Robert Darnell, Alanna Brown, Emma Laing, Julia Edwards, David A Harrison, Joseph C Manning, Mark J Peters, Padmanabhan Ramnarayan, Samiran Ray, Zia Sadique, Barnaby R Scholefield, Dermot Shortt, Lamprini Lampro, Carly Au, Kathy M Rowan, Paul Mouncey, David P Inwald
OBJECTIVES: Management of hypotension is a fundamental part of pediatric critical care, with cardiovascular support in the form of fluids or vasoactive drugs offered to every hypotensive child. However, optimal blood pressure (BP) targets are unknown. The PRotocolised Evaluation of PermiSSive BP Targets Versus Usual CaRE (PRESSURE) trial aims to evaluate the clinical and cost-effectiveness of a permissive mean arterial pressure (MAP) target of greater than a fifth centile for age compared with usual care...
April 17, 2024: Pediatric Critical Care Medicine