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https://www.readbyqxmd.com/read/28719903/thinning-of-inner-retinal-layers-after-vitrectomy-with-silicone-oil-versus-gas-endotamponade-in-eyes-with-macula-off-retinal-detachment
#1
Konstantine Purtskhvanidze, Jost Hillenkamp, Jan Tode, Olaf Junge, Jürgen Hedderich, Johann Roider, Felix Treumer
PURPOSE: To evaluate retinal layer thickness with optical coherence tomography (OCT) in eyes with macula-off retinal detachment after silicone oil (SiO) or gas endotamponade. PROCEDURES: Cross-sectional study of 40 eyes with macula-off rhegmatogenous retinal detachment that underwent vitrectomy. 20 eyes received SiO tamponade and 20 matched eyes received gas. 33 healthy fellow eyes served as controls. Macular spectral domain OCT was performed with automated layer detection in the 5 inner subfields of the Early Treatment Diabetic Retinopathy Study (ETDRS) map...
July 19, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28715581/incidence-and-factors-influencing-retinal-displacement-in-eyes-treated-for-rhegmatogenous-retinal-detachment-with-vitrectomy-and-gas-or-silicone-oil
#2
Roberto dell'Omo, Andrea Scupola, Davide Viggiano, Maria Grazia Sammarco, Serena De Turris, Mario R Romano, Gabriela Grimaldi, Ermanno dell'Omo, Ciro Costagliola
Purpose: The purpose of this study was to study the incidence and factors influencing retinal displacement in eyes treated for rhegmatogenous retinal detachment (RRD) with pars plana vitrectomy (PPV) and gas or silicone oil. Methods: This was a prospective observational case series. One hundred twenty-five eyes with macula-off RRD from 125 patients underwent 25-gauge PPV at two vitreoretinal institutional practices. Eyes without proliferative vitreoretinopathy (PVR) or PVR grade A were tamponated with sulfur hexafluoride (SF6) gas, whereas eyes with PVR grade B received 1000 centistokes silicone oil (SO)...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28715396/smartphone-fundus-photography
#3
Hossein Nazari Khanamiri, Austin Nakatsuka, Jaafar El-Annan
Smartphone fundus photography is a simple technique to obtain ocular fundus pictures using a smartphone camera and a conventional handheld indirect ophthalmoscopy lens. This technique is indispensable when picture documentation of optic nerve, retina, and retinal vessels is necessary but a fundus camera is not available. The main advantage of this technique is the widespread availability of smartphones that allows documentation of macula and optic nerve changes in many settings that was not previously possible...
July 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28713647/evaluation-of-two-systems-for-fundus-controlled-scotopic-and-mesopic-perimetry-in-eye-with-age-related-macular-degeneration
#4
Julia S Steinberg, Marlene Saßmannshausen, Maximilian Pfau, Monika Fleckenstein, Robert P Finger, Frank G Holz, Steffen Schmitz-Valckenberg
PURPOSE: The purpose of this study was to evaluate and compare the MP-1S (Nidek Technologies, Padova, Italy) and the S-MAIA (CenterVue, Padova, Italy) for mesopic and scotopic fundus-controlled perimetry (FCP) in age-related macular degeneration (AMD). METHODS: Eleven eyes from 11 patients underwent mesopic and, after 30 minutes of dark adaptation, scotopic (MP-1S: Goldmann V, 200 ms, background luminance 0.0032 cd/m(2); S-MAIA: Goldman III, 200 ms, background luminance <0...
July 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28706282/retinal-degeneration-in-progressive-supranuclear-palsy-measured-by-optical-coherence-tomography-and-scanning-laser-polarimetry
#5
Birthe Stemplewitz, Robert Kromer, Eik Vettorazzi, Ute Hidding, Andreas Frings, Carsten Buhmann
This cross-sectional study compared the retinal morphology between patients with progressive supranuclear palsy (PSP) and healthy controls. (The retinal nerve fiber layer (RNFL) around the optic disc and the retina in the macular area of 22 PSP patients and 151 controls were investigated by spectral domain optical coherence tomography (SD-OCT). Additionally, the RNFL and the nerve fiber index (NFI) were measured by scanning laser polarimetry (SLP). Results of RNFL measurements with SD-OCT and SLP were compared to assess diagnostic discriminatory power...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28700128/assessment-of-trans-scleral-iontophoresis-delivery-of-lutein-to-the-human-retina
#6
Marco Lombardo, Valentina Villari, Norberto Micali, Pierre Roy, Sara Homem Sousa, Giuseppe Lombardo
The efficacy of novel scleral iontophoresis device for in-situ delivery of lutein to the human retina was assessed by resonance Raman spectroscopy technique. Eight human donor eye globes were used for experiments, six of which underwent trans-scleral iontophoresis delivery of lutein and the others two were used as controls. The scleral iontophoresis applicator was filled with liposome-enriched 0.1% lutein solution and the generator's current was set at 2.5 mA and delivered for 4 minutes. A custom resonance Raman spectroscopy (RRS) set-up was used for detecting lutein in the inner sclera, choroid, retinal periphery and macula of treated samples and controls...
July 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28695165/neonatal-retinoblastoma
#7
REVIEW
Tero T Kivelä, Theodora Hadjistilianou
From 7% to 10% of all retinoblastomas and from 44% to 71% of familial retinoblastomas in developed countries are diagnosed in the neonatal period, usually through pre- or post-natal screening prompted by a positive family history and sometimes serendipitously during screening for retinopathy of prematurity or other reasons. In developing countries, neonatal diagnosis of retinoblastoma has been less common. Neonatal retinoblastoma generally develops from a germline mutation of RB1, the retinoblastoma gene, even when the family history is negative and is thus usually hereditary...
July 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28693018/el-efecto-de-la-panfotocoagulaci%C3%A3-n-con-l%C3%A3-ser-en-edema-macular-diab%C3%A3-tico-con-el-fotocoagulador-pascal%C3%A2-versus-el-l%C3%A3-ser-de-arg%C3%A3-n-convencional
#8
Mohamed M Mahgoub, Tamer A Macky
Objetivo: El objetivo de este estudio fue comparar el efecto de la panfotocoagulación (PFC) en el edema macular diabético (EMD) en pacientes con retinopatía diabética proliferativa (RDP) con el fotocoagulador Pascal® (FP) vs. un fotocoagulador con láser de argón convencional (FLAC). Métodos: Se aleatorizó el uso de FP o FLAC en ochenta ojos con RDP y EMD con afectación central de la mácula. Ambos grupos tuvieron una evaluación de base de mejor agudeza visual corregida y fueron examinados con tomografía de coherencia óptica y angiografía con fluoresceína...
July 11, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28690534/a-case-of-rhegmatogenous-retinal-detachment-at-late-stage-following-endogenous-bacterial-endophthalmitis
#9
Daisaku Kimura, Takaki Sato, Hiroyuki Suzuki, Ryohsuke Kohmoto, Masanori Fukumoto, Kensuke Tajiri, Takatoshi Kobayashi, Teruyo Kida, Tsunehiko Ikeda
PURPOSE: To report a case of rhegmatogenous retinal detachment in the late stage, despite the fact that it had previously been halted after intravitreal injection of an antimicrobial agent against endogenous bacterial endophthalmitis (EBE). CASE: This study involved a 62-year-old male who had previously been diagnosed with septicemia due to liver abscess and the detection of Klebsiella pneumoniae in a culture of his liver abscess, and who underwent ophthalmic examination after his conjunctival hyperemia had failed to improve...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28689222/insights-into-autofluorescence-patterns-in-stargardt-macular-dystrophy-using-ultra-wide-field-imaging
#10
Vinod Kumar
PURPOSE: To characterize autofluorescence (AF) patterns occurring in Stargardt macular dystrophy (STGD1) using ultra-wide-field (UWF) imaging. METHODS: This paper is a cross-sectional observational study of 22 eyes of 11 patients (mean age 23.44 years) with Stargardt disease-fundus flavimaculatus who presented with decrease of vision at a tertiary eye care center. UWF short-wave AF images were obtained from all the patients using an Optos TX200 instrument. The main outcome measures were to assess patterns of AF changes seen on UWF AF imaging...
July 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28682018/vascular-displacement-in-idiopathic-macular-hole-after-single-layered-inverted-internal-limiting-membrane-flap-surgery
#11
Jae Jung Lee, In Ho Lee, Keun Heung Park, Kang Yeun Pak, Sung Who Park, Ik Soo Byon, Ji Eun Lee
PURPOSE: To compare vascular displacement in the macula after surgical closure of idiopathic macular hole (MH) after single-layered inverted internal limiting membrane (ILM) flap technique and conventional ILM removal. METHODS: This retrospective study included patients who underwent either vitrectomy and ILM removal only or vitrectomy with single-layered inverted ILM flap for idiopathic MH larger than 400 μm from 2012 to 2015. A customized program compared the positions of the retinal vessels in the macula between preoperative and postoperative photographs...
June 26, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28677725/two-heterozygous-mutations-identified-in-one-chinese-patient-with-bilateral-macular-coloboma
#12
Tao Li, Ying Lin, Hongbin Gao, Chuan Chen, Yi Zhu, Bingqian Liu, Yu Lian, Yonghao Li, Wenli Zhou, Hongye Jiang, Haichun Li, Qingxiu Wu, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu
Congenital macular coloboma is characterized by defined punched out atrophic lesions of the macula. The present study aimed to investigate the genetic alterations of one Chinese sporadic patient with bilateral large macular coloboma. Complete ophthalmic examinations, including best‑corrected visual acuity, slit‑lamp examination, fundus examination, fundus photograph and fundus fluorescein angiography imaging, Pentacam, and optical coherence tomography were performed on the patient. Genomic DNA was extracted from leukocytes in a peripheral blood sample collected from the patient, the patient's unaffected family members and from 200 unrelated control subjects from the same population...
June 29, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28677374/retinal-ganglion-cell-inner-plexiform-layer-thickness-in-patients-with-parkinson-s-disease
#13
Maja Živković, Volkan Dayanir, Jelena Stamenović, Srdjan Ljubisavljević, Ana Pražić, Marko Zlatanović, Gordana Zlatanović, Vesna Jakšić, Marija Radenković, Svetlana Jovanović
<i><b>Introduction: </b> The aim of the paper was to analyze the changes in the macular ganglion cell layer and inner plexiform layer (GCL-IPL) thickness in patients with Parkinson's disease. <b>Material and methods</b>: The study enrolled 46 patients with established diagnosis of Parkinson's disease and 46 healthy subjects. Both groups were age- and gender-matched. An OCT protocol, namely standardized Ganglion Cell Analysis algorithm was used to measure the thickness of the macular GCL-IPL layer...
2017: Folia Neuropathologica
https://www.readbyqxmd.com/read/28676993/crystalline-retinopathy-association-with-flupentixol-intake
#14
Pradeep Kumar, Raghav Ravani, Prateek Kakkar, Anu Sharma, Atul Kumar
AIM: To report the first case report of an association between flupentixol and crystalline retinopathy. STUDY DESIGN: Observational, Case report. CASE REPORT: We report a case of crystalline retinopathy in a 36-year-old female who was suffering from depression and being treated with tablet flupentixol in a cumulative dose of 4380 mg over two years. Fundus examination of both eyes showed multiple, discrete, yellowish white refractile intraretinal deposits over the macula and peripapillary region, located in the inner retina as shown by OCT...
July 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28676279/projection-resolved-optical-coherence-tomography-angiography-of-macular-retinal-circulation-in-glaucoma
#15
Hana L Takusagawa, Liang Liu, Kelly N Ma, Yali Jia, Simon S Gao, Miao Zhang, Beth Edmunds, Mansi Parikh, Shandiz Tehrani, John C Morrison, David Huang
PURPOSE: To detect macular perfusion defects in glaucoma using projection-resolved optical coherence tomography (OCT) angiography. DESIGN: Prospective observation study. PARTICIPANTS: A total of 30 perimetric glaucoma and 30 age-matched normal participants were included. METHODS: One eye of each participant was imaged using 6 × 6-mm macular OCT angiography (OCTA) scan pattern by 70-kHz 840-nm spectral-domain OCT. Flow signal was calculated by the split-spectrum amplitude-decorrelation angiography algorithm...
July 1, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28671896/evaluation-of-macular-ischemia-in-eyes-with-central-retinal-vein-occlusion-an-optical-coherence-tomography-angiography-study
#16
Rima Ghashut, Yuki Muraoka, Sotaro Ooto, Yuto Iida, Yuko Miwa, Kiyoshi Suzuma, Tomoaki Murakami, Shin Kadomoto, Akitaka Tsujikawa, Nagahisa Yoshimura
PURPOSE: To quantitatively assess macular perfusion status using optical coherence tomography angiography in eyes with aflibercept-treated central retinal vein occlusion and resolved macular edema and to investigate the impact of macular morphology and perfusion status on visual function. METHODS: This prospective consecutive case series included 23 patients with central retinal vein occlusion. All patients received intravitreal aflibercept injections before analysis...
June 30, 2017: Retina
https://www.readbyqxmd.com/read/28669781/prevalence-of-diabetic-retinopathy-and-blindness-in-indonesian-adults-with-type-2-diabetes
#17
Muhammad Bayu Sasongko, Felicia Widyaputri, Angela Nurini Agni, Firman Setya Wardhana, Satyaprabha Kotha, Prateek Gupta, Tri Wahyu Widayanti, Supanji Haryanto, Rifa Widyaningrum, Tien Yin Wong, Ryo Kawasaki, Jie Jin Wang
PURPOSE: To report the prevalence of diabetic retinopathy (DR) and DR-related blindness in Indonesian population with type 2 diabetes. DESIGN: Population-based cross-sectional study. SETTING: Community health centers. STUDY POPULATION: We recruited 1184 people aged older than 30 years with type 2 diabetes residing in Jogjakarta, Indonesia. Multi-stage, clustered random sampling based on regencies and districts in Jogjakarta was used...
June 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28669779/combined-hamartoma-of-the-retina-and-retinal-pigment-epithelium-an-optical-coherence-tomography-based-reappraisal
#18
Rohan Chawla, Vinod Kumar, Koushik Tripathy, Atul Kumar, Pradeep Venkatesh, Farin Rajmohmad Shaikh, Rajpal Vohra, Kabiruddin Molla, Saurabh Verma
PURPOSE: To analyze the optical coherence tomography (OCT) characteristics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving the macula. DESIGN: Retrospective, observational case series. METHODS: Setting: Single institutional. STUDY POPULATION: Fourteen consecutive patients of CHRRPE were included. OBSERVATION PROCEDURES: The authors analyzed the clinical features, color fundus photography, and swept source or spectral domain OCT of all the involved eyes...
June 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28669776/association-of-vascular-vs-avascular-subretinal-hyperreflective-material-with-aflibercept-response-in-age-related-macular-degeneration
#19
Yu Kawashima, Masayuki Hata, Akio Oishi, Sotaro Ooto, Kenji Yamashiro, Hiroshi Tamura, Manabu Miyata, Akihito Uji, Naoko Ueda-Arakawa, Akitaka Tsujikawa
PURPOSE: To investigate flow signal within subretinal hyperreflective material (SHRM) using optical coherence tomography angiography (OCTA) and its association with aflibercept treatment responses in treatment-naïve neovascular age-related macular degeneration (nAMD). DESIGN: Prospective consecutive interventional case series METHODS: Forty-four eyes of 44 patients with treatment-naive nAMD manifesting SHRM on OCT were studied. All patients underwent OCTA and received three monthly aflibercept injections...
June 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28668316/ontogenetic-development-of-the-inner-ear-saccule-and-utricle-in-the-lusitanian-toadfish-potential-implications-for-auditory-sensitivity
#20
Patrícia P Chaves, Ciara M C Valdoria, M Clara P Amorim, Raquel O Vasconcelos
Studies addressing structure-function relationships of the fish auditory system during development are sparse compared to other taxa. The Batrachoididae has become an important group to investigate mechanisms of auditory plasticity and evolution of auditory-vocal systems. A recent study reported ontogenetic improvements in the inner ear saccule sensitivity of the Lusitanian toadfish, Halobatrachus didactylus, but whether this results from changes in the sensory morphology remains unknown. We investigated how the macula and organization of auditory receptors in the saccule and utricle change during growth in this species...
June 15, 2017: Hearing Research
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