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https://www.readbyqxmd.com/read/28527023/-high-resolution-manometry-of-pharyngeal-swallowing-dynamics
#1
REVIEW
M Jungheim, M Ptok
BACKGROUND: To transport a bolus from the mouth into the stomach, regular contraction of the pharyngeal muscles and a coordinated function of the upper esophageal sphincter (UES) are necessary. The muscle contraction generates intraluminal pressure, which pushes the bolus continuously forward. In contrast to imaging studies, manometric methods enable assessment of intraluminal pressure buildup and the function of the muscles involved. These methods were initially established for the esophagus and have been used increasingly in the pharynx for 7-8 years...
May 19, 2017: HNO
https://www.readbyqxmd.com/read/28523360/comparison-of-the-multichannel-intraluminal-impedance-ph-and-conventional-ph-for-measuring-esophageal-acid-exposure-a-propensity-score-matched-analysis
#2
Masato Hoshino, Nobuo Omura, Fumiaki Yano, Kazuto Tsuboi, Se Ryung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Hideyuki Kashiwagi, Katsuhiko Yanaga
BACKGROUND: The modalities for evaluating acid reflux in medical care for gastroesophageal reflux disease (GERD) include conventional pH (C-pH), wireless pH (Bravo(®)) and multichannel intraluminal impedance pH (MII-pH), which have been reported to vary with respect to the duration of acid reflux. In this study, we examined the difference between the acid reflux in C-pH and MII-pH among patients with GERD. METHODS: Prior to initial laparoscopic fundoplication carried out on 297 cases from December 1994 to April 2016, an upper gastrointestinal endoscopy and C-pH or MII-pH were conducted...
May 18, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28522664/non-contrast-enhanced-silent-scan-mr-angiography-of-intracranial-anterior-circulation-aneurysms-treated-with-a-low-profile-visualized-intraluminal-support-device
#3
N Takano, M Suzuki, R Irie, M Yamamoto, K Teranishi, K Yatomi, N Hamasaki, K K Kumamaru, M Hori, H Oishi, S Aoki
BACKGROUND AND PURPOSE: The Low-Profile Visualized Intraluminal Support Device comprises a small-cell nitinol structure and a single-wire braided stent that provides greater metal coverage than previously reported intracranial stents, as well as assumed strong susceptibility artifacts. This study aimed to assess the benefits of non-contrast-enhanced MRA by using a Silent Scan (Silent MRA) for intracranial anterior circulation aneurysms treated with Low-Profile Visualized Intraluminal Support Device stents...
May 18, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28521919/intravascular-ultrasound-analysis-of-intraplaque-versus-subintimal-tracking-in-percutaneous-intervention-for-coronary-chronic-total-occlusions-and-association-with-procedural-outcomes
#4
Lei Song, Akiko Maehara, Matthew T Finn, Sanjog Kalra, Jeffrey W Moses, Manish A Parikh, Ajay J Kirtane, Michael B Collins, Tamim M Nazif, Khady N Fall, Raja Hatem, Ming Liao, Tiffany Kim, Philip Green, Ziad A Ali, Candido Batres, Martin B Leon, Gary S Mintz, Dimitri Karmpaliotis
OBJECTIVES: Using intravascular ultrasound (IVUS), the authors compared outcomes by observed wire position (intraplaque vs. subintimal) achieved during successful chronic total occlusion (CTO) lesion treatment. BACKGROUND: Recent successes in CTO percutaneous coronary intervention (PCI) have used both intraluminal and subintimal wire tracking to improve procedural success. IVUS may be used to determine the course of wire tracking after crossing a CTO. METHODS: From March 2014 to March 2016, data were collected into a single-center database from 219 patients undergoing CTO PCI with concomitant IVUS imaging...
May 22, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28516221/small-bowel-obstruction-due-to-ingestion-of-rubber-balls
#5
Alaa N Alsharief, Christopher Blackmore, Pierre Schmit
We report a case of a 10-month-old girl who presented with a 10-day history of emesis that became bilious on the last day. The initial evaluation suggested small bowel obstruction. An upper gastrointestinal study confirmed the normal location of the duodenojejunal junction with normal rotation and no evidence of midgut volvulus. Ultrasound (US) evaluation demonstrated two intraluminal lesions that do not follow the typical features of solid or cystic lesions. Two rubber balls were found at surgery to be responsible for the small bowel obstruction...
May 17, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28513477/microtube-array-membrane-bioreactor-promotes-neuronal-differentiation-and-orientation
#6
Sabrina Morelli, Antonella Piscioneri, Simona Salerno, Chien-Chung Chen, Chee Ho Chew, Lidietta Giorno, Enrico Drioli, Loredana De Bartolo
An important challenge in neuronal tissue engineering is to create innovative tools capable of promoting cellular response in terms of neuronal differentiation and neurite orientation that may be used as investigational platforms for studying neurobiological events and neurodegenerative disorders. A novel membrane bioreactor was created to provide a 3D well-controlled microenvironment for neuronal outgrowth. The bioreactor consisted of poly-L-lactic acid highly aligned microtube array (PLLA-MTA) membranes assembled in parallel within a chamber that establish an intraluminal and an extraluminal compartment whose communication occurs through the pores of the MTA membrane walls...
May 17, 2017: Biofabrication
https://www.readbyqxmd.com/read/28508867/bloating-and-abdominal-distension-old-misconceptions-and-current-knowledge
#7
REVIEW
Juan R Malagelada, Anna Accarino, Fernando Azpiroz
Bloating, as a symptom and abdominal distension, as a sign, are both common functional-type complaints and challenging to manage effectively. Individual patients may weight differently the impact of bloating and distension on their well-being. Complaints may range from chronic highly distressing pain to simply annoying and unfashionable protrusion of the abdomen. To avoid mishaps, organic bloating, and distension should always be considered first and appropriated assessed. Functional bloating and distension often present in association with other manifestations of irritable bowel syndrome or functional dyspepsia and in that context patients tend to regard them as most troublesome...
May 16, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28506000/therapeutic-effects-of-oral-dimethyl-fumarate-on-stroke-induced-by-middle-cerebral-artery-occlusion-an-animal-experimental-study
#8
Anahid Safari, Mehdi Fazeli, Mohammad Reza Namavar, Nader Tanideh, Peyman Jafari, Afshin Borhani-Haghighi
BACKGROUND: Dimethyl fumarate (DMF) has immune-modulatory and neuro-protective characteristics that can be used for treatment of acute ischemic stroke. OBJECTIVE: To investigate the therapeutic effects of DMF on histological and functional recovery of rats after transient middle cerebral artery (MCA) occlusion. METHODS: 22 Sprague-Dawley male rats weighing 275-300 g were randomized into three groups by block randomization. In the sham group (n = 7), the neck was opened, but neither MCA was occluded, nor any drug was administered...
May 9, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28502834/a-rare-case-of-intravesical-angiomyofibroblastoma
#9
Phanindra Mohan Deka, Jaynil A Bagawade, Pallavi Deka, Ronica Baruah, Naushad Shah
OBJECTIVES: To study the first reported case of intravesical Angiomyofibroblastoma (AMFB). AMFB is an uncommon benign mesenchymal lesion, mostly described in the lower female genital tract, especially in the vulva and less commonly the vagina. It is rarely seen in the male genital tract. The importance of this rare neoplasm is related to its potential mimicry of more infiltrative and prognostically less favorable lesions, such as aggressive angiomyxomas, that are found in the same anatomic area...
May 11, 2017: Urology
https://www.readbyqxmd.com/read/28501910/targeting-the-dominant-mechanism-of-coronary-microvascular-dysfunction-with-intracoronary-physiology-tests
#10
REVIEW
Hernán Mejía-Rentería, Nina van der Hoeven, Tim P van de Hoef, Julius Heemelaar, Nicola Ryan, Amir Lerman, Niels van Royen, Javier Escaned
The coronary microcirculation plays a key role in modulating blood supply to the myocardium. Several factors like myocardial oxygen demands, endothelial and neurogenic conditions determine its function. Although there is available evidence supporting microvascular dysfunction as an important cause of myocardial ischaemia, with both prognostic and symptomatic implications, its diagnosis and management in clinical practice is still relegated to a second plane. Both diagnostic and therapeutic approaches are hampered by the broadness of the concept of microvascular dysfunction, which fails addressing the plurality of mechanisms leading to dysfunction...
May 13, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28499904/completely-thrombosed-distal-middle-cerebral-artery-aneurysm-mimicking-a-cavernous-angioma-case-report-and-review-of-the-literature
#11
Sokol Trungu, Placido Bruzzaniti, Stefano Forcato, Marco Cimatti, Antonino Raco
BACKGROUND: Distal middle cerebral artery (MCA) aneurysms originate from branches of MCA distal to its main bifurcation or the peripheral branches. Distal MCA aneurysms are uncommon compared to saccular aneurysms developing along the proximal trunks of MCA. However, thrombotic aneurysms, characterized by organized intraluminal thrombus and solid mass, are frequently in the large and giant size range, while complete thrombosis of non-giant MCA aneurysms is very rare. CASE PRESENTATION: We present the clinical case of a 53 years-old woman with a completely thrombosed medium distal MCA aneurysm which mimics a cavernous angioma...
May 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28499815/new-insight-into-the-interaction-of-traf2-c-terminal-domain-with-lipid-raft-microdomains
#12
Arianna Ceccarelli, Almerinda Di Venere, Eleonora Nicolai, Anastasia De Luca, Nicola Rosato, Enrico Gratton, Giampiero Mei, Anna Maria Caccuri
In this study we provide the first evidence of the interaction of a truncated-TRAF2 with lipid raft microdomains. We have analyzed this interaction by measuring the diffusion coefficient of the protein in large and giant unilamellar vesicles (LUVs and GUVs, respectively) obtained both from synthetic lipid mixtures and from natural extracts. Steady-state fluorescence measurements performed with synthetic vesicles indicate that this truncated form of TRAF2 displays a tighter binding to raft-like LUVs with respect to the control (POPC-containing LUVs), and that this process depends on the protein oligomeric state...
May 9, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28497033/intrapulmonary-percussive-ventilation-as-an-airway-clearance-technique-during-venoarterial-extracorporeal-life-support-in-an-infant-with-pertussis
#13
Conrad Krawiec, Ken Ballinger, E Scott Halstead
Initiation of extracorporeal life support (ECLS) is often followed by complete opacification of pulmonary parenchyma and volume loss. The optimal mechanical ventilator management and lung recruitment strategy of a pediatric patient requiring extracorporeal membrane oxygenation is not known. We present a case of a 4-week old infant who developed a severe pertussis infection requiring ECLS. The severity of his illness and pertussis infection-associated intraluminal bronchiole obstruction made medical management challenging...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28497006/under-pressure-intraluminal-filling-pressures-of-postpartum-hemorrhage-tamponade-balloons
#14
Kathleen M Antony, Diana A Racusin, Michael A Belfort, Gary A Dildy
Objective Uterine tamponade by fluid-filled balloons is now an accepted method of controlling postpartum hemorrhage. Available tamponade balloons vary in design and material, which affects the filling attributes and volume at which they rupture. We aimed to characterize the filling capacity and pressure-volume relationship of various tamponade balloons. Study Design Balloons were filled with water ex vivo. Intraluminal pressure was measured incrementally (every 10 mL for the Foley balloons and every 50 mL for all other balloons)...
April 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28495950/carotid-bulb-webs-as-a-cause-of-cryptogenic-ischemic-stroke
#15
P I Sajedi, J N Gonzalez, C A Cronin, T Kouo, A Steven, J Zhuo, O Thompson, R Castellani, S J Kittner, D Gandhi, P Raghavan
BACKGROUND AND PURPOSE: Carotid webs are intraluminal shelf-like filling defects at the carotid bulb with recently recognized implications in patients with recurrent ischemic stroke. We sought to determine whether carotid webs are an under-recognized cause of "cryptogenic" ischemic stroke and to estimate their prevalence in the general population. MATERIALS AND METHODS: A retrospective review of neck CTA studies in young patients with cryptogenic stroke over the past 6 years (n = 33) was performed to determine the prevalence of carotid webs compared with a control group of patients who received neck CTA studies for reasons other than ischemic stroke (n = 63)...
May 11, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28495303/the-characteristics-of-salivary-pepsin-in-patients-with-severe-motor-and-intellectual-disabilities
#16
Naoki Hashizume, Suguru Fukahori, Kimio Asagiri, Shinji Ishii, Nobuyuki Saikusa, Naruki Higashidate, Motomu Yoshida, Daisuke Masui, Saki Sakamoto, Yoshiaki Tanaka, Minoru Yagi, Yushiro Yamashita
PURPOSE: The aim of the present study was to determine the utility of measuring the salivary pepsin level (SPL) as an objective assessment of gastroesophageal reflux disease (GERD) in severe motor and intellectual disabilities (SMID) patients. SUBJECTS AND METHODS: This prospective study included 26 SMID patients who underwent simultaneous 24-h multichannel intraluminal impedance pH measurement (pH/MII) and SPL evaluation. The enrolled patients were divided into GERD (+) or GERD (-) groups according to the pH/MII findings...
May 8, 2017: Brain & Development
https://www.readbyqxmd.com/read/28493535/the-mongolian-gerbil-meriones-unguiculatus-as-a-model-for-inflammationpromoted-prostate-carcinogenesis
#17
Amado A Quintar, Bianca F Gonçalves, Sebastião R Taboga, Cristina A Maldonado
One of the recognized issues in prostate cancer research is the lack of animal models allowing the research of pathological, biochemical, and genetic factors in immunocompetent animals. Our research group has successfully employed the gerbil in several studisfor prostate diseases. In the present work, we aimed to analyze the effect of chronic bacterial inflammation on MNU-induced prostate carcinogenesis in gerbils Histopathological assessment of the prostatic complex revealed that treatment combinations with MNU plus testosterone or bacterial infection resulted in a promotion of prostate cancer, with bacterial inflammation being more effective in increasing premalignant and malignant tissular alterations than testosterone in the prostate...
May 11, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28492149/the-histopathological-parameters-affecting-biochemical-recurrence-in-radical-prostatectomies
#18
Yelda Dere, Aysegu Aksoy Altinboga, Kaan Bal, Aylin Calli, Murat Ermete, Aysegul Akder Sari
OBJECTIVE: To determine the relationship between biochemical recurrence and other histopathological factors in prostate cancer. STUDY DESIGN: Analytical study. PLACE AND DURATION OF STUDY: Pathology and Urology Departments, Izmir Ataturk Training and Research Hospital, between 2001 - 2013. METHODOLOGY: 117 cases diagnosed with prostatic adenocarcinoma and treated by radical prostatectomy were reviewed retrospectively for histopathological features; whereas, other prognostic findings were noted...
April 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28488811/resolution-of-occlusive-carotid-artery-thrombus-treated-with-anticoagulation-as-demonstrated-on-duplex-ultrasonography
#19
Laura Stein, John W Liang, Jesse Weinberger
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid atherosclerosis. Identification of nonatherosclerotic thrombus as the cause of the carotid occlusive disease can obviate the need for an interventional procedure, and resolution of thrombus can be monitored with B-mode duplex ultrasonography. METHODS: We reviewed 3 patients treated on The Mount Sinai Hospital Stroke Unit with anticoagulation for nonatherosclerotic carotid thrombi and followed with serial Doppler ultrasonogrpahy for resolution of thrombus...
May 10, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28488729/randomized-clinical-trial-of-biodegradeable-intraluminal-sheath-to-prevent-anastomotic-leak-after-stapled-colorectal-anastomosis
#20
I S Bakker, A N Morks, H O Ten Cate Hoedemaker, J G M Burgerhof, H G Leuvenink, J B van Praagh, R J Ploeg, K Havenga
BACKGROUND: Anastomotic leakage is a potential major complication after colorectal surgery. The C-seal was developed to help reduce the clinical leakage rate. It is an intraluminal sheath that is stapled proximal to a colorectal anastomosis, covering it intraluminally and thus preventing intestinal leakage in case of anastomotic dehiscence. The C-seal trial was initiated to evaluate the efficacy of the C-seal in reducing anastomotic leakage in stapled colorectal anastomoses. METHODS: This RCT was performed in 41 hospitals in the Netherlands, Germany, France, Hungary and Spain...
May 10, 2017: British Journal of Surgery
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