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https://www.readbyqxmd.com/read/29352532/the-impact-of-severe-mental-disorders-and-psychotropic-medications-on-sexual-health-and-its-implications-for-clinical-management
#1
Angel L Montejo, Laura Montejo, David S Baldwin
Sexual dysfunction often accompanies severe psychiatric illness and can be due to both the mental disorder itself and the use of psychotropic treatments. Many sexual symptoms resolve as the mental state improves, but treatment-related sexual adverse events tend to persist over time, and are unfortunately under-recognized by clinicians and scarcely investigated in clinical trials. Treatment-emergent sexual dysfunction adversely affects quality of life and may contribute to reduce treatment adherence. There are important differences between the various compounds in the incidence of adverse sexual effects, associated with differences in mechanisms of action...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29349764/sexual-function-post-breast-cancer
#2
Lauren Streicher, James A Simon
The consequences of estrogen deprivation and therapeutic interventions such as radiation, chemotherapy and surgery have a significant negative impact on libido, sexual arousal, orgasmic function and the ability to have pleasurable intercourse. Evaluation and treatment of female sexual dysfunction is a significant unmet need in the breast cancer survivor in spite of the availability of safe and effective treatments.
2018: Cancer Treatment and Research
https://www.readbyqxmd.com/read/29341031/getting-more-than-you-paid-for-unauthorized-natural-substances-in-herbal-food-supplements-on-eu-market
#3
Marijana Zovko Končić
As the population in the industrialized world develops preference for what is perceived as a natural and holistic way of disease treatment, the popularity and the number of food supplements on the market, including herbal ones, is experiencing an unprecedented rise. However, unlike herbal medicinal products, intended for treating or preventing disease, current legislation classifies food supplements as products intended for achieving nutritional or physiological effect and to supplement the normal diet. Accordingly, most food supplements are not to be associated with specific health claims...
January 16, 2018: Planta Medica
https://www.readbyqxmd.com/read/29335009/isolated-follicle-stimulated-hormone-deficiency-in-male-case-report
#4
Gowri M Ratnayake, P N Weerathunga, L P Ruwanpura, Amila Wickramasinghe, Prasad Katulanda
BACKGROUND: Recent rapid advances in assisted reproductive health technologies enables couples with subfertility to conceive through various intervention. Majority of treatment modalities target the female partner. However it is important to identify and treat male factor subfertility right at the outset. We report a case of isolated follicle stimulating hormone deficiency resulting in azoospermia and primary subfertility. CASE PRESENTATION: A 28 year otherwise healthy male presented with primary subfertility with a healthy female counterpart...
January 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29313445/body-composition-metabolism-sleep-psychological-and-eating-patterns-of-overtraining-syndrome-results-of-the-eros-study-eros-profile
#5
Flavio A Cadegiani, Claudio E Kater
Overtraining syndrome (OTS) is caused by an imbalance between training, nutrition and resting, and leads to decreased performance and fatigue; however, the precise underlying triggers of OTS remain unclear. This study investigated the body composition, metabolism, eating, sleeping patterns and mood states among participants with OTS. Selected participants were divided into OTS-affected athletes (OTS, n = 14), healthy athletes (ATL, n = 25), and healthy non-physically active controls (NCS, n = 12). Compared to ATL, OTS showed decreased sleep quality (p = 0...
January 9, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29303101/-testosterone-therapy-indications-and-risks
#6
M G F Maatje, M Dinkelman-Smit, W P A Boellaard, G R Dohle
- Late onset hypogonadism (LOH) is a shortage of testosterone in adult men whose male development was normal. This form of hypogonadism results in decreased testosterone levels and variable gonadotrophin levels. - The symptoms of LOH are often aspecific and may be consistent with ageing in men: lowered libido, loss of strength, reduced cognitive functioning and disorders of sleeping and mood. - There is discussion about testosterone parameters, but if clinical symptoms are consistent with LOH and the testosterone level is < 8 nmol/l, hypogonadism is evidently indicated...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29231061/the-effect-of-aqueous-extract-of-rosa-damascena-on-formaldehyde-induced-toxicity-in-mice-testes
#7
Majid Askaripour, Azam Hasanpour, Foruzan Hosseini, Mojgan Moshrefi, Gholamreza Moshtaghi, Mohammad Hasannejad, Soodeh Rajabi, Seyed Noureddin Nematollahi-Mahani
CONTEXT: Rosa damascena L. (Rosaceae) (RD) essential oil and extracts are commonly used as a flavour in herbal medicine which increase libido. Previous studies have shown inhalation of RD flower's oil increases libido and causes protective effects in formaldehyde (FA)-induced testicular damage. OBJECTIVE: The protective effects of aqueous extract of RD on the male reproductive system of mice were examined following FA-induced damage. MATERIALS AND METHODS: Forty-eight adult NMRI male mice were randomly assigned to six groups (n = 8): control (normal saline, 10 mg/kg); RD40 (40 mg/kg, p...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29209693/health-self-perception-in-patient-with-crohn-s-disease-a-web-survey
#8
M Chiarini, E Di Simone, C Scafuro, F Auddino, M Fabbri, A Delli Poggi, S Catanzaro, N Giannetta, M Di Muzio
BACKGROUND: Crohn's Disease (CD) has an incidence on the physical and psychological autonomy of the patient, such as to alter their daily life. The impact of the disease on the daily life of the patients is related to the symptoms and complications of the disease. Patient autonomy and participation in social and work life are the goals that nurses must reach for patients with CD to improve their quality of life. AIM: To measure the perception of the health of people with a diagnosis of CD...
November 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29204279/sellar-plasmacytoma-presenting-with-symptoms-of-anterior-pituitary-dysfunction
#9
Ana G Ferreira, Tiago N Silva, Henrique V Luiz, Filipa D Campos, Maria C Cordeiro, Jorge R Portugal
Sellar plasmacytomas are rare and the differential diagnosis with non-functioning pituitary adenomas might be difficult because of clinical and radiological resemblance. They usually present with neurological signs and intact anterior pituitary function. Some may already have or eventually progress to multiple myeloma. We describe a case associated with extensive anterior pituitary involvement, which is a rare form of presentation. A 68-year-old man was referred to our Endocrinology outpatient clinic due to gynecomastia, reduced libido and sexual impotence...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29198215/dietary-l-arginine-supplementation-improves-semen-quality-and-libido-of-boars-under-high-ambient-temperature
#10
J Q Chen, Y S Li, Z J Li, H X Lu, P Q Zhu, C M Li
l-Arginine is a nutritionally essential amino acid for spermatogenesis and plays versatile roles in animal health and can be utilized as a potential agent to improve reproductive performance of boars under high ambient temperature. The present study aimed to determine whether dietary l-arginine could alleviate heat stress-induced infertility in boars. In all, 20 boars (PIC 1040; 248.59±3.84 kg BW and 407.65±6.40 days of age) were selected and randomly assigned to four groups (group 0.0%, basal diet; group 0...
December 4, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29191197/in-vitro-and-in-vivo-aphrodisiac-properties-of-the-seed-extract-from-allium-tuberosum-on-corpus-cavernosum-smooth-muscle-relaxation-and-sexual-behavior-parameters-in-male-wistar-rats
#11
Xingli Tang, Opeyemi J Olatunji, Yifeng Zhou, Xilin Hou
BACKGROUND: Allium tuberosum is a well-known spice as well as a herb in traditional Chinese medicine, used for increasing libido and treating erectile dysfunction. However, not many studies have been done to evaluate the sexual enhancing properties of A. tuberosum. The aim of this study was to evaluate the aphrodisiac and vasorelaxant properties of A. tuberosum on corpus cavernosum smooth muscle (CCSM) as well as checking the effect on enhancing male rat sexual behavior, libido, potency as well as its spermatogenic properties...
December 1, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29179144/the-centrality-of-dsm-and-non-dsm-depressive-symptoms-in-han-chinese-women-with-major-depression
#12
Kenneth S Kendler, Steven H Aggen, Jonathan Flint, Denny Borsboom, Eiko I Fried
INTRODUCTION: We compared DSM-IV criteria for major depression (MD) with clinically selected non-DSM criteria in their ability to represent clinical features of depression. METHOD: We conducted network analyses of 19 DSM and non-DSM symptoms of MD assessed at personal interview in 5952 Han Chinese women meeting DSM-IV criteria for recurrent MD. We estimated an Ising model (the state-of-the-art network model for binary data), compared the centrality (interconnectedness) of DSM-IV and non-DSM symptoms, and investigated the community structure (symptoms strongly clustered together)...
November 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29177573/triptorelin-a-review-of-its-use-as-an-adjuvant-anticancer-therapy-in-early-breast-cancer
#13
James E Frampton
A 1-month formulation of the gonadotrophin-releasing hormone agonist (GnRHa) triptorelin (Decapeptyl®) has been approved in the EU as an adjuvant treatment in combination with tamoxifen or an aromatase inhibitor (AI), of endocrine-responsive, early-stage breast cancer in women at high risk of recurrence who are confirmed as premenopausal after completion of chemotherapy. This indication reflects the results of the 5-year SOFT and TEXT studies, especially SOFT, in which ovarian function suppression (OFS; mainly achieved with triptorelin) added to tamoxifen provided a significant benefit in the overall study population of premenopausal patients only after adjusting for prognostic factors...
December 2017: Drugs
https://www.readbyqxmd.com/read/29172782/efficacy-of-tribulus-terrestris-for-the-treatment-of-premenopausal-women-with-hypoactive-sexual-desire-disorder-a-randomized-double-blinded-placebo-controlled-trial
#14
Fabiene Bernardes Castro Vale, Karla Zanolla Dias de Souza, Camilla Russi Rezende, Selmo Geber
Although hypoactive sexual desire disorder (HSDD) is the most common sexual complaint, there is no consensus for the ideal treatment. Our study aimed to evaluate the efficacy of treating premenopausal women with HSDD with Tribulus terrestris and its effect on the serum levels of testosterone. We performed a prospective, randomized, double-blind, placebo-controlled trial, with 40 premenopausal women reporting diminished libido, receiving T. terrestris or placebo. The questionnaires FSFI and the QS-F were used to evaluate sexual dysfunction before and after treatment...
November 27, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29171484/-sexual-functioning-and-sexual-dysfunction-in-women-with-infertility
#15
N N Stenyaeva, D F Chritinin, A A Chausov, G T Sukhikh
AIM: To study sexual dysfunction and assess the need in sexological care to improve quality of life of women with infertility. MATERIAL AND METHODS: Sexual functioning was studied in 329 women with infertility and 722 women who underwent an outpatient gynecological examination using a clinical interview and the Female Sexual Function Index (FSFI). RESULTS: In 24.01% of women with infertility, the total FSFI score was correlated with the presence of clinically relevant disorders...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29150464/testosterone-therapy-in-hypogonadal-men-a-systematic-review-and-network-meta-analysis
#16
Jesse Elliott, Shannon E Kelly, Adam C Millar, Joan Peterson, Li Chen, Amy Johnston, Ahmed Kotb, Becky Skidmore, Zemin Bai, Muhammad Mamdani, George A Wells
OBJECTIVE: To assess the relative effects of individual testosterone products among hypogonadal men. DESIGN: Systematic review and network meta-analysis. METHODS: We searched MEDLINE, Embase, Cochrane CENTRAL, and grey literature (25 May 2017) for randomised-controlled trials (RCTs) and non-randomised studies (NRS) that involved hypogonadal men given testosterone replacement therapy (TRT) for ≥3 months. Comparators were placebo, another TRT, or the same product at a different dose...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29105668/-testosterone-replacement-therapy-and-cardiovascular-risk
#17
Giovanni Corona, Mauro Dicuio, Giulia Rastrelli, Alessandra Sforza, Mario Maggi
Late onset hypogonadism (LOH) is the most commonly used term to indicate the age-dependent reduction of testosterone. Sexual dysfunction represents the most important determinant for medical consultation and the most specific symptoms associated with LOH. In particular, data from the European Male Ageing Study (EMAS), a population-based survey on more than 3400 subjects, recognized that a triad of sexual symptoms (low libido and reduced spontaneous and sex-related erections) is the only syndromic association with decreased testosterone levels...
November 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29100664/tyrosine-hydroxylase-in-the-ventral-tegmental-area-of-rams-with-high-or-low-libido-a-role-for-dopamine
#18
A C Kramer, A J Mirto, K J Austin, C E Roselli, B M Alexander
Dopamine synthesis in the ventral tegmental area (VTA) is necessary for the reinforcement of sexual behavior. The objective of this study determined if sexual stimuli initiates reward, and whether reward is attenuated in sexually inactive rams. Sexually active rams were exposed to urine from estrous (n=4) or ovariectomized (n=3) ewes with inactive rams (n=3) exposed to urine from estrous ewes. Following exposure, rams were exsanguinated and brains perfused. Alternating sections of the VTA were stained for Fos related antigens (FRA), tyrosine hydroxylase, and dopamine beta-hydroxylase activity...
October 31, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29095270/pituitary-insufficiency-following-traumatic-thoracic-injury-in-an-adolescent-male-patient-a-case-report-and-literature-review
#19
REVIEW
Aleksandra Gilis-Januszewska, Łukasz Kluczyński, Małgorzata Wilusz, Jacek Pantofliński, Renata Turek-Jabrocka, Dorota Pach, Alicja Hubalewska-Dydejczyk
RATIONALE: Traumatic thoracic injuries in adolescents are rare but could be connected with traumatic brain injuries (TBI) and development of chronic hypopituitarism. Early recognition of these endocrine problems is a significant challenge to clinicians. We present difficulties in diagnosis of hypothalamic-pituitary insufficiency following traumatic thoracic injury in adolescence. We also review the literature of similar cases. PATIENT CONCERNS: We present a case of a 24-years-old male...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29094914/testosterone-therapy-review-of-clinical-applications
#20
REVIEW
Ryan C Petering, Nathan A Brooks
Testosterone therapy is increasingly common in the United States, and many of these prescriptions are written by primary care physicians. There is conflicting evidence on the benefit of male testosterone therapy for age-related declines in testosterone. Physicians should not measure testosterone levels unless a patient has signs and symptoms of hypogonadism, such as loss of body hair, sexual dysfunction, hot flashes, or gynecomastia. Depressed mood, fatigue, decreased strength, and a decreased sense of vitality are less specific to male hypogonadism...
October 1, 2017: American Family Physician
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