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3-D Printing

Wyatte C Hall, Dongmei Li, Timothy D V Dye
OBJECTIVES: To assess the influence of hearing loss on child behavioral diagnoses, and socioemotional and behavior status. METHODS: We analyzed US National Health Interview Survey (NHIS) child data, years 2011 to 2015, for associations between reported hearing loss and relevant NHIS items. RESULTS: Compared with hearing children, NHIS respondents with a deaf child were more likely to report developmental delays (adjusted odds ratio [AOR] = 11...
June 21, 2018: American Journal of Public Health
Michael A Bohl, Michael A Mooney, Garrett J Repp, Claudio Cavallo, Peter Nakaji, Steve W Chang, Jay D Turner, U Kumar Kakarla
Introduction The Barrow Biomimetic Spine project is an ongoing effort to develop a three-dimensional (3D)-printed synthetic spine model with high anatomical and biomechanical fidelity to human tissue. The purpose of this study was to evaluate the biomechanical performance of an L4-L5 3D-printed synthetic spine model in a lordotic correction test after Schwab grade 2 osteotomies as compared to human cadaveric spines that have undergone the same osteotomies and lordotic correction. Methods Ten different L4-L5 synthetic spine models were 3D printed...
April 17, 2018: Curēus
Elliot S Bishop, Sami Mostafa, Mikhail Pakvasa, Hue H Luu, Michael J Lee, Jennifer Moriatis Wolf, Guillermo A Ameer, Tong-Chuan He, Russell R Reid
Advances in three-dimensional (3D) printing have increased feasibility towards the synthesis of living tissues. Known as 3D bioprinting, this technology involves the precise layering of cells, biologic scaffolds, and growth factors with the goal of creating bioidentical tissue for a variety of uses. Early successes have demonstrated distinct advantages over conventional tissue engineering strategies. Not surprisingly, there are current challenges to address before 3D bioprinting becomes clinically relevant...
December 2017: Genes & Diseases
Sean D McGarry, Sarah L Hurrell, Kenneth A Iczkowski, William Hall, Amy L Kaczmarowski, Anjishnu Banerjee, Tucker Keuter, Kenneth Jacobsohn, John D Bukowy, Marja T Nevalainen, Mark D Hohenwalter, William A See, Peter S LaViolette
PURPOSE: This study aims to combine multiparametric magnetic resonance imaging (MRI) and digitized pathology with machine learning to generate predictive maps of histologic features for prostate cancer localization. METHODS AND MATERIALS: Thirty-nine patients underwent MRI prior to prostatectomy. After surgery, tissue was sliced according to MRI orientation using patient-specific 3-dimensionally printed slicing jigs. Whole-mount sections were annotated by our pathologist and digitally contoured to differentiate the lumen and epithelium...
April 24, 2018: International Journal of Radiation Oncology, Biology, Physics
Smadar Z Patael, Emily A Farris, Jessica M Black, Roeland Hancock, John D E Gabrieli, Laurie E Cutting, Fumiko Hoeft
OBJECTIVE: The ultimate goal of reading is to understand written text. To accomplish this, children must first master decoding, the ability to translate printed words into sounds. Although decoding and reading comprehension are highly interdependent, some children struggle to decode but comprehend well, whereas others with good decoding skills fail to comprehend. The neural basis underlying individual differences in this discrepancy between decoding and comprehension abilities is virtually unknown...
2018: PloS One
Florian B Imhoff, Knut Beitzel, Philip Zakko, Elifho Obopilwe, Andreas Voss, Bastian Scheiderer, Daichi Morikawa, Augustus D Mazzocca, Robert A Arciero, Andreas B Imhoff
Background: Derotational osteotomy of the distal femur allows the anatomic treatment of patellofemoral maltracking due to increased femoral antetorsion. However, such rotational osteotomy procedures have a high potential of intended/unintended changes of frontal alignment. Purpose/Hypothesis: The purpose of this study was to perform derotational osteotomy of the distal femur and to demonstrate the utility of a novel trigonometric approach to address 3-dimensional (3D) changes on 2-dimensional imaging (axial computed tomography [CT] and frontal-plane radiography)...
June 2018: Orthopaedic Journal of Sports Medicine
Aykut Aksit, Daniel N Arteaga, Miguel Arriaga, Xun Wang, Hirobumi Watanabe, Karen E Kasza, Anil K Lalwani, Jeffrey W Kysar
The cochlea, or inner ear, is a space fully enclosed within the temporal bone of the skull, except for two membrane-covered portals connecting it to the middle ear space. One of these portals is the round window, which is covered by the Round Window Membrane (RWM). A longstanding clinical goal is to reliably and precisely deliver therapeutics into the cochlea to treat a plethora of auditory and vestibular disorders. Standard of care for several difficult-to-treat diseases calls for injection of a therapeutic substance through the tympanic membrane into the middle ear space, after which a portion of the substance diffuses across the RWM into the cochlea...
June 8, 2018: Biomedical Microdevices
Samer Bou Jawde, Bradford J Smith, Adam Sonnenberg, Jason H T Bates, Bela Suki
OBJECTIVE: While many studies rely on flow and pressure measurements in small animal models of respiratory disease, such measurements can however be inaccurate and difficult to obtain. Thus, the goal of this study was to design and implement an easy to manufacture and accurate sensor capable of monitoring flow. APPROACH: We designed and 3-D printed a flowmeter and utilized parametric (resistance and inertance) and nonparametric (polynomial and Volterra series) system identification to characterize the device...
June 7, 2018: Physiological Measurement
Christen J Boyer, David H Ballard, Jungmi W Yun, Adam Y Xiao, Jeffery A Weisman, Mansoureh Barzegar, Jonathan Steven Alexander
PURPOSE: Cell migration/invasion assays are widely used in commercial drug discovery screening. 3D printing enables the creation of diverse geometric restrictive barrier designs for use in cell motility studies, permitting on-demand assays. Here, the utility of 3D printed cell exclusion spacers (CES) was validated as a cell motility assay. METHODS: A novel CES fit was fabricated using 3D printing and customized to the size and contour of 12 cell culture plates including 6 well plates of basal human brain vascular endothelial (D3) cell migration cells compared with 6 well plates with D3 cells challenged with 1uM cytochalasin D (Cyto-D), an F-actin anti-motility drug...
June 4, 2018: Pharmaceutical Research
Evan D Chinoy, Jeanne F Duffy, Charles A Czeisler
Consumer electronic devices play an important role in modern society. Technological advancements continually improve their utility and portability, making possible the near-constant use of electronic devices during waking hours. For most people, this includes the evening hours close to bedtime. Evening exposure to light-emitting (LE) devices can adversely affect circadian timing, sleep, and alertness, even when participants maintain a fixed 8-hour sleep episode in darkness and the duration of evening LE-device exposure is limited...
May 2018: Physiological Reports
Jingxin Zhao, Yachang Ma, Dong Han, Yu Jin
Objective: To investigate the application value of three-dimensional (3-D) printing technology in the operation of distal tibia fracture involving epiphyseal plate injury for teenagers. Methods: The retrospective analysis was conducted on the clinical data of 16 cases of children patients with distal tibia fracture involving epiphyseal plate injury undergoing the operation by using of 3-D printing technology between January 2014 and December 2015. There were 12 males and 4 females with an age of 9-14 years (mean, 12...
October 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
Geng Yang, Jia Deng, Gaoyang Pang, Hao Zhang, Jiayi Li, Bin Deng, Zhibo Pang, Juan Xu, Mingzhe Jiang, Pasi Liljeberg, Haibo Xie, Huayong Yang
Surface electromyography signal plays an important role in hand function recovery training. In this paper, an IoT-enabled stroke rehabilitation system was introduced which was based on a smart wearable armband (SWA), machine learning (ML) algorithms, and a 3-D printed dexterous robot hand. User comfort is one of the key issues which should be addressed for wearable devices. The SWA was developed by integrating a low-power and tiny-sized IoT sensing device with textile electrodes, which can measure, pre-process, and wirelessly transmit bio-potential signals...
2018: IEEE Journal of Translational Engineering in Health and Medicine
Johannes G G Dobbe, Giuliana Caiti, Albert W Schreurs, Simon D Strackee, Maikel Beerens, Geert J Streekstra
Conventional corrective osteotomy surgery is based on 2-D imaging for planning and evaluation of bone positioning. In this feasibility study we propose and evaluate the use of 3-D preoperative planning and design of a custom rimmed wedge to be inserted into the osteotomy gap. The shape of the wedge provides 3-D bone positioning as planned, while the rims keep the bone segments in place. The method is evaluated experimentally using 3-D printed radii specimens of five different malunion patients, as well as in a human cadaver specimen...
May 22, 2018: Medical Engineering & Physics
Meryam Shikara, Christopher J Rizzi, Brian Zelip, Fleesie Hubbard, Kavita T Vakharia, Amal Isaiah, Jewel D Greywoode, Kalpesh T Vakharia
Importance: The introduction and evaluation of a novel technique to create nasal prostheses with 3-dimensional (3-D) imaging software may circumvent the need for an anaplastologist. Objectives: To describe a novel computer algorithm for the creation of a 3-D model of a nose and to evaluate the similarity of appearance of the nasal prosthesis with that of the individual's nose. Design, Setting, and Participants: A prospective pilot study with a cross-sectional survey was conducted from August 1 to October 31, 2016, at a tertiary care academic center...
May 10, 2018: JAMA Otolaryngology—Head & Neck Surgery
Min Wu, Jianzhong Guan, Yuzhou Xiao, Zhaodong Wang, Xiaotian Chen, Zhi Zhao, Kuankuan Zhang, Jun Zhu
Objective: To evaluate the effectiveness of three-dimensional (3-D) printing assisting minimally invasive for intraarticular calcaneal fractures with percutaneous poking reduction and cannulate screw fixation. Methods: A retrospective analysis was performed of the 19 patients (19 feet) with intraarticular calcaneal fracture who had been treated between March 2015 and May 2016. There were 13 males and 6 females with an average age of 38.2 years (range, 24-73 years)...
November 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
Daiqing Wei, Cui Li, Yangbo Xu
Objective: To review the current research progress of three-dimensional (3-D) printing technique in foot and ankle surgery. Methods: Recent literature associated with the clinical application of 3-D printing technique in the field of medicine, especially in foot and ankle surgery was reviewed, summarized, and analyzed. Results: At present, 3-D printing technique has been applied in foot and ankle fracture, segmental bone defect, orthosis, corrective surgery, reparative and reconstructive surgery which showed satisfactory effectiveness...
August 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
Suhani Ghai, Yogesh Sharma, Neha Jain, Mrinal Satpathy, Ajay Kumar Pillai
Three-dimensional (3-D) printing is a method of manufacturing in which materials like plastic or metal are deposited onto one another in layers to produce a 3-D object. Because of the complex anatomy of craniomaxillofacial structures, full recovery of craniomaxillofacial tissues from trauma, surgeries, or congenital malformations is extremely challenging. 3-D printing of scaffolds, tissue analogs, and organs has been proposed as an exciting alternative to address some of these key challenges in craniomaxillofacial surgery...
May 25, 2018: Oral and Maxillofacial Surgery
Oliver Skocek, Tobias Nöbauer, Lukas Weilguny, Francisca Martínez Traub, Chuying Naomi Xia, Maxim I Molodtsov, Abhinav Grama, Masahito Yamagata, Daniel Aharoni, David D Cox, Peyman Golshani, Alipasha Vaziri
In the version of this Brief Communication originally published online, ref. 21 included details for a conference paper (Pegard, N. C. et al. Paper presented at Novel Techniques in Microscopy: Optics in the Life Sciences, Vancouver, BC, Canada, 12-15 April 2015). The correct reference is the following: Pégard, N. C. et al. Optica 3, 517-524 (2016). This error has been corrected in the print, HTML and PDF versions of the paper.
May 21, 2018: Nature Methods
Michael Chung, Norbert Radacsi, Colin Robert, Edward D McCarthy, Anthony Callanan, Noel Conlisk, Peter R Hoskins, Vasileios Koutsos
Background: There is a potential for direct model manufacturing of abdominal aortic aneurysm (AAA) using 3D printing technique for generating flexible semi-transparent prototypes. A patient-specific AAA model was manufactured using fused deposition modelling (FDM) 3D printing technology. A flexible, semi-transparent thermoplastic polyurethane (TPU), called Cheetah Water (produced by Ninjatek, USA), was used as the flexible, transparent material for model manufacture with a hydrophilic support structure 3D printed with polyvinyl alcohol (PVA)...
2018: 3D printing in medicine
Stefanie Lochmann, Julia Grothe, Kai Eckhardt, Desirée Leistenschneider, Lars Borchardt, Stefan Kaskel
Nanoimprint lithography is proposed as a highly versatile method for the production of nanostructured supercapacitors (micro-supercapacitors, MSC). Liquid sucrose- and lignin-precursor printing produces patterns with high quality and a line width down to 500 nm. The liquid-carbon-precursor NIL-printing approach enables nitrogen doping to achieve an increased supercapacitor performance for aqueous electrolytes (Li2SO4). The lines are interconverted into nanoporous carbon materials (d ≈ 1 nm) with high specific surface area (>1000 m2 g-1) to form stable structures reaching specific resistivities as low as ρ = 3...
May 21, 2018: Nanoscale
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