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Contact dermatitis

E Proksch, D Dähnhardt, S Dähnhardt-Pfeiffer, R Fölster-Holst
The permeability barrier plays an important role in numerous skin diseases. Particularly well known is the importance of this barrier in eczema. In irritative-toxic contact dermatitis, the first step in the pathogenesis is the disturbance of the permeability barrier by irritative-toxic noxious substances. Only after damage to the barrier is achieved can irritants and allergens penetrate into the living epidermis. In atopic eczema due to an impaired barrier, allergens penetrate from the environment into the skin and cause or worsen the eczema...
October 21, 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Gabriel Chia Shi Zhe, Andrew Green, Yuke Tien Fong, Haur Yueh Lee, Sweet Far Ho
Sodium hypochlorite is a clear yellowish solution with a characteristic odour of chlorine and is commonly used as a disinfectant and a bleaching agent. It is used in various healthcare settings for its fast-acting and broad-spectrum antimicrobial activity. It is a known irritant and there are some reports that it can also cause allergic contact dermatitis of type IV hypersensitivity. We report a case of work-related type I hypersensitivity to sodium hypochlorite, presenting with recurrent urticarial rash and a positive prick test reaction to this chemical...
October 21, 2016: BMJ Case Reports
Giuseppe Ruggiero, Claudia Carnevale, Andrea Diociaiuti, Fabio Arcangeli, May El Hachem
BACKGROUND: Contact dermatitis can be defined as an inflammatory process affecting the skin surface and induced by contact with chemical, physical and/or biotic agents in the environment. It causes lesions to skin, mucosae and semi-mucosae by means of allergic and irritant pathogenic mechanisms. Among the main triggers of contact dermatitis in the pediatric age are chemical or physical agents, which cause irritant contact dermatitis (ICD), and sensitizers, which cause a tissue damage through an allergic mechanism (allergic contact dermatitis [ACD])...
December 2016: Minerva Pediatrica
Malin Engfeldt, Lina Hagvall, Marléne Isaksson, Mihály Matura, Martin Mowitz, Kristina Ryberg, Berndt Stenberg, Cecilia Svedman, Magnus Bruze
BACKGROUND: In 2014, the fragrance hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) was excluded from the Swedish baseline series. OBJECTIVES: To study (i) whether fragrance mix (FM) II with 5% HICC detects more positive reactions than FM II with 2.5% HICC, and (ii) the reproducibility of patch testing with HICC. METHODS: Two thousand one hundred and eighteen dermatitis patients at five Swedish dermatology departments were consecutively tested with FM II 14% pet...
October 21, 2016: Contact Dermatitis
Ayca Aktas Sukuroglu, Dilek Battal, Sema Burgaz
BACKGROUND: Henna has a very low allergic potential, and severe allergic contact dermatitis is mainly caused by p-phenylenediamine (PPD), which is added to temporary black 'henna tattoos', and potentially also by some heavy metals. OBJECTIVE: To determine the presence of, and quantify, Lawsone, PPD and heavy metal contaminants (cobalt, nickel, lead, and chromium) in commercial temporary black henna tattoo mixtures (n = 25) sold in Turkey. METHODS: Lawsone and PPD concentrations were analysed with high-performance liquid chromatography, and heavy metal quantification was performed with inductively coupled plasma mass spectrometry...
October 19, 2016: Contact Dermatitis
James Raymond, Joseph Konya, Sophie Bakis-Petsoglou
No abstract text is available yet for this article.
September 2016: JAAD Case Reports
Sakine Işik, Sule Caglayan-Sözmen, Özden Anal, Özkan Karaman, Nevin Uzuner
Allergic contact reactions to hair dyes arise mostly due to sensitization to para-phenylenediamine (PPD). Para-phenylenediamine, a derivative of p-nitroanaline, is widely used as an oxydizable hair dye and is also found in black henna tattoo. Subsequent exposure to PPD may lead to delayed type IV hypersensitivity reaction manifesting as acute contact dermatitis. Here, a 15-year-old girl is presented, who developed a hypersensitivity reaction after first exposure to hair dye. She was found to have been sensitized to PPD before, through application of black henna tatto...
October 4, 2016: Pediatric Emergency Care
Giovanna Luongo, Francesco Iadaresta, Emanuele Moccia, Conny Östman, Carlo Crescenzi
A simple method for simultaneous determination of twenty-one analytes, belonging to two classes of compounds, aromatic amines and quinolines, is presented. Several of the analytes considered in this study frequently occur in textiles goods on the open market and have been related to allergic contact dermatitis and/or are proven or suspected carcinogens. The method includes an efficient clean-up step using graphitized carbon black (GCB) that simplifies and improves the robustness of the subsequent GC-MS analysis...
September 29, 2016: Journal of Chromatography. A
Annick Barbaud, Julie Waton
Systemic hypersensitivity (HS) to corticosteroids (CS) is paradoxical but does exist. Some patients with a previous contact allergy to topical CS may develop a systemic contact dermatitis (SCD) while receiving CS orally or intravenously. However, a previous contact sensitization is not mandatory for developing a systemic HS to CS. Acute or delayed urticaria can occur in immediate HS. Immediate HS can be due to excipients, mainly carboxymethylcellulose or to CS themselves. Delayed reactions, mainly maculopapular rash and acute generalized exanthematous pustulosis can occur...
October 12, 2016: Current Pharmaceutical Design
N Milanesi, G Bartolini, S Francalanci, M Gola
Dimethyl fumarate (DMF), the methyl ester form of fumaric acid (DMF) is an effective mold-growth inhibitor. It has a wide-spectrum biocide activity and has been used to protect leather during storage and transport. DMF was first identified as a potent contact sensitizer during a contact dermatitis outbreak that occurred because of its use in Chinese manufactured furniture (1,2). This article is protected by copyright. All rights reserved.
October 14, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Ellen P Carlin, Nichole Giller, Rebecca Katz
OBJECTIVE: To quantify the population at risk of serious adverse reactions to replicating smallpox vaccine. DESIGN AND SAMPLE: Conditions known or suspected to carry risk were identified via Centers for Disease Control and Prevention planning documents, other federal publications, and peer-reviewed literature. Conditions identified were categorized as historically recognized risks or more recently recognized immunocompromised states that may pose risk. Major historical risk factors were as follows: eczema/atopic dermatitis, pregnancy, HIV, and primary immunodeficiency...
October 13, 2016: Public Health Nursing
Aayush Gupta, Yugal K Sharma, Kirti Deo
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
Massimo Vaia, Stefania Petrosino, Daniele De Filippis, Luana Negro, Andrea Guarino, Rosa Carnuccio, Vincenzo Di Marzo, Teresa Iuvone
In mice, 2,4-dinitrofluorobenzene (DNFB) induces contact allergic dermatitis (CAD), which, in a late phase, is characterized by mast cell (MC) infiltration and angiogenesis. Palmitoylethanolamide (PEA), an endogenous anti-inflammatory molecule, acts by down-modulating MCs following activation of the cannabinoid CB2 receptor and peroxisome proliferator-activated receptor-α (PPAR-α). We have previously reported the anti-inflammatory effect of PEA in the early stage of CAD. Here, we examined whether PEA reduces the features of the late stage of CAD including MC activation, angiogenesis and itching...
October 5, 2016: European Journal of Pharmacology
Alicia R Mathers, Cara D Carey, Meaghan E Killeen, Julio Diaz-Perez, Sonia R Salvatore, Francisco J Schopfer, Bruce A Freeman, Louis D Falo
BACKGROUND: Reactions between nitric oxide (NO), nitrite (NO2(-) ), and unsaturated fatty acids give rise to electrophilic nitro-fatty acids (NO2 -FAs), such as nitro-oleic acid (OA-NO2 ) and nitro-linoleic acid (LNO2 ). Endogenous electrophilic fatty acids (EFAs) mediate anti-inflammatory responses by modulating metabolic and inflammatory signal transduction reactions. Hence, there is considerable interest in employing NO2 -FAs and other EFAs for the prevention and treatment of inflammatory disorders...
October 8, 2016: Allergy
Ayano Umekoji, Kazuyoshi Fukai, Junko Sowa-Osako, Marina Manabe, Maki Kikugawa, Kyoko Ishii, Kazumi Sasaki, Daisuke Tsuruta
No abstract text is available yet for this article.
November 2016: Contact Dermatitis
S W J de Gier, H J Stenveld, R E J Roach, E R Mutsaers, M B Maessen-Visch
No abstract text is available yet for this article.
November 2016: Contact Dermatitis
Sibylle Schliemann, Marléne Isaksson, Christina Persson, Magnus Bruze, Jörg Tittelbach, Peter Elsner
No abstract text is available yet for this article.
November 2016: Contact Dermatitis
Niels H Bennike, Jeanne D Johansen, Claus Zachariae
No abstract text is available yet for this article.
November 2016: Contact Dermatitis
Ravinder Atkar, Pamela Todd
No abstract text is available yet for this article.
November 2016: Contact Dermatitis
Tanja K Carøe, Niels E Ebbehøj, Tove Agner
BACKGROUND: Hairdressers are at risk of developing occupational contact dermatitis because of their intense contact with wet work in combination with chemicals. OBJECTIVES: To perform an analysis of a cohort study of hairdressers with occupational contact dermatitis recognized in the period 2006-2011, focusing on individual and environmental factors associated with the disease. METHODS: The study was a descriptive, register-based survey including all hairdressers with recognized occupational contact dermatitis in Denmark in the period January 2006 to September 2011...
October 6, 2016: Contact Dermatitis
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