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https://www.readbyqxmd.com/read/28732314/the-effect-of-low-dose-furosemide-in-critically-ill-patients-with-early-acute-kidney-injury-a-pilot-randomized-blinded-controlled-trial-the-spark-study
#1
Sean M Bagshaw, R T Noel Gibney, Peter Kruger, Imran Hassan, Finlay A McAlister, Rinaldo Bellomo
PURPOSE: Furosemide is commonly prescribed in acute kidney injury (AKI). Prior studies have found conflicting findings on whether furosemide modifies the course and outcome of AKI. METHODS: Pilot multi-center randomized blinded placebo-controlled trial in adult patients with AKI admitted to three intensive care units. Participants were randomly allocated to furosemide bolus and infusion or 0.9% saline placebo. Primary endpoint was worsening AKI, defined by the RIFLE criteria...
July 12, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28717983/evaluation-of-acute-kidney-injury-aki-with-rifle-akin-ck-and-kdigo-in-critically-ill-trauma-patients
#2
F Ülger, M Pehlivanlar Küçük, A O Küçük, N K İlkaya, N Murat, B Bilgiç, H Abanoz
PURPOSE: The aim of our study was to evaluate the effects of AKI development on mortality with four different classification systems (RIFLE, AKIN, CK, KDIGO) in critically ill trauma patients followed in the intensive care unit. METHODS: A retrospective review of 2034 patients in our intensive care unit was conducted between July 2010 and August 2013. A total of 198 patients with primary trauma were included in the study to evaluate the development of AKI. RESULTS: When the presence of AKI was investigated according to the four criteria (RIFLE, AKIN, CK, and KDIGO), the highest incidence of AKI was found according to the KDIGO classification (74...
July 17, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28701840/colistin-nephrotoxicity-in-adults-single-centre-large-series-from-india
#3
Abdul Ghafur, Swati Gohel, Vidyalakshmi Devarajan, T Raja, Jose Easow, M A Raja, Sankar Sreenivas, Balasubramaniam Ramakrishnan, T Ramakrishnan, S G Raman, Dedeepiya Devaprasad, Balaji Venkatachalam, Ramesh Nimmagadda
CONTEXT: Limited Indian data are available on the rate of colistin nephrotoxicity and other risk factors contributing to the development of this important side effect. AIM: This study aims to generate data on colistin nephrotoxicity from a large cohort of Indian patients. DESIGN: Retrospective cohort study. MATERIALS AND METHODS: Case record analysis of patients who received colistin, in an oncology center in India, between January 2011 and December 2015...
June 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28692725/visual-speed-sensitivity-in-the-drum-corps-color-guard
#4
Nestor Matthews, Leslie Welch, F Daniel Coplin, Allison J Murphy, Megan R Puritz
Drum corps color guard experts spend years developing skills in spinning rifles, sabers, and flags. Their expertise provides a unique window into factors that govern sensitivity to the speed of rotational and radial motion. Prior neurophysiological research demonstrates that rotational and radial motion register in the Medial Superior Temporal (MST) region of the primate visual system. To the extent that shared neural events govern rotational and radial speed sensitivity, one would expect expertise on either task to transfer to the other...
July 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28670269/independent-component-analysis-and-source-localization-on-mobile-eeg-data-can-identify-increased-levels-of-acute-stress
#5
Bryan R Schlink, Steven M Peterson, W D Hairston, Peter König, Scott E Kerick, Daniel P Ferris
Mobile electroencephalography (EEG) is a very useful tool to investigate the physiological basis of cognition under real-world conditions. However, as we move experimentation into less-constrained environments, the influence of state changes increases. The influence of stress on cortical activity and cognition is an important example. Monitoring of modulation of cortical activity by EEG measurements is a promising tool for assessing acute stress. In this study, we test this hypothesis and combine EEG with independent component analysis and source localization to identify cortical differences between a control condition and a stressful condition...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28657951/firearm-deaths-in-america-can-we-learn-from-462-000-lives-lost
#6
Shelby Resnick, Randi N Smith, Jessica H Beard, Daniel Holena, Patrick M Reilly, C William Schwab, Mark J Seamon
OBJECTIVE: We sought to determine whether state firearm legislation correlated with firearm-related fatality rates (FFR) during a 15-year period. BACKGROUND: The politicized and controversial topic of firearm legislation has been grossly understudied when the relative impact of American firearm violence is considered. Scientific evidence regarding gun legislation effectiveness remains scant. METHODS: Demographic and intent data (1999-2013) were collected from the Centers for Disease Control and Prevention's Web-Based Injury Statistics Query and Reporting System database and compared by state firearm legislation rankings with respect to FFR...
June 27, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28656931/community-acquired-acute-kidney-injury-in-critically-ill-children-as-seen-in-the-emergency-unit-of-a-tertiary-hospital-in-enugu-southeast-nigeria
#7
C C Obichukwu, O I Odetunde, J M Chinawa, H U Okafor, D K Adiele, B C Ibe
BACKGROUND: Acute kidney injury (AKI) has been shown to be common in critically ill patients with associated very poor outcome. There is paucity of data regarding its epidemiology, particularly in developing countries. This study aims to assess the presence of AKI among critically ill children to determine its prevalence, outcome, and outcome determinants in children suffering from AKI. PATIENTS AND METHODS: This is a cross-sectional observational study of critically ill children admitted to the children emergency unit of University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu...
June 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28648260/broadening-the-perspective-on-gun-violence-an-examination-of-the-firearms-industry-1990-2015
#8
Victoria M Smith, Michael Siegel, Ziming Xuan, Craig S Ross, Sandro Galea, Bindu Kalesan, Eric Fleegler, Kristin A Goss
INTRODUCTION: Firearm violence injures or kills 100,000 Americans each year. This paper applies the Host-Agent-Vector-Environment model to this issue. Research on firearm violence tends to focus on two elements-the host (i.e., victims of firearm violence) and the environment (i.e., gun policies)-but little attention has been paid to the agent (the gun and ammunition) or the vector (firearm manufacturers, dealers, and the industry lobby). METHODS: Using Bureau of Alcohol, Tobacco, Firearms and Explosives data, trends in firearm manufacturing were investigated from 1990 to 2015...
June 17, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28647245/transport-and-humification-of-dissolved-organic-matter-within-a-semi-arid-floodplain
#9
Wenming Dong, Jiamin Wan, Tetsu K Tokunaga, Benjamin Gilbert, Kenneth H Williams
In order to understand the transport and humification processes of dissolved organic matter (DOM) within sediments of a semi-arid floodplain at Rifle, Colorado, fluorescence excitation-emission matrix (EEM) spectroscopy, humification index (HIX) and specific UV absorbance (SUVA) at 254nm were applied for characterizing depth and seasonal variations of DOM composition. Results revealed that late spring snowmelt leached relatively fresh DOM from plant residue and soil organic matter down into the deeper vadose zone (VZ)...
July 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28620269/cold-steel-weak-flesh-mechanism-masculinity-and-the-anxieties-of-late-victorian-empire
#10
Michael Brown
This article considers the reception and representation of advanced military technology in late nineteenth- and early twentieth-century Britain. It argues that technologies such as the breech-loading rifle and the machine gun existed in an ambiguous relationship with contemporary ideas about martial masculinities and in many cases served to fuel anxieties about the physical prowess of the British soldier. In turn, these anxieties encouraged a preoccupation in both military and popular domains with that most visceral of weapons, the bayonet, an obsession which was to have profound consequences for British military thinking at the dawn of the First World War...
March 15, 2017: Cultural and Social History: the Journal of the Social History Society
https://www.readbyqxmd.com/read/28616211/acute-kidney-injury-in-patients-with-severe-sepsis-or-septic-shock-a-comparison-between-the-risk-injury-failure-loss-of-kidney-function-end-stage-kidney-disease-rifle-acute-kidney-injury-network-akin-and-kidney-disease-improving-global-outcomes-kdigo-classifications
#11
Marta Pereira, Natacha Rodrigues, Iolanda Godinho, Joana Gameiro, Marta Neves, João Gouveia, Zélia Costa E Silva, José António Lopes
PURPOSE: Using the Risk, Injury, Failure, Loss of kidney function, End-stage kidney disease (RIFLE), Acute Kidney Injury Network (AKIN) and Kidney Disease: Improving Global Outcomes (KDIGO) systems, the incidence of acute kidney injury (AKI) and their ability to predict in-hospital mortality in severe sepsis or septic shock was compared. MATERIALS AND METHODS: We performed a retrospective analysis of 457 critically ill patients with severe sepsis or septic shock hospitalized between January 2008 and December 2014...
June 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28614406/learning-from-the-mistakes-of-others-how-female-elk-cervus-elaphus-adjust-behaviour-with-age-to-avoid-hunters
#12
Henrik Thurfjell, Simone Ciuti, Mark S Boyce
In animal behaviour, there is a dichotomy between innate behaviours (e.g., temperament or personality traits) versus those behaviours shaped by learning. Innate personality traits are supposedly less evident in animals when confounded by learning acquired with experience through time. Learning might play a key role in the development and adoption of successful anti-predator strategies, and the related adaptation has the potential to make animals that are more experienced less vulnerable to predation. We carried out a study in a system involving a large herbivorous mammal, female elk, Cervus elaphus, and their primary predator, i...
2017: PloS One
https://www.readbyqxmd.com/read/28613853/production-of-hydrogen-peroxide-in-groundwater-at-rifle-colorado
#13
Xiu Yuan, Peter S Nico, Xiang Huang, Tongxu Liu, Craig Ulrich, Kenneth H Williams, James A Davis
The commonly held assumption that photodependent processes dominate H2O2 production in natural waters has been recently questioned. Here, we present evidence for the unrecognized and light-independent generation of H2O2 in groundwater of an alluvial aquifer adjacent to the Colorado River near Rifle, CO. In situ detection using a sensitive chemiluminescent method suggests H2O2 concentrations ranging from lower than the detection limit (<1 nM) to 54 nM along the vertical profiles obtained at various locations across the aquifer...
June 30, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28607011/liposomal-amphotericin-b-nephrotoxicity-in-patients-with-hematological-malignancies-a-retrospective-cohort-analysis
#14
Marta Stanzani, Nicola Vianelli, Michele Cavo, Alessandro Maritati, Marta Morotti, Russell E Lewis
We retrospectively examined the incidence, onset, risk factors, and outcomes of renal injury during 103 treatment courses of liposomal amphotericin B (L-AMB) in 97 adult patients with hematological malignancies. All patients were analyzed before, during and after the administration of L-AMB, and renal injury was graded per the RIFLE criteria. Most patients (87.3%) received L-AMB at 3 mg/kg/day. Nearly two-thirds (61.7%) of treatment courses did not meet any RIFLE category for renal injury, while 19.4% of patients were classified at risk, 13...
June 12, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28596039/assessment-of-aortic-wall-thrombus-predicts-outcomes-of-endovascular-repair-of-complex-aortic-aneurysms-using-fenestrated-and-branched-endografts
#15
Mauricio Ribeiro, Gustavo S Oderich, Thanila Macedo, Terri J Vrtiska, Jan Hofer, Julia Chini, Bernardo Mendes, Stephen Cha
OBJECTIVE: The goal of this study was to investigate the correlation between atherothrombotic aortic wall thrombus (AWT) and clinical outcomes in patients treated by fenestrated-branched endovascular aortic repair (F-BEVAR) and present a new classification system for assessment of AWT burden. METHODS: The clinical data of 301 patients treated for pararenal and thoracoabdominal aortic aneurysms (TAAAs) by F-BEVAR was reviewed. The study excluded 89 patients with extent I to III TAAA because of extensive laminated thrombus within the aneurysm sac...
June 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28578358/incidence-and-outcome-of-acute-kidney-injury-by-the-prifle-criteria-for-children-receiving-extracorporeal-membrane-oxygenation-after-heart-surgery
#16
Raja Abou Elella, Eiad Habib, Pavla Mokrusova, Princy Joseph, Hani Aldalaty, Mamdouh Al Ahmadi, Zohair Al Halees
BACKGROUND: Acute kidney injury (AKI) is common in patients treated with extracorporeal membrane oxygenation (ECMO). The RIFLE criteria demonstrate clinical relevance for diagnosing AKI and classifying its severity. OBJECTIVES: To systematically define the incidence, clinical course and outcome of AKI using the pediatric pRIFLE criteria. DESIGN: Retrospective, medical records review. SETTINGS: Pediatric cardiac surgical intensive care units at a tertiary care hospital in Riyadh...
May 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28530482/the-effect-of-backpack-load-carriage-on-the-kinetics-and-kinematics-of-ankle-and-knee-joints-during-uphill-walking
#17
Jinkyu Lee, Yong-Jin Yoon, Choongsoo S Shin
The purpose of this study was to investigate the effect of load carriage on the kinematics and kinetics of the ankle and knee joints during uphill walking, including joint work, range of motion (ROM), and stance time. Fourteen males walked at a self-selected speed on an uphill (15°) slope wearing military boots and carrying a rifle in hand without a backpack (control condition) and with a backpack. The results showed that the stance time significantly decreased with backpack carriage (p<.05). The mediolateral impulse significantly increased with backpack carriage (p<...
May 22, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28473672/colistin-associated-nephrotoxicity-among-patients-in-intensive-care-units-icu-of-hospitals-in-selangor
#18
M R Rashizal Sazli, A F Syed Mohamed, W M Wan Mazuan, S M Ling, A Mahmud, S Amin Nordin
INTRODUCTION: The increasing trend of extensively drugresistant gram negative bacteria responsible for nosocomial infections has prompted resurgence colistin usage. Colistin-induced nephrotoxicity is a concern with disparity in the reported rates between previous studies. This study aims to evaluate colistin-induced nephrotoxicity among Malaysian population. METHODS: The medical records of ICU patients receiving colistin therapy in Hospital Serdang and Hospital Sungai Buloh from 2010 to 2012 were retrospectively reviewed...
April 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28471979/effects-of-6-hydroxyethyl-starch-130-0-4-on-postoperative-blood-loss-and-kidney-injury-in-off-pump-coronary-arterial-bypass-grafting-a-retrospective-study
#19
Jeong Jin Min, Hyun Sung Cho, Suyong Jeon, Jong-Hwan Lee, Jeong Jin Lee, Young Tak Lee
We retrospectively evaluated the effects of 6% hydroxyethyl starch (HES) 130/0.4 on postoperative blood loss and acute kidney injury (AKI) in patients undergoing off-pump coronary artery bypass grafting (OPCAB).Electronic medical records of 771 patients who underwent OPCAB in our hospital between July 2012 and July 2014 were reviewed, and 249 patients without intraoperative HES-exposure (group NoHES) were matched 1:N with intraoperative HES-exposed 413 patients (group HES) based on propensity score. The effects of intraoperative HES on postoperative cumulative blood loss within the first 24 hours, need for bleeding-related reoperation, and occurrence of postoperative AKI (determined by KDIGO and RIFLE criteria) were analyzed...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28464307/statistical-approaches-to-type-determination-of-the-ejector-marks-on-cartridge-cases
#20
Eric M Warren, H David Sheets
While type determination on bullets has been performed for over a century, type determination on cartridge cases is often overlooked. Presented here is an example of type determination of ejector marks on cartridge cases from Glock and Smith & Wesson Sigma series pistols using Naïve Bayes and Random Forest classification methods. The shapes of ejector marks were captured from images of test-fired cartridge cases and subjected to multivariate analysis. Naïve Bayes and Random Forest methods were used to assign the ejector shapes to the correct class of firearm with success rates as high as 98%...
May 2, 2017: Journal of Forensic Sciences
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