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https://www.readbyqxmd.com/read/28925899/effect-of-androgen-deprivation-therapy-adt-on-bone-health-status-in-men-with-prostate-cancer
#1
Nur Vaizura Mohamad, Ima Nirwana Soelaiman, Kok Yong Chin
Backgraoung and Objective: Prostate cancer is the most prevalent non-cutaneous cancer in men, which causes significant mortality among the patients. Since prostate cancer cells are stimulated by androgen, effective androgen ablation in men is one of the essential strategies in the management of prostate cancer. DISCUSSION: Several treatment options are available for different stages of prostate cancer. Hormone therapy known as androgen deprivation therapy (ADT) is the first line treatment used to treat advanced prostate cancer...
September 18, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28924690/lateral-fixation-an-alternative-surgical-approach-in-the-prevention-of-complete-atypical-femoral-fractures
#2
Mohammad Kharazmi, Karl Michaëlsson, Pär Hallberg, Jörg Schilcher
Little evidence is available on how to treat incomplete atypical fractures of the femur. When surgery is chosen, intramedullary nailing is the most common invasive technique. However, this approach is adopted from the treatment of other types of ordinary femoral fracture and does not aim to prevent the impending complete fracture by interrupting the mechanism underlying the pathology. We suggest a different surgical approach that intends to counteract the underlying biomechanical conditions leading to a complete atypical fracture and thus could be better suited in selected cases...
September 18, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28920780/use-of-composite-materials-as-a-component-of-tusk-fracture-management-in-an-asian-elephant-elephas-maximus-and-an-african-elephant-loxodonta-africana
#3
Richard R Sim, Elizabeth Stringer, Dennis Donovan, Rachael Chappell, Pat Flora, Jon Hall, Selvum Pillay, Benjamin G Willis, Stephanie McCain
Tusk fractures in Asian (Elephas maximus) and African elephants (Loxodonta africana) can result in damage to the distal end or to longitudinal cracks, potentially progressing to pulpitis. With pulp exposure, endodontic therapy is the treatment of choice, but conservative therapy has sufficed for some elephants. This manuscript describes the use of composite materials as a component of tusk fracture management. A 7-yr-old male Asian elephant fractured the distal end of both tusks with pulp exposure in one. Capping of each tusk with a Kevlar/fiberglass composite prevented further damage, and a modification allowed care of the exposed pulp tissue...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28919380/establishing-a-hospital-based-fracture-liaison-service-to-prevent-secondary-insufficiency-fractures
#4
REVIEW
Shahryar Noordin, Salim Allana, Bassam A Masri
Insufficiency fracture care requires more than surgery to ensure rapid and strong union with diminished chance of future fractures. The FLS program provides an opportunity to treat osteoporosis from a public health perspective rather than leaving this to the whims of individual physicians. This is achieved by providing a seamless integration of care by health care providers, nursing staff and administration. The FLS can be adapted to any model of care including academic health systems. FLS provides a holistic approach to identify patients as well as to provide evidence-based interventions to prevent subsequent fractures...
September 12, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28919185/epidemiology-of-cervical-spine-injuries-in-high-school-athletes-over-a-ten-year-period
#5
Adele Meron, Christopher McMullen, Scott R Laker, Dustin Currie, R Dawn Comstock
BACKGROUND: Over 7 million athletes participate in high school (HS) sports annually, with both the benefits of physical activity and risks of injury. While catastrophic cervical spine injuries have been studied, limited data are available characterizing less severe cervical spine injuries in HS athletes. OBJECTIVE: To describe and compare cervical spine injury rates and patterns among United States (US) HS athletes across 24 sports over a ten-year period. DESIGN: Descriptive epidemiology study SETTING: National sample of high schools participating in the High School Reporting Information Online (High School RIO) injury surveillance system...
September 12, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28918771/falls-in-hospitalized-geriatric-psychiatry-patients-high-incidence-but-only-a-few-fractures
#6
Dennis Oepen, Tim Fleiner, Andrés Oliva Y Hausmann, Susanne Zank, Wiebren Zijlstra, Peter Haeussermann
Fall rates from 3.2 to 17.1 falls per 1,000 hospital days in geriatric psychiatry facilities have been reported to date. Up to 5% of the falls result in severe injuries, but data concerning medical consequences are scare. This brief report presents a retrospective analysis of one year fall protocols from a geriatric psychiatry department focusing on consequences of falls. Fall-induced injuries were rated in four categories: no injuries, mild injuries (contusions, hematomas, abrasions), moderate injuries (lacerations, dislocations), and severe injuries (fractures, cerebral hemorrhages)...
September 18, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28916915/inflammatory-diseases-and-bone-fragility
#7
REVIEW
K Briot, P Geusens, I Em Bultink, W F Lems, C Roux
Systemic osteoporosis and increased fracture rates have been described in chronic inflammatory diseases such as rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, inflammatory bowel diseases, and chronic obstructive pulmonary disease. Most of these patients receive glucocorticoids, which have their own deleterious effects on bone. However, the other main determinant of bone fragility is the inflammation itself, as shown by the interactions between the inflammatory mediators, the actors of the immune system, and the bone remodelling...
September 15, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28916290/conceptualizing-a-dynamic-fall-risk-model-including-intrinsic-risks-and-exposures
#8
Jochen Klenk, Clemens Becker, Pierpaolo Palumbo, Lars Schwickert, Kilan Rapp, Jorunn L Helbostad, Chris Todd, Stephen R Lord, Ngaire Kerse
Falls are a major cause of injury and disability in older people, leading to serious health and social consequences including fractures, poor quality of life, loss of independence, and institutionalization. To design and provide adequate prevention measures, accurate understanding and identification of person's individual fall risk is important. However, to date, the performance of fall risk models is weak compared with models estimating, for example, cardiovascular risk. This deficiency may result from 2 factors...
September 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28913325/bone-loss-prevention-of-bisphosphonates-in-patients-with-inflammatory-bowel-disease-a-systematic-review-and-meta-analysis
#9
REVIEW
Yan Hu, Xiaoting Chen, Xiaojing Chen, Shuang Zhang, Tianyan Jiang, Jing Chang, Yanhong Gao
OBJECTIVE: The purpose of this study was to evaluate the effect of bisphosphonates in improving bone mineral density (BMD) and decreasing the occurrence rate of fractures and adverse events in patients with inflammatory bowel disease (IBD). METHODS: Randomized controlled trials (RCTs) which use bisphosphonates in IBD patients were identified in PubMed, MEDLINE database, EMBASE database, Web of Knowledge, and the Cochrane Databases between 1990 and June 2016. People received bisphosphonate or placebos with a follow-up of at least one year were also considered...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28913315/the-algorithm-oriented-management-of-nasal-bone-fracture-according-to-stranc-s-classification-system
#10
Ki-Sung Park, Seung-Soo Kim, Wu-Seop Lee, Wan-Suk Yang
BACKGROUND: Nasal bone fracture is one of the most common facial bone fracture types, and the surgical results exert a strong influence on the facial contour and patient satisfaction. Preventing secondary deformity and restoring the original bone state are the major goals of surgeons managing nasal bone fracture patients. In this study, a treatment algorithm was established by applying the modified open reduction technique and postoperative care for several years. METHODS: This article is a retrospective chart review of 417 patients who had been received surgical treatment from 2014 to 2015...
June 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28913306/silicone-implant-sandwiched-between-intact-nasal-bones-with-fractured-nasal-bone-segments
#11
Soo Hyun Woo, Woo Seob Kim, Han Koo Kim, Tae Hui Bae
As the number of people who have undergone augmentation rhinoplasty has increased recently, nasal fractures are becoming more common after rhinoplasty. A silicone implant can affect the nasal fracture pattern, but there is no significant difference in treatment methods commonly. A 28-year-old female who had undergone augmentation visited our clinic with a nasal fracture. Computed tomography revealed that the silicone implant was sandwiched between the intact nasal bones with fractured bone fragments. In this case, open reduction was inevitable and a new silicone implant was inserted after reduction...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28912754/the-gambian-bone-and-muscle-ageing-study-baseline-data-from-a-prospective-observational-african-sub-saharan-study
#12
Ayse Zengin, Anthony J Fulford, Yankuba Sawo, Landing M Jarjou, Inez Schoenmakers, Gail Goldberg, Ann Prentice, Kate A Ward
The Gambian Bone and Muscle Ageing Study is a prospective observational study investigating bone and muscle ageing in men and women from a poor, subsistence farming community of The Gambia, West Africa. Musculoskeletal diseases, including osteoporosis and sarcopenia, form a major part of the current global non-communicable disease burden. By 2050, the vast majority of the world's ageing population will live in low- and middle-income countries with an estimated two-fold rise in osteoporotic fracture. The study design was to characterise change in bone and muscle outcomes and to identify possible preventative strategies for fracture and sarcopenia in the increasing ageing population...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28912393/-cost-effectiveness-of-implementing-osteoporosis-liaison-service-program
#13
Kensuke Moriwaki
Facing with swelling medical expenses, bringing a viewpoint of cost-effectiveness to disease management of osteoporosis has become important. Previous economic evaluations from the UK and the USA have reported that implementing a Fracture Liaison Service program reduces refracture rates and results in healthcare cost-savings. In recent years, a model-based cost-effectiveness analysis has been performed in Japan and reported Secondary fracture prevention by Osteoporosis Liaison Service program is cost-effective in Japanese women with osteoporosis who have suffered a hip fracture...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912392/-refracture-prevention-and-rehabilitation
#14
Hiroaki Fujita
Osteoporosis Liaison Service(OLS)is not only the fracture prevention of the onset, and the refracture prevention holds important positioning. For OLS activity in the hospitals of the fracture risk by FRAX grasp it, and it is important to evaluate the fall risk. What an interval, a motor function including the lower limbs muscular strength evaluate in a fall risk evaluation and TUG and walking speed temporarily for a fall risk evaluation for, the eye opening single leg right time to leave is desirable. It is a problem that an evaluation and treatment for osteoporosis are insufficient by recent DPC induction...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912389/-osteoporosis-liaison-service-and-medication-instruction
#15
Fujiko Miyahara
The goals of the osteoporosis liaison service are to prevent the disease more effectively, to diagnose it properly and to provide a higher quality treatment for it as well as to increase healthy life- span and to minimize the gap in health status by offering raising awareness activities. Pharmacist can play an important role in achieving both of goals. "The family pharmacist system", which was introduced by the Pharmaceuticals and Medical Devices Law(Yakkiho)in 2016, is expected to contribute to achieve the former goal while "Health supporting pharmacy" is expected to strive for the latter goal...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912387/-osteoporosis-liaison-service-and-exercise-regimens-based-on-locomotive-syndrome
#16
Hideaki Ishibashi
The purpose of Osteoporosis Liaison Service(OLS)is primary and secondary prevention of osteoporosis and fragility fracture by multiple medical occupations. Exercise instruction and exercise intervention are important factors in OLS. Exercise has effects of increasing bone density and preventing falls. In OLS, it is also necessary to disseminate knowledge on osteoporosis and fractures to the public. Main measures against locomotive syndrome(LS), meaning weakening of ambulatory ability, are exercise and nutrition, and the LS prevention campaign is thought to lead to prevention of falls...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912386/-implementation-of-fracture-liaison-service-for-a-secondary-prevention-of-fragility-fracture
#17
Noriaki Yamamoto
Secondary fracture prevention in aged people is most important issue for the reduction of fragility fractures. Implemetation of fractuire liaison service play a key role to achieve secondary fracture prevention with continuous and comprehensive care for fracture patients. Fracture Liaison Service are spread in world-wide, and demonstrated the effects for fracture incidence and economical aspects.
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912385/-primary-fracture-prevention-through-the-osteoporosis-liaison-service
#18
Shinichi Nakatoh
It is difficult to prevent primary fragility fractures because the subjects have not yet experienced a fracture. The offers of the community Osteoporosis Liaison Service are important for primary prevention of fragility fractures. The prevention, education, enlightenment, and the offer of osteoporosis examinations are included in this service. It is necessary to deliver the prevention services and osteoporosis education according to the age of the subjects. Hence, for young people, it is effective to include in school education that getting high peak bone mass is important, and for the middle-aged population, it is necessary to include education on the maintenance of bone quantity and the impact on risk factors such as smoking and excessive alcohol consumption...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28912384/-fracture-liaison-service-and-osteoporosis-liaison-service
#19
Hiroshi Hagino
Fracture Liaison Service(FLS)was initiated in the late 1990s in Europe then afterwards spread to North America and Australia. The aim of FLS is to prevent secondary fractures after fragility fractures. Because of its usefulness it has become a global success through proof of its high efficacy and cost-effectiveness. The Japan Osteoporosis Society(JOS)initiated Osteoporosis Liaison Service(OLS)in Japan. FLS and OLS have the same aim-to prevent secondary fractures; however, OSL also aims to prevent primary fractures in clinics and the community...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28910889/-clinical-features-of-traumatic-optic-neuropathy-in-265-cases
#20
M Chen, Y Jiang, J F Wen, N Li, J Qiu, N K Zhang, J B Ju
Objective: To analyze the clinical features and the pathogenetic law of traumatic optic neuropathy through epidemiologic study. Methods: 265 cases (275 eyes) with TON treated in Department of Otorhinolaryngology Head and Neck Surgery, the Affiliated Hospital of Qingdao University from April 1999 to August 2015 were retrospectively analyzed. Multiple Logistic regression analyses were used to evaluate potential prognostic factors on visual acuity. Results: TON occured mostly in young (194/265, 73.21%) man (235/265, 88...
September 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
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