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https://www.readbyqxmd.com/read/28640764/the-efficacy-of-massage-in-reducing-nodule-formation-after-poly-l-lactic-acid-administration-for-facial-volume-loss-a-randomized-evaluator-blinded-clinical-trial-erratum
#1
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28640588/calcitonin-loaded-thermosensitive-hydrogel-for-long-term-anti-osteopenia-therapy
#2
Yanpeng Liu, Xiaobin Chen, Sheyu Li, Qiang Guo, Jing Xie, Lin Yu, Xinyuan Xu, Chunmei Ding, Jianshu Li, Jiandong Ding
Effective anti-osteopenia therapy can be achieved by designing long-term protein/peptide drug delivery systems for bone trabecula restoration. Here we show that a complex of salmon calcitonin and oxidized calcium alginate (sCT-OCA) was prepared and loaded into a thermosensitive copolymer hydrogel for long-term anti-osteopenia treatment. The triblock copolymer, poly(D,L-lactic acid-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(D,L-lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) exhibited sol-gel transition at body temperature...
June 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28640585/thermally-and-electrically-triggered-triple-shape-memory-behavior-of-poly-vinyl-acetate-poly-lactic-acid-due-to-graphene-induced-phase-separation
#3
Mohammad Sabzi, Masoud Babaahmadi, Mohammadreza Rahnama
This work aimed to develop a facile and broadly applicable method for fabricating a multi-stimuli responsive triple-shape memory polymer (SMP). Hence, herein the SMPs were prepared through the simple physical blending of two commercially available biopolymers, poly(lactic acid) (PLA) and poly(vinyl acetate) (PVAc), in the presence of robust and conductive graphene nanoplatelets. Interestingly, atomic force microscopy (AFM) observations and thermal analyses revealed that the presence of nanofillers led to phase separation and appearance of two well-separated transition temperatures in the blend of these two miscible polymers...
June 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28637158/a-reused-method-for-molasses-processed-wastewater-effect-on-silage-quality-and-anaerobic-digestion-performance-of-pennisetum-purpereum
#4
Lianhua Li, Zhenhong Yuan, Yongming Sun, Xiaoying Kong, Pengyu Dong, Jia Zhang
The silage quality and anaerobic digestion performance of Pennisetum purpereum with molasses-processed wastewater addition were assessed. The silage samples with molasses-processed wastewater addition obtained higher lactic acid concentration of 15.18-23.38mg/g FM, lower pH value of 3.96-4.45 and lower NH3-N content of 0.47-0.64mg/g FM. No obvious difference was observed in the dominant phyla and genus, but the relative abundance of Lactobacillus reached up to 77.39%, increased by 84% compared to the silage samples without molasses-processed wastewater addition...
May 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28636315/fabrication-of-hierarchical-macroporous-biocompatible-scaffolds-by-combining-pickering-high-internal-phase-emulsion-templates-with-three-dimensional-printing
#5
Ting Yang, Yang Hu, Chaoyang Wang, Bernard P Binks
Biocompatible and biodegradable porous scaffolds with adjustable pore structure have aroused increasing interest in bone tissue engineering. Here, we report a facile method to fabricate hierarchical macroporous biocompatible (HmPB) scaffolds by combining Pickering high internal phase emulsion (HIPE) templates with three-dimensional (3D) printing. HmPB scaffolds composed of a polymer matrix of poly(L-lactic acid), PLLA, and poly(ε-caprolactone), PCL, are readily fabricated by solvent evaporation of 3D printed Pickering HIPEs which are stabilized by hydrophobically modified silica nanoparticles (h-SiO2)...
June 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28635284/competing-stereocomplexation-and-homocrystallization-of-poly-l-lactic-acid-poly-d-lactic-acid-racemic-mixture-effects-of-miscible-blending-with-other-polymer
#6
Jianna Bao, Xiaojia Xue, Kai Li, Xiaohua Chang, Qing Xie, Chengtao Yu, Pengju Pan
Promoting the stereocomplexation ability of high-molecular-weight poly(L-lactic acid) (PLLA) and poly(D-lactic acid) (PDLA) is an efficient way to improve the thermal resistance of resulted materials. Herein, we studied the competing crystallization kinetics, polymorphic crystalline structure, and lamellae structure of PLLA/PDLA component in its miscible blends with poly(vinyl acetate) (PVAc) and proposed a method to improve the stereocomplexation ability of PLLA and PDLA through miscible blending with the other polymer...
June 21, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28634850/novel-vitamin-b12-producing-enterococcus-spp-and-preliminary-in-vitro-evaluation-of-probiotic-potentials
#7
Ping Li, Qing Gu, Yuejiao Wang, Yue Yu, Lanlan Yang, Jieyan V Chen
Vitamin B12 is an essential nutrient required for crucial metabolic processes in humans. Vitamin B12-producing lactic acid bacteria (LAB) have been attracting increased attentions currently because of the generally recognized as safe (GRAS) status. Most of recent studies focused on Lactobacillus, and little is known about B12-producing Enterococcus. In the present study, five Enterococcus strains isolated from infant feces were identified as vitamin B12 producers. Among them, Enterococcus faecium LZ86 had the highest B12 production (499...
June 20, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28634732/engineering-poly-lactic-co-glycolic-acid-plga-micro-and-nano-carriers-for-controlled-delivery-of-17%C3%AE-estradiol
#8
Alesia V Prakapenka, Heather A Bimonte-Nelson, Rachael W Sirianni
With menopause, circulating levels of 17β-estradiol (E2) markedly decrease. E2-based hormone therapy is prescribed to alleviate symptoms associated with menopause. E2 is also recognized for its beneficial effects in the central nervous system (CNS), such as enhanced cognitive function following abrupt hormonal loss associated with ovariectomy. For women with an intact uterus, an opposing progestogen component is required to decrease the risk of developing endometrial hyperplasia. While adding an opposing progestogen attenuates these detrimental effects on the uterus, it can attenuate the beneficial effects of E2 in the CNS...
June 20, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28633473/experimental-evolution-and-the-adjustment-of-metabolic-strategies-in-lactic-acid-bacteria
#9
Herwig Bachmann, Douwe Molenaar, Filipe Branco Dos Santos, Bas Teusink
Experimental evolution of microbes has gained lots of interest in recent years, mainly due to the ease of strain characterisation through next-generation sequencing. While evolutionary and systems biologists use experimental evolution to address fundamental questions in their respective fields, studies with lactic acid bacteria are often more directed by applied questions. Insight into population and genome dynamics are valuable for experimental design and data interpretation, and it is becoming increasingly apparent how different constraints limit and govern the outcome of microbial adaptation to a selective environment...
June 19, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28633051/influence-of-lactic-acid-and-post-treatment-recovery-time-on-the-heat-resistance-of-listeria-monocytogenes
#10
Yasuo Omori, Kiyotaka Miake, Hiromi Nakamura, Eriko Kage-Nakadai, Yoshikazu Nishikawa
The aim of this study was to evaluate the effect of lactic acid (LA) with and without organic material at various post-treatment recovery times on the heat resistance of Listeria monocytogenes (Lm). LA decreased Lm numbers; however, the effect was remarkably attenuated by the presence of organic matter. Five strains of Lm were treated with LA and the listericidal effects were compared. The effect of LA varied depending on the strain, with ≥3.0% (w/w) LA required to kill the Lm strains in a short time. The heat resistance of Lm treated with LA was examined with respect to the time interval between the acid treatment and the subsequent manufacturing step...
June 12, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28630857/effectiveness-of-a-commercial-lactic-acid-bacteria-intervention-applied-to-inhibit-shiga-toxin-producing-escherichia-coli-on-refrigerated-vacuum-aged-beef
#11
Katie R Kirsch, Tamra N Tolen, Jessica C Hudson, Alejandro Castillo, Davey Griffin, T Matthew Taylor
Because of their antagonistic activity towards pathogenic and spoilage bacteria, some members of the lactic acid bacteria (LAB) have been evaluated for use as food biopreservatives. The objectives of this study were to assess the antimicrobial utility of a commercial LAB intervention against O157 and non-O157 Shiga-toxigenic E. coli (STEC) on intact beef strip loins during refrigerated vacuum aging and determine intervention efficacy as a function of mode of intervention application. Prerigor strip loins were inoculated with a cocktail (8...
2017: International journal of food science
https://www.readbyqxmd.com/read/28630704/the-effects-of-a-post-exercise-carbohydrate-and-protein-supplement-on-repeat-performance-serum-chemistry-insulin-and-glucagon-in-competitive-weight-pulling-dogs
#12
Christopher W Frye, Gretchen M VanDeventer, Gina K Dinallo, Jennifer A Poplarski, Sabine Mann, Ella Pittman, Brian M Zanghi, Joseph J Wakshlag
The physiological demands of weight-pulling dogs have yet to be investigated. Two groups of competitive weight-pulling dogs both underwent two identical pull series 3 h apart. The control group (n 8) was compared with a group fed a rapidly digestible carbohydrate and protein supplement after the first pull series (n 9). Blood was drawn before and after each pull series as well as at 15 and 30 min after the first pull series finished. Biochemistry values remained unremarkable throughout the study in both groups regardless of supplementation or exercise over time...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28629998/aloe-emodin-ae-nanoparticles-suppresses-proliferation-and-induces-apoptosis-in-human-lung-squamous-carcinoma-via-ros-generation-in-vitro-and-in-vivo
#13
Yuan-Yuan Wu, Jing-Hua Zhang, Jing-Hua Gao, Yong-Sheng Li
Human lung squamous cell carcinoma is a deadly cancer for which present therapeutic strategies are inadequate. And traditional chemotherapy results in severe systemic toxicity. Compounds from living organisms often exert a biological activity, triggering several targets, which may be useful for the improvement of novel pharmaceuticals. Aloe-emodin (AE), a well-known natural compound, is a primary component of anthraquinones in Aloe vera and exhibits anti-proliferative and apoptotic effects on various tumor cells...
June 16, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28629804/zero-order-controlled-release-delivery-of-cholecalciferol-from-injectable-biodegradable-microsphere-in-vitro-characterization-and-in-vivo-pharmacokinetic-studies
#14
Lalit Vora, Sita V G, Pradeep Vavia
Poly(lactic-co-glycolic acid) microspheres loaded with cholecalciferol (CL), more bioactive form of vitamin D was developed as an injectable controlled drug release system and was evaluated for its feasibility of once a month delivery. The CL loaded microspheres (CL-MS) were prepared by simple oil in water (O/W) emulsion-solvent evaporation technique incorporated with a stabilizer, Tocopherol Succinate (TS). Different formulation as well as process parameters were investigated namely concentration of emulsifier, concentration of stabilizer and drug: polymer mass ratios...
June 16, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28629108/lactic-acid-production-from-sophora-flavescens-residues-pretreated-with-sodium-hydroxide-reutilization-of-the-pretreated-liquor-during-fermentation
#15
Juan Wang, Ming Gao, Jianguo Liu, Qunhui Wang, Cong Wang, Zihe Yin, Chuanfu Wu
The feasibility of lactic acid production from Sophora flavescens residues (SFRs) pretreated with sodium hydroxide with the reutilization of the pretreated liquor during fermentation was investigated. After sodium hydroxide pretreatment, 67.5% of the lignin was removed, and hydrolysis efficiency increased from 37.3% to 79.2%. The reutilization of pretreated liquor at 50% loading during open fermentation of unwashed SFR increased lactic acid production by 34.1%. The pretreated liquor acted as pH buffer and resulted in stable pH and high cellulase activity during fermentation...
June 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28629062/construction-of-poly-lactic-co-glycolic-acid-zno-nanorods-ag-nanoparticles-hybrid-coating-on-ti-implants-for-enhanced-antibacterial-activity-and-biocompatibility
#16
Yiming Xiang, Jun Li, Xiangmei Liu, Zhenduo Cui, Xianjin Yang, K W K Yeung, Haobo Pan, Shuilin Wu
Poly(lactic-co-glycolic acid)/Ag/ZnO nanorods coating were successfully prepared on the surface of Ti metallic implants using a hydrothermal method and subsequent spin-coating of mixtures of poly(lactic-co-glycolic acid) and silver nanoparticles. The poly(lactic-co-glycolic acid)/Ag/ZnO nanorods coating exhibited excellent antibacterial efficacy of over 96% against both Staphylococcus aureus and Escherichia coli when the initial content of Ag nanoparticles was over 3wt%. In addition, the release of both silver and zinc could last for over a hundred days due to the enwrapping of poly(lactic-co-glycolic acid)...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28629015/poly-n-isopropylacrylamide-poly-l-lactic-acid-co-%C3%A9-caprolactone-fibers-loaded-with-ciprofloxacin-as-wound-dressing-materials
#17
Heyu Li, Gareth R Williams, Junzi Wu, Haijun Wang, Xiaozhu Sun, Li-Min Zhu
In this work, we aimed to develop new materials to reduce the secondary injuries which can be imparted when replacing wound dressings. Electrospun fibers based on the thermoresponsive polymer poly(N-isopropylacrylamide) (PNIPAAm), poly(l-lactic acid-co-ɛ-caprolactone) (PLCL), and the antibiotic ciprofloxacin (CIF) were prepared. The water contact angle of fibers made from a blend of PNIPAAm and PLCL changed dramatically when the temperature was increased above 32°C. Sustained release of CIF from the formulations was observed over >200h...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28629009/surgical-suture-braided-with-a-diclofenac-loaded-strand-of-poly-lactic-co-glycolic-acid-for-local-sustained-pain-mitigation
#18
Beom Kang Huh, Byung Hwi Kim, Se-Na Kim, Chun Gwon Park, Seung Ho Lee, Ka Ryeong Kim, Chan Yeong Heo, Young Bin Choy
In this work, we propose a surgical suture that can sustainably release diclofenac (DF) for the local pain relief of surgical wounds. We separately fabricated a DF-loaded strand composed of a biodegradable polymer, poly(lactic-co-glycolic acid) (PLGA), which was then braided with a surgical suture already in clinical use, i.e., VICRYL™. In this way, the drug-delivery suture presented herein could release DF in a sustained manner for 10days while maintaining the mechanical strength needed for wound closure...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28628686/off-face-usage-of-poly-l-lactic-acid-for-body-rejuvenation
#19
Ahmad Jabbar, Suleima Arruda, Neil Sadick
<p>Injectable soft-tissue augmentation agents have become popular alternatives to surgical procedures for the aging face and body. In contrast to temporary, space-occupying replacement fillers such as collagen-based and hyaluronic acid products, poly-l-lactic acid (PLLA) has been demonstrated to gradually promotes deposition of collagen via a biostimulatory response, with therapeutic effects lasting approximately two years. In 2004, the FDA approved its use for rejuvenation of facial contours secondary to lipoatrophy associated with antiretroviral therapy for HIV infection...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28627673/release-characteristics-of-bone%C3%A2-like-hydroxyapatite-poly-amino-acid-loaded-with-rifapentine-microspheres-in%C3%A2-vivo
#20
Yuwu Liu, Jiming Zhu, Dianming Jiang
Bone-like hydroxyapatite/poly amino acid (BHA/PAA) is a potential bone repair material. Rifapentine-loaded poly(lactic‑co‑glycolic acid) microspheres (RPMs) are bioactive and efficient controlled‑release delivery systems used in vitro. The aim of the present study was to investigate the in vivo drug release characteristics of RPM‑loaded BHA/PAA on a rabbit model of bone defect. RPM was combined with BHA/PAA to obtain the drug‑loaded, slow‑releasing bioactive material. Bone defects were generated in New Zealand white rabbits and the rabbits were then implanted with RPM‑loaded BHA/PAA...
June 9, 2017: Molecular Medicine Reports
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