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https://www.readbyqxmd.com/read/28528032/a-surprising-alliance-two-giants-of-the-20th-century
#1
Robert M Sade
Alexis Carrel and Charles Lindbergh were among the most famous international figures in the 20th century: Carrel, the surgeon-scientist who won a Nobel prize as a young surgeon, and Lindbergh, the aviator-engineer who pioneered aviation and promoted commercial flight throughout his life. Surprisingly, these two amazing individuals came together to collaborate on the early development of extracorporeal circulation. Their work was interrupted by the onset of World War II, which destroyed one of them and nearly destroyed the other...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527985/long-term-follow-up-and-impact-of-comorbidity-prior-to-allogeneic-hematopoietic-stem-cell-transplantation-in-patients-with-relapsed-or-refractory-aml-lessons-learned-from-the-prospective-bridge-trial-clofarabine-salvage-therapy-prior-to-allogeneic-transplantation
#2
Jan Moritz Middeke, Regina Herbst, Stefani Parmentier, Gesine Bug, Mathias Hänel, Gernot Stuhler, Kerstin Schäfer-Eckart, Wolf Rösler, Stefan Klein, Wolfgang Bethge, Ulrich Bitz, Bozena Büttner, Holger Knoth, Nael Alakel, Markus Schaich, Anke Morgner, Michael Kramer, Katja Sockel, Malte von Bonin, Friedrich Stölzel, Uwe Platzbecker, Christoph Röllig, Christian Thiede, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig
In patients with relapsed or refractory (r/r) AML, allogeneic Hematopoietic Stem Cell Transplantation (HSCT) is considered to be the only treatment providing long-term disease control. The BRIDGE trial studied the safety and efficacy of a clofarabine-based salvage therapy prior to HSCT in patients with r/r AML. Here, we report the long-term follow up of this Phase II, multi-center trial and exploratory analyses on the impact of comorbidity on outcome. Eighty-four patients with a median age of 61 years (range 40 - 75) were enrolled...
May 17, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28527672/quality-of-life-among-long-term-survivors-of-advanced-stage-ovarian-cancer-a-cross-sectional-approach
#3
Susan K Lutgendorf, Eileen Shinn, Jeanne Carter, Susan Leighton, Keith Baggerly, Michele Guindani, Bryan Fellman, Marianne Matzo, George M Slavich, Marc T Goodman, William Tew, Jenny Lester, Kathleen M Moore, Beth Y Karlan, Douglas A Levine, Anil K Sood
PURPOSE: Long-term survival of women with advanced-stage ovarian cancer is relatively rare. Little is known about quality of life (QOL) and survivorship concerns of these women. Here, we describe QOL of women with advanced-stage ovarian cancer surviving for 8.5 years or longer and compare women with 0-1 recurrence to those with multiple recurrences. METHODS: Participants (n=56) recruited from 5 academic medical centers and the Ovarian Cancer Research Fund Alliance completed surveys regarding QOL (FACT-O), mood (CESD), social support (SPS), physical activity (IPAQ-SF), diet, and clinical characteristics...
May 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28524700/what-is-important-in-transdisciplinary-pain-neuroscience-education-a-qualitative-study
#4
Amarins J Wijma, Caroline M Speksnijder, Astrid F Crom-Ottens, J M Corine Knulst-Verlaan, Doeke Keizer, Jo Nijs, C Paul van Wilgen
PURPOSE: The main focus of Pain Neuroscience Education is around changing patients' pain perceptions and minimizing further medical care. Even though Pain Neuroscience Education has been studied extensively, the experiences of patients regarding the Pain Neuroscience Education process remain to be explored. Therefore, the aim of this study was to explore the experiences in patients with non-specific chronic pain. MATERIALS AND METHODS: Fifteen patients with non-specific chronic pain from a transdisciplinary treatment centre were in-depth interviewed...
May 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28523966/relationship-centered-dementia-care-insights-from-a-community-based-culture-change-coalition
#5
Lorna de Witt, Darla Fortune
This article reports on the work of a community-based culture change coalition affiliated with the Partnerships in Dementia Care Alliance, a research network committed to strengthening dementia care through supporting relationship-centered care approaches. Research to date emphasizes negative aspects of dementia care relationships. Drawing on data the culture change coalition collected as part of their culture change work using participatory action research guided by appreciative inquiry, this article examines what relationship qualities contributed to positive dementia care experiences and how positive relationships were created...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28521033/lymph-node-metastases-in-thymic-malignancies-a-chinese-alliance-for-research-in-thymomas-retrospective-database-analysis%C3%A2
#6
Zhitao Gu, Yucheng Wei, Jianhua Fu, Lijie Tan, Peng Zhang, Yongtao Han, Chun Chen, Renquan Zhang, Yin Li, Keneng Chen, Hezhong Chen, Yongyu Liu, Youbing Cui, Yun Wang, Liewen Pang, Zhentao Yu, Xinming Zhou, Yangchun Liu, Yi Shen, Wentao Fang
OBJECTIVES: Lymphatic involvement is believed to be relatively rare in thymic epithelial tumours. The incidence and prognostic significance of nodal metastases are still unclear. The goal of this study was to define the incidence and prognostic relevance of nodal metastasis in patients with thymic epithelial tumours, using a nationwide retrospective database of the Chinese Alliance for Research in Thymomas. METHODS: Patients who underwent upfront surgical resection without preoperative therapy were enrolled for the study...
May 18, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28517993/your-dna-your-say
#7
Anna Middleton
Genomic and medical data sharing is pivotal if the promise of genomic medicine is to be fully realised. Social scientists working in the genomics arena ask the public 'how is the technology working for you?' Empirical studies on attitudes, values and beliefs are incredibly valuable; they offer a voice from those who are, or will be, directly affected. This is paramount if personalised medicine is to be truly personal. An International attitude study, Your DNA, Your Say, uses film to provide background information and an online survey to gather public views on donating one's own personal DNA and medical data for use by others...
April 2017: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28517986/from-rosalind-franklin-to-barack-obama-data-sharing-challenges-and-solutions-in-genomics-and-personalised-medicine
#8
Mark Lawler, Tim Maughan
The collection, storage and use of genomic and clinical data from patients and healthy individuals is a key component of personalised medicine enterprises such as the Precision Medicine Initiative, the Cancer Moonshot and the 100,000 Genomes Project. In order to maximise the value of this data, it is important to embed a culture within the scientific, medical and patient communities that supports the appropriate sharing of genomic and clinical information. However, this aspiration raises a number of ethical, legal and regulatory challenges that need to be addressed...
April 2017: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28515548/culturally-relevant-family-therapy-practice-with-parents-of-children-and-adolescents
#9
Tania Roy, A Thirumoorthy, R Parthasarathy
BACKGROUND: India is diverse in culture, with multiple aspects that may not match with the Western societal picture. Hence, it has often been seen that therapists encounter unique aspects of therapy that is faced during actual practice, which is never written in any textbook or research papers. Substantial information is present through both outcome (efficacy and effectiveness) studies and process research, but it has very little impact of actual Marital and Family Therapy (MFT) practice...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28514865/therapeutic-alliance-in-youth-with-autism-spectrum-disorder-receiving-cognitive-behavioral-treatment-for-anxiety
#10
Connor M Kerns, Amanda Collier, Adam B Lewin, Eric A Storch
Symptoms of autism spectrum disorder may influence alliance in psychotherapy. This study examined therapeutic alliance and its relationship with child characteristics and anxiety treatment outcomes in youth with autism spectrum disorder. Youth ( N = 64) with autism spectrum disorder and co-occurring anxiety (7-16 years, IQ > 70) received 16 sessions of modular cognitive-behavioral therapy. Post-treatment therapist, youth and parent ratings of alliance as well as pre- and post-treatment ratings of child behavior were gathered...
May 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28514670/radiation-safety-in-children-with-congenital-and-acquired-heart-disease-a-scientific-position-statement-on-multimodality-dose-optimization-from-the-image-gently-alliance
#11
REVIEW
Kevin D Hill, Donald P Frush, B Kelly Han, Brian G Abbott, Aimee K Armstrong, Robert A DeKemp, Andrew C Glatz, S Bruce Greenberg, Alexander Sheldon Herbert, Henri Justino, Douglas Mah, Mahadevappa Mahesh, Cynthia K Rigsby, Timothy C Slesnick, Keith J Strauss, Sigal Trattner, Mohan N Viswanathan, Andrew J Einstein
There is a need for consensus recommendations for ionizing radiation dose optimization during multi-modality medical imaging in children with congenital and acquired heart disease (CAHD). These children often have complex diseases and may be exposed to a relatively high cumulative burden of ionizing radiation from medical imaging procedures including cardiac computed tomography, nuclear cardiology studies and fluoroscopically guided diagnostic and interventional catheterization and electrophysiology procedures...
May 17, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28511729/juicy-conceptualizations-increasing-alliance-through-attending-to-client-metaphoric-language
#12
Fiona Mathieson, Jennifer Jordan, Paul Merrick, Maria Stubbe
BACKGROUND: There is increasing interest in the use of metaphor in cognitive behaviour therapy. Experts advocate bringing client metaphors into case conceptualizations, but there is little empirical research to support this. AIMS: This study evaluated the effect of training 12 therapists to attend to client metaphors and bring them into case conceptualizations. METHOD: Pre- and post-training role-played therapy sessions were conducted and video-recorded...
May 17, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28511238/-subjective-adverse-effects-during-outpatient-cbt-associations-to-patient-and-therapist-variables-and-to-the-therapeutic-alliance
#13
Anne Grüneberger, Franziska Einsle, Jürgen Hoyer, Bernhard Strauß, Michael Linden, Samia Härtling
Background Empirical data on variety, frequency, and prerequisites for unwanted side effects of psychotherapies are important regarding the planning, realization, and quality assurance of treatment. The study describes adverse effects of outpatient psychotherapy treatment and their association with patient, therapist and treatment characteristics. Methods To reduce memory bias, 70 outpatient psychotherapy patients fulfilled the Inventory for the Assessment of Negative Effects of Psychotherapy (INEP). Data on patients' characteristics (sex, age, impairment), therapists' sex, and therpeutic alliance were collected...
May 16, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28510191/taxonomy-of-cyrtochilum-alliance-orchidaceae-in-the-light-of-molecular-and-morphological-data
#14
Dariusz L Szlachetko, Marta Kolanowska, Aleksandra Naczk, Marcin Górniak, Magdalena Dudek, Piotr Rutkowski, Guy Chiron
BACKGROUND: The generic separateness and specific composition of the orchid genus Cyrtochilum was discussed for almost two centuries. Over the years several smaller taxa were segregated from this taxon, but their separateness was recently questioned based on molecular studies outcomes. The aim of our study was to revise concepts of morphological-based generic delimitation in Cyrtochilum-alliance and to compare it with the results of genetic analysis. We used phylogenetic framework in combination with phenetical analysis to provide proposal of the generic delimitation within Cyrtochilum-alliance...
December 2017: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28509624/the-role-of-evidence-based-therapy-relationships-on-treatment-outcome-for-adults-with-trauma-a-systematic-review
#15
Amy E Ellis, Vanessa Simiola, Laura Brown, Christine Courtois, Joan M Cook
OBJECTIVE: The purpose of this paper was to systematically review and synthesize the empirical literature on the effects of evidence-based therapy relationship (EBR) variables in the psychological treatment for adults who experienced trauma-related distress. METHOD: Studies were identified using comprehensive searches of PsycINFO, Medline, Published International Literature on Traumatic Stress, and Cumulative Index to Nursing and Allied Health Literature databases...
May 16, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28508237/development-of-a-unifying-target-and-consensus-indicators-for-global-surgical-systems-strengthening-proposed-by-the-global-alliance-for-surgery-obstetric-trauma-and-anaesthesia-care-the-g4-alliance
#16
REVIEW
Adil Haider, John W Scott, Colin D Gause, Mira Meheš, Grace Hsiung, Albulena Prelvukaj, Dana Yanocha, Lauren M Baumann, Faheem Ahmed, Na'eem Ahmed, Sara Anderson, Herve Angate, Lisa Arfaa, Horacio Asbun, Tigistu Ashengo, Kisembo Asuman, Ruben Ayala, Stephen Bickler, Saul Billingsley, Peter Bird, Matthijs Botman, Marilyn Butler, Jo Buyske, Angelo Capozzi, Kathleen Casey, Charles Clayton, James Cobey, Michael Cotton, Dan Decklebaum, Milliard Derbew, Catherine deVries, Jeanne Dillner, Max Downham, Natalie Draisin, David Echinard, Sohier Elneil, Ahmed ElSayed, Abigail Estelle, Allen Finley, Erica Frenkel, Philip K Frykman, Florin Gheorghe, Julian Gore-Booth, Richard Henker, Jaymie Henry, Orion Henry, Laura Hoemeke, David Hoffman, Iko Ibanga, Eric V Jackson, Pankaj Jani, Walter Johnson, Andrew Jones, Zeina Kassem, Asuman Kisembo, Abbey Kocan, Sanjay Krishnaswami, Robert Lane, Asad Latif, Barbara Levy, Dimitrios Linos, Peter Linz, Louis A Listwa, Declan Magee, Emmanuel Makasa, Michael L Marin, Claude Martin, Kelly McQueen, Jaime Morgan, Richard Moser, Robert Neighbor, William M Novick, Stephen Ogendo, Akinyinka Omigbodun, Bisola Onajin-Obembe, Neil Parsan, Beverly K Philip, Raymond Price, Shahnawaz Rasheed, Marjorie Ratel, Cheri Reynolds, Steven M Roser, Jackie Rowles, Lubna Samad, John Sampson, Harshadkumar Sanghvi, Marchelle L Sellers, David Sigalet, Bruce C Steffes, Erin Stieber, Mamta Swaroop, John Tarpley, Asha Varghese, Julie Varughese, Richard Wagner, Benjamin Warf, Neil Wetzig, Susan Williamson, Joshua Wood, Anne Zeidan, Lewis Zirkle, Brendan Allen, Fizan Abdullah
After decades on the margins of primary health care, surgical and anaesthesia care is gaining increasing priority within the global development arena. The 2015 publications of the Disease Control Priorities third edition on Essential Surgery and the Lancet Commission on Global Surgery created a compelling evidenced-based argument for the fundamental role of surgery and anaesthesia within cost-effective health systems strengthening global strategy. The launch of the Global Alliance for Surgical, Obstetric, Trauma, and Anaesthesia Care in 2015 has further coordinated efforts to build priority for surgical care and anaesthesia...
May 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28506378/pharmacist-to-prescriber-intervention-to-close-therapeutic-gaps-for-statin-use-in-patients-with-diabetes-a-randomized-controlled-trial
#17
Hannah M Renner, Amanda Hollar, Samuel F Stolpe, Macary Weck Marciniak
OBJECTIVE: To assess the effect of a community pharmacist-led intervention on the proportion of patients with diabetes placed on statin therapy. DESIGN: The Pharmacy Quality Alliance endorsed a performance measure, Statin Use in Persons with Diabetes, which evaluates the percentage of patients aged 40-75 years who were dispensed a medication for diabetes and also received a statin medication. SETTING: This new measure has been implemented within the Electronic Quality Improvement Platform for Plans and Pharmacies (EQuIPP) dashboard...
May 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28506219/sexual-orientation-differences-in-treatment-expectation-alliance-and-outcome-among-patients-at-risk-for-suicide-in-a-public-psychiatric-hospital
#18
Martin Plöderl, Sabine Kunrath, Robert J Cramer, Jen Wang, Larissa Hauer, Clemens Fartacek
BACKGROUND: Sexual minority (SM) individuals (gay, lesbian, bisexual, or otherwise nonheterosexual) are at increased risk for mental disorders and suicide and adequate mental healthcare may be life-saving. However, SM patients experience barriers in mental healthcare that have been attributed to the lack of SM-specific competencies and heterosexist attitudes and behaviors on the part of mental health professionals. Such barriers could have a negative impact on common treatment factors such as treatment expectancy or therapeutic alliance, culminating in poorer treatment outcomes for SM versus heterosexual patients...
May 15, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28505058/organizational-regional-and-community-factors-determining-protocol-compliance-for-patients-with-acute-myocardial-infarction
#19
Teresa W Tai, Sherry I Bame, Nitish Patidar
This study examined factors determining hospital compliance to Hospital Quality Alliance's protocol for patients with myocardial infarction. Using a spatially matched sample of 132 Magnet and 264 non-Magnet hospitals, multivariate regressions determined significant hospital characteristics associated with compliance per Hospital Quality Alliance protocol. Adherence to the Hospital Quality Alliance protocols varied widely by hospital characteristics. Registered nurse staffing/bed was a key factor determining patient care quality variation...
May 12, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28504541/interpersonal-pathoplasticity-and-trajectories-of-change-in-routine-adolescent-and-young-adult-residential-substance-abuse-treatment
#20
James F Boswell, Nicole M Cain, Jennifer M Oswald, Andrew A McAleavey, Robert Adelman
BACKGROUND: Partnerships between mental health care stakeholders provide a context for generalizable clinical research with implications for quality improvement. In the context of a partnership between an adolescent residential substance abuse disorder (SUD) treatment center and clinical researchers, stakeholders identified knowledge gaps (internal and the field broadly) with regard to patient interpersonal factors that influence working alliance and acute SUD residential treatment outcome trajectories...
May 15, 2017: Journal of Consulting and Clinical Psychology
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