in the patients who underwent Lap-WT than in those who underwent Lap-SVP...
October 9, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
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