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Gynaecology

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https://www.readbyqxmd.com/read/29786947/does-general-experience-affect-self-assessment
#1
Parisa Rezaiefar, Kelly Forse, Joseph K Burns, Sharon Johnston, Elizabeth Muggah, Claire Kendall, Douglas Archibald
BACKGROUND: The assessment of clinical competence is critical in medical education. Understanding the effect of general experience on a physician's self-assessment would help design more effective curricula and evaluations of procedural skills in postgraduate training and continuing professional development (CPD). In this observational study, we assessed the effect of general experience on the correlation between confidence and competence amongst experienced clinicians (ECs) and postgraduate trainees (PGTs) when learning an office-based procedure in pessary care...
May 22, 2018: Clinical Teacher
https://www.readbyqxmd.com/read/29786828/oral-contraceptives-for-pain-associated-with-endometriosis
#2
REVIEW
Julie Brown, Tineke J Crawford, Shree Datta, Andrew Prentice
BACKGROUND: Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The combined oral contraceptive pill (COCP) is widely used to treat pain occurring as a result of endometriosis, although the evidence for its efficacy is limited. OBJECTIVES: To determine the effectiveness, safety and cost-effectiveness of oral contraceptive preparations in the treatment of painful symptoms ascribed to the diagnosis of laparoscopically proven endometriosis...
May 22, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29785682/the-modified-memorial-symptom-assessment-scale-short-form-a-modified-response-format-and-rational-scoring-rules
#3
J L Sharp, K Gough, M C Pascoe, A Drosdowsky, V T Chang, P Schofield
PURPOSE: The Memorial Symptom Assessment Scale Short Form (MSAS-SF) is a widely used symptom assessment instrument. Patients who self-complete the MSAS-SF have difficulty following the two-part response format, resulting in incorrectly completed responses. We describe modifications to the response format to improve useability, and rational scoring rules for incorrectly completed items. METHODS: The modified MSAS-SF was completed by 311 women in our Peer and Nurse support Trial to Assist women in Gynaecological Oncology; the PeNTAGOn study...
May 21, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29784140/telephone-follow-up-after-treatment-for-endometrial-cancer-a-qualitative-study-of-patients-and-clinical-nurse-specialists-experiences-in-the-endcat-trial
#4
S Williamson, K Beaver, A Gardner, P Martin-Hirsch
PURPOSE: Endometrial cancer is the sixth most common female cancer worldwide. There is little evidence that routine hospital surveillance increases survival or decreases morbidity following treatment. Gynaecology Oncology clinical nurse specialists (CNSs) are ideally placed to provide the care, information and support to enable women with a gynaecological cancer to self-manage and live well. A multi-centre randomised controlled trial (RCT) compared hospital follow-up (HFU) with telephone follow-up (TFU) by CNSs...
June 2018: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/29782641/the-analgesic-efficacy-and-pharmacokinetics-of-epidural-oxycodone-after-gynaecologic-laparotomy-a-randomised-double-blind-double-dummy-comparison-with-intravenous-administration
#5
Panu Piirainen, Hannu Kokki, Heidi Hautajärvi, Veli-Pekka Ranta, Merja Kokki
AIM: To compare the analgesic efficacy of epidural and i.v. oxycodone at the same dose. METHODS: In this randomised, double-blind, double-dummy clinical trial 30 women, aged 24-67 years, undergoing elective gynaecologic laparotomy were administrated either i.v. saline and epidural oxycodone 0.1 mg·kg-1 (EPI-group; n=15) or i.v. oxycodone 0.1 mg·kg-1 and epidural saline (IV-group; n=15). For multimodal analgesia patients received i.v. paracetamol and dexketoprofen, and a triple-mixture epidural infusion after the first four postoperative hours...
May 21, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29781548/multi-omics-in-high-grade-serous-ovarian-cancer-biomarkers-from-genome-to-the-immunome
#6
Cole Clifford, Natasha Vitkin, Sarah Nersesian, Gillian Reid-Schachter, Julie-Ann Francis, Madhuri Koti
Epithelial ovarian cancer (EOC) is a lethal gynaecological disease that imposes significant burden on health care and patient quality of life. High-grade serous carcinoma of the ovary (HGSC) is the most prevalent histological type of EOC. A vast majority of HGSC cases are diagnosed at late stages of the disease, limiting the opportunity for clinical intervention and resulting in a 10-year survival rate of <20%. Recent innovations in high-throughput molecular analysis of patient-derived specimens may address these clinical challenges by providing an enhanced understanding of the molecular aetiology of ovarian cancer, in addition to offering several opportunities for rational biomarker and targeted therapy discovery...
May 21, 2018: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29777898/a-survey-of-health-professionals-views-on-acceptable-gestational-age-and-termination-of-pregnancy-for-fetal-anomaly
#7
Lisa Crowe, Ruth H Graham, Stephen C Robson, Judith Rankin
Termination of pregnancy for fetal anomaly is legal in the UK with no upper limit, if two doctors, in good faith, agree "there is a substantial risk that if the child were born it would suffer from such physical or mental abnormalities as to be seriously handicapped". This is Clause E of the Human Fertlisation and Embryology Act. The most commonly sighted Clause is C, which states "the pregnancy has not exceeded its twenty-fourth week and that the continuance of the pregnancy would involve risk, greater than if the pregnancy were terminated, of injury to the physical or mental health of the pregnant woman"...
May 16, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29774779/image-guided-radiation-therapy-for-post-operative-gynaecologic-cancer-patient-set-up-verification-with-and-without-implanted-fiducial-markers
#8
Donna H Murrell, Andrew Warner, Quinn Benwell, Wendy Wells, Danielle Scott, Vikram Velker, George Hajdok, David P D'Souza
BACKGROUND: Intensity modulated radiotherapy (IMRT) is increasingly being used to treat gynaecological malignancies in the postoperative setting. The purpose of this study was to evaluate the use of image-guided radiotherapy (IGRT) using cone-beam computed tomography (CBCT) with fiducial markers for daily localization. MATERIAL AND METHODS: A single institution study was performed of consecutive cervical or endometrial cancer patients receiving adjuvant external beam radiotherapy (n = 15)...
May 18, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29771998/risk-factors-for-inappropriate-blood-requisition-among-hospitals-in-tanzania
#9
Wilhellmuss I Mauka, Tara B Mtuy, Michael J Mahande, Sia E Msuya, Innocent B Mboya, Abdul Juma, Rune N Philemon
BACKGROUND: Blood is a critical aspect of treatment in life saving situations, increasing demand. Blood requisition practices greatly effect sufficient supply in blood banks. This study aimed to determine the risk factors for inappropriate blood requisition in Tanzania. METHODS: This was a cross sectional study using secondary data of 14,460 patients' blood requests from 42 transfusion hospitals. Primary data were obtained by using cluster-sampling design. Data were analysed using a two-level mixed-effects Poisson regression to determine fixed-effects of individual-level factors and hospital level factors associated with inappropriate blood requests...
2018: PloS One
https://www.readbyqxmd.com/read/29771224/discipline-specific-competency-based-curricula-for-leadership-learning-in-medical-specialty-training
#10
Sandra Turner, Ming-Ka Chan, Judy McKimm, Graham Dickson, Timothy Shaw
Purpose Doctors play a central role in leading improvements to healthcare systems. Leadership knowledge and skills are not inherent, however, and need to be learned. General frameworks for medical leadership guide curriculum development in this area. Explicit discipline-linked competency sets and programmes provide context for learning and likely enhance specialty trainees' capability for leadership at all levels. The aim of this review was to summarise the scholarly literature available around medical specialty-specific competency-based curricula for leadership in the post-graduate training space...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29769772/oral-hygiene-status-gingival-status-periodontal-status-and-treatment-needs-among-pregnant-and-nonpregnant-women-a-comparative-study
#11
Meena Kashetty, Sagar Kumbhar, Smita Patil, Prashant Patil
Objectives: The gingival and periodontal changes during pregnancy are well known. Gingivitis is the most prevalent oral manifestations associated with pregnancy. The hormonal and vascular changes that accompany pregnancy are known to exaggerate the inflammatory response to the local irritants. Hence, a study was designed to assess oral hygiene status, gingival status, periodontal status, and treatment needs (TNs) among pregnant and nonpregnant women. Materials and Methods: A cross-sectional study was conducted among 120 pregnant and 120 nonpregnant women of 18-44 years age attending the Outpatient Department of Gynaecology and Obstetrics in Government Hospital of Belgaum city, Karnataka, India...
March 2018: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29765558/the-fallopian-tube-microbiome-implications-for-reproductive-health
#12
Elise S Pelzer, Dana Willner, Melissa Buttini, Louise M Hafner, Christina Theodoropoulos, Flavia Huygens
Objective: There is a paucity of data characterizing the microbiota of the female upper genital tract, which controversially is described as a sterile site. We examine whether the fallopian tube harbours an endogenous microbial community. Design: This prospective study collected from women undergoing total hysterectomy or salpingectomy-oophorectomy. Setting: Private hospital gynaecology department. Patients: Fallopian tubes were collected from women diagnosed with benign disease or for prophylaxis...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29765296/peripartum-haemorrhage-haemostatic-aspects-of-the-new-german-pph-guideline
#13
REVIEW
Heiko Lier, Christian von Heymann, Wolfgang Korte, Dietmar Schlembach
Summary Peripartum haemorrhage remains one of the main causes of maternal mortality world-wide. The German, Austrian and Swiss Societies of Gynaecology and Obstetrics have updated the current guidelines for the treatment of peripartum haemorrhage together with the German Society of Anaesthesiology and Intensive Care Medicine and the Society of Thrombosis and Haemostasis Research. The recommendations have been the result of a thorough review of the available scientific literature and a consensus process involving all members of the guideline group...
April 2018: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/29764832/large-bowel-obstruction-in-a-27-year-old-woman-caused-by-a-sigmoid-faecal-bolus
#14
Radford Arran James Smith, Muhammad Abdalkoddus, Robert Bethune
A 27-year-old woman presented to the emergency department with a 24-hour history of severe left iliac fossa pain associated with vomiting. She reported a history of ovarian cysts and was provisionally diagnosed with a ruptured ovarian cyst and admitted under the obstetrics and gynaecology team for further investigation. 24 hours later, she became haemodynamically unstable with increasing abdominal distention and developed a metabolic acidosis. A CT scan revealed large bowel obstruction (LBO) secondary to a faecal bolus in the sigmoid colon with appearances suggestive of adult-onset Hirschsprung's disease...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29763509/surgical-approach-to-hysterectomy-and-barriers-to-using-minimally-invasive-methods
#15
Monika Janda, Nigel R Armfield, Gayle Kerr, Suzanne Kurz, Graeme Jackson, Jason Currie, Katie Page, Edward Weaver, Anusch Yazdani, Andreas Obermair
Minimally invasive approaches to hysterectomy have been shown to be safe, effective and have recovery advantages over open hysterectomy, yet in Australia 36% of hysterectomies are still conducted by open surgery. In 2006, a survey of Australian gynaecological specialists found the main impediment to increasing laparoscopic hysterectomy to be a lack of surgical skills training opportunities. We resurveyed specialists to explore contemporary factors influencing surgeons' approaches to hysterectomy; 258 (estimated ~19%) provided analysable responses...
May 15, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29762551/a-pair-of-datasets-for-microrna-expression-profiling-to-examine-the-use-of-careful-study-design-for-assigning-arrays-to-samples
#16
Li-Xuan Qin, Huei-Chung Huang, Liliana Villafania, Magali Cavatore, Narciso Olvera, Douglas A Levine
We set out to demonstrate the logistic feasibility of careful experimental design for microarray studies and its level of scientific benefits for improving the accuracy and reproducibility of data inference. Towards this end, we conducted a study of microRNA expression using endometrioid endometrial tumours (n=96) and serous ovarian tumours (n=96) that were primary, untreated, and collected from 2000 to 2012 at Memorial Sloan Kettering Cancer Center. The same set of tumour tissue samples were profiled twice using the Agilent microRNA microarrays: once under an ideal experimental condition with balanced array-to-sample allocation and uniform handling; a second time by mimicking typical practice, with arrays assigned in the order of sample collection and processed by two technicians in multiple batches...
May 15, 2018: Scientific Data
https://www.readbyqxmd.com/read/29761478/pain-relief-for-women-undergoing-oocyte-retrieval-for-assisted-reproduction
#17
REVIEW
Irene Kwan, Rui Wang, Emily Pearce, Siladitya Bhattacharya
BACKGROUND: Various methods of conscious sedation and analgesia (CSA) have been used during oocyte retrieval for assisted reproduction. The choice of agent has been influenced by the quality of sedation and analgesia and by concerns about possible detrimental effects on reproductive outcomes. OBJECTIVES: To assess the effectiveness and safety of different methods of conscious sedation and analgesia for pain relief and pregnancy outcomes in women undergoing transvaginal oocyte retrieval...
May 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29757877/report-from-the-20th-meeting-of-the-european-society-of-gynaecological-oncology-esgo-2017
#18
Kamil Zalewski, Elisa Piovano, Zoia Razumova, Ilker Selcuk, Tanja Nikolova
This is a report from the 20th Meeting of the European Society of Gynaecological Oncology (ESGO) held in Vienna, Austria on November 4 to 7, 2017. The conference offered state-of-the-art educational sessions and oral and poster abstract presentations. The general sessions throughout the meeting focused not only on prevention, screening, diagnosis, treatment, and translational research but also emerging trends, and current innovations in gynecological cancers were discussed. The ESGO-European Society for Radiotherapy and Oncology-European Society of Pathology guidelines on management of cervical cancers were reported for the first time in public...
May 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29754478/methicillin-resistant-staphylococcus-aureus-contamination-of-phlebotomy-tourniquets-and-faucets
#19
T Abeywickrama, K Amarasinghe, S Wijerathne, C Dharmaratne, D Fernando, B C Senaratna, H A K M Gunasekera
Introduction: Methicillin resistant Staphylococcus aureus (MRSA) is transmitted through direct contact or fomites. The most important means of nosocomial spread is by hospital personnel. However, fomites are being increasingly recognized as sources of nosocomial infection. Objectives: Our aim was to describe the MRSA contamination rate of phlebotomy tourniquets and faucets in a tertiary care hospital and to compare the contamination of plastic tourniquets with that of fabric tourniquets...
March 31, 2018: Ceylon Medical Journal
https://www.readbyqxmd.com/read/29748194/clare-searle-combines-being-a-gp-with-obstetrics-and-gynaecology
#20
Anne Gulland
No abstract text is available yet for this article.
May 10, 2018: BMJ: British Medical Journal
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