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https://www.readbyqxmd.com/read/29685450/motivators-and-barriers-for-dog-and-cat-owners-and-veterinary-surgeons-in-the-united-kingdom-to-using-preventative-medicines
#1
Zoe Belshaw, Natalie J Robinson, Rachel S Dean, Marnie L Brennan
Routine use of preventative medicines is advocated as part of responsible dog and cat ownership. However, it has been suggested that the number of owners in the United Kingdom (UK) using preventative medicines to protect their pets is in decline. The aim of this novel study was to use a qualitative methodology to explore the attitudes of pet owners and veterinary surgeons in the UK to using preventative medicine products in dogs and cats. Preventative medicine was defined as "a drug or any other preparation used to prevent disease, illness or injury...
June 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29678910/serotype-diversity-and-antimicrobial-resistance-among-salmonella-enterica-isolated-from-patients-at-an-equine-referral-hospital
#2
I M Leon, S D Lawhon, K N Norman, D S Threadgill, N Ohta, J Vinasco, H M Scott
Although Salmonella enterica can produce life-threatening colitis in horses, certain serotypes are more commonly associated with clinical disease. Our aim was to evaluate the proportional morbidity attributed to different serotypes, as well as phenotypic and genotypic antimicrobial resistance (AMR) of Salmonella isolated from patients at an equine referral hospital in the southern United States. Two-hundred-fifty-five Salmonella isolates were obtained from clinical samples of patients admitted to the hospital between 2007 and 2015...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29670663/the-effect-of-sanggua-drink-extract-on-insulin-resistance-through-the-pi3k-akt-signaling-pathway
#3
Yu Cai, Ying Wang, Fei Zhi, Qi-Chang Xing, Yun-Zhong Chen
Treating type 2 diabetes mellitus (T2DM) using thiazolidinediones and biguanides can present several challenges for patients. Sanggua Drink (SGD) is a commonly used agent in traditional Chinese medicine, and it consists of Folium Mori , Fructus Momordicae Charantiae , Radix Puerariae Lobatae , and Rhizoma Dioscorea . The hypoglycemic effects and mechanisms of SGD extracts on insulin resistance in diabetic rats were investigated. SGD (1.24 g/kg orally) was verified in T2DM rats induced by a high-fat diet and streptozotocin...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29662886/high-prevalence-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-among-clinical-isolates-from-cats-and-dogs-admitted-to-a-veterinary-hospital-in-switzerland
#4
Anna Lena Zogg, Sabrina Simmen, Katrin Zurfluh, Roger Stephan, Sarah N Schmitt, Magdalena Nüesch-Inderbinen
Objectives: This study aimed to identify and characterize extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae among clinical samples of companion animals. Methods: A total of 346 non-duplicate Enterobacteriaceae isolates were collected between 2012 and 2016 from diseased cats ( n  = 115) and dogs ( n  = 231). The presence of bla ESBL , PMQR genes, and the azithromycin resistance gene mph(A) was confirmed by PCR and sequencing of bla genes...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29660468/ethyl-acetate-fraction-of-trichilia-catigua-protects-against-oxidative-stress-and-neuroinflammation-after-cerebral-ischemia-reperfusion
#5
Jacqueline Godinho, Anacharis Babeto de Sa-Nakanishi, Lucas Stafuza Moreira, Rúbia Maria Weffort de Oliveira, Claudia Hitomi Huzita, João Carlos P Mello, André Oliveira Fernandes da Silva, Celso Vataru Nakamura, Isolde Santos Previdelli, Matheus Henrique Dal Molin Ribeiro, Humberto Milani
ETHNOPHARMACOLOGICAL RELEVANCE: Trichilia catigua A. Juss (Meliaceae) preparations have been used in folk medicine to alleviate fatigue, stress, and improve memory. Antinociceptive, antiinflammatory, and in vitro neuroprotective effects have been observed in animals. Cerebral ischemia/reperfusion (I/R) leads to severe neuropsychological deficits that are largely associated with oxidative stress, inflammation and neurodegeneration. We reported previously that an ethyl-acetate fraction (EAF) of T...
April 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29655479/update-on-cancer-treatment-in-exotics
#6
REVIEW
Ashley Zehnder, Jennifer Graham, Gunther Antonissen
Treatment options for animals with cancer are rapidly expanding, including in exotic animal medicine. Limited information is available about treatment effects in exotic pet species beyond individual case reports. Most cancer treatment protocols in exotic animals are extrapolated from those described in humans, dogs, and cats. This review provides an update on cancer treatment in exotic animal species. The Exotic Species Cancer Research Alliance accumulates clinical cases in a central location with standardized clinical information, with resources to help clinicians find and enter their cases for the collective good of exotic clinicians and their patients...
May 2018: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/29649320/strychnos-pseudoquina-modulates-the-morphological-reorganization-of-the-scar-tissue-of-second-intention-cutaneous-wounds-in-rats
#7
Mariáurea Matias Sarandy, Lyvia Lopes Miranda, Luciana Schulthais Altoé, Rômulo Dias Novaes, Virgínia Vinha Zanuncio, João Paulo Viana Leite, Reggiani Vilela Gonçalves
Natural substances are used in folk medicines to treat injuries. Strychnos pseudoquina has scarring, antipyretic, and antimalarial actions. The present study aimed to analyze the effect of S. pseudoquina on cutaneous wound healing in rats. The S. pseudoquina extract was submitted to phytochemical prospection. The levels of flavonoids and total phenolic compounds in the extract were 50.7 mg/g and 2.59 mg/g, respectively. Thirty Wistar rats were individualized in cages with food and water ad libitum (registration no...
2018: PloS One
https://www.readbyqxmd.com/read/29625223/antioxidant-and-hepatoprotective-effects-of-intracellular-mycelium-polysaccharides-from-pleurotus-geesteranus-against-alcoholic-liver-diseases
#8
Xinling Song, Qiang Shen, Min Liu, Chen Zhang, Lan Zhang, Zhenzhen Ren, Wenshuai Wang, Yuhan Dong, Xiuxiu Wang, Jianjun Zhang, Le Jia
In the present study, we investigated the antioxidant and hepatoprotective effects of intracellular mycelium polysaccharides from Pleurotus geesteranus (IMPP) to address acute alcoholic liver diseases (ALD). Animal studies have demonstrated that the hepatic parameters of CYP2E1, MPO, TC, ALT, AST and ALP, HDLC, LDL-C and VLDL-C were improved; the inflammatory factor levels, including TNF-α, IL-1β and IL-6, were decreased; the hepatic ADH and ALDH activities were inhibited; the activities of the antioxidant enzymes SOD, GSH-Px, CAT and T-AOC were enhanced; and the MDA and LPO contents were reduced by IMPP treatment...
April 3, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29623690/observation-about-phosphorus-and-protein-supply-in-cats-and-dogs-prior-to-the-diagnosis-of-chronic-kidney-disease
#9
L F Böswald, E Kienzle, B Dobenecker
There is evidence that nutritional phosphorus (P) excess may be a risk factor for chronic kidney disease (CKD) in humans and pets (Advances in Nutrition: An International Review Journal (2014), 5, 104; The American Journal of Clinical Nutrition, (2013), 98, 6; Journal of Feline Medicine and Surgery, (2017); The source of phosphorus influences serum PTH, apparent digestibility and blood levels of calcium and phosphorus in dogs fed high phosphorus diets with balanced Ca/P ratio. Proc. Waltham International Nutritional Sciences Symposium, USA; Clinical aspects of natural and added phosphorus in foods, 2017, Springer Science+Business, Media)...
April 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29604592/quercus-dilatata-lindl-ex-royle-ameliorates-bpa-induced-hepatotoxicity-in-sprague-dawley-rats
#10
Syeda Tayyaba Batool Kazmi, Muhammad Majid, Sonia Maryam, Aymen Rahat, Madiha Ahmed, Muhammad Rashid Khan, Ihsan Ul Haq
Quercus dilatata Lindl. ex Royle was evaluated for in vitro polyphenol content and antioxidant potential as well as in vivo protective role against bisphenol A (BPA) induced hepatotoxicity. The distilled water-acetone (QDDAE) and methanol-ethyl acetate (QDMEtE) extracts were standardized and administered in high (300 mg/kg body weight (BW) and low (150 mg/kg BW) doses to Sprague Dawley rats, injected with BPA (25 mg/kg BW). Silymarin (50 mg/kg BW) was used as positive control. Subsequently, blood and liver homogenates were collected after four weeks of treatment, and the defensive effects of both extracts against oxidative damage and genotoxicity were assessed via hematological and biochemical investigations, determination of endogenous expression of enzymes as well as levels of free radicals and comet assay...
March 28, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29598998/world-health-organisation-classification-of-lymphoid-tumours-in-veterinary-and-human-medicine-a-comparative-evaluation-of-gastrointestinal-lymphomas-in-61-cats
#11
B Wolfesberger, A Fuchs-Baumgartinger, V Greß, S E Hammer, G Gradner, K Knödl, A Tichy, B C Rütgen, C Beham-Schmid
To diagnose and classify the various entities of lymphomas, the World Health Organisation (WHO) classification is applied in human as well as in veterinary medicine. We validated the concordance of these classification systems by having a veterinary and human pathologist evaluate gastrointestinal lymphoma tissue from 61 cats. In 59% of all cases, there was a match between their respective diagnoses of the lymphoma subtype. A complete consensus between the two evaluators was obtained for all samples with a diagnosis of diffuse large B-cell lymphoma, T-cell anaplastic large cell lymphoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue...
February 2018: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29572939/computed-tomographic-appearance-of-abdominal-lymph-nodes-in-healthy-cats
#12
Michael Perlini, Andrew Bugbee, Scott Secrest
BACKGROUND: Computed tomography (CT) is commonly used in veterinary medicine and plays an important role in disease identification and cancer staging. Identification of abnormal abdominal lymph nodes is important for clinical, therapeutic, and prognostic decision making. No published study describes the CT appearance of abdominal lymph nodes in healthy cats. HYPOTHESIS/OBJECTIVES: All abdominal lymph centers will be identified on CT with the majority of lymph nodes being elongated and homogenously contrast enhancing...
March 23, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29568184/antioxidant-activities-of-basella-alba-aqueous-leave-extract-in-blood-pancreas-and-gonadal-tissues-of-diabetic-male-wistar-rats
#13
Dennis Seyi Arokoyo, Ibukun Peter Oyeyipo, Stefan Simon Du Plessis, Yapo Guillaume Aboua
Background: Oxidative stress is frequently identified as a key element in the pathophysiology of many complications of diabetes mellitus, including reproductive complications. The antioxidant potential of medicinal plants have been suggested for therapeutic focus of diseases in recent reports. Objective: To investigate the effect of Basella alba (Ba) aqueous leave extract on diabetes-induced oxidative stress. Materials and Methods: Forty male Wistar rats (8-10 weeks) were randomly divided into four groups ( n = 10) and treated as follows; Control (C + Ns) and Diabetic (D + Ns) animals received oral normal saline 0...
January 2018: Pharmacognosy Research
https://www.readbyqxmd.com/read/29566442/acvim-consensus-update-on-lyme-borreliosis-in-dogs-and-cats
#14
Meryl P Littman, Bernhard Gerber, Richard E Goldstein, Mary Anna Labato, Michael R Lappin, George E Moore
An update of the 2006 American College of Veterinary Internal Medicine (ACVIM) Small Animal Consensus Statement on Lyme Disease in Dogs: Diagnosis, Treatment, and Prevention was presented at the 2016 ACVIM Forum in Denver, CO, followed by panel and audience discussion and a drafted consensus statement distributed online to diplomates for comment. The updated consensus statement is presented below. The consensus statement aims to provide guidance on the diagnosis, treatment, and prevention of Lyme borreliosis in dogs and cats...
March 22, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29563782/depressive-status-explains-a-significant-amount-of-the-variance-in-copd-assessment-test-cat-scores
#15
Marc Miravitlles, Jesús Molina, José Antonio Quintano, Anna Campuzano, Joselín Pérez, Carlos Roncero
Background: COPD assessment test (CAT) is a short, easy-to-complete health status tool that has been incorporated into the multidimensional assessment of COPD in order to guide therapy; therefore, it is important to understand the factors determining CAT scores. Methods: This is a post hoc analysis of a cross-sectional, observational study conducted in respiratory medicine departments and primary care centers in Spain with the aim of identifying the factors determining CAT scores, focusing particularly on the cognitive status measured by the Mini-Mental State Examination (MMSE) and levels of depression measured by the short Beck Depression Inventory (BDI)...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29563676/an-approach-to-incompatible-cross-matched-red-cells-our-experience-in-a-major-regional-blood-transfusion-center-at-kolkata-eastern-india
#16
Prasun Bhattacharya, Eeshita Samanta, Nowroz Afroza, Archana Naik, Rathindranath Biswas
INTRODUCTION: With the increased utilization of immunohematology (IH) analyzers in the transfusion medicine, type, and screen policy is the method of choice. Still, the importance of routine crossmatching could not be overruled. Here, we tried to understand the clinical conditions and safety of red cell transfusion and their outcomes. MATERIALS AND METHODS: This prospective study was conducted by IH laboratory, Medical College Kolkata, Blood Bank from October 1, 2015 to March 31, 2016...
January 2018: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/29562770/human-amniotic-membrane-and-amniotic-membrane-derived-cells-how-far-are-we-from-their-use-in-regenerative-and-reconstructive-urology
#17
Taja Železnik Ramuta, Mateja Erdani Kreft
Human amniotic membrane (hAM) is the innermost layer of fetal membranes, which surrounds the developing fetus and forms the amniotic cavity. hAM and hAM-derived cells possess many properties that make them suitable for use in regenerative medicine, such as low immunogenicity, promotion of epithelization, anti-inflammatory properties, angiogenic and antiangiogenic properties, antifibrotic properties, antimicrobial properties, and anticancer properties. Many pathological conditions of the urinary tract lead to organ damage or complete loss of function...
January 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29557669/telemonitoring-in-copd-the-chromed-study-a-randomized-clinical-trial
#18
Paul P Walker, Pasquale P Pompilio, Paolo Zanaboni, Trine S Bergmo, Kaiu Prikk, Andrei Malinovschi, Josep M Montserrat, Jo Middlemass, Silvana Šonc, Giulia Munaro, Dorjan Marušič, Ruth Sepper, Roberto Rosso, A Niroshan Siriwardena, Christer Janson, Ramon Farre, Peter M A Calverley, Raffaele L Dellaca'
RATIONALE: Early detection of COPD exacerbations using tele-monitoring of physiological variables might reduce the frequency of hospitalisation. OBJECTIVES: To evaluate the efficacy of home monitoring of lung mechanics by the forced oscillation technique (FOT) and cardiac parameters in older COPD patients with co-morbidities. METHODS: This multicentre, randomized clinical trial recruited 312 GOLD grade II-IV COPD patients (median age 71 years [IQR:66-76], 49...
March 20, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29552845/-exogenous-h%C3%A2-o%C3%A2-regulated-secondary-metabolism-of-scutellaria-baicalensis-and-enhanced-drug-quality
#19
Xiao-Ying Fu, Hui-Min Guo, Wei Cong, Xiang-Cai Meng
The increasing demand of Chinese materia medica could not be supplied by wild resource, and the cultivated medicinal materials become popular, which led to decreased quality of many medicinal materials due to the difference of the circumstance between the wild and the cultivated. How to improve quality becomes key points of Chinese medicine resource. The leaves of Scutellaria baicalensis were sprayed with H₂O₂, the activities of superoxide dismutase (SOD) and catalase (CAT) changed little, but there had been a marked decrease of peroxidase (POD) and ascorbic oxidase (APX), which showed that the antioxidase system declined...
January 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29552354/juvenile-hyposomatotropism-in-a-somali-cat-presenting-with-seizures-due-to-intermittent-hypoglycaemia
#20
Maya Laura König, Diana Henke, Katja Adamik, Cristina Pérez Vera
Case summary: A 3-month-old intact male Somali cat was evaluated for a history of seizures, hypoglycaemia and mental dullness 4 weeks after being bitten in the head by a dog. The cat's body size and weight were approximately half that of his littermates and its haircoat was woolly, with fewer guard hairs. Multiple hypoglycaemic episodes were documented over a period of 4 weeks, which resolved rapidly after correction of the hypoglycaemia. Juvenile hyposomatotropism was presumptively diagnosed by demonstrating low circulating levels of insulin-like growth factor 1 and after exclusion of other endocrine and non-endocrine causes of small stature and hypoglycaemia...
January 2018: JFMS Open Reports
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