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Drug abuse in women

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https://www.readbyqxmd.com/read/29153668/outcomes-and-mortality-in-parturient-and-non-parturient-patients-with-peripartum-cardiomyopathy-a-national-readmission-database-study
#1
Nisha Chhabra, Atul Gupta, Rachna Chibber, Mohammed Minhaj, Jennifer Hofer, Ariel Mueller, Avery Tung, Michael O'Connor, Barbara Scavone, Sarosh Rana, Sajid Shahul
BACKGROUND: Peripartum cardiomyopathy (PPCM) affects young females and mortality occurs after the peripartum period. Hospital readmissions for patients discharged with PPCM are poorly understood. The aim of this study was to evaluate differences in readmission rates, risk factors, and mortality in women with PPCM. METHODS: We conducted a retrospective cohort analysis using the Healthcare Cost and Utilization Project 2013 National Readmissions Database. From the database, we selected patients with PPCM to include patients discharged between January and November 2013...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29142909/transgender-women-s-drug-use-in-the-dominican-republic
#2
Henna Budhwani, Kristine R Hearld, Adrienne N Milner, Elaine McGlaughlin, Rebecca Charow, Rosa Mayra Rodriguez-Lauzurique, Santo Rosario, Robert Paulino-Ramirez
Purpose: Studies on drug use in transgender populations, particularly those in resource-limited settings, are scarce. Considering that drug use can be a coping mechanism to deal with stigma and traumatic experiences, we examined associations between stigma, trauma, and drug use in a national sample of transgender women from the Dominican Republic. Methods: Bivariate analyses examined differences between drug users and abstainers (n=287). Multivariate analyses reported odds ratios (OR) with general drug, marijuana, and cocaine use as outcomes (n=243)...
2017: Transgender Health
https://www.readbyqxmd.com/read/29131068/maternal-cannabinoid-use-alters-cannabinoid-cb1-and-endothelin-etb-receptor-expression-in-the-brains-of-dams-but-not-their-offspring
#3
Aarti Amlani, Mary G Hornick, Kevin Cooper, Preetha Prazad, Ramona Donovan, Anil Gulati
According to the 2015 National Survey on Drug Use and Health, cannabis (marijuana) is the most commonly used recreational drug in the US. Among pregnant women aged 14-55 years, 3.4% were cannabis users. Presently, little is known about the neurodevelopmental effect of cannabis use during pregnancy and/or nursing on neonates. Endothelin (ET) is essential for normal development of the central nervous system (CNS). Decreases in ETB receptor expression correlate with a decline in nerve growth factor (NGF) and an increase in vascular endothelial growth factor (VEGF) in postnatal brain...
November 4, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/29117747/substance-use-among-danish-psychiatric-patients-a-cross-sectional-study
#4
Tina Sørensen, Hans Søe Riis Jespersen, Maj Vinberg, Ulrik Becker, Ola Ekholm, Anders Fink-Jensen
BACKGROUND: Patients with psychiatric disorders have a greater risk of mortality than the general population. Use or abuse of substances, including alcohol, play a crucial part in this context. Moreover, it is well known that drug use can worsen psychopathology and reduce treatment compliance. However, the magnitude of these problems among Danish psychiatric patients has not been studied previously. AIMS: The aim of this study is to investigate substance use among psychiatric patients in the Capital Region of Denmark...
November 9, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29070156/born-into-addiction-neonatal-abstinence-syndrome-and-pediatric-dentistry
#5
Jennifer L Cully
Drug overdose and opioid-involved deaths continue to increase across the United States. An end-condition related to opioid abuse is neonatal abstinence syndrome (NAS). The implications for pregnant or post-partum women using an opioid, whether prescribed or illicit, can have significant effects on their infant. First described in the 1970s, NAS is defined as a postnatal drug withdrawal syndrome that primarily occurs in opioid-exposed infants. There are no nationally accepted, evidence-based treatment protocols for these infants...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29070078/prevalence-of-prenatal-exposure-to-substances-of-abuse-questionnaire-versus-biomarkers
#6
REVIEW
Antonella Chiandetti, Gimena Hernandez, María Mercadal-Hally, Airam Alvarez, Vicente Andreu-Fernandez, Elisabet Navarro-Tapia, Adriana Bastons-Compta, Oscar Garcia-Algar
Alcohol and drugs of abuse consumption in young adults, including women of childbearing age, has experienced significant increase over the past two decades. The use of questionnaires as the only measure to investigate prenatal alcohol and drugs of abuse exposure underestimates the real prevalence of exposure and could mislead to wrong conclusions. Therefore, the aim of this article was to compare reported rates of prenatal alcohol and drugs of abuse consumption with biomarkers of exposure by a comprehensive review of the available literature...
October 25, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29069102/enduring-impact-of-conflict-on-mental-health-and-gender-based-violence-perpetration-in-bougainville-papua-new-guinea-a-cross-sectional-study
#7
Rachel Jewkes, Nwabisa Jama-Shai, Yandisa Sikweyiya
BACKGROUND: Violence against women is often exacerbated by war, but most civilian research has investigated short term impact. We describe the conflict experiences of men and women from the general population of Bougainville Papua New Guinea, perceptions of the enduring impact of conflict, and the associations between these and the major health and development problems on the islands: mental ill-health and violence against women. METHODS: Fourteen years after the end of the decade long civil war, we conducted a household survey with a random sample of adult (n = 864) men and (n = 879) women living in Bougainville...
2017: PloS One
https://www.readbyqxmd.com/read/29055748/sex-and-dose-dependent-abuse-liability-of-repeated-subanesthetic-ketamine-in-rats
#8
Kristin J Schoepfer, Caroline E Strong, Samantha K Saland, Katherine N Wright, Mohamed Kabbaj
RATIONALE: Subanesthetic ketamine (KET) elicits rapid, robust, but transient antidepressant effects. KET's antidepressant actions can be augmented and maintained for a longer duration when repeatedly delivered. However, KET is recreationally abused, raising long-term treatment safety concerns. Women are more likely than men to seek treatment for depression, escalate from casual to compulsive drug use, and are more sensitive to antidepressants. Similarly, female rodents are more sensitive than males to KET's rapid antidepressant-like behavioral effects; dose-response thresholds in these assays equal 2...
October 18, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29055747/sex-differences-in-prenatal-stress-effects-on-cocaine-pursuit-in-rats
#9
Mark B Thomas, Jill B Becker
Disruption of early-life ontogeny has severe and persistent consequences for the health of the developing organism. Both clinical and preclinical findings indicate that such interference can be caused by maternal stress during the gestation period (prenatal stress [PS]). In rats, PS facilitates the rewarding and neurochemical-stimulating effects of drugs, suggesting that PS may represent a risk factor for drug abuse in humans. Very little, however, is known about its effects in females, even though sex differences in drug susceptibility have been well documented in no PS (NPS) controls...
October 18, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29040840/experiences-of-structural-vulnerability-among-exotic-dancers-in-baltimore-maryland-co-occurring-social-and-economic-antecedents-of-hiv-sti-risk
#10
Meredith L Brantley, Katherine H A Footer, Sahnah Lim, Deanna Kerrigan, Susan G Sherman
BACKGROUND: Women who grow up in economic scarcity often face limited opportunities for upward mobility, as a result of challenges securing stable housing, quality education, and steady employment. Chronic instability may limit the capacity of women to protect themselves against HIV/STI-related harm when engaging in sexual activity or drug use. Characterizing the structural contexts that facilitate HIV/STI risk among women are critical to effective design and implementation of drug and sexual harm reduction interventions...
October 14, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29035155/effects-of-social-and-spatial-contexts-on-young-latinas-methamphetamine-use-initiation
#11
Ann M Cheney, Christine N Newkirk, Vhuhwavho M Nekhavhambe, Matthew Baron Rotondi, Alison Hamilton
In this article, we examine methamphetamine (meth) use initiation as influenced by Latinas' social positions within institutions (e.g., family and economy). We conducted ethnographic fieldwork in five women's residential substance use treatment facilities in Los Angeles County with women who considered meth to be their primary drug of choice. Using an urban ethnographic framing, we demonstrate the effects of low-income young Latinas' spatial- and social-context rendered vulnerability to abuse and neglect, and the resulting emotional distress, on meth use initiation...
October 16, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29032350/identifying-characteristics-of-the-most-severely-impaired-chronic-pain-patients-treated-at-a-specialized-inpatient-pain-clinic
#12
Eva-Britt Hysing, Lena Smith, Mans Thulin, Rolf Karlsten, Stephen Butler, Torsten Gordh
BACKGROUND AND AIMS: Patients suffering from chronic nonmalignant pain constitute a heterogeneous population in terms of clinical presentation and treatment results. Few data are available about what distinguishes different groups in this huge population of patients with chronic persistent pain (CPP). A subgroup that is poorly studied, consists of the most severely impaired chronic pain patients. At the Uppsala University Hospital Pain Clinic, there is a specialized department accepting the most complex patients for rehabilitation...
October 12, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29022077/no-association-between-periodontitis-and-preterm-low-birth-weight-a-case-control-study
#13
Mariana Fampa Fogacci, Elaine de O C Cardoso, Davi da S Barbirato, Denise Pires de Carvalho, Carmelo Sansone
PURPOSE: This study aimed to investigate the association between periodontitis in pregnant women and adverse pregnancy outcomes by heeding confounding risk factors for preterm low birth weight infants. METHODS: This study was reported according to The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement. A case-control study was conducted. Medical records of all pregnant women attending a prenatal care clinic were screened. Those between 21 and 34 years and gestational age of 28-32 weeks were initially enrolled in the study...
October 11, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29021359/increasing-prevalence-of-vascular-risk-factors-in-patients-with-stroke-a-call-to-action
#14
Fadar Oliver Otite, Nicholas Liaw, Priyank Khandelwal, Amer M Malik, Jose G Romano, Tatjana Rundek, Ralph L Sacco, Seemant Chaturvedi
OBJECTIVE: To evaluate trends in prevalence of cardiovascular risk factors (hypertension, diabetes, dyslipidemia, smoking, and drug abuse) and cardiovascular diseases (carotid stenosis, chronic renal failure [CRF], and coronary artery disease [CAD]) in acute ischemic stroke (AIS) in the United States. METHODS: We used the 2004-2014 National Inpatient Sample to compute weighted prevalence of each risk factor in hospitalized patients with AIS and used joinpoint regression to evaluate change in prevalence over time...
November 7, 2017: Neurology
https://www.readbyqxmd.com/read/28983558/association-between-opioid-prescribing-patterns-and-abuse-in-ophthalmology
#15
Shriji Patel, Paul Sternberg
Importance: Drug overdoses have become the number 1 cause of mortality in American adults 50 years and younger. Prescription opioid abuse is a growing concern that has garnered widespread attention among policymakers and the general public. Objective: To determine the opioid prescribing patterns among ophthalmologists and elucidate their role in the prescription opioid abuse epidemic. Design, Setting, and Participants: In this observational cohort study, beneficiaries and their physicians were analyzed using 2013 to 2015 Medicare Part D Prescriber Data...
November 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28979994/factors-associated-with-30-day-readmission-after-primary-total-hip-arthroplasty-analysis-of-514%C3%A2-455-procedures-in-the-uk-national-health-service
#16
Adam M Ali, Mark D Loeffler, Paul Aylin, Alex Bottle
Importance: Thirty-day readmission to hospital after total hip arthroplasty (THA) has significant direct costs and is used as a marker of hospital performance. All-cause readmission is the only metric in current use, and risk factors for surgical readmission and those resulting in return to theater (RTT) are poorly understood. Objective: To determine whether patient-related predictors of all-cause, surgical, and RTT readmission after THA differ and which predictors are most significant...
October 4, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28954143/childhood-and-adolescent-sexual-abuse-victim-profile-and-its-impacts-on-mental-health
#17
Luiz Felipe Campos Fontes, Otavio Canozzi Conceição, Sthefano Machado
This work aims to analyze the impact of childhood and adolescent sexual abuse on variables related to mental health and to identify the characteristics of the victims. To achieve this objective, microdata of the National School Health Survey 2015 was used, applying the methodology of Propensity Score Matching. The results show that the abused youth has a unique behavioral, familiar and socioeconomic profile and that they are more likely to use alcohol and drugs, be victim of bullying, to be in age-grade lag, to be employed and not to intend to continue studying...
September 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28950402/transgender-women-s-experiences-with-stigma-trauma-and-attempted-suicide-in-the-dominican-republic
#18
Henna Budhwani, Kristine R Hearld, Adrienne N Milner, Rebecca Charow, Elaine M McGlaughlin, Mayra Rodriguez-Lauzurique, Santo Rosario, Robert Paulino-Ramirez
Studies on attempted suicide in transgender populations, particularly those in resource-limited settings, are scarce. We examined the relationships between stigma, trauma, and suicide attempts in a national sample of transgender women from the Dominican Republic. Bivariate analysis examined differences between suicide attempters and nonattempters (n = 298). Multivariate analysis reported odds ratios with attempted suicide as the outcome (n = 260). About a quarter of respondents (23.9%) experienced sexual abuse, 12...
September 26, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28940428/maternal-alcohol-use-and-nutrition-during-pregnancy-diet-and-anthropometry
#19
R Colin Carter, Marjanne Senekal, Neil C Dodge, Lori Bechard, Ernesta M Meintjes, Christopher D Molteno, Christopher Duggan, Joseph L Jacobson, Sandra W Jacobson
BACKGROUND: Despite known risks of prenatal nutritional deficiencies and studies documenting increased prevalence of poor dietary intake among non-pregnant alcohol abusers, the nutritional status of heavy drinking pregnant women remains largely unstudied. Animal models have found interactions between prenatal ethanol exposure and micronutrients, such as choline, folate, B12, and iron, and human studies have reported that lower maternal weight and body mass confer increased fetal alcohol-related risk...
September 20, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28939573/does-psychedelic-drug-use-reduce-risk-of-suicidality-evidence-from-a-longitudinal-community-based-cohort-of-marginalised-women-in-a-canadian-setting
#20
Elena Argento, Steffanie A Strathdee, Kenneth Tupper, Melissa Braschel, Evan Wood, Kate Shannon
OBJECTIVE: This study aimed to longitudinally investigate whether ever having used a psychedelic drug can have a protective effect on incidence of suicidality among marginalised women. DESIGN: Longitudinal community-based cohort study. SETTING: Data were drawn from a prospective, community-based cohort of marginalised women in Metro Vancouver, Canada. PARTICIPANTS: 766 women completed the baseline questionnaire between January 2010 and August 2014...
September 21, 2017: BMJ Open
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