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https://www.readbyqxmd.com/read/28821541/targeting-mir-423-5p-reverses-exercise-training-induced-hcn4-channel-remodeling-and-sinus-bradycardia
#1
Alicia D'Souza, Charles M Pearman, Yanwen Wang, Shu Nakao, Sunil Jit R Logantha, Charlotte Cox, Hayley J Bennett, Yu Zhang, Anne Berit Johnsen, Nora Linscheid, Pi C Poulsen, Jonathan Elliott, Jessica Coulson, Jamie S McPhee, Abigail C Robertson, Paula A da Costa Martins, Ashraf Kitmitto, Ulrik Wisloff, Elizabeth J Cartwright, Oliver Monfredi, Alicia Lundby, Halina Dobrzynski, Delvac Oceandy, Gwilym M Morris, Mark R Boyett
Rationale: Downregulation of the pacemaking ion channel, HCN4, and the corresponding ionic current, If, underlies exercise training-induced sinus bradycardia in rodents. If this occurs in humans, it could explain the increased incidence of bradyarrhythmias in veteran athletes and it will be important to understand the underlying processes. Objective: To test the role of HCN4 in the training-induced bradycardia in human athletes and investigate the role of micro-RNAs (miRs) in the repression of HCN4. Methods and Results: As in rodents, the intrinsic heart rate was significantly lower in human athletes than non-athletes and in all subjects the rate-lowering effect of the HCN selective blocker, ivabradine, was significantly correlated with the intrinsic heart rate, consistent with HCN repression in athletes...
August 17, 2017: Circulation Research
https://www.readbyqxmd.com/read/28817510/elite-distance-runners-a-45-year-follow-up
#2
Sarah Everman, James W Farris, R Curtis Bay, Jack T Daniels
PURPOSE: The present longitudinal study assessed cardiorespiratory capacity and running economy of Olympic athletes over several decades to measure changes in fitness in an elite group during aging. METHODS: Twenty-six male runners training for the 1968 Olympics were recruited. Heart rate, VO2max, ventilation, and running economy were measured in 1968, 1993, and 2013. In 2013, 22 of the original runners participated: three passed away between 1993 and 2013, and one declined to participate...
August 16, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28813341/coaching-effectiveness-the-coach-athlete-relationship-at-its-heart
#3
REVIEW
Sophia Jowett
Coaching has been often viewed as a context within which coaches operate to largely bring about changes in athlete's performance and wellbeing. One key factor to successful outcomes in coaching is the quality of the relationship between coaches and athletes. In this article, I propose that the coach-athlete relationship is at the heart of coaching. Moreover, the aim is to describe and explain how the quality of the relationship coaches and athletes develop and maintain over the course of their sporting partnership alongside coaches and athletes' knowledge and outcomes, form a system that is capable of defining coaching effectiveness and success...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28810170/the-role-of-speed-and-incline-in-the-spontaneous-choice-of-technique-in-classical-roller-skiing
#4
Gertjan Ettema, Espen Kveli, Magne Øksnes, Øyvind Sandbakk
Cross-country skiers change technique depending on terrain (incline) and effort (work rate; speed at a particular incline or resistance). The literature is not unequivocal about the influence of incline or speed on the choice of technique, i.e., which of these act as a 'control parameter'. Identifying task related control parameters for spontaneous technique shifts assists elucidating which mechanisms are active for triggering technique transitions. The aim of this study was to investigate whether speed or incline acted as such control parameter for technique shifts during classic style roller skiing...
August 12, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28798200/wearable-physiological-monitoring-for-human-thermal-work-strain-optimization
#5
Mark J Buller, Alexander Pearson Welles, Karl E Friedl
Safe performance limits of soldiers and athletes have typically relied on predictive work-rest models of ambient conditions, average work intensity, and characteristics of the population. Bioengineering advances in noninvasive sensor technologies including miniaturization, reduced cost, power requirements, and comfort now make it possible to produce individual predictions of safe thermal-work limits. These precision medicine assessments depend on the development of thoughtful algorithms based on physics and physiology...
August 10, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28796126/physiological-pattern-changes-in-response-to-a-simulated-competition-in-elite-women-artistic-gymnasts
#6
Laurie Isacco, Gaël Ennequin, Johan Cassirame, Nicolas Tordi
The outstanding progress in women's artistic gymnastics in recent decades has led to increased technical and physiological demands. The aim of this study was to investigate i) the physiological demands of elite French gymnasts and ii) the impact of a competitive routine on physiological pattern changes. Fourteen French elite female gymnasts performed anthropometric measurements, physical fitness tests and a simulated four event competition. Heart rate (HR) was continuously recorded throughout the duration of the simulated competition...
August 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28795011/cardiac-screening-to-prevent-sudden-death-in-young-athletes
#7
REVIEW
Christopher Schmehil, Devika Malhotra, Dilip R Patel
Sudden cardiac death (SCD) is a sudden and unexpected death caused by loss of heart of function. SCD may occur in any population, but when it occurs on the playing field in a young individual, communities worldwide are affected. Although these events are rare, media coverage of sudden cardiac arrests in young athletes have created the impression that these events are far more common than they appear. With a heightened awareness of SCD in young athletes, screening methods have been developed to try and prevent these events from occurring...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28790928/enhanced-right-chamber-remodeling-in-endurance-ultra-trail-athletes-compared-to-marathon-runners-detected-by-standard-and-speckle-tracking-echocardiography
#8
Kristian Ujka, Luca Bastiani, Gennaro D'Angelo, Bruna Catuzzo, Alessandro Tonacci, Simona Mrakic-Sposta, Alessandra Vezzoli, Guido Giardini, Lorenza Pratali
Background: Strenuous and endurance exercise training have been associated with morphological and functional heart remodeling. Two-dimensional speckle-tracking echocardiography (STE) is a novel technique that allows an accurate quantification of global myocardium deformation. Our aim was to evaluate together left and right cardiac remodeling in different long-distance running athletes: marathon runners (42 km) (M) and endurance mountain runners (>300 Km) (UT). Methods: A total of 92 athletes (70 males, 76%) including 47 M [age 45 ± 7 years; training: 18 (9-53) years(*)days/week], 45 UT [age 42 ± 9, training: 30 (15-66) years(*)days/week] underwent conventional echocardiography and STE (Beyond Diogenes 2...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28772335/qtc-interval-in-adolescents-and-young-athletes-influence-of-correction-formulas
#9
Salvatore Francesco Gervasi, Massimiliano Bianco, Vincenzo Palmieri, Francesco Cuccaro, Paolo Zeppilli
A QTc interval at the upper limits in young athletes can be challenging. Regardless of factors able to influence it (age, electrolytes, etc.), several authors underlined that rate correction formulas can often underestimate/overestimate it. Our objective was to identify the most reliable formula and relative upper normal limit of QTc for this population. The rest ECG of 701 healthy elite male athletes was analyzed. QTc was calculated with 4 formulas (Bazett, Fridericia, Framingham, Hodges). Correlation/regression analysis of QTc vs...
August 3, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28767469/marijuana-and-its-effects-on-athletic-performance-a-systematic-review
#10
Kien V Trinh, Dion Diep, Hannah Robson
OBJECTIVE: To determine the effects of marijuana on athletic performance. DESIGN: We searched MEDLINE, EMBASE, CINAHL, PsycINFO, AMED, and SPORTDiscus from their beginning to September 2016. Study quality was assessed using the Cochrane collaboration tool for assessing risk of bias and the Cochrane GRADE scale. No meta-analyses were performed for this review. SETTING: Subjects in a track, gym, or recreational ward. PARTICIPANTS: Any primary study which included male and female adults of any athletic background between ages 18 and 65, with no other comorbid conditions...
July 27, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28759538/validity-and-reliability-of-the-hexoskin%C3%A2-wearable-biometric-vest-during-maximal-aerobic-power-testing-in-elite-cyclists
#11
Catherine A Elliot, Michael J Hamlin, Catherine A Lizamore
The purpose of this study was to investigate the validity and reliability of the Hexoskin® vest for measuring respiration and heart rate (HR) in elite cyclists during a progressive test to exhaustion. Ten male elite cyclists (age 28.8 ± 12.5 yr, height 179.3 ± 6.0 cm, weight 73.2 ± 9.1 kg, V˙ O2max 60.7 ± 7.8 ml.kg.min mean ± SD) conducted a maximal aerobic cycle ergometer test using a ramped protocol (starting at 100W with 25W increments each min to failure) during two separate occasions over a 3-4 day period...
July 28, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28759533/physiological-responses-to-and-athlete-and-coach-perceptions-of-exertion-during-small-sided-basketball-games
#12
A Vaquera, D Suárez-Iglesias, X Guiu, R Barroso, G Thomas, A Renfree
This study describes heart rate (HR) responses during different small sided games (SSGs) in junior basketball players, and identifies the level of agreement between athlete and coach perceptions of internal training load calculated using the in-task rating of perceived exertion (RPE) method. Over a 6 week period, 12 male junior basketball players who played in the Spanish national under-18 League, played 7 games of one-a-side (1v1), 6 games of two-a-side (2v2), 8 games of five-a-side (5v5), and 5 games of superiority (3v2) situations...
July 28, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28756079/-exercise-testing-new-guidelines
#13
Dany Michel Marcadet
The GERS (Exercise Rehabilitation and Sports Group of the French Society of Cardiology) has decided to update current guidelines regarding the practice of EKG stress tests. Since the last update dates from 1997, the GERS judged it necessary to integrate data from new works and advancements made in the last 20 years. Good clinical practices and safety conditions are better defined regarding the structure, location, material, staff competency, as well as convention with hospital structures. The diagnosis of coronary artery disease remains the principal indication for a stress test...
July 26, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28748371/acute-effects-of-heated-resistance-exercise-in-female-and-male-power-athletes
#14
Julia R Casadio, Adam G Storey, Fabrice Merien, Andrew E Kilding, James D Cotter, Paul B Laursen
PURPOSE: To determine the effects of heated resistance exercise on thermal strain, neuromuscular function and hormonal responses in power athletes. METHODS: Sixteen (n = 8 female; 8 male) highly trained power athletes completed a combined strength and power resistance exercise session in hot (HOT ~30 °C) and temperate (CON ~20 °C) conditions. Human growth hormone (hGH), cortisol and testosterone concentrations in plasma, peak power (counter-movement jump, CMJ) and peak force (isometric mid-thigh pull) were measured before and after each training session; thermoregulatory responses were monitored during training...
July 26, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28745470/effects-of-taurine-on-markers-of-muscle-damage-inflammatory-response-and-physical-performance-in-triathletes
#15
Bryan S Martinez Galan, Flavia Giolo de Carvalho, Priscila Carvalho Santos, Ronaldo Bucken Gobbi, Carlos Kalva-Filho, Marcelo Papoti, Adelino Sanchez Silva, Ellen C Freitas
BACKGROUND: The practice of prolonged exercise with high intensity, as seen in triathlon training, can cause physiological imbalances that might result in muscle fatigue, muscle damage and changes in systemic inflammatory response, thus reduce the athletes physical performance, therefore, both adequate total caloric and macronutrient intake also the use of a specific ergogenic aid, as taurine supplementation would be an alternative to prevent inflammation and muscle damage. In order to verify the effects of 8 weeks of taurine and chocolate milk supplementation, markers of muscle damage, inflammation, and aerobic capacity were quantified in triathletes...
July 25, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28744226/the-mucosal-immune-function-is-not-compromised-during-a-period-of-high-intensity-interval-training-is-it-time-to-reconsider-an-old-assumption
#16
Dennis-Peter Born, Christoph Zinner, Billy Sperlich
Purpose: The aim of the study was to evaluate the mucosal immune function and circadian variation of salivary cortisol, Immunoglobin-A (sIgA) secretion rate and mood during a period of high-intensity interval training (HIIT) compared to long-slow distance training (LSD). Methods: Recreational male runners (n = 28) completed nine sessions of either HIIT or LSD within 3 weeks. The HIIT involved 4 × 4 min of running at 90-95% of maximum heart rate interspersed with 3 min of active recovery while the LSD comprised of continuous running at 70-75% of maximum heart rate for 60-80 min...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28737589/validity-of-a-taekwondo-specific-test-to-measure-vo2peak-and-the-heart-rate-deflection-point
#17
Jader Sant'Ana, Emerson Franchini, Juan Murias, Fernando Diefenthaeler
This study investigated whether the progressive specific taekwondo test (PSTT) is a valid test to measure peak oxygen consumption (VO2PEAK) and the heart rate deflection point (HRDP) in taekwondo athletes. Eighteen male black belt athletes (25.3 ± 4.8 years; 8.2 ± 4.7 years of practice; 171.8 ± 4.7 cm; 76.1 ± 8.2 kg, and 13.1 ± 2.9% body fat) involved in regional and national level competitions performed the PSTT and an incremental treadmill test (IT). The following variables were analyzed: VO2PEAK, respiratory quotient, oxygen consumption at the HRDP (VO2HRDP), peak heart rate (HRPEAK), HRDP, and peak post-test blood lactate concentration...
July 19, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28730870/cardiac-autonomic-recovery-after-strength-exercise-in-lower-and-upper-limbs
#18
Naerton José Xavier Isidoro, Milana Drumond Ramos Santana, Vitor E Valenti, David M Garner, Luiz Carlos de Abreu
Introduction Strength exercises influence the cardiovascular system by promoting autonomic adjustments induced by the increased metabolic demand and consequent increase in local blood flow. However, it is unclear whether there are differences between upper and lower limbs. We aimedto evaluate recovery of cardiac autonomic modulation afterstrengthexercise in upper and lower limbs. Methods We analysed 29 healthy male subjects physically active but not professional athletes aged between 20 and 35 years old...
July 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28724040/cardiac-remodeling-indicators-in-adolescent-athletes
#19
Joaquim Castanheira, João Valente-Dos-Santos, Daniela Costa, Diogo Martinho, Jorge Fernandes, João Duarte, Nuno Sousa, Vasco Vaz, Luis Rama, António Figueiredo, Manuel Coelho-E-Silva
Objective: The idea that different sports and physical training type results in different cardiac adaptations has been widely accepted. However, this remodelling process among different sport modalities is still not fully understood. Thus, the current study aims to investigate the heart morphology variation associated with a set of different modalities characterized by distinct models of preparation and different methods and demands of training and completion. Method: The sample comprises 42 basketball players, 73 roller hockey players, 28 judo athletes and 21 swimmers...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28717602/expression-of-various-sarcomeric-tropomyosin-isoforms-in-equine-striated-muscles
#20
Syamalima Dube, Henry Chionuma, Amr Matoq, Ruham Alshiekh-Nasany, Lynn Abbott, Bernard J Poiesz, Dipak K Dube
In order to better understand the training and athletic activity of horses, we must have complete understanding of the isoform diversity of various myofibrillar protein genes like tropomyosin. Tropomyosin (TPM), a coiled-coil dimeric protein, is a component of thin filament in striated muscles. In mammals, four TPM genes (TPM1, TPM2, TPM3, and TPM4) generate a multitude of TPM isoforms via alternate splicing and/or using different promoters. Unfortunately, our knowledge of TPM isoform diversity in the horse is very limited...
2017: Open veterinary journal
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