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https://www.readbyqxmd.com/read/29036317/quality-of-local-school-wellness-policies-for-physical-activity-and-resultant-implementation-in-pennsylvania-schools
#1
E Francis, E Hivner, A Hoke, T Ricci, A Watach, J Kraschnewski
Background: In 2006, United States public schools participating in federal school meal programs were required to adopt school wellness policies. The effect of these policies on school nutrition environments is well documented; however, evaluation of physical activity policies has received less investigation. We aimed to evaluate how district wellness policies aligned to practice for physical activity implementation in 40 schools with high obesity rates (>24%). Methods: Wellness policies were evaluated using the validated Wellness School Assessment Tool (WellSAT)...
September 28, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29035800/exploring-mechanisms-of-change-in-schema-therapy-for-chronic-depression
#2
Fritz Renner, Robert DeRubeis, Arnoud Arntz, Frenk Peeters, Jill Lobbestael, Marcus J H Huibers
BACKGROUND AND OBJECTIVES: The underlying mechanisms of symptom change in schema therapy (ST) for chronic major depressive disorder (cMDD) have not been studied. The aim of this study was to explore the impact of two potentially important mechanisms of symptom change, maladaptive schemas (proxied by negative idiosyncratic core-beliefs) and the therapeutic alliance. METHODS: We drew data from a single-case series of ST for cMDD. Patients with cMDD (N = 20) received on average 78 repeated weekly assessments over a course of up to 65 individual sessions of ST...
October 6, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29034755/the-alliance-with-expanding-blood-volume-and-correcting-anemia-is-an-effective-therapeutic-measure-for-the-adult-anemia-patients-of-acute-cerebral-infarction
#3
Zunyu Ke, Yu Zhao, Chuanling Wang, Zhiyou Cai
Anemia is closely associated with the occurrence and development of ischemic stroke. However, the clinical association between anemia and ischemic stroke remains unclear. We evaluated the clinical features of adult patients of acute cerebral infarction with anemia, and to provide a reference in the treatment of the anemia patients of acute cerebral infarction, and seek a better treatment different from the other non-anemia causes. We found that anemia has rendered valuable service to neuronal damage and subsequent deterioration of acute cerebral infarction in the adults...
October 15, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29034366/a-phase-2-study-incorporating-sorafenib-into-the-chemotherapy-for-older-adults-with-flt3-mutated-acute-myeloid-leukemia-calgb-11001
#4
Geoffrey L Uy, Sumithra J Mandrekar, Kristina Laumann, Guido Marcucci, Weiqiang Zhao, Mark J Levis, Heidi D Klepin, Maria R Baer, Bayard L Powell, Peter Westervelt, Daniel J DeAngelo, Wendy Stock, Ben Sanford, William G Blum, Clara D Bloomfield, Richard M Stone, Richard A Larson
The Cancer and Leukemia Group B (CALGB), now part of the Alliance for Clinical Trials in Oncology, conducted a multicenter, single-arm, phase 2 study in patients ≥60 years with FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia (AML). In this study, sorafenib was added to daunorubicin and cytarabine-based induction and consolidation chemotherapy and was also continued for 12 months of maintenance therapy. The primary end point of the study was overall survival (OS) at 1 year in the FLT3 internal tandem duplication (FLT3-ITD) cohort...
January 24, 2017: Blood Advances
https://www.readbyqxmd.com/read/29034240/dark-chocolate-opportunity-for-an-alliance-between-medical-science-and-the-food-industry
#5
Ivan M Petyaev, Yuriy K Bashmakov
Dark chocolate (DC) was originally introduced in human nutrition as a medicinal product consumable in a liquid form. Century-long efforts of food industry transformed this hardly appealing product into a valuable modern culinary delight with clear predominance of confectionery brands of DC on the market. However, current epidemiological data as well as multiple experimental and clinical observations reveal that DC consumption may have a profound effect on cardiovascular, central nervous systems, hemostasis, and lipid metabolism...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29032496/school-practices-to-foster-lgbt-supportive-climate-associations-with-adolescent-bullying-involvement
#6
Amy L Gower, Myriam Forster, Kari Gloppen, Abigail Z Johnson, Marla E Eisenberg, John E Connett, Iris W Borowsky
Lesbian, gay, bisexual, and transgender (LGBT) youth experience disproportionate rates of bullying compared to their heterosexual peers. Schools are well-positioned to address these disparities by creating supportive school climates for LGBT youth, but more research is needed to examine the variety of practices and professional development opportunities put in place to this end. The current study examines how school practices to create supportive LGBT student climate relate to student reports of bullying. Student-level data come from the 2013 Minnesota Student Survey, a state-wide survey of risk and protective factors...
October 14, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29032356/cell-scientist-to-watch-mahak-sharma
#7
(no author information available yet)
Mahak Sharma graduated with a bachelor's degree in biotechnology from the Guru Gobind Singh Indraprastha University, Delhi, India. She then moved to the laboratory of Steve Caplan at the University of Nebraska Medical Center, Omaha, USA, where she received her PhD in 2009. After post-doctoral research with Michael Brenner at the Department of Rheumatology, Immunology and Allergy at Harvard Medical School, she returned to India in 2011 as an Assistant Professor at the Indian Institute of Science, Education and Research (IISER) in Mohali...
October 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29030503/a-qualitative-study-of-a-blended-therapy-using-problem-solving-therapy-with-a-customised-smartphone-app-in-men-who-present-to-hospital-with-intentional-self-harm
#8
Craig Mackie, Nicole Dunn, Sarah MacLean, Valerie Testa, Marnin Heisel, Simon Hatcher
BACKGROUND: Blended therapy describes the use of computerised therapy combined with face-to-face therapy to extend the depth, range and nature of the face-to-face therapy. We wanted to develop a treatment manual for a randomised trial of blended therapy combining face-to-face problem solving and a smartphone app in men who present to hospital with self-harm. OBJECTIVE: To develop a treatment manual and to describe the experience of receiving and delivering a blended therapy...
October 13, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29030285/clinical-applications-of-3d-printing-primer-for-radiologists
#9
REVIEW
David H Ballard, Anthony Paul Trace, Sayed Ali, Taryn Hodgdon, Matthew E Zygmont, Carolynn M DeBenedectis, Stacy E Smith, Michael L Richardson, Midhir J Patel, Summer J Decker, Leon Lenchik
Three-dimensional (3D) printing refers to a number of manufacturing technologies that create physical models from digital information. Radiology is poised to advance the application of 3D printing in health care because our specialty has an established history of acquiring and managing the digital information needed to create such models. The 3D Printing Task Force of the Radiology Research Alliance presents a review of the clinical applications of this burgeoning technology, with a focus on the opportunities for radiology...
October 10, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29030284/structured-reporting-in-radiology
#10
REVIEW
Dhakshinamoorthy Ganeshan, Phuong-Anh Thi Duong, Linda Probyn, Leon Lenchik, Tatum A McArthur, Michele Retrouvey, Emily H Ghobadi, Stephane L Desouches, David Pastel, Isaac R Francis
Radiology reports are vital for patient care as referring physicians depend upon them for deciding appropriate patient management. Traditional narrative reports are associated with excessive variability in the language, length, and style, which can minimize report clarity and make it difficult for referring clinicians to identify key information needed for patient care. Structured reporting has been advocated as a potential solution for improving the quality of radiology reports. The Association of University Radiologists-Radiology Research Alliance Structured Reporting Task Force convened to explore the current and future role of structured reporting in radiology and summarized its finding in this article...
October 10, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29030283/logistics-of-three-dimensional-printing-primer-for-radiologists
#11
REVIEW
Taryn Hodgdon, Raman Danrad, Midhir J Patel, Stacy E Smith, Michael L Richardson, David H Ballard, Sayed Ali, Anthony Paul Trace, Carolynn M DeBenedectis, Matthew E Zygmont, Leon Lenchik, Summer J Decker
The Association of University Radiologists Radiology Research Alliance Task Force on three-dimensional (3D) printing presents a review of the logistic considerations for establishing a clinical service using this new technology, specifically focused on implications for radiology. Specific topics include printer selection for 3D printing, software selection, creating a 3D model for printing, providing a 3D printing service, research directions, and opportunities for radiologists to be involved in 3D printing...
October 10, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29026204/engineering-and-physical-sciences-in-oncology-challenges-and-opportunities
#12
REVIEW
Michael J Mitchell, Rakesh K Jain, Robert Langer
The principles of engineering and physics have been applied to oncology for nearly 50 years. Engineers and physical scientists have made contributions to all aspects of cancer biology, from quantitative understanding of tumour growth and progression to improved detection and treatment of cancer. Many early efforts focused on experimental and computational modelling of drug distribution, cell cycle kinetics and tumour growth dynamics. In the past decade, we have witnessed exponential growth at the interface of engineering, physics and oncology that has been fuelled by advances in fields including materials science, microfabrication, nanomedicine, microfluidics, imaging, and catalysed by new programmes at the National Institutes of Health (NIH), including the National Institute of Biomedical Imaging and Bioengineering (NIBIB), Physical Sciences in Oncology, and the National Cancer Institute (NCI) Alliance for Nanotechnology...
October 13, 2017: Nature Reviews. Cancer
https://www.readbyqxmd.com/read/29023215/cost-effectiveness-analysis-of-monthly-zoledronic-acid-zoledronic-acid-every-3-months-and-monthly-denosumab-in-women-with-breast-cancer-and-skeletal-metastases-calgb-70604-alliance
#13
Charles L Shapiro, James P Moriarty, Stacie Dusetzina, Andrew L Himelstein, Jared C Foster, Stephen S Grubbs, Paul J Novotny, Bijan J Borah
Purpose Skeletal-related events (SREs) such as pathologic fracture, spinal cord compression, or the necessity for radiation or surgery to bone metastasis cause considerable morbidity, decrements in quality of life, and costs to the health care system. The results of a recent large randomized trial (Cancer and Leukemia Group B/Alliance for Clinical Trials in Oncology [CALGB/Alliance 70604]) showed that zoledronic acid (ZA) every 3 months was noninferior to monthly ZA in reducing the risks of SREs. We sought to determine the cost-effectiveness (CE) of monthly ZA, ZA every 3 months, and monthly denosumab in women with breast cancer and skeletal metastases...
October 12, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29021105/invasive-pneumococcal-pneumonia-caused-by-13-valent-pneumococcal-conjugate-vaccine-types-in-children-with-different-schedules
#14
Hong-Yi Lee, Yu-Chia Hsieh, Ching-Chuan Liu, Yi-Chuan Huang, Kuang-Yi Chang, Hsin Chi, Luan-Yin Chang, Yhu-Chering Huang, Li-Min Huang
BACKGROUND: In Taiwan, the age group with the greatest incidence of invasive pneumococcal disease is 2-5 years of age, which is different from other countries. This study was conducted to identify risk factors and different 13-valent pneumococcal conjugate vaccine (PCV13) schedules associated with vaccine-type invasive pneumococcal pneumonia (IPP) despite prior vaccination. METHODS: A case-control study was conducted prospectively between August 2012 and December 2015 at five participating medical centers...
September 27, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29018565/health-related-quality-of-life-and-depression-among-participants-in-the-sj%C3%A3-gren-s-international-collaborative-clinical-alliance-registry
#15
Annie Chou, John A Gonzales, Troy E Daniels, Lindsey A Criswell, Stephen C Shiboski, Caroline H Shiboski
OBJECTIVE: To examine health-related quality of life (HRQoL) and depression among participants in an international Sjögren's syndrome (SS) registry, comparing those with and without SS. METHODS: Cross-sectional study of participants in the Sjögren's International Collaborative Clinical Alliance (SICCA) registry. The 2016 American College of Rheumatology/European League Against Rheumatism SS classification criteria were used to determine disease status. HRQoL was assessed using the Short Form 12, version 2 Health Survey to derive scores for physical component summary (PCS) and mental component summary (MCS)...
2017: RMD Open
https://www.readbyqxmd.com/read/29016887/phase-i-ii-trial-of-vorinostat-combined-with-temozolomide-and-radiation-therapy-for-newly-diagnosed-glioblastoma-final-results-of-alliance-n0874-abtc-02
#16
Evanthia Galanis, S Keith Anderson, C Ryan Miller, Jann N Sarkaria, Kurt Jaeckle, Jan C Buckner, Keith L Ligon, Karla V Ballman, Dennis F Moore, Michael Nebozhyn, Andrey Loboda, David Schiff, Manmeet Singh Ahluwalia, Eudocia Q Lee, Elizabeth R Gerstner, Glenn J Lesser, Michael Prados, Stuart A Grossman, Jane Cerhan, Caterina Giannini, Patrick Y Wen
Background: Vorinostat, a histone deacetylase inhibitor, has shown radiosensitizing properties in preclinical studies. This open-label, single-arm trial evaluated the maximum tolerated dose (MTD; phase I) and efficacy (phase II) of vorinostat combined with standard chemoradiation in newly diagnosed glioblastoma. Methods: Patients received oral vorinostat (300 or 400 mg/day) on days 1-5 weekly during temozolomide chemoradiation. Following a 4- to 6-week rest, patients received up to 12 cycles of standard adjuvant temozolomide and vorinostat (400 mg/day) on days 1-7 and 15-21 of each 28-day cycle...
August 22, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/29016596/experiences-of-operational-costs-of-hpv-vaccine-delivery-strategies-in-gavi-supported-demonstration-projects
#17
Siobhan Botwright, Taylor Holroyd, Shreya Nanda, Paul Bloem, Ulla K Griffiths, Anissa Sidibe, Raymond C W Hutubessy
From 2012 to 2016, Gavi, the Vaccine Alliance, provided support for countries to conduct small-scale demonstration projects for the introduction of the human papillomavirus vaccine, with the aim of determining which human papillomavirus vaccine delivery strategies might be effective and sustainable upon national scale-up. This study reports on the operational costs and cost determinants of different vaccination delivery strategies within these projects across twelve countries using a standardized micro-costing tool...
2017: PloS One
https://www.readbyqxmd.com/read/29016295/ignoring-the-itch-the-global-health-problem-of-scabies
#18
Lola V Stamm, Lindsay C Strowd
Infestation with Sarcoptes scabiei var. hominis is a common human parasitic affliction endemic in tropical developing countries. Scabies is transmitted by close person-person contact, and outbreaks have been reported in reception centers for asylum seekers. Scabies presents clinically as extremely pruritic excoriated papules and linear burrows in the skin. This infestation predisposes to bacterial skin infections that can result in serious complications affecting the kidneys and possibly the heart. Treatment of individuals with scabies and their close contacts involves the use of antiparasitic agents...
October 2, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28992959/a-national-survey-of-characteristics-of-child-advocacy-centers-in-the-united-states-do-the-flagship-models-match-those-in-broader-practice
#19
James Leslie Herbert, Wendy Walsh, Leah Bromfield
Child Advocacy Centers (CAC) emphasize developing effective cross-agency collaborations between workers involved in serious abuse investigations to foster improvements in agency outcomes, and to minimize distress, confusion and uncertainty for children and families. This study examined the characteristics of CACs, whether models in practice match the predominant model presented in the research literature. Directors of CACs in the United States that were members of the National Children's Alliance (NCA) mailing list (n=361) completed an online survey in 2016...
October 6, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28992823/impact-of-music-therapy-on-dementia-behaviors-a-literature-review
#20
Nora Fakhoury, Nathaniel Wilhelm, Kristen F Sobota, Kelly R Kroustos
Worldwide, dementia is the most important contributor to disability in elderly patients. Treating patients with dementia can be challenging for clinicians because of the numerous behavioral and psychological symptoms of dementia (BPSD). The Dementia Action Alliance and American Geriatrics Society Beers criteria promote nonpharmacological and behavioral treatments as first-line therapy to manage BPSD to avoid adverse events associated with antipsychotic medications. Some of the nonpharmacologic therapies proposed for BPSD include: music therapy (MT), light therapy, acupressure, aromatherapy, massage, and animal-assisted therapy...
October 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
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