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https://www.readbyqxmd.com/read/28213135/genetic-variants-in-the-peripheral-auditory-system-significantly-affect-adult-cochlear-implant-performance
#1
A Eliot Shearer, Robert W Eppsteiner, Kathy Frees, Viral Tejani, Christina M Sloan-Heggen, Carolyn Brown, Paul Abbas, Camille Dunn, Marlan R Hansen, Bruce J Gantz, Richard J H Smith
BACKGROUND: Cochlear implantation is an effective habilitation modality for adults with significant hearing loss. However, post-implant performance is variable. A portion of this variance in outcome can be attributed to clinical factors. Recent physiological studies suggest that the health of the spiral ganglion also impacts post-operative cochlear implant outcomes. The goal of this study was to determine whether genetic factors affecting spiral ganglion neurons may be associated with cochlear implant performance...
February 14, 2017: Hearing Research
https://www.readbyqxmd.com/read/28211101/dental-status-as-a-predictor-of-mortality-among-nursing-facility-residents-in-eastern-iowa
#2
Daniel J Caplan, Tariq S Ghazal, Howard J Cowen, Deise C Oliveira
OBJECTIVE: This study aimed to evaluate dental status (ie, number of teeth and presence of removable dental prostheses) as a predictor of all-cause mortality among nursing facility residents. BACKGROUND: Edentulism has been associated with poorer health outcomes in geriatric populations. MATERIALS AND METHODS: Between March 2006 and June 2008, oral health screening examinations were completed for 584 residents of 10 nursing facilities in four eastern Iowa counties...
February 16, 2017: Gerodontology
https://www.readbyqxmd.com/read/28208814/adequacy-of-usual-vitamin-and-mineral-intake-in-spanish-children-and-adolescents-enalia-study
#3
Ana M López-Sobaler, Aránzazu Aparicio, Liliana G González-Rodríguez, Esther Cuadrado-Soto, Josefa Rubio, Victoria Marcos, Rosa Sanchidrián, Sara Santos, Napoleón Pérez-Farinós, Marian Ángeles Dal Re, Carmen Villar, Teresa Robledo, J Javier Castrodeza, Rosa M Ortega
Background: The National Dietary Survey on the Child and Adolescent Population in Spain (ENALIA) provides data to assess the usual micronutrient intake among Spanish infants, children, and adolescents. Methods: Cross-sectional survey (November 2012-July 2014) of a representative sample of Spanish children and adolescents (six months-17 years) (n = 1862). Dietary information was collected using two non-consecutive one-day food diaries (six months-10 years old) or two 24 h dietary recalls (11 years and older) separated by at least 14 days...
February 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28198658/effects-of-acute-and-chronic-caffeine-on-risk-taking-behavior-in-children-and-adolescents
#4
Jennifer L Temple, Amanda M Ziegler, Adam M Graczyk, Amanda Crandall
Consumption of caffeinated beverages is associated with increased risk-taking behavior. The purpose of this study was to determine if acute caffeine administration influences risk-taking behavior in a dose-dependent manner. Participants were pre- (ages 8-9) and post-pubertal (ages 15-17) children who visited the laboratory three times and consumed a beverage containing 0, 1, or 2 mg/kg of caffeine. Thirty minutes later, participants completed the balloon analogue risk task (BART), the Iowa gambling task (IGT), and a delay discounting task...
February 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28195872/rethinking-our-definition-of-postoperative-success-a-comparative-analysis-of-three-upper-eyelid-retraction-repair-techniques-using-novel-metrics-to-capture-functional-and-aesthetic-outcomes
#5
Jacob A Evans, Thomas J E Clark, M Bridget Zimmerman, Richard C Allen, Jeffrey A Nerad, Keith D Carter, Erin M Shriver
PURPOSE: To compare 3 upper eyelid retraction repair techniques and introduce novel metrics, which enhance the analysis of postoperative aesthetic outcomes. METHODS: Retrospective review with Image J 1.48 digital analysis of patients who underwent repair of thyroid-related upper eyelid retraction at the University of Iowa from 1996 to 2014 via 1 of 3 surgical techniques, septum-opening levator recession with Muellerectomy, modified septum-preserving levator recession with Muellerectomy, and modified septum-preserving full-thickness blepharotomy, was conducted...
February 10, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28192123/comparative-genomic-analysis-of-the-iid-subtype-family-of-cryptosporidium-parvum
#6
Yaoyu Feng, Na Li, Dawn M Roellig, Alyssa Kelley, Guangyuan Liu, Said Amer, Kevin Tang, Longxian Zhang, Lihua Xiao
Host adaptation is known to occur in Cryptosporidium parvum, with IIa and IId subtype families preferentially infecting calves and lambs, respectively. To improve our understanding of the genetic basis of host adaptation in Cryptosporidium parvum, we sequenced the genomes of two IId specimens and one IIa specimen from China and Egypt using the Illumina technique and compared them with the published IIa IOWA genome. Sequence data were obtained for >99.3% of the expected genome. Comparative genomic analysis identified differences in numbers of three subtelomeric gene families between sequenced genomes and the reference genome, including those encoding SKSR secretory proteins, the MEDLE family of secretory proteins, and insulinase-like proteases...
February 10, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28174148/local-anesthesia-versus-local-anesthesia-and-conscious-sedation-for-inguinal-hernioplasty-protocol-of-a-randomized-controlled-trial
#7
Pierre-Anthony Leake, Patrick J Toppin, Marvin Reid, Joseph M Plummer, Patrick O Roberts, Hyacinth Harding-Goldson, Michael E McFarlane
BACKGROUND: Conscious sedation is regularly used in ambulatory surgery to improve patient outcomes, in particular patient satisfaction. Reports suggest that the addition of conscious sedation to local anesthesia for inguinal hernioplasty is safe and effective in improving patient satisfaction. No previous randomized controlled trial has assessed the benefit of conscious sedation in this regard. OBJECTIVE: To determine whether the addition of conscious sedation to local anesthesia improves patient satisfaction with inguinal hernioplasty...
February 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28168538/price-transparency-in-primary-care-can-patients-learn-about-costs-when-scheduling-an-appointment
#8
Brendan Saloner, Lisa Clemans Cope, Katherine Hempstead, Karin V Rhodes, Daniel Polsky, Genevieve M Kenney
BACKGROUND: Cost-sharing in health insurance plans creates incentives for patients to shop for lower prices, but it is unknown what price information patients can obtain when scheduling office visits. OBJECTIVE: To determine whether new patients can obtain price information for a primary care visit and identify variation across insurance types, offices, and geographic areas. DESIGN: Simulated patient methodology in which trained interviewers posed as non-elderly adults seeking new patient primary care appointments...
February 6, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28165925/molecular-detection-of-candidatus-bartonella-mayotimonensis-in-north-american-bats
#9
Thomas M Lilley, Cali A Wilson, Riley F Bernard, Emma V Willcox, Eero J Vesterinen, Quinn M R Webber, Laura Kurpiers, Jenni M Prokkola, Imran Ejotre, Allen Kurta, Kenneth A Field, DeeAnn M Reeder, Arto T Pulliainen
Candidatus Bartonella mayotimonensis was detected in 2010 from an aortic valve sample of a patient with endocarditis from Iowa, the United States of America. The environmental source of the potentially new endocarditis-causing Bartonella remained elusive. We set out to study the prevalence and diversity of bat-associated Bartonella in North America. During 2015, mist nets and harp traps were used to capture 92 bats belonging to two species: little brown myotis (Myotis lucifugus Le Conte 1831, n = 73) and the gray myotis (M...
February 6, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28160816/all-terrain-vehicle-safety-knowledge-riding-behaviors-and-crash-experience-of-farm-progress-show-attendees
#10
Charles A Jennissen, Karisa K Harland, Kristel Wetjen, Pamela Hoogerwerf, Lauren O'Donnell, Gerene M Denning
INTRODUCTION: Although all-terrain vehicles (ATVs) are very popular in rural areas for both recreation and work purposes, the epidemiology of agricultural ATV use remains largely unknown. METHODS: Farm Progress Show attendees in 2012 (Boone, Iowa) and 2013 (Decatur, Illinois) were surveyed about ATVs, including riding behaviors, crash history, and safety knowledge. Descriptive and comparative analyses were performed (N=635 surveys). RESULTS: Over half of those surveyed lived on a farm and more than 90% had ridden on an ATV...
February 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28160035/brexpiprazole-reduces-hyperactivity-impulsivity-and-risk-preference-behavior-in-mice-with-dopamine-transporter-knockdown-a-model-of-mania
#11
Morgane Milienne-Petiot, Mark A Geyer, Jørn Arnt, Jared W Young
RATIONALE: Bipolar disorder (BD) is a unique mood disorder defined by periods of depression and mania. The defining diagnosis of BD is the presence of mania/hypomania, with symptoms including hyperactivity and risk-taking. Since current treatments do not ameliorate cognitive deficits such as risky decision-making, and impulsivity that can negatively affect a patient's quality of life, better treatments are needed. OBJECTIVES: Here, we tested whether acute treatment with brexpiprazole, a serotonin-dopamine activity modulator with partial agonist activity at D2/3 and 5-HT1A receptors, would attenuate the BD mania-relevant behaviors of the dopamine transporter (DAT) knockdown mouse model of mania...
February 3, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28158316/phishing-suspiciousness-in-older-and-younger-adults-the-role-of-executive-functioning
#12
Brandon E Gavett, Rui Zhao, Samantha E John, Cara A Bussell, Jennifer R Roberts, Chuan Yue
Phishing is the spoofing of Internet websites or emails aimed at tricking users into entering sensitive information, with such goals as financial or identity theft. The current study sought to determine whether age is associated with increased susceptibility to phishing and whether tests of executive functioning can predict phishing susceptibility. A total of 193 cognitively intact participants, 91 younger adults and 102 older adults, were primarily recruited through a Psychology department undergraduate subject pool and a gerontology research registry, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28148663/pre-operative-functional-mobility-as-an-independent-determinant-of-inpatient-functional-recovery-after-total-knee-arthroplasty-during-three-periods-that-coincided-with-changes-in-clinical-pathways
#13
G van der Sluis, R A Goldbohm, J E Elings, M W Nijhuis-van der Sanden, R P Akkermans, R Bimmel, T J Hoogeboom, N L van Meeteren
AIMS: To investigate whether pre-operative functional mobility is a determinant of delayed inpatient recovery of activities (IRoA) after total knee arthroplasty (TKA) in three periods that coincided with changes in the clinical pathway. PATIENTS AND METHODS: All patients (n = 682, 73% women, mean age 70 years, standard deviation 9) scheduled for TKA between 2009 and 2015 were pre-operatively screened for functional mobility by the Timed-up-and-Go test (TUG) and De Morton mobility index (DEMMI)...
2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28146008/effect-of-surface-neuromuscular-electrical-stimulation-on-labial-and-lingual-muscles-in-healthy-volunteers
#14
Mohammed F Safi, Wilhelmina Wright-Harp, Jay R Lucker, Joan C Payne
: Neuromuscular electrical stimulation (NMES) may have potential as a treatment for muscle weakness as it may improve strength when applied to the orofacial muscles. However, before incorporating this procedure into clinical practice, research is needed to investigate its effects on lingual and facial muscles of speech and mastication. The aim of this study was to determine what effect(s) submental and labial NMES would have on lingual and labial muscle strength in healthy participants...
January 31, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28142356/iowa-dependent-adult-abuse-prosecutions-from-2006-through-2015
#15
Jeanette M Daly, Yinghui Xu, Gerald J Jogerst
BACKGROUND: In most states, health care providers are required to report abuse. Some states provide investigation feedback/findings to the reporter. The reporters rarely know if the perpetrator is convicted. The purposes of this study are to determine the incidence of Iowa dependent adult abuse prosecutions from 2006 through 2015, the incidence of convictions, and the association between dependent adult abuse prosecutions with county census and government characteristics. DESIGN AND METHODS: Through the Iowa Court Information Systems, dependent adult abuse prosecution data were purchased for a 10-year time period...
January 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28139260/efforts-of-a-unit-practice-council-to-implement-practice-change-utilizing-alcohol-impregnated-port-protectors-in-a-burn-icu
#16
Amy Martino, Leanna Thompson, Colleen Mitchell, Rachel Trichel, William Chappell, Justin Miller, David Allen, Elizabeth Mann-Salinas
BACKGROUND: Burn patients are an especially high-risk population for development of central line associated bloodstream infections (CLABSI) due to open wounds, extended length of intensive care unit stay, frequent use of central venous catheters, and generally immunocompromised state. Implementing evidence-based practices to prevent these infections is a 2014 National Patient Safety Goal per The Joint Commission. OBJECTIVES: The purpose of this project was introduction of a commercially available alcohol impregnated central venous line port protector to reduce the incidence of CLABSI in the burn unit...
January 27, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28138827/improving-receipt-and-preventive-care-delivery-for-adolescents-and-young-adults-initial-lessons-from-top-performing-states
#17
Claire D Brindis, Lauren Twietmeyer, M Jane Park, Sally Adams, Charles E Irwin
Purpose Provisions of the Patient Protection and Affordable Care Act (ACA) of 2010 hold promise for improving access to and receipt of preventive services for adolescents and young adults (AYAs). The Title V Block Grant transformation also includes a focus on improving adolescent preventive care. This brief report describes and discusses an inquiry of promising strategies for improving access and preventive care delivery identified in selected high-performing states. Methods Two data sources were used to identify top-performing states in insurance enrollment and preventive care delivery: National Survey of Children's Health for adolescents (ages 12-17 years) and Behavioral Risk Factors Surveillance System for young adults (ages 18-25 years)...
January 30, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28135485/breastfeeding-exposure-attitudes-and-intentions-of-african-american-and-caucasian-college-students
#18
Urmeka T Jefferson
BACKGROUND: African American mothers lag behind in breastfeeding initiation. Research is needed to gain an understanding of potential reasons for breastfeeding disparities. Research aim: This study explored breastfeeding exposure, attitudes, and intentions of African American and Caucasian college students by race and gender. METHODS: Women and men (696) attending college, who were younger than 45 years and without children, were included in this study. Survey data were collected using a demographic questionnaire and the Iowa Infant Feeding Attitude Scale...
February 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28135132/mercury-exposure-in-bald-eagles-admitted-for-rehabilitation-in-iowa-usa
#19
Julie A Blanchong, William J Reiter-Marolf, Stephen J Dinsmore
To gain insight into mercury exposure in Bald Eagles ( Haliaeetus leucocephalus ) in Iowa we collected blood from 22 rehabilitation eagles in 2012-13. The geometric mean blood mercury level was 0.144 μg/g (95% confidence interval: 0.066-0.314) and was at the lower end of the range of levels reported elsewhere.
January 30, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28129308/comparison-of-the-efficacy-and-safety-of-aripiprazole-versus-bupropion-augmentation-in-patients-with-major-depressive-disorder-unresponsive-to-selective-serotonin-reuptake-inhibitors-a-randomized-prospective-open-label-study
#20
Eun-Jin Cheon, Kwang-Hun Lee, Young-Woo Park, Jong-Hun Lee, Bon-Hoon Koo, Seung-Jae Lee, Hyung-Mo Sung
PURPOSE: The purpose of this study was to compare the efficacy and safety of aripiprazole versus bupropion augmentation in patients with major depressive disorder (MDD) unresponsive to selective serotonin reuptake inhibitors (SSRIs). METHODS: This is the first randomized, prospective, open-label, direct comparison study between aripiprazole and bupropion augmentation. Participants had at least moderately severe depressive symptoms after 4 weeks or more of SSRI treatment...
January 26, 2017: Journal of Clinical Psychopharmacology
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