Thomas Renson, Margaret M Kelly, Hallgrimur Benediktsson, Nele Grundhoefer, Nadia Luca, Paivi Miettunen, Marinka Twilt, Silviu Grisaru, Andrew Wade, Anke Banks, Aurore Fifi-Mah, Lorraine Hamiwka, Susanne Benseler
BACKGROUND: In anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), histopathological assessment of affected tissue is often necessary for diagnosis and assessment of disease extent. There is a requirement for validated non-invasive biomarkers to avoid the need for serial tissue biopsies. METHODS: A systematic review of scientific databases from 2012 until present was performed to identify studies fulfilling the inclusion criteria. Studies were assessed for quality using the Strengthening the Reporting of Observational Studies in Epidemiology checklist for cohort, case-control and cross-sectional studies and the Risk of Bias Assessment tool for Non-randomised Studies, or the Cochrane Risk of Bias tool 2...
February 9, 2024: RMD Open