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https://www.readbyqxmd.com/read/28927583/differences-in-decision-making-as-a-function-of-drug-of-choice
#1
REVIEW
Joshua L Gowin, Matthew E Sloan, Vijay A Ramchandani, Martin P Paulus, Scott D Lane
Poor decision-making is a central feature of all substance use disorders (SUD), but substances vary in the legal and health consequences associated with their use. For example, while the negative health consequences associated with cigarette smoking are often years away, the consequences of heroin abuse can be fatal in mere hours. It remains unclear if users of these substances show decision-making patterns that differ with the relative riskiness of their drug of choice. To address this question, we reviewed studies that compared decision-making of individuals using different substances...
September 18, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28927017/an-improved-evidential-iowa-sensor-data-fusion-approach-in-fault-diagnosis
#2
Yongchuan Tang, Deyun Zhou, Miaoyan Zhuang, Xueyi Fang, Chunhe Xie
As an important tool of information fusion, Dempster-Shafer evidence theory is widely applied in handling the uncertain information in fault diagnosis. However, an incorrect result may be obtained if the combined evidence is highly conflicting, which may leads to failure in locating the fault. To deal with the problem, an improved evidential-Induced Ordered Weighted Averaging (IOWA) sensor data fusion approach is proposed in the frame of Dempster-Shafer evidence theory. In the new method, the IOWA operator is used to determine the weight of different sensor data source, while determining the parameter of the IOWA, both the distance of evidence and the belief entropy are taken into consideration...
September 18, 2017: Sensors
https://www.readbyqxmd.com/read/28921673/safety-of-back-transfer-to-local-hospitals-during-an-acute-care-hospitalization
#3
Leah F Nelson, Karisa K Harland, Dan M Shane, Azeemuddin Ahmed, Nicholas M Mohr
PURPOSE: This paper investigates patient outcomes including length of stay (LOS), cost of hospitalization, bounce-back rates, transition to hospice care, and mortality, following back-transfer. METHODS: This study was an observational case-control study of adults hospitalized in Iowa between 2005 and 2013 to identify back-transferred patients. Back-transfer was defined as the transfer of rural patients near the end of their acute hospitalization in a comprehensive medical center back to a local community hospital for the completion of their medical care...
September 18, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28921575/ingested-nitrate-and-nitrite-disinfection-by-products-and-pancreatic-cancer-risk-in-postmenopausal-women
#4
Arbor J L Quist, Maki Inoue-Choi, Peter J Weyer, Kristin E Anderson, Kenneth P Cantor, Stuart Krasner, Laura E Beane Freeman, Mary H Ward, Rena R Jones
Nitrate and nitrite are precursors of N-nitroso compounds (NOC), probable human carcinogens that cause pancreatic tumors in animals. Disinfection by-products (DBP) exposures have also been linked with digestive system cancers, but few studies have evaluated relationships with pancreatic cancer. We investigated the association of pancreatic cancer with these drinking water contaminants and dietary nitrate/nitrite in a cohort of postmenopausal women in Iowa (1986-2011). We used historical monitoring and treatment data to estimate levels of long-term average nitrate and total trihalomethanes (TTHM; the sum of the most prevalent DBP class) and the duration exceeding one-half the maximum contaminant level (>½ MCL; nitrate-nitrogen 5mg/L, 40µg/L TTHM) among participants on public water supplies (PWS) >10 years...
September 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28918682/efficacy-of-technology-based-interventions-to-increase-the-use-of-hearing-protections-among-adolescent-farmworkers
#5
Khalid M Khan, Sydney S Evans, Sylvanna L Bielko, Diane S Rohlman
OBJECTIVE: Adolescent farmworkers are exposed to loud noise during farm activities. We present a prospective study that evaluated the efficacy of low-cost, technology-based intervention approaches in high schools to enhance the use of hearing protection among adolescent farmworkers. DESIGN: Six high schools in Iowa that agreed to participate in the study were divided into three equal groups through cluster-randomisation with each group receiving one of the three formats of hearing protection intervention: (a) classroom training, (b) classroom training coupled with smartphone app training and (c) computer training...
September 18, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28915225/physical-activity-not-sedentary-time-predicts-dual-energy-x-ray-absorptiometry-measured-adiposity-age-5-to-19-years
#6
Kathleen F Janz, Piroska Boros, Elena M Letuchy, Soyang Kwon, Trudy L Burns, Steven M Levy
PURPOSE: To examine the associations among physical activity (PA), sedentary time (SED), and TV viewing (TV) with fat mass (FAT) and visceral adipose tissue mass (VAT) from childhood through adolescence (5-19 yr). METHODS: Participants in the Iowa Bone Development Study (n = 230 males and 233 females) were examined at ages 5, 8, 11, 13, 15, 17, and 19 yr. Accelerometers measured moderate- or vigorous-intensity PA (MVPA; min·d), light-intensity PA (LPA; min·d), and SED (h·d)...
October 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28913416/using-focused-laboratory-management-and-quality-improvement-projects-to-enhance-resident-training-and-foster-scholarship
#7
Matthew D Krasowski, Bradley A Ford, J Stacey Klutts, Chris S Jensen, Angela S Briggs, Robert A Robinson, Leslie A Bruch, Nitin J Karandikar
Training in patient safety, quality, and management is widely recognized as an important element of graduate medical education. These concepts have been intertwined in pathology graduate medical education for many years, although training programs face challenges in creating explicit learning opportunities in these fields. Tangibly involving pathology residents in management and quality improvement projects has the potential to teach and reinforce key concepts and further fulfill Accreditation Council for Graduate Medical Education goals for pursuing projects related to patient safety and quality improvement...
January 2017: Acad Pathol
https://www.readbyqxmd.com/read/28901229/intraoperative-high-frequency-jet-ventilation-is-equivalent-to-conventional-ventilation-during-patent-ductus-arteriosus-ligation
#8
Mackenzie Noonan, Joseph W Turek, John M Dagle, Steven J McElroy
BACKGROUND: Patent ductus arteriosus (PDA) treatment is typically pharmacologic, but if unsuccessful, surgical ligation is commonly performed. High-frequency jet ventilation (HFJV) is used at the University of Iowa Stead Family Children's Hospital for extremely low birth weight infants. Historically, neonates requiring PDA ligation were temporarily transferred to conventional ventilation (CV) prior to surgery. OBJECTIVE: The objective of this study was to determine whether conversion was necessary...
September 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28899305/writing-from-the-edge
#9
Nan Russell Yancey
On the 30th Anniversary of Nursing Science Quarterly, the 17-year journey of conceiving, launching, and guiding the "Teaching-Learning Column" was explored in this dialogue with Dr. Sandra Schmidt Bunkers, adjunct professor of nursing, South Dakota State University Brookings, South Dakota, founding contributing editor of the column, and Dr. Barbara Backer Condon, Professor of Nursing, Briar Cliff University, Sioux City, Iowa, contributing editor, 2012-2016. Reflecting on the shared stories, the challenge is offered to continue the tradition of the column in reading, writing, and thinking from the edge, to bravely consider what might be, daring to go beyond the confinements of mainstream thinking, and to vision as yet unimagined possibilities in teaching-learning in nursing...
January 2017: Nursing Science Quarterly
https://www.readbyqxmd.com/read/28898051/effect-of-alzheimer-familial-chromosomal-mutations-on-the-amyloid-fibril-interaction-with-different-pet-tracers-insight-from-molecular-modeling-studies
#10
Kanagasabai Balamurugan, Natarajan Arul Murugan, Bengt Långström, Agneta Nordberg, Hans Ågren
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Along with an increasing number of elderly worldwide it poses a great challenge for the society and healthcare. Although sporadic AD is the common form of AD, 2-3% of the AD cases are expected to be due to mutations in the beta region of the amyloid precursor protein which is referred to as autosomal dominant AD (ADAD). These mutations may cause changes in the secondary structure of the amyloid beta fibrils and may alter the fibrillization rate leading to changes in the disease development and could also affect the binding to tracers used in diagnosis...
September 12, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28889017/mycoplasmas-brain-invaders
#11
REVIEW
Rubén S Rosales, Roberto Puleio, Guido R Loria, Salvatore Catania, Robin A J Nicholas
Mycoplasmas of humans and animals are usually associated with respiratory, autoimmune, genital and joint diseases. Human mycoplasmas have also been known to affect the brain. Severe central nervous system (CNS) diseases, such as encephalitis, have been linked to Mycoplasma pneumoniae and ureaplasma infections. Less well known is the sheep and goat pathogen, Mycoplasma agalactiae, which has been found in large quantities in the brain where it may be responsible for non-purulent encephalitis as well as ataxia in young animals...
September 5, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28888599/management-operational-animal-health-and-economic-characteristics-of-large-dairy-herds-in-4-states-in-the-upper-midwest-of-the-united-states
#12
T L Evink, M I Endres
Recent trends in dairy farm structure in the United States have included a decreasing number of farms, although farm size has increased, especially the share of milk production from very large herds (>2,500 cows). The objectives of this observational study were to describe common management practices; to characterize labor and operational structure; to measure some aspects of animal health, including lameness, hock lesions, mortality, and mastitis incidence; and to summarize cost of production on farms with more than 2,500 cows in 4 states in the Upper Midwest of the United States...
September 6, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28887899/the-anterior-insula-bidirectionally-modulates-cost-benefit-decision-making-on-a-rodent-gambling-task
#13
M L Daniel, P J Cocker, J Lacoste, A C Mar, J L Houeto, A Belin-Rauscent, D Belin
Deficits in cost-benefit decision making, as assessed in the Iowa Gambling Task (IGT), are commonly observed in neuropsychiatric disorders such as addiction. There is considerable variation in the maximisation of rewards on such tasks, both in the general population and in rodent models, suggesting individual differences in decision making may represent a key endophenotype for vulnerability to neuropsychiatric disorders. Increasing evidence suggests that the insular cortex, which is involved in interoception and emotional processes in humans, may be a key neural locus in the control of decision making processes...
September 9, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28887373/optical-coherence-tomography-identifies-outer-retina-thinning-in-frontotemporal-degeneration
#14
Benjamin J Kim, David J Irwin, Delu Song, Ebenezer Daniel, Jennifer D Leveque, Aaishah R Raquib, Wei Pan, Gui-Shuang Ying, Tomas S Aleman, Joshua L Dunaief, Murray Grossman
OBJECTIVE: Whereas Alzheimer disease (AD) is associated with inner retina thinning visualized by spectral-domain optical coherence tomography (SD-OCT), we sought to determine if the retina has a distinguishing biomarker for frontotemporal degeneration (FTD). METHODS: Using a cross-sectional design, we examined retinal structure in 38 consecutively enrolled patients with FTD and 44 controls using a standard SD-OCT protocol. Retinal layers were segmented with the Iowa Reference Algorithm...
September 8, 2017: Neurology
https://www.readbyqxmd.com/read/28886597/pesticide-use-and-age-related-macular-degeneration-in-the-agricultural-health-study
#15
Martha P Montgomery, Eric Postel, David M Umbach, Marie Richards, Mary Watson, Aaron Blair, Honglei Chen, Dale P Sandler, Silke Schmidt, Freya Kamel
BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness in developed countries. Few studies have investigated its relationship to environmental neurotoxicants. In previous cross-sectional studies, we found an association between pesticide use and self-reported retinal degeneration. OBJECTIVE: We evaluated the association of pesticide use with physician-confirmed incident AMD. METHODS: The Agricultural Health Study (AHS) is a prospective cohort of pesticide applicators and their spouses enrolled from 1993-1997 in Iowa and North Carolina...
July 19, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28885427/safety-of-medical-abortion-provided-through-telemedicine-compared-with-in-person
#16
Daniel Grossman, Kate Grindlay
OBJECTIVE: To compare the proportion of medical abortions with a clinically significant adverse event among telemedicine and in-person patients at a clinic system in Iowa during the first 7 years of the service. METHODS: We conducted a retrospective cohort study. We analyzed data on clinically significant adverse events (hospital admission, surgery, blood transfusion, emergency department treatment, and death) for all medical abortions performed by telemedicine or in person at a clinic system in Iowa between July 1, 2008, and June 30, 2015...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28884829/preventive-dental-care-among-medicaid-enrolled-senior-adults-from-community-to-nursing-facility-residence
#17
Mary C Kelly, Daniel J Caplan, Mercedes Bern-Klug, Howard J Cowen, Marsha A Cunningham-Ford, Leonardo Marchini, Elizabeth T Momany
OBJECTIVE: The primary objective of this study was to determine whether the utilization rate of preventive oral health care services while senior adults were community-dwelling differed from the rate after those same senior adults were admitted to nursing facilities. A secondary objective was to evaluate other significant predictors of receipt of preventive oral health procedures after nursing facility entry. METHODS: Iowa Medicaid claims from 2007-2014 were accessed for adults who were 68+ years upon entry to a nursing facility and continuously enrolled in Medicaid for at least three years before and at least two years after admission (n = 874)...
September 8, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28883621/assessing-the-potential-for-raw-meat-to-influence-human-colonization-with-staphylococcus-aureus
#18
Margaret Carrel, Chang Zhao, Dipendra Thapaliya, Patrick Bitterman, Ashley E Kates, Blake M Hanson, Tara C Smith
The role of household meat handling and consumption in the transfer of Staphylococcus aureus (S. aureus) from livestock to consumers is not well understood. Examining the similarity of S. aureus colonizing humans and S. aureus in meat from the stores in which those individuals shop can provide insight into the role of meat in human S. aureus colonization. S. aureus isolates were collected from individuals in rural and urban communities in Iowa (n = 3347) and contemporaneously from meat products in stores where participants report purchasing meat (n = 913)...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28877026/effectiveness-of-a-third-dose-of-mmr-vaccine-for-mumps-outbreak-control
#19
Cristina V Cardemil, Rebecca M Dahl, Lisa James, Kathleen Wannemuehler, Howard E Gary, Minesh Shah, Mona Marin, Jacob Riley, Daniel R Feikin, Manisha Patel, Patricia Quinlisk
BACKGROUND: The effect of a third dose of the measles-mumps-rubella (MMR) vaccine in stemming a mumps outbreak is unknown. During an outbreak among vaccinated students at the University of Iowa, health officials implemented a widespread MMR vaccine campaign. We evaluated the effectiveness of a third dose for outbreak control and assessed for waning immunity. METHODS: Of 20,496 university students who were enrolled during the 2015-2016 academic year, mumps was diagnosed in 259 students...
September 7, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28875136/maximal-strength-and-endurance-scores-of-the-tongue-lip-and-cheek-in-healthy-normal-koreans
#20
Dong-Min Jeong, Yoo-Jin Shin, Na-Ra Lee, Ho-Kyung Lim, Han-Wool Choung, Kang-Mi Pang, Bong-Ju Kim, Soung-Min Kim, Jong-Ho Lee
OBJECTIVES: The purpose of this study was to establish normative data for healthy Korean adults by measuring the maximal strength and endurance scores of the tongue, lip, and cheek, and to examine correlations between these measurements. MATERIALS AND METHODS: This study included 120 subjects that were divided into three groups according to age: young (20-39 years), middle-aged (40-59 years), and older (over 60 years); and by gender. Measurements were taken using the Iowa Oral Performance Instrument (IOPI)...
August 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
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