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https://www.readbyqxmd.com/read/29451444/survival-and-prognostic-factors-in-cats-with-restrictive-cardiomyopathy-a-review-of-90-cases
#1
Chiara Locatelli, Danitza Pradelli, Giulia Campo, Ilaria Spalla, Alice Savarese, Paola G Brambilla, Claudio Bussadori
Objectives Large studies focusing on restrictive cardiomyopathy (RCM) in the cat are scarce. The aims of this retrospective study were to describe epidemiological characteristics and to analyse prognostic factors affecting survival in cats with RCM. Methods The clinical archives of the Gran Sasso Veterinary Clinic (Milan, Italy) and of the cardiology unit of the Department of Veterinary Medicine (University of Milan, Italy) from 1997-2015 were reviewed for all cats diagnosed with RCM based on an echocardiographic examination (left atrial/bi-atrial enlargement, normal left ventricle wall thickness, normal or mildly decreased systolic function and restrictive left ventricle filling pattern with pulsed Doppler echocardiography)...
February 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29445015/influence-of-ageing-on-quantitative-contrast-enhanced-ultrasound-of-the-kidneys-in-healthy-cats
#2
Emmelie Stock, Dominique Paepe, Sylvie Daminet, Luc Duchateau, Jimmy H Saunders, Katrien Vanderperren
The degenerative effects of ageing on the kidneys have been extensively studied in humans. However, only recently interest has been focused on renal ageing in veterinary medicine. Contrast-enhanced ultrasound allows non-invasive evaluation of renal perfusion in conscious cats. Renal perfusion parameters were obtained in 43 healthy cats aged 1-16 years old, and the cats were divided in four age categories: 1-3 years, 3-6 years, 6-10 years and over 10 years. Routine renal parameters as serum creatinine, serum urea, urine-specific gravity, urinary protein:creatinine ratio and systolic blood pressure were also measured...
February 14, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29408407/antimicrobial-susceptibility-survey-on-bacterial-agents-of-canine-and-feline-urinary-tract-infections-weight-of-the-empirical-treatment
#3
Elisa Rampacci, Marco Bottinelli, Valentina Stefanetti, Doreene R Hyatt, Elisa Sgariglia, Mauro Coletti, Fabrizio Passamonti
OBJECTIVES: This work characterizes the antimicrobial susceptibility of uropathogens isolated from empirically treated dogs and cats. Within-household transmission of uropathogens can involve humans and companion animals. Knowledge on the prevalence and susceptibility pattern of isolates from canine and feline urine samples and the impact of prior antimicrobial treatment is important to prevent the dissemination of antimicrobial resistance. METHODS: A retrospective study was conducted selecting antibiotically treated companion animals...
February 3, 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29399138/lymphadenitis-associated-with-cat-scratch-disease-simulating-a-neoplasm-imaging-findings-with-histopathological-associations
#4
Ying Chen, Yan-Biao Fu, Xiu-Fang Xu, Yao Pan, Chen-Ying Lu, Xiu-Liang Zhu, Qing-Hai Li, Ri-Sheng Yu
The lymphadenitis associated with cat-scratch disease (CSD) is often confused with neoplasms by a number of radiologists and clinicians, and consequently, unnecessary invasive procedures or surgeries are performed. In the present study, the contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) findings of 10 patients (6 men and 4 women) with clinically and pathologically confirmed lymphadenitis associated with CSD were retrospectively analyzed (CT in 3 patients, MRI in 6 patients, and CT and MRI in 1 patient) at The Second Affiliated Hospital of Zhejiang University School of Medicine (Hangzhou, China) between January 2007 and November 2014...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29398100/vertical-or-horizontal-diagnosing-and-treating-cats-who-urinate-outside-the-box
#5
REVIEW
Leticia Mattos de Souza Dantas
Feline elimination problems are commonly presented to general practitioners and behavioral medicine specialists. The correct diagnosis is often missed by veterinarians owing to individual variation and multifactorial cases. Three diagnostic umbrellas need to be considered: medical problems, toileting behavior outside of the litter box, and urine marking. The treatment plan for most cases, regardless of etiology, involves optimum litter box management, fulfilling cats' environmental needs, stress reduction, behavior therapy techniques, and trigger removal...
February 2, 2018: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29353423/polymerase-chain-reaction-based-detection-of-myc-transduction-in-feline-leukemia-virus-infected-cats
#6
Ryosuke Sumi, Ariko Miyake, Taiji Endo, Yoshiharu Ohsato, Minh Ha Ngo, Kazuo Nishigaki
Feline lymphomas are associated with the transduction and activation of cellular proto-oncogenes, such as c-myc, by feline leukemia virus (FeLV). We describe a polymerase chain reaction assay for detection of myc transduction usable in clinical diagnosis. The assay targets c-myc exons 2 and 3, which together result in a FeLV-specific fusion gene following c-myc transduction. When this assay was conducted on FeLV-infected feline tissues submitted for clinical diagnosis of tumors, myc transduction was detected in 14% of T-cell lymphoma/leukemias...
January 20, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29353203/the-water-extract-of-tutsan-hypericum-androsaemum-l-red-berries-exerts-antidepressive-like-effects-and-in-vivo-antioxidant-activity-in-a-mouse-model-of-post-stroke-depression
#7
Seyed Mohammad Nabavi, Seyed Fazel Nabavi, Antoni Sureda, Giovanni Caprioli, Romilde Iannarelli, Arold Jorel Tsetegho Sokeng, Nady Braidy, Sedigheh Khanjani, Akbar Hajizadeh Moghaddam, Atanas G Atanasov, Maria Daglia, Filippo Maggi
Hypericum androsaemum L., commonly known as 'tutsan' or 'shrubby St. John's Wort', is a member of the Hypericum genus found growing spontaneously in the Mediterranean area and is cultivated extensively as an ornamental plant due to the showy color variation in its fresh berry-like capsules, which turn from red to shiny black as they ripen. Tutsan has also been used in Portuguese and Spanish folk medicine to treat depression. In this study, we assessed the beneficial role of the water extract of H. androsaemum red berries (WE) in an experimental animal model of post-stroke depression...
January 16, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29351945/concurrent-endocrine-neoplasias-in-dogs-and-cats-a-retrospective-study-2004-2014
#8
Laura Beatrice, Felicitas Schär Boretti, Nadja S Sieber-Ruckstuhl, Claudia Mueller, Claudia Kümmerle-Fraune, Monika Hilbe, Paula Grest, Claudia E Reusch
Multiple endocrine neoplasia (MEN) is a well-known syndrome in human medicine, whereas only a few cases of concurrent endocrine neoplasias have been reported in dogs and cats. The aim of this study was to evaluate the prevalence of concurrent endocrine neoplasias in dogs and cats at our clinic, identify possible breed and sex predispositions and investigate similarities with MEN syndromes in humans. Postmortem reports of 951 dogs and 1155 cats that died or were euthanased at the Clinic for Small Animal Internal Medicine, University of Zurich, between 2004 and 2014 were reviewed, and animals with at least two concurrent endocrine neoplasias and/or hyperplasias were included...
January 19, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29318026/broncholithiasis-associated-with-lower-airway-inflammation-and-subsequent-pyothorax-in-a-cat
#9
Ferran Valls Sanchez, Jennifer Stewart, Catherine Bovens, Jordi Puig
Case summary: A 12-year-old female spayed domestic shorthair cat presented with history of a long-term chronic cough that had worsened during the previous 2 months. Thoracic radiographs revealed numerous mineral opacities throughout the lung fields. Multiple bronchial plugs of pale yellow material were present on bronchoscopy, consistent with broncholithiasis. Bronchoalveolar lavage cytology revealed a mild neutrophilic inflammation and bacterial culture was negative. The cat was diagnosed with chronic inflammatory lower airway disease and broncholithiasis, suspected to be due to mineralisation of secretions in the bronchial lumen...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29316974/protective-effects-of-mentha-piperita-l-leaf-essential-oil-against-ccl4-induced-hepatic-oxidative-damage-and-renal-failure-in-rats
#10
Khaled Bellassoued, Anis Ben Hsouna, Khaled Athmouni, Jos van Pelt, Fatma Makni Ayadi, Tarek Rebai, Abdelfattah Elfeki
BACKGROUND: Mentha piperita L. is a flowering plant belonging to the Lamiaceae family. Mentha plants constitute one of the main valuable sources of essential oil used in foods and for medicinal purposes. METHODS: The present study aimed to investigate the composition and in vitro antioxidant activity of Mentha piperita leaf essential oil (MpEO). A single dose of CCl4 was used to induce oxidative stress in rats, which was demonstrated by a significant rise of serum enzyme markers...
January 9, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29314873/2018-aaha-diabetes-management-guidelines-for-dogs-and-cats
#11
Ellen Behrend, Amy Holford, Patty Lathan, Renee Rucinsky, Rhonda Schulman
Diabetes mellitus (DM) is a common disease encountered in canine and feline medicine. The 2018 AAHA Diabetes Management Guidelines for Dogs and Cats revise and update earlier guidelines published in 2010. The 2018 guidelines retain much of the information in the earlier guidelines that continues to be applicable in clinical practice, along with new information that represents current expert opinion on controlling DM. An essential aspect of successful DM management is to ensure that the owner of a diabetic dog or cat is capable of administering insulin, recognizing the clinical signs of inadequately managed DM, and monitoring blood glucose levels at home, although this is ideal but not mandatory; all topics that are reviewed in the guidelines...
January 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29307121/fleas-of-dog-and-cat-species-biology-and-flea-borne-diseases
#12
REVIEW
Filomena Iannino, Nadia Sulli, Antonio Maitino, Ilaria Pascucci, Guglielmo Pampiglione, Stefania Salucci
Ectoparasitic insects play a major role in veterinary medicine. Fleas infest man and animals and are the most frequent external parasites of companion animals worldwide. Some species are known to be vectors of zoonotic pathogens. Dogs and cats may play an important role either as reservoir of some of the pathogens or as transport vehicles for infected eas between their natural reservoirs and human beings, thus playing a crucial step in the transmission cycle of ea-borne diseases. This article reviews relevant literature on morphology, classi cation, host speci city, geographical distribution, and seasonality of eas infesting dogs and cats in order to improve their timely identi cation, prevention, and control...
December 29, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/29306510/protective-effects-of-artemisia-campestris-extract-against-gastric-acid-reflux-induced-esophageal-mucosa-injuries
#13
Mohamed-Amine Jabri, Haifa Tounsi, Afifa Abdellaoui, Lamjed Marzouki, Hichem Sebai
Artemisia campestris L. has been widely used in alternative medicine to treat digestive system diseases, particularly gastroesophageal disorders. In the present investigation, we studied the putative protective effect of Artemisia campestris aqueous extract (ACAE) against gastro-esophageal reflux (GER)-induced esophagitis in rats. The experimental ophagitis was induced by the ligation of the pylorus as well as the junction between the forestomach and the corpus. We firstly found that ACAE administration at 100, 200 and 400 mg/kg, b...
January 2, 2018: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/29283239/diabetes-from-the-origins-of-the-problem-to-the-nobel-prize-bioethics
#14
R A Kopaladze
Analysis of scientific works from the creation of an experimental model of diabetes before discovery insulin was done. Emphasized is the priority of the Russian pathologist L. W. Sobolew (1876-1919) in the discovery of the endocrine function of the pancreas in experimental animals - rabbits, dogs, cats. In 1923 Canadian scientists Banting and Macleod were awarded the Nobel prize for the discovery of insulin. However, the methods and the idea of Nobel laureates were the same that had been developed 20 years earlier by the Russian scientists...
January 2017: Uspekhi Fiziologicheskikh Nauk
https://www.readbyqxmd.com/read/29277718/effect-of-allantoin-on-experimentally-induced-gastric-ulcers-pathways-of-gastroprotection
#15
Dayane Moreira da Silva, José Luís Rodrigues Martins, Danillo Ramos de Oliveira, Iziara Ferreira Florentino, Daiany Priscilla Bueno da Silva, Fernanda Cristina Alcântara Dos Santos, Elson Alves Costa
Gastric ulcer affects people worldwide, and its inefficacy and recurrence have fueled the search for new therapeutic strategies. Despite the well-known use of allantoin in medicines and cosmetic products, its effect has not yet been studied with regard to gastric ulcer. Hence, the aim of the present study was to explore the pharmaco-mechanistic efficacy of allantoin against commonly harmful agents that cause injuries to the stomach. Ethanol, indomethacin, and stress-induced gastric ulcer models were adopted, in addition to pylorus ligature, a quantification of vascular permeability, glutathione (GSH), gastric adhered mucus, prostaglandin (PGE2), pro-inflammatory cytokines levels, myeloperoxidase (MPO), and catalase (CAT) activities...
December 22, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29277609/ra-xii-exerts-anti-oxidant-and-anti-inflammatory-activities-on-lipopolysaccharide-induced-acute-renal-injury-by-suppressing-nf-%C3%AE%C2%BAb-and-mapks-regulated-by-ho-1-nrf2-pathway
#16
Xusheng An, Futai Shang
Acute kidney injury (AKI) is an abrupt loss of kidney function and severe AKI needs renal replacement therapeutic strategy and has high mortality. RA-XII is a natural cyclopeptide, isolated from the traditional Chinese medicine Rubia yunnanensis, exerting anti-inflammatory and anti-tumor activities. The present study aimed to explore the effects of RA-XII on LPS-induced ACI and the underlying molecular mechanism in TCMK-1 cells in vitro. The results indicated that RA-XII delayed the animal death caused by LPS in mice...
December 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29277608/triptolide-induced-hepatotoxicity-can-be-alleviated-when-combined-with-panax-notoginseng-saponins-and-catapol
#17
Lingling Zhou, Cong Zhou, Zhe Feng, Zhangpu Liu, Huaxu Zhu, Xueping Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: The hepatotoxicity of Tripterygium wilfordii Hook. f. (TW), due to the presence of triptolide (TP), limits its therapeutic potential. Based on the traditional Chinese medicine theory, the theory of "Yi lei xiang zhi" was proposed that Chinese herbs with different efficacy can restrict each other to achieve the least adverse reactions. AIM OF THE STUDY: To observe the effects of Catapol (CAT) and Panax notoginseng saponins (PNS), active ingredients in Rehmannia glutinosa (RG) and Panax notoginseng (PN) respectively, on reducing TP-induced hepatotoxicity, and further to explore the mechanisms...
December 22, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29250976/attenuation-of-brain-mitochondria-oxidative-damage-by-albizia-julibrissin-durazz-neuroprotective-and-antiemetic-effects
#18
Mohammad Ali Ebrahimzadeh, Hamed Fathi, Ali Ziar, Hamidreza Mohammadi
Medicinal plants, as new drugs, are considered for treatment of insomnia, anxiety, depression, confusion, nausea, and vomiting symptoms. The current study aimed to evaluate the neuroprotective and antiemetic effects of Albizia. julibrissin Durazz. flower extract in the chickens. Emesis was induced by copper sulfate and ipecac (60 and 600 mg/kg, orally, respectively) and the methanolic extract (50, 100, and 200 mg/kg) were injected intraperitoneally (i.p.). Mitochondrial function, lipid peroxidation (LPO), protein carbonyl (PC) content, and catalase activity as biomarkers of oxidative damage were evaluated in the brain mitochondria...
December 18, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29249988/stemodia-maritima-l-extract-decreases-inflammation-oxidative-stress-and-alveolar-bone-loss-in-an-experimental-periodontitis-rat-model
#19
Alrieta H Teixeira, Jordânia M de Oliveira Freire, Luzia H T de Sousa, Antônia T Parente, Nayara A de Sousa, Angela M C Arriaga, Francisca R Lopes da Silva, Iracema M Melo, Igor I Castro da Silva, Karuza M A Pereira, Paula Goes, José J do Nascimento Costa, Gerardo Cristino-Filho, Vicente de Paulo T Pinto, Hellíada V Chaves, Mirna M Bezerra
Periodontitis is very prevalent worldwide and is one of the major causes of tooth loss in adults. About 80% of the worldwide population use medicinal plants for their health care. Stemodia maritima L. (S. maritima) antioxidant and antimicrobial effects in vitro as well as anti-inflammatory properties. Herein, the potential therapeutic effect of S. maritima was assessed in rats subjected to experimental periodontitis (EP). EP was induced in female Wistar rats by nylon thread ligature around 2nd upper left molars for 11 days...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29248593/phototoxic-effect-of-oxytetracycline-on-normal-human-melanocytes
#20
Jakub Rok, Dorota Wrześniok, Artur Beberok, Michał Otręba, Marcin Delijewski, Ewa Buszman
Oxytetracycline is a broad-spectrum antibiotic, used in dermatology and veterinary medicine. Like other tetracyclines, it may evoke skin phototoxic reactions related to generation of reactive oxygen species (ROS). Melanins are biopolymers synthesised in melanocytes - highly specialised cells, localised in the basal layer of epidermis. Production of melanin is a defence mechanism against harmful effects of UV radiation, ROS and many chemical substances, including drugs. In the present study the influence of oxytetracycline and UVA radiation on darkly pigmented melanocytes viability, the melanogenesis process and the activity of antioxidant enzymes were analysed...
December 14, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
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