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Osama Mahmoud, Ahmed El-Assmy, Mohamed Kamal, Albeer Ashamallah, Hassan Abol-Enein
PURPOSE: To evaluate the necessity of chronic alkali therapy in non-complicated orthotopic ileal neobladders with normal renal function. MATERIALS AND METHODS: This is a prospective study that included 200 male patients who underwent radical cystectomy and ileal W neobladder for invasive bladder carcinoma between January 1993 and December 2013. The studied patients included 100 consecutive patients who were maintained on regular alkali therapy since surgery and 100 consecutive patients who stopped the use of alkali treatment after initial 3 months postoperative with minimum postoperative observation time of 1 year...
January 2017: International Urology and Nephrology
Ahmed El-Assmy, Osama Mahmoud, Mohamed Kamal, Wafaa Soliman, Albeer Ashamallah, Niveen El-Wakeel, Hassan Abol-Enein
OBJECTIVE: To characterize the standard physical, chemical, and microscopic characteristics of urine in patients with noncomplicated orthotopic ileal neobladders. MATERIALS AND METHODS: This is a prospective study that included 100 male patients who underwent radical cystectomy and ileal neobladder between 1993 and 2013. All included patients were in a good health and having satisfactory function of the reservoirs with normal upper tract with a minimum 1-year postoperative follow-up...
October 2016: Urology
Shivali Justa, Ranjana W Minz, Shashi Anand, Mukut Minz
BACKGROUND: The role of neopterin as a marker of cell-mediated immunity for immunological monitoring after transplantation is of great potential interest. Neopterin levels among hepatitis C virus (HCV)-positive recipients of living-donor renal transplantation (LDRT) have not been previously described. METHODS: Twenty-two HCV-positive (group I) and 10 HCV-negative (group II) recipients of LDRT were serially monitored for serum neopterin levels by enzyme-linked immunosorbent assay (ELISA)...
2015: Biomarker Insights
Shokoufeh Bonakdaran, Banafsheh Kharaqani
AIM: The relationship between elevated serum uric acid level and metabolic syndrome (MS) has been debated. There is no data concerning this relation in Iranian population-based studies. The aim of this study was to determine the prevalence of hyperuricamia and its association with MS in type 2 diabetes mellitus (DM). PATIENTS AND METHODS: This was a cross- sectional study in 1978 diabetic patients. Hyperuricamia was defined as uric acid ≥ 7 and ≥ 5.5 mg/dl for men and women respectively...
March 2014: Current Diabetes Reviews
Hala Mostafa Goma
BACKGROUND: scoliosis correction surgery is common in children, and adolescents. Deliberate hypotension is indicated in scoliosis correction procedures, because bloodless field is needed for exposure of the nerve roots, and to decrease the need for blood transfusion. Protection of the kidneys during deliberate hypotension is essential. The ideal hypotensive drug maintains the renal function and the urine output during the period of hypotension. Aim of this study is to compare Prostaglandin E1, and Esmolol hypotensive effects, bleeding score, and their effects on the serum creatnine, and urine output...
February 2012: Middle East Journal of Anesthesiology
Zhijian Wang, Hua Zou, Yanhong Yu, Yancheng Song
OBJECTIVE: Preeclampsia is a prevalent and potentially devastating complication of pregnancy. Intercellular adhesion molecule-1 (ICAM-1) was reported to be involved in the pathogenesis of the disease. Therefore we hypothesized anti-ICAM-1 monoclonal antibody (mAb) could be a therapeutic choice for preeclampsia. The objective of this study was to evaluate its therapeutic effects using a rat model of preeclampsia. METHODS: Timed pregnant Wistar rats were intravenously injected endotoxin and then randomized to receive either anti-ICAM-1 mAb or saline...
June 2012: Journal of Maternal-fetal & Neonatal Medicine
Jennifer A Frontera, Thomas Kalb
The need for organ donation has become a growing concern over that last decade as the gap between organ donors and those awaiting transplant widens. According to UNOS, as of 8/2009, there were 102,962 patients on the transplant waiting list and only 6,004 donors in 2009 ( Accessed 4/8/2009). In 2008, an estimated 17 patients died each day awaiting transplant ( Though currently most organ donations come after brain death (DND or donation after neurological death), tissue donation (cornea, skin, bone, and musculoskeletal tissue), and donation after cardiac death (DCD) and are also possible...
February 2010: Neurocritical Care
J H Cheng
95 cases of cancer patients were treated with large dose of Cisplatinum. They were randomly divided into treated group with Chinese medicinal herbs (49 cases) and control group with hydration treatment (46 cases). Multiple indexes were selected to observe effect on renal function. The result showed that the level of blood urea nitrogen (BUN), creatnine (Cr), beta 2 microglobulin (beta 2-MG), urea N-acetyl-beta-glucosaminidase (NAG) of treated group lowered. After treatment the difference of BUN, Cr between the two groups was significant (P < 0...
June 1994: Chinese Journal of Integrated Traditional and Western Medicine
R Sarac, V Sedlak-Vadoc
Clearance of the endogenous creatinine is a simple method for application, it is relatively cheap and applicable in almost all surroundings, but it is not reliable enough when the obtained results are concerned. This report shows the results of determining this clearance in comparison with radiosotope clearance 51 cr-EDTA, referent for clinical research, in 52 outpatients with primary and secondary kidney diseases. It was found that values of clearance of the endogene creatinine (Clkr) are significantly lower than the clearance 51 Cr-EDTA (ClEDTA) (t = 2...
1993: Medicinski Pregled
J R Darm, N V Bhagavan, A G Scottolini
A 56-year-old Samoan man with a documented history of hypertension, who presented with atrial fibrillation and hypotension, quickly developed renal failure with a serum urea nitrogen of 1.370 g/L and a serum creatinine of 92 mg/L. After hydration of the patient, the creatinine value became normal in two days, the urea nitrogen in four days. The urinary creatinine output during the first 24 h of hospitalization was 3.7 g. This case illustrates the rapidity with which unusually large amounts of creatinine (more commonly seen in chronic renal failure) can accumulate and be excreted in pre-renal failure...
November 1979: Clinical Chemistry
C Y Pak, R Kaplan, H Bone, J Townsend, O Waters
A test was developed to diagnose various forms of hypercalciuria. A two-hour urine sample after an overnight fast and a four-hour urine sample after 1 g of calcium by mouth were tested for calcium, cyclic AMP and creatinine. The 24 patients with absorptive hypercalciuria had normocalcemia and normal fasting urinary calcium (less than 0.11 mg per milligram of urinary creatnine). Urinary calcium was high (greater than or equal to 0.2 mg per milligram of creatinine) after a calcium load. Of the 28 patients with primary hyperparathyroidism (resorptive hypercalciuria), 25 had hypercalcemia and 21 had high fasting urinary calcium...
March 6, 1975: New England Journal of Medicine
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