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https://www.readbyqxmd.com/read/28806038/partnership-strategies-of-community-health-centers-building-capacity-in-good-times-and-bad
#1
Maria-Elena Young, Steven P Wallace, Amy Bonilla, Nadereh Pourat, Michael Rodriguez
Federally Qualified Health Centers--commonly referred to as Community Health Centers (CHCs)--serve as critical safety net providers for those who are uninsured or who may become uninsured. This policy brief reports the findings from the Remaining Uninsured Access to Community Health Centers (REACH) research project, which sought to identify the impact of the Affordable Care Act (ACA) on the ability of CHCs to serve the remaining uninsured. We examined strategies undertaken by CHCs in four states to reinforce the local safety net through partnerships, improvements to the local health system, and advocacy...
July 2017: Policy Brief
https://www.readbyqxmd.com/read/28805362/how-the-affordable-care-act-has-helped-women-gain-insurance-and-improved-their-ability-to-get-health-care-findings-from-the-commonwealth-fund-biennial-health-insurance-survey-2016
#2
Munira Z Gunja, Sara R Collins, Michelle M Doty, Sophie Beautel
ISSUE: Prior to the Affordable Care Act (ACA), one-third of women who tried to buy a health plan on their own were either turned down, charged a higher premium because of their health, or had specific health problems excluded from their plans. Beginning in 2010, ACA consumer protections, particularly coverage for preventive care screenings with no cost-sharing and a ban on plan benefit limits, improved the quality of health insurance for women. In 2014, the law’s major insurance reforms helped millions of women who did not have employer insurance to gain coverage through the ACA’s marketplaces or through Medicaid...
August 2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/28803697/tumor-necrosis-factor-alpha-gene-polymorphisms-and-haplotypes-in-egyptian-children-with-nephrotic-syndrome
#3
Doaa M Youssef, Amal S El-Shal, Samia Hussein, Khaled Salah, Abd El Rahman E Ahmed
BACKGROUND: Nephrotic syndrome (NS) characterized by complex pathogenesis and clinical course with relapses; and needs novel breakthroughs for decades. Polymorphisms of cytokines genes including tumor necrosis factor alpha (TNF-α)may influence susceptibility to NS as well as different patients' steroid responses. In the current study, we demonstrated the potential roles of TNF-α promoter gene polymorphisms [-238, -308, -863] and haplotypes in susceptibility to childhood NS. Also, elucidating their possible influence on patients' steroid response and serum TNF-α level...
August 10, 2017: Cytokine
https://www.readbyqxmd.com/read/28801466/statewide-payment-and-delivery-reform-do-states-have-what-it-takes
#4
Judy Feder, Alan R Weil, Robert Berenson, Rachel Dolan, Nicole Lallemand, Emily Hayes
States' role in payment as well as coverage will be subject to debate as the administration and the Congress decide how to address the Affordable Care Act (ACA) and otherwise reshape the nation's health policies. Acting as stewards of health care for the entire state population and stimulated by concern about rising costs and federal support under the ACA, the elected and administrative leaders of some states have been using their political influence and authority to improve their state's overall systems of care regardless of who pays the bill...
August 11, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28801463/shaping-health-policy-for-low-income-populations-an-assessment-of-public-comments-in-a-new-medicaid-waiver-process
#5
Marian Jarlenski, Philip Rocco, Renuka Tipirneni, Amy Jo Kennedy, Nivedita Gunturi, Julie Donohue
Since the Supreme Court decided that the Affordable Care Act's (ACA) Medicaid expansion is optional for the states, several have obtained federal approval to use Section 1115 waivers to expand Medicaid while changing its coverage and benefits design. There has long been concern that policy making for Medicaid populations may lack meaningful engagement with low-income constituents, and therefore the ACA established a new process under which the public can submit comments on pending Medicaid waiver applications...
August 11, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28798741/deinococcus-radiodurans-toxin-antitoxin-mazef-dr-mediates-cell-death-in-response-to-dna-damage-stress
#6
Tao Li, Yulan Weng, Xiaoqiong Ma, Bing Tian, Shang Dai, Ye Jin, Mengjia Liu, Jiulong Li, Jiangliu Yu, Yuejin Hua
Here we identified a functional MazEF-dr system in the exceptionally stress-resistant bacterium D. radiodurans. We showed that overexpression of the toxin MazF-dr inhibited the growth of Escherichia coli. The toxic effect of MazF-dr was due to its sequence-specific endoribonuclease activity on RNAs containing a consensus 5'ACA3', and it could be neutralized by MazE-dr. The MazF-dr showed a special cleavage preference for the nucleotide present before the ACA sequence with the order by U>A>G>C. MazEF-dr mediated the death of D...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28792848/small-change-big-consequences-partial-medicaid-expansions-under-the-aca
#7
Adrianna McIntyre, Allan M Joseph, Nicholas Bagley
Though congressional efforts to repeal and replace the Affordable Care Act (ACA) seem to have stalled, the Trump administration retains broad executive authority to reshape the health care landscape. Perhaps the most consequential choices that the administration will make pertain to Medicaid, which..
August 9, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28792400/dismantling-the-aca-without-help-from-congress
#8
Susan Jaffe
No abstract text is available yet for this article.
July 29, 2017: Lancet
https://www.readbyqxmd.com/read/28790006/the-relationship-between-the-direction-of-putaminal-intracerebral-hemorrhage-and-anterior-cerebral-artery-predominance
#9
Jae-Ho Lee, Chul-Hoon Chang, Young-Jin Jung, Jong-Hoon Kim
INTRODUCTION: It is expected that anatomical variations in the circle of Willis have a direct effect on blood flow in the internal carotid artery. Rupture of the lenticulostriate artery of the middle cerebral artery 1st segment (M1) is the most common cause of putaminal intracerebral hemorrhage(ICH), and we hypothesized that this could be related to the anatomical variations of the circle of Willis and the predominance of the anterior cerebral artery 1st segment (A1). METHODS: We retrospectively reviewed the records of 544 patients who were treated for spontaneous ICH between 2013 and 2016 at Yeungnam University Hospital...
August 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28771602/affordable-care-act-and-healthcare-delivery-a-comparison-of-california-and-florida-hospitals-and-emergency-departments
#10
Monique T Barakat, Aditi Mithal, Robert J Huang, Alka Mithal, Amrita Sehgal, Subhas Banerjee, Gurkirpal Singh
IMPORTANCE: The Affordable Care Act (ACA) has expanded access to health insurance for millions of Americans, but the impact of Medicaid expansion on healthcare delivery and utilization remains uncertain. OBJECTIVE: To determine the early impact of the Medicaid expansion component of ACA on hospital and ED utilization in California, a state that implemented the Medicaid expansion component of ACA and Florida, a state that did not. DESIGN: Analyze all ED encounters and hospitalizations in California and Florida from 2009 to 2014 and evaluate trends by payer and diagnostic category...
2017: PloS One
https://www.readbyqxmd.com/read/28770876/assessment-of-the-underlying-causes-of-the-immune-thrombocytopenia-ten-years-experience
#11
Mehmet Sinan Dal, Abdullah Karakus, Tuba Dal, Berrin Balik Aydin, Elif Hattapoglu, Mehmet Onder Ekmen, Turgay Ulas, Orhan Ayyildiz
OBJECTIVE: Immune thrombocytopenia (ITP) is an immune haematologic disorder causing platelet destruction mediated by anti-platelet antibodies. In this study we aimed to evaluate the clinical and laboratory variables of ITP patients in southeast of Turkey. METHODS: In this retrospective study 167 ITP patients between 2005 and 2015 were evaluated. All patients were screened for immunological parameters including ANA (antinuclear antibodies), anti dsDNA (anti-double-stranded-DNA), ACA(anti-cardiolipin) IgM and IgG, LA (lupus anticoagulants)...
July 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28769133/the-prevalence-of-ana-antibodies-anticentromere-antibodies-and-anti-cyclic-citrullinated-peptide-antibodies-in-patients-with-primary-sj%C3%A3-gren-s-syndrome-compared-to-patients-with-dryness-symptoms-without-primary-sj%C3%A3-gren-s-syndrome-confirmation
#12
Maria Maślińska, Małgorzata Mańczak, Bożena Wojciechowska, Brygida Kwiatkowska
OBJECTIVES: Our study analyses the prevalence of ANA, anti-SS-A, anti-SS-B, and ACA and ACPA antibodies in patients with pSS and with dryness symptoms without pSS confirmation, and the association of ACPA and ACA antibodies with specific clinical symptoms. MATERIALS AND METHODS: 113 patients were divided into two groups: I - with diagnosed pSS (N = 75); and II - with dryness without pSS evidence (N = 38). Diagnostics: indirect immunofluorescence (IF; Hep-2 cell line) of antinuclear antibodies (ANA), anti-SS-A anti-SS-B antibodies determined with semi-quantitative method, autoantibody profile (14 antigens, ANA Profil 3 EUROLINE); basic laboratory, ophthalmic examination tests, minor salivary gland biopsy with focus score (FS), joint and lung evaluation, and ESSDAI questionnaire (pSS activity)...
2017: Reumatologia
https://www.readbyqxmd.com/read/28765030/relationship-of-a1-segment-hypoplasia-to-the-radiological-and-clinical-outcomes-of-surgical-clipping-anterior-communicating-artery-aneurysm
#13
Fan Yang, Hao Li, Jun Wu, Maogui Li, Xin Chen, Pengjun Jiang, Zhengsong Li, Yong Cao, Shuo Wang
OBJECTIVE: This study aims to assess whether the A1 segment hypoplasia is a risk factor for unfavorable radiological and clinical outcomes of surgical clipping anterior communicating artery (ACoA) aneurysm. METHODS: We retrospectively reviewed 251 patients with ACoA aneurysm who underwent surgical clipping in Beijing Tiantan Hospital between September 2011 and September 2016. Their clinical and radiologic features, as well as clinical outcomes were reviewed. In addition, univariate and multivariate logistic regression analysis was performed to identify independent risk factors for the postoperative infarction and unfavorable clinical outcomes of surgical clipping ACoA aneurysm...
July 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28764948/effects-of-the-incorporation-of-%C3%AE%C2%B5-aminocaproic-acid-chitosan-particles-to-fibrin-on-cementoblast-differentiation-and-cementum-regeneration
#14
Chan Ho Park, Joung-Hwan Oh, Hong-Moon Jung, Yoonnyoung Choi, Saeed Rahman, Sungtae Kim, Tae-Il Kim, Hong-In Shin, Yun-Sil Lee, Frank H Yu, Jeong-Hwa Baek, Hyun-Mo Ryoo, Kyung Mi Woo
Cementum formation on the exposed tooth-root surface is a critical process in periodontal regeneration. Although various therapeutic approaches have been developed, regeneration of integrated and functional periodontal complexes is still wanting. Here, we found that the OCCM30 cementoblasts cultured on fibrin matrix express substantial levels of matrix proteinases, leading to the degradation of fibrin and the apoptosis of OCCM30 cells, which was reversed upon treatment with a proteinase inhibitor, ε-aminocaproic acid (ACA)...
July 29, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28764041/monitoring-the-progression-of-calcium-and-protein-solubilisation-as-affected-by-calcium-chelators-during-small-scale-manufacture-of-casein-based-food-matrices
#15
Irene McIntyre, Michael O'Sullivan, Dolores O'Riordan
Calcium and protein solubilisation during small-scale manufacture of semi-solid casein-based food matrices was investigated and found to be very different in the presence or absence of calcium chelating salts. Calcium concentrations in the dispersed phase increased and calcium-ion activity (ACa(++)) decreased during manufacture of the matrices containing calcium chelating salts; with ∼23% of total calcium solubilised by the end of manufacture. In the absence of calcium chelating salts, these concentrations were significantly lower at equivalent processing times and remained unchanged as did ACa(++), throughout manufacture...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28763780/treatment-use-sources-of-payment-and-financial-barriers-to-treatment-among-individuals-with-opioid-use-disorder-following-the-national-implementation-of-the-aca
#16
Ryan M McKenna
INTRODUCTION: Despite increasing rates of opioid misuse and hospitalizations, rates of treatment for those with opioid use disorder (OUD) are very low. This study examined the impact of the Patient Protection and Affordable Care Act's (ACA) insurance expansion on improving rates of insurance, health care access, and treatment for those with OUD. METHODS: Data on individuals ages 18-64 with OUD come from the 2008-2014 National Survey on Drug Use and Health (N=4100)...
July 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28762193/probiotic-features-of-lactic-acid-bacteria-isolated-from-a-diverse-pool-of-traditional-greek-dairy-products-regarding-specific-strain-host-interactions
#17
Georgia Zoumpopoulou, Alexandra Tzouvanou, Eleni Mavrogonatou, Voula Alexandraki, Marina Georgalaki, Rania Anastasiou, Marina Papadelli, Eugenia Manolopoulou, Maria Kazou, Dimitris Kletsas, Konstantinos Papadimitriou, Effie Tsakalidou
The increased consumers' interest on the positive role of food in wellbeing and health underscores the need to determine new probiotic microorganisms. Triggered by the fact that artisanal food products can be a valuable source of novel probiotic strains, 106 lactic acid bacteria, all isolated from traditional Greek dairy products, namely Feta, Kasseri, Xynotyri, Graviera, Formaela, Galotyri, and Kefalotyri cheeses as well as yogurt and milk, were studied for probiotic properties. Based on their survival at pH 2...
July 31, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28761568/the-effects-of-ramadan-fasting-on-anterior-segment-parameters-visual-acuity-and-intraocular-pressures-of-the-eye
#18
Ozlem Barut Selver, Melis Palamar, Kevser Gerceker, Sait Egrilmez, Ayse Yagci
OBJECTIVE: It is aimed to determine whether fasting during Ramadan has any significant effect on anterior chamber parameters, visual acuity and intraocular pressures. METHODS: 31 fasting (Group 1) and 30 non-fasting healthy volunteers (Group 2) were enrolled. All cases underwent an ophthalmological examination and anterior segment parameter evaluation (central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pupil size) with Pentacam before and after the breaking of the Ramadan fast in Group 1, before and after dinner in Group 2...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28761166/anti-centromere-antibody-exhibits-specific-distribution-levels-among-anti-nuclear-antibodies-and-may-characterize-a-distinct-subset-in-rheumatoid-arthritis
#19
Nobuo Kuramoto, Koichiro Ohmura, Katsunori Ikari, Koichiro Yano, Moritoshi Furu, Noriyuki Yamakawa, Motomu Hashimoto, Hiromu Ito, Takao Fujii, Kosaku Murakami, Ran Nakashima, Yoshitaka Imura, Naoichiro Yukawa, Hajime Yoshifuji, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka, Fumihiko Matsuda, Tsuneyo Mimori, Chikashi Terao
Anti-centromere antibody (ACA) is one of the classical anti-nuclear antibody (ANA) staining patterns. However, characteristics of ACA in comparison with the other ANA patterns and clinical features of ACA-positive subjects have not been elucidated. Here, we examined all ANA patterns by indirect immunofluorescence for 859 rheumatoid arthritis (RA) patients. Together with the ANA data of 9,575 healthy volunteers, we compared distributions of the ANA levels. ACA was the only ANA that demonstrated a definite bimodal distribution of levels...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28756120/comparison-of-two-strategies-for-ex-vivo-lung-perfusion
#20
Tobias Nilsson, Jan F Gielis, Alexis Slama, Christoffer Hansson, Andreas Wallinder, Sven-Erik Ricksten, Göran Dellgren
BACKGROUND: Two clinically used strategies for ex vivo lung perfusion (EVLP) were compared in a porcine model with respect to lung function, metabolism, inflammatory response, oxidative stress, and cell viability. METHODS: Porcine lungs (n = 20) were preserved, harvested, and kept cooled for 2 hours. After randomization, EVLP was performed using a cellular perfusate and open left atrium (COA group) or an acellular perfusate and a closed left atrium (ACA group). Oxygenation (partial pressure of arterial oxygen/fraction of inspired oxygen), compliance, dead space, weight, and perfusate oncotic pressure were registered before and after a 4-hour period of reconditioning...
July 8, 2017: Journal of Heart and Lung Transplantation
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