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Drug abuse in women

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https://www.readbyqxmd.com/read/29792747/interpretation-time-using-a-concurrent-read-computer-aided-detection-system-for-automated-breast-ultrasound-in-breast-cancer-screening-of-women-with-dense-breast-tissue
#1
Yulei Jiang, Marc F Inciardi, Alexandra V Edwards, John Papaioannou
OBJECTIVE: The purpose of this study was to compare diagnostic accuracy and interpretation time of screening automated breast ultrasound (ABUS) for women with dense breast tissue without and with use of a recently U.S. Food and Drug Administration-approved computer-aided detection (CAD) system for concurrent read. MATERIALS AND METHODS: In a retrospective observer performance study, 18 radiologists interpreted a cancer-enriched set (i.e., cancer prevalence higher than in the original screening cohort) of 185 screening ABUS studies (52 with and 133 without breast cancer)...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29787580/risk-behaviors-and-hiv-care-continuum-outcomes-among-criminal-justice-involved-hiv-infected-transgender-women-and-cisgender-men-data-from-the-seek-test-treat-and-retain-harmonization-initiative
#2
Curt G Beckwith, Irene Kuo, Rob J Fredericksen, Lauren Brinkley-Rubinstein, William E Cunningham, Sandra A Springer, Kelsey B Loeliger, Julie Franks, Katerina Christopoulos, Jennifer Lorvick, Shoshana Y Kahana, Rebekah Young, David W Seal, Chad Zawitz, Joseph A Delaney, Heidi M Crane, Mary L Biggs
BACKGROUND: Transgender persons are highly victimized, marginalized, disproportionately experience incarceration, and have alarmingly increased rates of HIV infection compared to cis-gender persons. Few studies have examined the HIV care continuum outcomes among transgender women (TW), particularly TW who are involved with the criminal justice (CJ) system. METHODS: To improve our understanding of HIV care continuum outcomes and risk behaviors among HIV-infected TW who are involved with the CJ system, we analyzed data from the National Institute on Drug Abuse-supported Seek, Test, Treat, Retain (STTR) Data Harmonization Initiative...
2018: PloS One
https://www.readbyqxmd.com/read/29766147/the-non-preventive-effects-of-human-menopausal-gonadotropins-on-ovarian-tissues-in-nandrolone-decanoate-treated-female-rats-a-histochemical-and-ultra-structural-study
#3
Fakhroddin Mesbah, Hossein Bordbar, Tahereh Talaei Khozani, Farzaneh Dehghani, Hossein Mirkhani
Background: The follicular growth and development may be affected by abused drugs. Nandrolone decanoate (ND) as an anabolic androgenic steroid can damage the morphological and functional features of the ovary and may lead to reproductive failure. Objective: This study was designed to evaluate the effects of synchronized and non-synchronized administration of Human Menopausal Gonadotropins (hMG) with ND on ovarian tissue and level of sex hormones in the adult female rat...
March 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29761343/role-of-exogenous-progesterone-in-the-treatment-of-men-and-women-with-substance-use-disorders-a-narrative-review
#4
REVIEW
MacKenzie R Peltier, Mehmet Sofuoglu
Substance use disorders (SUDs) remain problematic as many individuals are untreated or do not benefit from the currently available interventions. Thus, there is an urgent need to develop novel pharmacological interventions to treat SUDs. Evidence suggests that the female sex hormone, progesterone, attenuates the craving for and the euphoric effects of drugs of abuse. Research to date has demonstrated that progesterone may modulate responses to drugs of abuse and may have utility as a novel treatment for SUDs...
May 14, 2018: CNS Drugs
https://www.readbyqxmd.com/read/29760674/validation-of-a-spanish-questionnaire-on-mobile-phone-abuse
#5
María A Olivencia-Carrión, Isabel Ramírez-Uclés, Pablo Holgado-Tello, Francisca López-Torrecillas
Mobile phone addiction has attracted much attention recently and is showing similarity to other substance use disorders. Because no studies on mobile phone addiction had yet been conducted in Spain, we developed and validated a questionnaire (Cuestionario de Abuso del Teléfono Móvil, ATeMo) to measure mobile phone abuse among young adults in Spanish. The ATeMo questionnaire was designed based on relevant DSM-5 diagnostic criteria and included craving as a diagnostic symptom. Using stratified sampling, the ATeMo questionnaire was administered to 856 students (mean age 21, 62% women)...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29694295/psychological-functioning-of-women-taking-illicit-drugs-during-pregnancy-and-the-growth-and-development-of-their-offspring-in-early-childhood
#6
Dana Serino, Bradley S Peterson, Tove S Rosen
OBJECTIVE: Assess psychosocial history and psychological functioning in women who use drugs during pregnancy and determine how drug exposure affects child development. METHODS: Pregnant marijuana (n = 38), cocaine (n = 35), methadone-maintained (n = 24), and control (n = 49) group women were enrolled and followed every 6 months through 18-24 months postnatally. RESULTS: There was a significantly higher incidence of mental illness in mothers in the drug groups...
April 25, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29693547/the-role-of-clinical-factors-in-the-association-of-gestational-diabetes-amongst-women-aged-15-49-years-residing-in-yazd-iran
#7
Mohammad Hasan Lotfi, Hossein Fallahzadeh, Masoud Rahmanian, Hossein Lashkardoost, Andishe Hamedi
BACKGROUND: Gestational diabetes mellitus (GDM) has occurred in Fourteen percent of all pregnancies in the world. Epidemiological evidences about risk factors of GDM may be different from region to region and are unknown, exactly. This study examines the role of clinical factors in the association of gestational diabetes in Yazd, Iran. METHODS: This study was carried out on 168 women with gestational diabetes and 168 women as controls after matching for age and place of residence...
April 16, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29687402/verbal-and-spatial-working-memory-among-drug-using-hiv-infected-men-and-women
#8
Eileen Martin, M K Keutmann, J S Fogel, P M Maki, R Gonzalez, J Vassileva, L H Rubin, D Hardy
Working memory (WM) is a critical component of many neurocognitive functions. The literature has demonstrated consistently that WM impairment is more frequent and severe among substance-dependent individuals (SDIs) infected with HIV compared with uninfected SDIs; however, the SDIs who participated in these previous studies were primarily male. There are few published data on WM performance among HIV+ women with or without substance use disorders, and essentially no direct comparisons of WM performance between HIV+ men and women, regardless of substance use...
April 23, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29672167/sex-differences-in-opioid-use-and-medical-issues-during-buprenorphine-naloxone-treatment
#9
Celestina Barbosa-Leiker, Sterling McPherson, Matthew E Layton, Ekaterina Burduli, John M Roll, Walter Ling
BACKGROUND: There are sex differences in buprenorphine/naloxone clinical trials for opioid use. While women have fewer opioid-positive urine samples, relative to men, a significant decrease in opioid-positive samples was found during treatment for men, but not women. In order to inform sex-based approaches to improve treatment outcomes, research is needed to determine if opioid use, and predictors of opioid use, differs between men and women during treatment. OBJECTIVES: To test for sex differences in opioid use during a buprenorphine/naloxone clinical trial and determine if sex differences exist in the associations between addiction-related problem areas and opioid use over the course of the trial...
April 19, 2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29657695/effectiveness-of-transactional-analysis-group-therapy-on-addiction-intensity-of-woman-patients-treated-with-methadone
#10
Niloofar Etemadi-Chardah, Bahman Matinpour, Rasoul Heshmati
Background: Addiction brings about severe and profound physical, psychological and social damages such as divorce, crime, and unemployment. The present study was to investigate the effectiveness of transactional analysis (TA) therapy on addiction intensity of woman patients treated with methadone. Methods: The research design was quasi-experimental with a pretest-posttest and a control group. The statistical population consisted of all the addicted women who referred to any drug rehabilitation center of Tehran, Iran, in 2016...
July 2017: Addiction & Health
https://www.readbyqxmd.com/read/29653137/hyperactivity-and-memory-learning-deficits-evoked-by-developmental-exposure-to-nicotine-and-or-ethanol-are-mitigated-by-camp-and-cgmp-signaling-cascades-activation
#11
Yael Abreu-Villaça, Anna C Carvalho-Graça, Gabriela Skinner, Bruna M Lotufo, Vitor H S Duarte-Pinheiro, Anderson Ribeiro-Carvalho, Alex C Manhães, Claudio C Filgueiras
Pregnant smoking women are frequently episodic drinkers. Here, we investigated whether ethanol exposure restricted to the brain growth spurt period when combined with chronic developmental exposure to nicotine aggravates memory/learning deficits and hyperactivity, and associated cAMP and cGMP signaling disruption. To further investigate the role of these signaling cascades, we verified whether vinpocetine (a phosphodiesterase inhibitor) ameliorates the neurochemical and behavioral outcomes. Swiss mice had free access to nicotine (NIC, 50 μg/ml) or water to drink during gestation and until the 8th postnatal day (PN8)...
April 10, 2018: Neurotoxicology
https://www.readbyqxmd.com/read/29651922/prior-exposure-to-intimate-partner-violence-associated-with-less-hiv-testing-among-young-women
#12
Yukiko Washio, Elizabeth Novack Wright, Annet Davis-Vogel, Jesse Chittams, Claire Anagnostopulos, Linda M Kilby, Anne M Teitelman
Low-income minority women are disproportionately represented among those living with HIV in the United States. They are also at risk for the SAVA (substance abuse, violence, and HIV/AIDS) syndemic issues. Women who have recently given birth are at high risk for substance use and intimate partner violence (IPV), and HIV testing is not routinely administered during the postpartum visit. We explored the relationship between substance use, IPV, and HIV testing among low-income young adult women attending Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), a federally supported nutrition program...
April 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29651200/return-to-illicit-drug-use-post-incarceration-among-formerly-incarcerated-black-americans
#13
Tawandra L Rowell-Cunsolo, Betsy Szeto, Charlotte McDonald, Nabila El-Bassel
Aims: The number of drug dependent individuals incarcerated in the U.S. is exceptionally high, and reportedly 60 percent of incarcerated Black Americans have a substance abuse disorder. The purpose of this study was to identify factors associated with return to illicit drug use post-incarceration. Methods: A cross-sectional study was conducted with 121 formerly incarcerated Black Americans in New York City to examine predictors of return to illicit drug use. Kaplan-Meier curves were generated on the outcome of time-to-drug use for various predictors and compared using the log-rank test...
2018: Drugs: Education, Prevention, and Policy
https://www.readbyqxmd.com/read/29621962/maternal-hair-and-neonatal-meconium-to-assess-gestational-consumption-and-prenatal-exposure-to-drugs-of-abuse-and-psychoactive-drugs
#14
Francesco Paolo Busardo, Laura Almeida, Laura Cortes, Sally Sabraa, Marta Muniesaa, Oscar Garcia-Algara, Maria Dolores Gomez-Roiga
BACKGROUND: In the last two decades, the consumption of drugs of abuse among women of childbearing age has experienced a significant increase and results from analyses of surveys concerning maternal intake of psychoactive prescription drugs during pregnancy indicate that the rates of intake are increasing each year. Analyses of biological matrices such as maternal hair and neonatal meconium have recently been used for assessment of gestational consumption and consequent prenatal exposure to drugs of abuse in high-risk groups of women METHODS: Maternal hair and neonatal meconium were analyzed by validated chromatographic mass spectrometric methodologies to disclose gestational use of drugs of abuse and psychoactive prescription drugs and consequent prenatal exposure in a cohort of 513 mother-newborn dyads at the Sant Joan de Déu Barcelona Hospital, Spain, during 2012- 2013...
April 5, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29609675/injury-and-psychiatric-disorder-in-low-income-women-experiencing-bidirectional-intimate-partner-violence
#15
Monic P Behnken, Yinghui Duan, Jeff R Temple, Zhao Helen Wu
This study compared severity of physical violence, intimate partner violence (IPV)-related injury, and lifetime diagnoses of psychiatric disorders among women in relationships with bidirectional, unidirectional, or no IPV. The sample includes 763 low-income women from community-based family planning clinics. Results showed that women in relationships with bidirectional IPV were more likely to experience severe physical violence and severe IPV-related injury compared to women in the unidirectional IPV category...
April 1, 2018: Violence and Victims
https://www.readbyqxmd.com/read/29600412/associations-of-monoamine-oxidase-a-gene-first-exon-methylation-with-sexual-abuse-and-current-depression-in-women
#16
David Checknita, Tomas J Ekström, Erika Comasco, Kent W Nilsson, Jari Tiihonen, Sheilagh Hodgins
Childhood physical abuse (PA) and sexual abuse (SA) interact with monoamine oxidase A (MAOA) gene polymorphism to modify risk for mental disorders. In addition, PA and SA may alter gene activity through epigenetic mechanisms such as DNA methylation, thereby further modifying risk for disorders. We investigated whether methylation in a region spanning the MAOA first exon and part of the first intron was associated with PA and/or SA, MAOA genotype, alcohol dependence, drug dependence, depression disorders, anxiety disorders, and conduct disorder...
March 29, 2018: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29578830/mortality-and-cause-of-death-a-30-year-follow-up-of-substance-misusers-in-sweden
#17
Ninive von Greiff, Lisa Skogens, Marie Berlin, Anders Bergmark
BACKGROUND: This article presents a 30-year follow-up study of a cohort of 1163 substance misusers who were in inpatient treatment in the early 1980s. Data was originally collected in the Swedish Drug Addict Treatment Evaluation (SWEDATE). OBJECTIVES: The aim is to examine the overall mortality and identify causes of death in different groups based on self-reported most dominant substance misuse among those who have died during January 1984-December 2013. METHODS: SWEDATE-data was linked to the National Cause of Death Register...
March 26, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29575867/pregnancy-planning-and-risk-behaviours-a-survey-of-women-s-experiences-in-selected-european-countries
#18
Małgorzata Lesińska-Sawicka, Małgorzata Nagórska
Pregnancy, a special period in a woman's life, should be preceded by proper preparation: a positive attitude to procreation, selection of optimum time for becoming pregnant, starting prevention of neural tube defects, restriction of the use of drugs, smoking, etc. The aim of this study was to determine the effect of pregnancy planning and antenatal classes on the use of stimulants during pregnancy. The study group included 877 women living in 7 European countries, and their experiences of planning pregnancy and substance abuse during pregnancy were investigated...
March 14, 2018: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29560840/older-women-who-died-by-suicide-suicide-means-sociodemographic-and-psychiatric-risk-factors-and-other-precipitating-circumstances
#19
Namkee G Choi, Diana M DiNitto, Atami O Sagna, C Nathan Marti
BACKGROUND: US suicide rates among older women have substantially increased over the past decade. We examined potential differences in sociodemographic and risk/precipitating factors among older female suicide decedents who died by drug overdose versus firearms, hanging/suffocation, and other means, and postmortem toxicology results by suicide means. METHODS: Data are from the 2005 to 2015 US National Violent Death Reporting System (N = 12,401 female decedents aged 50 years and over)...
March 21, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29549390/ethanol-actions-on-the-ventral-tegmental-area-novel-potential-targets-on-reward-pathway-neurons
#20
REVIEW
Chang You, Bertha Vandegrift, Mark S Brodie
The ventral tegmental area (VTA) evaluates salience of environmental stimuli and provides dopaminergic innervation to many brain areas affected by acute and chronic ethanol exposure. While primarily associated with rewarding and reinforcing stimuli, recent evidence indicates a role for the VTA in aversion as well. Ethanol actions in the VTA may trigger neuroadaptation resulting in reduction of the aversive responses to alcohol and a relative increase in the rewarding responses. In searching for effective pharmacotherapies for the treatment of alcohol abuse and alcoholism, recognition of this imbalance may reveal novel strategies...
June 2018: Psychopharmacology
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