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Contact dermatitis

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https://www.readbyqxmd.com/read/29916585/-occupational-allergic-contact-dermatitis-the-role-of-occupational-physician-in-the-prevention
#1
Francesca Larese Filon, Francesca Rui
OBJECTIVES: Occupational contact dermatitis are the second occupational diseases in industrialized countries and the preventive action and/or early diagnosis done by occupational physician (OP) is of paramount importance. METHODS: OP in the process of risk evaluation must suggest products, detergents and personal protective equipment with low irritant or sensitization potential. During work, the use of skin creams has to be promoted to prevent irritation that is the first step towards impairment of the skin barrier and sensitization...
November 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29911525/footwear-contact-dermatitis-a-prospective-cross-sectional-study-of-108-outpatients-from-delhi-india
#2
Farhan Rasool, Virendra N Sehgal, Govind Srivastava, Ashok Aggarwal, Iffat Hassan
Footwear contact dermatitis is a common problem with multifactorial exogenous, as well as endogenous, etiologies. Patch testing is the gold standard for detection of the possible contactants. A cross-sectional study was conducted in 108 outpatients over a period of 18 months. Demographic data comprising age, sex, and occupation were collected. Details of clinical and laboratory investigations were used to define the incriminating ingredient(s), subsequently confirmed by patch test using Indian standard and footwear series approved by the Contact and Occupational Dermatitis Forum of India...
2018: Skinmed
https://www.readbyqxmd.com/read/29908818/dermatoses-caused-by-cultural-practices-therapeutic-cultural-practices
#3
REVIEW
Neelam A Vashi, Nicole Patzelt, Stephen Wirya, Mayra B C Maymone, Pedro Zancanaro, Roopal V Kundu
With globalization and widespread immigration, physicians increasingly encounter patients from varying backgrounds and diverse customs. Although certain cultural practices are widely performed, there is limited medical literature describing their dermatologic and systemic effects and complications. Population diversity and sharing of traditions make it increasingly important for dermatologists to understand the role of cultural practices and recognize physiologic and pathologic sequelae. In addition, dermatologists are often adjured to assess skin findings that may be mistaken for abuse...
July 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29905921/pediatric-inpatient-and-emergency-dermatology-consultations-a-5-year-retrospective-analysis
#4
Mariana Cruz-Manzano, Cristina N Brau-Javier, Sheila Valentín-Nogueras, Luz D Figueroa-Guzmán
OBJECTIVE: To characterize and analyze the inpatient and emergency pediatric dermatology consults in our academic hospital center. METHODS: We reviewed 485 consultations that were done by the University of Puerto Rico Department of Dermatology from July 2007 to June 2012. The date, patient age and gender, consulting service, presumptive diagnosis, final diagnosis, and diagnostic procedures performed were documented for each consult. RESULTS: The patients' ages ranged from newborn to 18 years; the 13 to 18 years age group was the most common (29%)...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29903654/anti-pruritic-and-anti-inflammatory-effects-of-oxymatrine-in-a-mouse-model-of-allergic-contact-dermatitis
#5
Xiaoyun Xu, Wei Xiao, Zhe Zhang, Jianhao Pan, Yixi Yan, Tao Zhu, Dan Tang, Kaihe Ye, Manish Paranjpe, Lintao Qu, Hong Nie
BACKGROUND: Allergic contact dermatitis (ACD) is a highly prevalent inflammatory disease of the skin. As a result of the complex etiology in ACD, therapeutic compounds targeting refractory pruritus in ACD lack efficacy and lead to numerous side effects. OBJECTIVE: In this study, we investigated the anti-pruritic effects of oxymatrine (OMT) and explored its mechanism of action in a mouse model of ACD. METHOD: 72 male SPF C57BL/6 mice were randomly divided into control group, ACD model group, dexamethasone positive control group (0...
May 31, 2018: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29901500/glove-related-allergic-contact-dermatitis
#6
Anna E Kersh, Stephen Helms, Salma de la Feld
Hand dermatitis is a common condition with a lifetime prevalence of 20%. Glove allergic contact dermatitis (ACD) is a very important dermatitis affecting health care workers, hairdressers, cleaning personnel, kitchen workers, craftsmen, construction workers, laboratory workers, and homemakers. Occupationally related cases may be severe and can result in significant disability. Glove ACD is most commonly due to exposure to rubber accelerators, which are compounds that are added to rubber during production to increase strength and durability...
January 2018: Dermatitis
https://www.readbyqxmd.com/read/29897143/analysis-of-possible-structures-of-inducible-skin-associated-lymphoid-tissue-in-lupus-erythematosus-profundus
#7
Toshiaki Kogame, Ryosuke Yamashita, Masahiro Hirata, Tatsuki R Kataoka, Hisashi Kamido, Chiyuki Ueshima, Miho Matsui, Takashi Nomura, Kenji Kabashima
Lupus erythematosus profundus (LEP) is a variant of lupus erythematosus, involving the deep dermis and subcutaneous fat. LEP is characterized by the presence of lymphoid follicles (LF) and germinal centers (GC). However, it remains unknown whether these lymphoid structures correspond to the lymphoid tissues such as cutaneous tertiary lymphoid organs (TLO). Previously, we identified dynamically orchestrated cellular elements in murine contact dermatitis that resembled lymphoid structures, which we termed inducible skin-associated lymphoid tissues (iSALT)...
June 13, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29894934/aggregate-consumer-exposure-to-isothiazolinones-via-household-care-and-personal-care-products-probabilistic-modelling-and-benzisothiazolinone-risk-assessment
#8
Elena Garcia-Hidalgo, Dovilé Schneider, Natalie von Goetz, Christiaan Delmaar, Michael Siegrist, Konrad Hungerbühler
Consumers regularly use household care and personal care products (HC&PCPs). Isothiazolinones are included in HC&PCPs as preservatives and are being held responsible for an epidemic rise in allergic contact dermatitis (ACD). The objective of this study was to assess the origin and extent of dermal exposure in order to evaluate the risk of ACD from isothiazolinones in HC&PCP. Individual-based aggregate dermal exposure to four isothiazolinones was estimated using the newly proposed Probabilistic Aggregated Consumer Exposure Model-Kinetic, Dermal (PACEM-KD) by combining the reported individual use patterns for HC&PCP in Switzerland (N = 669 (558 adults), ages 0-91) with isothiazolinone concentrations measured in products used by the individual person...
June 9, 2018: Environment International
https://www.readbyqxmd.com/read/29894409/effectiveness-of-interventions-for-preventing-occupational-irritant-hand-dermatitis-a-quantitative-systematic-review
#9
Zoi Papadatou, Hector Williams, Kay Cooper
OBJECTIVE: The aim of this review was to identify, appraise and synthesize the best available evidence on the effectiveness of moisturizers, barrier creams, protective gloves, skin protection education and complex interventions (a combination of two or more of the interventions listed here) in preventing occupational irritant hand dermatitis (OIHD) in wet workers, comparing each intervention to an alternative intervention or to usual care (workers' regular skin care regimen). INTRODUCTION: The most significant occupational skin problem potentially encountered in wet work occupations is occupational dermatitis...
June 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29894020/the-role-of-skin-barrier-in-occupational-contact-dermatitis
#10
REVIEW
Ivone Jakasa, Jacob P Thyssen, Sanja Kezic
Skin diseases represent one of the most common work-related diseases and may have a detrimental effect on social, personal and occupational aspects of life. Contact dermatitis, which comprises predominately irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD) accounts for vast majority of occupational skin diseases, especially in occupations associated with frequent skin contact with irritants and contact allergens. Although ICD and ACD have similar clinical manifestation, their pathophysiology and the role of the skin barrier is different...
June 12, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29894005/possible-roles-of-basophils-in-chronic-itch
#11
REVIEW
Takashi Hashimoto, Jordan D Rosen, Kristen M Sanders, Gil Yosipovitch
Basophils are blood granulocytes and normally constitute less than 1% of blood peripheral leukocytes. Basophils share some morphological and functional similarities with mast cells, and basophils were once regarded as redundant and negligible circulating mast cells. However, recent studies reveal the indispensable roles of basophils in various diseases, including allergic and pruritic diseases. Basophils may be involved in itch through the mediation of a Th2 immune response, interaction with other cells in the skin, and secretion of a wide variety of itch-related mediators, e...
June 12, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29888412/allergic-contact-dermatitis-caused-by-acrylic-based-medical-dressings-and-adhesives
#12
Lien Mestach, Sara Huygens, An Goossens, Liesbeth Gilissen
BACKGROUND: Acrylates and methacrylates are acrylic resin monomers that are known to induce skin sensitization as a result of their presence in different materials, such as nail cosmetics, dental materials, printing inks, and adhesives. Allergic contact dermatitis resulting from the use of modern wound dressings containing them has only rarely been reported. OBJECTIVES: To describe 2 patients who developed allergic contact dermatitis caused by acrylic-based modern medical dressings and/or adhesives...
June 11, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29886752/tandem-repeated-irritation-test-trit-studies-and-clinical-relevance-post-2006
#13
Rasika Reddy, Howard Maibach
BACKGROUND/AIMS: Single or multiple applications of irritants can lead to occupational contact dermatitis, and most commonly irritant contact dermatitis (ICD). Tandem irritation, the sequential application of two irritants to a target skin area, has been studied using the Tandem Repeated Irritation Test (TRIT) to provide a more accurate representation of skin irritation. OBJECTIVE: Here we present an update to Kartono's review on tandem irritation studies since 2006 [1]...
June 11, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29882592/is-a-specific-eyelid-patch-test-series-useful-results-of-a-french-prospective-study
#14
Haudrey Assier, Florence Tetart, Martine Avenel-Audran, Annick Barbaud, Marie-Christine Ferrier-le Bouëdec, Françoise Giordano-Labadie, Brigitte Milpied, Emmanuelle Amsler, Evelyne Collet, Pascal Girardin, Angèle Soria, Julie Waton, François Truchetet, Jean-Luc Bourrain, Gwendeline Gener, Claire Bernier, Nadia Raison-Peyron
BACKGROUND: Eyelids are frequent sites of contact dermatitis. No prospective study focused on eyelid allergic contact dermatitis (EACD) has yet been published, and this topic has never been studied in French patients. OBJECTIVES: To prospectively evaluate the usefulness of an eyelid series in French patients patch tested because of EACD, and to describe these patients. METHODS: We prospectively analysed standardized data for all patients referred to our departments between September 2014 and August 2016 for patch testing for suspected EACD as the main reason...
June 8, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29882136/use-of-the-llna-brdu-elisa-for-skin-sensitization-hazard-assessment
#15
David M Lehmann
Allergic contact dermatitis (ACD) continues to be an occupational and environmental health issue. Consequently, there is a need to employ predictive tests to reduce the incidence of skin sensitization leading to clinical manifestations of ACD. For more than a decade, the murine local lymph node assay (LLNA) has been the method of choice for the identification of skin sensitizers. While the original LLNA protocol has been extensively evaluated and subjected to exhaustive validation, the use of radioisotope (i...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29881951/food-related-contact-dermatitis-contact-urticaria-and-atopy-patch-test-with-food
#16
REVIEW
Alexandra Walter, Marlene Seegräber, Andreas Wollenberg
A wide variety of foods may cause or aggravate skin diseases such as contact dermatitis, contact urticaria, or atopic dermatitis (AD), both in occupational and private settings. The mechanism of action underlying allergic disease to food, food additives, and spices may be immunologic and non-immunologic. The classification and understanding of these reactions is a complex field, and knowledge of the possible reaction patterns and appropriate diagnostic test methods is essential. In addition, certain foods may cause worsening of atopic dermatitis lesions in children...
June 7, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29881890/-when-sunscreens-do-not-help-allergic-contact-dermatitis-to-uv-filters
#17
L Ludriksone, J Tittelbach, S Schliemann, S Goetze, P Elsner
Ultraviolet (UV) filters may cause allergic and more frequently photoallergic contact dermatitis. Therefore, a photopach test should always be performed in case of a suspected contact sensitivity to UV filters. We report a case of a 65-year-old woman with a recurrent erythema of the face and décolleté after sun exposure despite application of a sunscreen. The (photo)patch test revealed a contact sensitivity to the UV filter butyl-methoxybenzoylmethane. Treatment with a topical glucocorticoid and avoidance of the particular UV filter led to a rapid improvement...
June 7, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29879253/from-probiotic-to-prebiotic-using-thermal-spring-water
#18
Joshua Zeichner, Sophie Seite
BACKGROUND: La Roche-Posay Thermal Spring Water (LRP-TSW) exhibits both probiotic and prebiotic properties enhancing the diversity of the skin microbiota. METHODS: A review was undertaken to explore the role of LRP-TSW as a topical probiotic and prebiotic therapy in improving the diversity of the skin microbiota and reducing dryness and pruritus in inflammatory skin diseases. RESULTS: The concentration of minerals and non-pathogenic microbes in LRP-TSW may explain its therapeutic benefit when used for inflammatory skin diseases...
June 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29870052/cinnamic-acid-derivatives-in-cosmetics-current-use-and-future-prospects
#19
REVIEW
Agnieszka Gunia-Krzyżak, Karolina Słoczyńska, Justyna Popiół, Paulina Koczurkiewicz, Henryk Marona, Elżbieta Pękala
Cinnamic acid derivatives are widely used in cosmetics and possess various functions. This group of compounds includes both naturally occurring as well as synthetic substances. On the basis of the Cosmetic Ingredient Database (CosIng) and available literature, this review summarizes their functions in cosmetics, including their physicochemical and biological properties as well as reported adverse effects. A perfuming function is typical of many derivatives of cinnamaldehyde, cinnamyl alcohol, dihydrocinnamyl alcohol, and cinnamic acid itself; these substances are commonly used in cosmetics all over the world...
June 5, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29863755/ph-in-nature-humans-and-skin
#20
REVIEW
Ehrhardt Proksch
The pH plays an important physiological role in nature and humans. pH varies from 1 to 8 in human organs with tight regulation in blood and epithelia of barrier organs. The physiological pH of the stratum corneum is 4.1-5.8 and several mechanisms contribute to its formation: filaggrin degradation, fatty acid content, sodium-hydrogen exchanger (NHE1) activation and melanosome release. First, the acidic pH of the stratum corneum was considered to present an antimicrobial barrier preventing colonization (e.g. by Staphylococcus aureus and Malassezia)...
June 4, 2018: Journal of Dermatology
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