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https://www.readbyqxmd.com/read/27909937/exploring-the-migration-profiles-of-primary-healthcare-users-in-south-africa
#1
Jo Vearey, Thea de Gruchy, Mphatso Kamndaya, Helen L Walls, Candice M Chetty-Makkan, Johanna Hanefeld
South Africa's public healthcare system responses seldom engage with migration. Our exploratory study investigates migration profiles and experiences of primary healthcare (PHC) users. A cross-sectional survey involving non-probability sampling was conducted with 229 PHC users at six purposively selected PHC clinics in three districts of SA. The survey captured socio-demographic information, migration histories, and PHC experiences. Chi square and Fischer's exact tests were used to compare categorical variables, whilst Mann-Whitney U tests compared continuous variables between groups...
December 1, 2016: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/27884371/committing-to-disability-inclusion-to-end-aids-by-2030
#2
Jill Hanass-Hancock, Paul Chappell, Hellen Myezwa, Betty Kwagala, Jean-Marc Boivin, Jacques Lloyd, Gustaaf Wolvaardt, Phillimon Simwaba, Verusia Chetty
No abstract text is available yet for this article.
December 2016: Lancet HIV
https://www.readbyqxmd.com/read/27884119/anti-lrp-lr-specific-antibody-igg1-is18-impedes-adhesion-and-invasion-of-pancreatic-cancer-and-neuroblastoma-cells
#3
Thalia M Rebelo, Carryn J Chetty, Eloise Ferreira, Stefan F T Weiss
BACKGROUND: Cancer has become a global burden due to its high incidence and mortality rates, with an estimated 14.1 million cancer cases reported worldwide in 2012 particularly as a result of metastasis. Metastasis involves two crucial steps: adhesion and invasion, and the non-integrin receptor; the 37-kDa/67-kDa laminin receptor precursor/ high affinity laminin receptor (LRP/LR) has been shown to be overexpressed on the surface of tumorigenic cells, thus being implicated in the enhancement of these two crucial steps...
November 24, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27857298/robust-air-refractometer-for-accurate-compensation-of-the-refractive-index-of-air-in-everyday-use
#4
O Kruger, N Chetty
The definition of the meter is based on the speed of light in a vacuum; however, most dimensional measurements, when performed using laser interferometry, are performed in air. A velocity of light compensation needs to be applied to the velocity of the laser light for accurate measurements of the speed of light to be approximated in a vacuum. Most practices use a weather-station method, whereby the ambient conditions are measured. Thereafter, the modified Edlén's equation is used, and corrections are calculated for the wavelength of the laser...
November 10, 2016: Applied Optics
https://www.readbyqxmd.com/read/27853056/an-evaluation-of-the-health-and-wellbeing-needs-of-employees-an-organizational-case-study
#5
Laran Chetty
INTRODUCTION: Workplace health and wellbeing is a major public health issue for employers. Wellbeing health initiatives are known to be cost-effective, especially when the programs are targeted and matched to the health problems of the specific population. The aim of this paper is to gather information about the health and wellbeing needs and resources of employees at one British organization. SUBJECTS AND METHODS: A cross-sectional survey was carried out to explore the health and wellbeing needs and resources of employees at one British organization...
November 16, 2016: Journal of Occupational Health
https://www.readbyqxmd.com/read/27824575/analysis-of-current-pulses-in-hela-cell-permeabilization-due-to-high-voltage-dc-corona-discharge
#6
Nevendra K Chetty, Louis Chonco, Nelson M Ijumba, Leon Chetty, Thavendran Govender, Raveen Parboosing, Innocent E Davidson
Corona discharges are commonly utilized for numerous practical applications, including bio-technological ones. The corona induced transfer of normally impermeant molecules into the interior of biological cells has recently been successfully demonstrated. The exact nature of the interaction of the corona discharge with a cell membrane is still unknown, however, previous studies have suggested that it is either the electric fields produced by ions or the chemical interaction of the reactive species that result in the disruption of the cell membrane...
September 2016: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/27798004/cohort-profile-the-hlabisa-pregnancy-cohort-kwazulu-natal-south-africa
#7
Terusha Chetty, Claire Thorne, Frank Tanser, Till Bärnighausen, Anna Coutsoudis
PURPOSE: The Hlabisa pregnancy cohort was established to evaluate the effectiveness of prevention of mother-to-child transmission (PMTCT) guideline revisions. The objectives of the Hlabisa pregnancy cohort are to: (1) provide cohort-level information on maternal health up to 6 weeks postpartum in a high HIV prevalence setting; and to (2) evaluate aspects of PMTCT care that have policy relevance. PARTICIPANTS: The pregnancy cohort is located in primary health clinics in the Hlabisa subdistrict of rural KwaZulu-Natal, South Africa...
October 17, 2016: BMJ Open
https://www.readbyqxmd.com/read/27782712/use-of-regularized-principal-component-analysis-to-model-anatomical-changes-during-head-and-neck-radiation-therapy-for-treatment-adaptation-and-response-assessment
#8
Mikhail A Chetvertkov, Farzan Siddiqui, Jinkoo Kim, Indrin Chetty, Akila Kumarasiri, Chang Liu, J James Gordon
PURPOSE: To develop standard (SPCA) and regularized (RPCA) principal component analysis models of anatomical changes from daily cone beam CTs (CBCTs) of head and neck (H&N) patients and assess their potential use in adaptive radiation therapy, and for extracting quantitative information for treatment response assessment. METHODS: Planning CT images of ten H&N patients were artificially deformed to create "digital phantom" images, which modeled systematic anatomical changes during radiation therapy...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27736211/effects-of-local-health-interventions-on-inequality-in-life-expectancy-new-publicly-available-data
#9
Raj Chetty, David Cutler, Michael Stepner
No abstract text is available yet for this article.
December 2016: American Journal of Public Health
https://www.readbyqxmd.com/read/27725012/molecular-detection-of-carbapenemase-producing-genes-in-referral-enterobacteriaceae-in-south-africa-a-short-report
#10
O Perovic, E Britz, V Chetty, A Singh-Moodley
Molecular confirmation of carbapenemase-producing Enterobacteriaceae (CPE) was introduced in South Africa (SA) at the end of 2011. We report on the detection of these resistance genes based on referral isolates. Enterobacteriaceae with non-susceptibility to any of the carbapenems according to defined criteria for antimicrobial susceptibility testing results were sent to a reference laboratory. A proportion of isolates had limited demographic, epidemiological and clinical data available. Organism identification was reconfirmed using reference laboratory methods, and the presence of carbapenemases was confirmed with a real-time polymerase chain reaction...
September 6, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27716323/precise-film-dosimetry-for-stereotactic-radiosurgery-and-stereotactic-body-radiotherapy-quality-assurance-using-gafchromic%C3%A2-ebt3-films
#11
Ning Wen, Siming Lu, Jinkoo Kim, Yujiao Qin, Yimei Huang, Bo Zhao, Chang Liu, Indrin J Chetty
PURPOSE: The purpose of this study is to evaluate the dosimetric uncertainty associated with Gafchromic™ (EBT3) films and establish a practical and efficient film dosimetry protocol for Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiotherapy (SBRT). METHOD AND MATERIALS: EBT3 films were irradiated at each of seven different dose levels between 1 and 15 Gy with open fields and standard deviations of dose maps were calculated at each color channel for evaluation...
October 4, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27688047/optimization-of-treatment-geometry-to-reduce-normal-brain-dose-in-radiosurgery-of-multiple-brain-metastases-with-single-isocenter-volumetric-modulated-arc-therapy
#12
Qixue Wu, Karen Chin Snyder, Chang Liu, Yimei Huang, Bo Zhao, Indrin J Chetty, Ning Wen
Treatment of patients with multiple brain metastases using a single-isocenter volumetric modulated arc therapy (VMAT) has been shown to decrease treatment time with the tradeoff of larger low dose to the normal brain tissue. We have developed an efficient Projection Summing Optimization Algorithm to optimize the treatment geometry in order to reduce dose to normal brain tissue for radiosurgery of multiple metastases with single-isocenter VMAT. The algorithm: (a) measures coordinates of outer boundary points of each lesion to be treated using the Eclipse Scripting Application Programming Interface, (b) determines the rotations of couch, collimator, and gantry using three matrices about the cardinal axes, (c) projects the outer boundary points of the lesion on to Beam Eye View projection plane, (d) optimizes couch and collimator angles by selecting the least total unblocked area for each specific treatment arc, and (e) generates a treatment plan with the optimized angles...
September 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27681847/regression-grading-in-neoadjuvant-treated-pancreatic-cancer-an-interobserver-study
#13
Sangeetha N Kalimuthu, Stefano Serra, Neesha Dhani, Sara Hafezi-Bakhtiari, Eva Szentgyorgyi, Rajkumar Vajpeyi, Runjan Chetty
AIM: Several regression grading systems have been proposed for neoadjuvant chemoradiation-treated pancreatic ductal adenocarcinoma (PDAC). This study aimed to examine the utility, reproducibility and level of concordance of three most frequently used grading systems. METHODS: Four gastrointestinal pathologists used the College of American Pathologists (CAP), Evans, MD Anderson Cancer Centre (MDA) regression grading systems to grade 14 selected cases (7-20 slides from each case) of neoadjuvant chemoradiation-treated PDAC...
September 28, 2016: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27676067/prediction-of-response-to-radiation-therapy-treatment-of-head-and-neck-cancers-using-an-artificial-neural-network-developed-from-cone-beam-computed-tomography-image-textural-information
#14
H Bagher-Ebadian, F Siddiqui, C Liu, B Movsas, I J Chetty
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675330/the-projection-summing-optimization-algorithm-can-effectively-reduce-normal-brain-dose-in-stereotactic-radiosurgery-of-multiple-brain-metastases-with-single-isocenter
#15
Q Wu, N Wen, K C Snyder, C Liu, Y Huang, B Zhao, I J Chetty, M M Shah, B Movsas, S Siddiqui
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675180/a-physiologically-nested-pharmacokinetic-model-in-dynamic-contrast-enhanced-magnetic-resonance-imaging-for-detection-of-dominant-intraprostatic-lesions-in-patients-with-prostate-cancer
#16
N Wen, H Bagher-Ebadian, M Pantelic, D Hearshen, M A Elshaikh, I J Chetty, B Movsas
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675105/toward-a-noninvasive-measurement-of-cancer-stem-cells-and-tumor-aggressiveness
#17
S L Brown, R Elmghirbi, T Nagaraja, K A Keenan, K Lapanowski, S Panda, P Inder, G Cabral, L Liu, J H Kim, B Movsas, I J Chetty, J R Ewing, R Parry
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674948/do-race-and-income-influence-quality-of-life-qol-or-survival-outcomes-after-lung-stereotactic-body-radiation-therapy-sbrt-a-prospective-study
#18
S Vance, K A Al Feghali, A Taylor, M Kaur, C Neslund-Dudas, I J Chetty, M Simoff, M Ajlouni, B Movsas
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27669564/the-epidemiology-of-meningitis-among-adults-in-a-south-african-province-with-a-high-hiv-prevalence-2009-2012
#19
Erika Britz, Olga Perovic, Claire von Mollendorf, Anne von Gottberg, Samantha Iyaloo, Vanessa Quan, Verushka Chetty, Charlotte Sriruttan, Nazir A Ismail, Ananta Nanoo, Alfred Musekiwa, Carl Reddy, Karien Viljoen, Cheryl Cohen, Nelesh P Govender
INTRODUCTION: Meningitis is a major cause of mortality in southern Africa. We aimed to describe the aetiologies and frequencies of laboratory-confirmed fungal and bacterial meningitis among adults in a South African province with an 11% HIV prevalence, over 4 years. METHODS: We conducted a retrospective, observational study of secondary laboratory data, extracted on all cerebrospinal fluid (CSF) specimens submitted to public-sector laboratories in Gauteng province from 2009 through 2012...
2016: PloS One
https://www.readbyqxmd.com/read/27659780/to-gate-or-not-to-gate-dosimetric-evaluation-comparing-gated-vs-itv-based-methodologies-in-stereotactic-ablative-body-radiotherapy-sabr-treatment-of-lung-cancer
#20
Joshua Kim, Qixue Wu, Bo Zhao, Ning Wen, Munther Ajlouni, Benjamin Movsas, Indrin J Chetty
BACKGROUND: To compare retrospectively generated gated plans to conventional internal target volume (ITV)-based plans and to evaluate whether gated radiotherapy provides clinically relevant dosimetric improvements to organs-at-risk (OARs). METHODS: Evaluation was performed of 150 stereotactic ablative radiotherapy treatment plans delivered to 128 early-stage (T1-T3 (<5 cm)) NSCLC patients. To generate gated plans, original ITV-based plans were re-optimized and re-calculated on the end-exhale phase and using gated planning target volumes (PTV)...
September 22, 2016: Radiation Oncology
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