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https://www.readbyqxmd.com/read/29391055/she-knows-that-she-will-not-come-back-tracing-patients-and-new-thresholds-of-collective-surveillance-in-pmtct-option-b
#1
Fabian Cataldo, Janet Seeley, Misheck J Nkhata, Zivai Mupambireyi, Edward Tumwesige, Diana M Gibb
BACKGROUND: Malawi, Uganda, and Zimbabwe have recently adopted a universal 'test-and-treat' approach to the prevention of mother-to-child transmission of HIV (Option B+). Amongst a largely asymptomatic population of women tested for HIV and immediately started on antiretroviral treatment (ART), a relatively high number are not retained in care; they are labelled 'defaulters' or 'lost-to-follow-up' patients. METHODS: We draw on data collected as part of a study looking at ART decentralization (Lablite) to reflect on the spaces created through the instrumentalization of community health workers (CHWs) for the purpose of bringing women who default from Option B+ back into care...
February 1, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29383588/investigation-of-the-effects-of-a-prevention-of-mother-to-child-hiv-transmission-program-among-iranian-neonates
#2
Farah Bokharaei-Salim, Saeed Kalantari, Zahra Gholamypour, AliReza Najafi, Hossein Keyvani, Maryam Esghaei, Seyed Hamidreza Monavari, Khadijeh Khanaliha, Mohammad-Navid Bastani, Atousa Fakhim, Saba Garshasbi
Human immunodeficiency virus (HIV) infection is mostly spreading in developing countries. One of the most important pathways of HIV infection in these nations is the vertical route, from mother to infant. Therefore, this study evaluated the effectiveness of the prevention of mother-to-child transmission (PMTCT) program for HIV among Iranian neonates born to HIV-positive mothers. A total of 54 neonates born to HIV-1 positive mothers, all of whom were in a PMTCT program for HIV, as per the Iranian guidelines, were enrolled in this descriptive cross sectional study from March 2014 to July 2017...
January 30, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29378622/maximizing-adherence-and-retention-for-women-living-with-hiv-and-their-infants-in-kenya-motivate-study-study-protocol-for-a-randomized-controlled-trial
#3
Thomas A Odeny, Maricianah Onono, Kevin Owuor, Anna Helova, Iris Wanga, Elizabeth A Bukusi, Janet M Turan, Lisa L Abuogi
BACKGROUND: Successful completion and retention throughout the multi-step cascade of prevention of mother-to-child HIV transmission (PMTCT) remains difficult to achieve. The Mother and Infant Visit Adherence and Treatment Engagement study aims to evaluate the effect of mobile text messaging, community-based mentor mothers (cMMs), or both on increasing antiretroviral therapy (ART) adherence, retention in HIV care, maternal viral load suppression, and mother-to-child HIV transmission for mother-infant pairs receiving lifelong ART...
January 29, 2018: Trials
https://www.readbyqxmd.com/read/29364979/navigating-the-risks-of-prevention-of-mother-to-child-transmission-pmtct-of-hiv-services-in-kibera-kenya-barriers-to-engaging-and-remaining-in-care
#4
Kerry A Thomson, Barbara Telfer, Patricia Opondo Awiti, Jane Munge, Mathew Ngunga, Anthony Reid
Within the first year of implementation, 43% of women who tested HIV positive at their first antenatal care visit were no longer retained and being followed in the free prevention of mother to child transmission (PMTCT) of HIV program offered by the Kenyan Ministry of Health and Médecins Sans Frontières in the informal settlement of Kibera, Nairobi. This study aimed to explore barriers to enrolling and remaining engaged in PMTCT services throughout the pregnancy and postpartum periods. Qualitative data from 31 focus group discussions and 35 in-depth interviews across six stakeholder groups that included women, men, and PMTCT service providers were analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29364404/-prevention-of-maternal-child-transmission-of-hiv-in-pregnant-women-and-mothers-of-the-awajun-and-wampis-communities-in-the-amazon-region-of-peru
#5
Byelca Huamán, Alfonso Gushiken, Carlos Benites, Fabiola Quiroz, Lisset García-Fernández
OBJECTIVES: To identify the barriers that limit compliance with the prevention of mother-to-child transmission (PMTCT) of HIV measures in two indigenous communities of the Amazon region of Peru. MATERIALS AND METHODS: Qualitative study with a phenomenological approach. Semi-structured interviews were conducted with pregnant women and mothers of children younger than 1 year of the awajún and wampis indigenous communities diagnosed with HIV in the period 2014-2015...
October 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29356763/temporal-improvements-in-long-term-outcome-in-care-among-hiv-infected-children-enrolled-in-public-art-care-an-analysis-of-outcomes-from-2004-2012-in-zimbabwe
#6
A Tariro Makadzange, Leanne Dougherty, Rutendo Birri, Gillian Kupakuwana, Janneke van Dijk, Mutsa Bwakura Dangarembizi, Nomvuyo Mothobi, Benjamin Phelps, Bisola Ojikutu, Chiratidzo E Ndhlovu
INTRODUCTION: Increasing numbers of children are requiring long-term HIV care and antiretroviral treatment (ART) in public ART programs in Africa but temporal trends and long-term outcomes in care remain poorly understood. METHODS: We analyzed outcomes in a longitudinal cohort of infants (<2 years) and children (2-10 years) enrolling in a public tertiary ART center in Zimbabwe over an eight-year period (2004-2012). RESULTS: The clinic enrolled 1644 infants and children; the median age at enrollment was 39 months (IQR 14-79), with a median CD4% of 17...
January 18, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29351639/call-to-action-prevention-of-mother-to-child-transmission-of-hepatitis-b-in-africa
#7
Peyton Wilson, Jonathan B Parr, Ravi Jhaveri, Steve R Meshnick
Hepatitis B virus (HBV) is a significant public health issue that has not been adequately addressed, especially in the high-prevalence region of Africa. Despite the incorporation of HBV vaccines into the Expanded Program on Immunization (EPI), children continue to be infected with HBV through maternal-to-child transmission (MTCT). The addition of a birth dose of HBV vaccine would be a cost-effective method to reduce MTCT. Birth-dose HBV vaccine policies have been adopted in the Western Pacific region but have yet to be implemented in the African region...
January 17, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29351561/preconception-use-of-cart-by-hiv-positive-pregnant-women-increases-the-risk-of-infants-being-born-small-for-gestational-age
#8
Ingrid J M Snijdewind, Colette Smit, Mieke H Godfried, Rachel Bakker, Jeannine F J B Nellen, Vincent W V Jaddoe, Elisabeth van Leeuwen, Peter Reiss, Eric A P Steegers, Marchina E van der Ende
BACKGROUND: The benefits of combination anti-retroviral therapy (cART) in HIV-positive pregnant women (improved maternal health and prevention of mother to child transmission [pMTCT]) currently outweigh the adverse effects due to cART. As the variety of cART increases, however, the question arises as to which type of cART is safest for pregnant women and women of childbearing age. We studied the effect of timing and exposure to different classes of cART on adverse birth outcomes in a large HIV cohort in the Netherlands...
2018: PloS One
https://www.readbyqxmd.com/read/29335920/clergy-s-beliefs-about-mental-illness-and-their-perception-of-its-treatability-experience-from-a-church-based-prevention-of-mother-to-child-hiv-transmission-pmtct-trial-in-nigeria
#9
Theddeus Iheanacho, Elina Stefanovics, Echezona E Ezeanolue
Clergy participating in the Healthy Beginning Initiative (N = 45), a program utilizing church workers to integrate packages of care into church activities, completed a 43-item self-administered questionnaire assessing their attitudes and beliefs about mental disorders and perception of their treatability. A majority believed that drug/alcohol use, stress and genetic inheritance could cause mental illness and that society needed to adopt more tolerant attitude toward people with mental disorders. Clergy with contact with people with mental disorders were more likely to perceive depression as treatable...
January 15, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29335236/tanzania-health-information-technology-t-hit-system-pilot-test-of-a-tablet-based-system-to-improve-prevention-of-mother-to-child-transmission-of-hiv
#10
Sheana Bull, Deborah Sk Thomas, Elias C Nyanza, Sospatro E Ngallaba
BACKGROUND: The prevention of mother-to-child transmission (PMTCT) of HIV requires innovative solutions. Although routine monitoring is effective in some areas, standardized and easy-to-scale solutions to identify and monitor pregnant women, test them for HIV, and treat them and their children is still lacking. Mobile health (mHealth) offers opportunities for surveillance and reporting in rural areas of low- and middle-income countries. OBJECTIVE: The aim of this study was to document the preliminary impacts of the Tanzania Health Information Technology (T-HIT) system mHealth intervention aimed at health workers for PMTCT care delivery and capacity building in a rural area of Tanzania...
January 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29332236/child-desire-among-men-and-women-living-with-hiv-aids-in-the-traditional-culture-of-vietnam
#11
Bach Xuan Tran, Ha Dai Duong, Anh Quynh Nguyen, Linh Dieu Pham, Tung Thanh Tran, Carl A Latkin
In various settings, heterogeneity in fertility rates among HIV-affected couples highlights the importance of understanding contextual factors to inform program planning and implementation. We interviewed 1016 patients with HIV/AIDS at seven clinics in Vietnam to assess their desire to have a(nother) child and willingness to pay (WTP) for prevention of mother to child transmission (PMTCT) services. One-fifth of participants reported their desire for a(another) child and this was slightly higher among men than women...
January 13, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29329386/the-role-of-service-readiness-and-health-care-facility-factors-in-attrition-from-option-b-in-haiti-a-joint-examination-of-electronic-medical-records-and-service-provision-assessment-survey-data
#12
Lauren Lipira, Christopher Kemp, Jean Wysler Domercant, Jean Guy Honoré, Kesner Francois, Nancy Puttkammer
Background: Option B+ is a strategy wherein pregnant or breastfeeding women with HIV are enrolled in lifelong antiretroviral therapy (ART) for prevention of mother-to-child transmission (PMTCT) of HIV. In Haiti, attrition from Option B+ is problematic and variable across health care facilities. This study explores service readiness and other facility factors as predictors of Option B+ attrition in Haiti. Methods: This analysis used longitudinal data from 2012 to 2014 from the iSanté electronic medical record system and cross-sectional data from Haiti's 2013 Service Provision Assessment...
January 10, 2018: International Health
https://www.readbyqxmd.com/read/29325561/workforce-patterns-in-the-prevention-of-mother-to-child-transmission-of-hiv-in-c%C3%A3-te-d-ivoire-a-qualitative-model
#13
Brianne H Rowan, Julia Robinson, Adam Granato, Claire Konan Bla, Seydou Kouyaté, Guy Vincent Djety, Kouamé Abo, Ahoua Koné, Stephen Gloyd
BACKGROUND: Côte d'Ivoire continues to struggle with one of the highest rates of mother-to-child HIV transmission in West Africa, previously thought to be in part due to suboptimal workforce patterns. This study aimed to understand the process through which workforce patterns impact prevention of mother-to child transmission of HIV (PMTCT) program success, from the perspective of healthcare workers in Côte d'Ivoire. METHODS: A total of 142 semi-structured interviews were conducted with physicians, midwives, nurses, community counselors, social workers, pharmacists, management personnel and health aides from a nationally representative sample of 48 PMTCT sites across Côte d'Ivoire...
January 11, 2018: Human Resources for Health
https://www.readbyqxmd.com/read/29321026/lay-health-worker-experiences-administering-a-multi-level-combination-intervention-to-improve-pmtct-retention
#14
Abby DiCarlo, Ruby Fayorsey, Masila Syengo, Duncan Chege, Martin Sirengo, William Reidy, Juliana Otieno, Jackton Omoto, Mark P Hawken, Elaine J Abrams
BACKGROUND: The recent scale-up of prevention of mother-to-child transmission of HIV (PMTCT) services has rapidly accelerated antiretroviral therapy (ART) uptake among pregnant and postpartum women in sub-Saharan Africa. The Mother and Infant Retention for Health (MIR4Health) study evaluates the impact of a combination intervention administered by trained lay health workers to decrease attrition among HIV-positive women initiating PMTCT services and their infants through 6 months postpartum...
January 10, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29315112/what-is-new-in-perinatal-hiv-prevention
#15
Mary G Fowler, Patricia Flynn, Jim Aizire
PURPOSE OF REVIEW: The purpose of this review is to describe recent clinical trial, laboratory and observational findings that highlight both the progress that can be achieved in elimination of new pediatric infections in international clinical trial settings among HIV-infected breastfeeding women while also describing recent safety concerns related to currently used antiretroviral regimens. The article will also address the ongoing adherence challenges for HIV-infected mothers in taking their antiretroviral drugs...
February 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29302320/knowledge-about-mother-to-child-transmission-of-hiv-its-prevention-and-associated-factors-among-ethiopian-women
#16
Tegene Regassa Luba, Zhanchun Feng, Simon Afewerki Gebremedhin, Asfaw N Erena, Abdulsalam Ma Nasser, Ghose Bishwajit, Shangfeng Tang
Background: Poor awareness and knowledge of mother-to-child transmission (MTCT),that accounts for over 90% of new HIV infections among children, might contribute to the HIV epidemics. In Ethiopia, 898 400 children are orphaned due to HIV and AIDS and 200 300 were living with HIV in 2013. The main objective of this study was to examine the knowledge of MTCT of HIV, its prevention (PMTCT) and associated factors among Ethiopian women. Methods: We conducted a cross-sectional analysis among 16 515 women from the Ethiopian Demographic Health Survey (EDHS) 2011...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29294576/-study-on-the-risk-of-mortality-and-associated-factors-among-hiv-exposed-children-in-henan-province-2002-2014
#17
Q Wang, N Ma, H Si, Y M Ma, N Li, Y G Nie, D Y Sun, Z Wang
Objective: To investigate the status of survival and related risk factors among HIV-exposed children in Henan province from 2002 to 2014. Methods: A follow-up program was set up when infants as 1, 3, 6, 9, 12, 18 month olds. Data regarding the HIV-exposed children and their mothers were collected, including service of PMTCT, antiviral therapy, incidence of infectious disease and survival status of infants. Univariate and multivariate logistic regression models were used to explore the risk factors. Results: A total number of 1 705 HIV-infected infants were reported from 2002 to 2014...
December 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29287029/retention-in-hiv-care-during-pregnancy-and-the-postpartum-period-in-the-option-b-era-a-systematic-review-and-meta-analysis-of-studies-in-africa
#18
Brandon A Knettel, Cody Cichowitz, James Samwel Ngocho, Elizabeth T Knippler, Lilian N Chumba, Blandina T Mmbaga, Melissa H Watt
BACKGROUND: Under Option B+ guidelines for prevention of mother-to-child transmission of HIV (PMTCT), pregnant and breastfeeding women initiate antiretroviral therapy (ART) for lifelong use. The objectives of this study were: 1) to synthesize data on retention in care over time in Option B+ programs in Africa, and 2) to identify factors associated with retention in care. METHODS: PubMed, EMBASE, and African Index Medicus were systematically searched from January 2012 to June 2017...
December 27, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29248014/a-cluster-randomized-controlled-trial-of-lay-health-worker-support-for-prevention-of-mother-to-child-transmission-of-hiv-pmtct-in-south-africa
#19
Karl Peltzer, Stephen M Weiss, Manasi Soni, Tae Kyoung Lee, Violeta J Rodriguez, Ryan Cook, Maria Luisa Alcaide, Geoffrey Setswe, Deborah L Jones
BACKGROUND: We evaluate the impact of clinic-based PMTCT community support by trained lay health workers in addition to standard clinical care on PMTCT infant outcomes. METHODS: In a cluster randomized controlled trial, twelve community health centers (CHCs) in Mpumalanga Province, South Africa, were randomized to have pregnant women living with HIV receive either: a standard care (SC) condition plus time-equivalent attention-control on disease prevention (SC; 6 CHCs; n  = 357), or an enhanced intervention (EI) condition of SC PMTCT plus the "Protect Your Family" intervention (EI; 6 CHCs; n  = 342)...
December 16, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/29236624/a-socio-ecological-examination-of-treatment-access-uptake-and-adherence-issues-encountered-by-hiv-positive-women-in-rural-north-central-nigeria
#20
Llewellyn J Cornelius, Salome C Erekaha, Joshua N Okundaye, Nadia A Sam-Agudu
BACKGROUND: In spite of the global decline in HIV infections, sub-Saharan Africa still accounts for a non-proportional majority of global new infections. While many studies have documented the importance of facilitating access to anti-retroviral therapy (ART) as a means of reducing infections, the relationship between interpersonal, community, healthcare facility, and policy-level factors and treatment adherence in Africa have not been well-described. The authors examined these factors in the context of prevention of mother-to-child transmission (PMTCT) of HIV in rural north-central Nigeria, where HIV burden is high and service coverage is low...
December 13, 2017: Journal of Evidence-informed Social Work
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