keyword
https://read.qxmd.com/read/37776263/swincross-cross-modal-swin-transformer-for-head-and-neck-tumor-segmentation-in-pet-ct-images
#21
JOURNAL ARTICLE
Gary Y Li, Junyu Chen, Se-In Jang, Kuang Gong, Quanzheng Li
BACKGROUND: Radiotherapy (RT) combined with cetuximab is the standard treatment for patients with inoperable head and neck cancers. Segmentation of head and neck (H&N) tumors is a prerequisite for radiotherapy planning but a time-consuming process. In recent years, deep convolutional neural networks (DCNN) have become the de facto standard for automated image segmentation. However, due to the expensive computational cost associated with enlarging the field of view in DCNNs, their ability to model long-range dependency is still limited, and this can result in sub-optimal segmentation performance for objects with background context spanning over long distances...
September 30, 2023: Medical Physics
https://read.qxmd.com/read/37731054/triazine-based-covalent-organic-framework-embedded-with-cuprous-oxide-as-the-bioplatform-for-photoelectrochemical-aptasensing-escherichia-coli
#22
JOURNAL ARTICLE
Erfu Huo, Siyamak Shahab, Hao Dang, Qiaojuan Jia, Minghua Wang
A superior photoelectrochemical (PEC) aptasensor was manufactured for the detection of Escherichia coli (E. coli) based on a hybrid of triazine-based covalent-organic framework (COF) and cuprous oxide (Cu2 O). The COF synthesized using 1,3,5-tris(4-aminophenyl)-benzene (TAPB) and 1,3,5-triformylphloroglucinol (Tp) as building blocks acted as a scaffold for encapsulated Cu2 O nanoparticles (denoted as Cu2 O@TAPB-Tp-COF), which then was employed as the bioplatform for anchoring E. coli-targeted aptamer. Cu2 O@Cu@TAPB-Tp-COF demonstrated enhanced separation of the photogenerated carriers and photoabsorption ability and boosted photoelectric conversion efficiency...
September 20, 2023: Mikrochimica Acta
https://read.qxmd.com/read/37716023/additional-intraoperative-subpectoral-plane-block-vs-conventional-pain-control-a-comparison-of-shoulder-movement-in-patients-with-mastectomy
#23
RANDOMIZED CONTROLLED TRIAL
Sivaporn Pondeenana, Chao Saenghirunvattana, Patcharin Intarakhao, Sorasit Inchan, Panuwat Chuemor, Atthakorn Jarusriwanna
PURPOSE: Shoulder pain is common among mastectomy patients, with limiting shoulder mobility and negatively affecting their quality of life. Pectoral nerve blocks (PECs) have demonstrated efficacy in providing postoperative analgesia. We hypothesized that these nerve blocks could improve shoulder movement in patients undergoing mastectomy. METHODS: This prospective, randomized, double-blind controlled trial enrolled female participants diagnosed with breast cancer and scheduled for mastectomy...
December 2023: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/37667362/the-impact-of-pecs-ii-blockade-in-patients-undergoing-minimally-invasive-cardiac-surgery-a-prospective-randomized-controlled-and-triple-blinded-trial
#24
RANDOMIZED CONTROLLED TRIAL
Elisabeth Hoerner, Ottokar Stundner, Felix Naegele, Anna Fiala, Nikolaos Bonaros, Peter Mair, Johannes Holfeld, Lukas Gasteiger
BACKGROUND: Classic neuraxial techniques, such as thoracic epidural anesthesia, or alternative approaches like the paravertebral block, are not indicated in cardiac surgery due to increased bleeding risk. To provide satisfactory analgesia without the need for excessive opioid use, novel ultrasound techniques gained popularity and are of growing interest. The pectoralis nerve block II (PECS II) has been shown to provide good postoperative analgesia in modified radical mastectomy and might also be suitable for minimally invasive cardiac surgery...
September 4, 2023: Trials
https://read.qxmd.com/read/37665000/pecs-ii-block-for-cardiac-implantable-electronic-device-insertion-a-pilot-study
#25
JOURNAL ARTICLE
Mustafa Kilin, Ali Sait Kavakli, Arzu Karaveli, Tayfun Sugur, Gorkem Kus, Goksel Cagirci, Sakir Arslan
AIM: Some truncal blocks could provide adequate surgical anesthesia and postoperative analgesia in cardiac implantable electronic devices (CIED) insertion. The aim of this study was to evaluate the feasibility of the pectoral nerves (PECS) II block for CIED insertion. METHODS: PECS II blocks were performed on the left side using the ultrasound-guided single injection technique in all patients. The primary outcome for feasibility was the percentage of the cases completed without intraoperative additional local anesthesia...
September 4, 2023: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/37624474/chest-wall-and-abdominal-blocks-for%C3%A2-thoracic%C3%A2-and-abdominal-surgeries-a-review
#26
REVIEW
Richa Sharma, James Damiano, Ibrahim Al-Saidi, Anis Dizdarevic
PURPOSE OF REVIEW: The purpose of this review is to provide an up-to-date description and overview of the rapidly growing literature pertaining to techniques and clinical applications of chest wall and abdominal fascial plane blocks in managing perioperative pain. RECENT FINDINGS: Clinical evidence suggests that regional anesthesia blocks, including fascial plane blocks, such as pectoralis, serratus, erector spinae, transversus abdominis, and quadratus lumborum blocks, are effective in providing analgesia for various surgical procedures and have more desirable side effect profile when compared to traditional neuraxial techniques...
October 2023: Current Pain and Headache Reports
https://read.qxmd.com/read/37606838/aso-visual-abstract-a-randomized-single-blinded-study-comparing-pre-and-post-mastectomy-pecs-block-for-postoperative-pain-management-in-bilateral-mastectomy-with-immediate-reconstruction
#27
JOURNAL ARTICLE
I M Lizarraga, K Huang, B Yalamuru, S L Mott, Z A Sibenaller, J N Keith, S Sugg, L M Erdahl, M Seering
No abstract text is available yet for this article.
August 22, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37604608/a-dual-model-immobilization-free-photoelectrochemical-visual-colorimetric-bioanalysis-based-on-microemulsion-self-assemblies-mediated-multifunctional-signal-amplification-strategy
#28
JOURNAL ARTICLE
Wenchao Geng, Linsheng Xue, Yuling Li, Jiangying Ji, Xinxin Yuan, Lihua Ding, Ruiying Yang
Herein, a novel silver ion-loaded gold microemulsion assemblies (Au/Ag+ MAs) mediated multifunctional signal amplification strategy was proposed to construct a sensitive immobilization-free photoelectrochemical (PEC)/colorimetric biosensor for carcinoembryonic antigen (CEA) detection. Through the sandwiched reaction among CEA, the CEA aptamer (DNA1) loaded on the Au nanoparticles (NPs) functionalized iron oxide (Fe3 O4 ) nanospheres and another CEA aptamer (DNA2) immobilized on Au/Ag+ MAs, a complex is formed and acquired by magnetic separation...
October 9, 2023: Analytica Chimica Acta
https://read.qxmd.com/read/37578321/tuning-band-alignment-at-grain-boundaries-for-efficiency-enhancement-in-cu-2-znsns-4-solar-cells
#29
JOURNAL ARTICLE
Wenjie Li, Weimin Li, Guo Chen, Liyun Wu, Jun Zhang, Ming Chen, Guohua Zhong, Junyi Zhu, Ye Feng, Hao Zeng, Chunlei Yang
Conducting atomic force microscopy has been performed for a fundamental understanding of the mechanism responsible for the lower power conversion efficiency (PCE) of Cu2 ZnSnS4 (CZTS) solar cells than that of CuIn1- x Ga x Se2 (CIGS) solar cells. The difference in efficiency is partly attributed to the distinctly different band alignment between the grain boundaries (GBs) and grain interior (GI) for the two materials. While CIGS shows type-II band alignment, CZTS was discovered to demonstrate type-I band alignment with the conduction band shifting downward while the valence band shifting upward at the GBs...
August 14, 2023: ACS Nano
https://read.qxmd.com/read/37572764/evaluation-of-the-effectiveness-of-artificial-intelligence-for-ultrasound-guided-peripheral-nerve-and-plane-blocks-in-recognizing-anatomical-structures
#30
JOURNAL ARTICLE
Irfan Gungor, Berrin Gunaydin, Beyza M Buyukgebiz Yeşil, Selin Bagcaz, Miray Gozde Ozdemir, Gozde Inan, Suna O Oktar
BACKGROUND: We aimed to assess the accuracy of artificial intelligence (AI) based real-time anatomy identification for ultrasound-guided peripheral nerve and plane block in eight regions in this prospective observational study. METHODS: After obtaining ethics committee approval and written informed consent from 40 healthy volunteers (20 men and 20 women, between 18 and 72 years old), an ultrasound device installed with AI software (Nerveblox, SmartAlfa, Turkey) were used to scan regions of the cervical plexus, brachial plexus, pectoralis (PECS), rectus sheet, femoralis, canalis adductorius, popliteal, and ESP by three anesthesiology trainees...
October 2023: Annals of Anatomy
https://read.qxmd.com/read/37564866/combined-fascial-plane-blocks-as-the-sole-regional-anesthesia-technique-for-breast-surgery-in-high-risk-patients
#31
JOURNAL ARTICLE
Raghu S Thota, Ramkiran Seshadri, Amit R Panigrahi
The quest for an effective regional anaesthesia technique in breast surgery has always been eluded by its apparent complexity. Various techniques had been described as anaesthetic techniques for breast cancer surgeries. Fascial plane blocks had been used as analgesic techniques for this procedure. We describe a case series of 12 patients who were given a combination of erector spinae plane block (ESP), Pectoralis I (Pecs I) and serratus anterior plane (SAP) block as sole anaesthetic technique with high risk surgical morbidity...
2023: Journal of Anaesthesiology, Clinical Pharmacology
https://read.qxmd.com/read/37526752/a-randomized-single-blinded-study-comparing-preoperative-with-post-mastectomy-pecs-block-for-post-operative-pain-management-in-bilateral-mastectomy-with-immediate-reconstruction
#32
RANDOMIZED CONTROLLED TRIAL
Ingrid M Lizarraga, K Huang, B Yalamuru, S L Mott, Z A Sibenaller, J N Keith, S L Sugg, L M Erdahl, M Seering
BACKGROUND: Ultrasound-guided pectoralis muscle blocks (PECS I/II) are well established for postoperative pain control after mastectomy with reconstruction. However, optimal timing is unclear. We conducted a randomized controlled single-blinded single-institution trial comparing outcomes of block performed pre-incision versus post-mastectomy. METHOD: Patients with breast cancer undergoing bilateral mastectomy with immediate expander/implant reconstruction were randomized to receive ultrasound-guided PECS I/II either pre-incision (PreM, n = 17) or post-mastectomy and before reconstruction (PostM, n = 17)...
October 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37487346/people-with-young-onset-dementia-and-their-family-caregivers-discussing-euthanasia-a-qualitative-analysis-of-their-considerations
#33
JOURNAL ARTICLE
Romy Van Rickstal, Aline De Vleminck, Kenneth Chambaere, Lieve Van den Block
OBJECTIVES: Research showed that people with young-onset dementia and their family caregivers raised the topic of euthanasia when talking about the broader topic of advance care planning. A better understanding of what people address and why may inform the evolving landscape of physician assisted dying. This study aimed to explore the considerations that people with young-onset dementia and their family caregivers expressed on euthanasia. METHODS: A secondary qualitative analysis on interviews with 10 Belgian people with young-onset dementia and 25 family caregivers, using constant comparative analysis...
July 12, 2023: Patient Education and Counseling
https://read.qxmd.com/read/37433096/efficient-photoelectrochemical-hydrogen-generation-using-eco-friendly-giant-inp-znse-core-shell-quantum-dots
#34
JOURNAL ARTICLE
Jiabin Liu, Shuai Yue, Hui Zhang, Chao Wang, David Barba, François Vidal, Shuhui Sun, Zhiming M Wang, Jiming Bao, Haiguang Zhao, Gurpreet Singh Selopal, Federico Rosei
InP quantum dots (QDs) are promising building blocks for use in solar technologies because of their low intrinsic toxicity, narrow bandgap, large absorption coefficient, and low-cost solution synthesis. However, the high surface trap density of InP QDs reduces their energy conversion efficiency and degrades their long-term stability. Encapsulating InP QDs into a wider bandgap shell is desirable to eliminate surface traps and improve optoelectronic properties. Here, we report the synthesis of "giant" InP/ZnSe core/shell QDs with tunable ZnSe shell thickness to investigate the effect of the shell thickness on the optoelectronic properties and the photoelectrochemical (PEC) performance for hydrogen generation...
July 11, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/37393350/pectolinarigenin-inhibits-bladder-urothelial-carcinoma-cell-proliferation-by-regulating-dna-damage-autophagy-pathways
#35
JOURNAL ARTICLE
Zhao Deng, Dexin Shen, Mengxue Yu, Fenfang Zhou, Danni Shan, Yayun Fang, Wan Jin, Kaiyu Qian, Shenjuan Li, Gang Wang, Yi Zhang, Lingao Ju, Yu Xiao, Xinghuan Wang
Pectolinarigenin (PEC), an active compound isolated from traditional herbal medicine, has shown potential anti-tumor properties against various types of cancer cells. However, its mechanism of action in bladder cancer (BLCA), which is one of the fatal human carcinomas, remains unexplored. In this study, we first revealed that PEC, as a potential DNA topoisomerase II alpha (TOP2A) poison, can target TOP2A and cause significant DNA damage. PEC induced G2/M phase cell cycle arrest via p53 pathway. Simultaneously, PEC can perform its unique function by inhibiting the late autophagic flux...
July 1, 2023: Cell Death Discovery
https://read.qxmd.com/read/37377822/effect-of-erector-spinae-block-and-pectoralis-block-on-quality-of-recovery-and-analgesia-after-modified-radical-mastectomy-a-randomised-controlled-study
#36
RANDOMIZED CONTROLLED TRIAL
Md Hammad Mohsin, Reetu Verma, Hemlata, Dinesh Singh, Sarita Singh, Kulranjan Singh
OBJECTIVES: Post-operative pain after a modified radical mastectomy ranges from moderate to severe. Pectoralis (PECS) block has been found to be more effective than erector spinae block in reducing pain and the consumption of rescue analgesia in the post-operative period. This study aimed to compare the effect of erector spinae block and PECS block on the quality of recovery after modified radical mastectomy using the quality of recovery (QoR-40) score. METHODS: This randomised controlled study was conducted at King George's Medical University, Lucknow, India, from 9th October 2020 to 9th October 2021...
May 2023: Sultan Qaboos University Medical Journal
https://read.qxmd.com/read/37356081/a-direct-contact-photocurrent-direction-switching-biosensing-platform-based-on-in-situ-formation-of-cn-qds-tio-2-nanodiscs-and-double-supported-3d-dna-walking-amplification
#37
JOURNAL ARTICLE
Wenchao Geng, Guihua Jiang, Huimin Liu, Linsheng Xue, Lihua Ding, Yuling Li, Yongjun Wu, Ruiying Yang
Herein, a direct-contact photocurrent-direction-switching photoelectrochemical (PEC) biosensing platform for the ultrasensitive and selective detection of soluble CD146 (sCD146) is reported for the first time via in situ formation of carbon nitride quantum dots (CN QDs)/titanium dioxide (TiO2 ) nanodiscs with the double-supported 3D DNA walking amplification. In this platform, metal organic frameworks (MOFs)-derived porous TiO2 nanodiscs exhibit excellent anodic photocurrent, whereas a single-stranded auxiliary DNA (ssDNA) as biogate is absorbed onto the TiO2 nanodiscs to block active sites...
June 25, 2023: Small
https://read.qxmd.com/read/37334077/updates-on-enhanced-recovery-after-surgery-protocols-for-plastic-surgery-of-the-breast-and-future-directions
#38
JOURNAL ARTICLE
Nicholas F Lombana, Ishan M Mehta, Caiwei Zheng, Reuben A Falola, Andrew M Altman, Michel H Saint-Cyr
INTRODUCTION: Perioperative pain control is an important component of any plastic surgery practice. Due to the incorporation of Enhanced Recovery after Surgery (ERAS) protocols, reported pain level, opioid consumption, and hospital length of stay numbers have decreased significantly. This article provides an up-to-date review of current ERAS protocols in use, reviews individual aspects of ERAS protocols, and discusses future directions for the continual improvement of ERAS protocols and control of postoperative pain...
2023: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/37328251/fabrication-and-nano-engineering-of-non-noble-metal-coupled-plasmonic-heterostructures-for-ultrasensitive-photoelectrochemical-immunoassays
#39
JOURNAL ARTICLE
Xingxing Meng, Tianxiang Hang, Hui Zhou, Zongrui Zhang, Chuanping Li
To achieve reliable and ultrasensitive detection for disease markers in PEC bioanalysis, constructing and nano-engineering of ideal photoelectrodes and signal transduction strategies are of vital importance. Herein, a non-/noble metal coupled plasmonic nanostructure (TiO2 /r-STO/Au) was tactically designed with high-efficient PEC performance. Evidenced by the DFT and FDTD calculations, the reduced SrTiO3 (r-STO) was found to support the localized surface plasmon resonance due to the sufficiently increased and delocalized local charge in r-STO...
August 29, 2023: Analytica Chimica Acta
https://read.qxmd.com/read/37306272/comparing-the%C3%A2-quality-of%C3%A2-analgesia-with-ultrasound-guided-pectoral-nerve-block-and-serratus-anterior-plane-block-ii-in-patients-undergoing-modified-radical-mastectomy-a%C3%A2-randomised-clinical-trial
#40
RANDOMIZED CONTROLLED TRIAL
Abdelrhman Alshawadfy, Shimaa A Al-Touny
INTRODUCTION: Despite the recent use of serratus anterior plane (SAP) and pectoral nerve (PECS) blocks for pain management following breast surgery, there are insufficient data comparing their analgesic benefits. This study aimed to compare the quality of analgesia for PECS and SAP blocks in patients having modified radical mastectomy (MRM). MATERIAL AND METHODS: This trial enrolled 50 adult female patients scheduled for MRM under anaesthesia. Patients were randomly allocated to two groups...
2023: Anaesthesiology Intensive Therapy
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