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https://www.readbyqxmd.com/read/29224586/a-scoping-review-of-the-evidence-for-efficacy-of-acupuncture-in-companion-animals
#1
Wesley J Rose, Jan M Sargeant, W J Brad Hanna, David Kelton, Dianna M Wolfe, Lee V Wisener
Acupuncture has become increasingly popular in veterinary medicine. Within the scientific literature there is debate regarding its efficacy. Due to the complex nature of acupuncture, a scoping review was undertaken to identify and categorize the evidence related to acupuncture in companion animals (dogs, cats, and horses). Our search identified 843 relevant citations. Narrative reviews represented the largest proportion of studies (43%). We identified 179 experimental studies and 175 case reports/case series that examined the efficacy of acupuncture...
December 11, 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/29220052/hypoglycemic-and-hypolipidemic-effects-of-anthocyanins-extract-from-black-soybean-seed-coat-in-high-fat-diet-and-streptozotocin-induced-diabetic-mice
#2
Zhongqin Chen, Cong Wang, Yuxiang Pan, Xudong Gao, Haixia Chen
Black soybean seed coat extract (BSSCE) is a rich source of anthocyanins with multiple health effects. This study was aimed at investigating the composition and hypoglycemic and hypolipidemic effects of BSSCE in vitro and in a high-fat diet and streptozotocin (STZ)-induced diabetic mice. The anthocyanins of BSSCE were identified as cyanidin-3-O-glucoside, delphinidin-3-O-glucoside, and peonidin-3-O-glucoside by HPLC-MS. Results demonstrated that BSSCE exhibited strong inhibitory activities for α-amylase, potent inhibition activity against lipid accumulation in HepG2 cells and protection effect on H2O2-induced oxidative stress-damaged HepG2 cells...
December 8, 2017: Food & Function
https://www.readbyqxmd.com/read/29217164/the-protective-role-of-crocin-in-tartrazine-induced-nephrotoxicity-in-wistar-rats
#3
Mehmet Erman Erdemli, Mehmet Gul, Eyup Altinoz, Emrah Zayman, Zeynep Aksungur, Harika Gozukara Bag
The present study was conducted to investigate the changes in rat kidney tissues after administration of tartrazine (T) and crocine (Cr). The latter was applied for its protective properties. The present study was conducted with the approval of Inonu University, Faculty of Medicine, Experimental Animals Ethics Committee. Forty rats were randomly divided into 4 equal groups (Control, T, Cr, T + Cr). At the end of the experiment, the rats were decapitated. Biochemical and histopathological studies were conducted on excised rat kidney tissues...
December 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29215573/the-use-of-liposomes-and-nanoparticles-as-drug-delivery-systems-to-improve-cancer-treatment-in-dogs-and-cats
#4
REVIEW
Katarzyna Zabielska-Koczywąs, Roman Lechowski
BACKGROUND: Cancer remains a leading cause of death in companion animals. In human medicine, liposomes and nanoparticles have been extensively investigated as drug delivery systems (DDS) for anticancer agents due to their ability to target cancerous cells and reduce the negative side effects of free cytostatic drugs. In this review, the authors discuss the results of clinical trials using liposomes and polymer-based nanoparticles as DDS to improve cancer treatment in dogs and cats, indicating which ones seem worth further evaluation...
December 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29199582/antidiabetic-properties-of-the-tiger-s-milk-medicinal-mushroom-lignosus-rhinocerotis-agaricomycetes-in-streptozotocin-induced-diabetic-rats
#5
Kar Lin Nyam, Cheng Fhai Chow, Chon Seng Tan, Szu Ting Ng
Diabetes mellitus is a major cause of morbidity and mortality worldwide. Although scientific evidence supporting its therapeutic efficacy is lacking, the use of the tiger's milk mushroom (TGM; Lignosus rhinocerotis), which is native to tropical areas such as Malaysia, Indonesia, and the Philippines, has been found to contain a very large amount of potential antioxidants. In this study, rats were weighed and then intravenously injected with 35 mg/kg streptozotocin (STZ). Rats were left for 1 week before blood glucose concentrations were measured to determine the onset of diabetes before the next procedure was conducted...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29190192/suspected-zonisamide-related-anticonvulsant-hypersensitivity-syndrome-in-a-cat
#6
Audrey Collinet, Veronique Sammut
CASE DESCRIPTION A 2-year-old neutered male domestic shorthair cat was evaluated for sudden onset of cluster seizures. CLINICAL FINDINGS At an emergency clinic, the cat had hyperimmunoglobulinemia and thrombocytopenia. On referral, treatment with levetiracetam, zonisamide, and phenobarbital initially provided good control of cluster seizure activity (attributable to epilepsy of unknow origin). Two weeks later, assessments revealed that serum phenobarbital concentration was within the ideal range but serum zonisamide concentration exceeded the recommended therapeutic range...
December 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29174044/repeatability-of-contrast-enhanced-ultrasonography-of-the-kidneys-in-healthy-cats
#7
Emmelie Stock, Luc Duchateau, Jimmy H Saunders, Veerle Volckaert, Ingeborgh Polis, Katrien Vanderperren
Contrast-enhanced ultrasound can be used to image and quantify tissue perfusion. It holds great potential for the use in the diagnosis of various diffuse renal diseases in both human and veterinary medicine. Nevertheless, the technique is known to have an inherent relatively high variability, related to various factors associated with the patient, the contrast agent and machine settings. Therefore, the aim of this study was to assess week-to-week intra- and inter-cat variation of several perfusion parameters obtained with CEUS of both kidneys of 12 healthy cats...
November 21, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29172873/retrospective-evaluation-of-toceranib-phosphate-palladia-use-in-cats-with-mast-cell-neoplasia
#8
Erika P Berger, Chad M Johannes, Gerald S Post, Gillian Rothchild, Kai-Biu Shiu, Sarah Wetzel, Leslie E Fox
Objectives The purpose of this study was to solicit and compile data from practicing veterinary specialists regarding their use of toceranib in cats with mast cell neoplasia and to provide initial assessment of possible clinical benefit and adverse events. Methods The American College of Veterinary Internal Medicine and Oncology listservs were used to solicit data pertaining to cases in which toceranib was used in the treatment of feline mast cell neoplasia. Cases were included if the following data were received: signalment (age, sex, breed), diagnosis of mast cell neoplasia by either cytology or histopathology, anatomic classification of disease (cutaneous, splenic/hepatic, gastrointestinal, other), previous and concurrent treatment, toceranib dose (mg/kg) and schedule, duration of therapy, best response and documentation of adverse events...
March 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29171085/contrast-enhanced-ultrasound-examination-for-the-assessment-of-renal-perfusion-in-cats-with-chronic-kidney-disease
#9
E Stock, D Paepe, S Daminet, E Vandermeulen, L Duchateau, J H Saunders, K Vanderperren
BACKGROUND: Contrast-enhanced ultrasound examination (CEUS) is a functional imaging technique allowing noninvasive assessment of tissue perfusion. Studies in humans show that the technique holds great potential to be used in the diagnosis of chronic kidney disease (CKD). However, data in veterinary medicine are currently lacking. OBJECTIVES: To evaluate renal perfusion using CEUS in cats with CKD. ANIMALS: Fourteen client-owned cats with CKD and 43 healthy control cats...
November 24, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29159852/orbital-invasive-squamous-cell-carcinoma-with-adnexal-involvement-clinically-mimicking-feline-restrictive-orbital-myofibroblastic-sarcoma-19-cases-1990-2016
#10
Kathryn A Diehl, Silvia G Pryor, Leandro Bc Teixeira
OBJECTIVE: To describe the clinical presentations of patients diagnosed with ocular adnexal or orbital squamous cell carcinoma (SCC), which possess features similar to feline restrictive orbital myofibroblastic sarcoma (FROMS). PROCEDURES: A retrospective review of adnexal and/or orbital SCC was performed. Cases were collected from the University of Georgia College of Veterinary Medicine and the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) (1990-2016)...
November 21, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29153104/development-and-preliminary-psychometric-evaluation-of-an-owner-completed-measure-of-feline-quality-of-life
#11
Sophi Tatlock, Margaret Gober, Nicola Williamson, Rob Arbuckle
Due to improved healthcare and pet longevity, measurement of health-related quality of life (HRQoL) is increasingly important in companion animal medicine. The aim of this study was to develop and evaluate the content and psychometric properties of an owner-completed assessment of health and quality of life (QoL) in cats for use in general veterinary clinical practice. A 23-item feline QoL measure, drafted based on findings from an online survey completed by 45 pet owners, was revised following qualitative interviews with 10 pet owners of healthy cats to assess content validity...
October 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29152258/in-vitro-screening-of-neuroprotective-activity-of-indian-medicinal-plant-withania-somnifera
#12
Manjeet Singh, Charles Ramassamy
Canine cognitive dysfunction (CCD) is an age-dependent neurodegenerative condition characterised by changes in decline in learning and memory patterns. The neurodegenerative features of CCD in ageing dogs and cats are similar to human ageing and Alzheimer's disease (AD). Discovering neuroprotective disease-modifying therapies against CCD and AD is a major challenge. Strong evidence supports the role of amyloid β peptide deposition and oxidative stress in the pathophysiology of CCD and AD. In both the human and canine brain, oxidative damage progressively increases with age...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29145786/cephalexin-susceptibility-breakpoint-for-veterinary-isolates-clinical-laboratory-standards-institute-revision
#13
Mark G Papich, Cindy Lindeman
The Clinical and Laboratory Standards Institute (CLSI) uses cephalothin as the class representative for testing veterinary isolates for susceptibility to other first-generation cephalosporins, including cephalexin. We examined replacing cephalothin with cephalexin because cephalexin is used more often clinically. Bacterial isolates were obtained from dogs and cats from a national surveillance program. CLSI testing methods were used to determine the MIC for 4 cephalosporins used in veterinary medicine. Cephalexin clinical breakpoints for canine isolates were established by using published pharmacokinetic data and Monte Carlo simulations to calculate the probability of target attainment (PTA)...
November 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29142416/protective-effect-of-pluchea-lanceolata-against-aluminum-chloride-induced-neurotoxicity-in-swiss-albino-mice
#14
Ravi Mundugaru, Senthilkumar Sivanesan, Padmaja Udaykumar, Niranjan Rao, Naveen Chandra
Background: Aluminum chloride (AlCl3) is a known potent environmental neurotoxin causing progressive neurodegenerative changes in the brain. The herb Pluchea lanceolata is commonly known as "Rasana" and used as a nerve tonic in neuroinflammatory conditions in Indian system of medicine. Objective: To evaluate the neuroprotective activity of hydroalcoholic extract of P. lanceolata in chronic AlCl3-induced neurotoxicity in Swiss albino mice. Materials and Methods: Albino mice were categorized into four different groups; Group 1served as vehicle control, Group 2 mice were administered with AlCl3, 40 mg/kg body weight by intraperitoneal route for 45 consecutive days...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29136156/increase-in-antimicrobial-resistance-and-emergence-of-major-international-high-risk-clonal-lineages-in-dogs-and-cats-with-urinary-tract-infection-16-year-retrospective-study
#15
Cátia Marques, Adriana Belas, Andreia Franco, Catarina Aboim, Luís Telo Gama, Constança Pomba
Objectives: To evaluate temporal trends in antimicrobial resistance, over 16 years, in bacteria isolated from dogs and cats with urinary tract infection (UTI) and the clonal lineages of bacteria harbouring critical antimicrobial resistance mechanisms. Methods: Antimicrobial susceptibility testing was conducted for 948 bacteria isolated from dogs and cats with UTI (1999-2014). Resistance mechanisms were detected by PCR, namely ESBL/AmpC in third-generation cephalosporin (3GC)-resistant Escherichia coli and Proteus mirabilis, mecA in methicillin-resistant staphylococci, and aac(6')-Ieaph(2″)-Ia and aph(2″)-1d in high-level gentamicin-resistant (HLGR) enterococci...
November 9, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29132621/effect-of-computer-use-on-physician-patient-communication-using-a-validated-instrument-patient-perspective
#16
Issam Shaarani, Rim Taleb, Jumana Antoun
BACKGROUND: Physician-patient communication is essential in the physician-patient relationship. Concerns were raised about the impact of the computer on this relationship with the increase in use of electronic medical records (EMR). Most studies addressed the physician's perspective and only few explored the patient's perspective. AIM: This study aims to assess the patient's perspective of the effect of the physician's computer use during the clinical encounter on the interpersonal and communication skills of the physician using a validated communication assessment tool (CAT)...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29128859/-vigilance-for-veterinary-medicinal-products-reports-of-adverse-reactions-in-the-year-2016
#17
C R Müntener, C Müntener, J Kupper, H Naegeli, B Gassner
A total of 253 reports of adverse reactions to veterinary medicinal products were received during the year 2016 representing a decrease of 13% compared to the previous year (292 reports). The majority of the reports described reactions affecting companion animals (178 dogs and 32 cats) as well as cattle (17 reports) and horses (10 reports). Most of the reactions reported were linked to the use of antiparasitics (145 reports), hormone products (26 reports) and antiinfectives (10 reports). 32 reports were generated from consultations with Tox Info Suisse in Zürich and involved mainly the excessive intake of flavoured tablets and, in some cases, the use of reconverted products (applied to another species than that authorized)...
November 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29102461/effect-of-swarna-jibanti-coelogyne-cristata-lindley-in-alleviation-of-chronic-fatigue-syndrome-in-aged-wistar-rats
#18
Achintya Mitra, Tapas Kumar Sur, Sachhidananda Upadhyay, Dipankar Bhattacharyya, Jayram Hazra
BACKGROUND: Swarna Jibanti scientifically known as Coelogyne cristata Lindley (Orchidaceae), an orchid mentioned in Ayurvedic medicine is used to promote healthy life span. OBJECTIVE: The present work was planned to study the efficacy of hydro-alcoholic extract of pseudobulbs of C.cristata (CCE) to assess its role on chronic fatigue syndrome (CFS) induced behavioural and biochemical changes in aged Wistar rats compared to Panax ginseng (PG), a prototype anti-stress agent...
November 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29102120/antimicrobial-resistance-in-clinical-escherichia-coli-isolated-from-companion-animals-in-australia
#19
Sugiyono Saputra, David Jordan, Tahlia Mitchell, Hui San Wong, Rebecca J Abraham, Amanda Kidsley, John Turnidge, Darren J Trott, Sam Abraham
Multidrug-resistant (MDR) Escherichia coli have become a major public health concern to both humans and animal health. While the frequency of antimicrobial resistance (AMR) in clinical E. coli is monitored regularly in human medicine, current frequency of AMR in companion animals remains unknown in Australia. In this study we conducted antimicrobial susceptibility testing (AST) and where possible, determined potential risk factors for MDR infection among 883 clinical Escherichia coli isolated from dogs (n=514), cats (n=341) and horses (n=28)...
November 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29093434/supplementation-with-achyrocline-satureioides-inflorescence-extracts-to-pregnant-and-breastfeeding-rats-induces-tissue-specific-changes-in-enzymatic-activity-and-lower-neonatal-survival
#20
Karla Suzana Moresco, Alexandre Kleber Silveira, Carlos Eduardo Schnorr, Fares Zeidán-Chuliá, Rafael Calixto Bortolin, Leonardo da Silva Bittencourt, Moara Mingori, Luana Heimfarth, Thallita Kelly Rabelo, Maurilio da Silva Morrone, Juliana Poglia Carini, Daniel Pens Gelain, Valquiria Linck Bassani, José Cláudio Fonseca Moreira
Achyrocline satureioides (AS, family Asteraceae) is a plant widely used in traditional medicine for stomach, digestive, and gastrointestinal disorders during pregnancy. Studies regarding the indiscriminate use of plant infusions during pregnancy are limited. Recent reports have shown that chronic flavonoid supplementation induces toxicity in vivo and raises the mortality rates of healthy subjects. Therefore, we investigated whether supplementation of pregnant and lactating Wistar rats with two AS inflorescence extracts, consisting of an aqueous (AQ) extract similar to a tea (47 mg·kg(-1)·day) and a hydroethanolic (HA) extract (35 mg·kg(-1)·day(-1)) with a higher flavonoid content, could induce redox-related side effects...
August 29, 2017: Biomedicines
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