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3-D Printing

Ariana Torres-Knoop, Ivan Kryven, Verena Schamboeck, Piet D Iedema
In the printing, coating and ink industries, photocurable systems are becoming increasingly popular and multi-functional acrylates are one of the most commonly used monomers due to their high reactivity (fast curing). In this paper, we use molecular dynamics and graph theory tools to investigate the thermo-mechanical properties and topology of hexanediol diacrylate (HDDA) polymer networks. The gel point was determined as the point where a giant component was formed. For the conditions of our simulations, we found the gel point to be around 0...
April 18, 2018: Soft Matter
Aditi Naik, Jae Joon Kim, Özlem Usluer, D Leonardo Gonzalez Arellano, Ethan B Secor, Antonio Facchetti, Mark C Hersam, Alejandro L Briseno, James J Watkins
The scalable fabrication of high-resolution electrodes and interconnects is necessary to enable advanced, high-performance, printed and flexible electronics. Here, we demonstrate the direct printing of graphene patterns with feature widths from 300 µm to ~310 nm by liquid-bridge-mediated nanotransfer molding. This solution-based technique enables residue-free printing of graphene patterns on a variety of substrates with surface energies between ~43 and 73 mN m-1 . Using printed graphene source and drain electrodes, high-performance organic field-effect transistors (OFETs) are fabricated with single-crystal rubrene (p-type) and fluorocarbon-substituted dicyanoperylene-3,4:9,10-bis(dicarboximide) (PDIF-CN2 ) (n-type) semiconductors...
April 18, 2018: ACS Applied Materials & Interfaces
C Powell, D Bamber, J Long, R Garratt, J Brown, S Rudge, T Morris, N Bhupendra Jaicim, R Plachcinski, S Dyson, E M Boyle, I St James-Roberts
BACKGROUND: During the first 4 months of age, approximately 20% of infants cry a lot without an apparent reason. Most research has targeted the crying, but the impact of the crying on parents, and subsequent outcomes, need to receive equal attention. This study reports the findings from a prospective evaluation of a package of materials designed to support the well-being and mental health of parents who judge their infant to be crying excessively. The resulting "Surviving Crying" package comprised a website, printed materials, and programme of Cognitive Behaviour Therapy-based support sessions delivered to parents by a qualified practitioner...
April 17, 2018: Child: Care, Health and Development
Peter A J Pijpker, Joep Kraeima, Max J H Witjes, D L Marinus Oterdoom, Maarten H Coppes, Rob J M Groen, Jos M A Kuijlen
BACKGROUND: Accurate cervical screw insertion is of paramount importance considering the risk of damage to adjacent vital structures. Recent research in 3-dimensional (3D) technology describes the advantage of patient-specific drill guides for accurate screw positioning, but consensus about the optimal guide design and the accuracy is lacking. OBJECTIVE: To find the optimal design and to evaluate the accuracy of individualized 3D-printed drill guides for lateral mass and pedicle screw placement in the cervical and upper thoracic spine...
April 5, 2018: Operative Neurosurgery (Hagerstown, Md.)
Louisa Chou, Lisa Ellis, Michelle Papandony, K L Maheeka D Seneviwickrama, Flavia M Cicuttini, Kaye Sullivan, Andrew J Teichtahl, Yuanyuan Wang, Andrew M Briggs, Anita E Wluka
BACKGROUND: Optimal management of osteoarthritis requires active patient participation. Understanding patients' perceived health information needs is important in order to optimize health service delivery and health outcomes in osteoarthritis. We aimed to review the existing literature regarding patients' perceived health information needs for OA. METHODS: A systematic scoping review was performed of publications in MEDLINE, EMBASE, CINAHL and PsycINFO (1990-2016)...
2018: PloS One
D John, M Zimmermann, A Böker
A simple route towards patchy particles with anisotropic patches with respect to a different functionality and directionality is presented. This method is based on microcontact printing of positively charged polyethylenimine (PEI) on silica particles using wrinkled stamps. Due to the wrinkled surface, the number of patches on the particles as well as the distance between two patches can be controlled.
April 16, 2018: Soft Matter
Hanie Yousefi, M Monsur Ali, Hsuan-Ming Su, Carlos D M Filipe, Tohid F Didar
Here, we report the development of a transparent, durable, and flexible sensing surface that generates a fluorescence signal in the presence of a specific target bacterium. This material can be used in packaging, and it is capable of monitoring microbial contamination in various types of food products in real time without having to remove the sample or the sensor from the package. The sensor was fabricated by covalently attaching picoliter-sized microarrays of an E. coli-specific RNA-cleaving fluorogenic DNAzyme probe (RFD-EC1) to a thin, flexible, and transparent cyclo-olefin polymer (COP) film...
April 6, 2018: ACS Nano
Francesco Simonetti, Isaak L Satow, Alex J Brath, Kaden C Wells, John Porter, Brian Hayes, Kenneth Davis
Recent advances in computational methods, materials science, and new manufacturing processes are resulting in an unprecedented design flexibility which is driving the geometrical complexity of the components found in modern structures and machines. For safety-critical components, the geometrical complexity poses a significant challenge to the sensitivity of the existing nondestructive evaluation (NDE) methods available for the detection of manufacturing defects or damage that develops while a component is in service...
April 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Cheng Wei, Chunhui Li, Magdalena Szewczyk-Bieda, Dilip Upreti, Stephen Lang, Zhihong Huang, Ghulam Nabi
OBJECTIVE: To test the diagnostic accuracy of SWE for the detection and phenotypic characterisation of PCa compared with whole-mount radical prostatectomy histopathology. MATERIALS AND METHODS: This was a prospective protocol-driven diagnostic accuracy study. 212 consecutive men undergoing laparoscopic radical prostatectomy (LRP) for clinically localised PCa were recruited into the study. Quantitative stiffness data of the prostate gland was obtained in each patient using an endocavitary transrectal transducer before LRP and compared with detailed histopathological examination of radical prostatectomy specimen using 3-D printing mold based technology ensuring improved image-histology orientation...
March 29, 2018: Journal of Urology
Nanyan Rao, Kai Chen, Qihua Yang, Jinmin Niu
PURPOSE: In this proof-of-concept study, we proposed 3-D-printed mold-guided breast-conserving surgery (BCS) in breast cancer patients. PATIENTS AND METHODS: Pathologically confirmed and eligible breast cancer patients received magnetic resonance imaging examinations before BCS. The information on the shape, size, and location of the tumor relative to the nipple was extracted and analyzed. We used a 3-D printing technique to produce a mold to guide BCS for breast cancer patients...
February 20, 2018: Clinical Breast Cancer
C Severini, D Azzollini, M Albenzio, A Derossi
3D printing technology was employed to obtain snacks with a designed cylindrical geometry from wheat flour dough enriched by ground larvae of Yellow mealworms (Tenebrio molitor) as novel source of proteins. The main microstructural features, overall quality, and nutritional attributes were studied as a function of formulation, time and temperature of baking. The addition of ground insects up to 20 g/100 g (d.b.) resulted in softer dough. This caused an overflow in dough deposition producing the increase in diameter, height and weight of snacks...
April 2018: Food Research International
Eugen B Petcu, Rajiv Midha, Erin McColl, Aurel Popa-Wagner, Traian V Chirila, Paul D Dalton
After many decades of biomaterials research for peripheral nerve regeneration, a clinical product (the nerve guide), is emerging as a proven alternative for relatively short injury gaps. This review identifies aspects where 3D printing can assist in improving long-distance nerve guide regeneration strategies. These include (1) 3D printing of the customizable nerve guides, (2) fabrication of scaffolds that fill nerve guides, (3) 3D bioprinting of cells within a matrix/bioink into the nerve guide lumen and the (4) establishment of growth factor gradients along the length a nerve guide...
March 23, 2018: Biofabrication
P He, J R Brent, H Ding, J Yang, D J Lewis, P O'Brien, B Derby
Fully printed humidity sensors based on two-dimensional (2D) materials are described. Monolayer graphene oxide (GO) and few-layered black phosphorus (BP) flakes were dispersed in low boiling point solvents suitable for inkjet printing. The humidity sensors were fabricated by printing GO and BP sensing layers on printed silver nanoparticle electrodes. The electrical response of the GO and BP sensors to humidity levels ranges from 11 to 97% relative humidity, which revealed a high capacitance sensitivity of 4...
March 22, 2018: Nanoscale
Kena Song, Zirui Wang, Ruchuan Liu, Guo Chen, Liyu Liu
Exploring the complicated development of tumors and metastases needs a deep understanding of the physical and biological interactions between cancer cells and their surrounding microenvironments. One of the major challenges is the ability to mimic the complex 3-D tissue microenvironment that particularly influences cell proliferation, migration, invasion, and apoptosis in relation to the extracellular matrix (ECM). Traditional cell culture is unable to create 3-D cell scaffolds resembling tissue complexity and functions, and, in the past, many efforts were made to realize the goal of obtaining cell clusters in hydrogels...
March 21, 2018: International Journal of Molecular Sciences
Alexandre Khaldi, Daniel Falk, Katarina Bengtsson, Ali Maziz, Daniel Filippini, Nathaniel D Robinson, Edwin W H Jager
There is a need for soft actuators in various biomedical applications in order to manipulate delicate objects such as cells and tissues. Soft actuators are able to adapt to any shape and limit the stress applied to delicate objects. Conjugated polymer actuators, especially in the so-called trilayer configuration, are interesting candidates for driving such micromanipulators. However, challenges involved in patterning the electrodes in a trilayer with individual contact have prevented further development of soft micromanipulators based on conjugated polymer actuators...
March 20, 2018: ACS Applied Materials & Interfaces
Cheng-Hsin Cheng, Hao-Yu Chuang, Hung-Lin Lin, Chun-Lin Liu, Chun-Hsu Yao
OBJECT: The aim of this research was to evaluate the surgical outcome of a new three-dimensional printing (3DP) technique using prefabrication molds and polymethyl methacrylate (PMMA). PATIENTS AND METHODS: The study included 10 patients with large skull defects (>100 cm2 ) who underwent cranioplasty. The causes of the skull defects were trauma (6), bone resorption (2), tumor (1), and infection (1). Before the operation, computed tomography (CT) scans were used to create a virtual plan, and these were then converted to 3-dimensional (3-D) images...
March 9, 2018: Clinical Neurology and Neurosurgery
Tao Li, Mingzheng Peng, Zezheng Yang, Xiaojun Zhou, Yuan Deng, Chuan Jiang, Ming Xiao, Jinwu Wang
To promote vascularization of tissue-engineered bone, IFN-γ polarizing macrophages to M1 was loaded on 5% calcium silicate/β-tricalcium phosphate (CaSiO3 -β-TCP) scaffolds. IFN-γ and Si released from the scaffold were designed to polarize M1 and M2 macrophages, respectively. β-TCP, CaSiO3 -β-TCP, and IFN-γ@CaSiO3 -β-TCP were fabricated and biocompatibilities were evaluated. Polarizations of macrophages were detected by flow cytometry. Human umbilical vein endothelial cells with GFP were cultured and induced on Matrigel with conditioned culture medium extracted from culture of macrophages loaded on scaffolds for evaluating angiogenesis...
March 13, 2018: Acta Biomaterialia
G Zhou, K P Wang, H W Liu, L Wang, X F Xiao, D D Dou, Y B Fan
Owing to low bearing capacity and efficiency, traditional filters or adsorbents for removal of contaminants like crystal violet (CV) dye required frequent replacement. Besides, the combination of three-dimensional (3D) printing and bionics could break the constraints of traditional configuration. In this study, a novel depth-type hybrid polylactic acid (PLA)@graphene oxide (GO)/chitosan (CS) sponge filter with bionic fish-mouth structure was prepared and fabricated, assisted by 3D printing and double freeze-drying technology, according to the theories of vertical cross-step filtration and swirling flow...
March 9, 2018: International Journal of Biological Macromolecules
B Molinero-Abad, D Izquierdo, L Pérez, I Escudero, M J Arcos-Martínez
An anodic stripping voltammetric method is reported in this study for the determination of sub-nanomolar Pb concentration using disposable sensors, each consisting of three (counter, working and reference) screen-printed electrodes. Sensor performance was optimized for the determination of Pb through several surface modifications, by using single-walled carbon nanotubes, electro-reduced graphene oxide and gold nanoparticles. A scanning electron microscopy study of the deposition of electrogenerated gold nanoparticles of various sizes on the working electrode surface showed that spherical nanoparticles of around 100 nm provided the best results...
May 15, 2018: Talanta
Heath E Matheson, Ariana M Familiar, Sharon L Thompson-Schill
Theories of embodied cognition propose that we recognize tools in part by reactivating sensorimotor representations of tool use in a process of simulation. If motor simulations play a causal role in tool recognition then performing a concurrent motor task should differentially modulate recognition of experienced vs. non-experienced tools. We sought to test the hypothesis that an incompatible concurrent motor task modulates conceptual processing of learned vs. non-learned objects by directly manipulating the embodied experience of participants...
March 2, 2018: Psychological Research
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