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https://www.readbyqxmd.com/read/29220392/safety-and-efficacy-of-the-prepex-device-in-hiv-positive-men-a-single-arm-study-in-zimbabwe
#1
Mufuta Tshimanga, Batsirai Makunike-Chikwinya, Tonderayi Mangwiro, Patricia Tapiwa Gundidza, Pesanai Chatikobo, Vernon Murenje, Amy Herman-Roloff, Peter H Kilmarx, Marrianne Holec, Gerald Gwinji, Owen Mugurungi, Munyaradzi Murwira, Sinokuthemba Xaba, Scott Barnhart, Caryl Feldacker
METHODS: We aimed to determine if the adverse event (AE) rate was non-inferior to an AE rate of 2%, a rate considered the global standard of MC safety. Study procedures, AE definitions, and study staff were unchanged from previous PrePex Zimbabwe trials. After PrePex placement and removal, weekly visits assessed wound healing. Men returned on Day 90. Safety was defined as occurrence of moderate and serious clinical AEs. Efficacy was defined as ability to reach the endpoint of complete circumcision...
2017: PloS One
https://www.readbyqxmd.com/read/29210334/false-beliefs-predict-increased-circumcision-satisfaction-in-a-sample-of-us-american-men
#2
Brian D Earp, Lauren M Sardi, William A Jellison
Critics of non-therapeutic male and female childhood genital cutting claim that such cutting is harmful. It is therefore puzzling that 'circumcised' women and men do not typically regard themselves as having been harmed by the cutting, notwithstanding the loss of sensitive, prima facie valuable tissue. For female genital cutting (FGC), a commonly proposed solution to this puzzle is that women who had part(s) of their vulvae removed before sexual debut 'do not know what they are missing' and may 'justify' their genitally-altered state by adopting false beliefs about the benefits of FGC, while simultaneously stigmatising unmodified genitalia as unattractive or unclean...
December 6, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/29204461/the-association-between-bxo-and-obesity-in-boys-undergoing-circumcision
#3
Molly E Fuchs, Nicholas Beecroft, Daniel G Dajusta, Daryl J McLeod
This study investigated whether boys with balanitis xerotica obliterans (BXO) have increased rates of obesity compared with boys with no concern for BXO (NCB). Boys ≤18 years old with circumcision pathology-confirmed BXO were compared with an age-matched group who had NCB during circumcision. Boys with BXO were found to have a mean body mass index of 70.64 percentile for age compared with 52.43 percentile in age-matched controls (P = .0005). The rate of obesity was significantly higher in boys with BXO (42%) compared with 12...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29191224/i-knew-how-it-feels-but-couldn-t-save-my-daughter-testimony-of-an-ethiopian-mother-on-female-genital-mutilation-cutting
#4
Yohannes Mehretie Adinew, Beza Tamirat Mekete
BACKGROUND: World Health Organization defines female genital mutilation/cutting as all procedures that involve partial or total removal of the external female genitalia, or other injury to the female genital organs for non-medical reasons. The practice is common in Ethiopia, especially among Somali (99%) ethnic groups. Even though FGM/C is labeled illegal practice according to the revised 2005 Penal Code of the country, the practice is still responsible for misery of many girls in Ethiopia...
December 1, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29190263/scale-up-of-voluntary-medical-male-circumcision-services-for-hiv-prevention-12-countries-in-southern-and-eastern-africa-2013-2016
#5
Jonas Z Hines, Onkemetse Conrad Ntsuape, Kananga Malaba, Tiruneh Zegeye, Kennedy Serrem, Elijah Odoyo-June, Rose Kolola Nyirenda, Wezi Msungama, Kondwani Nkanaunena, Jotamo Come, Marcos Canda, Herminio Nhaguiombe, Ella K Shihepo, Brigitte L T Zemburuka, Gram Mutandi, Emmanuel Yoboka, André H Mbayiha, Hilda Maringa, Alfred Bere, J Joseph Lawrence, Gissenge J I Lija, Daimon Simbeye, Kokuhumbya Kazaura, Ramadhani S Mwiru, Stella Alamo Talisuna, Joseph Lubwama, Geoffrey Kabuye, James Exnobert Zulu, Omega Chituwo, Maybin Mumba, Sinokuthemba Xaba, John Mandisarisa, Brittney N Baack, Lawrence Hinkle, Jonathan M Grund, Stephanie M Davis, Carlos Toledo
Countries in Southern and Eastern Africa have the highest prevalence of human immunodeficiency virus (HIV) infection in the world; in 2015, 52% (approximately 19 million) of all persons living with HIV infection resided in these two regions.* Voluntary medical male circumcision (VMMC) reduces the risk for heterosexually acquired HIV infection among males by approximately 60% (1). As such, it is an essential component of the Joint United Nations Programme on HIV/AIDS (UNAIDS) strategy for ending acquired immunodeficiency syndrome (AIDS) by 2030 (2)...
December 1, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29188391/bisexual-and-bidirectional-assessing-the-potential-for-hiv-bridging-in-mozambique
#6
Beverley Cummings, Roberta Horth, Willi McFarland, Tim Lane, Peter W Young, Rassul Nalá, George Rutherford, H Fisher Raymond
African men who have sex with men (MSM) frequently, and often concurrently, have female partners, raising concerns about HIV sexual bridging. We explored potential HIV transmission in Mozambique from and to female partners of MSM focusing on preferred anal sex role and circumcision status. Data collected in a respondent-driven sampling study of MSM in 2011 in Maputo and Beira. Men who had oral or anal sex with other men 12 months prior completed a questionnaire and consented for HIV testing. Statistical analysis explored demographic/risk characteristics and associations among circumcision status, anal sex with men, sexual positions during anal sex with men and vaginal or anal sex with women...
November 29, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29184774/updates-on-the-epidemiology-and-risk-factors-for-penile-cancer
#7
REVIEW
Antoin Douglawi, Timothy A Masterson
Penile cancer is a rare neoplasm representing less than 1% of all malignancies in the USA and Europe but is a significant public health hazard in the developing world. Male neonatal circumcision has been associated with a dramatic decrease in penile cancer rates with countries such as Israel, where circumcision is widely performed, having the lowest incidence in the world at <0.1% of malignancies. Many risk factors have been identified for penile cancer including phimosis, lack of circumcision, obesity, lichen sclerosis, chronic inflammation, smoking, UVA phototherapy, socioeconomic status, human papillomavirus (HPV) infection and immune compromised states...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29173273/incidence-of-bleeding-in-children-undergoing-circumcision-with-ketorolac-administration
#8
Bruce Gao
INTRODUCTION: Circumcision is the most common surgical procedure performed by pediatric urologists. Ketorolac has been shown to have an efficacy similar to morphine in multimodal analgesic regimens without the commonly associated adverse effects. Concerns with perioperative bleeding limit the use of ketorolac as an adjunct for pain control in surgical patients. As such, we sought to evaluate our institutional outcomes with respect to ketorolac and postoperative bleeding. METHODS: We retrospectively reviewed all pediatric patients undergoing circumcision from January 1, 2014 to December 31, 2015 at the Alberta Children's Hospital...
December 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29171817/hiv-prevention-efforts-and-incidence-of-hiv-in-uganda
#9
M Kate Grabowski, David M Serwadda, Ronald H Gray, Gertrude Nakigozi, Godfrey Kigozi, Joseph Kagaayi, Robert Ssekubugu, Fred Nalugoda, Justin Lessler, Thomas Lutalo, Ronald M Galiwango, Fred Makumbi, Xiangrong Kong, Donna Kabatesi, Stella T Alamo, Steven Wiersma, Nelson K Sewankambo, Aaron A R Tobian, Oliver Laeyendecker, Thomas C Quinn, Steven J Reynolds, Maria J Wawer, Larry W Chang
BACKGROUND: To assess the effect of a combination strategy for prevention of human immunodeficiency virus (HIV) on the incidence of HIV infection, we analyzed the association between the incidence of HIV and the scale-up of antiretroviral therapy (ART) and medical male circumcision in Rakai, Uganda. Changes in population-level viral-load suppression and sexual behaviors were also examined. METHODS: Between 1999 and 2016, data were collected from 30 communities with the use of 12 surveys in the Rakai Community Cohort Study, an open, population-based cohort of persons 15 to 49 years of age...
November 30, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29170049/brachytherapy-for-conservative-treatment-of-invasive-penile-carcinoma-in-older-patients-single-institution-experience
#10
Alexandre Escande, Pierre Maroun, Isabelle Dumas, Antoine Schernberg, Alberto Bossi, Renaud De Crevoisier, Eric Deutsch, Christine Haie-Meder, Cyrus Chargari
BACKGROUND: No study has examined the possibility to perform an organ sparing strategy in older patients with penile carcinoma, and amputation is frequently proposed. We report our experience of interstitial brachytherapy for the conservative treatment of penile carcinoma confined to the glans in patients aged of 70years and more. METHODS: A total of 55 patients candidates to conservative brachytherapy were identified. Median age was 73.8years (range: 70-95years)...
November 20, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29161549/ultrasound-guided-versus-conventional-injection-for-caudal-block-in-children-a-prospective-randomized-clinical-study
#11
Ali Ahiskalioglu, Ahmet Murat Yayik, Elif Oral Ahiskalioglu, Mursel Ekinci, Birzat Emre Gölboyu, Erkan Cem Celik, Haci Ahmet Alici, Akgun Oral, Saban Oguz Demirdogen
STUDY OBJECTIVE: The aim of this study was to compare the efficacies of ultrasound guided sacral hiatus injection and conventional sacral canal injection performed for caudal block in children. DESIGN: Randomized controlled clinical trial. SETTING: Operating rooms of university hospital of Erzurum, Turkey. PATIENTS: One hundred-thirty four children, American Society of Anesthesiologists I-II, between the ages of 5 and 12, scheduled for elective phimosis and circumcision surgery...
November 18, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29150460/ring-block-of-the-penis-a-proven-addition-to-multimodal-pain-relief-for-newborn-circumcision
#12
David A Rosen, Lynn M Broadman
No abstract text is available yet for this article.
November 17, 2017: Pediatrics
https://www.readbyqxmd.com/read/29150457/combination-analgesia-for-neonatal-circumcision-a-randomized-controlled-trial
#13
Rana Sharara-Chami, Zavi Lakissian, Lama Charafeddine, Nadine Milad, Yaser El-Hout
OBJECTIVES: There is no consensus on the most effective pain management for neonatal circumcision. We sought to compare different modalities. METHODS: This is a double-blinded randomized controlled trial comparing 3 combination analgesics used during circumcision (EMLA + sucrose; EMLA + sucrose + dorsal penile nerve block [DPNB]; EMLA + sucrose + ring block [RB]) with the traditional topical analgesic cream EMLA alone. The trial was set in the normal nursery of a teaching hospital...
November 17, 2017: Pediatrics
https://www.readbyqxmd.com/read/29148634/labor-delivery-and-postpartum-complications-in-nulliparous-women-with-female-genital-mutilation-admitted-to-karamara-hospital
#14
Wondimu Gudu, Mutasim Abdulahi
Objectives: To assess labor, delivery and postpartum complications in nulliparous women with FGM/C and evaluate the attitude of mothers towards elimination of FGM. Methods: A prospective hospital based study using structured questionnaire was conducted between January to March 2015 at Karamara hospital, Jijiga, Ethiopia. All nulliparous women admitted for labor and delivery were included. Data were collected regarding circumcision status, events of labor, delivery; postpartum and neonatal outcomes as well as attitude of mothers towards elimination of FGM/C...
January 2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/29147059/tetanus-in-adult-males-bugando-medical-centre-united-republic-of-tanzania
#15
Riaz Aziz, Robert N Peck, Samuel Kalluvya, Bernard Kenemo, Alphonce Chandika, Jennifer A Downs
Problem: In the United Republic of Tanzania, the incidence of non-neonatal circumcision-related tetanus is probably underreported. Approach: We analysed charts and extracted information on outcome and wound location for non-neonatal cases of tetanus admitted to the intensive care unit of Bugando Medical Centre between 2001 and 2016. Local setting: Bugando Medical Centre, which is one of four teaching referral hospitals in the United Republic of Tanzania, has a 13-bed intensive care unit that manages all admitted patients with tetanus...
November 1, 2017: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29138139/gp-avoids-prosecution-over-circumcision-of-3-month-old-baby
#16
Clare Dyer
No abstract text is available yet for this article.
November 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29136009/early-resumption-of-sexual-activity-following-voluntary-medical-male-circumcision-in-botswana-a-qualitative-study
#17
Jenny H Ledikwe, Nankie M Ramabu, Lisa P Spees, Scott Barnhart, Conrad Ntsuape, Bazghina-Werq Semo, Kathleen E Wirth
Unprotected sexual intercourse after undergoing voluntary medical male circumcision but prior to complete wound healing can lead to major adverse events including HIV acquisition. To better understand perceptions related to early resumption of sex prior to wound healing, 27 focus group discussions were conducted among 238 adult men, women, and community leaders in Botswana. Median age among all participants was 31 years of whom 60% were male and 51% were either employed and receiving salary or self-employed...
2017: PloS One
https://www.readbyqxmd.com/read/29132984/penile-sparing-surgery-for-penile-cancer-a-multicenter-international-retrospective-cohort
#18
Adam Baumgarten, Juan Chipollini, Sylvia Yan, Sarah R Ottenhof, Dominic H Tang, Désirée Draeger, Chris Protzel, Yao Zhu, Ding-Wei Ye, Oliver W Hakenberg, Simon Horenblas, Nicholas A Watkin, Philippe E Spiess
PURPOSE: To evaluate recurrence outcomes of penile sparing surgery (PSS) in the largest multicenter cohort of patients to date. METHODS: We retrospectively identified patients treated with PSS from May 1990 to July 2016 at five tertiary referral institutions. Treatments consisted of circumcision, wide local excision, laser therapy with or without local excision, partial or total glansectomy, and glans resurfacing. Primary endpoint was local recurrence free survival (LRFS) and defined from initial treatment to time of local recurrence and estimated with the Kaplan-Meier method...
November 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29132483/glanular-hypospadias-management-with-modified-circumcision-and-firlit-procedure
#19
Nadeem Iqbal, Ijaz Hussain, Muneeb Ahmad Cheema, Muhammad Taimur Hijazi, Meherunnisa Asif Khan, Omair Ul Haq Lodhi, Saeed Akhter
OBJECTIVE: To document the results of using simple technique of Firlit procedure with modified circumcision for treatment of glanular hypospadias. STUDY DESIGN: Descriptive case series. PLACE AND DURATION OF STUDY: Department of Urology, Shifa International Hospital, Islamabad, from January 2011 till May 2017. METHODOLOGY: The subjects included pediatric patients who underwent repair of glanular hypospadias by using modified circumcision and Firlit procedure...
November 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29124248/circumcision-incision-orchidopexy-a-novel-technique-for-palpable-low-inguinal-undescended-testis
#20
Michael E Chua, Jan Michael A Silangcruz, Odina Gomez, Jun S Dy, Marcelino L Morales
Given that both orchidopexy and circumcision are commonly done in a single operative setting, we adopted a technique of combined orchidopexy and circumcision using a single circumcision incision. We applied this new technique to boys with palpable, low inguinal cryptorchidism. Here we describe a case series of 7 boys who underwent concurrent orchidopexy via the circumcision site. We present this novel technique and discuss our preliminary outcomes, including the anatomic basis and feasibility. The technique appears to be an alternative for concurrent circumcision and cryptorchid cases with palpable, low inguinal testes...
November 2017: Investigative and Clinical Urology
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