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Peptic ulcer disease

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https://www.readbyqxmd.com/read/29340282/should-vasoconstrictors-be-considered-in-a-cirrhotic-patient-with-acute-non-variceal-upper-gastrointestinal-bleeding
#1
Xingshun Qi, Hongyu Li, Xiaodong Shao, Zhendong Liang, Xia Zhang, Ji Feng, Hao Lin, Xiaozhong Guo
Varices manifest as a major etiology of upper gastrointestinal bleeding in patients with chronic liver diseases, such as liver cirrhosis and hepatocellular carcinoma. By contrast, non-variceal upper gastrointestinal bleeding is rare. Pharmacological treatment differs between patients with variceal and non-variceal bleeding. Vasoconstrictors are recommended for the treatment of variceal bleeding, rather than non-variceal bleeding. In contrast, pump proton inhibitors are recommended for the treatment of non-variceal bleeding, rather than variceal bleeding...
December 2017: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/29327781/treatment-with-proton-pump-inhibitors-is-associated-with-increased-mortality-in-patients-with-pyogenic-liver-abscess
#2
D Bettinger, D Martin, S Rieg, M Schultheiss, N Buettner, R Thimme, T Boettler
BACKGROUND: Proton pump inhibitors (PPI) are often used in patients with gastro-esophageal reflux and peptic ulcer disease. A higher risk for infectious diseases and for pyogenic liver abscess has been reported in patients with prolonged PPI intake. Although many patients have ongoing PPI treatment after diagnosis of liver abscess, there are no data available that focus on the prognostic impact of PPI treatment in these patients. AIM: To analyse the effect of PPI treatment on mortality in patients with pyogenic liver abscesses...
January 12, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29319200/the-rise-and-fall-of-peptic-ulceration-a-disease-of-civilization
#3
REVIEW
Ian C Roberts-Thomson
Humans and Helicobacter pylori have evolved and adapted over tens of thousands of years. Yet peptic ulcer disease appeared to be rare prior to the 19th century. The prevalence of peptic ulcer disease increased between 1850 and 1900 and culminated in a cohort at high risk that was born at the end of the 19th century. This coincided with the provision of safe water and improvements in sanitation and personal hygiene. One hypothesis for the emergence of peptic ulcer disease focuses on the rate of development of atrophic gastritis induced by Helicobacter pylori...
January 10, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29314744/clinical-and-economic-implications-of-upper-gastrointestinal-adverse-events-in-asian-rheumatological-patients-on-long-term-non-steroidal-anti-inflammatory-drugs
#4
Lydia Say Lee Pok, Fatiha Hana Shabaruddin, Maznah Dahlui, Sargunan Sockalingam, Mohd Shahrir Mohamed Said, Azmillah Rosman, Ing Soo Lau, Liza Mohd Isa, Heselynn Hussein, Chin Teck Ng, Sanjiv Mahadeva
AIM: To determine the incidence and direct costs of NSAID-induced upper GI adverse events in Malaysian rheumatology patients. METHODS: A retrospective, multi-centre, cohort study of rheumatology patients on long-term NSAIDs was conducted. Clinical data of patients treated between 2010 and 2013 were collected for a 24-month follow-up period. The costs of managing upper GI adverse events were based on patient level resource use data. RESULTS: Six hundred and thirty-four patients met the inclusion criteria: mean age 53...
January 5, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29309400/comparison-table-drugs-for-gerd-and-peptic-ulcer-disease
#5
(no author information available yet)
No abstract text is available yet for this article.
January 15, 2018: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/29309399/drugs-for-gerd-and-peptic-ulcer-disease
#6
(no author information available yet)
No abstract text is available yet for this article.
January 15, 2018: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/29286503/population-morbidity-in-the-zaporizhzhia-nuclear-power-plant-observation-zone-as-an-integral-part-of-public-health
#7
I M Khomenko, N V Zakladna, N M Orlova
OBJECTIVE: To evaluate the health status of adult population living in the Ukrainian nuclear power industry obser vation zone on the example of Zaporizhzhia Nuclear Power Plant. MATERIALS AND METHODS: System review, analytic, sociological survey and statistical methods. RESULTS: There was established an increase in the incidence of digestive diseases among adult population in Nikopol of Dnipropetrovsk region, which is included in the Zaporizhzhia NPP observation zone...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29283964/the-american-association-for-the-surgery-of-trauma-uniform-grading-of-hemorrhagic-emergency-general-surgery-diseases
#8
Gail T Tominaga, Carlos V R Brown, John T Schulz, Ronald R Barbosa, Suresh Agarwal, Nathaniel McQuay, Garth Utter, Marie Crandall
Consistent grading of Emergency General Surgery (EGS) diseases is important for comparison of outcomes and development of EGS registries. The American Association for the Surgery of Trauma (AAST) Patient Assessment Committee has previously determined common EGS diseases and developed a grading system for measuring anatomic severity of 16 inflammatory/infectious EGS diseases. The specific aim of this project was to develop a uniform grading template for hemorrhagic EGS diseases managed by acute care surgeons and apply the template to common hemorrhagic EGS diseases...
December 28, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29282636/vonoprazan-a-novel-and-potent-alternative-in-the%C3%A2-treatment-of-acid-related-diseases
#9
REVIEW
Xiaoxiao Yang, Yueyue Li, Yiyuan Sun, Mingming Zhang, Chuanguo Guo, Iqtida Ahmed Mirza, Yan-Qing Li
Although proton pump inhibitors (PPIs) have been used widely, acid-related diseases are still associated with a huge burden on the health care system. Recently, the efficacy and safety of a new acid suppressant named vonoprazan in the treatment of acid-related diseases have been evaluated by a series of studies. As a novel potassium-competitive acid blocker, vonoprazan may provide reversible acid suppression by preventing K+ from binding to gastric H+/K+-ATPase. It has been clinically used for the short-term treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease and Helicobacter pylori (H...
December 27, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29260144/pneumatosis-cystoides-intestinalis-a-rare-cause-of-intraabdominal-free-air
#10
Hüseyin Pülat, Girayhan Çelik, Mehmet Zafer Sabuncuoğlu, Mehmet Fatih Benzin, Oktay Karaköse, Recep Çetin
Pneumatosis cystoides intestinalis is a rarely seen disease characterized by cysts filled with multiple gases in the wall of the small or large intestine. Many factors have been suggested in the etiology and pathogenesis, including peptic ulcer, pyloric stenosis, and endoscopic trauma. Because various clinical characteristics and symptoms are observed together, diagnosis is generally difficult. It may be a cause of free air observed on direct radiographs. Treatment is directed at the cause and although there is generally a good course, it can sometimes lead to severe complications...
2017: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29251014/amaranth-oil-reduces-accumulation-of-4-hydroxynonenal-histidine-adducts-in-gastric-mucosa-and-improves-heart-rate-variability-in-duodenal-peptic-ulcer-patients-undergoing-helicobacter-pylori-eradication
#11
Andriy Cherkas, Kamelija Zarkovic, Ana Čipak, Morana Jaganjac, Lidija Milković, Orest Abrahamovych, Ostap Yatskevych, Georg Waeg, Olha Yelisyeyeva, Neven Zarkovic
Helicobacter pylori-induced oxidative stress in gastric mucosa (GM) is a milieu for the development of chronic gastritis, duodenal peptic ulcer (DPU), gastric cancer and a number of extragastric diseases. Because our previous study revealed the accumulation of the protein adducts of lipid peroxidation product 4-hydroxynonenal (HNE) in GM, which persists after eradication of H. pylori, the aim of the study was to test whether Amaranth oil supplementation in addition to standard anti-Helicobacter treatment could prevent such accumulation of HNE in GM in H...
December 17, 2017: Free Radical Research
https://www.readbyqxmd.com/read/29246697/double-pylorus-a-rare-complication-of-peptic-ulcer-disease
#12
George A Salem, Donald Kastens
No abstract text is available yet for this article.
December 12, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29233672/time-latencies-of-helicobacter-pylori-eradication-after-peptic-ulcer-and-risk-of-recurrent-ulcer-ulcer-adverse-events-and-gastric-cancer-a-population-based-cohort-study
#13
Emma Sverdén, Nele Brusselaers, Karl Wahlin, Jesper Lagergren
BACKGROUND: Helicobacter pylori (H pylori) is associated with peptic ulcer disease and gastric cancer. AIM: To test how various lengths of delays in H pylori eradication therapy influence the risk of recurrent peptic ulcer, ulcer adverse events and gastric cancer. METHODS: This population-based nationwide Swedish cohort study included 29,032 patients receiving H pylori eradication therapy after peptic ulcer disease in 2005-2013. Pre-defined time intervals between date of peptic ulcer diagnosis and date of eradication therapy were analysed in relation to study outcomes...
December 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29224657/cta-as-an-adjuvant-tool-for-acute-intra-abdominal-or-gastrointestinal-bleeding
#14
REVIEW
Mitchell Storace, Jonathan G Martin, Jay Shah, Zachary Bercu
Hematemesis and acute postsurgical upper gastrointestinal hemorrhage are common emergent on-call consultations for the interventional radiologist. Upper GI bleleding (UGIB) is a relatively frequent problem. The incidence and mortality vary among patient populations, but studies have shown an overall incidence ranging from 36-172 cases per 100,000 adults per year, with a mortality rate of 5%-14%. The incidence is significantly higher in men. Peptic ulcer disease is the predominant etiology, responsible for 28%-59% of UGIB...
December 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29218061/a-comparative-study-of-efficacy-and-safety-of-two-eradication-regimens-for-helicobacter-pylori-infection
#15
Carmen Monica Preda, Doina Proca, Irina Sandra, Larisa Elena Fulger, Boroka Claudia Horeanga, Mircea Manuc, Teodora Manuc, Catalin Andrei Dutei, Mihaela Barbu, Letitia Tugui, Adriana-Corina Andrei, Bogdan Ionut Slavulete, Mircea Diculescu
Introduction: Helicobacter pylori infection is one of the most frequent diseases around the world, affecting about half of the world population. The infection is known to be associated with upper gastrointestinal diseases. The aim of this paper is to identify which of the following two first-line therapy options (ECA vs ECM - see abbreviations below) is more efficient and to assess the improvement in the quality of life among these patients. Material and Methods: 96 patients with proven Helicobacter pylori infection were divided in two treatment groups, as follows: 47 patients received a 10-day triple therapy with esomeprazole 80 mg/day, amoxicillin 2000 mg/day and clarithromycin 1000 mg/day (ECA) and the rest of 49 received a 10-day sequential therapy: esomeprazole 40 mg and amoxicillin 1000 mg twice daily for five days, followed by esomeprazole 40 mg, clarithromycin 500 mg and metronidazole 500 mg (ECM) twice daily for another five days...
September 2017: Mædica
https://www.readbyqxmd.com/read/29211362/clinical-differences-of-helicobacter-pylori-infection-in-children
#16
REVIEW
Barbara M Iwańczak, Anna M Buchner, Franciszek Iwańczak
Helicobacter pylori infection is widely spread all over the world. The prevalence of H. pylori infection in the world varies and depends on numerous factors such as age, ethnicity, geographical and socioeconomic status. Humans have been in a symbiotic relationship with this bacterium for thousands of years. However 10-20% of people infected with H. pylori are likely to develop gastroduodenal diseases such as peptic ulcer disease, iron deficiency anemia, gastric mucosal atrophy, metaplasia, dysplasia, MALT lymphoma, or gastric adenocarcinoma...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29208876/disease-pattern-among-children-attending-pediatric-outpatient-department-in-community-based-medical-college-hospital-bangladesh
#17
M Begum, M K Khan, M T Hossain, M Y Ali, F S Alam, S S Dipu, A H Hasan, M Nasrin
Disease pattern is based on socio-demographic characteristics, comprehensive health care services, and environmental variables like water supply, basic sanitation and housing, illness behavior like quick decision to arrive at health care facility, and treatment behavior like the modality of treatment they receive. The descriptive cross-sectional study was conducted during the period of January 2014 to December 2015. The study was carried out among 310 purposively selected children attended at Pediatric Outpatient department of Community Based Medical College Hospital, Bangladesh...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29207859/clinical-significance-of-risk-factors-for-asymptomatic-peptic-ulcer-disease
#18
Cheal Wung Huh, Byung-Wook Kim
No abstract text is available yet for this article.
November 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/29202336/colonization-localization-and-inflammation-the-roles-of-h-pylori-chemotaxis-in-vivo
#19
REVIEW
Kevin S Johnson, Karen M Ottemann
Helicobacter pylori is a Gram-negative bacterium that infects half of the world's population, causing gastritis, peptic ulcers, and gastric cancer. To establish chronic stomach infection, H. pylori utilizes chemotaxis, driven by a conserved signal transduction system. Chemotaxis allows H. pylori to sense an array of environmental and bacterial signals within the stomach, guiding its motility towards its preferred niche within the gastric mucosa and glands. Fine-tuned localization, regulated by the chemotaxis system, enables robust colonization during the acute stage of infection...
December 1, 2017: Current Opinion in Microbiology
https://www.readbyqxmd.com/read/29199171/gastroesophageal-reflux-disease-and-the-relationship-with-helicobacter-pylori
#20
Zeynel Mungan, Binnur Pınarbaşı Şimşek
After Helicobacter pylori was identified, and its relationship with peptic ulcer disease was exactly shown, the relationship of this bacterium with gastroesophageal reflux disease (GERD) gained momentum and discussions continue to this day. We reviewed the literature for the relationship between H. pylori and GERD. According to the existing data, there is no relationship between GERD and H. pylori presence. Successful eradication therapy does not have an impact on the emergence or exacerbation of GERD. However Barrett's esophagus and esophageal adenocarcinoma are less frequent, especially in the presence of CagA positive H...
December 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
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