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Contact dermatitis

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https://www.readbyqxmd.com/read/29656566/absence-of-human-skin-irritation-and-allergenic-potential-after-repeated-patch-applications-of-a-lamellar-moisturizer
#1
Stephanie J Nisbet
BACKGROUND: New cosmetic products should undergo clinical evaluation for skin sensitization potential. OBJECTIVES: To assess the irritation and sensitization potential of a moisturizer containing lamellar structured lipids after repeated patch application in humans, using human repeated insult patch test methodology. METHODS: This 6-week, single-center, open-label study compared a lamellar moisturizer with negative saline control in human subjects aged 18-70 years and skin phototype (Fitzpatrick) classification I-IV...
April 15, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29655482/photoallergic-contact-dermatitis-to-sunscreens-containing-oxybenzone-in-la-plata-argentina
#2
J P Russo, A Ipiña, J F Palazzolo, A B Cannavó, R D Piacentini, B Niklasson
BACKGROUND: Photoallergic contact dermatitis (PACD) to oxybenzone was reported for the first time in 1980. Oxybenzone is the most common photoallergen in the United States and Canada and the fourth most common .in Europe. There are no studies or data on the prevalence of oxybenzone PACD in Argentina. OBJECTIVE: To determine the proportion of photosensitive patients with PACD to oxybenzone. METHODS: We conducted a descriptive cross-sectional study of 35 patients with photosensitivity reactions confirmed by photopatch testing at the Research Center of Hospital Público San Martín in La Plata, Argentina, in 2015 and 2016...
April 11, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29645380/s1-guidelines-dermatoses-associated-with-dermal-lymphostasis
#3
Joachim Dissemond, Finja Jockenhöfer, Anya Miller, Günter Kurzhals, Shahrouz Noori, Stefanie Reich-Schupke, Martin Schlaeger, Erich Schubert, Markus Stücker, Tobias Weberschock, Hans Wilfried Jungkunz
The objective of the present S1 guidelines is to present current knowledge about dermatologically relevant diseases associated with localized dermal lymphostasis, thus facilitating their early detection, diagnostic workup, and targeted treatment. Whenever possible, treatment should be based on stage-appropriate and clearly defined algorithms. The numerous issues regarding differential diagnosis and treatment clinicians are confronted with in everyday clinical practice seem to warrant the publication of up-to-date guidelines...
April 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29644196/multispectral-dermatoscopic-features-of-chemical-leucoderma-with-pigmented-contact-dermatitis
#4
Balakrishnan Nirmal, Borra Santhikiran, Sramana Mukhopadhyay
Chemical leukoderma is characterized by pigment loss on constant exposure to chemical agents. Its association with pigmented contact dermatitis is rare. Here, we report a 40-year-old female presenting with depigmented macule with surrounding hyperpigmentation over the upper forehead. We used a multispectral dermatoscope by which decreased pigment network was better visualized with blue light, and gray granular dots were better appreciated with yellow light. Shorter wavelengths delineate epidermal features better whereas longer wavelengths highlight dermal features in multispectral dermatoscopy...
March 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29630166/phytophotodermatitis-induced-by-wild-parsnip
#5
Abigail L Walling, Hobart W Walling
Phytophotodermatitis results when skin is exposed to ultraviolet light after previous contact with a phototoxic compound. Wild parsnip (Pastinia sativa), a member of the Umbelliferae family, is an invasive plant species introduced to North America as a root vegetable. Although cultivated less commonly today, the plant is increasingly found growing wild in prairies and roadsides. The stems and leaves contain furocoumarins, which upon activation by UV light interact with oxygen. Resultant reactive oxygen species induce tissue damage manifesting initially as blistering and later as hyperpigmentation...
February 15, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29622382/prospective-study-of-breast-radiation-dermatitis
#6
Leah Drost, Nim Li, Danny Vesprini, Arneet Sangha, Justin Lee, Eric Leung, Eileen Rakovitch, Caitlin Yee, Edward Chow, Mark Ruschin
BACKGROUND: Despite clear benefits of radiotherapy (RT) for breast cancer, there are numerous side effects. Radiation dermatitis has a significant impact on quality of life and can result in treatment interruptions or cessation. The purpose of this study was to prospectively follow breast radiation dermatitis and determine trends including peak toxicity. PATIENTS AND METHODS: Upon initiation of RT treatment, to assess skin reaction, each patient was seen weekly by the healthcare team, or contacted via telephone to assess patient-reported symptoms...
March 15, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29613858/a-review-of-the-medical-necessity-of-comprehensive-patch-testing
#7
Tian Hao Zhu, Raagini Suresh, Erin Warshaw, Pamela Scheinman, Christen Mowad, Nina Botto, Bruce Brod, James S Taylor, Amber Reck Atwater, Kalman Watsky, Peter C Schalock, Brian C Machler, Stephen Helms, Sharon E Jacob, Jenny E Murase
Allergic contact dermatitis is associated with significant disease and economic burden in the United States. To properly manage allergic contact dermatitis, it is important to accurately identify the substance(s) implicated in the dermatitis to prevent disease recurrence. The commercially available T.R.U.E Test (36 allergens) screening panel has been reported to have a conservative hypothetical allergen detection rate of 66.0%, at most. Importantly, these calculations are based on the 78% of patients who had clinically relevant reactions to allergens present on the North American Contact Dermatitis Group screening series (70 allergens), without the use of supplemental allergens...
April 2, 2018: Dermatitis
https://www.readbyqxmd.com/read/29611499/case-report-paederus-dermatitis-in-the-returning-traveler
#8
Jacob W Pierce, Barry Rittman, Jillian E Raybould
Rash in the returned traveler can provide a diagnostic dilemma for clinicians, but a detailed history including epidemiologic exposures can allow prompt diagnosis of etiologies uncommon in the United States. One such disease is Paederus dermatitis, an irritant contact dermatitis related to exposure to the rove beetle characterized by bullous lesions with surrounding erythema. Although cases and outbreaks have commonly been reported throughout the world, they are rarely reported in travelers returning to the United States...
April 2, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29611265/allergic-contact-dermatitis-secondary-to-the-use-of-aluminium-finn-chambers%C3%A2
#9
Natalie King, Deborah Moffitt
No abstract text is available yet for this article.
May 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29611264/allergic-contact-dermatitis-from-formaldehyde-mimicking-impetigo-and-initiating-rosacea
#10
Kotryna Linauskiene, Marléne Isaksson
No abstract text is available yet for this article.
May 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29611263/allergic-contact-dermatitis-caused-by-hypersensitivity-to-gold-description-of-a-clinical-case
#11
Iwona Poziomkowska-Gęsicka, Burkhard Summer, Małgorzata Sokołowska, Peter Thomas, Michał Kurek
No abstract text is available yet for this article.
May 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29610864/association-between-use-of-acid-suppressive-medications-and-antibiotics-during-infancy-and-allergic-diseases-in-early-childhood
#12
Edward Mitre, Apryl Susi, Laura E Kropp, David J Schwartz, Gregory H Gorman, Cade M Nylund
Importance: Allergic diseases are prevalent in childhood. Early exposure to medications that can alter the microbiome, including acid-suppressive medications and antibiotics, may influence the likelihood of allergy. Objective: To determine whether there is an association between the use of acid-suppressive medications or antibiotics in the first 6 months of infancy and development of allergic diseases in early childhood. Design, Setting, and Participants: A retrospective cohort study was conducted in 792 130 children who were Department of Defense TRICARE beneficiaries with a birth medical record in the Military Health System database between October 1, 2001, and September 30, 2013, with continued enrollment from within 35 days of birth until at least age 1 year...
April 2, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29607554/anti-inflammatory-potency-testing-of-topical-corticosteroids-and-calcineurin-inhibitors-in-human-volunteers-sensitized-to-diphenylcyclopropenone
#13
Kristian F Mose, Flemming Andersen, Mads A Røpke, Lone Skov, Peter S Friedmann, Klaus E Andersen
AIM: To quantify the anti-inflammatory potency of topical corticosteroids and topical calcineurin inhibitors by measuring the contact allergic response to a diphenylcyclopropenone (DPCP) challenge in de novo sensitized human volunteers. METHODS: Two randomized, double-blind, vehicle-controlled studies were performed encompassing 76 volunteers; 29 in the first and 47 in the second studies. Topical drugs were applied pre- and/or post-treatment in block designs. The compounds were tested simultaneously under occluded patch tests covering DPCP-induced dermatitis...
April 1, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29603274/can-the-epoxides-of-cinnamyl-alcohol-and-cinnamal-show-new-cases-of-contact-allergy
#14
REVIEW
Lina Hagvall, Ida B Niklasson, Kristina Luthman, Ann-Therese Karlberg
BACKGROUND: Cinnamyl alcohol is considered to be a prohapten and prehapten with cinnamal as the main metabolite. However, many individuals who are allergic to cinnamyl alcohol do not react to cinnamal. Sensitizing epoxides of cinnamyl alcohol and cinnamal have been identified as metabolites and autoxidation products of cinnamyl alcohol. OBJECTIVE: To investigate the clinical relevance of contact allergy to epoxycinnamyl alcohol and epoxycinnamal. METHODS: Irritative effects of the epoxides were investigated in 12 dermatitis patients...
March 30, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29600821/an-unusual-presentation-of-a-common-condition-allergic-contact-dermatitis
#15
Annie Price, Natalie M Stone, Keith G Harding
Allergic contact dermatitis commonly affects patients with chronic venous leg ulcers and can contribute to impaired wound healing. Many allergens have been identified, and despite the use of advanced dressings, the incidence of allergy has remained high. We discuss an unusual presentation of allergic contact dermatitis in a patient with a chronic wound. The patient's history was consistent with a recurrent venous leg ulcer, but on this occasion, the wound continued to deteriorate despite optimal treatment. This prompted further investigation, which included patch testing...
March 30, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29600560/contact-sensitivity-in-patients-with-venous-leg-ulcer-a-multi-centric-indian-study
#16
Reena Rai, Manjunath M Shenoy, Vishalakshi Viswanath, Nilendu Sarma, Imran Majid, Sunil Dogra
Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to the poor ulcer healing. To detect the various contact sensitisers in patients with venous leg ulcers through patch testing, patients from 6 centres across India with venous leg ulcers of longer than 6 weeks duration were enrolled for the study...
March 30, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29598994/allergic-contact-dermatitis-due-to-methyl-glucose-dioleate-in-a-balm-cream
#17
T Sanz-Sánchez, R M Díaz-Díaz, C Garrido Gutiérrez, V Leis Dosil
No abstract text is available yet for this article.
March 26, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29596730/differential-diagnoses-of-diaper-dermatitis
#18
Regina Fölster-Holst
Diaper dermatitis is the most common contact eczema present in early childhood. The main cause is an irritant reaction to urine and feces, which is facilitated by the occlusive conditions under the diaper, leading to hyperhydration of the stratum corneum (diaper dermatitis). In addition, diaper pressure and friction can increase the risk of skin inflammation, which also opens the skin up to other irritant agents, allergens, and infectious agents, such as candida albicans. However, a variety of diseases are associated with inflammation of the skin in the diaper region, therefore the term "diaper dermatitis" is merely descriptive and does not reflect anything about the etiopathogenesis...
March 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29578888/occupational-contact-dermatitis-in-the-canadian-aircraft-industry-a-25-year-retrospective-study
#19
Camille Loranger, Linda Moreau, Denis Sasseville
BACKGROUND: Aircraft building exposes workers to irritant and sensitizing products. OBJECTIVE: The aim of this article was to study occupational dermatoses among aircraft workers over 25 years. METHODS: The files of aerospace workers referred between 1990 and 2015 were extracted from the database of the McGill University Health Centre contact dermatitis clinic. These were subdivided according to demographics, type of work, patch testing results, and final diagnosis...
March 24, 2018: Dermatitis
https://www.readbyqxmd.com/read/29578626/both-children-and-adult-patients-with-difficult-to-treat-atopic-dermatitis-have-high-prevalences-of-concomitant-allergic-contact-dermatitis-and-are-frequently-polysensitized
#20
M Boonstra, T Rustemeyer, M A Middelkamp-Hup
BACKGROUND: Concomitant allergic contact dermatitis (ACD) has been described as a possible cause of atopic dermatitis (AD) becoming difficult-to-treat. However, contact sensitization in this patient group has barely been studied. OBJECTIVE: To study the occurrence of ACD in a population of difficult-to-treat AD children and adults. METHODS: Clinical and patch test information of 48 patients with difficult-to-treat AD unresponsive to conventional out-patient treatments was gathered retrospectively...
March 26, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
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