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https://www.readbyqxmd.com/read/28714809/reticence-in-disclosure-of-hiv-infection-and-reasons-for-bereavement-impact-on-perinatally-infected-adolescents-mental-health-and-understanding-of-hiv-treatment-and-prevention-in-johannesburg-south-africa
#1
Nataly Woollett, Vivian Black, Lucie Cluver, Heena Brahmbhatt
Survival rates of perinatally infected HIV-positive adolescents (PIA) are increasing in sub-Saharan Africa. There is a gap in understanding how disclosure and bereavement have an impact on PIA beliefs and understanding of their HIV infection and its management. In-depth interviews were conducted with 25 purposively selected adolescents aged 13-19 years from 5 public health clinics in Johannesburg, South Africa. Data were analysed using NVivo 10 using a thematic approach. PIA experience incomplete disclosure both of their HIV status and reasons for their bereavements, which limits their understanding of how they became infected, vertical transmission and prevention options like prevention of mother-to-child transmission (PMTCT)...
July 17, 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28707345/the-cascade-of-care-to-prevent-mother-to-child-transmission-in-rio-de-janeiro-brazil-1996-2013-improving-but-still-some-way-to-go
#2
Cristina Barroso Hofer, Matthias Egger, Mary-Ann Davies, Ana Cristina Cisne Frota, Ricardo Hugo de Oliveira, Thalita Fernandes Abreu, Lúcia Evangelista Araújo, Bernardo Bastos Witthlin, Alice Weber Carvalho, Janaína Rivas Cordeiro, Giulia Pasqualini Lima, Olivia Keiser
OBJECTIVE: To describe the cascade of care to HIV mother-to-child-transmission (PMTCT) in a Rio de Janeiro reference pediatric clinic, and evaluate the main factors possibly associated with HIV transmission. METHODS: Data on antenatal care, perinatal and neonatal assistance to HIV-infected and HIV-exposed but uninfected children assisted in the clinic from 1996-2013 were collected. The cascade of care was graphically demonstrated, and possible factors associated with HIV infection were described using regression models for bivariate and multivariate analysis...
July 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28705148/correlates-of-facility-delivery-for-rural-hiv-positive-pregnant-women-enrolled-in-the-moment-nigeria-prospective-cohort-study
#3
Nadia A Sam-Agudu, Christopher Isah, Chinenye Fan-Osuala, Salome Erekaha, Habib O Ramadhani, Udochisom Anaba, Olusegun A Adeyemi, Grace Manji-Obadiah, Daniel Lee, Llewellyn J Cornelius, Manhattan Charurat
BACKGROUND: Low rates of maternal healthcare service utilization, including facility delivery, may impede progress in the prevention of mother-to-child transmission of HIV (PMTCT) and in reducing maternal and infant mortality. The MoMent (Mother Mentor) study investigated the impact of structured peer support on early infant diagnosis presentation and postpartum maternal retention in PMTCT care in rural Nigeria. This paper describes baseline characteristics and correlates of facility delivery among MoMent study participants...
July 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28704472/prevention-of-mother-to-child-transmission-of-hiv-option-b-cascade-in-rural-tanzania-the-one-stop-clinic-model
#4
Anna Gamell, Lameck Bonaventure Luwanda, Aneth Vedastus Kalinjuma, Leila Samson, Alex John Ntamatungiro, Maja Weisser, Winfrid Gingo, Marcel Tanner, Christoph Hatz, Emilio Letang, Manuel Battegay
BACKGROUND: Strategies to improve the uptake of Prevention of Mother-To-Child Transmission of HIV (PMTCT) are needed. We integrated HIV and maternal, newborn and child health services in a One Stop Clinic to improve the PMTCT cascade in a rural Tanzanian setting. METHODS: The One Stop Clinic of Ifakara offers integral care to HIV-infected pregnant women and their families at one single place and time. All pregnant women and HIV-exposed infants attended during the first year of Option B+ implementation (04/2014-03/2015) were included...
2017: PloS One
https://www.readbyqxmd.com/read/28696347/building-health-system-capacity-through-implementation-research-experience-of-inspire-a-multi-country-pmtct-implementation-research-project-erratum
#5
(no author information available yet)
No abstract text is available yet for this article.
August 15, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28693525/baseline-characteristics-of-study-sites-and-women-enrolled-in-a-three-arm-cluster-randomized-controlled-trial-pmtct-uptake-and-retention-pure-malawi
#6
Monique van Lettow, Hannock Tweya, Nora E Rosenberg, Clement Trapence, Virginia Kayoyo, Florence Kasende, Blessings Kaunda, Mina C Hosseinipour, Michael Eliya, Fabian Cataldo, Salem Gugsa, Sam Phiri
BACKGROUND: Malawi introduced an ambitious public health program known as "Option B+" which provides all HIV-infected pregnant and breastfeeding women with lifelong combination antiretroviral therapy, regardless of WHO clinical stage or CD4 cell count. The PMTCT Uptake and REtention (PURE) study aimed at evaluating the effect of peer-support on care-seeking and retention in care. METHODS/DESIGN: PURE Malawi was a three-arm cluster randomized controlled trial that compared facility-based and community-based models of peer support to standard of care under Option B+ strategy...
July 11, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28683718/rate-of-hiv-transmission-and-associated-factors-among-hiv-exposed-infants-in-selected-health-facilities-of-east-and-west-gojjam-zones-northwest-ethiopia-retrospective-cohort-study
#7
Nurilign Abebe Moges, Getachew Mullu Kassa, Dube Jara Boneya
BACKGROUND: In 2014, there were 170,000 new HIV-infected children globally. The rate of HIV transmission from mother to child in Ethiopia was 18%. Though there are a number of HIV-related studies conducted in Ethiopia, there is a scarcity of evidence on the rate of mother to child transmission. So, the aim of this study was to determine the rate of HIV transmission and associated factors among HIV-exposed infants in selected health facilities in East and West Gojjam Zones, Northwest Ethiopia...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28679418/transitioning-from-antenatal-surveillance-surveys-to-routine-hiv-testing-a-turning-point-in-the-mother-to-child-transmission-prevention-programme-for-hiv-surveillance-in-brazil
#8
Gerson Fernando Mendes Pereira, Meritxell Sabidó, Alessandro Caruso, Adele Schwartz Benzaken
BACKGROUND: In Brazil, due to the rapid increase in programmes for the prevention of mother-to-child transmission (PMTCT), routine programme data are widely available. The objective of this study was to assess the utility of programmatic data to replace HIV surveillance based on the antenatal care (ANC) surveillance survey (SS). METHODS: We analysed ANC SS data from 219 maternity service clinics. PMTCT variables were extracted from the ANC SS data collection form, which allowed us to capture and compare the ANC SS data and PMTCT HIV test results for each pregnant woman who completed the ANC SS...
July 5, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28655683/integration-of-prevention-of-mother-to-child-hiv-transmission-into-maternal-health-services-in-senegal
#9
C Cisse
The objective of this study was to assess the level of integration of prevention of mother-to-child HIV transmission (PMTCT) in facilities providing services for maternal, newborn, and child health (MNCH) and reproductive health (RH) in Senegal. The survey, conducted from August through November, 2014, comprised five parts : a literature review to assess the place of this integration in the health policies, standards, and protocols in effect in Senegal; an analysis by direct observation of attitudes and practices of 25 healthcare providers at 5 randomly-selected obstetrics and gynecology departments representative of different levels of the health pyramid; a questionnaire evaluating knowledge and attitudes of 10 providers about the integration of PMTCT services into MNCH/RH facilities; interviews to collect the opinions of 70 clients, including 16 HIV-positive, about the quality of PMTCT services they received; and a questionnaire evaluating knowledge and opinions of 14 policy-makers/managers of health programs focusing on mothers and children about this integration...
June 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28655314/greater-involvement-of-hiv-infected-peer-mothers-in-provision-of-reproductive-health-services-as-family-planning-champions-increases-referrals-and-uptake-of-family-planning-among-hiv-infected-mothers
#10
Peter Mudiope, Ezra Musingye, Carolyne Onyango Makumbi, Danstan Bagenda, Jaco Homsy, Mai Nakitende, Mike Mubiru, Linda Barlow Mosha, Mike Kagawa, Zikulah Namukwaya, Mary Glenn Fowler
BACKGROUND: In 2012, Makerere University Johns - Hopkins University, and Mulago National Referral Hospital, with support from the National Institute of Health (under Grant number: NOT AI-01-023) undertook operational research at Mulago National Hospital PMTCT/PNC clinics. The study employed Peer Family Planning Champions to offer health education, counselling, and triage aimed at increasing the identification, referral and family planning (FP) uptake among HIV positive mothers attending the clinic...
June 27, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28650382/hiv-drug-resistance-in-infants-increases-with-changing-pmtct-regimens
#11
Lisa K Poppe, Catherine Chunda-Liyoka, Eun Hee Kwon, Clement Gondwe, John T West, Chipepo Kankasa, Clement B Ndongmo, Charles Wood
OBJECTIVES: The objectives of this study were to determine HIV drug resistance prevalence in Zambian infants upon diagnosis, and to determine how changing prevention of mother-to-child transmission (PMTCT) regimens affect drug resistance. DESIGN: Dried blood spot (DBS) samples from infants in the Lusaka District of Zambia, obtained during routine diagnostic screening, were collected during four different years representing three different PMTCT treatment regimens...
June 23, 2017: AIDS
https://www.readbyqxmd.com/read/28646888/utilization-of-hiv-testing-services-among-pregnant-mothers-in-low-income-primary-care-settings-in-northern-ethiopia-a-cross-sectional-study
#12
Yihun Mulugeta Alemu, Fentie Ambaw, Annelies Wilder-Smith
BACKGROUND: HIV testing of women in child bearing age is an entry point for preventing mother-to-child transmission of HIV (MTCT). This study aims to identify the proportion of women tested for HIV and to determine factors associated with utilization of HIV testing services among pregnant mothers in primary care settings in northern Ethiopia. METHODS: A cross sectional study was conducted in 416 pregnant women from four primary care centers between October 2, 2012 and May 31, 2013 in East Gojjam, Ethiopia...
June 24, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28626358/psychosocial-correlates-of-patient-provider-family-planning-discussions-among-hiv-infected-pregnant-women-in-south-africa
#13
Violeta J Rodriguez, Ryan R Cook, Stephen M Weiss, Karl Peltzer, Deborah L Jones
Patient-provider family planning discussions and preconception counseling can reduce maternal and neonatal risks by increasing adherence to provider recommendations and antiretroviral medication. However, HIV-infected women may not discuss reproductive intentions with providers due to anticipation of negative reactions and stigma. This study aimed to identify correlates of patient-provider family planning discussions among HIV-infected women in rural South Africa, an area with high rates of antenatal HIV and suboptimal rates of prevention of mother-to-child transmission (PMTCT) of HIV...
2017: Open Access J Contracept
https://www.readbyqxmd.com/read/28594842/-if-my-husband-leaves-me-i-will-go-home-and-suffer-so-better-cling-to-him-and-hide-this-thing-the-influence-of-gender-on-option-b-prevention-of-mother-to-child-transmission-participation-in-malawi-and-uganda
#14
Valerie L Flax, Jennifer Yourkavitch, Elialilia S Okello, John Kadzandira, Anne Ruhweza Katahoire, Alister C Munthali
The role of gender in prevention of mother-to-child transmission (PMTCT) participation under Option B+ has not been adequately studied, but it is critical for reducing losses to follow-up. This study used qualitative methods to examine the interplay of gender and individual, interpersonal, health system, and community factors that contribute to PMTCT participation in Malawi and Uganda. We conducted in-depth interviews with women in PMTCT, women lost to follow-up, government health workers, and stakeholders at organizations supporting PMTCT as well as focus group discussions with men...
2017: PloS One
https://www.readbyqxmd.com/read/28582993/mapping-evidence-of-interventions-and-strategies-to-bridge-the-gap-in-the-implementation-of-the-prevention-of-mother-to-child-transmission-of-hiv-programme-policy-in-sub-saharan-countries-a-scoping-review
#15
Wilbroda H Ngidi, Joanne R Naidoo, Busisiwe P Ncama, Zamasomi P B Luvuno, Tivani P Mashamba-Thompson
BACKGROUND: Prevention of mother-to-child transmission (PMTCT) of HIV is a life-saving public health intervention. Sub-Saharan African (SSA) countries have made significant progress in the programme, but little is known about the strategies used by them to eliminate mother-to-child transmission of HIV. AIM: To map evidence of strategies and interventions employed by SSA in bridging the implementation gap in the rapidly changing PMTCT of HIV programme policy. METHODS: Electronic search of the databases MEDLINE, PubMed and SABINET for articles published in English between 2001 and August 2016...
May 29, 2017: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/28578686/challenges-and-opportunities-of-optimal-breastfeeding-in-the-context-of-hiv-option-b-guidelines
#16
Pamela Marinda, Nkandu Chibwe, Ernest Tambo, Sidney Lulanga, Christopher Khayeka-Wandabwa
BACKGROUND: In 2013, the World Health Organization released a new set of guidelines widely known as Option B+. Prior to that there were guidelines released in 2010. Option B+ recommends lifelong antiretroviral treatment for all pregnant and breastfeeding women living with Human Immunodeficiency Virus. The study aimed at investigating challenges and opportunities in implementing Infant and Young Child Feeding in the context of Prevention of Mother To Child Transmission (PMTCT) guidelines among HIV positive mothers of children aged 0-24 months...
June 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28567281/toward-elimination-of-mother-to-child-transmission-of-hiv-in-south-africa-how-best-to-monitor-early-infant-infections-within-the-prevention-of-mother-to-child-transmission-program
#17
Gayle G Sherman, Ahmad Haeri Mazanderani, Peter Barron, Sanjana Bhardwaj, Ronelle Niit, Margaret Okobi, Adrian Puren, Debra J Jackson, Ameena Ebrahim Goga
BACKGROUND: South Africa has utilized three independent data sources to measure the impact of its program for the prevention of mother-to-child transmission (PMTCT) of HIV. These include the South African National Health Laboratory Service (NHLS), the District Health Information System (DHIS), and South African PMTCT Evaluation (SAPMTCTE) surveys. We compare the results of each, outlining advantages and limitations, and make recommendations for monitoring transmission rates as South Africa works toward achieving elimination of mother-to-child transmission (eMTCT)...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28562612/decreased-emergence-of-hiv-1-drug-resistance-mutations-in-a-cohort-of-ugandan-women-initiating-option-b-for-pmtct
#18
Patrycja Machnowska, Andrea Hauser, Karolin Meixenberger, Britta Altmann, Norbert Bannert, Eva Rempis, Alexandra Schnack, Sarah Decker, Vera Braun, Priscilla Busingye, John Rubaihayo, Gundel Harms, Stefanie Theuring
BACKGROUND: Since 2012, WHO guidelines for the prevention of mother-to-child transmission (PMTCT) of HIV-1 in resource-limited settings recommend the initiation of lifelong antiretroviral combination therapy (cART) for all pregnant HIV-1 positive women independent of CD4 count and WHO clinical stage (Option B+). However, long-term outcomes regarding development of drug resistance are lacking until now. Therefore, we analysed the emergence of drug resistance mutations (DRMs) in women initiating Option B+ in Fort Portal, Uganda, at 12 and 18 months postpartum (ppm)...
2017: PloS One
https://www.readbyqxmd.com/read/28549434/the-potential-of-task-shifting-in-scaling-up-services-for-prevention-of-mother-to-child-transmission-of-hiv-a-time-and-motion-study-in-dar-es-salaam-tanzania
#19
Helga Naburi, Anna Mia Ekström, Phares Mujinja, Charles Kilewo, Karim Manji, Gunnel Biberfeld, David Sando, Guerino Chalamila, Till Bärnighausen
BACKGROUND: In many African countries, prevention of mother-to-child transmission of HIV (PMTCT) services are predominantly delivered by nurses. Although task-shifting is not yet well established, community health workers (CHWs) are often informally used as part of PMTCT delivery. According to the 2008 World Health Organization (WHO) Task-shifting Guidelines, many PMTCT tasks can be shifted from nurses to CHWs. METHODS: The aim of this time and motion study in Dar es Salaam, Tanzania, was to estimate the potential of task-shifting in PMTCT service delivery to reduce nurses' workload and health system costs...
May 26, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28542359/performance-evaluation-of-bd-facspresto%C3%A2-point-of-care-cd4-analyzer-to-enumerate-cd4-counts-for-monitoring-hiv-infected-individuals-in-nigeria
#20
Olubunmi Ruth Negedu-Momoh, Feyisayo Ebenezer Jegede, Ali Yakubu, Oluseyi Balogun, Musa Abdullahi, Titilope Badru, Edward Adekola Oladele, Chinedu Agbakwuru, Hadiza Khamofu, Kwasi Torpey
BACKGROUND: Despite the upsurge in support and intervention of donor agencies in HIV care and treatment programing in Sub-Sahara African, antiretroviral (ART) programs are still confronted with access and coverage challenges which influence enrolment of new patients. This study investigated the validity of point of care BD FACSPresto™ CD4 analyzer for CD4+ cell count, overall agreement, correlation, sensitivity, and specificity in comparison to a reference standard flow cytometry method...
2017: PloS One
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