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Addison Jobe, Ajay Kalra, Elise Ibendahl
Growing populations and industrialized agriculture practices have eradicated much of the United States wetlands along river floodplains. One program available for the restoration of floodplains is the Conservation Reserve Program (CRP). The current research explores the effects CRP land change has on flooding zones, utilizing Flood Modeller and HEC-RAS. Flood Modeller is proven a viable tool for flood modeling within the United States when compared to HEC-RAS. Application of the software is used in the Nodaway River system located in the western halves of Iowa and Missouri to model effects of introducing new forest areas within the region...
March 10, 2018: Journal of Environmental Management
Marissa Penna-Martinez, Natalie Filmann, Dimitra Bogdanou, Firouzeh Shoghi, Sabine Huenecke, Ralf Schubert, Eva Herrmann, Ulrike Koehl, Eystein S Husebye, Klaus Badenhoop
OBJECTIVES: On the basis of the immunomodulatory actions of vitamin D (VD), we investigated the effects of high-dose VD therapy over a 3 mo period on the immune response in patients with Addison's disease (AD). METHODS: This randomized, controlled, crossover trial included 13 patients with AD who received either cholecalciferol (4000 IU/d) for 3 mo followed by 3 mo placebo oil or the sequential alternative placebo followed by verum. Glucocorticoid replacement doses remained stable...
December 2, 2017: Nutrition
Lisa Letzkus, Nancy Addison, Lauren Turner, Mark Conaway, Beth Quatrara
PROBLEM: Paroxysmal sympathetic hyperactivity (PSH) is a complicated phenomenon that presents as autonomic instability and muscle overactivity in individuals who experience severe brain injury. Identifying potential modifiable environmental nociceptive stimuli is necessary for developing interventions that impact clinical outcomes. OBJECTIVE: The aim of this study was to identify physical environmental nociceptive stimuli that could hinder recovery for children who experience PSH after severe brain injury...
April 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
Akshaya Shanmugam, Mohammad Usmani, Addison Mayberry, David L Perkins, Daniel E Holcomb
Miniaturized imaging devices have pushed the boundaries of point-of-care imaging, but existing mobile-phone-based imaging systems do not exploit the full potential of smart phones. This work demonstrates the use of simple imaging configurations to deliver superior image quality and the ability to handle a wide range of biological samples. Results presented in this work are from analysis of fluorescent beads under fluorescence imaging, as well as helminth eggs and freshwater mussel larvae under white light imaging...
2018: PloS One
Ilias Attaye, Merel van Andel, Albertus Jozef Kooter
A 67-year-old Caucasian woman with no prior medical history was admitted to our hospital with complaints of generalised weakness, nausea, diarrhoea and weight loss. The patient suffered from tachycardia and hypotension. Blood tests revealed Graves' thyrotoxicosis and the patient was treated accordingly. However, patient's health continued to decline rapidly and further tests revealed a concomitant Addisonian crisis. Additional treatment with corticosteroids led to a full recovery. It is well known that autoimmune endocrine disorders tend to cluster...
March 5, 2018: BMJ Case Reports
Marta Fichna, Magdalena Żurawek, Bartłomiej Budny, Hanna Komarowska, Elżbieta Niechciał, Piotr Fichna, Marek Ruchała
INTRODUCTION    RANTES (Regulated on Activation, Normal T-cell Expressed and Secreted) chemokine, the product of CCL5 gene, is involved in trafficking immune cells into the inflammation site. It acts as co-activator of T cells and promotes polarization of the immune response towards the Th1 profile. In autoimmune Addison's disease (AAD) adrenal cortex is gradually destroyed by adrenal-specific immune cell infiltration. RANTES might be implicated in autoimmune adrenal failure through recruitment and activation of the immune cells...
March 2, 2018: Polish Archives of Internal Medicine
Diane Addison, Abigail Baim-Lance, Lauren Suchman, Benjamin Katz, Carol-Ann Swain, Kelly Piersanti, Clemens Steinbock, Steven Sawicki, Bruce Agins, Denis Nash
As part of the System Linkages and Access to Care Initiative, 12 HIV service delivery organizations in New York implemented one of the following three interventions to improve linkage to and retention in HIV care at their site: Peer Support, Appointment Procedures, and Anti-Retroviral Treatment and Access to Services. Aggregate process measure data describing intervention delivery, in conjunction with qualitative findings to help explain barriers and facilitators to achieving full implementation were examined...
February 28, 2018: AIDS and Behavior
Matthew W Semler, Wesley H Self, Jonathan P Wanderer, Jesse M Ehrenfeld, Li Wang, Daniel W Byrne, Joanna L Stollings, Avinash B Kumar, Christopher G Hughes, Antonio Hernandez, Oscar D Guillamondegui, Addison K May, Liza Weavind, Jonathan D Casey, Edward D Siew, Andrew D Shaw, Gordon R Bernard, Todd W Rice
BACKGROUND: Both balanced crystalloids and saline are used for intravenous fluid administration in critically ill adults, but it is not known which results in better clinical outcomes. METHODS: In a pragmatic, cluster-randomized, multiple-crossover trial conducted in five intensive care units at an academic center, we assigned 15,802 adults to receive saline (0.9% sodium chloride) or balanced crystalloids (lactated Ringer's solution or Plasma-Lyte A) according to the randomization of the unit to which they were admitted...
March 1, 2018: New England Journal of Medicine
Addison Williams Andrews, Richard Pine
BACKGROUND AND PURPOSE: Nocturnal lower limb cramps are sudden, intensely painful, and can decrease sleep, increase anxiety, and reduce quality of life. The purpose of this case report is to describe the effectiveness of an evidence-based physical therapy intervention for a person with lower limb cramps. CASE DESCRIPTION: The patient was a 34-year-old female who presented with idiopathic bilateral lower limb foot pain and cramps. INTERVENTION: Rehabilitation addressed muscle strength, joint mobility, soft tissue extensibility, and biomechanical influences during functional movement, for a total of seven sessions over seven weeks...
February 26, 2018: Physiotherapy Theory and Practice
Jacopo Manso, Raffaele Pezzani, Riccardo Scarpa, Nicoletta Gallo, Corrado Betterle
Autoimmune Addison's disease (AAD) is the most frequent cause of adrenocortical insufficiency. The natural history of AAD usually comprises five consecutive stages with the first stage characterized by the increase of plasma renin consistent with the impairment of pars glomerulosa, which is usually the first affected layer of the adrenal cortex. We describe a 19-year-old female with Hashimoto's thyroiditis (HT) who underwent an autoantibody screening due to having the personal and family history of other autoimmune diseases in the absence of relevant clinical manifestations...
February 26, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
Sibongile Mafu, Yezhang Ding, Katherine M Murphy, Omar Yaacoobi, John Bennett Addison, Qiang Wang, Zhouxin Shen, Steven Paul Briggs, Joerg Bohlmann, Gabriel Castro-Falcón, Chambers C Hughes, Mariam Betsiashvili, Alisa Huffaker, Eric A Schmelz, Philipp Zerbe
Terpenoids are a major component of maize (Zea mays) chemical defenses that mediate responses to herbivores, pathogens and other environmental challenges. Here, we describe the biosynthesis and elicited production of a class of maize diterpenoids, named dolabralexins. Dolabralexin biosynthesis involves the sequential activity of two diterpene synthases, the ENT-COPALYL DIPHOSPHATE SYNTHASE (ZmAN2) and KAURENE SYNTHASE-LIKE 4 (ZmKSL4). Together, ZmAN2 and ZmKSL4 form the diterpene hydrocarbon dolabradiene. In addition, we biochemically characterized a cytochrome P450 monooxygenase, ZmCYP71Z16, which catalyzes the oxygenation of dolabradiene to yield the epoxides 15,16-epoxydolabrene (epoxydolabrene) and 3β-hydroxy-15,16-epoxydolabrene (epoxydolabranol)...
February 23, 2018: Plant Physiology
D P Laverty, K Fairbrother, O Addison
BACKGROUND: This systematic review aims to evaluate the survival of retaining or replacing deciduous teeth in hypodontia patients with a variety of prosthetic tooth replacement options, to evaluate prognostic factors associated with retaining deciduous teeth, and report on patient based outcomes with these treatment modalities. METHODS: MEDLINE, The Cochrane Central Register of Controlled Trials and Science Direct databases were searched (01/1980 - 08/2017) for studies reporting outcomes associated with retaining or replacing deciduous teeth via prosthetic means in adult hypodontia patients...
February 20, 2018: Community Dental Health
Yue Zhang, Owen Addison, Fei Yu, Brendy C Rincon Troconis, John R Scully, Alison J Davenport
There is increasing concern regarding the biological consequences of metal release from implants. However, the mechanisms underpinning implant surface degradation, especially in the absence of wear, are often poorly understood. Here the synergistic effect of albumin and H 2 O 2 on corrosion of Ti6Al4V in physiological saline is studied with electrochemical methods. It is found that albumin induces a time-dependent dissolution of Ti6Al4V in the presence of H 2 O 2 in physiology saline. Potentiostatic polarisation measurements show that albumin supresses dissolution in the presence of H 2 O 2 at short times (<24 h) but over longer time periods (120 h) it significantly accelerates corrosion, which is attributed to albumin-catalysed dissolution of the corrosion product layer resulting in formation of a thinner oxide film...
February 16, 2018: Scientific Reports
Soha Rostaminia, Addison Mayberry, Deepak Ganesan, Benjamin Marlin, Jeremy Gummeson
The ability to monitor eye closures and blink patterns has long been known to enable accurate assessment of fatigue and drowsiness in individuals. Many measures of the eye are known to be correlated with fatigue including coarse-grained measures like the rate of blinks as well as fine-grained measures like the duration of blinks and the extent of eye closures. Despite a plethora of research validating these measures, we lack wearable devices that can continually and reliably monitor them in the natural environment...
June 2017: Proc ACM Interact Mob Wearable Ubiquitous Technol
Daniela Barbieri Hauschild, Anauã Franco Rosa, Julia Carvalho Ventura, Eliana Barbosa, Emília Addison Machado Moreira, Norberto Ludwig Neto, Yara Maria Franco Moreno
OBJECTIVE: To evaluate the association between nutritional status, lung function and morbidity in a 36-month cohort in children and adolescents with cystic fibrosis. METHODS: Prospective cohort of children and adolescents with cystic fibrosis aged 1-15 years. At the baseline, the nutritional status was determined by weight-for-height and body mass index-for-age for children <2 years and ≥2 years, respectively, and classified as: nutritional failure, nutritional risk and acceptable; and by the 50th percentile, according to the World Health Organization (WHO) growth charts...
January 15, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Daniel Addison, Patrick R Lawler, Hamed Emami, Sumbal A Janjua, Pedro V Staziaki, Travis R Hallett, Orla Hennessy, Hang Lee, Bálint Szilveszter, Michael Lu, Negar Mousavi, Matthew G Nayor, Francesca N Delling, Javier M Romero, Lori J Wirth, Annie W Chan, Udo Hoffmann, Tomas G Neilan
BACKGROUND AND PURPOSE: Interventions to reduce the risk for cerebrovascular events (CVE; stroke and transient ischemic attack [TIA]) after radiotherapy (RT) for head and neck cancer (HNCA) are needed. Among broad populations, statins reduce CVEs; however, whether statins reduce CVEs after RT for HNCA is unclear. Therefore, we aimed to test whether incidental statin use at the time of RT is associated with a lower rate of CVEs after RT for HNCA. METHODS: From an institutional database we identified all consecutive subjects treated with neck RT from 2002 to 2012 for HNCA...
January 2018: Journal of Stroke
Gesine Meyer, Maike Koch, Eva Herrmann, Jörg Bojunga, Klaus Badenhoop
PURPOSE: Several studies have shown a reduced quality of life (QoL) in patients with Addison's disease (AD), but investigations of QoL over a long-term course are lacking. Adrenal crises (AC) are life-threatening complications in AD. The purpose of this prospective study was to test whether the repeated use of QoL-questionnaires can detect prodromal periods of an AC. METHODS: 110 patients with AD were asked to complete the disease specific-QoL questionnaire AddiQoL and a short questionnaire about adverse events once monthly over a period of ten months...
January 31, 2018: Endocrine
Mulugeta Gizaw, Jeffrey Thompson, Addison Faglie, Shih-Yu Lee, Pierre Neuenschwander, Shih-Feng Chou
Wound healing is a complex tissue regeneration process that promotes the growth of new tissue to provide the body with the necessary barrier from the outside environment. In the class of non-healing wounds, diabetic wounds, and ulcers, dressing materials that are available clinically (e.g., gels and creams) have demonstrated only a slow improvement with current available technologies. Among all available current technologies, electrospun fibers exhibit several characteristics that may provide novel replacement dressing materials for the above-mentioned wounds...
January 27, 2018: Bioengineering
C Paul Scott, Laurel Milberg, Richard Addison
No abstract text is available yet for this article.
January 2018: International Journal of Psychiatry in Medicine
Sandra Shenouda, Khaled Al-Farawi, Jenna Dolan, Susan L Flesher
Idiopathic intracranial hypertension is a diagnosis of exclusion defined by elevated intracranial pressure without mass lesions or hydrocephalus. Causes of idiopathic intracranial hypertension include obesity, vitamin derangements, antibiotics, corticosteroids, and autoimmune disorders. Cushing's disease and Addison's disease have been associated with idiopathic intracranial hypertension. Secondary adrenal insufficiency following withdrawal of inhaled corticosteroids has been found to be a relatively common phenomenon...
2018: SAGE open medical case reports
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