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https://www.readbyqxmd.com/read/29118769/clinical-usefulness-of-urinary-liver-fatty-acid-binding-protein-excretion-for-predicting-acute-kidney-injury-during-the-first-7-days-and-the-short-term-prognosis-in-acute-heart-failure-patients-with-non-chronic-kidney-disease
#1
Akihiro Shirakabe, Noritake Hata, Nobuaki Kobayashi, Hirotake Okazaki, Masato Matsushita, Yusaku Shibata, Suguru Nishigoori, Saori Uchiyama, Kuniya Asai, Wataru Shimizu
Background: The clinical significance of urinary liver fatty acid-binding protein (u-LFABP) in acute heart failure (AHF) patients remains unclear. Methods and Results: The u-LFABP levels on admission of 293 AHF patients were analyzed. The patients were divided into 2 groups according to the u-LFABP quartiles (Q1, Q2, and Q3 = low u-LFABP [L] group vs. Q4 = high u-LFABP [H] group). We evaluated the diagnostic and prognostic value of u-LFABP and compared the findings between the chronic kidney disease (CKD; n = 165) and non-CKD patients (n = 128)...
October 2017: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29092921/contrast-induced-acute-kidney-injury-and-mortality-in-st-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention
#2
Johanne Silvain, Lee S Nguyen, Vincent Spagnoli, Mathieu Kerneis, Paul Guedeney, Nicolas Vignolles, Kristel Cosker, Olivier Barthelemy, Claude Le Feuvre, Gérard Helft, Jean-Philippe Collet, Gilles Montalescot
OBJECTIVES: Contrast-induced acute kidney injury (CI-AKI) is a common and potentially severe complication in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). There is no consensus on the best definition of CI-AKI to identify patients at risk of haemodialysis or death. The objective of this study was to assess the association of CI-AKI, using four definitions, on inhospital mortality, mortality or haemodialysis requirement over 1-year follow-up, in patients with STEMI treated with pPCI...
November 1, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29091905/the-effect-of-range-and-ammunition-type-on-fracture-patterns-in-porcine-postcranial-flat-bones
#3
Kleio Fragkouli, Eyad Al Hakeem, Ozgur Bulut, Tal Simmons
Pig half-carcasses were shot in scapulae, ribs and mandibles with either 0.243 hunting rifle using high velocity expanding ammunition (N = 30) or AK47 using full metal jacketed (FMJ) ammunition (N = 12) from a range of either 5 or 20 m. Fracture patterns related to distance of fire and ammunition type were compared on de-fleshed, macerated, and reconstructed bones. For expanding ammunition, location of fracture on ribs affected the resulting pattern. Scapulae shot from 5 m presented a comminuted pattern different from those shot from 20 m...
October 5, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29079062/correlation-between-resting-state-electroencephalographic-characteristics-and-shooting-performance
#4
Anmin Gong, Jianping Liu, Fangbo Li, Fangyi Liu, Changhao Jiang, Yunfa Fu
According to the theories of neural plasticity and neural efficiency, professional skill training improves performance by strengthening the underlying neural mechanisms. Therefore, subjects trained professionally may exhibit changes in resting-state neurophysiological characteristics closely related to performance. To test this notion, the resting-state electroencephalogram (EEG) was measured from 35 rifle shooters after the same training regimen, and resting-state EEG characteristics were analyzed for correlations with shooting performance...
October 25, 2017: Neuroscience
https://www.readbyqxmd.com/read/29045467/the-dose-of-hydroxyethyl-starch-6-130-0-4-for-fluid-therapy-and-the-incidence-of-acute-kidney-injury-after-cardiac-surgery-a-retrospective-matched-study
#5
Mona Momeni, Lompoli Nkoy Ena, Michel Van Dyck, Amine Matta, David Kahn, Dominique Thiry, André Grégoire, Christine Watremez
The safety of hydroxyethyl starches (HES) is still under debate. No studies have compared different dosing regimens of HES in cardiac surgery. We analyzed whether the incidence of Acute Kidney Injury (AKI) differed taking into account a weight-adjusted cumulative dose of HES 6% 130/0.4 for perioperative fluid therapy. This retrospective cohort study included all adult patients undergoing elective or emergency cardiac surgery with or without cardiopulmonary bypass. Exclusion criteria were patients on renal replacement therapy (RRT), cardiac trauma surgery, heart transplantation, patients with ventricular assist devices, subjects who required a surgical revision for bleeding and those whose medical records were incomplete...
2017: PloS One
https://www.readbyqxmd.com/read/29038262/severe-infusion-related-adverse-events-and-renal-failure-in-patients-receiving-high-dose-intravenous-polymyxin-b
#6
Josiane F John, Diego R Falci, Maria Helena Rigatto, Renata D Oliveira, Thaysa G Kremer, Alexandre P Zavascki
Very high doses of polymyxin B (PMB) have been addressed in in vitro experiments against carbapenem-resistant Gram-negative bacilli as a strategy to improve bacterial killing and suppress resistance emergence. However, the toxicities of very high doses in patients are unknown. This is a retrospective cohort study assessing patients receiving >3mg/kg/day or a total dose ≥250mg/day of PMB. The main outcomes were severe infusion-related adverse event according to Common Terminology Criteria for Adverse Criteria and renal failure category of RIFLE criteria for acute kidney injury (AKI) during treatment...
October 16, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29026261/prevention-of-noise-induced-hearing-loss-from-recreational-firearms
#7
REVIEW
Deanna K Meinke, Donald S Finan, Gregory A Flamme, William J Murphy, Michael Stewart, James E Lankford, Stephen Tasko
In the United States and other parts of the world, recreational firearm shooting is a popular sport that puts the hearing of the shooter at risk. Peak sound pressure levels (SPLs) from firearms range from ∼140 to 175 dB. The majority of recreational firearms (excluding small-caliber 0.17 and 0.22 rifles and air rifles) generate between 150 and 165 dB peak SPLs. High-intensity impulse sounds will permanently damage delicate cochlear structures, and thus individuals who shoot firearms are at a higher risk of bilateral, high-frequency, noise-induced hearing loss (NIHL) than peer groups who do not shoot...
November 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28984058/multivariate-analysis-of-risk-factors-for-cisplatin-induced-nephrotoxicity-in-gynecological-cancer
#8
Yoshihiro Yamamoto, Kazushi Watanabe, Hiroshi Matsushita, Ikuto Tsukiyama, Katsuhiko Matsuura, Akihiko Wakatsuki
AIM: Risk factors for cisplatin-induced nephrotoxicity (CIN) vary by population. This study aimed to assess risk factors for CIN in patients with gynecological cancer. METHODS: Patients who underwent cisplatin-based chemotherapy for gynecological cancer between January 2009 and December 2015 at Aichi Medical University School of Medicine were included in this study. CIN was defined according to the 'risk, injury, failure, loss, and end-stage kidney disease' (RIFLE) criteria and classified as either risk (Class R) or injury (Class I)...
October 6, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28980553/-determination-of-the-barrel-inclination-of-the-ak-74-assault-rifle-from-the-specific-features-of-soot-deposition-after-a-shot-around-the-inlet-wounds-caused-by-a-burst-of-shots
#9
A A Gusarov, I Yu Makarov, V A Fetisov
The specific features of soot deposition after a shot fired from the Kalashnikov AK-74 assault rifle are determined by the influence of the multiple factors, with the effect of the muzzle brake (MB) designed to enhance fire density and decrease the fire recoil energy being prevalent over other factors. The special windows, slots and holes in the muzzle brake mechanism are responsible for the appearance of the specific topographic features of soot deposition formed by the combustion gases passing through the assembly...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28980546/-the-possibility-of-using-the-synthetic-compound-for-the-purpose-of-modeling-of-the-human-soft-tissues-in-connection-with-the-evaluation-of-gunshot-damages
#10
I V Latyshov, V A Vasil'ev, I V Zaporotskova, T A Ermakova
The necessity of using a simulator of human soft tissues for the purpose of criminalistic and forensic medical expertises is dictated by the requirements put forward by the expert practice. The objective of the present study was to develop a synthetic simulator of the human soft tissues (compound) to ensure reliability of comparative criminalistics and forensic medical studies for the evaluation of gunshot injuries. The synthetic compound was prepared by mixing up the petroleum and/or synthetic oil with a polymeric thickening agent...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28979332/nephrotoxicity-of-high-and-conventional-dosing-regimens-of-colistin-a-randomized-clinical-trial
#11
Atefeh Ordooei Javan, Shervin Shokouhi, Zahra Sahraei, Jamshid Salamzadeh, Saeed Azad Armaki
Nephrotoxicity has been a major long-standing concern about colistin.This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin. A randomized open-labeled clinical trial on 40 patients with multi-drug resistant gram negative infections was designed. Patients were allocated into two equal-size groups receiving high (a loading dose of 9 million international units (MIU) and maintenance doses of 4.5 MIU every 12 h) and conventional dose (2 MIU every 8 h) of colistin. Blood samples were taken on day 1, 3, 5, 7 and 10 of treatment for measuring serum cystatin C (Cys C) levels...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28971349/criminal-use-of-assault-weapons-and-high-capacity-semiautomatic-firearms-an-updated-examination-of-local-and-national-sources
#12
Christopher S Koper, William D Johnson, Jordan L Nichols, Ambrozine Ayers, Natalie Mullins
Policies restricting semiautomatic assault weapons and large-capacity ammunition magazines are intended to reduce gunshot victimizations by limiting the stock of semiautomatic firearms with large ammunition capacities and other military-style features conducive to criminal use. The federal government banned such weaponry from 1994 to 2004, and a few states currently impose similar restrictions. Recent debates concerning these weapons have highlighted their use in mass shootings, but there has been little examination of their use in gun crime more generally since the expiration of the federal ban...
October 2, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28964618/long-term-fate-of-renal-function-after-open-surgery-for-juxtarenal-and-pararenal-aortic-aneurysm
#13
Masayuki Sugimoto, Noriko Takahashi, Kiyoaki Niimi, Akio Kodama, Hiroshi Banno, Kimihiro Komori
BACKGROUND: Although the indications for endovascular aneurysm repair for abdominal aortic aneurysm have been expanding, our primary strategy for pararenal and juxtarenal abdominal aortic aneurysm (P/JRAA) is open surgery (OS). One consequence of OS for P/JRAA is transient renal ischemia owing to renal artery clamping, which can be followed by acute kidney injury (AKI). Prior studies referred to the impact of renal ischemia on AKI, but they have rarely evaluated longer-term renal function...
September 27, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28956324/treatment-with-allopurinol-is-associated-with-lower-risk-of-acute-kidney-injury-in-patients-with-gout-a-retrospective-analysis-of-a-nested-cohort
#14
Fernando Perez-Ruiz
INTRODUCTION: Gout is characterized by recurrent episodes of acute inflammation of joint structures, called gout flares, and flares are commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs). The objective of the study was to evaluate risk factors associated with acute kidney injury (AKI) attributed to NSAIDs in a cohort of patients who were exposed to NSAIDs to treat gout flares prior to urate-lowering therapy. METHODS: Retrospective analysis of a nested cohort of 983 gout patients in whom general variables (age, gender, renal function, ethanol intake, hypertension, hyperlipidemia, diabetes, vascular events, diuretic use) and also variables related to gout and severity of gout (serum urate levels, number for flares per year, presence of tophi, joint distribution, X-ray involvement, previous urate-lowering therapy) were available for analysis...
September 27, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28919792/clinical-outcomes-and-nephrotoxicity-of-colistin-loading-dose-for-treatment-of-extensively-drug-resistant-acinetobacter-baumannii-in-cancer-patients
#15
Wasan Katip, Suriyon Uitrakul, Peninnah Oberdorfer
BACKGROUND: Colistin is a last-line defense therapy against extensively drug-resistant Acinetobacter baumannii (XDR-AB). Despite a loading dose of colistin being applied in many clinical practices, studies evaluating the effect of the loading dose of colistin in cancer patients remain limited. PATIENTS AND METHODS: A retrospective cohort study of cancer patients who received either a loading or non-loading dose of colistin for treatment of XDR-AB was conducted. For each group, the clinical response, bacteriological eradication and serum creatinine were recorded...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28874330/comparison-of-rifle-akin-and-kdigo-classifications-for-assessing-prognosis-of-patients-on-extracorporeal-membrane-oxygenation
#16
Tsung-Yu Tsai, Hao Chien, Feng-Chun Tsai, Heng-Chih Pan, Huang-Yu Yang, Shen-Yang Lee, Hsiang-Hao Hsu, Ji-Tseng Fang, Chih-Wei Yang, Yung-Chang Chen
BACKGROUND/PURPOSE: Acute kidney injury (AKI) developing during extracorporeal membrane oxygenation (ECMO) is associated with very poor outcome. The Kidney Disease: Improving Global Outcomes (KDIGO) group published a new AKI definition in 2012. This study analyzed the outcomes of patients treated with ECMO and identified the relationship between the prognosis and the KDIGO classification. METHODS: This study examined total 312 patients initially, and finally reviewed the medical records of 167 patients on ECMO support at a tertiary care university hospital between March 2002 and November 2011...
November 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28873299/redox-controls-over-the-stability-of-u-iv-in-floodplains-of-the-upper-colorado-river-basin
#17
Vincent Noël, Kristin Boye, Juan S Lezama Pacheco, Sharon E Bone, Noémie Janot, Emily Cardarelli, Kenneth H Williams, John R Bargar
Aquifers in the Upper Colorado River Basin (UCRB) exhibit persistent uranium (U) groundwater contamination plumes originating from former ore processing operations. Previous observations at Rifle, Colorado, have shown that fine grained, sulfidic, organic-enriched sediments accumulate U in its reduced form, U(IV), which is less mobile than oxidized U(VI). These reduced sediment bodies can subsequently act as secondary sources, releasing U back to the aquifer. There is a need to understand if U(IV) accumulation in reduced sediments is a common process at contaminated sites basin-wide, to constrain accumulated U(IV) speciation, and to define the biogeochemical factors controlling its reactivity...
September 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28866836/colistin-nephrotoxicity-in-the-icu-is-it-different-in-the-geriatric-patients
#18
Burcu Başarık Aydoğan, Fatma Yıldırım, Avşar Zerman, Kamil Gönderen, Melda Türkoğlu, Gülbin Aygencel
OBJECTIVE: Most significant side effect of colistin therapy which is used for the treatment of multi-drug resistant Gram-negative infections is nephrotoxicity. Our aim was to investigate the differences of colistin nephrotoxicity between the geriatric age group (≥65 years) and the younger age group (<65 years) in critically ill medical intensive care unit (ICU) patients. MATERIAL AND METHOD: The medical records of the 76 patients who were taken colistin therapy due to multi-resistant Gram-negative infections between January 2010 and June 2014 in the our medical ICU were retrospectively investigated...
September 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28806634/a-correlation-based-bullet-identification-method-using-empirical-mode-decomposition
#19
Saeed Bigdeli, Hamed Danandeh, Mohsen Ebrahimi Moghaddam
The striations on bullet surface are 3D micro structures formed when a bullet is forcing its way out of barrel. Each barrel leaves individual striation patterns on bullets. Hence, the striation information of bullets is helpful for firearm identification. Common automatic identification methods process these images using linear time invariant (LTI) filters based on correlation. These methods do not consider the sensitivity of correlation based comparisons to nonlinear baseline drifts. The striations are undeniably random unique micro structures caused by random non-model-based imperfections in the tools used in rifling process, therefore any characteristic profile that is extracted from a bullet image is statistically non-stationary...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28771061/comparison-of-performance-levels-and-sex-on-sprint-race-performance-in-the-biathlon-world-cup
#20
Harri Luchsinger, Jan Kocbach, Gertjan Ettema, Øyvind Sandbakk
Biathlon is an Olympic sport combining cross-country skiing with the skating technique and rifle shooting. The sprint (7.5 km for women and 10 km for men) includes two shootings between the three laps of skiing. The aims of the current study are to compare biathletes of different performance-levels and sex on total race time and performance-determining factors of sprint races in the biathlon World Cup. The top 10-performers (G1-10) and results within rank 21-30 (G21-30) in 47 sprint races during the 2011/2012 to 2015/2016 World Cup seasons were compared regarding total race time, course time, shooting time, range time, shooting performance (rate of hits) and penalty time...
August 3, 2017: International Journal of Sports Physiology and Performance
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